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Conserved domains on  [gi|84794548|ref|NP_001028465|]
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UDP-N-acetylhexosamine pyrophosphorylase-like protein 1 [Mus musculus]

Protein Classification

UDPGP type 1 family protein( domain architecture ID 10135883)

UDPGP type 1 family protein similar to bacterial UTP-glucose-1-phosphate uridylyltransferase, and eukaryotic UDP-N-acetylhexosamine pyrophosphorylase

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
UDPGlcNAc_PPase cd04193
UDPGlcNAc pyrophosphorylase catalayzes the synthesis of UDPGlcNAc; UDP-N-acetylglucosamine ...
 92-413 0e+00

UDPGlcNAc pyrophosphorylase catalayzes the synthesis of UDPGlcNAc; UDP-N-acetylglucosamine (UDPGlcNAc) pyrophosphorylase (UAP) (also named GlcNAc1P uridyltransferase), catalyzes the reversible conversion of UTP and GlcNAc1 to PPi and UDPGlcNAc. UDP-N-acetylglucosamine (UDPGlcNAc), the activated form of GlcNAc, is a key precursor of N- and O-linked glycosylations. It is essential for the synthesis of chitin (a major component of the fungal cell wall) and of the glycosylphosphatidylinositol (GPI) linker which anchors a variety of cell surface proteins to the plasma membrane. In bacteria, UDPGlcNAc represents an essential precursor for both peptidoglycan and lipopolysaccharide biosynthesis. Human UAP has two isoforms, resulting from alternative splicing of a single gene and differing by the presence or absence of 17 amino acids. UDPGlcNAc pyrophosphorylase shares significant sequence and structure conservation with UDPglucose pyrophosphorylase.


:

Pssm-ID: 133036  Cd Length: 323  Bit Score: 558.76  E-value: 0e+00
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84794548  92 RWEEEGFRQISLNKVAVLLLAGGQGTRLGVTYPKGMYQVGLPSQKTLYQLQAERIRRVQQLADQRQGTHCTVPWYIMTSE 171
Cdd:cd04193   2 EWEEAGLKAIAEGKVAVLLLAGGQGTRLGFDGPKGMFPVGLPSKKSLFQLQAERILKLQELAGEASGKKVPIPWYIMTSE 81

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84794548 172 FTLGPTIKFFKEHDFFHLDPTNVVLFEQRMLPAVTFEGKAILERKDKVAMAPDGNGGLYCALADHQILEDMKQRGVEFVH 251
Cdd:cd04193  82 ATHEETRKFFKENNYFGLDPEQVHFFQQGMLPCVDFDGKILLEEKGKIAMAPNGNGGLYKALQTAGILEDMKKRGIKYIH 161

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84794548 252 VYCVDNILVRLADPVFIGFCVLQGADCGAKVVEKAYPEEPVGVVCQVDGVPQVVEYSEISPEIAGQLGADGGLLYNAGNI 331
Cdd:cd04193 162 VYSVDNILVKVADPVFIGFCISKGADVGAKVVRKRYPTEKVGVVVLVDGKPQVVEYSEISDELAEKRDADGELQYNAGNI 241

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84794548 332 CNHFFTRGFLDVVTREFEPLLRLHVAMKKVPYVDEEGNLVKPLRPNGIKMEKFVFDVFQFAKNFVAFEVCREEEFSPLKN 411
Cdd:cd04193 242 ANHFFSLDFLEKAAEMEEPSLPYHIAKKKIPYVDLEGGLVKPDEPNGIKLELFIFDVFPFAKNFVCLEVDREEEFSPLKN 321


                ..
gi 84794548 412 DD 413
Cdd:cd04193 322 AD 323
 
Name Accession Description Interval E-value
UDPGlcNAc_PPase cd04193
UDPGlcNAc pyrophosphorylase catalayzes the synthesis of UDPGlcNAc; UDP-N-acetylglucosamine ...
 92-413 0e+00

UDPGlcNAc pyrophosphorylase catalayzes the synthesis of UDPGlcNAc; UDP-N-acetylglucosamine (UDPGlcNAc) pyrophosphorylase (UAP) (also named GlcNAc1P uridyltransferase), catalyzes the reversible conversion of UTP and GlcNAc1 to PPi and UDPGlcNAc. UDP-N-acetylglucosamine (UDPGlcNAc), the activated form of GlcNAc, is a key precursor of N- and O-linked glycosylations. It is essential for the synthesis of chitin (a major component of the fungal cell wall) and of the glycosylphosphatidylinositol (GPI) linker which anchors a variety of cell surface proteins to the plasma membrane. In bacteria, UDPGlcNAc represents an essential precursor for both peptidoglycan and lipopolysaccharide biosynthesis. Human UAP has two isoforms, resulting from alternative splicing of a single gene and differing by the presence or absence of 17 amino acids. UDPGlcNAc pyrophosphorylase shares significant sequence and structure conservation with UDPglucose pyrophosphorylase.


