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Conserved domains on  [gi|349501038|ref|NP_001002666|]
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excitatory amino acid transporter 3 [Danio rerio]

Protein Classification

dicarboxylate/amino acid:cation symporter( domain architecture ID 10003465)

dicarboxylate/amino acid:cation symporter facilitates H+ or Na+ symport with C4-dicarboxylates, dicarboxylic amino acids (aspartate, glutamate) or other amino acids; belongs to the sodium:dicarboxylate symporter family

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
19-477 3.08e-124

Na+/H+-dicarboxylate symporter [Energy production and conversion];


:

Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 369.83  E-value: 3.08e-124
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 349501038  19 KRNWILIATIIAVILGIGLGVVVRDYTSltqlekQYFGFPGEILMRMLKMVILPLIVSSMITGVAAL-DSEVSGRIGLRA 97
Cdd:COG1301    1 FKLSLTLQILIALVLGILLGLLLPELVA------AVLKPLGDIFINLLKMIVVPLVFFSIVVGIASLgDLKKLGRIGGKT 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 349501038  98 VVYYISTTIIAVILGIVLVMTIKPGVSQSADNIDREGTTPnvTTVETLLDLIRNMFPENLVQAcfqqyktqrreieptkp 177
Cdd:COG1301   75 LLYFLVTTTIALVIGLVVANLFQPGAGLNLDLADAAAAEA--AEAPSLLDFLLNIIPSNIFEA----------------- 135

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 349501038 178 sinttnatafppfttiistvaqnltkdykivgsYSDGiNVLGLIVFCVTFGLVIGKMGERGRILLEFFDALNEATMRIVQ 257
Cdd:COG1301  136 ---------------------------------FAEG-NMLQIIFFAILFGIALAALGEKGKPLLDFFESLSEVMFKIVG 181

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 349501038 258 IIMCYMPIGIFFLIAAKIIEVDdWEIFRKLGLYMVTVLSGLAIHSIIFLPLIYFVFVRKNPFTFTLGMAQALVTALMISS 337
Cdd:COG1301  182 WVMKLAPIGVFALIAATVAKYG-LDALGSLGKLVLTVYLALLLHLFVVLPLILRLLTGLSPLKFLRAIRPALLLAFSTSS 260

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 349501038 338 SSATLPVTFRCAEENNRIDKRITRFVLPVGATINMDGTALYEAVASIFIAQLNNYDLNAGQIVTISITATVASIGAAGVP 417
Cdd:COG1301  261 SEATLPVTMEKAEEKLGVSKSVASFVLPLGATINMDGTAIYQAVAALFIAQAYGIDLSLGQQLTIVLTAVLASIGAAGVP 340

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 349501038 418 NAGMVTMVIVLTAVGLPADDVTLIIAVDWLLDRFRTMINVLGDAYGAGIVQKlSKRELER 477
Cdd:COG1301  341 GAGLVMLAAVLSAVGLPLEGIALILGIDRILDMARTAVNVTGDAVATVVVAK-WEGELDR 399
 
Name Accession Description Interval E-value
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
19-477 3.08e-124

Na+/H+-dicarboxylate symporter [Energy production and conversion];


Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 369.83  E-value: 3.08e-124
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 349501038  19 KRNWILIATIIAVILGIGLGVVVRDYTSltqlekQYFGFPGEILMRMLKMVILPLIVSSMITGVAAL-DSEVSGRIGLRA 97
Cdd:COG1301    1 FKLSLTLQILIALVLGILLGLLLPELVA------AVLKPLGDIFINLLKMIVVPLVFFSIVVGIASLgDLKKLGRIGGKT 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 349501038  98 VVYYISTTIIAVILGIVLVMTIKPGVSQSADNIDREGTTPnvTTVETLLDLIRNMFPENLVQAcfqqyktqrreieptkp 177
Cdd:COG1301   75 LLYFLVTTTIALVIGLVVANLFQPGAGLNLDLADAAAAEA--AEAPSLLDFLLNIIPSNIFEA----------------- 135

