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Conserved domains on  [gi|939687002|ref|XP_014287577|]
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uncharacterized protein LOC106687921 isoform X2 [Halyomorpha halys]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GPS2_interact pfam15784
G-protein pathway suppressor 2-interacting domain; GPS2_interact is the more N-terminal domain ...
 191-275 1.02e-31

G-protein pathway suppressor 2-interacting domain; GPS2_interact is the more N-terminal domain of two co-repressor protein-families found in vertebrates. The domain is found in NCoR and SMRT proteins; N-CoR (nuclear receptor co-repressor) and SMRT (silencing mediator for retinoid and thyroid receptors) are related corepressors that mediate transcriptional repression by unliganded nuclear receptors and other classes of transcriptional repressors. GPS2 is a stoichiometric subunit of the N-CoR-HDAC3 complex. GPS2 links the complex to membrane receptor-related intracellular JNK (c-Jun amino-terminal kinase) signalling pathways.


:

Pssm-ID: 464868 [Multi-domain]  Cd Length: 89  Bit Score: 119.58  E-value: 1.02e-31
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939687002   191 YNPQVEAISPTLPSEA--LQEDANFRSTKDDLLHGIAKVDREITKTELQISKLKRKQQELEEAAKKPAIKKEEEEVP--Q 266
Cdd:pfam15784    1 YYPQVEAISPTLPSPEgqDQELSPFRSSKDELLQNIDKVDREIAKVEQQISKLKKKQQQLEEEAAKPPEPEEPVSPPpsE 80


                   ....*....
gi 939687002   267 PKHQSPAQK 275
Cdd:pfam15784   81 SKHRSLAQI 89
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 775-815 1.37e-06

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


:

Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 46.73  E-value: 1.37e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 939687002   775 WTDEEIESLKNAIKLHGMNWHEVSQSV-GKPQHHCMNFFFTY 815
Cdd:pfam00249    4 WTPEEDELLLEAVEKLGNRWKKIAKLLpGRTDNQCKNRWQNY 45
SANT super family cl21498
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 469-512 4.08e-06

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


The actual alignment was detected with superfamily member cd11661:

Pssm-ID: 473887 [Multi-domain]  Cd Length: 46  Bit Score: 45.30  E-value: 4.08e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 939687002  469 WTQSEKEMFKEKFMQHPKNFGMI-ASYLDKKSVCDCVQYYYLSKK 512
Cdd:cd11661     2 WSESEAKLFEEGLRKYGKDFHDIrQDFLPWKSVGELVEFYYMWKK 46
PTZ00121 super family cl31754
MAEBL; Provisional
 208-487 2.48e-05

MAEBL; Provisional


The actual alignment was detected with superfamily member PTZ00121:

Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 49.75  E-value: 2.48e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939687002  208 QEDANFRSTKDDLLHGIAKV-DREITKTELQISKLKRKQQELEEAAKKPA--IKKEEEE---VPQPKHQSPAQKIYAENR 281
Cdd:PTZ00121 1573 EEDKNMALRKAEEAKKAEEArIEEVMKLYEEEKKMKAEEAKKAEEAKIKAeeLKKAEEEkkkVEQLKKKEAEEKKKAEEL 1652

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939687002  282 RKAQDAHMLLANlgptihlplynqpSDTTIYHENKKKHIGFRKRLLDHLRK-KHIERELREKRLTTTYSHMVQEWLKKVE 360
Cdd:PTZ00121 1653 KKAEEENKIKAA-------------EEAKKAEEDKKKAEEAKKAEEDEKKAaEALKKEAEEAKKAEELKKKEAEEKKKAE 1719

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939687002  361 ---KIENSQKRKGKDAKNREYFEKifPKLRKQREDRERFNRVGARVKSEADLEE---------IMDGLQEQEME-----D 423
Cdd:PTZ00121 1720 elkKAEEENKIKAEEAKKEAEEDK--KKAEEAKKDEEEKKKIAHLKKEEEKKAEeirkekeavIEEELDEEDEKrrmevD 1797

