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Conserved domains on  [gi|960352056|gb|ALR84792|]
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NADH dehydrogenase subunit 2, partial (mitochondrion) [Taeniopygia guttata]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 super family cl33352
NADH dehydrogenase subunit 2; Provisional
 1-161 6.69e-85

NADH dehydrogenase subunit 2; Provisional


The actual alignment was detected with superfamily member MTH00112:

Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 252.82  E-value: 6.69e-85
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960352056   1 LIFITSLLLGTTITISSNHWITAWAGLEINTLAILPLISKSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWHTGQWDI 80
Cdd:MTH00112   7 LIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWNTGQWDI 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960352056  81 TQLTHPTSCLILTSAIAMKLGLVPFHFWFPEVLQGSPLTTGLILSTAMKLPPMTLLFMTSPSLNPALLTTMAILSTALGG 160
Cdd:MTH00112  87 TQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAILSTLIGG 166


                 .
gi 960352056 161 W 161
Cdd:MTH00112 167 W 167
 
Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-161 6.69e-85

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 252.82  E-value: 6.69e-85
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960352056   1 LIFITSLLLGTTITISSNHWITAWAGLEINTLAILPLISKSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWHTGQWDI 80
Cdd:MTH00112   7 LIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWNTGQWDI 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960352056  81 TQLTHPTSCLILTSAIAMKLGLVPFHFWFPEVLQGSPLTTGLILSTAMKLPPMTLLFMTSPSLNPALLTTMAILSTALGG 160
Cdd:MTH00112  87 TQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAILSTLIGG 166


                 .
gi 960352056 161 W 161
Cdd:MTH00112 167 W 167
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 8-159 4.20e-15

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 71.30  E-value: 4.20e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960352056   8 LLGTTITISSNHWITAWAGLEINTLAILPLIS-KSHHPRAIEAATKYFLTQAAASALVLF-SSMTNAWhTGQWDITQLTH 85
Cdd:COG1007  112 TLGMMLMASANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLGALSSGFLLYgISLLYGA-TGSLNLAGIAA 190

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960352056  86 PTS------------CLILTSAIAMKLGLVPFHFWFPEVLQGSPLTTGLILSTAMKL----PPMTLLFMTSPSLNPA--- 146
Cdd:COG1007  191 ALAagganspllllgLVLVLAGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIaafaALLRLLVEAFPGLAADwql 270

                        170
                 ....*....|...
gi 960352056 147 LLTTMAILSTALG 159
Cdd:COG1007  271 LLAVLAVLSMTVG 283
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 8-130 2.50e-12

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 63.43  E-value: 2.50e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960352056    8 LLGTTITISSNHWITAWAGLEINTLAILPLIS-KSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWHTGQWDITQLTHP 86
Cdd:TIGR01770 112 LLGIFLLVSSNDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLNFEDLLLF 191

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 960352056   87 TSCLILT------------SAIAMKLGLVPFHFWFPEVLQGSPLTTGLILSTAMKL 130
Cdd:TIGR01770 192 LSNGMLNisllllgivlilVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKI 247
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 17-141 8.64e-10

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 55.78  E-value: 8.64e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960352056   17 SNHWITAWAGLEINTLAILPLI-SKSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWHTGQWDITQL-----------T 84
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIgYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELskaltgglnssG 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 960352056   85 HPTSCLILTSAIAMKLGLVPFHFWFPEVLQGSPLTTGLIL-STAMKLPPMTLLFMTSP 141
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLaATLVKAGGYGLIRRSLL 138
 
Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-161 6.69e-85

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 252.82  E-value: 6.69e-85
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960352056   1 LIFITSLLLGTTITISSNHWITAWAGLEINTLAILPLISKSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWHTGQWDI 80
Cdd:MTH00112   7 LIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWNTGQWDI 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960352056  81 TQLTHPTSCLILTSAIAMKLGLVPFHFWFPEVLQGSPLTTGLILSTAMKLPPMTLLFMTSPSLNPALLTTMAILSTALGG 160
Cdd:MTH00112  87 TQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAILSTLIGG 166


