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Conserved domains on  [gi|71896147|ref|NP_001026759|]
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6-phosphogluconolactonase [Gallus gallus]

Protein Classification

6-phosphogluconolactonase( domain architecture ID 10105380)

6-phosphogluconolactonase catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate, which is the the second step of the oxidative phase of the pentose phosphate pathway

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
6PGL cd01400
6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the ...
 12-232 2.61e-87

6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the oxidative phase of the pentose phosphate pathway, the hydrolyzation of 6-phosphoglucono-1,5-lactone (delta form) to 6-phosphogluconate. 6PGL is thought to guard against the accumulation of the delta form of the lactone, which may be toxic through its reaction with endogenous cellular nucleophiles.


:

Pssm-ID: 238694 [Multi-domain]  Cd Length: 219  Bit Score: 258.26  E-value: 2.61e-87
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71896147  12 QELGSALAQLVVQRAAGS---DGRFSLGLSGGSLVGLLARELplaattgAATGAGPW---LVAFCDERLVPPEHPESTFG 85
Cdd:cd01400   1 EALAEALADRIAEALAAAiakRGRFSLALSGGSTPKPLYELL-------AAAPALDWskvHVFLGDERCVPPDDPDSNYR 73

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71896147  86 AYSAQLLPWLPAPAPTVLAVAPGLSPNAAAADYAERLREAFqgDAVPVFDLLLLGVGPDGHTCSLFPNHP-LLQEKEKIV 164
Cdd:cd01400  74 LAREALLSHVAIPAANIHPIPTELGPEDAAAAYEKELRALF--GGVPPFDLVLLGMGPDGHTASLFPGHPaLLEETDRLV 151

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 71896147 165 AAITDSPKPPPQRITLTLPVLNAARTVVFVATGEGKAAVLKRILEGNEENPLPAARVRPHTGQLLWFL 232
Cdd:cd01400 152 VAVTDSPKPPPERITLTLPVLNNARRVVFLVTGAEKAEALKRALAGPDPEELPAARVLPRPGEVLWFL 219
 
Name Accession Description Interval E-value
6PGL cd01400
6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the ...
 12-232 2.61e-87

6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the oxidative phase of the pentose phosphate pathway, the hydrolyzation of 6-phosphoglucono-1,5-lactone (delta form) to 6-phosphogluconate. 6PGL is thought to guard against the accumulation of the delta form of the lactone, which may be toxic through its reaction with endogenous cellular nucleophiles.


Pssm-ID: 238694 [Multi-domain]  Cd Length: 219  Bit Score: 258.26  E-value: 2.61e-87
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71896147  12 QELGSALAQLVVQRAAGS---DGRFSLGLSGGSLVGLLARELplaattgAATGAGPW---LVAFCDERLVPPEHPESTFG 85
Cdd:cd01400   1 EALAEALADRIAEALAAAiakRGRFSLALSGGSTPKPLYELL-------AAAPALDWskvHVFLGDERCVPPDDPDSNYR 73

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71896147  86 AYSAQLLPWLPAPAPTVLAVAPGLSPNAAAADYAERLREAFqgDAVPVFDLLLLGVGPDGHTCSLFPNHP-LLQEKEKIV 164
Cdd:cd01400  74 LAREALLSHVAIPAANIHPIPTELGPEDAAAAYEKELRALF--GGVPPFDLVLLGMGPDGHTASLFPGHPaLLEETDRLV 151

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 71896147 165 AAITDSPKPPPQRITLTLPVLNAARTVVFVATGEGKAAVLKRILEGNEENPLPAARVRPHTGQLLWFL 232
Cdd:cd01400 152 VAVTDSPKPPPERITLTLPVLNNARRVVFLVTGAEKAEALKRALAGPDPEELPAARVLPRPGEVLWFL 219
Glucosamine_iso pfam01182
Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase;
9-230 4.99e-86

Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase;


Pssm-ID: 460101 [Multi-domain]  Cd Length: 222  Bit Score: 254.85  E-value: 4.99e-86
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71896147     9 PSPQELGSALAQLVVQRAA---GSDGRFSLGLSGGSLVGLLARELplaattGAATGAGPW---LVAFCDERLVPPEHPES 82
Cdd:pfam01182   1 PDAEALAQALAERLAEALEaalAERGRFTLALSGGSTPKPLYELL------AAAPARLDWsrvHVFWGDERCVPPDDPDS 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71896147    83 TFGAYSAQLLPWLPAPAPTVLAV-APGLSPNAAAADYAERLREAFQGDAVPVFDLLLLGVGPDGHTCSLFPNHPLLQEKE 161
Cdd:pfam01182  75 NYGMAREALLSHVPIPASNVHPIpASAADPEEAAAAYEAELRELLPDLELPVFDLVLLGMGPDGHTASLFPGSPALEETD 154

