|
Name |
Accession |
Description |
Interval |
E-value |
| MrcA |
COG5009 |
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis]; |
21-758 |
0e+00 |
|
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 444033 [Multi-domain] Cd Length: 785 Bit Score: 961.93 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 21 RIGRFLFQSIIFCIGLGLCGLLLgtlAVALTWPNLPDLKAMTDYRPRVPLRVYTADKILLAEYGEERRNVLRFNEIPDVM 100
Cdd:COG5009 2 RLLKILLILLLLLLLLGALAVAG---LYLYLSPDLPDVETLKDYQPPTPSRVYSADGKLIAEFGEERRIPVPIEEIPPLL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 101 KHALLAAEDDNFYNHGGVDWSGVGRAVIANVVSGAKAQGASTITMQVARNFYLSSEKSFIRKFYELMLTYKIEQNLSKDQ 180
Cdd:COG5009 79 INAFLAAEDKRFYEHPGVDPIGIARAAVVNLRTGRRVQGGSTITQQVAKNFLLSPERTLTRKIKEAILALRIEQELSKDE 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 181 ILELYLNQIYLGHRSYGFAAASRTYYGKPLSEVSIAEAALLAGIPKAPSRFNPRANLKRAVARQHYVLDRMEKLGYITPE 260
Cdd:COG5009 159 ILELYLNKIYLGHRAYGVAAAAQTYFGKSLDELTLAEAAMLAGLPKAPSRYNPIRNPERALERRNYVLGRMLELGYITQA 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 261 QHQEALAQKIVLRDNTQETPEttfarHGQYVAELARQLMYNVY-KDNVYGRGLSVYTTIRSQDQEVAYHAVRDGIMSYTR 339
Cdd:COG5009 239 EYEAAKAEPLTARYHGASAEV-----DAPYFAEMVRRELVERYgEDALYTGGLKVYTTLDPRLQEAAEKALRDGLLAYDR 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 340 RKPYPGPAAQVDLPAGiennterfdlALEEIRNKYRDSDDLVTAVVLSASASKVVAARTPEQIYELSGKSLGYVKRALTN 419
Cdd:COG5009 314 RHGYRGPEAHLDLAEE----------DWDEALAEVPDVGDLRPAVVLEVDDKSARVGLRDGETGTLPLEGLKWARPYIND 383
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 420 S--GPT----SRRIQRGSVIYLQKV-DNTWTIINMPTVEGAFISLNPQNGAIESMIGGFDFNRGDFNRVTQAWRQPGSTF 492
Cdd:COG5009 384 NrrGPApksaSDVLKPGDVIRVRPVaDGGWRLRQIPEVQGALVALDPHTGAVLALVGGFDFEQSKFNRATQAKRQPGSSF 463
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 493 KPFVYAAGLERGVTPGTNISDQPFHLSAAQtRSKPWSPKNYGNSYSYSQTMRQGLYKSKNMVSIRILQTVGPEFASEFIS 572
Cdd:COG5009 464 KPFVYAAALDNGYTPATIINDAPIVFDDGG-GGGVWRPKNYSGKFYGPTTLREALEKSRNLVTVRLLQDVGIDYVIDYAE 542
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 573 RFGFDpARQPPksaYLTMALGAGSVTPLQMASAYSVFANGGYRVNPYIIDSVVDiSTGRVIMKAQPAMAGDE-------- 644
Cdd:COG5009 543 RFGIY-SKLPP---NLSLALGSGEVTPLEMARAYAVFANGGYRVEPYLIDRIED-RNGKVIYRADPARACEDcdaaewdg 617
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 645 --------ANRVLDPRTAYVMNDLLRGVAKSGTAARTQAtLKRgDIGGKTGTTNQSYDAWFAGFTPKLVGISWLGFDQPK 716
Cdd:COG5009 618 aeprlpdpAEQVIDPRTAYQMTSMLRGVVQRGTGRRARA-LGR-DIAGKTGTTNDSKDAWFVGFTPDLVAGVWVGFDDPR 695
|
730 740 750 760
....*....|....*....|....*....|....*....|..
gi 754694470 717 SLGDKETGGGAAMPIWLSYMQTALKKVPVTPPgPIPEGLAKV 758
Cdd:COG5009 696 SLGRGETGGRAALPIWIDFMKAALKDKPEKPF-PVPEGIVTV 736
|
|
| PBP_1a_fam |
TIGR02074 |
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan ... |
87-742 |
0e+00 |
|
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273955 [Multi-domain] Cd Length: 531 Bit Score: 579.99 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 87 RRNVLRFNEIPDVMKHALLAAEDDNFYNHGGVDWSGVGRAVIANVVSGAKAQGASTITMQVARNFYLSSEKSFIRKFYEL 166
Cdd:TIGR02074 1 RREYVPIDDIPENLINAFLAIEDRRFYDHFGIDLKGIGRAAVANITSGRVLEGGSTITQQLAKNLYLTNERTITRKIQEA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 167 MLTYKIEQNLSKDQILELYLNQIYLGHRSYGFAAASRTYYGKPLSEVSIAEAALLAGIPKAPSRFNPRANLKRAVARQHY 246
Cdd:TIGR02074 81 LLALKLEQKLSKDEILELYLNRIYFGNGAYGIEAAAQFYFGKSVNDLTLAEAAMLAGLPKAPSAYNPFKNPERAKDRRNL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 247 VLDRMEKLGYITPEQHQEALAQKIVLRDNTQETPETTFarhgQYVAELARQLMYNVYKDNVYGRGLSVYTTIRSQDQEVA 326
Cdd:TIGR02074 161 VLSNMVENGYITAEEAEEAINEPIQLYLQTKKSEQYKA----PYFVDYVIQELEEEYGEELYTGGLKIYTTLDLDAQKAA 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 327 YHAVRDGImsytrrkpypgpaaqvdlpagiennterfdlaleeiRNKYRDSDDLVtavvlsasaskvvaartpeqiyels 406
Cdd:TIGR02074 237 EKVLNTGL------------------------------------RVAGRRDGDDL------------------------- 255
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 407 gkslgyvkraltnsgptsrriqrgsviylqkvdntwtiinmptvEGAFISLNPQNGAIESMIGGFDFNRGDFNRVTQAWR 486
Cdd:TIGR02074 256 --------------------------------------------QAALVAIDPDTGAVRALVGGRDYGKSQFNRATQAKR 291
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 487 QPGSTFKPFVYAAGLERGVTPGTNISDQPFHLSaaqtRSKPWSPKNYGNSYSYSQTMRQGLYKSKNMVSIRILQTVGPEF 566
Cdd:TIGR02074 292 QPGSTFKPFVYAAALEKGLTPATIVNDEPITYN----GNGPWSPKNYGGGYRGNVTLRQALAQSRNIPAVRLLQEVGLDK 367
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 567 ASEFISRFGFDparqPPKSAYLTMALGAGSVTPLQMASAYSVFANGGYRVNPYIIDSVVDiSTGRVIMKAQPamagdEAN 646
Cdd:TIGR02074 368 VVALAKRFGIT----SPLDPVLSLALGTVEVSPLEMASAYAVFANGGKYVEPHGIRKIVD-RDGKVIYENKP-----KTT 437
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 647 RVLDPRTAYVMNDLLRGVAKSGTAARtqATLKRGDIGGKTGTTNQSYDAWFAGFTPKLVGISWLGFDQPKSLGDKETGGG 726
Cdd:TIGR02074 438 QVISPATAYIMTDMLKGVVESGTGRS--ARLPGRPVAGKTGTTQNWRDAWFVGYTPYYVTAVWVGYDDKKTLGKSGTGGG 515
|
650
....*....|....*.