                 .
gi 960352056 161 W 161
Cdd:MTH00112 167 W 167
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 2-161 4.86e-74

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 225.19  E-value: 4.86e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960352056   2 IFITSLLLGTTITISSNHWITAWAGLEINTLAILPLISKSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWHTGQWDIT 81
Cdd:MTH00070   8 ILLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTINAWFTGEWTIM 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960352056  82 QLTHPTSCLILTSAIAMKLGLVPFHFWFPEVLQGSPLTTGLILSTAMKLPPMTLLFMTSPSLNPALLTTMAILSTALGGW 161
Cdd:MTH00070  88 NMQTPLPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQISHLLNSNLLIIMGLLSTLIGGW 167
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 2-161 1.47e-70

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 216.21  E-value: 1.47e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960352056   2 IFITSLLLGTTITISSNHWITAWAGLEINTLAILPLISKSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWHTGQWDIT 81
Cdd:MTH00135   8 ILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWLTGQWDIQ 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960352056  82 QLTHPTSCLILTSAIAMKLGLVPFHFWFPEVLQGSPLTTGLILSTAMKLPPMTLLFMTSPSlNPALLTTMAILSTALGGW 161
Cdd:MTH00135  88 QMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPT-NPTLLITLGLTSTLVGGW 166
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-161 9.19e-64

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 198.92  E-value: 9.19e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960352056   1 LIFITSLLLGTTITISSNHWITAWAGLEINTLAILPLISKSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWHTGQWDI 80
Cdd:MTH00105   7 IIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMYSGQWTI 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960352056  81 TQLTHPTSCLILTSAIAMKLGLVPFHFWFPEVLQGSPLTTGLILSTAMKLPPMTLLFMTSPSLNPALLTTMAILSTALGG 160
Cdd:MTH00105  87 TKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAILSILIGG 166


                 .
gi 960352056 161 W 161
Cdd:MTH00105 167 W 167
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 1-161 1.13e-50

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 165.14  E-value: 1.13e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960352056   1 LIFITSLLLGTTITISSNHWITAWAGLEINTLAILPLISKSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWHTGQWDI 80
Cdd:MTH00200   7 PLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWTSGQWGI 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960352056  81 TQLTHPTSCLILTSAIAMKLGLVPFHFWFPEVLQGSPLTTGLILSTAMKLPPMTLLFMTSPSLNPALLTTMAILSTALGG 160
Cdd:MTH00200  87 SEMLGPLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIQLAPALNSNILLLLGLLSVLVGG 166


                 .
gi 960352056 161 W 161
Cdd:MTH00200 167 W 167
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 1-161 2.07e-48

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 159.33  E-value: 2.07e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960352056   1 LIFITSLLLGTTITISSNHWITAWAGLEINTLAILPLISKSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWHTGQWDI 80
Cdd:MTH00041   7 IFLITSIILGTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWLSGSWSI 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960352056  81 TQLTHPTSCLILTSAIAMKLGLVPFHFWFPEVLQGSPLTTGLILSTAMKLPPMTLLFMTSPSLNPALLTTMAILSTALGG 160
Cdd:MTH00041  87 NGPLNTLSSIIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNLLNSNILILCGILSVLVGG 166


                 .
gi 960352056 161 W 161
Cdd:MTH00041 167 W 167
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-159 7.40e-30

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 110.68  E-value: 7.40e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960352056   1 LIFITSLLLGTTITISSNHWITAWAGLEINTLAILPLISKSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWhtgqwdI 80
Cdd:MTH00160   8 LLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNML------N 81

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 960352056  81 TQLTHPTSCLILTSAIAMKLGLVPFHFWFPEVLQGSPLTTGLILSTAMKLPPMTLLFMTspsLNPALLTTMAILSTALG 159
Cdd:MTH00160  82 LMLFNNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYL---INNNFIIIIIILSAIIG 157
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 1-160 1.44e-25