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 71896147   162 KIVAAITDSPKPPPQRITLTLPVLNAARTVVFVATGEGKAAVLKRILEGNEEnPLPAARVRPHTGQLLW 230
Cdd:pfam01182 155 RLVVAVTDSPKPPPERITLTLPVLNAARRVWFLVTGAGKADALRRALAGDPD-PLPAALVRPGAGETVW 222
pgl TIGR01198
6-phosphogluconolactonase; This enzyme of the pentose phosphate pathway is often found as a ...
 7-240 1.18e-78

6-phosphogluconolactonase; This enzyme of the pentose phosphate pathway is often found as a part of a multifunctional protein with [Energy metabolism, Pentose phosphate pathway]


Pssm-ID: 273494 [Multi-domain]  Cd Length: 233  Bit Score: 236.89  E-value: 1.18e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71896147     7 VFPSPQELGSALAQLVVQRAAG---SDGRFSLGLSGGSLVGLLARELPlaattgaaTGAGPW---LVAFCDERLVPPEHP 80
Cdd:TIGR01198   1 VFSNSAELAEALAERIATKLQTalaERGQFSLALSGGRSPIALLEALA--------AQPLDWsriHLFLGDERYVPLDHA 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71896147    81 ESTFGAYSAQLLPWLPAPAPTVLAVAPGLS-PNAAAADYAERLREAFQGDAVPVFDLLLLGVGPDGHTCSLFPNHPLLQE 159
Cdd:TIGR01198  73 DSNTGLAREALLDRVAIPASNIHPMPTELSdIEEAAELYEQELAAAFQPIVFPVFDLLLLGMGPDGHTASLFPHTPALQE 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71896147   160 KEKIVAAITDSPKPPPQRITLTLPVLNAARTVVFVATGEGKAAVLKRILEGNEENPLPAARVRPHTGQLLWFLDEAAAKE 239
Cdd:TIGR01198 153 TERLVTVLTKSPKPPHERITLTLPAINAARKVFLLIAGEEKRNALAEALAVEAEPYPLPAAGVLHSGKTLWLLDYAAARK 232


                  .
gi 71896147   240 L 240
Cdd:TIGR01198 233 L 233
NagB COG0363
6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport ...
 4-241 2.28e-58

6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase is part of the Pathway/BioSystem: Pentose phosphate pathway


Pssm-ID: 440132 [Multi-domain]  Cd Length: 248  Bit Score: 185.36  E-value: 2.28e-58
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71896147   4 RISVFPSPQELGSALAQLVVQRAA---GSDGRFSLGLSGGSLVGLLARELplaaTTGAATGAGPW--LVAFC-DERL-VP 76
Cdd:COG0363   3 RVIIFPDAEELAAAAAERAAERIAeaiAEKGRAVLGLAGGSTPLGLYEEL----ARLHKEGGLDWsrVHVFNlDEYVgLP 78

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71896147  77 PEHPESTFGAYSAQLLPWLPAPAPTVLAVaPGLS--PNAAAADYAERLREAfqgdavPVFDLLLLGVGPDGHTCSLFPNH 154
Cdd:COG0363  79 PDHPQSNRRFMREALLDHVDIPPENIHIP-DGEAedPEAAAARYEALIAEA------GGIDLQLLGIGEDGHIAFNFPGS 151

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71896147 155 PLLQEKEKIVAA-----------ITDSPKPPPQRITLTLPVLNAARTVVFVATGEGKAAVLKRILEGNEENPLPAARVRP 223
Cdd:COG0363 152 PFLSETDRVVTLdestrqanarfFGSIPKVPPQAITLGIPTIMKAREILLLATGENKAEAVAAALEGPVTEEVPASILQG 231