gi 754694470 727 AAMPIWLSYMQTALKK 742
Cdd:TIGR02074 516 LAAPIWRDFMAEALKN 531
|
|
| mrcA |
PRK11636 |
penicillin-binding protein 1a; Provisional |
53-758 |
0e+00 |
|
penicillin-binding protein 1a; Provisional
Pssm-ID: 183248 [Multi-domain] Cd Length: 850 Bit Score: 572.85 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 53 PNLPDLKAMTDYRPRVPLRVYTADKILLAEYGEERRNVLRFNEIPDVMKHALLAAEDDNFYNHGGVDWSGVGRAVIANVV 132
Cdd:PRK11636 31 PQLPDVATLKDVRLQTPMQVYSADGELIAQYGEKRRIPLTLDQIPPEMVKAFIATEDSRFYEHHGVDPVGIFRAASVALF 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 133 SGAKAQGASTITMQVARNFYLSSEKSFIRKFYELMLTYKIEQNLSKDQILELYLNQIYLGHRSYGFAAASRTYYGKPLSE 212
Cdd:PRK11636 111 SGHASQGASTITQQLARNFFLSPERTLMRKIKEAFLAIRIEQLLTKDEILELYLNKIYLGYRAYGVGAAAQVYFGKTVDQ 190
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 213 VSIAEAALLAGIPKAPSRFNPRANLKRAVARQHYVLDRMEKLGYITPEQHQEALAQKIVLRdntQETPETTFArhGQYVA 292
Cdd:PRK11636 191 LTLSEMAVIAGLPKAPSTFNPLYSMDRAVARRNVVLSRMLDEGYITQAQYDQARSEPIVAN---YHAPEIAFS--APYLS 265
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 293 ELARQLMYNVYKDNVYGRGLSVYTTIRSQDQEVAYHAVRDGIMSYTRRKPYPGPAAQVDLPAGIENNTERFDLALEEIRN 372
Cdd:PRK11636 266 EMVRQEMYNRYGENAYEDGYRVYTTITRKVQQAAQQAVRNNVLDYDMRHGYRGPANVLWKVGESAWDNKKITDTLKALPT 345
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 373 kyrdSDDLVTAVVLSASASKVVAARTPEQIYELSGKSLGYVK--RALTNSGPTSRR----IQRGSVIYLQKVDNTWTIIN 446
Cdd:PRK11636 346 ----YGPLLPAVVTSANPQEATAMLADGSSVALPMEGVRWARpyRSDTQQGPTPRKvtdvVQTGQQIWVRQVDDAWWLAQ 421
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 447 MPTVEGAFISLNPQNGAIESMIGGFDFNRGDFNRVTQAWRQPGSTFKPFVYAAGLERGVTPGTNISDQPFHLSAAQTRSK 526
Cdd:PRK11636 422 VPDVNSALVSINPQNGAVMALVGGFDFNQSKFNRATQALRQVGSNIKPFLYTAAMDKGLTLASMLNDVPISRWDAGAGSD 501
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 527 pWSPKNYGNSYSYSQTMRQGLYKSKNMVSIRILQTVGPEFASEFISRFGFdPARQPPKSAylTMALGAGSVTPLQMASAY 606
Cdd:PRK11636 502 -WRPKNSPPQYAGPIRLRQGLGQSKNVVMVRAMRAMGVDYAAEYLQRFGF-PAQNIVHTE--SLALGSASFTPMQVARGY 577
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 607 SVFANGGYRVNPYIIDSVVDiSTGRVIMKAQPAMAGDEANRVL----DPRTAYVMNDLLRGVAKS--------------- 667
Cdd:PRK11636 578 AVMANGGFLVDPYFISKIEN-DQGGVIFEAKPKVACPECDIPViygdTQKSNVLENDDVENVATSqeqqnssvpmpqleq 656
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 668 ------------------------------------------GTAARTQATLKRGDIGGKTGTTNQSYDAWFAGFTPKLV 705
Cdd:PRK11636 657 anqalvaqngaqeyaphvintplafliksalntnifgepgwmGTGWRAGRDLKRRDIGGKTGTTNSSKDAWFSGYGPGVV 736
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 754694470 706 GISWLGFD-QPKSLG---------DKETG--GGA--AMPIWLSYMQTALKKVPVTPPGPiPEGLAKV 758
Cdd:PRK11636 737 TSVWIGFDdHRRDLGrttasgaikDQISGyeGGAksAQPAWDDYMKAALEGVPEQPLTP-PPGIVTV 802
|
|
| Transgly |
pfam00912 |
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of ... |
76-252 |
1.44e-83 |
|
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.
Pssm-ID: 459993 [Multi-domain] Cd Length: 177 Bit Score: 264.00 E-value: 1.44e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 76 DKILLAEYGEERRNVLRFNEIPDVMKHALLAAEDDNFYNHGGVDWSGVGRAVIANVVSGAKAQGASTITMQVARNFYLSS 155
Cdd:pfam00912 1 DGTLLAELGEENREYVPLDDIPPALKNAVLAIEDRRFYEHGGVDPKGIARALLSNLRSGRIVQGGSTITQQLAKNLFLTP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 156 EKSFIRKFYELMLTYKIEQNLSKDQILELYLNQIYLGHRSYGFAAASRTYYGKPLSEVSIAEAALLAGIPKAPSRFNPRA 235
Cdd:pfam00912 81 ERTLTRKLKEAVLALKLERRYSKDEILEAYLNTVYFGRGAYGIEAAARAYFGKDASDLTLAEAALLAGLPQAPSRYNPLR 160
|
170
....*....|....*..
gi 754694470 236 NLKRAVARQHYVLDRME 252
Cdd:pfam00912 161 NPERAKRRRNLVLDRMV 177
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| MrcA |
COG5009 |
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis]; |
21-758 |
0e+00 |
|
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 444033 [Multi-domain] Cd Length: 785 Bit Score: 961.93 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 21 RIGRFLFQSIIFCIGLGLCGLLLgtlAVALTWPNLPDLKAMTDYRPRVPLRVYTADKILLAEYGEERRNVLRFNEIPDVM 100
Cdd:COG5009 2 RLLKILLILLLLLLLLGALAVAG---LYLYLSPDLPDVETLKDYQPPTPSRVYSADGKLIAEFGEERRIPVPIEEIPPLL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 101 KHALLAAEDDNFYNHGGVDWSGVGRAVIANVVSGAKAQGASTITMQVARNFYLSSEKSFIRKFYELMLTYKIEQNLSKDQ 180
Cdd:COG5009 79 INAFLAAEDKRFYEHPGVDPIGIARAAVVNLRTGRRVQGGSTITQQVAKNFLLSPERTLTRKIKEAILALRIEQELSKDE 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 181 ILELYLNQIYLGHRSYGFAAASRTYYGKPLSEVSIAEAALLAGIPKAPSRFNPRANLKRAVARQHYVLDRMEKLGYITPE 260
Cdd:COG5009 159 ILELYLNKIYLGHRAYGVAAAAQTYFGKSLDELTLAEAAMLAGLPKAPSRYNPIRNPERALERRNYVLGRMLELGYITQA 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 261 QHQEALAQKIVLRDNTQETPEttfarHGQYVAELARQLMYNVY-KDNVYGRGLSVYTTIRSQDQEVAYHAVRDGIMSYTR 339
Cdd:COG5009 239 EYEAAKAEPLTARYHGASAEV-----DAPYFAEMVRRELVERYgEDALYTGGLKVYTTLDPRLQEAAEKALRDGLLAYDR 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 340 RKPYPGPAAQVDLPAGiennterfdlALEEIRNKYRDSDDLVTAVVLSASASKVVAARTPEQIYELSGKSLGYVKRALTN 419
Cdd:COG5009 314 RHGYRGPEAHLDLAEE----------DWDEALAEVPDVGDLRPAVVLEVDDKSARVGLRDGETGTLPLEGLKWARPYIND 383
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 420 S--GPT----SRRIQRGSVIYLQKV-DNTWTIINMPTVEGAFISLNPQNGAIESMIGGFDFNRGDFNRVTQAWRQPGSTF 492
Cdd:COG5009 384 NrrGPApksaSDVLKPGDVIRVRPVaDGGWRLRQIPEVQGALVALDPHTGAVLALVGGFDFEQSKFNRATQAKRQPGSSF 463
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 493 KPFVYAAGLERGVTPGTNISDQPFHLSAAQtRSKPWSPKNYGNSYSYSQTMRQGLYKSKNMVSIRILQTVGPEFASEFIS 572
Cdd:COG5009 464 KPFVYAAALDNGYTPATIINDAPIVFDDGG-GGGVWRPKNYSGKFYGPTTLREALEKSRNLVTVRLLQDVGIDYVIDYAE 542
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 573 RFGFDpARQPPksaYLTMALGAGSVTPLQMASAYSVFANGGYRVNPYIIDSVVDiSTGRVIMKAQPAMAGDE-------- 644
Cdd:COG5009 543 RFGIY-SKLPP---NLSLALGSGEVTPLEMARAYAVFANGGYRVEPYLIDRIED-RNGKVIYRADPARACEDcdaaewdg 617
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 645 --------ANRVLDPRTAYVMNDLLRGVAKSGTAARTQAtLKRgDIGGKTGTTNQSYDAWFAGFTPKLVGISWLGFDQPK 716
Cdd:COG5009 618 aeprlpdpAEQVIDPRTAYQMTSMLRGVVQRGTGRRARA-LGR-DIAGKTGTTNDSKDAWFVGFTPDLVAGVWVGFDDPR 695
|
730 740 750 760
....*....|....*....|....*....|....*....|..