Pssm-ID: 133036  Cd Length: 323  Bit Score: 558.76  E-value: 0e+00
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84794548  92 RWEEEGFRQISLNKVAVLLLAGGQGTRLGVTYPKGMYQVGLPSQKTLYQLQAERIRRVQQLADQRQGTHCTVPWYIMTSE 171
Cdd:cd04193   2 EWEEAGLKAIAEGKVAVLLLAGGQGTRLGFDGPKGMFPVGLPSKKSLFQLQAERILKLQELAGEASGKKVPIPWYIMTSE 81

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84794548 172 FTLGPTIKFFKEHDFFHLDPTNVVLFEQRMLPAVTFEGKAILERKDKVAMAPDGNGGLYCALADHQILEDMKQRGVEFVH 251
Cdd:cd04193  82 ATHEETRKFFKENNYFGLDPEQVHFFQQGMLPCVDFDGKILLEEKGKIAMAPNGNGGLYKALQTAGILEDMKKRGIKYIH 161

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84794548 252 VYCVDNILVRLADPVFIGFCVLQGADCGAKVVEKAYPEEPVGVVCQVDGVPQVVEYSEISPEIAGQLGADGGLLYNAGNI 331
Cdd:cd04193 162 VYSVDNILVKVADPVFIGFCISKGADVGAKVVRKRYPTEKVGVVVLVDGKPQVVEYSEISDELAEKRDADGELQYNAGNI 241

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84794548 332 CNHFFTRGFLDVVTREFEPLLRLHVAMKKVPYVDEEGNLVKPLRPNGIKMEKFVFDVFQFAKNFVAFEVCREEEFSPLKN 411
Cdd:cd04193 242 ANHFFSLDFLEKAAEMEEPSLPYHIAKKKIPYVDLEGGLVKPDEPNGIKLELFIFDVFPFAKNFVCLEVDREEEFSPLKN 321


                ..
gi 84794548 412 DD 413
Cdd:cd04193 322 AD 323
PLN02435 PLN02435
probable UDP-N-acetylglucosamine pyrophosphorylase
 68-491 8.68e-125

probable UDP-N-acetylglucosamine pyrophosphorylase


Pssm-ID: 215238  Cd Length: 493  Bit Score: 373.44  E-value: 8.68e-125
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84794548   68 AARLQPLPPERVGSAIRCDQETRLRWEEEGFRQISLNKVAVLLLAGGQGTRLGVTYPKGMYQVGLPSQKTLYQLQAERIR 147
Cdd:PLN02435  79 VPAIEPVPENSVSTVEERTPEDRERWWKMGLKAISEGKLAVVLLSGGQGTRLGSSDPKGCFNIGLPSGKSLFQLQAERIL 158

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84794548  148 RVQQLADQRQ----GTHCTVPWYIMTSEFTLGPTIKFFKEHDFFHLDPTNVVLFEQRMLPAVTFEGKAILERKDKVAMAP 223
Cdd:PLN02435 159 CVQRLAAQASsegpGRPVTIHWYIMTSPFTDEATRKFFESHKYFGLEADQVTFFQQGTLPCVSKDGKFIMETPFKVAKAP 238

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84794548  224 DGNGGLYCALADHQILEDMKQRGVEFVHVYCVDNILVRLADPVFIGFCVLQGADCGAKVVEKAYPEEPVGV-VCQVDGVP 302
Cdd:PLN02435 239 DGNGGVYAALKSSRLLEDMASRGIKYVDCYGVDNALVRVADPTFLGYFIDKGVASAAKVVRKAYPQEKVGVfVRRGKGGP 318

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84794548  303 -QVVEYSEISPEIAGQLGADGGLL-YNAGNICNHFFTRGFLDVVTREFEPLLRLHVAMKKVPYVDeeGNLVkplrpnGIK 380
Cdd:PLN02435 319 lTVVEYSELDQAMASAINQQTGRLrYCWSNVCLHMFTLDFLNQVANGLEKDSIYHLAEKKIPSIH--GYTM------GLK 390

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84794548  381 MEKFVFDVFQFAKNFVAFEVCREEEFSPLKNDDTADRDNPSTCRRALLAQHYRWALQAGArFLdVHGVQLtEQSGMlpng 460
Cdd:PLN02435 391 LEQFIFDAFPYAPSTALFEVLREEEFAPVKNANGSNFDTPESARLLVLRLHTRWVVAAGG-FL-THSVPL-YATGV---- 463

                        410       420       430
                 ....*....|....*....|....*....|.
gi 84794548  461 dppaicEISPLVSYSGEGLEMYLQGRQLQSP 491
Cdd:PLN02435 464 ------EVSPLCSYAGENLEAICRGRTFHAP 488
QRI1 COG4284
UDP-N-acetylglucosamine pyrophosphorylase [Carbohydrate transport and metabolism];
10-420 1.26e-117

UDP-N-acetylglucosamine pyrophosphorylase [Carbohydrate transport and metabolism];


Pssm-ID: 443425  Cd Length: 402  Bit Score: 351.88  E-value: 1.26e-117
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84794548  10 QLQRAGQDHLLRFYADLAPEARAALLAELASLEADALrEHCQRAAAAGALAPGPLPDlaARLQPLPPERVGSAIRCDQEt 89
Cdd:COG4284   4 KLEPHGQEHLLRFWDELSEAQQKMLEAQIEEIDIDVF-QHLYRQLVLAEGATGLIPE--SDIEPAPVTDLPLTDLDEVD- 79

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84794548  90 RLRWEEEGFRQISLNKVAVLLLAGGQGTRLGVTYPKGMYQVGLPSQKTLYQLQAERIRRVQQLADQRqgthctVPWYIMT 169
Cdd:COG4284  80 RDRAEEAGEEALRAGKVAVILLAGGQGTRLGFDGPKGLLPVRPVKGKSLFDLIAEQVLAARRRYGVP------LPLYIMT 153

