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Conserved domains on  [gi|767168213|gb|AJS44357|]
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Bas1p [Saccharomyces cerevisiae YJM1307]

Protein Classification

REB1 family protein( domain architecture ID 11473979)

REB1 family protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
REB1 COG5147
Myb superfamily proteins, including transcription factors and mRNA splicing factors ...
 17-585 1.98e-154

Myb superfamily proteins, including transcription factors and mRNA splicing factors [Transcription / RNA processing and modification / Cell division and chromosome partitioning];


:

Pssm-ID: 227476 [Multi-domain]  Cd Length: 512  Bit Score: 460.79  E-value: 1.98e-154
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767168213  17 GSGFDLLEVTESLgYQTHRKNGrnSWSKDDDNMLRSLVnesaKELGYENgledvktiqqsnhlskciaWDVLATRFKHtv 96
Cdd:COG5147    1 DTSLHNKELQIKL-MQTKRKGG--SWKRTEDEDLKALV----KKLGPNN-------------------WSKVASLLIS-- 52

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767168213  97 RTSKDVRKRWTGSLDPNLKKGKWTQEEDEQLLKAYEEHGPHWLSISMDIPGRTEDQCAKRYIEVLGPGSKgrlREWTLEE 176
Cdd:COG5147   53 STGKQSSNRWNNHLNPQLKKKNWSEEEDEQLIDLDKELGTQWSTIADYKDRRTAQQCVERYVNTLEDLSS---THDSKLQ 129

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767168213 177 DLNLISKVKAYGTKWRKISSEMEFRPSLTCRNRWRKIITMVVRGQASEVITKAIKENKNIDMTDGKLRQHPIADSDIRSD 256
Cdd:COG5147  130 RRNEFDKIDPFNENSARRPDIYEDELLEREVNREASYRLRVPRVSKADVKPREKGEENNPDIEDLQEMKELKSASITRHL 209

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767168213 257 STPNKEEQlqlsqqnnPSLIKQDILNVKENESSKLPRLKDNDGPILNDSKPQALppLKEISAPPPIRMTQVSQPHTSGSI 336
Cdd:COG5147  210 ILPSKSEI--------NKAFKKGETLALEQEINEYKEKKGLSRKQFCERIWSTD--RDEDKFWPNIYKKLPYRDKKSIYK 279

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767168213 337 RSKVSLPIEGLSQMNKQSPGGISDSPQTSLPPAFNPASLDEHMMNSNSIsdspkHAYSTVKTREpnssstqwkFTLKDGQ 416
Cdd:COG5147  280 HLRRKYNIFEQRGKWTKEEEQELAKLVVEHGGSWTEIGKLLGRMPNDCR-----DRWRDYVKCG---------DTLKRNR 345

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767168213 417 GLSISNGTIDSTKLVKELVDQAKKYSLKISIHQHIHNHYVTSTDHPVSSNTGLSNIGNINGNPLLMDSFPHMGRQLGNGL 496
Cdd:COG5147  346 WSIEEEELLDKVVNEMRLEAQQSSRILWLLIAQNIRNRLQHHCRDKYGVLISNSSPFDAGAAIWLIERYSNRKIQNGDLI 425

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767168213 497 PGLNSNSDTFNPEYRTSLDNMDSDFLSRTPNSNAFSLEATSHNPADNANELGSQSNRETNSPsvFYPQANTLIPTNSTAT 576
Cdd:COG5147  426 KWRNSVLDSARRRMRDLKDLPEYALLLRTPDYNKSSLERIKKSAIDDGKKVLSLTLRELNKE--SSPERNYISDFKDSAT 503


                 ....*....
gi 767168213 577 NNEIIQGNV 585
Cdd:COG5147  504 AFIIIQRLC 512
 
Name Accession Description Interval E-value
REB1 COG5147
Myb superfamily proteins, including transcription factors and mRNA splicing factors ...
 17-585 1.98e-154

Myb superfamily proteins, including transcription factors and mRNA splicing factors [Transcription / RNA processing and modification / Cell division and chromosome partitioning];


