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Conserved domains on  [gi|806951325|ref|WP_046198607|]
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MULTISPECIES: peptidylprolyl isomerase PrsA [Bacillus]

Protein Classification

peptidylprolyl isomerase PrsA( domain architecture ID 11479869)

peptidylprolyl isomerase PrsA plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins, and it functions as a peptidyl-prolyl cis-trans isomerase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides

EC:  5.2.1.8
Gene Ontology:  GO:0003755|GO:0006457
PubMed:  10228556

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
prsA PRK03002
peptidylprolyl isomerase PrsA;
1-285 0e+00

peptidylprolyl isomerase PrsA;


:

Pssm-ID: 101162 [Multi-domain]  Cd Length: 285  Bit Score: 504.08  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806951325   1 MRGKHIFIITALLSILMLSACGQKNDSDTVATATDSTITKSDFEKQLKDRYGKDMLYEMMAQDVITKKYKVSDDDVDKEL 80
Cdd:PRK03002   1 MRGKHIFIITALISILMLSACGQKNSSATVATATDSTITKSDFEKQLKDRYGKDMLYEMMAQDVITKKYKVSDDDVDKEV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806951325  81 QKAKNQYGDQFKNVLKNNGLKDEADFKNQIKFKLAMNEAIKKSITEKDVKDHYKPEIKASHILVSDENEAKEIKKKLDAG 160
Cdd:PRK03002  81 QKAKSQYGDQFKNVLKNNGLKDEADFKNQIKFKLAMNEAIKKSVTEKDVKDHYKPEIKASHILVSDENEAKEIKKKLDAG 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806951325 161 ASFEELAKQESQDLLSKEKGGDLGYFNSGRMAPEFETAAYKLKVGQISNPVTSPNGYHIIKLTDKKELKPYDEVKDSIRK 240
Cdd:PRK03002 161 ASFEELAKQESQDLLSKEKGGDLGYFNSGRMAPEFETAAYKLKVGQISNPVKSPNGYHIIKLTDKKDLKPYDEVKDSIRK 240

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*
gi 806951325 241 NLEEERISDPIFGKKLLQNELKKANIKINDSELEDTFTIVSPQGN 285
Cdd:PRK03002 241 NLEEERTADPIFGKKLLQSELKKANIKINDSELEDTFTIVSPQGN 285
 
Name Accession Description Interval E-value
prsA PRK03002
peptidylprolyl isomerase PrsA;
1-285 0e+00

peptidylprolyl isomerase PrsA;


Pssm-ID: 101162 [Multi-domain]  Cd Length: 285  Bit Score: 504.08  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806951325   1 MRGKHIFIITALLSILMLSACGQKNDSDTVATATDSTITKSDFEKQLKDRYGKDMLYEMMAQDVITKKYKVSDDDVDKEL 80
Cdd:PRK03002   1 MRGKHIFIITALISILMLSACGQKNSSATVATATDSTITKSDFEKQLKDRYGKDMLYEMMAQDVITKKYKVSDDDVDKEV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806951325  81 QKAKNQYGDQFKNVLKNNGLKDEADFKNQIKFKLAMNEAIKKSITEKDVKDHYKPEIKASHILVSDENEAKEIKKKLDAG 160
Cdd:PRK03002  81 QKAKSQYGDQFKNVLKNNGLKDEADFKNQIKFKLAMNEAIKKSVTEKDVKDHYKPEIKASHILVSDENEAKEIKKKLDAG 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806951325 161 ASFEELAKQESQDLLSKEKGGDLGYFNSGRMAPEFETAAYKLKVGQISNPVTSPNGYHIIKLTDKKELKPYDEVKDSIRK 240
Cdd:PRK03002 161 ASFEELAKQESQDLLSKEKGGDLGYFNSGRMAPEFETAAYKLKVGQISNPVKSPNGYHIIKLTDKKDLKPYDEVKDSIRK 240

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*
gi 806951325 241 NLEEERISDPIFGKKLLQNELKKANIKINDSELEDTFTIVSPQGN 285
Cdd:PRK03002 241 NLEEERTADPIFGKKLLQSELKKANIKINDSELEDTFTIVSPQGN 285
SurA COG0760
Peptidyl-prolyl isomerase, parvulin family [Posttranslational modification, protein turnover, ...
 134-266 3.48e-45