gi 754694470 717 SLGDKETGGGAAMPIWLSYMQTALKKVPVTPPgPIPEGLAKV 758
Cdd:COG5009 696 SLGRGETGGRAALPIWIDFMKAALKDKPEKPF-PVPEGIVTV 736
|
|
| MrcB |
COG0744 |
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall ... |
15-758 |
0e+00 |
|
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440507 [Multi-domain] Cd Length: 630 Bit Score: 646.59 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 15 RSSAGSRIGRFLFQSIIFCIGLGLCGLLLGtlAVALTWPNLPDLKAMTDYRPRVPLRVYTADKILLAEYGEERRNVLRFN 94
Cdd:COG0744 3 KPRRGKRLLRRLLGLLLLLLAVLVLAALAG--LVALYVADLPDPEELEDLALPQTSTIYDRDGTLIATLGDENREWVPLD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 95 EIPDVMKHALLAAEDDNFYNHGGVDWSGVGRAVIANVVSGAKAQGASTITMQVARNFYLSSEKSFIRKFYELMLTYKIEQ 174
Cdd:COG0744 81 QIPPHLKDAVVAIEDRRFYEHGGVDPKGIARALVANLTAGGVVQGGSTITQQLVKNLFLSNERTLSRKLKEALLALKLER 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 175 NLSKDQILELYLNQIYLGHRSYGFAAASRTYYGKPLSEVSIAEAALLAGIPKAPSRFNPRANLKRAVARQHYVLDRMEKL 254
Cdd:COG0744 161 KYSKDEILELYLNTVYFGRGAYGIEAAAQYYFGKSASDLTLAEAALLAGLVKAPSYYDPYRNPEAAKERRNLVLDRMVEQ 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 255 GYITPEQHQEALAQKIVLRDNTQETPETtfaRHGQYVAELARQLMYNVYKDNVYGRGLSVYTTIRSQDQEVAYHAVRDGi 334
Cdd:COG0744 241 GYITQAEADAAKAEPLTLVPPPNGAAAG---KYPYFVDYVRRELEELLGEDDLYRGGLKIYTTLDPKLQKAAEKAVKNV- 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 335 msytrrkpypgpaaqvdLPAGiennterfdlaleeirnkyrdsddlvtavvlsasaskvvaartpeqiyelsgkslgyvk 414
Cdd:COG0744 317 -----------------LPEG----------------------------------------------------------- 320
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 415 raltnsgptsrriqrgsviylqkvdntwtiiNMPTVEGAFISLNPQNGAIESMIGGFDFNRGDFNRVTQAWRQPGSTFKP 494
Cdd:COG0744 321 -------------------------------KPGGLQAALVVVDPKTGEVLAMVGGRDYGKSQFNRATQAKRQPGSTFKP 369
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 495 FVYAAGLERGVTPGTNISDQPFHLsaaqtRSKPWSPKNYGNSYSYSQTMRQGLYKSKNMVSIRILQTVGPEFASEFISRF 574
Cdd:COG0744 370 FVYAAALEQGYTPATTVDDEPVTF-----PGGGWSPKNYDGRYRGPVTLREALANSLNTPAVRLAQEVGLDKVVDTARRL 444
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 575 GFDparqPPKSAYLTMALGAGSVTPLQMASAYSVFANGGYRVNPYIIDSVVDiSTGRVIMKAQPamagdEANRVLDPRTA 654
Cdd:COG0744 445 GIT----SPLDPNPSLALGTSEVSPLEMASAYATFANGGVYVEPHAITKVTD-ADGKVLYEAKP-----KCEQVISPEVA 514
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 655 YVMNDLLRGVAKSGTAARtqATLKRGDIGGKTGTTNQSYDAWFAGFTPKLVGISWLGFDQPKSLGdKETGGGAAMPIWLS 734
Cdd:COG0744 515 YLMTDMLQDVVTSGTGRA--ARLPGRPVAGKTGTTNDNRDAWFVGYTPQLVTAVWVGNDDNSPMG-YVTGGSLPAPIWRD 591
|
730 740
....*....|....*....|....
gi 754694470 735 YMQTALKKVPVTPPgPIPEGLAKV 758
Cdd:COG0744 592 FMEAALEGLPVEDF-PKPSGVVRI 614
|
|
| PBP_1a_fam |
TIGR02074 |
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan ... |
87-742 |
0e+00 |
|
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273955 [Multi-domain] Cd Length: 531 Bit Score: 579.99 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 87 RRNVLRFNEIPDVMKHALLAAEDDNFYNHGGVDWSGVGRAVIANVVSGAKAQGASTITMQVARNFYLSSEKSFIRKFYEL 166
Cdd:TIGR02074 1 RREYVPIDDIPENLINAFLAIEDRRFYDHFGIDLKGIGRAAVANITSGRVLEGGSTITQQLAKNLYLTNERTITRKIQEA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 167 MLTYKIEQNLSKDQILELYLNQIYLGHRSYGFAAASRTYYGKPLSEVSIAEAALLAGIPKAPSRFNPRANLKRAVARQHY 246
Cdd:TIGR02074 81 LLALKLEQKLSKDEILELYLNRIYFGNGAYGIEAAAQFYFGKSVNDLTLAEAAMLAGLPKAPSAYNPFKNPERAKDRRNL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 247 VLDRMEKLGYITPEQHQEALAQKIVLRDNTQETPETTFarhgQYVAELARQLMYNVYKDNVYGRGLSVYTTIRSQDQEVA 326
Cdd:TIGR02074 161 VLSNMVENGYITAEEAEEAINEPIQLYLQTKKSEQYKA----PYFVDYVIQELEEEYGEELYTGGLKIYTTLDLDAQKAA 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 327 YHAVRDGImsytrrkpypgpaaqvdlpagiennterfdlaleeiRNKYRDSDDLVtavvlsasaskvvaartpeqiyels 406
Cdd:TIGR02074 237 EKVLNTGL------------------------------------RVAGRRDGDDL------------------------- 255
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 407 gkslgyvkraltnsgptsrriqrgsviylqkvdntwtiinmptvEGAFISLNPQNGAIESMIGGFDFNRGDFNRVTQAWR 486
Cdd:TIGR02074 256 --------------------------------------------QAALVAIDPDTGAVRALVGGRDYGKSQFNRATQAKR 291
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 487 QPGSTFKPFVYAAGLERGVTPGTNISDQPFHLSaaqtRSKPWSPKNYGNSYSYSQTMRQGLYKSKNMVSIRILQTVGPEF 566
Cdd:TIGR02074 292 QPGSTFKPFVYAAALEKGLTPATIVNDEPITYN----GNGPWSPKNYGGGYRGNVTLRQALAQSRNIPAVRLLQEVGLDK 367
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 567 ASEFISRFGFDparqPPKSAYLTMALGAGSVTPLQMASAYSVFANGGYRVNPYIIDSVVDiSTGRVIMKAQPamagdEAN 646
Cdd:TIGR02074 368 VVALAKRFGIT----SPLDPVLSLALGTVEVSPLEMASAYAVFANGGKYVEPHGIRKIVD-RDGKVIYENKP-----KTT 437
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 647 RVLDPRTAYVMNDLLRGVAKSGTAARtqATLKRGDIGGKTGTTNQSYDAWFAGFTPKLVGISWLGFDQPKSLGDKETGGG 726
Cdd:TIGR02074 438 QVISPATAYIMTDMLKGVVESGTGRS--ARLPGRPVAGKTGTTQNWRDAWFVGYTPYYVTAVWVGYDDKKTLGKSGTGGG 515
|
650
....*....|....*.
