NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|696580366|ref|WP_033111545|]
View 

NAD(P)/FAD-dependent oxidoreductase [Dickeya dadantii]

Protein Classification

NAD(P)/FAD-dependent oxidoreductase( domain architecture ID 12024463)

NAD(P)/FAD-dependent oxidoreductase catalyzes the transfer of electrons from one molecule, the electron donor or reductant, to another molecule, the electron acceptor or oxidant; similar to flavin-containing L-amino-acid oxidase that catalyzes the oxidative deamination of predominantly hydrophobic and aromatic L-amino acids

CATH:  3.50.50.60
EC:  1.-.-.-
Gene Ontology:  GO:0016491|GO:0009055
PubMed:  10944103

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Amino_oxidase pfam01593
Flavin containing amine oxidoreductase; This family consists of various amine oxidases, ...
 53-541 1.88e-93

Flavin containing amine oxidoreductase; This family consists of various amine oxidases, including maze polyamine oxidase (PAO)and various flavin containing monoamine oxidases (MAO). The aligned region includes the flavin binding site of these enzymes. The family also contains phytoene dehydrogenases and related enzymes. In vertebrates MAO plays an important role regulating the intracellular levels of amines via there oxidation; these include various neurotransmitters, neurotoxins and trace amines. In lower eukaryotes such as aspergillus and in bacteria the main role of amine oxidases is to provide a source of ammonium. PAOs in plants, bacteria and protozoa oxidase spermidine and spermine to an aminobutyral, diaminopropane and hydrogen peroxide and are involved in the catabolism of polyamines. Other members of this family include tryptophan 2-monooxygenase, putrescine oxidase, corticosteroid binding proteins and antibacterial glycoproteins.


:

Pssm-ID: 396255 [Multi-domain]  Cd Length: 446  Bit Score: 293.24  E-value: 1.88e-93
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580366   53 ISGLVAATELLRAGVkDITLFEARDRrIGGRVWSQTFDprypHLIAEMGAMRFPSSETCLFYYLNKLDIATTTSFPDPGV 132
Cdd:pfam01593   1 LAGLAAARELLRAGH-DVTVLEARDR-VGGRIRTVRDD----GFLIELGAMWFHGAQPPLLALLKELGLEDRLVLPDPAP 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580366  133 VDTELHYRGVRHiwsagdppPSLFSRVHEGWVALLNEGYLHNgvplvaprdITAMLKSHcfdKARKAWQAWlDAFRDYSF 212
Cdd:pfam01593  75 FYTVLFAGGRRY--------PGDFRRVPAGWEGLLEFGRLLS---------IPEKLRLG---LAALASDAL-DEFDLDDF 133

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580366  213 YSALVTMFTSNTPPGGV-PWRRPDDFELFGSLGIGSGGFL---PVYQAGFTEILRLVINGYEDDQRLIIGGISTLAERLV 288
Cdd:pfam01593 134 SLAESLLFLGRRGPGDVeVWDRLIDPELFAALPFASGAFAgdpSELSAGLALPLLWALLGEGGSLLLPRGGLGALPDALA 213

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580366  289 SQKIG-DTRLSEhicfnEVKRIYKEDGEIKLVSGKGQTHTFDRVIVTSSTRTMQIVHCLTGdetfLEHDISRAVKETHLT 367
Cdd:pfam01593 214 AQLLGgDVRLNT-----RVRSIDREGDGVTVTLTDGEVIEADAVIVTVPLGVLKRILFTPP----LPPEKARAIRNLGYG 284

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580366  368 GSSKLFMLTRNKFWLNDSL--PVTIQSDGFIRGVYCLDYEPDNPDGPGVVLLSYTWEDDAHKLLSIPDKKQRCQYLVDDL 445
Cdd:pfam01593 285 PVNKVHLEFDRKFWPDLGLlgLLSELLTGLGTAFSWLTFPNRAPPGKGLLLLVYVGPGDRARELEGLSDEELLQAVLRDL 364

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580366  446 AKinpefarhLIPADGDYERYVLHHDWLVDPYSAGAFKLNYPGedvySQRLFFQFKNAntpEKDTGLYLAGCGCS--FTG 523
Cdd:pfam01593 365 RK--------LFGEEAPEPLRVLVSDWHTDPWPRGSYSLPQYG----PGHDDYRPLAR---TPDPGLFFAGEHTStgYPG 429

                         490
                  ....*....|....*...
gi 696580366  524 GwIEGAMQTALNSACAVI 541
Cdd:pfam01593 430 T-VEGAIESGRRAARAVL 446
 
Name Accession Description Interval E-value
Amino_oxidase pfam01593
Flavin containing amine oxidoreductase; This family consists of various amine oxidases, ...
 53-541 1.88e-93

Flavin containing amine oxidoreductase; This family consists of various amine oxidases, including maze polyamine oxidase (PAO)and various flavin containing monoamine oxidases (MAO). The aligned region includes the flavin binding site of these enzymes. The family also contains phytoene dehydrogenases and related enzymes. In vertebrates MAO plays an important role regulating the intracellular levels of amines via there oxidation; these include various neurotransmitters, neurotoxins and trace amines. In lower eukaryotes such as aspergillus and in bacteria the main role of amine oxidases is to provide a source of ammonium. PAOs in plants, bacteria and protozoa oxidase spermidine and spermine to an aminobutyral, diaminopropane and hydrogen peroxide and are involved in the catabolism of polyamines. Other members of this family include tryptophan 2-monooxygenase, putrescine oxidase, corticosteroid binding proteins and antibacterial glycoproteins.


Pssm-ID: 396255 [Multi-domain]  Cd Length: 446  Bit Score: 293.24  E-value: 1.88e-93
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580366   53 ISGLVAATELLRAGVkDITLFEARDRrIGGRVWSQTFDprypHLIAEMGAMRFPSSETCLFYYLNKLDIATTTSFPDPGV 132
Cdd:pfam01593   1 LAGLAAARELLRAGH-DVTVLEARDR-VGGRIRTVRDD----GFLIELGAMWFHGAQPPLLALLKELGLEDRLVLPDPAP 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580366  133 VDTELHYRGVRHiwsagdppPSLFSRVHEGWVALLNEGYLHNgvplvaprdITAMLKSHcfdKARKAWQAWlDAFRDYSF 212
Cdd:pfam01593  75 FYTVLFAGGRRY--------PGDFRRVPAGWEGLLEFGRLLS---------IPEKLRLG---LAALASDAL-DEFDLDDF 133

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580366  213 YSALVTMFTSNTPPGGV-PWRRPDDFELFGSLGIGSGGFL---PVYQAGFTEILRLVINGYEDDQRLIIGGISTLAERLV 288
Cdd:pfam01593 134 SLAESLLFLGRRGPGDVeVWDRLIDPELFAALPFASGAFAgdpSELSAGLALPLLWALLGEGGSLLLPRGGLGALPDALA 213