Peptidyl-prolyl isomerase, parvulin family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440523 [Multi-domain]  Cd Length: 143  Bit Score: 149.34  E-value: 3.48e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806951325 134 KPEIKASHILVS---------DENEAKEIKKKLDAGASFEELAKQESQDLLSKEKGGDLGYFNSGRMAPEFETAAYKLKV 204
Cdd:COG0760    6 PEEVRASHILVKvppsedrakAEAKAEELLAQLKAGADFAELAKEYSQDPGSAANGGDLGWFSRGQLVPEFEEAAFALKP 85

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 806951325 205 GQISNPVTSPNGYHIIKLTDKKE--LKPYDEVKDSIRKNLEEERIsdpifgKKLLQNELKKANI 266
Cdd:COG0760   86 GEISGPVKTQFGYHIIKVEDRRPaeTPPFEEVKQQIRQELFQQAL------EAWLEELRKKAKI 143
Rotamase pfam00639
PPIC-type PPIASE domain; Rotamases increase the rate of protein folding by catalysing the ...
 147-224 5.88e-27

PPIC-type PPIASE domain; Rotamases increase the rate of protein folding by catalysing the interconversion of cis-proline and trans-proline.


Pssm-ID: 425792 [Multi-domain]  Cd Length: 96  Bit Score: 100.84  E-value: 5.88e-27
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 806951325  147 ENEAKEIKKKLDAGA-SFEELAKQESQDLLSKEKGGDLGYFNSGRMAPEFETAAYKLKVGQISNPVTSPNGYHIIKLTD 224
Cdd:pfam00639  18 KAKAEEILEQLKSGEdSFAELARKYSDDCPSAANGGDLGWFTRGQLPPEFEKAAFALKPGEISGPVETRFGFHIIKLTD 96
 
Name Accession Description Interval E-value
prsA PRK03002
peptidylprolyl isomerase PrsA;
1-285 0e+00

peptidylprolyl isomerase PrsA;


Pssm-ID: 101162 [Multi-domain]  Cd Length: 285  Bit Score: 504.08  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806951325   1 MRGKHIFIITALLSILMLSACGQKNDSDTVATATDSTITKSDFEKQLKDRYGKDMLYEMMAQDVITKKYKVSDDDVDKEL 80
Cdd:PRK03002   1 MRGKHIFIITALISILMLSACGQKNSSATVATATDSTITKSDFEKQLKDRYGKDMLYEMMAQDVITKKYKVSDDDVDKEV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806951325  81 QKAKNQYGDQFKNVLKNNGLKDEADFKNQIKFKLAMNEAIKKSITEKDVKDHYKPEIKASHILVSDENEAKEIKKKLDAG 160
Cdd:PRK03002  81 QKAKSQYGDQFKNVLKNNGLKDEADFKNQIKFKLAMNEAIKKSVTEKDVKDHYKPEIKASHILVSDENEAKEIKKKLDAG 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806951325 161 ASFEELAKQESQDLLSKEKGGDLGYFNSGRMAPEFETAAYKLKVGQISNPVTSPNGYHIIKLTDKKELKPYDEVKDSIRK 240
Cdd:PRK03002 161 ASFEELAKQESQDLLSKEKGGDLGYFNSGRMAPEFETAAYKLKVGQISNPVKSPNGYHIIKLTDKKDLKPYDEVKDSIRK 240

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*
gi 806951325 241 NLEEERISDPIFGKKLLQNELKKANIKINDSELEDTFTIVSPQGN 285
Cdd:PRK03002 241 NLEEERTADPIFGKKLLQSELKKANIKINDSELEDTFTIVSPQGN 285
prsA PRK02998
peptidylprolyl isomerase; Reviewed
 1-277 7.98e-89