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 349501038 178 sinttnatafppfttiistvaqnltkdykivgsYSDGiNVLGLIVFCVTFGLVIGKMGERGRILLEFFDALNEATMRIVQ 257
Cdd:COG1301  136 ---------------------------------FAEG-NMLQIIFFAILFGIALAALGEKGKPLLDFFESLSEVMFKIVG 181

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 349501038 258 IIMCYMPIGIFFLIAAKIIEVDdWEIFRKLGLYMVTVLSGLAIHSIIFLPLIYFVFVRKNPFTFTLGMAQALVTALMISS 337
Cdd:COG1301  182 WVMKLAPIGVFALIAATVAKYG-LDALGSLGKLVLTVYLALLLHLFVVLPLILRLLTGLSPLKFLRAIRPALLLAFSTSS 260

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 349501038 338 SSATLPVTFRCAEENNRIDKRITRFVLPVGATINMDGTALYEAVASIFIAQLNNYDLNAGQIVTISITATVASIGAAGVP 417
Cdd:COG1301  261 SEATLPVTMEKAEEKLGVSKSVASFVLPLGATINMDGTAIYQAVAALFIAQAYGIDLSLGQQLTIVLTAVLASIGAAGVP 340

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 349501038 418 NAGMVTMVIVLTAVGLPADDVTLIIAVDWLLDRFRTMINVLGDAYGAGIVQKlSKRELER 477
Cdd:COG1301  341 GAGLVMLAAVLSAVGLPLEGIALILGIDRILDMARTAVNVTGDAVATVVVAK-WEGELDR 399
SDF pfam00375
Sodium:dicarboxylate symporter family;
23-470 6.95e-119

Sodium:dicarboxylate symporter family;


Pssm-ID: 425646 [Multi-domain]  Cd Length: 388  Bit Score: 355.29  E-value: 6.95e-119
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 349501038   23 ILIATIIAVILGIGLGVVVRDYTSltqlekqYFGFPGEILMRMLKMVILPLIVSSMITGVAAL-DSEVSGRIGLRAVVYY 101
Cdd:pfam00375   1 LLLQILIALVLGILIGLFFPELAA-------WLKPLGDLFIRLLKMIIVPLIFASIISGIASLgDGKKLGKLGGKTLLYF 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 349501038  102 ISTTIIAVILGIVLVMTIKPGVSQSADNIDREGTtpNVTTVETLLDLIRNMFPENLVQACFQQyktqrreieptkpsint 181
Cdd:pfam00375  74 LVTTAIAALIGLLVANVFQPGSGLALIAASLKEA--KAAEAPSLLDFILNIIPSNIFEALAEG----------------- 134

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 349501038  182 tnatafppfttiistvaqnltkdykivgsysdgiNVLGLIVFCVTFGLVIGKMGERGRILLEFFDALNEATMRIVQIIMC 261
Cdd:pfam00375 135 ----------------------------------NVLAVIVFAILFGIALAALGEKGEPLLNFIESLQEVMMKVIGWVMK 180

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 349501038  262 YMPIGIFFLIAAKIIEVDdWEIFRKLGLYMVTVLSGLAIHSIIFLPLIYFVFVRKNPFTFTLGMAQALVTALMISSSSAT 341
Cdd:pfam00375 181 LAPIGVFALIANTVGTYG-LGILSSLAKFLLVVYLGLAIHLLIVYPLLIKFLGKVNPFKFLKKMLPALLTAFSTASSAAT 259

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 349501038  342 LPVTFRCAEENNRIDKRITRFVLPVGATINMDGTALYEAVASIFIAQLNNYDLNAGQIVTISITATVASIGAAGVPNAGM 421
Cdd:pfam00375 260 LPVTLECAEKNLGVSESIASFVLPLGATINMDGTAIYLAVAAIFIAQAYGVDLSFGQQLTLVLTATLASIGAAGVPGGGL 339

