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Conserved domains on  [gi|922549590|ref|XP_013602781|]
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PREDICTED: EPIDERMAL PATTERNING FACTOR-like protein 9 [Brassica oleracea var. oleracea]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
stomagen-like super family cl25585
stomagen domain family; Stomagen, also called EPIDERMAL PATTERNING FACTOR-like protein 9 ...
 1-101 3.74e-37

stomagen domain family; Stomagen, also called EPIDERMAL PATTERNING FACTOR-like protein 9 (EPFL9 or STOMAGEN), or EPF-like protein 9, is plant peptide hormone expressed in the mesophyll, that acts as a positive regulator of stomatal density and patterning. It competes with EPIDERMAL PATTERNING FACTORS 2 (EPF2) for binding to the ERECTA receptor, while it also competes with EPF1 and EPF2 for binding to TOO MANY MOUTHS (TMM), both receptors for the EPF peptides to initiate a signal cascade for stomatal development. EPFL9 cannot be cleaved by the protease CO2 RESPONSE SECRETED PROTEASE (CRSP). Stomagen is composed of a loop and a scaffold containing three disulphide bonds. It belongs to the fold-family of small globular knottins.


The actual alignment was detected with superfamily member PLN03207:

Pssm-ID: 452405  Cd Length: 113  Bit Score: 121.12  E-value: 3.74e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922549590   1 MKHEMSNMKLRCISFFFLLFGLLLGNFIVEASKARSI-----------DDTLSLPRQVHLP-YSRRHMIGSTAPTCTYNE 68
Cdd:PLN03207   1 MANECMTATTRCLTLFFLLFFLLLGAYVIQGSRNQSIlpydqsisyphQETVKLLNGGHLSkSSRRLMIGSTAPTCTYNE 80

                         90       100       110
                 ....*....|....*....|....*....|...
gi 922549590  69 CRGCRYKCRAEQVPVEGNDPINSAYHYRCVCHR 101
Cdd:PLN03207  81 CRGCRYKCRAEQVPVEGNDPINSAYHYKCVCHR 113
 
Name Accession Description Interval E-value
PLN03207 PLN03207
stomagen; Provisional
 1-101 3.74e-37

stomagen; Provisional


Pssm-ID: 215632  Cd Length: 113  Bit Score: 121.12  E-value: 3.74e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922549590   1 MKHEMSNMKLRCISFFFLLFGLLLGNFIVEASKARSI-----------DDTLSLPRQVHLP-YSRRHMIGSTAPTCTYNE 68
Cdd:PLN03207   1 MANECMTATTRCLTLFFLLFFLLLGAYVIQGSRNQSIlpydqsisyphQETVKLLNGGHLSkSSRRLMIGSTAPTCTYNE 80

                         90       100       110
                 ....*....|....*....|....*....|...
gi 922549590  69 CRGCRYKCRAEQVPVEGNDPINSAYHYRCVCHR 101
Cdd:PLN03207  81 CRGCRYKCRAEQVPVEGNDPINSAYHYKCVCHR 113
Stomagen pfam16851
Stomagen; Stomagen (epidermal patterning factor-like protein 9) acts as a positive regulator ...
 52-100 1.84e-26

Stomagen; Stomagen (epidermal patterning factor-like protein 9) acts as a positive regulator of stomatal development.


Pssm-ID: 407095  Cd Length: 50  Bit Score: 92.21  E-value: 1.84e-26
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 922549590   52 SRRHMIGSTAPTCTYNECRGCRYKCRAEQVPVEGNDPINSAYHYRCVCH 100
Cdd:pfam16851   2 ARRLMIGSTAPTCTYNECRGCRTKCRAEQVPVDANDPMNSAYHYRCVCH 50
stomagen-like cd22743
stomagen domain family; Stomagen, also called EPIDERMAL PATTERNING FACTOR-like protein 9 ...
 57-101 4.34e-16