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 939687002  424 KKMRSYAVVPPLLLDAKQRSIYYVNNNGRLEDFA----ADYKEKQLlnvwtQSEKEMFKEKFMQHPKN 487
Cdd:PTZ00121 1798 KKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAikevADSKNMQL-----EEADAFEKHKFNKNNEN 1860
 
Name Accession Description Interval E-value
GPS2_interact pfam15784
G-protein pathway suppressor 2-interacting domain; GPS2_interact is the more N-terminal domain ...
 191-275 1.02e-31

G-protein pathway suppressor 2-interacting domain; GPS2_interact is the more N-terminal domain of two co-repressor protein-families found in vertebrates. The domain is found in NCoR and SMRT proteins; N-CoR (nuclear receptor co-repressor) and SMRT (silencing mediator for retinoid and thyroid receptors) are related corepressors that mediate transcriptional repression by unliganded nuclear receptors and other classes of transcriptional repressors. GPS2 is a stoichiometric subunit of the N-CoR-HDAC3 complex. GPS2 links the complex to membrane receptor-related intracellular JNK (c-Jun amino-terminal kinase) signalling pathways.


Pssm-ID: 464868 [Multi-domain]  Cd Length: 89  Bit Score: 119.58  E-value: 1.02e-31
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939687002   191 YNPQVEAISPTLPSEA--LQEDANFRSTKDDLLHGIAKVDREITKTELQISKLKRKQQELEEAAKKPAIKKEEEEVP--Q 266
Cdd:pfam15784    1 YYPQVEAISPTLPSPEgqDQELSPFRSSKDELLQNIDKVDREIAKVEQQISKLKKKQQQLEEEAAKPPEPEEPVSPPpsE 80


                   ....*....
gi 939687002   267 PKHQSPAQK 275
Cdd:pfam15784   81 SKHRSLAQI 89
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 775-815 1.37e-06

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 46.73  E-value: 1.37e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 939687002   775 WTDEEIESLKNAIKLHGMNWHEVSQSV-GKPQHHCMNFFFTY 815
Cdd:pfam00249    4 WTPEEDELLLEAVEKLGNRWKKIAKLLpGRTDNQCKNRWQNY 45
SANT_MTA3_like cd11661
Myb-Like Dna-Binding Domain of MTA3 and related proteins; Members in this SANT/myb family ...
 469-512 4.08e-06

Myb-Like Dna-Binding Domain of MTA3 and related proteins; Members in this SANT/myb family include domains found in mouse metastasis-associated protein 3 (MTA3) proteins and arginine-glutamic dipeptide (RERE) repeats proteins. SANT (SWI3, ADA2, N-CoR and TFIIIB) DNA-binding domains are a diverse set of proteins that share a common 3 alpha-helix bundle. MTA3 has been shown to interact with nucleosome remodeling and deacetylase (NuRD) proteins CHD4 and HDAC1, and the core cohesin complex protein RAD21 in the ovary, and regulate G2/M progression in proliferating granulosa cells. RERE belongs to the atrophin family and has been identified as a nuclear receptor corepressor; altered expression levels of RERE are associated with cancer in humans while mutations of Rere in mice cause failure in closing the anterior neural tube and fusion of the telencephalic and optic vesicles during embryogenesis.


Pssm-ID: 212559 [Multi-domain]  Cd Length: 46  Bit Score: 45.30  E-value: 4.08e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 939687002  469 WTQSEKEMFKEKFMQHPKNFGMI-ASYLDKKSVCDCVQYYYLSKK 512
Cdd:cd11661     2 WSESEAKLFEEGLRKYGKDFHDIrQDFLPWKSVGELVEFYYMWKK 46
PTZ00121 PTZ00121
MAEBL; Provisional
 208-487 2.48e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 49.75  E-value: 2.48e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939687002  208 QEDANFRSTKDDLLHGIAKV-DREITKTELQISKLKRKQQELEEAAKKPA--IKKEEEE---VPQPKHQSPAQKIYAENR 281
Cdd:PTZ00121 1573 EEDKNMALRKAEEAKKAEEArIEEVMKLYEEEKKMKAEEAKKAEEAKIKAeeLKKAEEEkkkVEQLKKKEAEEKKKAEEL 1652