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84794548 170 SEFTLGPTIKFFKEHDFFHLDPTNVVLFEQRMLPAV-TFEGKAILERKDKVAMAPDGNGGLYCALADHQILEDMKQRGVE 248
Cdd:COG4284 154 SFRTHEDTLAFLEEHDYFGLDGLPVHFFLQGMEPALdADLGPVLLPADPELELCPPGHGGIYTALLASGLLDKLLERGIR 233

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84794548 249 FVHVYCVDNILVRLADPVFIGFCVLQGADCGAKVVEKAYPEEPVGVVCQVDGVPQVVEYSEISPEIAGQlgADGGLLYNA 328
Cdd:COG4284 234 YLFVSNVDNPLGAVPDPAFAGWHAASGAPFTAKVVRRTPPDEKVGHLARVDGRLILREYSQLPDEEAEA--FTGELRHPY 311

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84794548 329 GNICNHFFTRGFLDVVTREFEPLLRLHVAMKKVPYVDEEGnlvKPLRPNGIKMEKFVFDVFQFAKNFVAFEVCREEEFSP 408
Cdd:COG4284 312 GNINNHWFDLDFLKRLLDERGLGLPLHRAEKKVDPLDESG---KPTSPNVIKFETFMFDAIPLFDGAVAIEVDREERFAP 388

                       410
                ....*....|..
gi 84794548 409 LKNddTADRDNP 420
Cdd:COG4284 389 VKN--TNGSDSP 398
UDPGP pfam01704
UTP--glucose-1-phosphate uridylyltransferase; This family consists of UTP--glucose-1-phosphate ...
 69-444 7.43e-72

UTP--glucose-1-phosphate uridylyltransferase; This family consists of UTP--glucose-1-phosphate uridylyltransferases, EC:2.7.7.9. Also known as UDP-glucose pyrophosphorylase (UDPGP) and Glucose-1-phosphate uridylyltransferase. UTP--glucose-1-phosphate uridylyltransferase catalyzes the interconversion of MgUTP + glucose-1-phosphate and UDP-glucose + MgPPi. UDP-glucose is an important intermediate in mammalian carbohydrate interconversion involved in various metabolic roles depending on tissue type. In Dictyostelium (slime mold) mutants in this enzyme abort the development cycle. Also within the family is UDP-N-acetylglucosamine or AGX1 and two hypothetical proteins from Borrelia burgdorferi the lyme disease spirochaete Swiss:O51893 and Swiss:O51036.


Pssm-ID: 460300  Cd Length: 412  Bit Score: 234.33  E-value: 7.43e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84794548    69 ARLQPLPPERVgsairCDQETrLRWEEEGFRQIsLNKVAVLLLAGGQGTRLGVTYPKGMYQVGlpSQKTLYQLQaerirr 148
Cdd:pfam01704  24 DKIKPPPEEEI-----VDYED-LQEPEEEIKEL-LNKLAVLKLNGGLGTSMGCVGPKSLIEVR--DGLTFLDLI------ 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84794548   149 VQQLADQRQGTHCTVPWYIMTSEFTLGPTIKFFKEHDFFHLDptnVVLFEQRMLPAVTFEGKAILERK---DKVAMAPDG 225
Cdd:pfam01704  89 VQQIEHLNKKYNVDVPLVLMNSFNTDEDTKKIIRKYKGHKVD---ILTFNQSRYPRIDKDTLLPVPKSadsDEEEWYPPG 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84794548   226 NGGLYCALADHQILEDMKQRGVEFVHVYCVDNiLVRLADPVFIGFCVLQGADCGAKVVEKAYPEEPVGVVCQVDGVPQVV 305
Cdd:pfam01704 166 HGDLYESLYNSGLLDKLLAEGKEYLFVSNIDN-LGATVDLNILNYMVDNGAEFLMEVTDKTRADVKGGTLIEYDGKLRLL 244

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84794548   306 EYSEISPE-IAGQLGADGGLLYNAGNIcnhFFTRGFL-DVVTrefEPLLRLHVAMKKvPYVDEEGNLVKPLRPNGIKMEK 383
Cdd:pfam01704 245 EIAQVPKEhVDEFKSIKKFKIFNTNNI---WINLKALkRVVE---EGELQLEIIVNK-KTLDNGENVIQLETAVGAAIKN 317

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 84794548   384 FvfdvfqfaKNFVAFEVCReEEFSPLKnddtadrdnpsTCRRALLAQHYRWALQAGARFLD 444
Cdd:pfam01704 318 F--------KNAIGINVPR-SRFLPVK-----------TTSDLLLVMSDLYVLNHGSLIMN 358
 
Name Accession Description Interval E-value
UDPGlcNAc_PPase cd04193
UDPGlcNAc pyrophosphorylase catalayzes the synthesis of UDPGlcNAc; UDP-N-acetylglucosamine ...
 92-413 0e+00

UDPGlcNAc pyrophosphorylase catalayzes the synthesis of UDPGlcNAc; UDP-N-acetylglucosamine (UDPGlcNAc) pyrophosphorylase (UAP) (also named GlcNAc1P uridyltransferase), catalyzes the reversible conversion of UTP and GlcNAc1 to PPi and UDPGlcNAc. UDP-N-acetylglucosamine (UDPGlcNAc), the activated form of GlcNAc, is a key precursor of N- and O-linked glycosylations. It is essential for the synthesis of chitin (a major component of the fungal cell wall) and of the glycosylphosphatidylinositol (GPI) linker which anchors a variety of cell surface proteins to the plasma membrane. In bacteria, UDPGlcNAc represents an essential precursor for both peptidoglycan and lipopolysaccharide biosynthesis. Human UAP has two isoforms, resulting from alternative splicing of a single gene and differing by the presence or absence of 17 amino acids. UDPGlcNAc pyrophosphorylase shares significant sequence and structure conservation with UDPglucose pyrophosphorylase.