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580366  289 SQKIG-DTRLSEhicfnEVKRIYKEDGEIKLVSGKGQTHTFDRVIVTSSTRTMQIVHCLTGdetfLEHDISRAVKETHLT 367
Cdd:pfam01593 214 AQLLGgDVRLNT-----RVRSIDREGDGVTVTLTDGEVIEADAVIVTVPLGVLKRILFTPP----LPPEKARAIRNLGYG 284

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580366  368 GSSKLFMLTRNKFWLNDSL--PVTIQSDGFIRGVYCLDYEPDNPDGPGVVLLSYTWEDDAHKLLSIPDKKQRCQYLVDDL 445
Cdd:pfam01593 285 PVNKVHLEFDRKFWPDLGLlgLLSELLTGLGTAFSWLTFPNRAPPGKGLLLLVYVGPGDRARELEGLSDEELLQAVLRDL 364

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580366  446 AKinpefarhLIPADGDYERYVLHHDWLVDPYSAGAFKLNYPGedvySQRLFFQFKNAntpEKDTGLYLAGCGCS--FTG 523
Cdd:pfam01593 365 RK--------LFGEEAPEPLRVLVSDWHTDPWPRGSYSLPQYG----PGHDDYRPLAR---TPDPGLFFAGEHTStgYPG 429

                         490
                  ....*....|....*...
gi 696580366  524 GwIEGAMQTALNSACAVI 541
Cdd:pfam01593 430 T-VEGAIESGRRAARAVL 446
YobN COG1231
Monoamine oxidase [Amino acid transport and metabolism];
42-546 1.75e-83

Monoamine oxidase [Amino acid transport and metabolism];


Pssm-ID: 440844 [Multi-domain]  Cd Length: 440  Bit Score: 267.17  E-value: 1.75e-83
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580366  42 PTPRVAIIGAGISGLVAATELLRAGVkDITLFEARDrRIGGRVWSQTFDPryPHLIAEMGAMRFPSSETCLFYYLNKLDI 121
Cdd:COG1231    6 RGKDVVIVGAGLAGLAAARELRKAGL-DVTVLEARD-RVGGRVWTLRFGD--DGLYAELGAMRIPPSHTNLLALARELGL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580366 122 ATTTSFPDPGvvDTELHYRGVRHIWSAGDpppSLFSRVHEGWVALLNEgylhngvplvaprditamlkshcFDKARKAWQ 201
Cdd:COG1231   82 PLEPFPNENG--NALLYLGGKRVRAGEIA---ADLRGVAELLAKLLRA-----------------------LAAALDPWA 133

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580366 202 AWLDAFRDYSFYSALVTmftsntpPGGVPWRRpddfELFGSLGIGSGGfLPVYQAGFTEILRLV-INGYEDDQRLIIGGI 280
Cdd:COG1231  134 HPAAELDRESLAEWLRR-------NGASPSAR----RLLGLLGAGEYG-ADPDELSLLDLLRYAaSAGGGAQQFRIVGGM 201

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580366 281 STLAERLVSQkigdtrLSEHICFN-EVKRIYKEDGEIKLVSGKGQTHTFDRVIVTSSTRTMQIVHCLTGdetfLEHDISR 359
Cdd:COG1231  202 DQLPRALAAE------LGDRIRLGaPVTRIRQDGDGVTVTTDDGGTVRADAVIVTVPPSVLRRIEFDPP----LPAAKRA 271

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580366 360 AVKETHLTGSSKLFMLTRNKFWLNDSL-PVTIQSDGFIRGVYCLDYepdNPDGPGVVLLSYTWEDDAHKLLSIPDkKQRC 438
Cdd:COG1231  272 AIQRLPYGAAIKVFLQFDRPFWEEDGLyGGISLTDLPIRQTWYPSN---GPDGGAGVLLGYVGGDDARALAALSP-EERV 347

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580366 439 QYLVDDLAKINPEFARHLIpadgdyeRYVlHHDWLVDPYSAGAFKLNYPGEDVYSQRLFfqfknantPEKDTGLYLAGCG 518
Cdd:COG1231  348 AAALEQLARIFGVYAAEPV-------DYV-STDWGRDPWSRGAYAAAPPGQLTAAGPAL--------AEPDGRIHFAGEH 411

                        490       500
                 ....*....|....*....|....*....
gi 696580366 519 CSFTG-GWIEGAMQTALNSACAVIRSSGG 546
Cdd:COG1231  412 TSDEWpGWVEGALESGERAAAEILARLGG 440
PRK07233 PRK07233
hypothetical protein; Provisional
 45-454 1.82e-10

hypothetical protein; Provisional


Pssm-ID: 235977 [Multi-domain]  Cd Length: 434  Bit Score: 62.98  E-value: 1.82e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580366  45 RVAIIGAGISGLVAATELLRAGvKDITLFEARDrRIGGRVWSQTFD----PRYPH-----------LIAEMG---AMRFP 106
Cdd:PRK07233   1 KIAIVGGGIAGLAAAYRLAKRG-HEVTVFEADD-QLGGLAASFEFGglpiERFYHhifksdealleLLDELGledKLRWR 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580366 107 SSETClFYYLNKL-DIATTTSFpdpgvvdteLHYrgvrhiwsagdPPPSLFSRVHEGWVALLNeGYLHNGVPLvapRDIT 185
Cdd:PRK07233  79 ETKTG-YYVDGKLyPLGTPLEL---------LRF-----------PHLSLIDKFRLGLLTLLA-RRIKDWRAL---DKVP 133

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580366 186 AM--LKSHCFDKA-RKAWQAWLDA-FRDYS-------FYSALVtmFTSNtppggvpwRRPDdfelfgslgigsggflpvy 254
Cdd:PRK07233 134 AEewLRRWSGEGVyEVFWEPLLESkFGDYAddvsaawLWSRIK--RRGN--------RRYS------------------- 184

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580366 255 qaGFTEILrlvinGYEDdqrliiGGISTLAERLVsQKIGdtRLSEHICFN-EVKRIYKEDGEIKLVSGKGQTHTFDRVIV 333
Cdd:PRK07233 185 --LFGEKL-----GYLE------GGFATLIDALA-EAIE--ARGGEIRLGtPVTSVVIDGGGVTGVEVDGEEEDFDAVIS 248

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580366 334 TSSTrtmQIVHCLTGDETFLEHDISRAVKethLTGSSKLFMLTR----NKFWLN---DSLPVT--IQSDGFIrgvycldy 404
Cdd:PRK07233 249 TAPP---PILARLVPDLPADVLARLRRID---YQGVVCMVLKLRrpltDYYWLNindPGAPFGgvIEHTNLV-------- 314