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939687002  282 RKAQDAHMLLANlgptihlplynqpSDTTIYHENKKKHIGFRKRLLDHLRK-KHIERELREKRLTTTYSHMVQEWLKKVE 360
Cdd:PTZ00121 1653 KKAEEENKIKAA-------------EEAKKAEEDKKKAEEAKKAEEDEKKAaEALKKEAEEAKKAEELKKKEAEEKKKAE 1719

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939687002  361 ---KIENSQKRKGKDAKNREYFEKifPKLRKQREDRERFNRVGARVKSEADLEE---------IMDGLQEQEME-----D 423
Cdd:PTZ00121 1720 elkKAEEENKIKAEEAKKEAEEDK--KKAEEAKKDEEEKKKIAHLKKEEEKKAEeirkekeavIEEELDEEDEKrrmevD 1797

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 939687002  424 KKMRSYAVVPPLLLDAKQRSIYYVNNNGRLEDFA----ADYKEKQLlnvwtQSEKEMFKEKFMQHPKN 487
Cdd:PTZ00121 1798 KKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAikevADSKNMQL-----EEADAFEKHKFNKNNEN 1860
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
467-513 3.29e-04

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 39.90  E-value: 3.29e-04
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*...
gi 939687002    467 NVWTQSEKEMFKEKFMQHP-KNFGMIASYLDKKSVCDCVQYYYLSKKT 513
Cdd:smart00717    2 GEWTEEEDELLIELVKKYGkNNWEKIAKELPGRTAEQCRERWRNLLKP 49
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 775-815 1.01e-03

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 38.33  E-value: 1.01e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 939687002  775 WTDEEIESLKNAIKLHGM-NWHEVSQSVG-KPQHHCMNFFFTY 815
Cdd:cd00167     2 WTEEEDELLLEAVKKYGKnNWEKIAKELPgRTPKQCRERWRNL 44
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 469-508 1.93e-03

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 37.87  E-value: 1.93e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 939687002   469 WTQSEKEMFKEKFMQHPKNFGMIASYLDKKSVCDCVQYYY 508
Cdd:pfam00249    4 WTPEEDELLLEAVEKLGNRWKKIAKLLPGRTDNQCKNRWQ 43
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
775-803 3.86e-03

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 36.82  E-value: 3.86e-03
                            10        20        30
                    ....*....|....*....|....*....|
gi 939687002    775 WTDEEIESLKNAIKLHGM-NWHEVSQSVGK 803
Cdd:smart00717    4 WTEEEDELLIELVKKYGKnNWEKIAKELPG 33
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 204-422 5.40e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.29  E-value: 5.40e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939687002  204 SEALQEDANFRSTKDDLLHGIAKVDREITKTELQISKLKRKQQELEEAAKKpaIKKEEEEVPQPKHQSpaQKIYAENRRK 283
Cdd:COG4942    37 AELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAE--LEKEIAELRAELEAQ--KEELAELLRA 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939687002  284 AQdahmLLANLGPTIHLPLYNQPSDTTIYHENKKKHIGFRKRLLDHLRKKHIERELREKRLTTTyshmvQEWLKKVEKIE 363
Cdd:COG4942   113 LY----RLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAE-----RAELEALLAEL 183

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 939687002  364 NSQKRKGKDAKNREyfEKIFPKLRKQREDRERfnRVGARVKSEADLEEIMDGLQEQEME 422
Cdd:COG4942   184 EEERAALEALKAER--QKLLARLEKELAELAA--ELAELQQEAEELEALIARLEAEAAA 238
 