Pssm-ID: 133036  Cd Length: 323  Bit Score: 558.76  E-value: 0e+00
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84794548  92 RWEEEGFRQISLNKVAVLLLAGGQGTRLGVTYPKGMYQVGLPSQKTLYQLQAERIRRVQQLADQRQGTHCTVPWYIMTSE 171
Cdd:cd04193   2 EWEEAGLKAIAEGKVAVLLLAGGQGTRLGFDGPKGMFPVGLPSKKSLFQLQAERILKLQELAGEASGKKVPIPWYIMTSE 81

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84794548 172 FTLGPTIKFFKEHDFFHLDPTNVVLFEQRMLPAVTFEGKAILERKDKVAMAPDGNGGLYCALADHQILEDMKQRGVEFVH 251
Cdd:cd04193  82 ATHEETRKFFKENNYFGLDPEQVHFFQQGMLPCVDFDGKILLEEKGKIAMAPNGNGGLYKALQTAGILEDMKKRGIKYIH 161

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84794548 252 VYCVDNILVRLADPVFIGFCVLQGADCGAKVVEKAYPEEPVGVVCQVDGVPQVVEYSEISPEIAGQLGADGGLLYNAGNI 331
Cdd:cd04193 162 VYSVDNILVKVADPVFIGFCISKGADVGAKVVRKRYPTEKVGVVVLVDGKPQVVEYSEISDELAEKRDADGELQYNAGNI 241

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84794548 332 CNHFFTRGFLDVVTREFEPLLRLHVAMKKVPYVDEEGNLVKPLRPNGIKMEKFVFDVFQFAKNFVAFEVCREEEFSPLKN 411
Cdd:cd04193 242 ANHFFSLDFLEKAAEMEEPSLPYHIAKKKIPYVDLEGGLVKPDEPNGIKLELFIFDVFPFAKNFVCLEVDREEEFSPLKN 321


                ..
gi 84794548 412 DD 413
Cdd:cd04193 322 AD 323
PLN02435 PLN02435
probable UDP-N-acetylglucosamine pyrophosphorylase
 68-491 8.68e-125

probable UDP-N-acetylglucosamine pyrophosphorylase


Pssm-ID: 215238  Cd Length: 493  Bit Score: 373.44  E-value: 8.68e-125
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84794548   68 AARLQPLPPERVGSAIRCDQETRLRWEEEGFRQISLNKVAVLLLAGGQGTRLGVTYPKGMYQVGLPSQKTLYQLQAERIR 147
Cdd:PLN02435  79 VPAIEPVPENSVSTVEERTPEDRERWWKMGLKAISEGKLAVVLLSGGQGTRLGSSDPKGCFNIGLPSGKSLFQLQAERIL 158

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84794548  148 RVQQLADQRQ----GTHCTVPWYIMTSEFTLGPTIKFFKEHDFFHLDPTNVVLFEQRMLPAVTFEGKAILERKDKVAMAP 223
Cdd:PLN02435 159 CVQRLAAQASsegpGRPVTIHWYIMTSPFTDEATRKFFESHKYFGLEADQVTFFQQGTLPCVSKDGKFIMETPFKVAKAP 238

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84794548  224 DGNGGLYCALADHQILEDMKQRGVEFVHVYCVDNILVRLADPVFIGFCVLQGADCGAKVVEKAYPEEPVGV-VCQVDGVP 302
Cdd:PLN02435 239 DGNGGVYAALKSSRLLEDMASRGIKYVDCYGVDNALVRVADPTFLGYFIDKGVASAAKVVRKAYPQEKVGVfVRRGKGGP 318

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84794548  303 -QVVEYSEISPEIAGQLGADGGLL-YNAGNICNHFFTRGFLDVVTREFEPLLRLHVAMKKVPYVDeeGNLVkplrpnGIK 380
Cdd:PLN02435 319 lTVVEYSELDQAMASAINQQTGRLrYCWSNVCLHMFTLDFLNQVANGLEKDSIYHLAEKKIPSIH--GYTM------GLK 390

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84794548  381 MEKFVFDVFQFAKNFVAFEVCREEEFSPLKNDDTADRDNPSTCRRALLAQHYRWALQAGArFLdVHGVQLtEQSGMlpng 460
Cdd:PLN02435 391 LEQFIFDAFPYAPSTALFEVLREEEFAPVKNANGSNFDTPESARLLVLRLHTRWVVAAGG-FL-THSVPL-YATGV---- 463