                       250
                ....*....|....*...
gi 71896147 224 HtGQLLWFLDEAAAKELT 241
Cdd:COG0363 232 H-PNVTWFLDEAAASLLT 248
PLN02360 PLN02360
probable 6-phosphogluconolactonase
 3-240 3.40e-56

probable 6-phosphogluconolactonase


Pssm-ID: 166001 [Multi-domain]  Cd Length: 268  Bit Score: 180.82  E-value: 3.40e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71896147    3 GRISVFPSPQELGSALAQLVVQRAAGS---DGRFSLGLSGGSLVGLLAR--ELPLAATTGAATgagpWLVAFCDERLVPP 77
Cdd:PLN02360  11 GEIRVHENLDELSTDLAEYIAELSEASvkeRGVFAIALSGGSLISFMGKlcEAPYNKTVDWAK----WYIFWADERVVAK 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71896147   78 EHPESTFGAYSAQLLPWLPAPAPTVLAVAPGLSPNAAAADYAERLREAFQGDAV--------PVFDLLLLGVGPDGHTCS 149
Cdd:PLN02360  87 NHADSNYKLAKDGLLSKVPVVPSHVYSINDTVTAEEAATDYEFAIRQLVKTRTIgvsdisdcPKFDLILLGMGSDGHVAS 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71896147  150 LFPNHPLLQEKEKIVAAITDSPKPPPQRITLTLPVLNAARTVVFVATGEGKA-AV---LKRILEGNEENPLPAARVRPHT 225
Cdd:PLN02360 167 LFPNHPALEEKDDWVTFITDSPKPPPERITFTLPVINSASNVAVVATGESKAnAVhlaIDDVTEGPDAPSLPARMVQPTK 246

                        250
                 ....*....|....*
gi 71896147  226 GQLLWFLDEAAAKEL 240
Cdd:PLN02360 247 GKLVWFLDKPAASKL 261
 
Name Accession Description Interval E-value
6PGL cd01400
6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the ...
 12-232 2.61e-87

6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the oxidative phase of the pentose phosphate pathway, the hydrolyzation of 6-phosphoglucono-1,5-lactone (delta form) to 6-phosphogluconate. 6PGL is thought to guard against the accumulation of the delta form of the lactone, which may be toxic through its reaction with endogenous cellular nucleophiles.


Pssm-ID: 238694 [Multi-domain]  Cd Length: 219  Bit Score: 258.26  E-value: 2.61e-87
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71896147  12 QELGSALAQLVVQRAAGS---DGRFSLGLSGGSLVGLLARELplaattgAATGAGPW---LVAFCDERLVPPEHPESTFG 85
Cdd:cd01400   1 EALAEALADRIAEALAAAiakRGRFSLALSGGSTPKPLYELL-------AAAPALDWskvHVFLGDERCVPPDDPDSNYR 73

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71896147  86 AYSAQLLPWLPAPAPTVLAVAPGLSPNAAAADYAERLREAFqgDAVPVFDLLLLGVGPDGHTCSLFPNHP-LLQEKEKIV 164
Cdd:cd01400  74 LAREALLSHVAIPAANIHPIPTELGPEDAAAAYEKELRALF--GGVPPFDLVLLGMGPDGHTASLFPGHPaLLEETDRLV 151

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 71896147 165 AAITDSPKPPPQRITLTLPVLNAARTVVFVATGEGKAAVLKRILEGNEENPLPAARVRPHTGQLLWFL 232
Cdd:cd01400 152 VAVTDSPKPPPERITLTLPVLNNARRVVFLVTGAEKAEALKRALAGPDPEELPAARVLPRPGEVLWFL 219
Glucosamine_iso pfam01182
Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase;
9-230 4.99e-86

Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase;


Pssm-ID: 460101 [Multi-domain]  Cd Length: 222  Bit Score: 254.85  E-value: 4.99e-86
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71896147     9 PSPQELGSALAQLVVQRAA---GSDGRFSLGLSGGSLVGLLARELplaattGAATGAGPW---LVAFCDERLVPPEHPES 82
Cdd:pfam01182   1 PDAEALAQALAERLAEALEaalAERGRFTLALSGGSTPKPLYELL------AAAPARLDWsrvHVFWGDERCVPPDDPDS 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71896147    83 TFGAYSAQLLPWLPAPAPTVLAV-APGLSPNAAAADYAERLREAFQGDAVPVFDLLLLGVGPDGHTCSLFPNHPLLQEKE 161
Cdd:pfam01182  75 NYGMAREALLSHVPIPASNVHPIpASAADPEEAAAAYEAELRELLPDLELPVFDLVLLGMGPDGHTASLFPGSPALEETD 154

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 71896147   162 KIVAAITDSPKPPPQRITLTLPVLNAARTVVFVATGEGKAAVLKRILEGNEEnPLPAARVRPHTGQLLW 230
Cdd:pfam01182 155 RLVVAVTDSPKPPPERITLTLPVLNAARRVWFLVTGAGKADALRRALAGDPD-PLPAALVRPGAGETVW 222
pgl TIGR01198
6-phosphogluconolactonase; This enzyme of the pentose phosphate pathway is often found as a ...
 7-240 1.18e-78

6-phosphogluconolactonase; This enzyme of the pentose phosphate pathway is often found as a part of a multifunctional protein with [Energy metabolism, Pentose phosphate pathway]


Pssm-ID: 273494 [Multi-domain]  Cd Length: 233  Bit Score: 236.89  E-value: 1.18e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71896147     7 VFPSPQELGSALAQLVVQRAAG---SDGRFSLGLSGGSLVGLLARELPlaattgaaTGAGPW---LVAFCDERLVPPEHP 80
Cdd:TIGR01198   1 VFSNSAELAEALAERIATKLQTalaERGQFSLALSGGRSPIALLEALA--------AQPLDWsriHLFLGDERYVPLDHA 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71896147    81 ESTFGAYSAQLLPWLPAPAPTVLAVAPGLS-PNAAAADYAERLREAFQGDAVPVFDLLLLGVGPDGHTCSLFPNHPLLQE 159
Cdd:TIGR01198  73 DSNTGLAREALLDRVAIPASNIHPMPTELSdIEEAAELYEQELAAAFQPIVFPVFDLLLLGMGPDGHTASLFPHTPALQE 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71896147   160 KEKIVAAITDSPKPPPQRITLTLPVLNAARTVVFVATGEGKAAVLKRILEGNEENPLPAARVRPHTGQLLWFLDEAAAKE 239
Cdd:TIGR01198 153 TERLVTVLTKSPKPPHERITLTLPAINAARKVFLLIAGEEKRNALAEALAVEAEPYPLPAAGVLHSGKTLWLLDYAAARK 232


                  .
gi 71896147   240 L 240
Cdd:TIGR01198 233 L 233
NagB COG0363
6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport ...
 4-241 2.28e-58

6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase is part of the Pathway/BioSystem: Pentose phosphate pathway


Pssm-ID: 440132 [Multi-domain]  Cd Length: 248  Bit Score: 185.36  E-value: 2.28e-58
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71896147   4 RISVFPSPQELGSALAQLVVQRAA---GSDGRFSLGLSGGSLVGLLARELplaaTTGAATGAGPW--LVAFC-DERL-VP 76
Cdd:COG0363   3 RVIIFPDAEELAAAAAERAAERIAeaiAEKGRAVLGLAGGSTPLGLYEEL----ARLHKEGGLDWsrVHVFNlDEYVgLP 78

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71896147  77 PEHPESTFGAYSAQLLPWLPAPAPTVLAVaPGLS--PNAAAADYAERLREAfqgdavPVFDLLLLGVGPDGHTCSLFPNH 154
Cdd:COG0363  79 PDHPQSNRRFMREALLDHVDIPPENIHIP-DGEAedPEAAAARYEALIAEA------GGIDLQLLGIGEDGHIAFNFPGS 151

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71896147 155 PLLQEKEKIVAA-----------ITDSPKPPPQRITLTLPVLNAARTVVFVATGEGKAAVLKRILEGNEENPLPAARVRP 223
Cdd:COG0363 152 PFLSETDRVVTLdestrqanarfFGSIPKVPPQAITLGIPTIMKAREILLLATGENKAEAVAAALEGPVTEEVPASILQG 231

                       250
                ....*....|....*...
gi 71896147 224 HtGQLLWFLDEAAAKELT 241
Cdd:COG0363 232 H-PNVTWFLDEAAASLLT 248
PLN02360 PLN02360
probable 6-phosphogluconolactonase
 3-240 3.40e-56

probable 6-phosphogluconolactonase


Pssm-ID: 166001 [Multi-domain]  Cd Length: 268  Bit Score: 180.82  E-value: 3.40e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71896147    3 GRISVFPSPQELGSALAQLVVQRAAGS---DGRFSLGLSGGSLVGLLAR--ELPLAATTGAATgagpWLVAFCDERLVPP 77
Cdd:PLN02360  11 GEIRVHENLDELSTDLAEYIAELSEASvkeRGVFAIALSGGSLISFMGKlcEAPYNKTVDWAK----WYIFWADERVVAK 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71896147   78 EHPESTFGAYSAQLLPWLPAPAPTVLAVAPGLSPNAAAADYAERLREAFQGDAV--------PVFDLLLLGVGPDGHTCS 149
Cdd:PLN02360  87 NHADSNYKLAKDGLLSKVPVVPSHVYSINDTVTAEEAATDYEFAIRQLVKTRTIgvsdisdcPKFDLILLGMGSDGHVAS 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71896147  150 LFPNHPLLQEKEKIVAAITDSPKPPPQRITLTLPVLNAARTVVFVATGEGKA-AV---LKRILEGNEENPLPAARVRPHT 225
Cdd:PLN02360 167 LFPNHPALEEKDDWVTFITDSPKPPPERITFTLPVINSASNVAVVATGESKAnAVhlaIDDVTEGPDAPSLPARMVQPTK 246

                        250
                 ....*....|....*
gi 71896147  226 GQLLWFLDEAAAKEL 240
Cdd:PLN02360 247 GKLVWFLDKPAASKL 261
GlcN6P_deaminase cd01399
GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase ...
 111-240 3.84e-15

GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or deamination. It is the last step of the metabolic pathway of N-acetyl-D-glucosamine-6-phosphate (GlcNAc6P). GlcN6P deaminase is a hexameric enzyme that is allosterically activated by GlcNAc6P.


Pssm-ID: 238693 [Multi-domain]  Cd Length: 232  Bit Score: 72.13  E-value: 3.84e-15
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71896147 111 PNAAAADYAERLREAfqGdavPVfDLLLLGVGPDGHTCslF--PNHPL--------LQEKEKIVAA--ITDSPKPPPQRI 178
Cdd:cd01399 100 LEAECRRYEALIAEA--G---GI-DLQLLGIGENGHIG--FnePGSSLdsrtrvvtLDESTRQANArfFDGDEDVPTQAI 171

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 71896147 179 TLTLPVLNAARTVVFVATGEGKAAVLKRILEGNEENPLPAARVRPHTGQLLWfLDEAAAKEL 240
Cdd:cd01399 172 TMGIGTIMKAKEILLLATGEGKAEAVKKALEGPVTEECPASILQLHPNVTVI-LDEAAASEL 232
nagB PRK00443
glucosamine-6-phosphate deaminase; Provisional
 4-242 3.58e-13

glucosamine-6-phosphate deaminase; Provisional


Pssm-ID: 179028 [Multi-domain]  Cd Length: 261  Bit Score: 67.16  E-value: 3.58e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71896147    4 RISVFPSPQELGSALAQLVVQRA----AGSDGRFSLGLSGGS--------LVGLLARElplaattgaatgAGPW--LVAF 69
Cdd:PRK00443   2 RLIILKTAEEVGKWAARHIANRInaflPTKERPFVLGLATGSspletykaLIELHKAG------------KVDFsrVTTF 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71896147   70 -CDERL-VPPEHPEStFGAY-SAQLLPWLPAPAPTV-LAVAPGLSPNAAAADYAERLREAfqgdaVPVfDLLLLGVGPDG 145
Cdd:PRK00443  70 nLDEYVgLPADHPES-YRYFmRENFFDHVDIPPENInLLNGNAPDPEAECRRYEEKIKSA-----GGI-DLQILGIGENG 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71896147  146 H------TCSLfpNHP----LLQEKEKIVAA------ITDSPKpppQRITLTLPVLNAARTVVFVATGEGKAAVLKRILE 209
Cdd:PRK00443 143 HiafnepGSSF--ASRtrikTLTEDTRIANSrffdgdIEQVPK---YALTVGVGTILDAKEIMLLAPGHNKAEAVKAAVE 217

                        250       260       270
                 ....*....|....*....|....*....|...
gi 71896147  210 GNEENPLPAARVRPHTGQLLwFLDEAAAKELTV 242
Cdd:PRK00443 218 GPVNHMWPASILQLHPKATL-VLDEAAASELKV 249
PRK12358 PRK12358
glucosamine-6-phosphate deaminase;
135-240 1.75e-12

glucosamine-6-phosphate deaminase;