peptidylprolyl isomerase; Reviewed


Pssm-ID: 179522 [Multi-domain]  Cd Length: 283  Bit Score: 265.68  E-value: 7.98e-89
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806951325   1 MRGKHIFIITALLSI-LMLSACGQkndSDTVATATDSTITKSDFEKQLKDRYGKDMLYEMMAQDVITKKYKVSDDDVDKE 79
Cdd:PRK02998   1 MKKKKLFLGTIISCVvLALSACGS---SDNVVTSKVGNITEKELSKELRQKYGESTLYQMVLSKALLDKYKVSDEEAKKQ 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806951325  80 LQKAKNQYGDQFKNVLKNNGLKDEADFKNQIKFKLAMNEAIKKSITEKDVKDHYKPEIKASHILVSDENEAKEIKKKLDA 159
Cdd:PRK02998  78 VEEAKDKMGDNFKSTLEQVGLKNEDELKEKMKPEIAFEKAIKATVTEKDVKDNYKPEMKVSHILVKDEKTAKEVKEKVNN 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806951325 160 GASFEELAKQESQDLLSKEKGGDLGYFNSGRMAPEFETAAYKLKVGQISNPVTSPNGYHIIKLTDKKELKPYDEVKDSIR 239
Cdd:PRK02998 158 GEDFAALAKQYSEDTGSKEQGGEISGFAPGQTVKEFEEAAYKLDAGQVSEPVKTTYGYHIIKVTDKKELKPFDEVKDSIR 237

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 806951325 240 KNLEEERISDPI--FGKKLLQNELKKANIKINDSELEDTF 277
Cdd:PRK02998 238 KDLEQQRLQDTTgkWKQQVVNDLLKDADIKVNDKEFKDTF 277
prsA PRK03095
peptidylprolyl isomerase PrsA;
4-277 6.22e-75

peptidylprolyl isomerase PrsA;


Pssm-ID: 179537 [Multi-domain]  Cd Length: 287  Bit Score: 230.65  E-value: 6.22e-75
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806951325   4 KHIFIITALLSILMLSACGQKNdSDTVATATDSTITKSDFEKQLKDRYGKDMLYEMMAQDVITKKYKVSDDDVDKELQKA 83
Cdd:PRK03095   2 KKAMLALAATSVIALSACGTSS-SDKIVTSKAGDITKDEFYEQMKTQAGKQVLNNMVMEKVLIKNYKVEDKEVDKKYDEM 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806951325  84 KNQYGDQFKNVLKNNGLKDEAdFKNQIKFKLAMNEAIKKSITEKDVKDHYKPEIKASHILVSDENEAKEIKKKLDAGASF 163
Cdd:PRK03095  81 KKQYGDQFDTLLKQQGIKEET-LKTGVRAQLAQEKAIEKTITDKELKDNYKPEIKASHILVKDEATAKKVKEELGQGKSF 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806951325 164 EELAKQESQDLLSKEKGGDLGYFNSGRMAPEFETAAYKLKVGQISNPVTSPNGYHIIKLTDKKEL-KPYDEVKDSIRKNL 242
Cdd:PRK03095 160 EELAKQYSEDTGSKEKGGDLGFFGAGKMVKEFEDAAYKLKKDEVSEPVKSQFGYHIIKVTDIKEPeKSFEQSKADIKKEL 239

                        250       260       270
                 ....*....|....*....|....*....|....*
gi 806951325 243 EEERISDPIFGKKLLQNELKKANIKINDSELEDTF 277
Cdd:PRK03095 240 VQKKAQDGEFMNDLMMKEIKKADVKVDDKDLKDLF 274
prsA PRK04405
peptidylprolyl isomerase; Provisional
 4-275 3.48e-46

peptidylprolyl isomerase; Provisional


Pssm-ID: 235295 [Multi-domain]  Cd Length: 298  Bit Score: 156.87  E-value: 3.48e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806951325   4 KHIFIITALLSILM-LSACGqkNDSDTVATATDSTITKSDFEKQLKD-RYGKDMLYEMMAQDVITKKY--KVSDDDVDKE 79
Cdd:PRK04405   6 KKWALAAASAGLALsLAGCS--SNQATVATYSGGKITQSQYYKEMKQsSAGKTVLANMIIYRALEKQYgkKVSTKKVDKQ 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806951325  80 LQKAKNQYGDQFKNVLKNNGLKdEADFKNQIKFKLAMNEAIK--KSITEKDVKDH---YKPEIKASHILVSDENEAKEIK 154
Cdd:PRK04405  84 YNSYKKQYGSSFDSVLSQNGMT-TSSFKQNLRTNLLSEAALKklKKVTNSQLKKAwksYQPKVTVQHILVSKKSTAETVI 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806951325 155 KKLDAGASFEELAKQESQDLLSKEKGGDLGYFNS--GRMAPEFETAAYKLKVGQI-SNPVTSPNGYHIIKLTDKKELKPY 231
Cdd:PRK04405 163 KKLKDGKDFAKLAKKYSTDTATKNKGGKLSAFDStdTTLDSTFKTAAFKLKNGEYtTTPVKTTYGYEVIKMIKHPAKGTF 242