Pssm-ID: 227476 [Multi-domain]  Cd Length: 512  Bit Score: 460.79  E-value: 1.98e-154
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767168213  17 GSGFDLLEVTESLgYQTHRKNGrnSWSKDDDNMLRSLVnesaKELGYENgledvktiqqsnhlskciaWDVLATRFKHtv 96
Cdd:COG5147    1 DTSLHNKELQIKL-MQTKRKGG--SWKRTEDEDLKALV----KKLGPNN-------------------WSKVASLLIS-- 52

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767168213  97 RTSKDVRKRWTGSLDPNLKKGKWTQEEDEQLLKAYEEHGPHWLSISMDIPGRTEDQCAKRYIEVLGPGSKgrlREWTLEE 176
Cdd:COG5147   53 STGKQSSNRWNNHLNPQLKKKNWSEEEDEQLIDLDKELGTQWSTIADYKDRRTAQQCVERYVNTLEDLSS---THDSKLQ 129

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767168213 177 DLNLISKVKAYGTKWRKISSEMEFRPSLTCRNRWRKIITMVVRGQASEVITKAIKENKNIDMTDGKLRQHPIADSDIRSD 256
Cdd:COG5147  130 RRNEFDKIDPFNENSARRPDIYEDELLEREVNREASYRLRVPRVSKADVKPREKGEENNPDIEDLQEMKELKSASITRHL 209

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767168213 257 STPNKEEQlqlsqqnnPSLIKQDILNVKENESSKLPRLKDNDGPILNDSKPQALppLKEISAPPPIRMTQVSQPHTSGSI 336
Cdd:COG5147  210 ILPSKSEI--------NKAFKKGETLALEQEINEYKEKKGLSRKQFCERIWSTD--RDEDKFWPNIYKKLPYRDKKSIYK 279

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767168213 337 RSKVSLPIEGLSQMNKQSPGGISDSPQTSLPPAFNPASLDEHMMNSNSIsdspkHAYSTVKTREpnssstqwkFTLKDGQ 416
Cdd:COG5147  280 HLRRKYNIFEQRGKWTKEEEQELAKLVVEHGGSWTEIGKLLGRMPNDCR-----DRWRDYVKCG---------DTLKRNR 345

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767168213 417 GLSISNGTIDSTKLVKELVDQAKKYSLKISIHQHIHNHYVTSTDHPVSSNTGLSNIGNINGNPLLMDSFPHMGRQLGNGL 496
Cdd:COG5147  346 WSIEEEELLDKVVNEMRLEAQQSSRILWLLIAQNIRNRLQHHCRDKYGVLISNSSPFDAGAAIWLIERYSNRKIQNGDLI 425

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767168213 497 PGLNSNSDTFNPEYRTSLDNMDSDFLSRTPNSNAFSLEATSHNPADNANELGSQSNRETNSPsvFYPQANTLIPTNSTAT 576
Cdd:COG5147  426 KWRNSVLDSARRRMRDLKDLPEYALLLRTPDYNKSSLERIKKSAIDDGKKVLSLTLRELNKE--SSPERNYISDFKDSAT 503


                 ....*....
gi 767168213 577 NNEIIQGNV 585
Cdd:COG5147  504 AFIIIQRLC 512
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 116-161 5.33e-13

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 63.68  E-value: 5.33e-13
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 767168213  116 KGKWTQEEDEQLLKAYEEHGPHWLSISMDIPGRTEDQCAKRYIEVL 161
Cdd:pfam00249   1 RGPWTPEEDELLLEAVEKLGNRWKKIAKLLPGRTDNQCKNRWQNYL 46
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
116-163 7.08e-12

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 60.70  E-value: 7.08e-12
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 767168213   116 KGKWTQEEDEQLLKAYEEHGP-HWLSISMDIPGRTEDQCAKRYIEVLGP 163
Cdd:smart00717   1 KGEWTEEEDELLIELVKKYGKnNWEKIAKELPGRTAEQCRERWRNLLKP 49
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 118-161 3.44e-11