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 99.19  E-value: 1.44e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960352056   1 LIFITSLLLGTTITISSNHWITAWAGLEINTLAILPLISKSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWHTGQWDI 80
Cdd:MTH00144   7 LLFLFLMVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNLSFSWFS 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960352056  81 TqlthptscLILTSAIAMKLGLVPFHFWFPEVLQGSPLTTGLILSTAMKLPPMTLLFMTSPSLNPA-LLTTMAILSTALG 159
Cdd:MTH00144  87 M--------SLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLDLYWLAyLLCVISVLSALVG 158


                 .
gi 960352056 160 G 160
Cdd:MTH00144 159 S 159
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 1-160 2.23e-22

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 90.99  E-value: 2.23e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960352056   1 LIFITSLLLGTTITISSNHWITAWAGLEINTLAILPLISKSHHPRAIEAATKYFLTQAAASALVLFSSmtnawhTGQWDI 80
Cdd:MTH00011   9 FLFSSTMTLGTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGM------TMMWSF 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960352056  81 TQLTHPTSCLILTSAIAMKLGLVPFHFWFPEVLQGSPLTTGLILSTAMKLPPMTLLFMTSPSLNPALLTTMAILSTALGG 160
Cdd:MTH00011  83 PSLLKNITALMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNILPMMTSMAAMSALAGG 162
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 2-160 1.92e-16

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 74.71  E-value: 1.92e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960352056   2 IFITSLLLGTTITISSNHWITAWAGLEINTLAILPLISKSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWHTgqwdit 81
Cdd:MTH00197   2 LFLFIIFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLMGGSLSFSNL------ 75

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 960352056  82 qLTHPTSCLILTSAIAMKLGLVPFHFWFPEVLQGSPLTTGLILSTAMKLPPMTLLfmTSPSLNPALLTTMAILSTALGG 160
Cdd:MTH00197  76 -YLSLLSVVLVILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPLLIL--AFNSSSFMGLLICSVLSSLIGG 151
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 8-159 4.20e-15

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 71.30  E-value: 4.20e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960352056   8 LLGTTITISSNHWITAWAGLEINTLAILPLIS-KSHHPRAIEAATKYFLTQAAASALVLF-SSMTNAWhTGQWDITQLTH 85
Cdd:COG1007  112 TLGMMLMASANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLGALSSGFLLYgISLLYGA-TGSLNLAGIAA 190

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960352056  86 PTS------------CLILTSAIAMKLGLVPFHFWFPEVLQGSPLTTGLILSTAMKL----PPMTLLFMTSPSLNPA--- 146
Cdd:COG1007  191 ALAagganspllllgLVLVLAGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIaafaALLRLLVEAFPGLAADwql 270

                        170
                 ....*....|...
gi 960352056 147 LLTTMAILSTALG 159
Cdd:COG1007  271 LLAVLAVLSMTVG 283
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
8-159 4.25e-14

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 68.31  E-value: 4.25e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960352056   8 LLGTTITISSNHWITAWAGLEINTLAILPLIS-KSHHPRAIEAATKYFLTQAAASALVL--------------FSSMTNA 72
Cdd:PRK05777 113 LLGMMVMVSANDLLTLFLGLELLSLPLYALAAlRRDRRRSLEAAIKYFVLGALASGFLLygmsllygatgslsFAGIAKA 192

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960352056  73 WHTGQWDITQLThpTSCLILTSAIAMKLGLVPFHFWFPEVLQGSPLTTGLILSTAMKL----PPMTLLFMTSPSLNPA-- 146
Cdd:PRK05777 193 LADGSGNSLLLL--FGLVFLLVGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIaafaVLLRLLVVAFGGLSEDwq 270