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 806951325 232 DEVKDSIRKNLEEERISDPIFGKKLLQNELKKANIKINDSELED 275
Cdd:PRK04405 243 SDHKKALTKQIYAKWASDSSVMQRVISKVLKKANVSIKDKDLKD 286
SurA COG0760
Peptidyl-prolyl isomerase, parvulin family [Posttranslational modification, protein turnover, ...
 134-266 3.48e-45

Peptidyl-prolyl isomerase, parvulin family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440523 [Multi-domain]  Cd Length: 143  Bit Score: 149.34  E-value: 3.48e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806951325 134 KPEIKASHILVS---------DENEAKEIKKKLDAGASFEELAKQESQDLLSKEKGGDLGYFNSGRMAPEFETAAYKLKV 204
Cdd:COG0760    6 PEEVRASHILVKvppsedrakAEAKAEELLAQLKAGADFAELAKEYSQDPGSAANGGDLGWFSRGQLVPEFEEAAFALKP 85

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 806951325 205 GQISNPVTSPNGYHIIKLTDKKE--LKPYDEVKDSIRKNLEEERIsdpifgKKLLQNELKKANI 266
Cdd:COG0760   86 GEISGPVKTQFGYHIIKVEDRRPaeTPPFEEVKQQIRQELFQQAL------EAWLEELRKKAKI 143
prsA PRK00059
peptidylprolyl isomerase; Provisional
 7-273 1.54e-39

peptidylprolyl isomerase; Provisional


Pssm-ID: 234605 [Multi-domain]  Cd Length: 336  Bit Score: 140.62  E-value: 1.54e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806951325   7 FIITALLSILMLSACGQKN--------DSDTVATATDSTITKSDFEK---------QLKDRYGKD--------------- 54
Cdd:PRK00059   7 LVASLLVGVFIFSAVGCNMiektpeaiAKSTVATVNGEKITRGDLDKdpkmqqvleQLKQQYGDNyekneqvkeqikqqk 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806951325  55 --MLYEMMAQDVITKKYK-----VSDDDVDKELQKAKNQY-------GDQFKNVLKNNGLKDE---ADFKNQIKFKLAMN 117
Cdd:PRK00059  87 eqILDSLITEKVLLQKAKelkliPSEEELNKEVDKKINEIkkqfnndEEQFEEALKATGFTEEtfkEYLKNQIIIEKVIN 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806951325 118 EAIKK-SITEKDVKDHY----------KPEIKASHILVSDENEAKEIKKKLDAGASFEELAKQESQDLLSKEKGGDLGY- 185
Cdd:PRK00059 167 EVVKDvKVTDKDAQKYYnenkskftekPNTMHLAHILVKTEDEAKKVKKRLDKGEDFAKVAKEVSQDPGSKDKGGDLGDv 246

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806951325 186 -FNSGRMAPEFETAAYKLKVGQISNPVTSPNGYHIIKLTDKKE--LKPYDEVKDSIRKNLEEERISDpIFGKKLLQNElK 262
Cdd:PRK00059 247 pYSDSGYDKEFMDGAKALKEGEISAPVKTQFGYHIIKAIKKKEypVKPFDSVKEDIKKQLLQEKQSE-VFKKKIEEWK-K 324

                        330
                 ....*....|.
gi 806951325 263 KANIKINDSEL 273
Cdd:PRK00059 325 ALKVKKYEKNL 335
prsA PRK01326
foldase protein PrsA; Reviewed
 1-278 4.49e-36