Name Accession Description Interval E-value
GPS2_interact pfam15784
G-protein pathway suppressor 2-interacting domain; GPS2_interact is the more N-terminal domain ...
 191-275 1.02e-31

G-protein pathway suppressor 2-interacting domain; GPS2_interact is the more N-terminal domain of two co-repressor protein-families found in vertebrates. The domain is found in NCoR and SMRT proteins; N-CoR (nuclear receptor co-repressor) and SMRT (silencing mediator for retinoid and thyroid receptors) are related corepressors that mediate transcriptional repression by unliganded nuclear receptors and other classes of transcriptional repressors. GPS2 is a stoichiometric subunit of the N-CoR-HDAC3 complex. GPS2 links the complex to membrane receptor-related intracellular JNK (c-Jun amino-terminal kinase) signalling pathways.


Pssm-ID: 464868 [Multi-domain]  Cd Length: 89  Bit Score: 119.58  E-value: 1.02e-31
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939687002   191 YNPQVEAISPTLPSEA--LQEDANFRSTKDDLLHGIAKVDREITKTELQISKLKRKQQELEEAAKKPAIKKEEEEVP--Q 266
Cdd:pfam15784    1 YYPQVEAISPTLPSPEgqDQELSPFRSSKDELLQNIDKVDREIAKVEQQISKLKKKQQQLEEEAAKPPEPEEPVSPPpsE 80


                   ....*....
gi 939687002   267 PKHQSPAQK 275
Cdd:pfam15784   81 SKHRSLAQI 89
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 775-815 1.37e-06

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 46.73  E-value: 1.37e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 939687002   775 WTDEEIESLKNAIKLHGMNWHEVSQSV-GKPQHHCMNFFFTY 815
Cdd:pfam00249    4 WTPEEDELLLEAVEKLGNRWKKIAKLLpGRTDNQCKNRWQNY 45
SANT_MTA3_like cd11661
Myb-Like Dna-Binding Domain of MTA3 and related proteins; Members in this SANT/myb family ...
 469-512 4.08e-06

Myb-Like Dna-Binding Domain of MTA3 and related proteins; Members in this SANT/myb family include domains found in mouse metastasis-associated protein 3 (MTA3) proteins and arginine-glutamic dipeptide (RERE) repeats proteins. SANT (SWI3, ADA2, N-CoR and TFIIIB) DNA-binding domains are a diverse set of proteins that share a common 3 alpha-helix bundle. MTA3 has been shown to interact with nucleosome remodeling and deacetylase (NuRD) proteins CHD4 and HDAC1, and the core cohesin complex protein RAD21 in the ovary, and regulate G2/M progression in proliferating granulosa cells. RERE belongs to the atrophin family and has been identified as a nuclear receptor corepressor; altered expression levels of RERE are associated with cancer in humans while mutations of Rere in mice cause failure in closing the anterior neural tube and fusion of the telencephalic and optic vesicles during embryogenesis.


Pssm-ID: 212559 [Multi-domain]  Cd Length: 46  Bit Score: 45.30  E-value: 4.08e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 939687002  469 WTQSEKEMFKEKFMQHPKNFGMI-ASYLDKKSVCDCVQYYYLSKK 512
Cdd:cd11661     2 WSESEAKLFEEGLRKYGKDFHDIrQDFLPWKSVGELVEFYYMWKK 46
PTZ00121 PTZ00121
MAEBL; Provisional
 208-487 2.48e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 49.75  E-value: 2.48e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939687002  208 QEDANFRSTKDDLLHGIAKV-DREITKTELQISKLKRKQQELEEAAKKPA--IKKEEEE---VPQPKHQSPAQKIYAENR 281
Cdd:PTZ00121 1573 EEDKNMALRKAEEAKKAEEArIEEVMKLYEEEKKMKAEEAKKAEEAKIKAeeLKKAEEEkkkVEQLKKKEAEEKKKAEEL 1652