stomagen domain family; Stomagen, also called EPIDERMAL PATTERNING FACTOR-like protein 9 (EPFL9 or STOMAGEN), or EPF-like protein 9, is plant peptide hormone expressed in the mesophyll, that acts as a positive regulator of stomatal density and patterning. It competes with EPIDERMAL PATTERNING FACTORS 2 (EPF2) for binding to the ERECTA receptor, while it also competes with EPF1 and EPF2 for binding to TOO MANY MOUTHS (TMM), both receptors for the EPF peptides to initiate a signal cascade for stomatal development. EPFL9 cannot be cleaved by the protease CO2 RESPONSE SECRETED PROTEASE (CRSP). Stomagen is composed of a loop and a scaffold containing three disulphide bonds. It belongs to the fold-family of small globular knottins.


Pssm-ID: 439359  Cd Length: 45  Bit Score: 65.94  E-value: 4.34e-16
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 922549590  57 IGSTAPTCTYNECRGCRYKCRAEQVPVEGNDPINSAYHYRCVCHR 101
Cdd:cd22743    1 IGSTAPTCTYNECRGCRYKCRAEQVPVEGNDPINSAYHYRCVCHR 45
 
Name Accession Description Interval E-value
PLN03207 PLN03207
stomagen; Provisional
 1-101 3.74e-37

stomagen; Provisional


Pssm-ID: 215632  Cd Length: 113  Bit Score: 121.12  E-value: 3.74e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922549590   1 MKHEMSNMKLRCISFFFLLFGLLLGNFIVEASKARSI-----------DDTLSLPRQVHLP-YSRRHMIGSTAPTCTYNE 68
Cdd:PLN03207   1 MANECMTATTRCLTLFFLLFFLLLGAYVIQGSRNQSIlpydqsisyphQETVKLLNGGHLSkSSRRLMIGSTAPTCTYNE 80

                         90       100       110
                 ....*....|....*....|....*....|...
gi 922549590  69 CRGCRYKCRAEQVPVEGNDPINSAYHYRCVCHR 101
Cdd:PLN03207  81 CRGCRYKCRAEQVPVEGNDPINSAYHYKCVCHR 113
Stomagen pfam16851
Stomagen; Stomagen (epidermal patterning factor-like protein 9) acts as a positive regulator ...
 52-100 1.84e-26

Stomagen; Stomagen (epidermal patterning factor-like protein 9) acts as a positive regulator of stomatal development.


Pssm-ID: 407095  Cd Length: 50  Bit Score: 92.21  E-value: 1.84e-26
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 922549590   52 SRRHMIGSTAPTCTYNECRGCRYKCRAEQVPVEGNDPINSAYHYRCVCH 100
Cdd:pfam16851   2 ARRLMIGSTAPTCTYNECRGCRTKCRAEQVPVDANDPMNSAYHYRCVCH 50
stomagen-like cd22743
stomagen domain family; Stomagen, also called EPIDERMAL PATTERNING FACTOR-like protein 9 ...
 57-101 4.34e-16

stomagen domain family; Stomagen, also called EPIDERMAL PATTERNING FACTOR-like protein 9 (EPFL9 or STOMAGEN), or EPF-like protein 9, is plant peptide hormone expressed in the mesophyll, that acts as a positive regulator of stomatal density and patterning. It competes with EPIDERMAL PATTERNING FACTORS 2 (EPF2) for binding to the ERECTA receptor, while it also competes with EPF1 and EPF2 for binding to TOO MANY MOUTHS (TMM), both receptors for the EPF peptides to initiate a signal cascade for stomatal development. EPFL9 cannot be cleaved by the protease CO2 RESPONSE SECRETED PROTEASE (CRSP). Stomagen is composed of a loop and a scaffold containing three disulphide bonds. It belongs to the fold-family of small globular knottins.


Pssm-ID: 439359  Cd Length: 45  Bit Score: 65.94  E-value: 4.34e-16
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 922549590  57 IGSTAPTCTYNECRGCRYKCRAEQVPVEGNDPINSAYHYRCVCHR 101
Cdd:cd22743    1 IGSTAPTCTYNECRGCRYKCRAEQVPVEGNDPINSAYHYRCVCHR 45
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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