foldase protein PrsA; Reviewed


Pssm-ID: 179281 [Multi-domain]  Cd Length: 310  Bit Score: 131.09  E-value: 4.49e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806951325   1 MRGKHIFIITALLSILMLSACGQKNDSDTVATATDSTITKSDFEKQLK-DRYGKDMLYEMMAQDVITKKY--KVSDDDVD 77
Cdd:PRK01326   1 MKKKLIAGAVTLLSVATLAACSKTNENTKVISMKGDTITVSDFYNQVKnNPSAQQAMLNLTISRVFEKQYgdKVSDKEVE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806951325  78 KELQKAKNQYGDQFKNVLKNNGLKDEAdFKNQIK----FKLAMNEAIKKSITEKDVK---DHYKPEIKASHILVSDENEA 150
Cdd:PRK01326  81 KAYAKTAKQYGASFSRALAQAGLTPET-YKAQIRtsklVEYAVKEAAKKELTDEAYKkayEEYTPEVTAQIIRLDNEDKA 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806951325 151 KEIKKKLDA-GASFEELAKQESQdllSKEKGGDLGYFNSGRMAPE-FETAAYKLKVGQISNPVTSP------NGYHIIKL 222
Cdd:PRK01326 160 KSVLEEAKAeGADFAQIAKENTT---TKEKKGEYKFDSGSTNVPEqVKKAAFALDEDGVSDVISVLdptayqSKYYIVKV 236

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 806951325 223 TDKKELKP-YDEVKDSIRKNLEEERISDPIFGKKLLQNELKKANIKINDSELEDTFT 278
Cdd:PRK01326 237 TKKTEKKSdWKDYKKRLKAIILAQKQNDSNFQNKVIAKALDKANVKIKDKAFANILA 293
Rotamase pfam00639
PPIC-type PPIASE domain; Rotamases increase the rate of protein folding by catalysing the ...
 147-224 5.88e-27

PPIC-type PPIASE domain; Rotamases increase the rate of protein folding by catalysing the interconversion of cis-proline and trans-proline.


Pssm-ID: 425792 [Multi-domain]  Cd Length: 96  Bit Score: 100.84  E-value: 5.88e-27
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 806951325  147 ENEAKEIKKKLDAGA-SFEELAKQESQDLLSKEKGGDLGYFNSGRMAPEFETAAYKLKVGQISNPVTSPNGYHIIKLTD 224
Cdd:pfam00639  18 KAKAEEILEQLKSGEdSFAELARKYSDDCPSAANGGDLGWFTRGQLPPEFEKAAFALKPGEISGPVETRFGFHIIKLTD 96
Rotamase_3 pfam13616
PPIC-type PPIASE domain; Rotamases increase the rate of protein folding by catalysing the ...
 119-226 7.45e-27

PPIC-type PPIASE domain; Rotamases increase the rate of protein folding by catalysing the interconversion of cis-proline and trans-proline.


Pssm-ID: 404499 [Multi-domain]  Cd Length: 116  Bit Score: 101.29  E-value: 7.45e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806951325  119 AIKKSITEKDVKDhykpEIKASHILVS-------DENEAK----EIKKKLDAGASFEELAKQESQDLLSKEKGGDLGYFN 187
Cdd:pfam13616   2 SLSKLVDKKSAPD----SVKASHILISysqavsrTEEEAKakadSLLAALKNGADFAALAKTYSDDPASKNNGGDLGWFT 77

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 806951325  188 SGRMAPEFETAAYKLKVGQISNPVTSPNGYHIIKLTDKK 226
Cdd:pfam13616  78 KGQMVKEFEDAVFSLKVGEISGVVKTQFGFHIIKVTDKK 116
PRK12450 PRK12450
foldase protein PrsA; Reviewed
 9-270 1.63e-25

foldase protein PrsA; Reviewed


Pssm-ID: 138982 [Multi-domain]  Cd Length: 309  Bit Score: 102.86  E-value: 1.63e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806951325   9 ITALLSILMLSACGQKNDSDTVATATDSTITKSDFEKQLKD-RYGKDMLYEMMAQDVITKKY--KVSDDDVDKELQKAKN 85
Cdd:PRK12450  11 VVTLATVVTLSACQSSHNNTKLVSMKGDTITVSDFYNETKNtELAQKAMLSLVISRVFETQYanKVSDKEVEKAYKQTAD 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806951325  86 QYGDQFKNVLKNNGLKDEAdFKNQIKFKLAMNEAIK-----KSITEKDVK---DHYKPEIKASHILVSDENEAKEIKKKL 157
Cdd:PRK12450  91 QYGTSFKTVLAQSGLTPET-YKKQIRLTKLVEYAVKeqaknETISKKDYRqayDAYTPTMTAEIMQFEKEEDAKAALEAV 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806951325 158 DA-GASFEELAKQESQdllSKEKGGDLGyFNSG--RMAPEFETAAYKLKVGQIS------NPVTSPNGYHIIKLTDKKEL 228
Cdd:PRK12450 170 KAeGADFAAIAKEKTI---AADKKTTYT-FDSGetTLPAEVVRAASGLKEGNRSeiitalDPATSKRTYHIIKVTKKATK 245