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 58.74  E-value: 3.44e-11
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 767168213 118 KWTQEEDEQLLKAYEEHGP-HWLSISMDIPGRTEDQCAKRYIEVL 161
Cdd:cd00167    1 PWTEEEDELLLEAVKKYGKnNWEKIAKELPGRTPKQCRERWRNLL 45
PLN03212 PLN03212
Transcription repressor MYB5; Provisional
 96-152 2.18e-04

Transcription repressor MYB5; Provisional


Pssm-ID: 178751 [Multi-domain]  Cd Length: 249  Bit Score: 43.91  E-value: 2.18e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 767168213  96 VRTSKDVRKRWTGSLDPNLKKGKWTQEEDEQLLKAYEEHGPHWLSISMDIPGRTEDQ 152
Cdd:PLN03212  58 LRCGKSCRLRWMNYLRPSVKRGGITSDEEDLILRLHRLLGNRWSLIAGRIPGRTDNE 114
 
Name Accession Description Interval E-value
REB1 COG5147
Myb superfamily proteins, including transcription factors and mRNA splicing factors ...
 17-585 1.98e-154

Myb superfamily proteins, including transcription factors and mRNA splicing factors [Transcription / RNA processing and modification / Cell division and chromosome partitioning];


Pssm-ID: 227476 [Multi-domain]  Cd Length: 512  Bit Score: 460.79  E-value: 1.98e-154
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767168213  17 GSGFDLLEVTESLgYQTHRKNGrnSWSKDDDNMLRSLVnesaKELGYENgledvktiqqsnhlskciaWDVLATRFKHtv 96
Cdd:COG5147    1 DTSLHNKELQIKL-MQTKRKGG--SWKRTEDEDLKALV----KKLGPNN-------------------WSKVASLLIS-- 52

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767168213  97 RTSKDVRKRWTGSLDPNLKKGKWTQEEDEQLLKAYEEHGPHWLSISMDIPGRTEDQCAKRYIEVLGPGSKgrlREWTLEE 176
Cdd:COG5147   53 STGKQSSNRWNNHLNPQLKKKNWSEEEDEQLIDLDKELGTQWSTIADYKDRRTAQQCVERYVNTLEDLSS---THDSKLQ 129

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767168213 177 DLNLISKVKAYGTKWRKISSEMEFRPSLTCRNRWRKIITMVVRGQASEVITKAIKENKNIDMTDGKLRQHPIADSDIRSD 256
Cdd:COG5147  130 RRNEFDKIDPFNENSARRPDIYEDELLEREVNREASYRLRVPRVSKADVKPREKGEENNPDIEDLQEMKELKSASITRHL 209

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767168213 257 STPNKEEQlqlsqqnnPSLIKQDILNVKENESSKLPRLKDNDGPILNDSKPQALppLKEISAPPPIRMTQVSQPHTSGSI 336
Cdd:COG5147  210 ILPSKSEI--------NKAFKKGETLALEQEINEYKEKKGLSRKQFCERIWSTD--RDEDKFWPNIYKKLPYRDKKSIYK 279

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767168213 337 RSKVSLPIEGLSQMNKQSPGGISDSPQTSLPPAFNPASLDEHMMNSNSIsdspkHAYSTVKTREpnssstqwkFTLKDGQ 416
Cdd:COG5147  280 HLRRKYNIFEQRGKWTKEEEQELAKLVVEHGGSWTEIGKLLGRMPNDCR-----DRWRDYVKCG---------DTLKRNR 345

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767168213 417 GLSISNGTIDSTKLVKELVDQAKKYSLKISIHQHIHNHYVTSTDHPVSSNTGLSNIGNINGNPLLMDSFPHMGRQLGNGL 496
Cdd:COG5147  346 WSIEEEELLDKVVNEMRLEAQQSSRILWLLIAQNIRNRLQHHCRDKYGVLISNSSPFDAGAAIWLIERYSNRKIQNGDLI 425