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|...
gi 696580366 405 EPDNPDGPGVVLL-SYTweDDAHKLLSIPDK--KQRCqylVDDLAKINPEFAR 454
Cdd:PRK07233 315 PPERYGGEHLVYLpKYL--PGDHPLWQMSDEelLDRF---LSYLRKMFPDFDR 362
proto_IX_ox TIGR00562
protoporphyrinogen oxidase; This enzyme oxidizes protoporphyrinogen IX to protoporphyrin IX, a ...
 42-90 2.61e-04

protoporphyrinogen oxidase; This enzyme oxidizes protoporphyrinogen IX to protoporphyrin IX, a precursor of heme and chlorophyll. Bacillus subtilis HemY also has coproporphyrinogen III to coproporphyrin III oxidase activity in a heterologous expression system, although the role for this activity in vivo is unclear. This protein is a flavoprotein and has a beta-alpha-beta dinucleotide binding motif near the amino end. [Biosynthesis of cofactors, prosthetic groups, and carriers, Heme, porphyrin, and cobalamin]


Pssm-ID: 213540 [Multi-domain]  Cd Length: 462  Bit Score: 43.67  E-value: 2.61e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 696580366   42 PTPRVAIIGAGISGLVAA----TELLRAGVkDITLFEARDrRIGGrvWSQTFD 90
Cdd:TIGR00562   1 GKKHVVIIGGGISGLCAAyyleKEIPELPV-ELTLVEASD-RVGG--KIQTVK 49
AlaDh_PNT_C smart01002
Alanine dehydrogenase/PNT, C-terminal domain; Alanine dehydrogenase catalyzes the ...
 38-99 5.87e-03

Alanine dehydrogenase/PNT, C-terminal domain; Alanine dehydrogenase catalyzes the NAD-dependent reversible reductive amination of pyruvate into alanine.


Pssm-ID: 214966 [Multi-domain]  Cd Length: 149  Bit Score: 37.49  E-value: 5.87e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 696580366    38 PPGIPTPRVAIIGAGISGLVAATELLRAGVkDITLF---EARDRRI----GGRVWSQTfdpRYPHLIAE 99
Cdd:smart01002  15 AGGVPPAKVVVIGAGVVGLGAAATAKGLGA-EVTVLdvrPARLRQLesllGARFTTLY---SQAELLEE 79
 
Name Accession Description Interval E-value
Amino_oxidase pfam01593
Flavin containing amine oxidoreductase; This family consists of various amine oxidases, ...
 53-541 1.88e-93

Flavin containing amine oxidoreductase; This family consists of various amine oxidases, including maze polyamine oxidase (PAO)and various flavin containing monoamine oxidases (MAO). The aligned region includes the flavin binding site of these enzymes. The family also contains phytoene dehydrogenases and related enzymes. In vertebrates MAO plays an important role regulating the intracellular levels of amines via there oxidation; these include various neurotransmitters, neurotoxins and trace amines. In lower eukaryotes such as aspergillus and in bacteria the main role of amine oxidases is to provide a source of ammonium. PAOs in plants, bacteria and protozoa oxidase spermidine and spermine to an aminobutyral, diaminopropane and hydrogen peroxide and are involved in the catabolism of polyamines. Other members of this family include tryptophan 2-monooxygenase, putrescine oxidase, corticosteroid binding proteins and antibacterial glycoproteins.


Pssm-ID: 396255 [Multi-domain]  Cd Length: 446  Bit Score: 293.24  E-value: 1.88e-93
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580366   53 ISGLVAATELLRAGVkDITLFEARDRrIGGRVWSQTFDprypHLIAEMGAMRFPSSETCLFYYLNKLDIATTTSFPDPGV 132
Cdd:pfam01593   1 LAGLAAARELLRAGH-DVTVLEARDR-VGGRIRTVRDD----GFLIELGAMWFHGAQPPLLALLKELGLEDRLVLPDPAP 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580366  133 VDTELHYRGVRHiwsagdppPSLFSRVHEGWVALLNEGYLHNgvplvaprdITAMLKSHcfdKARKAWQAWlDAFRDYSF 212
Cdd:pfam01593  75 FYTVLFAGGRRY--------PGDFRRVPAGWEGLLEFGRLLS---------IPEKLRLG---LAALASDAL-DEFDLDDF 133

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580366  213 YSALVTMFTSNTPPGGV-PWRRPDDFELFGSLGIGSGGFL---PVYQAGFTEILRLVINGYEDDQRLIIGGISTLAERLV 288
Cdd:pfam01593 134 SLAESLLFLGRRGPGDVeVWDRLIDPELFAALPFASGAFAgdpSELSAGLALPLLWALLGEGGSLLLPRGGLGALPDALA 213

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580366  289 SQKIG-DTRLSEhicfnEVKRIYKEDGEIKLVSGKGQTHTFDRVIVTSSTRTMQIVHCLTGdetfLEHDISRAVKETHLT 367
Cdd:pfam01593 214 AQLLGgDVRLNT-----RVRSIDREGDGVTVTLTDGEVIEADAVIVTVPLGVLKRILFTPP----LPPEKARAIRNLGYG 284

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580366  368 GSSKLFMLTRNKFWLNDSL--PVTIQSDGFIRGVYCLDYEPDNPDGPGVVLLSYTWEDDAHKLLSIPDKKQRCQYLVDDL 445
Cdd:pfam01593 285 PVNKVHLEFDRKFWPDLGLlgLLSELLTGLGTAFSWLTFPNRAPPGKGLLLLVYVGPGDRARELEGLSDEELLQAVLRDL 364

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580366  446 AKinpefarhLIPADGDYERYVLHHDWLVDPYSAGAFKLNYPGedvySQRLFFQFKNAntpEKDTGLYLAGCGCS--FTG 523
Cdd:pfam01593 365 RK--------LFGEEAPEPLRVLVSDWHTDPWPRGSYSLPQYG----PGHDDYRPLAR---TPDPGLFFAGEHTStgYPG 429

                         490
                  ....*....|....*...
gi 696580366  524 GwIEGAMQTALNSACAVI 541
Cdd:pfam01593 430 T-VEGAIESGRRAARAVL 446
YobN COG1231
Monoamine oxidase [Amino acid transport and metabolism];
42-546 1.75e-83

Monoamine oxidase [Amino acid transport and metabolism];


Pssm-ID: 440844 [Multi-domain]  Cd Length: 440  Bit Score: 267.17  E-value: 1.75e-83
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580366  42 PTPRVAIIGAGISGLVAATELLRAGVkDITLFEARDrRIGGRVWSQTFDPryPHLIAEMGAMRFPSSETCLFYYLNKLDI 121
Cdd:COG1231    6 RGKDVVIVGAGLAGLAAARELRKAGL-DVTVLEARD-RVGGRVWTLRFGD--DGLYAELGAMRIPPSHTNLLALARELGL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580366 122 ATTTSFPDPGvvDTELHYRGVRHIWSAGDpppSLFSRVHEGWVALLNEgylhngvplvaprditamlkshcFDKARKAWQ 201
Cdd:COG1231   82 PLEPFPNENG--NALLYLGGKRVRAGEIA---ADLRGVAELLAKLLRA-----------------------LAAALDPWA 133