gi 754694470 727 AAMPIWLSYMQTALKK 742
Cdd:TIGR02074 516 LAAPIWRDFMAEALKN 531
|
|
| mrcA |
PRK11636 |
penicillin-binding protein 1a; Provisional |
53-758 |
0e+00 |
|
penicillin-binding protein 1a; Provisional
Pssm-ID: 183248 [Multi-domain] Cd Length: 850 Bit Score: 572.85 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 53 PNLPDLKAMTDYRPRVPLRVYTADKILLAEYGEERRNVLRFNEIPDVMKHALLAAEDDNFYNHGGVDWSGVGRAVIANVV 132
Cdd:PRK11636 31 PQLPDVATLKDVRLQTPMQVYSADGELIAQYGEKRRIPLTLDQIPPEMVKAFIATEDSRFYEHHGVDPVGIFRAASVALF 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 133 SGAKAQGASTITMQVARNFYLSSEKSFIRKFYELMLTYKIEQNLSKDQILELYLNQIYLGHRSYGFAAASRTYYGKPLSE 212
Cdd:PRK11636 111 SGHASQGASTITQQLARNFFLSPERTLMRKIKEAFLAIRIEQLLTKDEILELYLNKIYLGYRAYGVGAAAQVYFGKTVDQ 190
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 213 VSIAEAALLAGIPKAPSRFNPRANLKRAVARQHYVLDRMEKLGYITPEQHQEALAQKIVLRdntQETPETTFArhGQYVA 292
Cdd:PRK11636 191 LTLSEMAVIAGLPKAPSTFNPLYSMDRAVARRNVVLSRMLDEGYITQAQYDQARSEPIVAN---YHAPEIAFS--APYLS 265
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 293 ELARQLMYNVYKDNVYGRGLSVYTTIRSQDQEVAYHAVRDGIMSYTRRKPYPGPAAQVDLPAGIENNTERFDLALEEIRN 372
Cdd:PRK11636 266 EMVRQEMYNRYGENAYEDGYRVYTTITRKVQQAAQQAVRNNVLDYDMRHGYRGPANVLWKVGESAWDNKKITDTLKALPT 345
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 373 kyrdSDDLVTAVVLSASASKVVAARTPEQIYELSGKSLGYVK--RALTNSGPTSRR----IQRGSVIYLQKVDNTWTIIN 446
Cdd:PRK11636 346 ----YGPLLPAVVTSANPQEATAMLADGSSVALPMEGVRWARpyRSDTQQGPTPRKvtdvVQTGQQIWVRQVDDAWWLAQ 421
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 447 MPTVEGAFISLNPQNGAIESMIGGFDFNRGDFNRVTQAWRQPGSTFKPFVYAAGLERGVTPGTNISDQPFHLSAAQTRSK 526
Cdd:PRK11636 422 VPDVNSALVSINPQNGAVMALVGGFDFNQSKFNRATQALRQVGSNIKPFLYTAAMDKGLTLASMLNDVPISRWDAGAGSD 501
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 527 pWSPKNYGNSYSYSQTMRQGLYKSKNMVSIRILQTVGPEFASEFISRFGFdPARQPPKSAylTMALGAGSVTPLQMASAY 606
Cdd:PRK11636 502 -WRPKNSPPQYAGPIRLRQGLGQSKNVVMVRAMRAMGVDYAAEYLQRFGF-PAQNIVHTE--SLALGSASFTPMQVARGY 577
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 607 SVFANGGYRVNPYIIDSVVDiSTGRVIMKAQPAMAGDEANRVL----DPRTAYVMNDLLRGVAKS--------------- 667
Cdd:PRK11636 578 AVMANGGFLVDPYFISKIEN-DQGGVIFEAKPKVACPECDIPViygdTQKSNVLENDDVENVATSqeqqnssvpmpqleq 656
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 668 ------------------------------------------GTAARTQATLKRGDIGGKTGTTNQSYDAWFAGFTPKLV 705
Cdd:PRK11636 657 anqalvaqngaqeyaphvintplafliksalntnifgepgwmGTGWRAGRDLKRRDIGGKTGTTNSSKDAWFSGYGPGVV 736
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 754694470 706 GISWLGFD-QPKSLG---------DKETG--GGA--AMPIWLSYMQTALKKVPVTPPGPiPEGLAKV 758
Cdd:PRK11636 737 TSVWIGFDdHRRDLGrttasgaikDQISGyeGGAksAQPAWDDYMKAALEGVPEQPLTP-PPGIVTV 802
|
|
| PBP_1b |
TIGR02071 |
penicillin-binding protein 1B; Bacterial that synthesize a cell wall of peptidoglycan (murein) ... |
84-763 |
3.06e-106 |
|
penicillin-binding protein 1B; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of a particular bifunctional transglycosylase/transpeptidase in E. coli and other Proteobacteria, designated penicillin-binding protein 1B. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273952 [Multi-domain] Cd Length: 730 Bit Score: 342.86 E-value: 3.06e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 84 GEERRNVlRFNEIPDVMKHALLAAEDDNFYNHGGVDWSGVGRAVIANVVSGAKAQGASTITMQVARNFYLSSEKSFIRKF 163
Cdd:TIGR02071 144 GEQRLFV-PRDQFPELLVDTLLATEDRDFYEHDGISLYSIGRAVWVNLTAGRTVQGGSTLTQQLVKNLFLSNERSLWRKA 222
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 164 YELMLTYKIEQNLSKDQILELYLNQIYLGHRS----YGFAAASRTYYGKPLSEVSIAEAALLAGIPKAPSRFNPRANLKR 239
Cdd:TIGR02071 223 NEAYMALILDARYSKDRILELYLNEVYLGQSGddaiHGFPLASQYYFGRPLGELSLDQVALLVGMVKGPSYYNPWRNPDR 302
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 240 AVARQHYVLDRMEKLGYITPEQHQEALAQKIvlrdNTQETPETTfARHGQYVAELARQLMYNVYKDNVYGRGLSVYTTIR 319
Cdd:TIGR02071 303 ALERRNLVLRLLQEQKIIDDEEYDMLSARPL----GVQKKGGII-SRQPAFLQLVRRELRQKLGDKVKDLSGLRIFTTLD 377
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 320 SQDQEVAYHAVRDGIMSYTRRKpypgpaaqvdlpagiennterfdlaleeirnkyrdsddlvtavvlsasaskvvaartp 399
Cdd:TIGR02071 378 PVSQSAAEQAVQETIPALKKKK---------------------------------------------------------- 399
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 400 eqiyelsgkslgyvkraltnsgptsrriqrgsviylqkvdntwtiiNMPTVEGAFISLNPQNGAIESMIGGFDFNRGDFN 479
Cdd:TIGR02071 400 ----------------------------------------------KLPDLEAAMVVTDRFTGEVRAMVGGSDPQFAGFN 433
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 480 RVTQAWRQPGSTFKPFVYAAGLER--GVTPGTNISDQPFHLSAAQtrSKPWSPKNYGNSYSYSQTMRQGLYKSKNMVSIR 557
Cdd:TIGR02071 434 RALQARRQIGSLVKPAVYLTALSQpdKYRLNTWIEDQPLSIKLSN--GQVWSPQNYDRRYSGTVMLYDALAHSLNIPTVN 511
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 558 ILQTVGPEFASEFISRFGFDPARQPPksaYLTMALGAGSVTPLQMASAYSVFANGGYRVNPYIIDSVVDiSTGRVIMKAQ 637
Cdd:TIGR02071 512 LGMKVGLPKVSQTWNKLGINKDEIPP---VPSMLLGAINLTPYEVAQLYQTIASGGNRAPLSAVRSVLD-EDGKVLYQSD 587
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 638 PamagdEANRVLDPRTAYVMNDLLRGVAKSGTAARTQATLKRGDIGGKTGTTNQSYDAWFAGFTPKLVGISWLGFD--QP 715
Cdd:TIGR02071 588 P-----QAEQAVPSQAAYLTLYAMQQVVQRGTARSLGADFPSLSLAGKTGTTNDNRDSWFAGIDGKEVTIIWLGRDdnGP 662
|
650 660 670 680
....*....|....*....|....*....|....*....|....*...