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*....
gi 349501038  422 VTMVIVLTAVGLPADDVTLIIAVDWLLDRFRTMINVLGDAYGAGIVQKL 470
Cdd:pfam00375 340 VALGLVLSALGLPLEGIALILAIDRLLDMFRTAVNVTGDAAAAVIVAKL 388
gltP PRK11283
glutamate/aspartate:proton symporter; Provisional
 28-469 1.38e-43

glutamate/aspartate:proton symporter; Provisional


Pssm-ID: 183075 [Multi-domain]  Cd Length: 437  Bit Score: 160.31  E-value: 1.38e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 349501038  28 IIAVILGIGLGVVVRDYTSLTQLEKQYFGFP-GEILMRMLKMVILPLIVSSMITGVAAL-DSEVSGRIGLRAVVYYISTT 105
Cdd:PRK11283  13 LIALVLGILLGAYLHYHSDSRDWLVSNLLSPaGDIFIHLIKMIVVPIVISTLIVGIAGVgDAKQLGRIGAKTIIYFEVIT 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 349501038 106 IIAVILGIVLVMTIKPGVSqsadnIDREgttpnvttvetlldlirnmfpeNLVQACFQQYKTQRREIEPTKPSInttnat 185
Cdd:PRK11283  93 TVAIILGITLANVFQPGAG-----IDMS----------------------QLATVDISKYQSTTEEVQSHSHGL------ 139

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 349501038 186 afppFTTIISTVAQNltkdykIVGSYSDGiNVLGLIVFCVTFGLVIGKMGERGRI-LLEFFDALNEATMRIVQIIMCYMP 264
Cdd:PRK11283 140 ----MGTILSLIPTN------IFASMAKG-EMLPIIFFSVLFGLGLSSLPATHREpLVTVFRSVSETMFKVTHMVMRYAP 208

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 349501038 265 IGIFFLIAAKIIEvddweiFRKLGLYMVTVLSGLAIHSIIFLPLIYFVFVRK----NPFTFTLGMAQALVTALMISSSSA 340
Cdd:PRK11283 209 VGVFALIAVTVAN------FGFASLWPLAKLVLLVYFAILFFALVVLGIVARlcglSIWILIRILKDELILAYSTASSET 282

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 349501038 341 TLPvtfRCAE--ENNRIDKRITRFVLPVGATINMDGTALYEAVASIFIAQLNNYDLNAGQIVTISITATVASIGAAGVPN 418
Cdd:PRK11283 283 VLP---RIIEkmEAYGAPKSITSFVVPTGYSFNLDGSTLYQSIAAIFIAQLYGIDLSIWQEIILVLTLMVTSKGIAGVPG 359

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|.
gi 349501038 419 AGMVTMVIVLTAVGLPADDVTLIIAVDWLLDRFRTMINVLGDAYGAGIVQK 469
Cdd:PRK11283 360 VSFVVLLATLGSVGIPLEGLAFIAGVDRILDMARTALNVVGNALAVLVIAK 410
 
Name Accession Description Interval E-value
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
19-477 3.08e-124

Na+/H+-dicarboxylate symporter [Energy production and conversion];


Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 369.83  E-value: 3.08e-124
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 349501038  19 KRNWILIATIIAVILGIGLGVVVRDYTSltqlekQYFGFPGEILMRMLKMVILPLIVSSMITGVAAL-DSEVSGRIGLRA 97
Cdd:COG1301    1 FKLSLTLQILIALVLGILLGLLLPELVA------AVLKPLGDIFINLLKMIVVPLVFFSIVVGIASLgDLKKLGRIGGKT 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 349501038  98 VVYYISTTIIAVILGIVLVMTIKPGVSQSADNIDREGTTPnvTTVETLLDLIRNMFPENLVQAcfqqyktqrreieptkp 177
Cdd:COG1301   75 LLYFLVTTTIALVIGLVVANLFQPGAGLNLDLADAAAAEA--AEAPSLLDFLLNIIPSNIFEA----------------- 135

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 349501038 178 sinttnatafppfttiistvaqnltkdykivgsYSDGiNVLGLIVFCVTFGLVIGKMGERGRILLEFFDALNEATMRIVQ 257
Cdd:COG1301  136 ---------------------------------FAEG-NMLQIIFFAILFGIALAALGEKGKPLLDFFESLSEVMFKIVG 181