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767168213 497 PGLNSNSDTFNPEYRTSLDNMDSDFLSRTPNSNAFSLEATSHNPADNANELGSQSNRETNSPsvFYPQANTLIPTNSTAT 576
Cdd:COG5147  426 KWRNSVLDSARRRMRDLKDLPEYALLLRTPDYNKSSLERIKKSAIDDGKKVLSLTLRELNKE--SSPERNYISDFKDSAT 503


                 ....*....
gi 767168213 577 NNEIIQGNV 585
Cdd:COG5147  504 AFIIIQRLC 512
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 116-161 5.33e-13

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 63.68  E-value: 5.33e-13
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 767168213  116 KGKWTQEEDEQLLKAYEEHGPHWLSISMDIPGRTEDQCAKRYIEVL 161
Cdd:pfam00249   1 RGPWTPEEDELLLEAVEKLGNRWKKIAKLLPGRTDNQCKNRWQNYL 46
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
116-163 7.08e-12

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 60.70  E-value: 7.08e-12
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 767168213   116 KGKWTQEEDEQLLKAYEEHGP-HWLSISMDIPGRTEDQCAKRYIEVLGP 163
Cdd:smart00717   1 KGEWTEEEDELLIELVKKYGKnNWEKIAKELPGRTAEQCRERWRNLLKP 49
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 118-161 3.44e-11

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 58.74  E-value: 3.44e-11
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 767168213 118 KWTQEEDEQLLKAYEEHGP-HWLSISMDIPGRTEDQCAKRYIEVL 161
Cdd:cd00167    1 PWTEEEDELLLEAVKKYGKnNWEKIAKELPGRTPKQCRERWRNLL 45
Myb_DNA-bind_6 pfam13921
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 119-180 4.08e-11

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 372817 [Multi-domain]  Cd Length: 60  Bit Score: 58.86  E-value: 4.08e-11
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767168213  119 WTQEEDEQLLKAYEEHGPHWLSISMDIPGRTEDQCAKRYIEVLGPG-SKGrlrEWTLEEDLNL 180
Cdd:pfam13921   1 WTEEEDEKLLKLVEKYGNDWKQIAKELGRRTPKQCFDRWRRKLNPKiSRG---PWSKEEDQRL 60
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 171-212 1.01e-09

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 54.43  E-value: 1.01e-09
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 767168213  171 EWTLEEDLNLISKVKAYGTKWRKISSEMEFRPSLTCRNRWRK 212
Cdd:pfam00249   3 PWTPEEDELLLEAVEKLGNRWKKIAKLLPGRTDNQCKNRWQN 44
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
170-216 2.43e-09

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 53.38  E-value: 2.43e-09
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*...
gi 767168213   170 REWTLEEDLNLISKVKAYGTK-WRKISSEMEFRPSLTCRNRWRKIITM 216
Cdd:smart00717   2 GEWTEEEDELLIELVKKYGKNnWEKIAKELPGRTAEQCRERWRNLLKP 49
SANT_CDC5_II cd11659
SANT/myb-like DNA-binding domain of Cell Division Cycle 5-Like Protein repeat II; In humans, ...
 112-161 3.39e-09

SANT/myb-like DNA-binding domain of Cell Division Cycle 5-Like Protein repeat II; In humans, cell division cycle 5-like protein (CDC5) functions in pre-mRNA splicing in cell cycle control. The DNA-binding, myb-like domain of CDC5 is a member of the SANT/myb group. SANT is named after 'SWI3, ADA2, N-CoR and TFIIIB', several factors that share this domain. The SANT domain resembles the 3 alpha-helix bundle of DNA-binding Myb domains and is found in a diverse set of proteins.