gi 754694470 716 KSLgdkeTGGGAAMPIWLSYMQtalKKVPVTPPGPIPEGLAKVGDNFY 763
Cdd:TIGR02071 663 TKL----TGASGALQVYARYLS---YQTPEPLLLVPPEGIDWFGVDPQ 703
|
|
| PbpC |
COG4953 |
Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope ... |
47-758 |
6.35e-94 |
|
Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 443980 [Multi-domain] Cd Length: 773 Bit Score: 311.00 E-value: 6.35e-94
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 47 AVALTWPnLPDLKAmTDYRPRV------PLRVYTADKillaeygEERRNVLRFNEIPDVMKHALLAAEDDNFYNHGGVDW 120
Cdd:COG4953 27 ALDRLFP-LPLLFA-VPYSTVVldrdgtLLRAFLAAD-------GQWRLPVPLDEVSPRYLQALLAYEDRRFYYHPGVNP 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 121 SGVGRAVIANVVSGAKAQGASTITMQVARnfyLS--SEKSFIRKFYELMLTYKIEQNLSKDQILELYLNQIYLGHRSYGF 198
Cdd:COG4953 98 LALLRAAWQNLRSGRIVSGGSTLTMQVAR---LLepRPRTLSGKLRQILRALQLERRYSKDEILELYLNLAPYGGNIEGV 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 199 AAASRTYYGKPLSEVSIAEAALLAGIPKAPSRFNPRANLKRAVARQHYVLDRMEKLGYITPEQHQEALAQKIVLRdnTQE 278
Cdd:COG4953 175 EAASLAYFGKPPSRLSLAEAALLAVLPQAPSRRRPDRNPERARAARDRVLARLAEAGVIDAEEAALALLEPVPAR--RRP 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 279 TPEttFARHgqyvaeLARQLMynvykdNVYGRGLSVYTTIRSQDQEVAYHAVRDgimsYTRRkpypgpaaqvdlpagien 358
Cdd:COG4953 253 LPQ--LAPH------LARRLL------RQLPGGTRIRTTLDAGLQRRLERLVRR----YVRR------------------ 296
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 359 nterfdLALEEIRNkyrdsddlvTAVVLsasaskvvaartpeqiyelsgkslgyvkraltnsgptsrriqrgsviylqkV 438
Cdd:COG4953 297 ------LKQNGIHN---------AAVLV---------------------------------------------------V 310
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 439 DNtwtiinmptvegafislnpQNGAIESMIGGFDFN---RGDFNRVTQAWRQPGSTFKPFVYAAGLERG-VTPGTNISDQ 514
Cdd:COG4953 311 DN-------------------RTGEVLAYVGSADFFdasRQGQVDMVRALRSPGSTLKPFLYGLALDQGlIHPETLLADV 371
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 515 PfhlsaaqTRSKPWSPKNYGNSYSYSQTMRQGLYKSKNMVSIRILQTVGPEFASEFISRFGFDPaRQPPKSAY-LTMALG 593
Cdd:COG4953 372 P-------TSFGGYRPENFDGTFQGPVSAREALARSLNIPAVRLLEALGPARFYARLRRAGLRL-LLPPAEHYgLSLILG 443
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 594 AGSVTPLQMASAYSVFANGGYRVNPYIIdsvvdistgrvimKAQPAMAGdeaNRVLDPRTAYVMNDLLRGVAKSGTAART 673
Cdd:COG4953 444 GAEVTLEELVGLYAALARGGEARPLRLL-------------AGEPASPG---RRLLSPGAAWLVRDILSDVPRPDGAFGW 507
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 674 QATLKRGDIGGKTGTtnqSY---DAWFAGFTPK-LVGIsWLG-FD-QP-KSLgdkeTGGGAAMPIWLSYMQtALKKVPVT 746
Cdd:COG4953 508 RALDSPPPIAWKTGT---SYgfrDAWAVGFTGRyTVGV-WVGnPDgTPvPGL----TGAEAAAPLLFDIFD-LLPASRWP 578
|
730
....*....|..
gi 754694470 747 PPGPIPEGLAKV 758
Cdd:COG4953 579 LPFPPPAGLLRV 590
|
|
| Transgly |
pfam00912 |
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of ... |
76-252 |
1.44e-83 |
|
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.
Pssm-ID: 459993 [Multi-domain] Cd Length: 177 Bit Score: 264.00 E-value: 1.44e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 76 DKILLAEYGEERRNVLRFNEIPDVMKHALLAAEDDNFYNHGGVDWSGVGRAVIANVVSGAKAQGASTITMQVARNFYLSS 155
Cdd:pfam00912 1 DGTLLAELGEENREYVPLDDIPPALKNAVLAIEDRRFYEHGGVDPKGIARALLSNLRSGRIVQGGSTITQQLAKNLFLTP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 156 EKSFIRKFYELMLTYKIEQNLSKDQILELYLNQIYLGHRSYGFAAASRTYYGKPLSEVSIAEAALLAGIPKAPSRFNPRA 235
Cdd:pfam00912 81 ERTLTRKLKEAVLALKLERRYSKDEILEAYLNTVYFGRGAYGIEAAARAYFGKDASDLTLAEAALLAGLPQAPSRYNPLR 160
|
170
....*....|....*..
gi 754694470 236 NLKRAVARQHYVLDRME 252
Cdd:pfam00912 161 NPERAKRRRNLVLDRMV 177
|
|
| mrcB |
PRK09506 |
bifunctional glycosyl transferase/transpeptidase; Reviewed |
78-762 |
5.61e-72 |
|
bifunctional glycosyl transferase/transpeptidase; Reviewed
Pssm-ID: 236544 [Multi-domain] Cd Length: 830 Bit Score: 252.38 E-value: 5.61e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 78 ILLAEYGEERRNVLRfNEIPDVMKHALLAAEDDNFYNHGGVDWSGVGRAVIANVVSGAKAQGASTITMQVARNFYLSSEK 157
Cdd:PRK09506 202 MLQSPNGEQRLFVPR-SGFPDLLVDTLLATEDRHFYEHDGISLYSIGRAVLANLTAGRTVQGGSTLTQQLVKNLFLSNER 280
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 158 SFIRKFYELMLTYKIEQNLSKDQILELYLNQIYLGHRS----YGFAAASRTYYGKPLSEVSIAEAALLAGIPKAPSRFNP 233
Cdd:PRK09506 281 SLWRKANEAYMALIMDARYSKDRILELYLNEVYLGQSGddqiRGFPLASLYYFGRPVEELSLDQQALLVGMVKGASLYNP 360
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 234 RANLKRAVARQHYVLDRMEKLGYITPEQHQEALAQKI-VLRDNTQETPETTFarhgqyvAELARQLMYNVYKDNVYG-RG 311
Cdd:PRK09506 361 WRNPKLALERRNLVLRLLQQQQIIDQELYDMLSARPLgVQPKGGVISPQPAF-------MQMVRQELQAKLGDKVKDlSG 433
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 312 LSVYTTIRSQDQEVAYHAVRDGImsytrrkpypgPAAQvdlpagiennterfdlaleeirnKYRDSDDLVTAVVLsasas 391
Cdd:PRK09506 434 VKIFTTLDPVSQDAAEKAVEEGI-----------PALK-----------------------KQRKLSDLETAMVV----- 474
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 392 kvvaartpeqiyelsgkslgyvkraltnsgptsrrIQRGSviylqkvdntwtiinmptvegafislnpqnGAIESMIGGF 471
Cdd:PRK09506 475 -----------------------------------VDRFS------------------------------GEVRAMVGGS 489
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 472 DFNRGDFNRVTQAWRQPGSTFKPFVYAAGLERGVTPGTN--ISDQPFHLSaaQTRSKPWSPKNYGNSYSYSQTMRQGLYK 549
Cdd:PRK09506 490 EPQFAGYNRAMQARRSIGSLAKPATYLTALSQPDKYRLNtwIADAPISLR--QPNGQVWSPQNDDRRFSGRVMLVDALTR 567
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 550 SKNMVSIRILQTVGPEFASEFISRFGFDPARQPPKSAyltMALGAGSVTPLQMASAYSVFANGGYRVNPYIIDSVVDiST 629
Cdd:PRK09506 568 SMNVPTVNLGMALGLPAVTDTWIKLGVPKDQLNPVPA---MLLGALNLTPIEVAQAFQTIASGGNRAPLSALRSVIA-ED 643
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 630 GRVIMKAQPamagdEANRVLDPRTAYVMNDLLRGVAKSGTAARTQATLKRGDIGGKTGTTNQSYDAWFAGFTPKLVGISW 709
Cdd:PRK09506 644 GKVLYQSFP-----QAERAVPAQAAYLTLYTMQQVVQRGTGRQLGAKYPNLHLAGKTGTTNDLVDSWFAGIDGKEVTITW 718
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*..