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939687002  282 RKAQDAHMLLANlgptihlplynqpSDTTIYHENKKKHIGFRKRLLDHLRK-KHIERELREKRLTTTYSHMVQEWLKKVE 360
Cdd:PTZ00121 1653 KKAEEENKIKAA-------------EEAKKAEEDKKKAEEAKKAEEDEKKAaEALKKEAEEAKKAEELKKKEAEEKKKAE 1719

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939687002  361 ---KIENSQKRKGKDAKNREYFEKifPKLRKQREDRERFNRVGARVKSEADLEE---------IMDGLQEQEME-----D 423
Cdd:PTZ00121 1720 elkKAEEENKIKAEEAKKEAEEDK--KKAEEAKKDEEEKKKIAHLKKEEEKKAEeirkekeavIEEELDEEDEKrrmevD 1797

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 939687002  424 KKMRSYAVVPPLLLDAKQRSIYYVNNNGRLEDFA----ADYKEKQLlnvwtQSEKEMFKEKFMQHPKN 487
Cdd:PTZ00121 1798 KKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAikevADSKNMQL-----EEADAFEKHKFNKNNEN 1860
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 469-508 3.11e-04

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 39.87  E-value: 3.11e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 939687002  469 WTQSEKEMFKEKFMQHP-KNFGMIASYLDKKSVCDCVQYYY 508
Cdd:cd00167     2 WTEEEDELLLEAVKKYGkNNWEKIAKELPGRTPKQCRERWR 42
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
467-513 3.29e-04

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 39.90  E-value: 3.29e-04
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*...
gi 939687002    467 NVWTQSEKEMFKEKFMQHP-KNFGMIASYLDKKSVCDCVQYYYLSKKT 513
Cdd:smart00717    2 GEWTEEEDELLIELVKKYGkNNWEKIAKELPGRTAEQCRERWRNLLKP 49
SANT cd00167
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ...
 775-815 1.01e-03

'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.


Pssm-ID: 238096 [Multi-domain]  Cd Length: 45  Bit Score: 38.33  E-value: 1.01e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 939687002  775 WTDEEIESLKNAIKLHGM-NWHEVSQSVG-KPQHHCMNFFFTY 815
Cdd:cd00167     2 WTEEEDELLLEAVKKYGKnNWEKIAKELPgRTPKQCRERWRNL 44
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 469-508 1.93e-03

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 37.87  E-value: 1.93e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 939687002   469 WTQSEKEMFKEKFMQHPKNFGMIASYLDKKSVCDCVQYYY 508
Cdd:pfam00249    4 WTPEEDELLLEAVEKLGNRWKKIAKLLPGRTDNQCKNRWQ 43
SANT smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
775-803 3.86e-03

SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;


Pssm-ID: 197842 [Multi-domain]  Cd Length: 49  Bit Score: 36.82  E-value: 3.86e-03
                            10        20        30
                    ....*....|....*....|....*....|
gi 939687002    775 WTDEEIESLKNAIKLHGM-NWHEVSQSVGK 803
Cdd:smart00717    4 WTEEEDELLIELVKKYGKnNWEKIAKELPG 33
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 204-422 5.40e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.29  E-value: 5.40e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939687002  204 SEALQEDANFRSTKDDLLHGIAKVDREITKTELQISKLKRKQQELEEAAKKpaIKKEEEEVPQPKHQSpaQKIYAENRRK 283
Cdd:COG4942    37 AELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAE--LEKEIAELRAELEAQ--KEELAELLRA 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939687002  284 AQdahmLLANLGPTIHLPLYNQPSDTTIYHENKKKHIGFRKRLLDHLRKKHIERELREKRLTTTyshmvQEWLKKVEKIE 363
Cdd:COG4942   113 LY----RLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAE-----RAELEALLAEL 183

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 939687002  364 NSQKRKGKDAKNREyfEKIFPKLRKQREDRERfnRVGARVKSEADLEEIMDGLQEQEME 422
Cdd:COG4942   184 EEERAALEALKAER--QKLLARLEKELAELAA--ELAELQQEAEELEALIARLEAEAAA 238
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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