                        170
                 ....*....|....
gi 960352056 147 -LLTTMAILSTALG 159
Cdd:PRK05777 271 qVLAIIAIASMLVG 284
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 7-160 7.21e-13

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 64.67  E-value: 7.21e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960352056   7 LLLGTTITISSNHWITAWAGLEINTLAILPLI-SKSHHPRAIEAATKYFLTQAAASALVLFS-------------SMTNA 72
Cdd:MTH00196   2 VALGILCLISSSNWLSVYLAIELQTLSLFILIaQNRGSGYSAEAGLKYFVLGALSSGLFLFGcallcgttgglhlSYINL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960352056  73 WHTGQWDITQLTHPTSCLILTSAIAMKLGLVPFHFWFPEVLQGSPLTTGLILSTAMKLPPMTLLFMTSPSLNPAL-LTTM 151
Cdd:MTH00196  82 VLNSGQSFSSVSVPIGYLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSIGLNVNILLiGGLF 161


                 ....*....
gi 960352056 152 AILSTALGG 160
Cdd:MTH00196 162 SLFVGAIGA 170
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 8-130 2.50e-12

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 63.43  E-value: 2.50e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960352056    8 LLGTTITISSNHWITAWAGLEINTLAILPLIS-KSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWHTGQWDITQLTHP 86
Cdd:TIGR01770 112 LLGIFLLVSSNDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLNFEDLLLF 191

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 960352056   87 TSCLILT------------SAIAMKLGLVPFHFWFPEVLQGSPLTTGLILSTAMKL 130
Cdd:TIGR01770 192 LSNGMLNisllllgivlilVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKI 247
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 2-160 4.23e-11

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 60.03  E-value: 4.23e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960352056   2 IFITSLLLGTTITISSNHWITAWAGLEINTLAILPLIS-KSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWHTGQWDI 80
Cdd:MTH00199 101 ILILIVALGSLLLVSSINWLSIYLAIELQTLTLFILVAlKRDSAYSTEAGLKYFVLGAVSSGLFLFGCALLYGLTGETSI 180

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960352056  81 ----TQLTHPTSCLILTSAIAMKLGLVPFHFWFPEVLQGSPLTTGLILSTAMKLPPMTLLFMTSPSLNPALLTtmAILST 156
Cdd:MTH00199 181 qginSILTGDVGKILITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVTNVVLIC--AVLSI 258


                 ....
gi 960352056 157 ALGG 160
Cdd:MTH00199 259 IYGA 262
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 17-141 8.64e-10

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 55.78  E-value: 8.64e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960352056   17 SNHWITAWAGLEINTLAILPLI-SKSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWHTGQWDITQL-----------T 84
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIgYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELskaltgglnssG 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 960352056   85 HPTSCLILTSAIAMKLGLVPFHFWFPEVLQGSPLTTGLIL-STAMKLPPMTLLFMTSP 141
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLaATLVKAGGYGLIRRSLL 138
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 9-161 4.85e-08

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 51.01  E-value: 4.85e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960352056   9 LGTTITISSNHWITAWAGLEINTLAILPLISKSHHPRAI---------EAATKYFLTQAAASALVLFSSMTNAWHTGQ-- 77
Cdd:MTH00198 199 LGGLLLIESANWLTIYLALEFQTLALFILAGEGSQPGSHfpspgntppESGLKYWILGAMSSGFYLFGCALYFGFTGNeg 278

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960352056  78 --WDITQLTHPTS----------CLILTSAIAMKLGLVPFHFWFPEVLQGSPLTTGLILSTAMKLPPMTLLfmTSPSLNP 145
Cdd:MTH00198 279 mlGTILSATLETTnielrqgslgYLFITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKFTVYILL--TSLVITS 356

                        170
                 ....*....|....*.
gi 960352056 146 ALLTTMAILSTALGGW 161
Cdd:MTH00198 357 KLLLSVAIISLVVGAF 372
ndhB CHL00049
NADH dehydrogenase subunit 2
 1-159 7.82e-08