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 349501038 258 IIMCYMPIGIFFLIAAKIIEVDdWEIFRKLGLYMVTVLSGLAIHSIIFLPLIYFVFVRKNPFTFTLGMAQALVTALMISS 337
Cdd:COG1301  182 WVMKLAPIGVFALIAATVAKYG-LDALGSLGKLVLTVYLALLLHLFVVLPLILRLLTGLSPLKFLRAIRPALLLAFSTSS 260

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 349501038 338 SSATLPVTFRCAEENNRIDKRITRFVLPVGATINMDGTALYEAVASIFIAQLNNYDLNAGQIVTISITATVASIGAAGVP 417
Cdd:COG1301  261 SEATLPVTMEKAEEKLGVSKSVASFVLPLGATINMDGTAIYQAVAALFIAQAYGIDLSLGQQLTIVLTAVLASIGAAGVP 340

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 349501038 418 NAGMVTMVIVLTAVGLPADDVTLIIAVDWLLDRFRTMINVLGDAYGAGIVQKlSKRELER 477
Cdd:COG1301  341 GAGLVMLAAVLSAVGLPLEGIALILGIDRILDMARTAVNVTGDAVATVVVAK-WEGELDR 399
SDF pfam00375
Sodium:dicarboxylate symporter family;
23-470 6.95e-119

Sodium:dicarboxylate symporter family;


Pssm-ID: 425646 [Multi-domain]  Cd Length: 388  Bit Score: 355.29  E-value: 6.95e-119
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 349501038   23 ILIATIIAVILGIGLGVVVRDYTSltqlekqYFGFPGEILMRMLKMVILPLIVSSMITGVAAL-DSEVSGRIGLRAVVYY 101
Cdd:pfam00375   1 LLLQILIALVLGILIGLFFPELAA-------WLKPLGDLFIRLLKMIIVPLIFASIISGIASLgDGKKLGKLGGKTLLYF 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 349501038  102 ISTTIIAVILGIVLVMTIKPGVSQSADNIDREGTtpNVTTVETLLDLIRNMFPENLVQACFQQyktqrreieptkpsint 181
Cdd:pfam00375  74 LVTTAIAALIGLLVANVFQPGSGLALIAASLKEA--KAAEAPSLLDFILNIIPSNIFEALAEG----------------- 134

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 349501038  182 tnatafppfttiistvaqnltkdykivgsysdgiNVLGLIVFCVTFGLVIGKMGERGRILLEFFDALNEATMRIVQIIMC 261
Cdd:pfam00375 135 ----------------------------------NVLAVIVFAILFGIALAALGEKGEPLLNFIESLQEVMMKVIGWVMK 180

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 349501038  262 YMPIGIFFLIAAKIIEVDdWEIFRKLGLYMVTVLSGLAIHSIIFLPLIYFVFVRKNPFTFTLGMAQALVTALMISSSSAT 341
Cdd:pfam00375 181 LAPIGVFALIANTVGTYG-LGILSSLAKFLLVVYLGLAIHLLIVYPLLIKFLGKVNPFKFLKKMLPALLTAFSTASSAAT 259

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 349501038  342 LPVTFRCAEENNRIDKRITRFVLPVGATINMDGTALYEAVASIFIAQLNNYDLNAGQIVTISITATVASIGAAGVPNAGM 421
Cdd:pfam00375 260 LPVTLECAEKNLGVSESIASFVLPLGATINMDGTAIYLAVAAIFIAQAYGVDLSFGQQLTLVLTATLASIGAAGVPGGGL 339