                        410       420       430
                 ....*....|....*....|....*....|.
gi 84794548  461 dppaicEISPLVSYSGEGLEMYLQGRQLQSP 491
Cdd:PLN02435 464 ------EVSPLCSYAGENLEAICRGRTFHAP 488
QRI1 COG4284
UDP-N-acetylglucosamine pyrophosphorylase [Carbohydrate transport and metabolism];
10-420 1.26e-117

UDP-N-acetylglucosamine pyrophosphorylase [Carbohydrate transport and metabolism];


Pssm-ID: 443425  Cd Length: 402  Bit Score: 351.88  E-value: 1.26e-117
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84794548  10 QLQRAGQDHLLRFYADLAPEARAALLAELASLEADALrEHCQRAAAAGALAPGPLPDlaARLQPLPPERVGSAIRCDQEt 89
Cdd:COG4284   4 KLEPHGQEHLLRFWDELSEAQQKMLEAQIEEIDIDVF-QHLYRQLVLAEGATGLIPE--SDIEPAPVTDLPLTDLDEVD- 79

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84794548  90 RLRWEEEGFRQISLNKVAVLLLAGGQGTRLGVTYPKGMYQVGLPSQKTLYQLQAERIRRVQQLADQRqgthctVPWYIMT 169
Cdd:COG4284  80 RDRAEEAGEEALRAGKVAVILLAGGQGTRLGFDGPKGLLPVRPVKGKSLFDLIAEQVLAARRRYGVP------LPLYIMT 153

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84794548 170 SEFTLGPTIKFFKEHDFFHLDPTNVVLFEQRMLPAV-TFEGKAILERKDKVAMAPDGNGGLYCALADHQILEDMKQRGVE 248
Cdd:COG4284 154 SFRTHEDTLAFLEEHDYFGLDGLPVHFFLQGMEPALdADLGPVLLPADPELELCPPGHGGIYTALLASGLLDKLLERGIR 233

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84794548 249 FVHVYCVDNILVRLADPVFIGFCVLQGADCGAKVVEKAYPEEPVGVVCQVDGVPQVVEYSEISPEIAGQlgADGGLLYNA 328
Cdd:COG4284 234 YLFVSNVDNPLGAVPDPAFAGWHAASGAPFTAKVVRRTPPDEKVGHLARVDGRLILREYSQLPDEEAEA--FTGELRHPY 311

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84794548 329 GNICNHFFTRGFLDVVTREFEPLLRLHVAMKKVPYVDEEGnlvKPLRPNGIKMEKFVFDVFQFAKNFVAFEVCREEEFSP 408
Cdd:COG4284 312 GNINNHWFDLDFLKRLLDERGLGLPLHRAEKKVDPLDESG---KPTSPNVIKFETFMFDAIPLFDGAVAIEVDREERFAP 388

                       410
                ....*....|..
gi 84794548 409 LKNddTADRDNP 420
Cdd:COG4284 389 VKN--TNGSDSP 398
PTZ00339 PTZ00339
UDP-N-acetylglucosamine pyrophosphorylase; Provisional
 94-494 1.99e-109

UDP-N-acetylglucosamine pyrophosphorylase; Provisional


Pssm-ID: 240368  Cd Length: 482  Bit Score: 333.63  E-value: 1.99e-109
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84794548   94 EEEGFRQISLNKVAVLLLAGGQGTRLGVTYPKGMYQVGLPSQKTLYQLQAERIRRVQQLADQRQGTH--CTVPWYIMTSE 171
Cdd:PTZ00339  95 KESGLEIIKKGEVAVLILAGGLGTRLGSDKPKGLLECTPVKKKTLFQFHCEKVRRLEEMAVAVSGGGddPTIYILVLTSS 174

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84794548  172 FTLGPTIKFFKEHDFFHLDPTNVVLFEQRMLPAVT-FEGKAILERKDKVAMAPDGNGGLYCALADHQILEDMKQRGVEFV 250
Cdd:PTZ00339 175 FNHDQTRQFLEENNFFGLDKEQVIFFKQSSLPCYDeNTGRFIMSSQGSLCTAPGGNGDVFKALAKCSELMDIVRKGIKYV 254

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84794548  251 HVYCVDNILVRLADPVFIGFCVLQGADCGAKVVEKAYPEEPVGVVCQVDGVPQVVEYSEISPEI-AGQLGADGGLLYNAG 329
Cdd:PTZ00339 255 QVISIDNILAKVLDPEFIGLASSFPAHDVLNKCVKREDDESVGVFCLKDYEWQVVEYTEINERIlNNDELLTGELAFNYG 334

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84794548  330 NICNHFFTRGFL-DVVTREFEPLLRLHVAMKKVPYVDEEGNLvkplrPNGIKMEKFVFDVFQFAKNFVAFEVCREEEFSP 408
Cdd:PTZ00339 335 NICSHIFSLDFLkKVAANRLYESTPYHAARKKIPYINGPTDK-----TMGIKLEAFIFDIFRYAKNVLILEVDREDEFAP 409

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84794548  409 LKNDDTADRDNPSTCRRALLAQHYRWALQAGArfldvhGVQLTEQSGMLpngdppaICEISPLVSYSGEGLEMYLQGRQL 488
Cdd:PTZ00339 410 IKNADGAAADTILNAQKLLLSLHTRWLEAALE------TVAGNPREGLN-------LCEISPLVSYGGEGLFQYPGKKIL 476