Pssm-ID: 212557 [Multi-domain]  Cd Length: 53  Bit Score: 53.08  E-value: 3.39e-09
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 767168213 112 PNLKKGKWTQEEDEQLLKAYEEHGPHWLSISmDIPGRTEDQCAKRYIEVL 161
Cdd:cd11659    1 PSIKKTEWTREEDEKLLHLAKLLPTQWRTIA-PIVGRTAQQCLERYNKLL 49
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 171-214 3.62e-09

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 52.96  E-value: 3.62e-09
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 767168213 171 EWTLEEDLNLISKVKAYGTK-WRKISSEMEFRPSLTCRNRWRKII 214
Cdd:cd00167    1 PWTEEEDELLLEAVKKYGKNnWEKIAKELPGRTPKQCRERWRNLL 45
Myb_DNA-bind_6 pfam13921
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 172-214 2.27e-08

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 372817 [Multi-domain]  Cd Length: 60  Bit Score: 51.16  E-value: 2.27e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 767168213  172 WTLEEDLNLISKVKAYGTKWRKISSEMEFRPSLTCRNRWRKII 214
Cdd:pfam13921   1 WTEEEDEKLLKLVEKYGNDWKQIAKELGRRTPKQCFDRWRRKL 43
Myb_DNA-bind_6 pfam13921
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 42-127 3.70e-07

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 372817 [Multi-domain]  Cd Length: 60  Bit Score: 47.69  E-value: 3.70e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767168213   42 WSKDDDNMLRSLVNEsakelgYENGLedvktiqqsNHLSKCIAwdvlatrfkhtVRTSKDVRKRWTGSLDPNLKKGKWTQ 121
Cdd:pfam13921   1 WTEEEDEKLLKLVEK------YGNDW---------KQIAKELG-----------RRTPKQCFDRWRRKLNPKISRGPWSK 54


                  ....*.
gi 767168213  122 EEDEQL 127
Cdd:pfam13921  55 EEDQRL 60
PLN03212 PLN03212
Transcription repressor MYB5; Provisional
 96-152 2.18e-04

Transcription repressor MYB5; Provisional


Pssm-ID: 178751 [Multi-domain]  Cd Length: 249  Bit Score: 43.91  E-value: 2.18e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 767168213  96 VRTSKDVRKRWTGSLDPNLKKGKWTQEEDEQLLKAYEEHGPHWLSISMDIPGRTEDQ 152
Cdd:PLN03212  58 LRCGKSCRLRWMNYLRPSVKRGGITSDEEDLILRLHRLLGNRWSLIAGRIPGRTDNE 114
PLN03091 PLN03091
hypothetical protein; Provisional
 114-395 2.25e-04

hypothetical protein; Provisional


Pssm-ID: 215570 [Multi-domain]  Cd Length: 459  Bit Score: 44.58  E-value: 2.25e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767168213 114 LKKGKWTQEEDEQLLKAYEEHGPHWLSISMDIPG--RTEDQCAKRYIEVLGPGSKgrlREWTLEEDLNLISKVKA-YGTK 190
Cdd:PLN03091  12 LRKGLWSPEEDEKLLRHITKYGHGCWSSVPKQAGlqRCGKSCRLRWINYLRPDLK---RGTFSQQEENLIIELHAvLGNR 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767168213 191 WRKISSEMEFRPSLTCRNRWRKIITMVVRGQASEVIT-KAIKENKNidmtdGKLRQHPIADSDIRSDSTPNKEEQL---- 265
Cdd:PLN03091  89 WSQIAAQLPGRTDNEIKNLWNSCLKKKLRQRGIDPNThKPLSEVEN-----GEDKNPPTDDKSDKASSVVSNELNLlkad 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767168213 266 -------QLSQQNNPSLIKQDILNVKENESSKLPRLKDNDGPILNDSKPqalPPLKEISAPppiRMTQVSQPHTSGSIRS 338
Cdd:PLN03091 164 nskplaaLQEKRSSSISPAGYQLEVESSSSSKINNSNNNNHSNSNLMTP---TPNKDFFLD---RFTTSHESSTTSCRPS 237

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767168213 339 KV--SLPiegLSQMNKQSPGGISDSPQTSLppAFNPASLDEHM---MNSNSISDSPKHAYST 395
Cdd:PLN03091 238 DLvgHFP---FQQLNYASNARLSTNPNPTL--WFSQNSKSFEMnseFSSSMTPSILPPSVTS 294
SANT_TRF cd11660
Telomere repeat binding factor-like DNA-binding domains of the SANT/myb-like family; Human ...
 170-211 7.83e-04