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*....
gi 349501038  422 VTMVIVLTAVGLPADDVTLIIAVDWLLDRFRTMINVLGDAYGAGIVQKL 470
Cdd:pfam00375 340 VALGLVLSALGLPLEGIALILAIDRLLDMFRTAVNVTGDAAAAVIVAKL 388
gltP PRK11283
glutamate/aspartate:proton symporter; Provisional
 28-469 1.38e-43

glutamate/aspartate:proton symporter; Provisional


Pssm-ID: 183075 [Multi-domain]  Cd Length: 437  Bit Score: 160.31  E-value: 1.38e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 349501038  28 IIAVILGIGLGVVVRDYTSLTQLEKQYFGFP-GEILMRMLKMVILPLIVSSMITGVAAL-DSEVSGRIGLRAVVYYISTT 105
Cdd:PRK11283  13 LIALVLGILLGAYLHYHSDSRDWLVSNLLSPaGDIFIHLIKMIVVPIVISTLIVGIAGVgDAKQLGRIGAKTIIYFEVIT 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 349501038 106 IIAVILGIVLVMTIKPGVSqsadnIDREgttpnvttvetlldlirnmfpeNLVQACFQQYKTQRREIEPTKPSInttnat 185
Cdd:PRK11283  93 TVAIILGITLANVFQPGAG-----IDMS----------------------QLATVDISKYQSTTEEVQSHSHGL------ 139

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 349501038 186 afppFTTIISTVAQNltkdykIVGSYSDGiNVLGLIVFCVTFGLVIGKMGERGRI-LLEFFDALNEATMRIVQIIMCYMP 264
Cdd:PRK11283 140 ----MGTILSLIPTN------IFASMAKG-EMLPIIFFSVLFGLGLSSLPATHREpLVTVFRSVSETMFKVTHMVMRYAP 208

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 349501038 265 IGIFFLIAAKIIEvddweiFRKLGLYMVTVLSGLAIHSIIFLPLIYFVFVRK----NPFTFTLGMAQALVTALMISSSSA 340
Cdd:PRK11283 209 VGVFALIAVTVAN------FGFASLWPLAKLVLLVYFAILFFALVVLGIVARlcglSIWILIRILKDELILAYSTASSET 282

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 349501038 341 TLPvtfRCAE--ENNRIDKRITRFVLPVGATINMDGTALYEAVASIFIAQLNNYDLNAGQIVTISITATVASIGAAGVPN 418
Cdd:PRK11283 283 VLP---RIIEkmEAYGAPKSITSFVVPTGYSFNLDGSTLYQSIAAIFIAQLYGIDLSIWQEIILVLTLMVTSKGIAGVPG 359

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|.
gi 349501038 419 AGMVTMVIVLTAVGLPADDVTLIIAVDWLLDRFRTMINVLGDAYGAGIVQK 469
Cdd:PRK11283 360 VSFVVLLATLGSVGIPLEGLAFIAGVDRILDMARTALNVVGNALAVLVIAK 410
PRK01663 PRK01663
C4-dicarboxylate transporter DctA; Reviewed
 28-495 1.24e-37

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 234968 [Multi-domain]  Cd Length: 428  Bit Score: 143.50  E-value: 1.24e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 349501038  28 IIAVILGIGLGVVVRDY-TSLTQLekqyfgfpGEILMRMLKMVILPLIVSSMITGVAAL-DSEVSGRIGLRAVVYYISTT 105
Cdd:PRK01663  14 LVAIIIGILLGHFYPELgAQMKPL--------GDGFIKLIKMIIAPIIFCTVVTGIAGMgDMKKVGRVGGKALLYFEIVS 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 349501038 106 IIAVILGIVLVMTIKPGVSQsadNIDregttpnvttvetlldlirnmfPENLVQACFQQYKTQRREieptkpsintTNAT 185
Cdd:PRK01663  86 TIALIIGLIVVNVVQPGAGM---NID----------------------PATLDAKAVAQYAAQAHE----------QGTV 130

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 349501038 186 AFppFTTIISTvaqnltkdyKIVGSYSDGiNVLGLIVFCVTFGLVIGKMGERGRILLEFFDALNEATMRIVQIIMCYMPI 265
Cdd:PRK01663 131 DF--LMDIIPT---------TVVGAFASG-DILQVLLFAVLFGFALARLGEKGKPVFDFIESLSHVLFGIVNMIMKLAPI 198

