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Conserved domains on  [gi|887923|gb|AAC52308|]
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KRAB-zinc finger protein 79, partial [Mus musculus]

Protein Classification

C2H2-type zinc finger protein( domain architecture ID 10603440)

Cys2His2 (C2H2)-type zinc finger protein may be involved in transcriptional regulation

CATH:  3.30.160.60
Gene Ontology:  GO:0008270|GO:0003677
PubMed:  11361095|22803940|30718982

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SFP1 super family cl25788
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 7-92 1.15e-05

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


The actual alignment was detected with superfamily member COG5189:

Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 43.17  E-value: 1.15e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887923     7 ENEQEKKMQIVLQGHATRVTPKSQQ--SGEKAFWCKYDGCGKLYTTAHHLKVH---------------ERSHTG----DR 65
Cdd:COG5189 318 CTNSSSNGKLAHGGERNIDTPSRMLkvKDGKPYKCPVEGCNKKYKNQNGLKYHmlhghqnqklhenpsPEKMNIfsakDK 397

                        90       100
                ....*....|....*....|....*..
gi 887923    66 PYQCEHsgCGKAFATGYGLKSHfRTHT 92
Cdd:COG5189 398 PYRCEV--CDKRYKNLNGLKYH-RKHS 421
zf-H2C2_2 pfam13465
Zinc-finger double domain;
84-110 8.66e-04

Zinc-finger double domain;


:

Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 34.65  E-value: 8.66e-04
                          10        20
                  ....*....|....*....|....*..
gi 887923      84 LKSHFRTHTGEKPYRCSEdnCTKSFKT 110
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPE--CGKSFKS 26
 
Name Accession Description Interval E-value
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 7-92 1.15e-05

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 43.17  E-value: 1.15e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887923     7 ENEQEKKMQIVLQGHATRVTPKSQQ--SGEKAFWCKYDGCGKLYTTAHHLKVH---------------ERSHTG----DR 65
Cdd:COG5189 318 CTNSSSNGKLAHGGERNIDTPSRMLkvKDGKPYKCPVEGCNKKYKNQNGLKYHmlhghqnqklhenpsPEKMNIfsakDK 397

                        90       100
                ....*....|....*....|....*..
gi 887923    66 PYQCEHsgCGKAFATGYGLKSHfRTHT 92
Cdd:COG5189 398 PYRCEV--CDKRYKNLNGLKYH-RKHS 421
zf-H2C2_2 pfam13465
Zinc-finger double domain;
84-110 8.66e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 34.65  E-value: 8.66e-04
                          10        20
                  ....*....|....*....|....*..
gi 887923      84 LKSHFRTHTGEKPYRCSEdnCTKSFKT 110
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPE--CGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
53-80 3.49e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 33.11  E-value: 3.49e-03
                          10        20
                  ....*....|....*....|....*...
gi 887923      53 HLKVHERSHTGDRPYQCEHsgCGKAFAT 80
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPE--CGKSFKS 26
 
Name Accession Description Interval E-value
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 7-92 1.15e-05

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 43.17  E-value: 1.15e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887923     7 ENEQEKKMQIVLQGHATRVTPKSQQ--SGEKAFWCKYDGCGKLYTTAHHLKVH---------------ERSHTG----DR 65
Cdd:COG5189 318 CTNSSSNGKLAHGGERNIDTPSRMLkvKDGKPYKCPVEGCNKKYKNQNGLKYHmlhghqnqklhenpsPEKMNIfsakDK 397

                        90       100
                ....*....|....*....|....*..
gi 887923    66 PYQCEHsgCGKAFATGYGLKSHfRTHT 92
Cdd:COG5189 398 PYRCEV--CDKRYKNLNGLKYH-RKHS 421
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
44-130 8.28e-05

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 40.83  E-value: 8.28e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887923    44 CGKLYTTAHHLKVHERS--HTG--DRPYQCEHSGCGKAFATGYGLKSHFRTHTGEKPYRCSEDNCTKSF---KTSGDQQK 116
Cdd:COG5048 295 CNISFSRSSPLTRHLRSvnHSGesLKPFSCPYSLCGKLFSRNDALKRHILLHTSISPAKEKLLNSSSKFsplLNNEPPQS 374

                        90
                ....*....|....
gi 887923   117 AHQNPYRRKGPLSV 130
Cdd:COG5048 375 LQQYKDLKNDKKSE 388
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
40-114 1.54e-04

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 40.06  E-value: 1.54e-04
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 887923    40 KYDGCGKLYTTAHHLKVHERSHTGDRPYQCEHSGCGKAFATGYGLKSHFRTHTGEKPYRCSEDNCTKSFKTSGDQ 114
Cdd:COG5048  35 SCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPLSNSKASSSS 109
zf-H2C2_2 pfam13465
Zinc-finger double domain;
84-110 8.66e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 34.65  E-value: 8.66e-04
                          10        20
                  ....*....|....*....|....*..
gi 887923      84 LKSHFRTHTGEKPYRCSEdnCTKSFKT 110
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPE--CGKSFKS 26
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 63-109 1.29e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 37.39  E-value: 1.29e-03
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 887923    63 GDRPYQCEHSGCGKAFATGYGLKSHfRTH--------------------TGEKPYRCseDNCTKSFK 109
Cdd:COG5189 346 DGKPYKCPVEGCNKKYKNQNGLKYH-MLHghqnqklhenpspekmnifsAKDKPYRC--EVCDKRYK 409
zf-H2C2_2 pfam13465
Zinc-finger double domain;
53-80 3.49e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 33.11  E-value: 3.49e-03
                          10        20
                  ....*....|....*....|....*...
gi 887923      53 HLKVHERSHTGDRPYQCEHsgCGKAFAT 80
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPE--CGKSFKS 26
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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