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580366 202 AWLDAFRDYSFYSALVTmftsntpPGGVPWRRpddfELFGSLGIGSGGfLPVYQAGFTEILRLV-INGYEDDQRLIIGGI 280
Cdd:COG1231  134 HPAAELDRESLAEWLRR-------NGASPSAR----RLLGLLGAGEYG-ADPDELSLLDLLRYAaSAGGGAQQFRIVGGM 201

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580366 281 STLAERLVSQkigdtrLSEHICFN-EVKRIYKEDGEIKLVSGKGQTHTFDRVIVTSSTRTMQIVHCLTGdetfLEHDISR 359
Cdd:COG1231  202 DQLPRALAAE------LGDRIRLGaPVTRIRQDGDGVTVTTDDGGTVRADAVIVTVPPSVLRRIEFDPP----LPAAKRA 271

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580366 360 AVKETHLTGSSKLFMLTRNKFWLNDSL-PVTIQSDGFIRGVYCLDYepdNPDGPGVVLLSYTWEDDAHKLLSIPDkKQRC 438
Cdd:COG1231  272 AIQRLPYGAAIKVFLQFDRPFWEEDGLyGGISLTDLPIRQTWYPSN---GPDGGAGVLLGYVGGDDARALAALSP-EERV 347

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580366 439 QYLVDDLAKINPEFARHLIpadgdyeRYVlHHDWLVDPYSAGAFKLNYPGEDVYSQRLFfqfknantPEKDTGLYLAGCG 518
Cdd:COG1231  348 AAALEQLARIFGVYAAEPV-------DYV-STDWGRDPWSRGAYAAAPPGQLTAAGPAL--------AEPDGRIHFAGEH 411

                        490       500
                 ....*....|....*....|....*....
gi 696580366 519 CSFTG-GWIEGAMQTALNSACAVIRSSGG 546
Cdd:COG1231  412 TSDEWpGWVEGALESGERAAAEILARLGG 440
COG3349 COG3349
Uncharacterized protein, contains NAD-binding domain and a Fe-S cluster [General function ...
 42-333 2.29e-14

Uncharacterized protein, contains NAD-binding domain and a Fe-S cluster [General function prediction only];


Pssm-ID: 442577 [Multi-domain]  Cd Length: 445  Bit Score: 75.28  E-value: 2.29e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580366  42 PTPRVAIIGAGISGLVAATELLRAGVkDITLFEARdRRIGGRVWSQtFDPRYPHLIaEMGAMRFPSSETCLFYYLNKLDI 121
Cdd:COG3349    2 MPPRVVVVGGGLAGLAAAVELAEAGF-RVTLLEAR-PRLGGRARSF-PDPDTGLPI-DNGQHVLLGCYRNTLDLLRRIGA 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580366 122 ATTTSFPDPGVVDTElhyRGVRHIWSAGDPPPSLfsrvhEGWVALLnegylhnGVPLVAPRDITAMLKsHCFDKARKAWQ 201
Cdd:COG3349   78 ADNLVGPEPLQFPLP---GGRRWTLRAPRLPAPL-----HLLRALL-------RAPGLSLADRLALLR-LLTACRERRWR 141

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580366 202 AWLDA-FRDYsfysalvtmFTSNTPPGGVpWRRpddfeLFGSLGIgSGGFLPVYQAG---FTEILRLVINGYEDDQRLII 277
Cdd:COG3349  142 ELDDIsVADW---------LRRHGQSPRL-IRR-----LWEPLLL-AALNTPPEQASarlALTVLRETLLAGPAASDLLV 205

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 696580366 278 --GGISTL----AERLVSQKIGDTRLSEhicfnEVKRIYKEDGEIK-LVSGKGQTHTFDRVIV 333
Cdd:COG3349  206 prGPLSELfvdpALAYLEARGGEVRLGT-----RVRALEFDGGRVTgLVLADGETVPADAVVL 263
COG1233 COG1233
Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and ...
 43-542 1.42e-12

Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440846 [Multi-domain]  Cd Length: 491  Bit Score: 69.88  E-value: 1.42e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580366  43 TPRVAIIGAGISGLVAATELLRAGvKDITLFEARDrRIGGRV--WSQ---TFDpRYPHLIaemgAMRFPSSEtcLFYYLN 117
Cdd:COG1233    3 MYDVVVIGAGIGGLAAAALLARAG-YRVTVLEKND-TPGGRArtFERpgfRFD-VGPSVL----TMPGVLER--LFRELG 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580366 118 KLDiatttsfpdpgvvdtELHYRgvrhiwsagdpPPSLFSRVHegwvallnegyLHNGVPLVAPRDITAMLKSHC--FDK 195
Cdd:COG1233   74 LED---------------YLELV-----------PLDPAYRVP-----------FPDGRALDLPRDLERTAAELErlFPG 116

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580366 196 ARKAWQAWLDAFRDysFYSALVTMFTSNTPPGGVPWRRPDDFELFGSLGIGSGG-----------------FLPVY---- 254
Cdd:COG1233  117 DAEAYRRFLAELRR--LYDALLEDLLYRPLLSLRDLLRPLALARLLRLLLRSLRdllrryfkdprlrallaGQALYlgls 194

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580366 255 --QAGFTEILrLVINGYEDDQRLIIGGISTLAERLVSqkigdtRLSEH---ICFN-EVKRIYKEDGEIKLVS-GKGQTHT 327
Cdd:COG1233  195 pdRTPALYAL-IAYLEYAGGVWYPKGGMGALADALAR------LAEELggeIRTGaEVERILVEGGRATGVRlADGEEIR 267

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580366 328 FDRVIVTSSTRT--MQIVhcltgDETFLEHDISRAVKETHLTGSS-KLFMLTRNKFwlnDSLPV-TIQSDGFIRGVYCLD 403
Cdd:COG1233  268 ADAVVSNADPAHtyLRLL-----GEEALPARYRRRLERFRYSPSAfKLYLGLDGPL---PGLAHhTIHLSEDYEAAFDDI 339

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580366 404 YEPDNPDGPGVVLLSYTWEDDA-----HKLLSI------------PDKKQRC-QYLVDDLAKINPEFARHLIpadgdYER 465
Cdd:COG1233  340 FRGRLPEDPSLYVSIPSLTDPSlapegKHTLWVlvpvpygledawDELKEEYaERILARLERYAPGLRDRIV-----ARE 414

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580366 466 YVLHHDWlvdpysagAFKLNYPGEDVYS------QRLFFQFKNANTPEKdtGLYLAGCGCsFTGGWIEGAMQTALNSACA 539
Cdd:COG1233  415 VLTPLDF--------ERYLNLVGGAIYGgahtldQSAFFRPSNYRTPIP--GLYLVGAST-HPGGGVPGVLISGRLAARR 483


                 ...
gi 696580366 540 VIR 542
Cdd:COG1233  484 ILK 486
HemY COG1232
Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen ...
 44-334 3.73e-12

Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen oxidase HemY/PPOX is part of the Pathway/BioSystem: Heme biosynthesis