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 50.39  E-value: 7.82e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960352056   1 LIFITSLLLGTTITISSNHWITAWAGLEINTLAILPLISKSHHP-RAIEAATKYFLTQAAASALVL--FSSM--TNAWHT 75
Cdd:CHL00049 114 LLFVLTATLGGMFLCGANDLITIFVALECLSLCSYLLSGYTKKDvRSNEATMKYLLMGGASSSILVygFSWLygLSGGEI 193

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960352056  76 GQWDI------TQLTHPTSCLI----LTSAIAMKLGLVPFHFWFPEVLQGSPL-----------TTGLILSTAMklppMT 134
Cdd:CHL00049 194 ELQEIvnglinTQMYNSPGISIalifITVGIGFKLSLAPFHQWTPDVYEGSPTpvvaflsvtskVAASALATRI----FD 269

                        170       180
                 ....*....|....*....|....*
gi 960352056 135 LLFMTSPSLNPALLTTMAILSTALG 159
Cdd:CHL00049 270 IPFYFSSNEWHLLLEILAILSMILG 294
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
44-159 1.28e-06

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 46.97  E-value: 1.28e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960352056  44 PRAIEAATKYFLTQAAASALVLF-SSMTNAWHTGQwdiTQL--------THPTSCLILT-----SAIAMKLGLVPFHFWF 109
Cdd:PRK02504 157 PRSNEAALKYLLIGAASSAIFLYgSSLLYGLSGGS---TQLsaialaliTSPSLGLALAlvfviAGIAFKISAVPFHQWT 233

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 960352056 110 PEVLQGSPLTTGLILSTAMKLP----PMTLLFMTSPSLNP---ALLTTMAILSTALG 159
Cdd:PRK02504 234 PDVYEGSPTPVVAFLSVGSKAAgfalAIRLLVTAFPSFDEqwkLLFTALAILSMVLG 290
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 7-110 1.89e-06

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 46.29  E-value: 1.89e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960352056   7 LLLGTTITISSNHWITAWAGLEINTLAILPLISKSHHPRAIEAATKYFLTQAAASALVLFSSMTNAWHTGQWDITQLTH- 85
Cdd:COG0651  116 LLAGMNGAFLTGDLFNLFVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYGATGTLNMADLAAr 195

                         90       100       110
                 ....*....|....*....|....*....|....
gi 960352056  86 ---------PTSCLILTSAIAMKLGLVPFHFWFP 110
Cdd:COG0651  196 laeldpgllLAAFALLLVGFGIKAALFPLHFWLP 229
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 43-125 1.80e-03

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 37.75  E-value: 1.80e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960352056  43 HPRAIEAATKYFLTQAAASALVLFSSMTNAWHTGQW--DITQLTH-----PTSCLILTS---AIAMKLGLVPFHFWFPEV 112
Cdd:COG1008  156 GERRIYAAIKFFLYTLAGSLLMLVAILALYFLAGALtfDIAELAAaplplTAQLLLFLAffiAFAVKVPMFPFHTWLPDA 235

                         90
                 ....*....|...
gi 960352056 113 LQGSPLTTGLILS 125
Cdd:COG1008  236 HVEAPTAGSVLLA 248
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 27-111 2.36e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 37.38  E-value: 2.36e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 960352056  27 LEINTLAILPLIS-KSHHPRAIEAATKYFLTQAAASALVLFS---------SMTNAWHTGQWDITQLTHPTSCL-ILTSA 95
Cdd:PRK08376 150 LEIMSIASYALVAfRNDTWEAIEAGIKYMFVGSLASSMVLLGiallygqygTLNMAYLAVKMSENPTVVAKIALaLFIAG 229

                         90
                 ....*....|....*.
gi 960352056  96 IAMKLGLVPFHFWFPE 111
Cdd:PRK08376 230 LAMKSGAVPVHMWLPD 245
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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