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 349501038 266 GIFFLIAAKIievddweifrklGLYMVTVLSGLAIHSIIF-LPLIYFVFV------RKNPFT---FTLGMAQALVTALMI 335
Cdd:PRK01663 199 GAFGAMAFTI------------GKYGVGSLVQLGQLIGCFyITCILFVFVvlgaiaRLTGFSifkFIRYIKEELLIVLGT 266

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 349501038 336 SSSSATLPVTFRcAEENNRIDKRITRFVLPVGATINMDGTALYEAVASIFIAQLNNYDLNAGQIVTISITATVASIGAAG 415
Cdd:PRK01663 267 SSSESALPRMME-KMEKLGCKKSVVGLVIPTGYSFNLDGTSIYLTMAAVFIAQATNTPLSIGHQITLLAVLLLTSKGAAG 345

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 349501038 416 VPNAGMVTMVIVLTAVG-LPADDVTLIIAVDWLLDRFRTMINVLGDAYgAGIVQKLSKRELERMDLTSDVDAANPFALET 494
Cdd:PRK01663 346 VTGSGFIVLAATLSAVPhIPVAGLALILGIDRFMSEARALTNLIGNGV-ATVVVAKWEKELDREKLDRVLNGRAPDGKTE 424


                 .
gi 349501038 495 T 495
Cdd:PRK01663 425 E 425
PRK13027 PRK13027
C4-dicarboxylate transporter DctA; Reviewed
 28-461 4.32e-37

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 183850 [Multi-domain]  Cd Length: 421  Bit Score: 141.73  E-value: 4.32e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 349501038  28 IIAVILGIGLGVVVRDYT-SLTQLekqyfgfpGEILMRMLKMVILPLIVSSMITGVA-ALDSEVSGRIGLRAVVYYISTT 105
Cdd:PRK13027  13 VIALVLGVALGAFFPHFAeSLKPL--------GDGFIKLIKMLIGPIVFCVVVSGIAgAGDLKKVGRVGLKAVIYFEVMT 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 349501038 106 IIAVILGIVLVMTIKPGVSQsadNIDregttpnvttvetlldlirnmfPENLVQACFQQYKTQRREIEPTkpsinttnaT 185
Cdd:PRK13027  85 TIALVIGLVLAYLTGPGVGM---NID----------------------LRSLDAASLAGYAKNAQSLKGT---------A 130

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 349501038 186 AFppFTTIISTVAqnltkdykiVGSYSDGiNVLGLIVFCVTFGLVIGKMGERGRILLEFFDALNEATMRIVQIIMCYMPI 265
Cdd:PRK13027 131 GF--LLKLIPTTA---------VDAFAKG-DILQVLLFSVLFGSALSLLGERAKRVNRLIDELSHVLFRIMGFIIKLAPL 198

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 349501038 266 GIFFLIAAKIievddweifrklGLYMVTVLSGLAIHSIIF-LPLIYFVFV------RKNPFT---FTLGMAQALVTALMI 335
Cdd:PRK13027 199 GVLGAIAFTT------------GKYGVGSLKQLGMLVAVFyLTCFVFVVVvlgavmRLAGFSvfkLIRYLREELLIVLGT 266

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 349501038 336 SSSSATLPVTFRcAEENNRIDKRITRFVLPVGATINMDGTALYEAVASIFIAQLNNYDLNAGQIVTISITATVASIGAAG 415
Cdd:PRK13027 267 ASSDAVLPQVMR-KLEHMGIKDSTVGLVIPTGYSFNLDGFSIYLTLAAVFIAQATNTPLSMHDLITILLVSLVTSKGAHG 345

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|....*..
gi 349501038 416 VPNAGMVTMVIVLTAVG-LPADDVTLIIAVDWLLDRFRTMINVLGDA 461
Cdd:PRK13027 346 IPGSAIVILAATLSAIPaIPVLGLVLILPVDWFMGIARALTNLIGNC 392
TcyP COG1823
L-cystine transporter TcyP, sodium:dicarboxylate symporter family [Amino acid transport and ...
 23-467 1.66e-23