Pssm-ID: 440845 [Multi-domain]  Cd Length: 443  Bit Score: 68.32  E-value: 3.73e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580366  44 PRVAIIGAGISGLVAATELLRAGVkDITLFEARDrRIGGRVWSQTFDP----RYPH-----------LIAEMG---AMRF 105
Cdd:COG1232    2 KRVAVIGGGIAGLTAAYRLAKAGH-EVTVLEASD-RVGGLIRTVEVDGfridRGPHsfltrdpevleLLRELGlgdELVW 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580366 106 PSSETCLFYYLNKL--------DIATTTSFPDPGVVDTELHYRGVRhiwSAGDPPPSLfsrvhEGWV-ALLNEGYLHNGV 176
Cdd:COG1232   80 PNTRKSYIYYGGKLhplpqgplALLRSPLLSLAGKLRALLELLAPR---RPPGEDESL-----AEFVrRRFGREVYERLV 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580366 177 -PLVA------PRDITamlkshcfdkARKAWQAWLDAFRDYsfYSALVTMFTS--NTPPGGVpwrrpddfelFGSLgigs 247
Cdd:COG1232  152 ePLLEgvyagdPDELS----------ADWAFPRLKRLELEH--GSLIKGALALrkGAKAGEV----------FGYL---- 205

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580366 248 ggflpvyqagfteilrlvingyeddqrliIGGISTLAERLVsQKIGDtrlsEHICFN-EVKRIYKEDGEIKLVSGKGQTH 326
Cdd:COG1232  206 -----------------------------RGGLGTLVEALA-EALEA----GEIRLGtRVTAIEREGGGWRVTTSDGETI 251


                 ....*...
gi 696580366 327 TFDRVIVT 334
Cdd:COG1232  252 EADAVVSA 259
PRK07233 PRK07233
hypothetical protein; Provisional
 45-454 1.82e-10

hypothetical protein; Provisional


Pssm-ID: 235977 [Multi-domain]  Cd Length: 434  Bit Score: 62.98  E-value: 1.82e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580366  45 RVAIIGAGISGLVAATELLRAGvKDITLFEARDrRIGGRVWSQTFD----PRYPH-----------LIAEMG---AMRFP 106
Cdd:PRK07233   1 KIAIVGGGIAGLAAAYRLAKRG-HEVTVFEADD-QLGGLAASFEFGglpiERFYHhifksdealleLLDELGledKLRWR 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580366 107 SSETClFYYLNKL-DIATTTSFpdpgvvdteLHYrgvrhiwsagdPPPSLFSRVHEGWVALLNeGYLHNGVPLvapRDIT 185
Cdd:PRK07233  79 ETKTG-YYVDGKLyPLGTPLEL---------LRF-----------PHLSLIDKFRLGLLTLLA-RRIKDWRAL---DKVP 133

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580366 186 AM--LKSHCFDKA-RKAWQAWLDA-FRDYS-------FYSALVtmFTSNtppggvpwRRPDdfelfgslgigsggflpvy 254
Cdd:PRK07233 134 AEewLRRWSGEGVyEVFWEPLLESkFGDYAddvsaawLWSRIK--RRGN--------RRYS------------------- 184

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580366 255 qaGFTEILrlvinGYEDdqrliiGGISTLAERLVsQKIGdtRLSEHICFN-EVKRIYKEDGEIKLVSGKGQTHTFDRVIV 333
Cdd:PRK07233 185 --LFGEKL-----GYLE------GGFATLIDALA-EAIE--ARGGEIRLGtPVTSVVIDGGGVTGVEVDGEEEDFDAVIS 248

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580366 334 TSSTrtmQIVHCLTGDETFLEHDISRAVKethLTGSSKLFMLTR----NKFWLN---DSLPVT--IQSDGFIrgvycldy 404
Cdd:PRK07233 249 TAPP---PILARLVPDLPADVLARLRRID---YQGVVCMVLKLRrpltDYYWLNindPGAPFGgvIEHTNLV-------- 314

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|...
gi 696580366 405 EPDNPDGPGVVLL-SYTweDDAHKLLSIPDK--KQRCqylVDDLAKINPEFAR 454
Cdd:PRK07233 315 PPERYGGEHLVYLpKYL--PGDHPLWQMSDEelLDRF---LSYLRKMFPDFDR 362
PLN02676 PLN02676
polyamine oxidase
 40-102 3.14e-10

polyamine oxidase


Pssm-ID: 215362 [Multi-domain]  Cd Length: 487  Bit Score: 62.42  E-value: 3.14e-10
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 696580366  40 GIPTPRVAIIGAGISGLVAATELLRAGVKDITLFEARDrRIGGRVWSQTFdpryPHLIAEMGA 102
Cdd:PLN02676  23 AKPSPSVIIVGAGMSGISAAKTLSEAGIEDILILEATD-RIGGRMRKANF----AGVSVELGA 80
COG3380 COG3380
Predicted NAD/FAD-dependent oxidoreductase [General function prediction only];
42-84 4.51e-10

Predicted NAD/FAD-dependent oxidoreductase [General function prediction only];


Pssm-ID: 442607 [Multi-domain]  Cd Length: 331  Bit Score: 61.43  E-value: 4.51e-10
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|...
gi 696580366  42 PTPRVAIIGAGISGLVAATELLRAGVkDITLFEaRDRRIGGRV 84
Cdd:COG3380    2 SMPDIAIIGAGIAGLAAARALQDAGH-EVTVFE-KSRGVGGRM 42
NAD_binding_8 pfam13450
NAD(P)-binding Rossmann-like domain;
48-119 7.29e-09

NAD(P)-binding Rossmann-like domain;


Pssm-ID: 433218 [Multi-domain]  Cd Length: 67  Bit Score: 52.15  E-value: 7.29e-09
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 696580366   48 IIGAGISGLVAATELLRAGvKDITLFEARDrRIGGRVwsqtFDPRYPHLIAEMGAMRF-PSSETCLFYYLNKL 119
Cdd:pfam13450   1 IVGAGLAGLVAAALLAKRG-FRVLVLEKRD-RLGGNA----YSYRVPGYVFDYGAHIFhGSDEPNVRDLLDEL 67
GltD COG0493
NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport ...
 30-82 2.04e-08

NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport and metabolism, General function prediction only]; NADPH-dependent glutamate synthase beta chain or related oxidoreductase is part of the Pathway/BioSystem: Glutamine biosynthesis


Pssm-ID: 440259 [Multi-domain]  Cd Length: 434  Bit Score: 56.68  E-value: 2.04e-08
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 696580366  30 AEGRIGYFPPGIPT-PRVAIIGAGISGLVAATELLRAGVkDITLFEARDrRIGG 82
Cdd:COG0493  107 EEGWVKPPPPAPRTgKKVAVVGSGPAGLAAAYQLARAGH-EVTVFEALD-KPGG 158
PRK11749 PRK11749
dihydropyrimidine dehydrogenase subunit A; Provisional
 37-82 3.28e-08

dihydropyrimidine dehydrogenase subunit A; Provisional


Pssm-ID: 236967 [Multi-domain]  Cd Length: 457  Bit Score: 55.96  E-value: 3.28e-08
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 696580366  37 FPPGIPTP-RVAIIGAGISGLVAATELLRAGVkDITLFEARDrRIGG 82
Cdd:PRK11749 133 FKRAPKTGkKVAVIGAGPAGLTAAHRLARKGY-DVTIFEARD-KAGG 177
CzcO COG2072
Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ...
 38-106 4.06e-08

Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism];


Pssm-ID: 441675 [Multi-domain]  Cd Length: 414  Bit Score: 55.64  E-value: 4.06e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 696580366  38 PPGIPTPRVAIIGAGISGLVAATELLRAGVkDITLFEARDrRIGGrVWsqtFDPRYP--HLIAEMGAMRFP 106
Cdd:COG2072    1 TAATEHVDVVVIGAGQAGLAAAYHLRRAGI-DFVVLEKAD-DVGG-TW---RDNRYPglRLDTPSHLYSLP 65
gltD PRK12810
glutamate synthase subunit beta; Reviewed
 30-82 4.91e-08

glutamate synthase subunit beta; Reviewed


Pssm-ID: 237213 [Multi-domain]  Cd Length: 471  Bit Score: 55.56  E-value: 4.91e-08
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 696580366  30 AEGRIGYFPPGIPT-PRVAIIGAGISGLVAATELLRAGVkDITLFEARDrRIGG 82
Cdd:PRK12810 129 EEGWVKPDPPVKRTgKKVAVVGSGPAGLAAADQLARAGH-KVTVFERAD-RIGG 180
PRK11883 PRK11883
protoporphyrinogen oxidase; Reviewed
 44-101 2.10e-07

protoporphyrinogen oxidase; Reviewed


Pssm-ID: 237009 [Multi-domain]  Cd Length: 451  Bit Score: 53.31  E-value: 2.10e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 696580366  44 PRVAIIGAGISGLVAATELLRAGVK-DITLFEARDrRIGGRVWSQTFD---------------PRYPHLIAEMG 101
Cdd:PRK11883   1 KKVAIIGGGITGLSAAYRLHKKGPDaDITLLEASD-RLGGKIQTVRKDgfpielgpesflarkPSAPALVKELG 73
Ppro0129 COG2907
Predicted flavin-containing amine oxidase [General function prediction only];
44-156 2.87e-07

Predicted flavin-containing amine oxidase [General function prediction only];


Pssm-ID: 442151 [Multi-domain]  Cd Length: 423  Bit Score: 52.81  E-value: 2.87e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580366  44 PRVAIIGAGISGLVAATELLRAgvKDITLFEArDRRIGG--------------------RVwsqtFDPR-YPHLIAemga 102
Cdd:COG2907    4 MRIAVIGSGISGLTAAWLLSRR--HDVTLFEA-NDRLGGhthtvdvdldgrtvpvdtgfIV----FNERtYPNLTA---- 72

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 696580366 103 mrfpssetcLFyylNKLDIAT---TTSFpdpGV--VDTELHYrgvrhiwsAGDPPPSLF 156
Cdd:COG2907   73 ---------LF---AELGVPTqpsDMSF---SVslDGGGLEY--------AGSNLNGLF 108
PLN02487 PLN02487
zeta-carotene desaturase
 35-101 7.07e-07

zeta-carotene desaturase


Pssm-ID: 215268 [Multi-domain]  Cd Length: 569  Bit Score: 52.11  E-value: 7.07e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 696580366  35 GYFPPGIPTPR-----VAIIGAGISGLVAATELLRAGvKDITLFEARdRRIGGRVWSQTfDPRYPHLiaEMG 101
Cdd:PLN02487  62 GLFPPEPEAYKgpklkVAIIGAGLAGMSTAVELLDQG-HEVDIYESR-PFIGGKVGSFV-DKNGNHI--EMG 128
PLN02576 PLN02576
protoporphyrinogen oxidase
 45-86 7.54e-07

protoporphyrinogen oxidase


Pssm-ID: 215314 [Multi-domain]  Cd Length: 496  Bit Score: 51.94  E-value: 7.54e-07
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|..
gi 696580366  45 RVAIIGAGISGLVAATELLRAGVKDITLFEARDrRIGGRVWS 86
Cdd:PLN02576  14 DVAVVGAGVSGLAAAYALASKHGVNVLVTEARD-RVGGNITS 54
PLN02268 PLN02268
probable polyamine oxidase
 44-84 1.10e-06

probable polyamine oxidase


Pssm-ID: 177909 [Multi-domain]  Cd Length: 435  Bit Score: 51.23  E-value: 1.10e-06
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 696580366  44 PRVAIIGAGISGLVAATELLRAGVKdITLFEARDrRIGGRV 84
Cdd:PLN02268   1 PSVIVIGGGIAGIAAARALHDASFK-VTLLESRD-RIGGRV 39
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
 42-84 4.08e-06

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 48.78  E-value: 4.08e-06
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....
gi 696580366  42 PTPRVAIIGAGISGLVAATELLRAGVkDITLFEARDR-RIGGRV 84
Cdd:COG0654    2 MRTDVLIVGGGPAGLALALALARAGI-RVTVVERAPPpRPDGRG 44
PLN03000 PLN03000
amine oxidase
 37-101 5.77e-06

amine oxidase


Pssm-ID: 178578 [Multi-domain]  Cd Length: 881  Bit Score: 49.25  E-value: 5.77e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 696580366  37 FPPGIPTPRVAIIGAGISGLVAATELLRAGVKdITLFEARdRRIGGRVWSQTFDPRYPHLIAEMG 101
Cdd:PLN03000 178 FPAQSSKSSVVIVGAGLSGLAAARQLMRFGFK-VTVLEGR-KRPGGRVYTKKMEANRVGAAADLG 240
PLN02568 PLN02568
polyamine oxidase
 44-102 6.86e-06

polyamine oxidase


Pssm-ID: 215308 [Multi-domain]  Cd Length: 539  Bit Score: 48.67  E-value: 6.86e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 696580366  44 PRVAIIGAGISGLVAATELLRAGVK----DITLFEARDrRIGGRVWSQTFDpryPHLIaEMGA 102
Cdd:PLN02568   6 PRIVIIGAGMAGLTAANKLYTSSAAndmfELTVVEGGD-RIGGRINTSEFG---GERI-EMGA 63
YdhS COG4529
Uncharacterized NAD(P)/FAD-binding protein YdhS [General function prediction only];
42-102 6.98e-06

Uncharacterized NAD(P)/FAD-binding protein YdhS [General function prediction only];


Pssm-ID: 443597 [Multi-domain]  Cd Length: 466  Bit Score: 48.80  E-value: 6.98e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 696580366  42 PTPRVAIIGAGISGLVAATELLRAGVK--DITLFEaRDRRIG-GRVWSQTfDPRypHLI----AEMGA 102
Cdd:COG4529    4 ARKRIAIIGGGASGTALAIHLLRRAPEplRITLFE-PRPELGrGVAYSTD-SPE--HLLnvpaGRMSA 67
mnmC PRK01747
bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent ...
 36-78 1.44e-05

bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC;