                 ....*.
gi 84794548  489 QSPFIL 494
Cdd:PTZ00339 477 GLPEIL 482
UGPase_euk_like cd04180
Eukaryotic UGPase-like includes UDPase and UDPGlcNAc pyrophosphorylase enzymes; This family ...
 106-411 7.36e-84

Eukaryotic UGPase-like includes UDPase and UDPGlcNAc pyrophosphorylase enzymes; This family includes UDP-Glucose Pyrophosphorylase (UDPase) and UDPGlcNAc pyrophosphorylase enzymes. The two enzymes share significant sequence and structure similarity. UDP-Glucose Pyrophosphorylase catalyzes a reversible production of UDP-Glucose and pyrophosphate (PPi) from Glucose-1-phosphate and UTP. UDP-glucose plays pivotal roles in galactose utilization, in glycogen synthesis, and in the synthesis of the carbohydrate moieties of glycolipids , glycoproteins , and proteoglycans . UDP-N-acetylglucosamine (UDPGlcNAc) pyrophosphorylase (UAP) (also named GlcNAc1P uridyltransferase), catalyzes the reversible conversion of UTP and GlcNAc1P from PPi and UDPGlcNAc, which is a key precursor of N- and O-linked glycosylations and is essential for the synthesis of chitin (a major component of the fungal cell wall) and of the glycosylphosphatidylinositol (GPI) linker anchoring a variety of cell surface proteins to the plasma membrane. In bacteria, UDPGlcNAc represents an essential precursor for both peptidoglycan and lipopolysaccharide biosynthesis.


Pssm-ID: 133023  Cd Length: 266  Bit Score: 260.57  E-value: 7.36e-84
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84794548 106 VAVLLLAGGQGTRLGVTYPKGMYQVGLPSQKTLYQLQAERIRRVQQLADQRqgthCTVPWYIMTSEFTLGPTIKFFKEHD 185
Cdd:cd04180   1 VAVVLLAGGLGTRLGKDGPKSSTDVGLPSGQCFLQLIGEKILTLQEIDLYS----CKIPEQLMNSKYTHEKTQCYFEKIN 76

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84794548 186 ffhLDPTNVVLFEQRMLPAVTFEGKAILERKDKVAMAPDGNGGLYCALADHQILEDMKQRGVEFVHVYCVDNILVRLADP 265
Cdd:cd04180  77 ---QKNSYVITFMQGKLPLKNDDDARDPHNKTKCHLFPCGHGDVVLALIHSGHLNKLLEKGYRYIHFIGVDNLLVKVADP 153

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84794548 266 VFIGFCVLQGADCGAKVVEKAYPEEPVGVVCQVD-GVPQVVEYSEISPEIA------GQLGADGGLLYNAGNICNHFFTR 338
Cdd:cd04180 154 LFIGIAIQNRKAINQKVVPKTRNEESGGYRIANInGRVQLLEYDQIKKLLKqkmvnnQIPKDIDDAPFFLFNTNNLINFL 233

                       250       260       270       280       290       300       310
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 84794548 339 GFLdvvtrefepllrlhvamkkvpyvdeegnlvkplrpngikmEKFVFDVFQFAKNFVAFEVCREEEFSPLKN 411
Cdd:cd04180 234 VEF----------------------------------------KDRVDDIIEFTDDIVGVMVHRAEEFAPVKN 266
UDPGP pfam01704
UTP--glucose-1-phosphate uridylyltransferase; This family consists of UTP--glucose-1-phosphate ...
 69-444 7.43e-72

UTP--glucose-1-phosphate uridylyltransferase; This family consists of UTP--glucose-1-phosphate uridylyltransferases, EC:2.7.7.9. Also known as UDP-glucose pyrophosphorylase (UDPGP) and Glucose-1-phosphate uridylyltransferase. UTP--glucose-1-phosphate uridylyltransferase catalyzes the interconversion of MgUTP + glucose-1-phosphate and UDP-glucose + MgPPi. UDP-glucose is an important intermediate in mammalian carbohydrate interconversion involved in various metabolic roles depending on tissue type. In Dictyostelium (slime mold) mutants in this enzyme abort the development cycle. Also within the family is UDP-N-acetylglucosamine or AGX1 and two hypothetical proteins from Borrelia burgdorferi the lyme disease spirochaete Swiss:O51893 and Swiss:O51036.


Pssm-ID: 460300  Cd Length: 412  Bit Score: 234.33  E-value: 7.43e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84794548    69 ARLQPLPPERVgsairCDQETrLRWEEEGFRQIsLNKVAVLLLAGGQGTRLGVTYPKGMYQVGlpSQKTLYQLQaerirr 148
Cdd:pfam01704  24 DKIKPPPEEEI-----VDYED-LQEPEEEIKEL-LNKLAVLKLNGGLGTSMGCVGPKSLIEVR--DGLTFLDLI------ 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84794548   149 VQQLADQRQGTHCTVPWYIMTSEFTLGPTIKFFKEHDFFHLDptnVVLFEQRMLPAVTFEGKAILERK---DKVAMAPDG 225
Cdd:pfam01704  89 VQQIEHLNKKYNVDVPLVLMNSFNTDEDTKKIIRKYKGHKVD---ILTFNQSRYPRIDKDTLLPVPKSadsDEEEWYPPG 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84794548   226 NGGLYCALADHQILEDMKQRGVEFVHVYCVDNiLVRLADPVFIGFCVLQGADCGAKVVEKAYPEEPVGVVCQVDGVPQVV 305
Cdd:pfam01704 166 HGDLYESLYNSGLLDKLLAEGKEYLFVSNIDN-LGATVDLNILNYMVDNGAEFLMEVTDKTRADVKGGTLIEYDGKLRLL 244