L-cystine transporter TcyP, sodium:dicarboxylate symporter family [Amino acid transport and metabolism];


Pssm-ID: 441428  Cd Length: 463  Bit Score: 103.37  E-value: 1.66e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 349501038  23 ILIATIIAVILGIGLGVVVRDYTSLTQLEKQYFGFPGEILMRMLKMVILPLIVSSMITGVAAL-DSEVSGRIGLRAVVYY 101
Cdd:COG1823   34 VFTGLGLGILFGLILQLIYGAGSPVIKQSIDWFNIVGNGYVRLLQMIVMPLVFVSILSAITKLkNASSLGKISGLIIGIL 113

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 349501038 102 ISTTIIAVILGIVLVMTIK---PGVSQSADNIDRegttpnVTTVETLLDLIRNM-FPENLVqacfqqyktqrrEIEPTKP 177
Cdd:COG1823  114 LGTTAIAALVGILVALLFGltaEGLTQGAAETAR------GEALEERLGEVEDLsLPQQIL------------SFIPTNP 175

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 349501038 178 SINTTNATAfppfTTIISTVaqnltkdykIVGSYSdGINVLGlivfcvtfglVIGKMGERGRILLEFFDALNEATMRIVQ 257
Cdd:COG1823  176 FADLTGARP----TSTIAVV---------IFAAFL-GIAALG----------LRRKKPEQAETFLKGIDALQAIVMRLVR 231

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 349501038 258 IIMCYMPIGIFFLIaAKIIEVDDWEIFRKLGLYMVTVLSGLAIHSIIFLPLIyfVFVRKNPFTFTLGMAQALVTALMISS 337
Cdd:COG1823  232 LVLRLTPYGVLALM-TKVVATSDFADILNLGKFVVASYVALIIMFIVHLLLL--ALAGLNPLTYFKKVWPVLTFAFTSRS 308

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 349501038 338 SSATLPVTFRCAEENNRIDKRITRFVLPVGATINMDGTA-LYEAVASIFIAQLNNYD-LNAGQIVTISITATVASIGAAG 415
Cdd:COG1823  309 SAGTIPLNIETQTKRLGVPEGIANFAASFGATIGQNGCAgIYPAMLAVMIAPTVGINpLDPSFILTLIAVVTISSFGVAG 388

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|..
gi 349501038 416 VPNAGMVTMVIVLTAVGLPADDVTLIIAVDWLLDRFRTMINVlGDAYGAGIV 467
Cdd:COG1823  389 VGGGATFAALIVLSAMGLPVALAGLLISIEPLIDMGRTALNV-SGSMTAGTV 439
PRK14695 PRK14695
serine/threonine transporter SstT; Provisional
 172-474 2.59e-12

serine/threonine transporter SstT; Provisional


Pssm-ID: 173158  Cd Length: 319  Bit Score: 67.77  E-value: 2.59e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 349501038 172 IEPTKPSINTTNATAFPPftTIISTVAQNLTkdYKIVGSYSDGI---NVLGLIVFCVTFGLVIGKMGERGRILLEffdAL 248
Cdd:PRK14695  17 IVPIEITLNSANTEIAPP--DGIGQVLSNLL--LKLVDSPVNALltaNYIGILSWAVIFGIAMREASKNSKELLK---TI 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 349501038 249 NEATMRIVQIIMCYMPIGIFFLIAaKIIEVDDWEIFRKLGLYMVTVLSGLAIHSIIFLPLIYFVFVRKNPFTFTLG-MAQ 327
Cdd:PRK14695  90 ADVTSKIVEWIINLAPFGILGLVF-KTISDKGVGSLANYGILLVLLVTTMLFVAPVVNPLIAFFFMRRNPYPLVWNcLRV 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 349501038 328 ALVTALMISSSSATLPVTFRCAEENNrIDKRITRFVLPVGATINMDGTALYEAVASIFIAQLNNYDLNAGQIVTISITAT 407
Cdd:PRK14695 169 SGVTAFFTRSSATNIPVNMKLCHDLG-LNPDTYSVSIPLGSTINMAGVAITINLLTLVTVNTLGIPVDFATAFVLSVVAA 247