Pssm-ID: 234978 [Multi-domain]  Cd Length: 662  Bit Score: 47.92  E-value: 1.44e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....
gi 696580366  36 YFPPGIPTPR-VAIIGAGISGLVAATELLRAGVKdITLFEARDR 78
Cdd:PRK01747 252 FARPGSPKARdAAIIGGGIAGAALALALARRGWQ-VTLYEADEA 294
NAD_binding_9 pfam13454
FAD-NAD(P)-binding;
47-97 4.59e-05

FAD-NAD(P)-binding;


Pssm-ID: 433222 [Multi-domain]  Cd Length: 155  Bit Score: 43.81  E-value: 4.59e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 696580366   47 AIIGAGISGLVAATELLRAGVK---DITLFEarDRRIG-GRVWSQTFDPRypHLI 97
Cdd:pfam13454   1 AIVGGGPSGLALLERLLARAPKrplEITLFD--PSPPGaGGVYRTDQSPE--HLL 51
PRK07208 PRK07208
hypothetical protein; Provisional
 42-82 4.81e-05

hypothetical protein; Provisional


Pssm-ID: 235967 [Multi-domain]  Cd Length: 479  Bit Score: 46.04  E-value: 4.81e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 696580366  42 PTPRVAIIGAGISGLVAATELLRAGVkDITLFEArDRRIGG 82
Cdd:PRK07208   3 NKKSVVIIGAGPAGLTAAYELLKRGY-PVTVLEA-DPVVGG 41
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
43-98 1.01e-04

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 44.90  E-value: 1.01e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 696580366  43 TPRVAIIGAGISGLVAATELLRAGVkDITLFEARD------RRIGGRVWSQTFDPRYPHLIA 98
Cdd:COG0665    2 TADVVVIGGGIAGLSTAYHLARRGL-DVTVLERGRpgsgasGRNAGQLRPGLAALADRALVR 62
PLN02328 PLN02328
lysine-specific histone demethylase 1 homolog
 31-84 1.27e-04

lysine-specific histone demethylase 1 homolog


Pssm-ID: 215187 [Multi-domain]  Cd Length: 808  Bit Score: 44.98  E-value: 1.27e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 696580366  31 EGRIGYFPpGIPTPRVAIIGAGISGLVAATELLRAGVKDITLfEARDRRiGGRV 84
Cdd:PLN02328 227 EAQLRSFE-GVEPANVVVVGAGLAGLVAARQLLSMGFKVVVL-EGRARP-GGRV 277
DAO pfam01266
FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: ...
 45-78 1.29e-04

FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1.


Pssm-ID: 426168 [Multi-domain]  Cd Length: 339  Bit Score: 44.31  E-value: 1.29e-04
                          10        20        30
                  ....*....|....*....|....*....|....
gi 696580366   45 RVAIIGAGISGLVAATELLRAGVkDITLFEARDR 78
Cdd:pfam01266   1 DVVVIGGGIVGLSTAYELARRGL-SVTLLERGDD 33
COG3573 COG3573
Predicted oxidoreductase [General function prediction only];
46-85 2.22e-04

Predicted oxidoreductase [General function prediction only];


Pssm-ID: 442794 [Multi-domain]  Cd Length: 551  Bit Score: 44.01  E-value: 2.22e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|
gi 696580366  46 VAIIGAGISGLVAATELLRAGVKDITLFEARDRRIGGRVW 85
Cdd:COG3573    8 VIVVGAGLAGLVAAAELADAGRRVLLLDQEPEANLGGQAF 47
PLN02976 PLN02976
amine oxidase
 45-86 2.50e-04

amine oxidase


Pssm-ID: 215527 [Multi-domain]  Cd Length: 1713  Bit Score: 44.09  E-value: 2.50e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 696580366   45 RVAIIGAGISGLVAATELLRAGVKdITLFEARDRrIGGRVWS 86
Cdd:PLN02976  695 KIIVVGAGPAGLTAARHLQRQGFS-VTVLEARSR-IGGRVYT 734
HdrA COG1148
Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];
43-89 2.52e-04

Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];


Pssm-ID: 440762 [Multi-domain]  Cd Length: 563  Bit Score: 43.70  E-value: 2.52e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 696580366  43 TPRVAIIGAGISGLVAATELLRAGVKdITLFEaRDRRIGGRV--WSQTF 89
Cdd:COG1148  140 NKRALVIGGGIAGMTAALELAEQGYE-VYLVE-KEPELGGRAaqLHKTF 186
proto_IX_ox TIGR00562
protoporphyrinogen oxidase; This enzyme oxidizes protoporphyrinogen IX to protoporphyrin IX, a ...
 42-90 2.61e-04

protoporphyrinogen oxidase; This enzyme oxidizes protoporphyrinogen IX to protoporphyrin IX, a precursor of heme and chlorophyll. Bacillus subtilis HemY also has coproporphyrinogen III to coproporphyrin III oxidase activity in a heterologous expression system, although the role for this activity in vivo is unclear. This protein is a flavoprotein and has a beta-alpha-beta dinucleotide binding motif near the amino end. [Biosynthesis of cofactors, prosthetic groups, and carriers, Heme, porphyrin, and cobalamin]


Pssm-ID: 213540 [Multi-domain]  Cd Length: 462  Bit Score: 43.67  E-value: 2.61e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 696580366   42 PTPRVAIIGAGISGLVAA----TELLRAGVkDITLFEARDrRIGGrvWSQTFD 90
Cdd:TIGR00562   1 GKKHVVIIGGGISGLCAAyyleKEIPELPV-ELTLVEASD-RVGG--KIQTVK 49
PRK12834 PRK12834
putative FAD-binding dehydrogenase; Reviewed
 46-86 4.18e-04

putative FAD-binding dehydrogenase; Reviewed


Pssm-ID: 183782 [Multi-domain]  Cd Length: 549  Bit Score: 42.96  E-value: 4.18e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|..
gi 696580366  46 VAIIGAGISGLVAATELLRAGVKDITLFEARDRRIGGRV-WS 86
Cdd:PRK12834   7 VIVVGAGLAGLVAAAELADAGKRVLLLDQENEANLGGQAfWS 48
PRK12814 PRK12814
putative NADPH-dependent glutamate synthase small subunit; Provisional
 35-77 7.49e-04

putative NADPH-dependent glutamate synthase small subunit; Provisional


Pssm-ID: 139246 [Multi-domain]  Cd Length: 652  Bit Score: 42.41  E-value: 7.49e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 696580366  35 GYFPPGIPTP--RVAIIGAGISGLVAATELLRAGvKDITLFEARD 77
Cdd:PRK12814 183 RYIPERAPKSgkKVAIIGAGPAGLTAAYYLLRKG-HDVTIFDANE 226
Pyr_redox_2 pfam07992
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 44-85 1.02e-03