Pssm-ID: 183470  Cd Length: 239  Bit Score: 64.77  E-value: 1.75e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71896147  135 DLLLLGVGPDGHTCSLFPNH----------PLLQEKEKIVAAITDSPKP---PPQRITLTLPVLNAARTVVFVATGEGKA 201
Cdd:PRK12358 120 DLVVLGLGADGHFCGNLPGTthfhdetvevPIQGEMVDIVAHGELGGDFslvPDSYVTMGPKSIMAAKNLLLIVNGKGKA 199

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 71896147  202 AVLKRILEGNEENPLPAARVRPHTgQLLWFLDEAAAKEL 240
Cdd:PRK12358 200 QILKKVLQGPVTEDVPASILQLHP-NLTVILDEAAAAEL 237
PTZ00285 PTZ00285
glucosamine-6-phosphate isomerase; Provisional
 4-242 2.59e-10

glucosamine-6-phosphate isomerase; Provisional


Pssm-ID: 140308  Cd Length: 253  Bit Score: 59.00  E-value: 2.59e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71896147    4 RISVFPSPQELGSALAQLVVQRAA----GSDGRFSLGLSGGSLVGLLARELplaattgaatgagpwLVAFCDERL----- 74
Cdd:PTZ00285   2 RIVISEDADAVADYTSNYIIKRINdfkpTSDRPFVLGLPTGSTPLPTYQEL---------------IRAYREGRVsfsnv 66

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71896147   75 ----------VPPEHPESTFGAYSAQLLPWLPAPaPTVLAVAPGLSPNAAA--ADYAERLReafqgdAVPVFDLLLLGVG 142
Cdd:PTZ00285  67 vtfnmdeyvgLPRDHPQSYHYFMKENFFDHVDIK-EENRHILNGTAPDLEEecRRYEEKIR------AVGGIDLFLAGIG 139

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71896147  143 PDGHTCSLFPNHPLLQE-------KEKIVAAI----TDSPKPPPQRITLTLPVLNAARTVVFVATGEGKAAVLKRILEGN 211
Cdd:PTZ00285 140 TDGHIAFNEPGSSLDSRtrvkslnQETIDANArffgNDISKVPTMALTVGIRTIMEAREVLLLATGASKAIAVARCVEGG 219

                        250       260       270
                 ....*....|....*....|....*....|.
gi 71896147  212 EENPLPAARVRPHTGQLLwFLDEAAAKELTV 242
Cdd:PTZ00285 220 VTHMCPASALQMHPAAVL-CLDEDATLELKV 249
PRK02122 PRK02122
glucosamine-6-phosphate deaminase-like protein; Validated
 112-241 2.20e-08

glucosamine-6-phosphate deaminase-like protein; Validated


Pssm-ID: 235005 [Multi-domain]  Cd Length: 652  Bit Score: 54.26  E-value: 2.20e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71896147  112 NAAAADYAERLrEAFQGdavpvFDLLLLGVGPDGHtcsLFPNHP-----------LLQEKEKIVAAIT--DSPKPPPQRI 178
Cdd:PRK02122 143 DEYCRDYEEKI-EAAGG-----IDFQLLGIGRTGH---IGFNEPgsgrnsrtrlvTLDHITRRDAASDffGEENVPRKAI 213

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 71896147  179 TLTLPVLNAARTVVFVATGEGKAAVLKRILEGNEENPLPAARVRPHTGQLLwFLDEAAAKELT 241
Cdd:PRK02122 214 TMGVGTILKARRIVLLAWGEHKAPIIKRAVEGEISDEVPASYLQEHPNATF-VLDLAAASELT 275
PRK09762 PRK09762
galactosamine-6-phosphate isomerase; Provisional
 112-219 3.36e-05

galactosamine-6-phosphate isomerase; Provisional


Pssm-ID: 182064  Cd Length: 232  Bit Score: 43.66  E-value: 3.36e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71896147  112 NAAAADYAERLREAFQGDAVPVFDLLLLGVGPDGH------TCSLFPNHPL--LQEKEKIVAAITDSPKPPPQRITLTLP 183
Cdd:PRK09762 103 RSEEINETECERVTNLIARKGGLDLCVLGLGKNGHlglnepGESLQPACHIsqLDARTQQHEMLKTAGRPVTRGITLGLK 182

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 71896147  184 VLNAARTVVFVATGEGKAAVLKRILEGNEENPLPAA 219
Cdd:PRK09762 183 DILNAREVLLLVTGEGKQDATERFLTAKVSTAIPAS 218
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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