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|...
gi 806951325 229 KP-YDEVKDSIRKNLEEERISDPIFGKKLLQNELKKANIKIND 270
Cdd:PRK12450 246 KAdWKAYQKRLKDIIVTGKLKDPDFQNKVIAKALDKANVKIKD 288
PRK10788 PRK10788
periplasmic folding chaperone; Provisional
 67-271 2.70e-21

periplasmic folding chaperone; Provisional


Pssm-ID: 182731 [Multi-domain]  Cd Length: 623  Bit Score: 93.54  E-value: 2.70e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806951325  67 KKYKVSDDDVdkelqkakNQYGDQFKNvlknnglkdeaDFKNQIKFKL------AMNEAIKKSITEKDVKDHYK------ 134
Cdd:PRK10788 205 AKQTVTDEEI--------KSYYDQNKN-----------NFMAPEQFKVsyikldAATMQQKITVSDADIQAYYDqhqdqf 265

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806951325 135 --PE-IKASHILVSDENEAKEIKKKLDAGASFEELAKQESQDLLSKEKGGDLGYFNSGRMAPEFETAAYKLKvGQISNPV 211
Cdd:PRK10788 266 tqPErKRYSIIQTKTEAEAKAVLDELKKGADFATLAKEKSTDIISARNGGDLGWLEPATTPDELKNAGLKEK-GQLSGVI 344

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 806951325 212 TSPNGYHIIKLTDKK--ELKPYDEVKDSIRKNLEEERISDPIFGkklLQNELKKANIKINDS 271
Cdd:PRK10788 345 KSSVGFLIVRLDDIQpaKVKPLSEVRDDIAAKVKQEKALDAYYA---LQQKVSDAASNDNES 403
PTZ00356 PTZ00356
peptidyl-prolyl cis-trans isomerase (PPIase); Provisional
 137-221 8.07e-18

peptidyl-prolyl cis-trans isomerase (PPIase); Provisional


Pssm-ID: 185573 [Multi-domain]  Cd Length: 115  Bit Score: 77.37  E-value: 8.07e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806951325 137 IKASHILV-------------------SDENEAKEIKKKL----DAGASFEELAKQESqDLLSKEKGGDLGYFNSGRMAP 193
Cdd:PTZ00356   6 VRAAHLLIkhtgsrnpvsrrtgkpvtrSKEEAIKELAKWReqivSGEKTFEEIARQRS-DCGSAAKGGDLGFFGRGQMQK 84

                         90       100
                 ....*....|....*....|....*...
gi 806951325 194 EFETAAYKLKVGQISNPVTSPNGYHIIK 221
Cdd:PTZ00356  85 PFEDAAFALKVGEISDIVHTDSGVHIIL 112
Rotamase_2 pfam13145
PPIC-type PPIASE domain;
124-236 3.25e-15

PPIC-type PPIASE domain;


Pssm-ID: 432992 [Multi-domain]  Cd Length: 121  Bit Score: 70.55  E-value: 3.25e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806951325  124 ITEKDVKDHY--------KPEIKASHILVSDENEAKEIKKKLDAGASFEELAKQESQDLlskEKGGDLGYF-NSGRMAPE 194
Cdd:pfam13145   1 VTEEELKAYYeenkdefsTPEGRLLEILVFKDQVAADAALALLKAGALEDFAALAKGEG---IKAATLDIVeSAELLPEE 77

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 806951325  195 FETAAYKLKVGQISNPVTSPNGYHIIKLTDKKE--LKPYDEVKD 236
Cdd:pfam13145  78 LAKAAFALKPGEVSGPIKTGNGYYVVRVTEIKPaqPLPFEEAKD 121
PRK15441 PRK15441
peptidyl-prolyl cis-trans isomerase C; Provisional
 139-226 7.59e-14

peptidyl-prolyl cis-trans isomerase C; Provisional


Pssm-ID: 185338 [Multi-domain]  Cd Length: 93  Bit Score: 65.82  E-value: 7.59e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806951325 139 ASHILVSDENEAKEIKKKLDAGASFEELAKQESQdLLSKEKGGDLGYFNSGRMAPEFETAAYKLKVGQISNPVTSPNGYH 218
Cdd:PRK15441   7 ALHILVKEEKLALDLLEQIKNGADFGKLAKKHSI-CPSGKRGGDLGEFRQGQMVPAFDKVVFSCPVLEPTGPLHTQFGYH 85