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84794548   306 EYSEISPE-IAGQLGADGGLLYNAGNIcnhFFTRGFL-DVVTrefEPLLRLHVAMKKvPYVDEEGNLVKPLRPNGIKMEK 383
Cdd:pfam01704 245 EIAQVPKEhVDEFKSIKKFKIFNTNNI---WINLKALkRVVE---EGELQLEIIVNK-KTLDNGENVIQLETAVGAAIKN 317

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 84794548   384 FvfdvfqfaKNFVAFEVCReEEFSPLKnddtadrdnpsTCRRALLAQHYRWALQAGARFLD 444
Cdd:pfam01704 318 F--------KNAIGINVPR-SRFLPVK-----------TTSDLLLVMSDLYVLNHGSLIMN 358
UGGPase cd06424
UGGPase catalyzes the synthesis of UDP-Glucose/UDP-Galactose; UGGPase: UDP-Galactose/Glucose ...
 106-312 5.32e-15

UGGPase catalyzes the synthesis of UDP-Glucose/UDP-Galactose; UGGPase: UDP-Galactose/Glucose Pyrophosphorylase catalyzes the reversible production of UDP-Glucose/UDP-Galactose and pyrophosphate (PPi) from Glucose-1-phosphate/Galactose-1-phosphate and UTP. Its dual substrate specificity distinguishes it from the single substrate enzyme UDP-glucose pyrophosphorylase. It may play a key role in the galactose metabolism in raffinose oligosaccharide (RFO) metabolizing plants. RFO raffinose is a major photoassimilate and is a galactosylderivative of sucrose (Suc) containing a galactose (Gal) moiety. Upon arriving at the sink tissue, the Gal moieties of the RFOs are initially removed by alpha-galactosidase and then are phosphorylated to Gal-1-P. Gal-1-P is converted to UDP-Gal. The UDP-Gal is further metabolized to UDP-Glc via an epimerase reaction. The UDP-Glc can be directly utilized in cell wall metabolism or in Suc synthesis. However, for the Suc synthesis UDP-Glc must be further metabolized to Glc-1-P. This can be carried out either by the UGPase in the reverse direction or by the dual substrate PPase itself operating in the reverse direction. According to the latter possibility, the three-step pathway of Gal-1-P to Glc-1-P could be carried out by a single PPase, functioning sequentially in reverse directions separated by the epimerase reaction.


Pssm-ID: 133046  Cd Length: 315  Bit Score: 75.96  E-value: 5.32e-15
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84794548 106 VAVLLLAGGQGTRLGVTYPKGMYQVGLPSQKTLYQLQAERIRRVQQLAdqRQGTHCTVPWYIMTSEFTLGPTIKFFKEHD 185
Cdd:cd06424   1 AVFVLVAGGLGERLGYSGIKIGLPVELTTNTTYLQYYLNYIRAFQEAS--KKGEKMEIPFVIMTSDDTHSKTLKLLEENN 78

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84794548 186 FFHLDPTNVVLFEQRMLPAVTFEGKAI---LERKDKVAMAPDGNGGLYCALADHQILEDMKQRGVEFVHVYCVDNILVRL 262
Cdd:cd06424  79 YFGLEKDQVHILKQEKVFCLIDNDAHLaldPDNTYSILTKPHGHGDVHTLLYNSGLLKKWIEAGYKWLVFFQDTNALAFK 158

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|....*
gi 84794548 263 ADPVFIGFCVLQGADCGAKVVEKAyPEEPVGVVCQ---VDGVPQV--VEYSEISP 312
Cdd:cd06424 159 AIPAVLGVSATKSLDMNSLTVPRK-PKEAIGALCKltkNNGKSMTinVEYNQLDP 212
PLN02830 PLN02830
UDP-sugar pyrophosphorylase
 94-312 1.52e-13

UDP-sugar pyrophosphorylase


Pssm-ID: 215444  Cd Length: 615  Bit Score: 73.18  E-value: 1.52e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84794548   94 EEEGFRQIslNKVAVLLLAGGQGTRLGVTYPKgmyqVGLPSQKT----LYQLQAERIRRVQQLADQRQG-THCTVPWYIM 168
Cdd:PLN02830 119 EEAGLREA--GNAAFVLVAGGLGERLGYSGIK----VALPTETAtgtcYLQLYIESILALQERAKKRKAkKGRKIPLVIM 192

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84794548  169 TSEFTLGPTIKFFKEHDFFHLDPTNVVLFEQRMLPAVTfEGKA--ILERKD--KVAMAPDGNGGLYCALADHQILEDMKQ 244
Cdd:PLN02830 193 TSDDTHARTLKLLERNDYFGMDPDQVTLLKQEKVACLM-DNDArlALDPNDpyKIQTKPHGHGDVHALLYSSGLLDKWLS 271