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 349501038 408 VASIGAAGVPNAGMVTMVIVLTAVGLPADDVTLIIAVDWLL----DRFRTMINVLGDAYGAGIVQKLSKRE 474
Cdd:PRK14695 248 ISACGASGIAGGSLLLIPVACSLFGISNDIAIQIVGVGFVIgviqDSCETALNSSTDVLFTAVAEYAATRK 318
PRK13628 PRK13628
serine/threonine transporter SstT; Provisional
 174-416 1.23e-11

serine/threonine transporter SstT; Provisional


Pssm-ID: 184190 [Multi-domain]  Cd Length: 402  Bit Score: 66.43  E-value: 1.23e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 349501038 174 PTKPSINTTNATAFPPftTIISTVAQNLTkdYKIVGSYSDGI---NVLGLIVFCVTFGLVIGKMGERGRillEFFDALNE 250
Cdd:PRK13628 105 PSTLVLVASAADISPP--QGIVEVLKTLL--LSLVDNPINALlnaNYIGILAWAIGLGLALRHASDTTK---NVVNDLSE 177

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 349501038 251 ATMRIVQIIMCYMPIGIFFLIAAKIIEVDdweiFRKLGLY--MVTVLSG-LAIHSIIFLPLIYFVFVRKNPFTFTLG-MA 326
Cdd:PRK13628 178 AVSQIVKWVIRFAPIGIFGLVASTLAETG----FSALAGYaqLLAVLVGcMLFVALVVNPLIVFWKIRRNPYPLVFTcLR 253

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 349501038 327 QALVTALMISSSSATLPVTFRCAEENNrIDKRITRFVLPVGATINMDGTALYEAVASIFIAQLNNYDLNAGQIVTISITA 406
Cdd:PRK13628 254 ESGVTAFFTRSSAANIPVNMALCEKLG-LDEDTYSVSIPLGATINMAGAAITITVLTLAAVHTLGIPVDLPTALLLSVVA 332

                        250
                 ....*....|
gi 349501038 407 TVASIGAAGV 416
Cdd:PRK13628 333 AISACGASGV 342
SstT COG3633
Na+/serine and Na+/threonine symporter SstT [Amino acid transport and metabolism];
174-417 1.82e-10

Na+/serine and Na+/threonine symporter SstT [Amino acid transport and metabolism];


Pssm-ID: 442850  Cd Length: 406  Bit Score: 62.88  E-value: 1.82e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 349501038 174 PTKPSINTTNATAFPPftTIISTVAQNLTkdYKIVGSYSDGI---NVLGLIVFCVTFGLVIGKMGERGRillEFFDALNE 250
Cdd:COG3633  104 PTTLTLVAAAADLTPP--GGIGEVLKTLL--LNVVDNPVNALanaNYIGILAWAIGLGLALRHASDTTK---TVLSDLSD 176

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 349501038 251 ATMRIVQIIMCYMPIGIFFLIAAKIIEVDdweiFRKLGLY--MVTVLSG-LAIHSIIFLPLIYFVFVRKNPF--TFTLgM 325
Cdd:COG3633  177 AVSKIVRWVIRFAPLGIFGLVASTVATTG----FSALLGYahLLAVLVGcMLFVALVVNPLIVFLKIRRNPYplVFTC-L 251

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 349501038 326 AQALVTALMISSSSATLPVTFRCAEENNrIDKRITRFVLPVGATINMDGTALYEAVASIFIAQLNNYDLNAGQIVTISIT 405
Cdd:COG3633  252 RESGITAFFTRSSAANIPVNMALCEKLG-LDEDTYSVSIPLGATINMAGAAITITVLTLAAVHTLGIEVDLPTALLLSVV 330

                        250
                 ....*....|..
gi 349501038 406 ATVASIGAAGVP 417
Cdd:COG3633  331 AAVSACGASGVA 342
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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