                 ....*...
gi 806951325 219 IIKLTDKK 226
Cdd:PRK15441  86 IIKVLYRN 93
PRK10770 PRK10770
peptidyl-prolyl cis-trans isomerase SurA; Provisional
 136-235 1.53e-11

peptidyl-prolyl cis-trans isomerase SurA; Provisional


Pssm-ID: 236758 [Multi-domain]  Cd Length: 413  Bit Score: 63.99  E-value: 1.53e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806951325 136 EIKASHILVS-------DENEAK--EIKKKLDAG-ASFEELAKQESQDLLSKEKGGDLGYFNSGRMAPEFETAAYKLKVG 205
Cdd:PRK10770 266 EVHARHILLKpspimtdEQARAKleQIAADIKSGkTTFAAAAKEFSQDPGSANQGGDLGWATPDIFDPAFRDALMRLNKG 345

                         90       100       110
                 ....*....|....*....|....*....|
gi 806951325 206 QISNPVTSPNGYHIIKLTDKKELKPYDEVK 235
Cdd:PRK10770 346 QISAPVHSSFGWHLIELLDTRQVDKTDAAQ 375
PRK10770 PRK10770
peptidyl-prolyl cis-trans isomerase SurA; Provisional
 46-224 4.08e-06

peptidyl-prolyl cis-trans isomerase SurA; Provisional


Pssm-ID: 236758 [Multi-domain]  Cd Length: 413  Bit Score: 47.43  E-value: 4.08e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806951325  46 QLKDRYGKDMLYEMMAQDVitkKYKVSDDDVDKELQK--AKNQYG-DQFKNVLKNNGLkDEADFKNQIKFKLAM----NE 118
Cdd:PRK10770  51 QILERLIMDNIILQMAQKM---GVKISDEQLDQAIANiaAQNNMTlDQMRSRLAYDGL-NYNTYRNQIRKEMIIsevrNN 126

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806951325 119 AIKKSIT----EKDV-------KDHYKPEIKASHILV------------SDENEAKEIKKKLDAGASFEELAKQESQDLL 175
Cdd:PRK10770 127 EVRRRITilpqEVDSlakqignQNDASTELNLSHILIplpenptqdqvdEAESQARSIVDQARNGADFGKLAIAYSADQQ 206

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 806951325 176 SKeKGGDLGYFNSGRMAPEFETAAYKLKVGQISNPVTSPNGYHIIKLTD 224
Cdd:PRK10770 207 AL-KGGQMGWGRIQELPGLFAQALSTAKKGDIVGPIRSGVGFHILKVND 254
SurA_N_3 pfam13624
SurA N-terminal domain; This domain is found at the N-terminus of the chaperone SurA. It is a ...
 2-117 5.44e-04

SurA N-terminal domain; This domain is found at the N-terminus of the chaperone SurA. It is a helical domain of unknown function. The C-terminus of the SurA protein folds back and forms part of this domain also but is not included in the current alignment.


Pssm-ID: 433358 [Multi-domain]  Cd Length: 162  Bit Score: 39.86  E-value: 5.44e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806951325    2 RGKHIFIITALLSILMLSACG------QKNDSDTVATATDSTITKSDFEK-------QLKDRYGKDMLYEM-----MAQD 63
Cdd:pfam13624   7 KHAKSWIAKIILGLIILSFVFwgvgsyFSGGGGAVAKVNGEKISRAEFQRayrrqldQLRQQFGPNLDAELldelgLRQQ 86

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 806951325   64 VI------------TKKYK--VSDDDVDKELQKAKN-QYGDQF-----KNVLKNNGLKdEADFKNQIKFKLAMN 117
Cdd:pfam13624  87 VLdqlidralllqeAKKLGlaVSDEEVRQAIASIPAfQEDGKFdkeryRQLLRANGLT-PAEFEASLRQDLLLQ 159
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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