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 84794548  245 RGVEFVHVYCVDNILVRLADPVFIGFCVLQGADCGAKVV-EKAypEEPVGVVCQ---VDGVPQV--VEYSEISP 312
Cdd:PLN02830 272 AGKKWVVFFQDTNGLVFKAIPAALGVSATKGFDMNSLAVpRKA--KEAIGAIAKlthKDGREMVinVEYNQLDP 343
UGPase_euk cd00897
Eukaryotic UGPase catalyses the synthesis of UDP-Glucose; UGPase (UDP-Glucose ...
 103-257 4.45e-09

Eukaryotic UGPase catalyses the synthesis of UDP-Glucose; UGPase (UDP-Glucose Pyrophosphorylase) catalyzes the reversible production of UDP-Glucose and pyrophosphate (PPi) from Glucose-1-phosphate and UTP. UDP-glucose plays pivotal roles in galactose utilization, in glycogen synthesis, and in the synthesis of the carbohydrate moieties of glycolipids, glycoproteins, and proteoglycans. UGPase is found in both prokaryotes and eukaryotes. Interestingly, while the prokaryotic and eukaryotic forms of UGPase catalyze the same reaction, they share low sequence similarity. This family consists of mainly eukaryotic UTP-glucose-1-phosphate uridylyltransferases.


Pssm-ID: 132998  Cd Length: 300  Bit Score: 57.64  E-value: 4.45e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84794548 103 LNKVAVLLLAGGQGTRLGVTYPKGMYQVglPSQKTLYQLQaerirrVQQLADQRQGTHCTVPWYIMTSEFTLGPTIKFFK 182
Cdd:cd00897   1 LNKLVVLKLNGGLGTSMGCTGPKSLIEV--RDGKTFLDLT------VQQIEHLNKTYGVDVPLVLMNSFNTDEDTKKILK 72

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 84794548 183 EHDFFHLDptnVVLFEQRMLPAV---TFEGKAILERKDKVAMAPDGNGGLYCALADHQILEDMKQRGVEFVHVYCVDN 257
Cdd:cd00897  73 KYAGVNVD---IHTFNQSRYPRIskeTLLPVPSWADSPDEEWYPPGHGDIFESLYNSGLLDTLLAQGKEYLFVSNIDN 147
PLN02474 PLN02474
UTP--glucose-1-phosphate uridylyltransferase
 103-258 1.61e-06

UTP--glucose-1-phosphate uridylyltransferase


Pssm-ID: 178092  Cd Length: 469  Bit Score: 50.64  E-value: 1.61e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84794548  103 LNKVAVLLLAGGQGTRLGVTYPKGMYQV--GLpsqkTLYQLQaerirrVQQLADQRQGTHCTVPWYIMTSEFTLGPTIKF 180
Cdd:PLN02474  77 LDKLVVLKLNGGLGTTMGCTGPKSVIEVrnGL----TFLDLI------VIQIENLNKKYGCNVPLLLMNSFNTHDDTQKI 146

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84794548  181 FKEHDFFHLDptnVVLFEQRMLPAVTFEGKAILERK---DKVAMAPDGNGGLYCALADHQILEDMKQRGVEFVHVYCVDN 257
Cdd:PLN02474 147 VEKYTNSNIE---IHTFNQSQYPRVVADDFVPWPSKgktDKDGWYPPGHGDVFPSLMNSGKLDALLSQGKEYVFIANSDN 223


                 .
gi 84794548  258 I 258
Cdd:PLN02474 224 L 224
MobA COG0746
Molybdopterin-guanine dinucleotide biosynthesis protein A [Coenzyme transport and metabolism]; ...
 104-149 6.10e-03

Molybdopterin-guanine dinucleotide biosynthesis protein A [Coenzyme transport and metabolism]; Molybdopterin-guanine dinucleotide biosynthesis protein A is part of the Pathway/BioSystem: Molybdopterin biosynthesis


Pssm-ID: 440509 [Multi-domain]  Cd Length: 188  Bit Score: 37.86  E-value: 6.10e-03
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*.
gi 84794548 104 NKVAVLLLAGGQGTRLGVtyPKGMYQVGlpsQKTLYQLQAERIRRV 149
Cdd:COG0746   3 MPITGVILAGGRSRRMGQ--DKALLPLG---GRPLLERVLERLRPQ 43
CDP-ME_synthetase cd02516
CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; ...
 106-131 9.61e-03

CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; 4-diphosphocytidyl-2-methyl-D-erythritol synthase (CDP-ME), also called 2C-methyl-d-erythritol 4-phosphate cytidylyltransferase catalyzes the third step in the alternative (non-mevalonate) pathway of Isopentenyl diphosphate (IPP) biosynthesis: the formation of 4-diphosphocytidyl-2C-methyl-D-erythritol from CTP and 2C-methyl-D-erythritol 4-phosphate. This mevalonate independent pathway that utilizes pyruvate and glyceraldehydes 3-phosphate as starting materials for production of IPP occurs in a variety of bacteria, archaea and plant cells, but is absent in mammals. Thus, CDP-ME synthetase is an attractive targets for the structure-based design of selective antibacterial, herbicidal and antimalarial drugs.


Pssm-ID: 133009 [Multi-domain]  Cd Length: 218  Bit Score: 37.50  E-value: 9.61e-03
                        10        20
                ....*....|....*....|....*.
gi 84794548 106 VAVLLLAGGQGTRLGVTYPKGMYQVG 131
Cdd:cd02516   1 VAAIILAAGSGSRMGADIPKQFLELG 26
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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