Telomere repeat binding factor-like DNA-binding domains of the SANT/myb-like family; Human telomere repeat binding factors, TRF1 and TRF2, function as part of the 6 component shelterin complex. TRF2 binds DNA and recruits RAP1 (via binding to the RAP1 protein c-terminal (RCT)) and TIN2 in the protection of telomeres from DNA repair machinery. Metazoan shelterin consists of 3 DNA binding proteins (TRF2, TRF1, and POT1) and 3 recruited proteins that bind to one or more of these DNA-binding proteins (RAP1, TIN2, TPP1). Schizosaccharomyces pombe TAZ1 is an orthlog and binds RAP1. Human TRF1 and TRF2 bind double-stranded DNA. hTRF2 consists of a basic N-terminus, a TRF homology domain, the RAP1 binding motif (RBM), the TIN2 binding motif (TBM) and a myb-like DNA binding domain, SANT, named after 'SWI3, ADA2, N-CoR and TFIIIB', several factors that share this domain. Tandem copies of the domain bind telomeric DNA tandem repeats as part of the capping complex. The single myb-like domain of TRF-type proteins is similar to the tandem myb_like domains found in yeast RAP1.


Pssm-ID: 212558 [Multi-domain]  Cd Length: 50  Bit Score: 37.93  E-value: 7.83e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 767168213 170 REWTLEEDLNLISKVKAYGT-KWRKISSEMEFRPSLT---CRNRWR 211
Cdd:cd11660    1 RKWTDEEDEALVEGVEKYGVgNWAKILKDYFFVNNRTsvdLKDKWR 46
SANT_TRF cd11660
Telomere repeat binding factor-like DNA-binding domains of the SANT/myb-like family; Human ...
 118-157 1.12e-03

Telomere repeat binding factor-like DNA-binding domains of the SANT/myb-like family; Human telomere repeat binding factors, TRF1 and TRF2, function as part of the 6 component shelterin complex. TRF2 binds DNA and recruits RAP1 (via binding to the RAP1 protein c-terminal (RCT)) and TIN2 in the protection of telomeres from DNA repair machinery. Metazoan shelterin consists of 3 DNA binding proteins (TRF2, TRF1, and POT1) and 3 recruited proteins that bind to one or more of these DNA-binding proteins (RAP1, TIN2, TPP1). Schizosaccharomyces pombe TAZ1 is an orthlog and binds RAP1. Human TRF1 and TRF2 bind double-stranded DNA. hTRF2 consists of a basic N-terminus, a TRF homology domain, the RAP1 binding motif (RBM), the TIN2 binding motif (TBM) and a myb-like DNA binding domain, SANT, named after 'SWI3, ADA2, N-CoR and TFIIIB', several factors that share this domain. Tandem copies of the domain bind telomeric DNA tandem repeats as part of the capping complex. The single myb-like domain of TRF-type proteins is similar to the tandem myb_like domains found in yeast RAP1.


Pssm-ID: 212558 [Multi-domain]  Cd Length: 50  Bit Score: 37.55  E-value: 1.12e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....
gi 767168213 118 KWTQEEDEQLLKAYEEHGP-HWLSISMD---IPGRTEDQCAKRY 157
Cdd:cd11660    2 KWTDEEDEALVEGVEKYGVgNWAKILKDyffVNNRTSVDLKDKW 45
PLN03091 PLN03091
hypothetical protein; Provisional
 97-152 1.15e-03

hypothetical protein; Provisional


Pssm-ID: 215570 [Multi-domain]  Cd Length: 459  Bit Score: 42.27  E-value: 1.15e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 767168213  97 RTSKDVRKRWTGSLDPNLKKGKWTQEEDEQLLKAYEEHGPHWLSISMDIPGRTEDQ 152
Cdd:PLN03091  48 RCGKSCRLRWINYLRPDLKRGTFSQQEENLIIELHAVLGNRWSQIAAQLPGRTDNE 103
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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