gi 754694470 710 LGFD--QPKSLgdkeTGGGAAMPIWLSYM--QTALKKVPVTPPGPIPEGLAKVGdNF 762
Cdd:PRK09506 719 VGRDnnQPTKL----YGASGAMTIYQRYLenQTPTPLNLTPPEDIVDMGVDYDG-NF 770
|
|
| PBP_1c |
TIGR02073 |
penicillin-binding protein 1C; This subfamily of the penicillin binding proteins includes the ... |
69-753 |
1.17e-66 |
|
penicillin-binding protein 1C; This subfamily of the penicillin binding proteins includes the member from E. coli designated penicillin-binding protein 1C. Members have both transglycosylase and transpeptidase domains and are involved in forming cross-links in the late stages of peptidoglycan biosynthesis. All members of this subfamily are presumed to have the same basic function. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273954 [Multi-domain] Cd Length: 727 Bit Score: 235.78 E-value: 1.17e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 69 PLRVYTADKillaeygEERRNVLRFNEIPDVMKHALLAAEDDNFYNHGGVDWSGVGRAVIANVVSGAKAQGASTITMQVA 148
Cdd:TIGR02073 21 LLRALLAND-------GQWRLPVPLEDISPKFLQALLLYEDKRFYWHPGVNPLALLRAAWQNLTNGRRVSGGSTLTMQLA 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 149 RNFYLSSEKSFIRKFYELMLTYKIEQNLSKDQILELYLNQIYLGHRSYGFAAASRTYYGKPLSEVSIAEAALLAGIPKAP 228
Cdd:TIGR02073 94 RLLDPELSRTLTGKLRQMWRAIQLEARYSKREILEAYLNLAPYGGNLEGLRAASLIYFGKEPSSLSLAEAALLAALPQAP 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 229 SRFNPRANLKRAVARQHYVLDRMEKLGYITPEQHQEALAQKIVLRDNtqETPetTFARHgqYVAELARQlmynvYKDNVY 308
Cdd:TIGR02073 174 SARRLDRLPKAAKAARDRLLDRMVEQGPDDSEQVALAALEPLPALPE--PLP--QLAPH--FALKLLRA-----RPEIAS 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 309 grglSVYTTIRSQDQEVAYHAVRDgimsYTRRKPypgpaaqvdlPAGIENnterfdlaleeirnkyrdsddlvTAVVLsa 388
Cdd:TIGR02073 243 ----VIVSTLDADLQRRLEELARR----YLSALR----------PRGISN-----------------------LAILV-- 279
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 389 saskvvaartpeqiyelsgkslgyvkraltnsgptsrriqrgsviylqkVDNtwtiinmptvegafislnpQNGAIESMI 468
Cdd:TIGR02073 280 -------------------------------------------------VDN-------------------RSGAVLAYV 291
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 469 GGFDFNRGD-FNRV--TQAWRQPGSTFKPFVYAAGLERG-VTPGTNISDQPFHLSAAQtrskpwsPKNYGNSYSYSQTMR 544
Cdd:TIGR02073 292 GSADFFDDSnSGQVdgVRAPRSPGSTLKPFLYALALDDGlLHPDSLLKDVPLRFGDYA-------PENFDKTFHGPVPAR 364
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 545 QGLYKSKNMVSIRILQTVGPEFASEFISRFGFDPARqpPKSAY--LTMALGAGSVTPLQMASAYSVFANGGYRVNPYIId 622
Cdd:TIGR02073 365 EALARSLNIPAVRLLERVGPPRFADFLRQAGLNLLK--PKSDYygLSLALGGAEITLQDLANLYAMLANQGLSGPLRFL- 441
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 623 svvdistgrvimkaQPAMAGDEANRVLDPRTAYVMNDLLRGVAKSGTAARTQATLKRGDIGGKTGTTNQSYDAWFAGFTP 702
Cdd:TIGR02073 442 --------------QTDAKRPERERLLSPGAAWIVLDILKDRPRPDDTLPLSALPTRLPLAWKTGTSYGFRDAWAAGVSG 507
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|...
gi 754694470 703 KLVGISWLG-FD-QPKSlgdKETGGGAAMPIWLSYMQTALKKVPVTPPGPIPE 753
Cdd:TIGR02073 508 RYTIGVWVGnFDgKPNP---GFFGAAAAAPLLFDILDALQASEASTLPRPLKE 557
|
|
| PRK14850 |
PRK14850 |
penicillin-binding protein 1b; Provisional |
78-737 |
1.21e-66 |
|
penicillin-binding protein 1b; Provisional
Pssm-ID: 237835 [Multi-domain] Cd Length: 764 Bit Score: 236.28 E-value: 1.21e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 78 ILLAEYGEERRNVLRfNEIPDVMKHALLAAEDDNFYNHGGVDWSGVGRAVIANVVSGAKAQGASTITMQVARNFYLSSEK 157
Cdd:PRK14850 148 MLYSPEGKKRLFIPR-NQYPEMLIKTLLAIEDKYFYEHDGIHLSSIGRAFLVNLMSGHTIQGGSTLTQQLVKNLFLTNTR 226
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 158 SFIRKFYELMLTYKIEQNLSKDQILELYLNQIYLGH----RSYGFAAASRTYYGKPLSEVSIAEAALLAGIPKAPSRFNP 233
Cdd:PRK14850 227 SLWRKINEIYMALILDRFYSKDRILELYLNEVYLGQdgneQIRGFPLASIYYFGRPINELNLDQYALLVGMVKGASLYNP 306
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 234 RANLKRAVARQHYVLDRMEKLGYITPEQHQEALAQKIvlrdNTQETPETTFARHG--QYVAELARQLMYNVYKDNvygRG 311
Cdd:PRK14850 307 WTNPNLTLKRRNLVLFLLYKQKVITRKLYKDLCSRPL----NVQSKGNIISSHPAfiQLVCEEFHKKIHYPFKNF---SG 379
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 312 LSVYTTIRSQDQEVAYHAVRDGImsytrrkpypgpaaqvdlpagiennterfdlalEEIRNKYRDSDdlvtavvlsasas 391
Cdd:PRK14850 380 TKIFTTLDYISQNAAEQAVKIGI---------------------------------PILKRKKRLKD------------- 413
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 392 kvvaartpeqiyelsgkslgyvkraltnsgptsrriqrgsviylqkvdntwtiinmptVEGAFISLNPQNGAIESMIGGF 471
Cdd:PRK14850 414 ----------------------------------------------------------LEVAMVIIDRFSGEVRALIGSS 435
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 472 DFNRGDFNRVTQAWRQPGSTFKPFVYAAGLERgvtP-----GTNISDQPFHLSaaQTRSKPWSPKNYGNSYSYSQTMRQG 546
Cdd:PRK14850 436 KPEFNGYNRALKARRSIGSLSKPITYLTALSQ---PekyhlNTWISDTPISIK--LDNGQYWTPKNNNFSFSGKVMLIDA 510
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 547 LYKSKNMVSIRILQTVGPEFASEFISRFGFDPARQPPksaYLTMALGAGSVTPLQMASAYSVFANGGYRVNPYIIDSVVD 626
Cdd:PRK14850 511 LIHSINIPTVHLSINLGLKKLVDSWILLGISSNYITP---LPSISLGAINLTPMEVAQVFQIIGSGGYKSSLSSIRSIIS 587
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 627 iSTGRVIMKAQPamagdEANRVLDPRTAYVMNDLLRGVAKSGTAARTQATLKRGDIGGKTGTTNQSYDAWFAGFTPKLVG 706
Cdd:PRK14850 588 -DDNKVLYQNFP-----QSKHVESSQASYLTLYAMQQVVKSGTAKSLGTIFKEFSLAGKTGTTNNLVDSWFVGIDGKQVV 661
|
650 660 670
....*....|....*....|....*....|.
gi 754694470 707 ISWLGFDQPKSlgDKETGGGAAMPIWLSYMQ 737
Cdd:PRK14850 662 ITWIGRDNNHT--TKLYGSSGAMKIYKRYLQ 690
|
|
| PRK13481 |
PRK13481 |
glycosyltransferase; Provisional |
85-268 |
1.47e-40 |
|
glycosyltransferase; Provisional
Pssm-ID: 184078 [Multi-domain] Cd Length: 232 Bit Score: 149.18 E-value: 1.47e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 85 EERRNVLRFNEIPDVMKHALLAAEDDNFYNHGGVDWSGVGRAVIANVvSGAKAQGASTITMQVARNFYLSSEKSFIRKFY 164
Cdd:PRK13481 42 ENKSSFVSADNMPEYVKGAFISMEDERFYKHHGFDLKGTTRALFSTI-SDRDVQGGSTITQQVVKNYFYDNERSFTRKVK 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 165 ELMLTYKIEQNLSKDQILELYLNQIYLGHRSYGFAAASRTYYG-------KPLSEVSIAEAALLAGIPKAPSRFNPRANL 237
Cdd:PRK13481 121 ELFVAHRVEKQYSKNEILSFYLNNIYFGDNQYTLEGAANHYFGttvnknsTTMSHITVLQSAILASKVNAPSVYNINDMS 200
|
170 180 190
....*....|....*....|....*....|.
gi 754694470 238 KRAVARQHYVLDRMEKLGYITPEQHQEALAQ 268
Cdd:PRK13481 201 ENFTQRVSTNLEKMKQQNYINETQYQQAMSQ 231
|
|
| FtsI |
COG0768 |
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell ... |
452-742 |
4.97e-40 |
|
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell cycle control, cell division, chromosome partitioning, Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440531 [Multi-domain] Cd Length: 568 Bit Score: 156.14 E-value: 4.97e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 452 GAFISLNPQNGAIESMIG--GFD---FNRGD----FNRVTQAWRQPGSTFKPFVYAAGLERGV-TPGTNISDqPFHLSAA 521
Cdd:COG0768 249 GAVVVMDPKTGEILAMASypSFDpnlFVGGPdeplRNRAVQGTYEPGSTFKPFTAAAALEEGViTPDTTFDC-PGYYRVG 327
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 522 QTRSKPWSPKNYGNsysysQTMRQGLYKSKNMVSIRILQTVGPEFASEFISRFGFD---------------PARQP-PKS 585
Cdd:COG0768 328 GRTIRDWDRGGHGT-----LTLTEALAKSSNVGFYKLALRLGIDKLYDYLKKFGLGqktgidlpgeasgllPSPKRwYPG 402
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 586 AYLTMALGAG-SVTPLQMASAYSVFANGGYRVNPYIIDSVVDiSTGRVIMKAQPamagdEANRVLDPRTAYVMNDLLRGV 664
Cdd:COG0768 403 ETATMSIGQGlSVTPLQLAQAYAAIANGGVLVKPHLVKEIVD-PDGEVVKEEPE-----VLRRVISPETAETVREGMEGV 476
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 665 AKS--GTAARtqATLKRGDIGGKTGT-----------TNQSYDAWFAGFTPK-------LVGIswlgfDQPKSlgdKETG 724
Cdd:COG0768 477 VNEpgGTARR--AAIPGYRVAGKTGTaqvvdignggyYKGRHIASFVGFAPAdnpryavAVVV-----ENPGG---GAYG 546
|
330
....*....|....*...
gi 754694470 725 GGAAMPIWLSYMQTALKK 742
Cdd:COG0768 547 GTVAAPVFREIMEAYLRL 564
|
|
| Transpeptidase |
pfam00905 |
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss: ... |
452-703 |
7.46e-38 |
|
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss:P14677) is conserved in all members of this family.
Pssm-ID: 425939 [Multi-domain] Cd Length: 296 Bit Score: 143.33 E-value: 7.46e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 452 GAFISLNPQNGAIESMIGGFDFNRGDF-----NRVTQAWRQPGSTFKPFVYAAGLERGV-TPGTNISDQPFHlsaaQTRS 525
Cdd:pfam00905 1 GSAVVLDPKTGEVLAMVGKPSYDPNGFigplrNRAVTSRYEPGSTFKPFTALAALDNGVlKPDETIFDWPGK----QQGG 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 526 KPWspKNYGNSYSYSQTMRQGLYKSKNMVSIRILQTVGPEFASEFISRFGF-------DPAR-----QPPKSAYLTMALG 593
Cdd:pfam00905 77 KSI--GDWNQDQVGIGTLRQALEYSSNWYMQKLAQKLGADKLRSYLKKFGYgnktgigLPGEnagylTPYWLEGATASFG 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 594 AG-SVTPLQMASAYSVFANGGYRVNPYIIDSVVDISTGRVIMKaqpamagdeanRVLDPRTAYVMNDLLRGVAKSGTAAR 672
Cdd:pfam00905 155 IGlTITPLQQAQAYAAIANGGKLVPPHLVKSIEDKVDPKVLNK-----------LPISKSTAEKVKDMLRLVVNDGTGTG 223
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 754694470 673 TQATLKRgDIGGKTGTT-----------NQSYDAWFAGFTPK 703
Cdd:pfam00905 224 TAAVPGY-KVAGKTGTAqvagpkgggyyDGAQIGWFVGYAPA 264
|
|
| PRK11240 |
PRK11240 |
penicillin-binding protein 1C; Provisional |
103-711 |
2.44e-36 |
|
penicillin-binding protein 1C; Provisional
Pssm-ID: 183049 [Multi-domain] Cd Length: 772 Bit Score: 147.15 E-value: 2.44e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 103 ALLAAEDDNFYNHGGVDWSGVGRAVIANVVSGAKAQGASTITMQVARnFYLSSEKSFIRKFYELMLTYKIEQNLSKDQIL 182
Cdd:PRK11240 77 ALINYEDRWFWKHPGVNPFSVARAAWQDLTSGRVISGGSTLTMQVAR-LLDPHPRTFGGKIRQLWRALQLEWHLSKREIL 155
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 183 ELYLNQIYLGHRSYGFAAASRTYYGKPLSEVSIAEAALLAGIPKAPSRFNPRANLKRAVARQHYVLDRMEKLGYITPEQH 262
Cdd:PRK11240 156 TLYLNRAPFGGTLQGIGAASWAYLGKSPANLSYAEAALLAVLPQAPSRLRPDRWPERAEAARNKVLERMAEQGVWSAEQV 235
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 263 QEALAQKIVLrdntqetpettFARHGQYVAELARQLMYNVYKDNVygrglsVYTTirsqdqevayhavrdgimsytrrkp 342
Cdd:PRK11240 236 KESREEPVWL-----------APRQMPQLAPLFARMMLGKSKSDK------IVTT------------------------- 273
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 343 ypgpaaqvdLPAGIENNTErfDLALEEirnKYRdsddlvtavvlsasaskvVAARTpeqiyelsgkSLGYVkraltnsgp 422
Cdd:PRK11240 274 ---------LDAGLQRRLE--DLALNW---KGR------------------LPPRS----------SLAMI--------- 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 423 tsrriqrgsviylqKVDNTwtiiNMptvegafislnpqngAIESMIGGFDFNR----GDFNRVTqAWRQPGSTFKPFVYA 498
Cdd:PRK11240 303 --------------VVDHT----DM---------------AVRGWVGSVDLNDdsrfGHVDMVN-AIRSPGSVLKPFVYG 348
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 499 AGLERG-VTPGTNISDQPfhlsaaqTRSKPWSPKNYGNSYSYSQTMRQGLYKSKNMVSIRILQTVGPE-FASEFisRFGF 576
Cdd:PRK11240 349 LALDDGlIHPASLLQDVP-------RRTGDYRPGNFDSGFHGPVSMSEALVRSLNLPAVQVLEAYGPKrFAAKL--RNVG 419
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 577 DPARQPPKSA-YLTMALGAGSVTPLQMASAYSVFANGG----YRVNPYiiDSVVDistgrvimkaqpamagdeaNRVLDP 651
Cdd:PRK11240 420 LPLYLPAGAEpNLSLILGGAGARLEDMVAAYSAFARHGkaakLRLQPD--DPLLE-------------------RPLMSP 478
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 754694470 652 RTAYVMNDLLRGVAKSGTAArtqATLKRGDIGGKTGTTNQSYDAWFAGFTPK-LVGIsWLG 711
Cdd:PRK11240 479 GAAWIIRRIMADEAQPLPDA---ALPRVVPLAWKTGTSYGYRDAWAIGVNARyVIGI-WTG 535
|
|
| pbp2_mrdA |
TIGR03423 |
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 ... |
452-731 |
9.26e-27 |
|
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 (PBP-2), a protein whose gene (designated pbpA or mrdA) generally is found next to the gene for RodA, a protein required for rod (bacillus) shape in many bacteria. PBP-2 acts as a transpeptidase for cell elongation (hence, rod-shape). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 274573 [Multi-domain] Cd Length: 592 Bit Score: 116.08 E-value: 9.26e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 452 GAFISLNPQNGAIESMIG--GFD---FNRG-----------D-----FNRVTQAWRQPGSTFKPFVYAAGLERGV-TPGT 509
Cdd:TIGR03423 249 GAVVVMDPRTGEILAMVStpSFDpnlFVDGisskdykallnDpdrplLNRAIQGVYPPGSTFKPVVALAALEEGViTPET 328
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 510 NISDqPFHLSAAQTRSKPWSPKNYGnsysySQTMRQGLYKSKNMVSIRILQTVGPEFASEFISRFGF------D------ 577
Cdd:TIGR03423 329 RIYC-PGYFQLGGRRFRCWKRGGHG-----RVDLRKAIEESCDVYFYQLALRLGIDKIAEYAKRFGFgqktgiDlpgeks 402
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 578 ---PARQPPKSAY---------LTMALGAG--SVTPLQMASAYSVFANGGYRVNPYIIDSVVDiSTGRVIMKAQPAMAGD 643
Cdd:TIGR03423 403 glvPSREWKRKRFgqpwypgdtLNVSIGQGyvLVTPLQLAVATAALANGGKLYKPHLVKSIED-PDGGVVRRTEPEVLRP 481
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 644 eanRVLDPRTAYVMNDLLRGVAKS--GTAARTQATLKrGDIGGKTGT-------TNQSYD-----------AWFAGFTPk 703
Cdd:TIGR03423 482 ---LPISPENLDVVREGMRDVVNGpgGTARRARLGLP-YKMAGKTGTaqvvslkQGEKYDaeqiperlrdhALFVAFAP- 556
|
330 340 350
....*....|....*....|....*....|...
gi 754694470 704 lvgiswlgFDQPK-----SLGDKETGGGAAMPI 731
Cdd:TIGR03423 557 --------YDNPKiavavIVEHGGGGSSAAAPI 581
|
|
| PCB_OB |
pfam17092 |
Penicillin-binding protein OB-like domain; |
343-450 |
3.56e-17 |
|
Penicillin-binding protein OB-like domain;
Pssm-ID: 465343 [Multi-domain] Cd Length: 111 Bit Score: 77.68 E-value: 3.56e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 343 YPGPAAQVDLPAGIENNTERFDLALEEirnkYRDSDDLVTAVVLSASASKVVAARTPEQIYELSGKSLGYVKRALTNS-- 420
Cdd:pfam17092 1 YRGPEAHLDLPADWAERLAAIDEALAD----LPDVGGLRPAVVLSVSPKSARVGLRDGETGTIPGEGLRWARPYLSDKrq 76
|
90 100 110
....*....|....*....|....*....|....*
gi 754694470 421 GPT----SRRIQRGSVIYLQKV-DNTWTIINMPTV 450
Cdd:pfam17092 77 GPApksaSDVLKPGDVIRVRPNgDGGWRLRQVPEV 111
|
|
| PRK10795 |
PRK10795 |
penicillin-binding protein 2; Provisional |
400-695 |
3.43e-07 |
|
penicillin-binding protein 2; Provisional
Pssm-ID: 236761 [Multi-domain] Cd Length: 634 Bit Score: 54.00 E-value: 3.43e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 400 EQIYE--LSGKSlGYVKRALTNSGPTSRRI-----QRGSVIYLQKVDNTWTIIN--MPTVEGAFISLNPQNGAIESMI-- 468
Cdd:PRK10795 212 ERYYEdvLHGKT-GYEEVEVNNRGRVIRQLheqppQAGHDIYLTLDLKLQQYIEtlLAGSRAAVVVTDPRTGGILALVst 290
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 469 ---------GGF----------DFNRGDFNRVTQAWRQPGSTFKPFVYAAGLERGV-TPGTNISDqP--FHLSAAQTRSK 526
Cdd:PRK10795 291 psydpnlfvDGIsskdysgllnDPNRPLINRATQGVYPPASTVKPYVAVSALSAGViTRNTSLFD-PgwWQLPGSEKRYR 369
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 527 PWspKNYGNSysySQTMRQGLYKSKNMVSIRILQTVGPEFASEFISRFGFD---------------PARQPPKSAYL--- 588
Cdd:PRK10795 370 DW--KKWGHG---RLNVTKSLEESADTFFYQVAYDMGIDRLSEWMGKFGYGhytgidlaeersgnmPTREWKQKRFKkpw 444
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 589 ----TMALGAG----SVTPLQMASAYSVFANGGYRVNPYIIDSVVDisTGRVIMKAQPamagdEANRVLDPRTAY--VMN 658
Cdd:PRK10795 445 yqgdTIPVGIGqgywTATPIQMSKALMTLINDGIVKVPHLLMSTAE--DGKQVPWVQP-----HEPPVGDIHSGYweIAK 517
|
330 340 350 360
....*....|....*....|....*....|....*....|....*.
gi 754694470 659 DLLRGVAK--SGTAARTQATLKRgDIGGKTGT-------TNQSYDA 695
Cdd:PRK10795 518 DGMYGVANrpNGTAHKYFASAPY-KIAAKSGTaqvfglkANETYNA 562
|
|
| PRK15105 |
PRK15105 |
peptidoglycan synthase FtsI; Provisional |
479-747 |
1.06e-04 |
|
peptidoglycan synthase FtsI; Provisional
Pssm-ID: 185060 [Multi-domain] Cd Length: 578 Bit Score: 45.58 E-value: 1.06e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 479 NRVTQAWRQPGSTFKPFVYAAGLERG-VTPGTNISDQPFHLSAAQTRskpwspknygNSYSYSQTMRQG-LYKSKNmVSI 556
Cdd:PRK15105 295 NRAITDVFEPGSTVKPMVVMTALQRGvVKENSVLNTVPYRINGHEIK----------DVARYSELTLTGvLQKSSN-VGV 363
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 557 RILQTVGPefASEFI---SRFGFDPARQ-----------PPKSAY-----LTMALGAG-SVTPLQMASAYSVFANGG-YR 615
Cdd:PRK15105 364 SKLALAMP--SSALVdtySRFGLGKATNlglvgersglyPQKQRWsdierATFSFGYGlMVTPLQLARVYATIGSYGiYR 441
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 616 vnpyiidsvvDIStgrvIMKAQPAMAGDeanRVLDPRTAYVMNDLLRGVAKSGTAArTQATLKRGDIGGKTGTTNQ---- 691
Cdd:PRK15105 442 ----------PLS----ITKVDPPVPGE---RVFPESIVRTVVHMMESVALPGGGG-VKAAIKGYRIAIKTGTAKKvgpd 503
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 754694470 692 -----SYDAWFAGFTP------KLVGIswlgFDQPKslGDKETGGGAAMPIWLSYMQTALKKVPVTP 747
Cdd:PRK15105 504 gryinKYIAYTAGVAPasqprfALVVV----INDPQ--AGKYYGGAVSAPVFGAIMGGVLRTMNIEP 564
|
|
| FAM216B |
pfam15107 |
FAM216B protein family; The function of this family of proteins, FAM216B, has not, as yet, ... |
214-287 |
1.32e-03 |
|
FAM216B protein family; The function of this family of proteins, FAM216B, has not, as yet, been determined. Members of this family are as yet uncharacterized. This family of proteins are found in eukaryotes. Proteins in this family are approximately 150 amino acids in length. In humans, the gene encoding this protein is located in the position, C13orf30.
Pssm-ID: 434464 Cd Length: 111 Bit Score: 39.03 E-value: 1.32e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754694470 214 SIAEAALLAGIPKAPSRF--------NPRAnLKRAVARQH-YVLDRMEKLGYITpeqHQEALAQKIVLRDNT-QETPETT 283
Cdd:pfam15107 25 SASDTSLLKDLTQGQQRYlysimkiyNSRP-QWEALKRRYiHSLQHQQLLGYIT---QHEALACSAVLRDSTkRASAKTA 100
|
....
gi 754694470 284 FARH 287
Cdd:pfam15107 101 WRRT 104
|
|
| |