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 400379 [Multi-domain]  Cd Length: 301  Bit Score: 41.53  E-value: 1.02e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 696580366   44 PRVAIIGAGISGLVAATELLRAGVKdITLFEARDRRIGGRVW 85
Cdd:pfam07992   1 YDVVVIGGGPAGLAAALTLAQLGGK-VTLIEDEGTCPYGGCV 41
Pyr_redox pfam00070
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 45-78 1.51e-03

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 425450 [Multi-domain]  Cd Length: 80  Bit Score: 37.57  E-value: 1.51e-03
                          10        20        30
                  ....*....|....*....|....*....|....
gi 696580366   45 RVAIIGAGISGLVAATELLRAGvKDITLFEARDR 78
Cdd:pfam00070   1 RVVVVGGGYIGLELAGALARLG-SKVTVVERRDR 33
PRK12771 PRK12771
putative glutamate synthase (NADPH) small subunit; Provisional
 38-82 1.52e-03

putative glutamate synthase (NADPH) small subunit; Provisional


Pssm-ID: 237198 [Multi-domain]  Cd Length: 564  Bit Score: 41.40  E-value: 1.52e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 696580366  38 PPGIPT-PRVAIIGAGISGLVAATELLRAGvKDITLFEARDrRIGG 82
Cdd:PRK12771 131 APAPDTgKRVAVIGGGPAGLSAAYHLRRMG-HAVTIFEAGP-KLGG 174
LhgO COG0579
L-2-hydroxyglutarate oxidase LhgO [Carbohydrate transport and metabolism];
46-78 1.97e-03

L-2-hydroxyglutarate oxidase LhgO [Carbohydrate transport and metabolism];


Pssm-ID: 440344 [Multi-domain]  Cd Length: 418  Bit Score: 40.90  E-value: 1.97e-03
                         10        20        30
                 ....*....|....*....|....*....|...
gi 696580366  46 VAIIGAGISGLVAATELLRAGVKDITLFEARDR 78
Cdd:COG0579    7 VVIIGAGIVGLALARELSRYEDLKVLVLEKEDD 39
PLN02172 PLN02172
flavin-containing monooxygenase FMO GS-OX
 41-88 3.37e-03

flavin-containing monooxygenase FMO GS-OX


Pssm-ID: 215116 [Multi-domain]  Cd Length: 461  Bit Score: 40.23  E-value: 3.37e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 696580366  41 IPTPRVAIIGAGISGLVAATELLRAGvKDITLFEaRDRRIGGrVWSQT 88
Cdd:PLN02172   8 INSQHVAVIGAGAAGLVAARELRREG-HTVVVFE-REKQVGG-LWVYT 52
PRK05335 PRK05335
tRNA (uracil-5-)-methyltransferase Gid; Reviewed
 43-79 5.86e-03

tRNA (uracil-5-)-methyltransferase Gid; Reviewed


Pssm-ID: 235416  Cd Length: 436  Bit Score: 39.36  E-value: 5.86e-03
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 696580366  43 TPRVAIIGAGISGLVAATELLRAGVKdITLFEARDRR 79
Cdd:PRK05335   2 MKPVNVIGAGLAGSEAAWQLAKRGVP-VELYEMRPVK 37
AlaDh_PNT_C smart01002
Alanine dehydrogenase/PNT, C-terminal domain; Alanine dehydrogenase catalyzes the ...
 38-99 5.87e-03

Alanine dehydrogenase/PNT, C-terminal domain; Alanine dehydrogenase catalyzes the NAD-dependent reversible reductive amination of pyruvate into alanine.


Pssm-ID: 214966 [Multi-domain]  Cd Length: 149  Bit Score: 37.49  E-value: 5.87e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 696580366    38 PPGIPTPRVAIIGAGISGLVAATELLRAGVkDITLF---EARDRRI----GGRVWSQTfdpRYPHLIAE 99
Cdd:smart01002  15 AGGVPPAKVVVIGAGVVGLGAAATAKGLGA-EVTVLdvrPARLRQLesllGARFTTLY---SQAELLEE 79
FAD_binding_2 pfam00890
FAD binding domain; This family includes members that bind FAD. This family includes the ...
 46-87 7.48e-03

FAD binding domain; This family includes members that bind FAD. This family includes the flavoprotein subunits from succinate and fumarate dehydrogenase, aspartate oxidase and the alpha subunit of adenylylsulphate reductase.


Pssm-ID: 395718 [Multi-domain]  Cd Length: 398  Bit Score: 38.81  E-value: 7.48e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 696580366   46 VAIIGAGISGLVAATELLRAGvKDITLFEARDRRIGGRVWSQ 87
Cdd:pfam00890   2 VLVIGGGLAGLAAALAAAEAG-LKVAVVEKGQPFGGATAWSS 42
Ald COG0686
Alanine dehydrogenase (includes sporulation protein SpoVN) [Amino acid transport and ...
 39-106 7.53e-03

Alanine dehydrogenase (includes sporulation protein SpoVN) [Amino acid transport and metabolism]; Alanine dehydrogenase (includes sporulation protein SpoVN) is part of the Pathway/BioSystem: Urea cycle


Pssm-ID: 440450 [Multi-domain]  Cd Length: 372  Bit Score: 38.84  E-value: 7.53e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 696580366  39 PGIPTPRVAIIGAGISGLVAA-TEL-LRAGVK--DITLFEAR--DRRIGGRVWSQTFDpryPHLIAE--------MGAMR 104
Cdd:COG0686  164 PGVPPAKVVILGGGVVGTNAArMALgLGADVTvlDINLDRLRrlDDIFGGRVTTLYSN---PANIEEalkeadlvIGAVL 240


                 ..
gi 696580366 105 FP 106
Cdd:COG0686  241 IP 242
PRK06753 PRK06753
hypothetical protein; Provisional
 45-76 8.11e-03

hypothetical protein; Provisional


Pssm-ID: 168661 [Multi-domain]  Cd Length: 373  Bit Score: 38.90  E-value: 8.11e-03
                         10        20        30
                 ....*....|....*....|....*....|..
gi 696580366  45 RVAIIGAGISGLVAATELLRAGVkDITLFEAR 76
Cdd:PRK06753   2 KIAIIGAGIGGLTAAALLQEQGH-EVKVFEKN 32
PRK06847 PRK06847
hypothetical protein; Provisional
 45-81 9.68e-03

hypothetical protein; Provisional


Pssm-ID: 235874 [Multi-domain]  Cd Length: 375  Bit Score: 38.32  E-value: 9.68e-03
                         10        20        30
                 ....*....|....*....|....*....|....*....
gi 696580366  45 RVAIIGAGISGLVAATELLRAGVkDITLFEARD--RRIG 81
Cdd:PRK06847   6 KVLIVGGGIGGLSAAIALRRAGI-AVDLVEIDPewRVYG 43
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH