|
Name |
Accession |
Description |
Interval |
E-value |
| CitT |
COG0471 |
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism]; |
47-519 |
4.34e-88 |
|
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism];
Pssm-ID: 440239 [Multi-domain] Cd Length: 369 Bit Score: 276.26 E-value: 4.34e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 47 LSGLIMASAIEEWNLHRRIALKILMLVGVQPARLILGMMVTTSFLSMWLSNTASTAMMLPIANAILKSLfgqkevrkdps 126
Cdd:COG0471 1 LGGFVLAAALEKTGLGRRIALLLLKRFGGSPLRLLLGLMLATALLSAFISNTARAAMMLPIALSIAAAL----------- 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 127 qeseentaavrrnglhtvptemqflasteakdhpgetevpldlpadsrkEDEYRRNIWKGFLISIPYSASIGGTATLTGT 206
Cdd:COG0471 70 -------------------------------------------------GSEKRSKFGSALLLPIAFAASIGGMGTLIGT 100
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 207 APNLILLGQLKSFFPQcdVVNFGSWFIFAFPLMLLFLLAGWLWISFLYgglsfrgwRKNKSEIrtnaeDRARAVIREEYQ 286
Cdd:COG0471 101 PPNLIAAGLLEEATGI--PISFFEWMLVGLPVALVGLLLLWLVLYRLL--------PPEIKEV-----PGSKEVIREELA 165
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 287 NLGPIKFAEQAVFILFCMFAILLFTRDPKFIPgwaslfnpgflsDAVTGVAIVTILFFFPsqrpslkwwfdfkapntete 366
Cdd:COG0471 166 ELGPLSRREKIALAIFALTVLLWITGSLHGIP------------IAVVALLGAVLLLLTG-------------------- 213
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 367 pLLTWKKAQETVPWNIILLLGGGFAMAKGCEESGLSVWIGGQL-HPLENVPPALAVLLITVVIAFFTEFASNTATIIIFL 445
Cdd:COG0471 214 -VLTWKDAYKSIPWGVLLLFGGGLALGAALEKTGLAAWLADALlPLLGGLSPLLLLLLLALLTLLLTEFASNTATAALLL 292
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 58761541 446 PVLAELAIRLRVHPLYLMIPGTVGCSFAFMLPVSTPPNSIAFASGHLLVKDMVRTGLLMNLMGVLLLSLAMNTW 519
Cdd:COG0471 293 PIAISLAQALGVNPLPLALAVAFAASCAFLLPVGTPPNAIVYGSGYYKFKDFLKVGLPLNLIGLVVLLLLGPLW 366
|
|
| SLC13_permease |
cd01115 |
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been ... |
1-511 |
1.91e-70 |
|
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is related to renal and intestinal Na+/sulfate cotransporters and a few putative bacterial permeases. The SLC13-type proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium and various anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease is composed of 8-13 transmembrane helices.
Pssm-ID: 238535 [Multi-domain] Cd Length: 382 Bit Score: 230.93 E-value: 1.91e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 1 MAVYWCTEALPLSVTALLPIVLFPFMGILPSNKVCPQYFLDTNFLFLSGLIMASAIEEWNLHRRIALKILMLVGVQPARL 80
Cdd:cd01115 7 AAVLFVTEALPLDVTALLVPVLLVLLGVVPPKEAFSGFSDPAVILFLAGFILGAALTRTGLAKRIATKLLKRAGKGERRL 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 81 ILGMMVTTSFLSMWLSNTASTAMMLPIANAILKSLfgqkevrkdpsqeseentaavrrnglhtvPTEMQFLasteakdhp 160
Cdd:cd01115 87 LLLLMLVTAFLSAFMSNTATVAIMLPVALGLAAKL-----------------------------DISPSRL--------- 128
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 161 getevpldlpadsrkedeyrrniwkgfLISIPYSASIGGTATLTGTAPNLILLGQLKSFFPQcdvvnfGSWFIFAFPLML 240
Cdd:cd01115 129 ---------------------------LMPLAFAASIGGMLTLIGTPPNLVASGYLESLGGQ------GFSFFEFTPIGL 175
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 241 LFLLAGWLWISFLYGglsfrgwrknkseirtnaedraravireeyqnlgpikfaeqavfILFCMFAILLFTrdpkfipgw 320
Cdd:cd01115 176 PLLIIGLLYLWFIFR--------------------------------------------LAVLIITIVLLA--------- 202
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 321 ASLFNPGFLSDAVTGVAIVTILFFFPsqrpslkwwfdfkapntetepLLTWKKAQETVPWNIILLLGGGFAMAKGCEESG 400
Cdd:cd01115 203 ALAAITGLLPVSVAIAIGAIVLVFGG---------------------VLLTKEDYKSIDWGIIFLFAGGIPLGKALESSG 261
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 401 LSVWIGGQLHP-LENVPPALAVLLITVVIAFFTEFASNTATIIIFLPVLAELAIRLRVHPLYLMIPGTVGCSFAFMLPVS 479
Cdd:cd01115 262 AAALIAEALISlLGGLPPFAILLLLCLLTLVLTNFISNTATAVLLAPIALSIALSLGLPPEALLLAVAIGASCAFMLPVG 341
|
490 500 510
....*....|....*....|....*....|..
gi 58761541 480 TPPNSIAFASGHLLVKDMVRTGLLMNLMGVLL 511
Cdd:cd01115 342 TPPNAIVLGPGGYKFSDFAKVGLPLSILSLVV 373
|
|
| Na_sulph_symp |
pfam00939 |
Sodium:sulfate symporter transmembrane region; There are also some members in this family that ... |
1-519 |
3.06e-62 |
|
Sodium:sulfate symporter transmembrane region; There are also some members in this family that do not match the Prosite motif, and belong to the subfamily SODIT1.
Pssm-ID: 279307 [Multi-domain] Cd Length: 472 Bit Score: 211.85 E-value: 3.06e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 1 MAVYWCTEALPLSVTALLPIVLFPFMGILPSNKVCPQ----YFLDTNFLFLSGLIMASAIEEWNLHRRIALKILMLVGVQ 76
Cdd:pfam00939 40 TIVGWILEPLPMAVIALFAISLSAILIGTLLAKALSWalsgFSSTTTWLVFGAFFISAAFEKTGLGRRIALVLVKKMGKR 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 77 ParLILGMMVTTSFLSMWLSNTASTAMMLPIANAILKSL---FGqkevrkdpsqeseentaavrrnglhtvptemqflas 153
Cdd:pfam00939 120 T--LGLGYGLVFSDLLLAPATPSNTARAGGIVFPIIMSLppaFG------------------------------------ 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 154 teakdhpgetevpldlpadSRKEDEYRRNIWKGFLISIPYSASIGGTATLTGTAPNLILLGQLKSFFPQcdVVNFGSWFI 233
Cdd:pfam00939 162 -------------------SDPEKGSERRIGAYLMWTVYQSTSITSAMFLTAMAPNLLLLGLMNSILGV--TITWASWFL 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 234 FAFPLMLLFLLAGWLWISFLYGGLSFRGwrknkseirtnaeDRARAVIREEYQNLGPIKFAEQAVFILFCMFAILLFTRD 313
Cdd:pfam00939 221 AAIPPGVILLLLAPLLLYVLYPPEIKSV-------------PDAKAIAKTELKELGPMTFREKALLGLFVLLLLLWIFGG 287
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 314 PKFIpgwaslfnpgflSDAVTGVAIVTILFFFPsqrpslkwwfdfkapntetepLLTWKKA-QETVPWNIILLLGGGFAM 392
Cdd:pfam00939 288 SLNI------------DATTVAIIGLALMLLLR---------------------ILDWKDIvKNKGAWNTLIWLGGLIML 334
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 393 AKGCEESGLSVWIGGQLHPL--ENVPPALAVLLITVVIAFFTEFASNTATIIIFLPVLAELAIRLRVHP-LYLMIPGTVG 469
Cdd:pfam00939 335 ANGLERSGFIEWLGNTLSTSlsGFSPAMAFIIILSLFYLSHYLFASATAHTAAMLPIFAAVAQAIPGAPpLLAALLLGFA 414
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|.
gi 58761541 470 CSFA-FMLPVSTPPNSIAFASGHLLVKDMVRTGLLMNLMGVLLLSLAMNTW 519
Cdd:pfam00939 415 ISLGgFLTPYGTGPGPIYFGSGYLKVKDWWRIGAILTIIGLLILLLLGNWW 465
|
|
| dass |
TIGR00785 |
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally ... |
1-520 |
5.22e-54 |
|
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally characterized proteins of the DASS family transport (1) organic di- and tricarboxylates of the Krebs Cycle as well as dicarboxylate amino acid, (2) inorganic sulfate and (3) phosphate. The animal NaDC-1 cotransport 3 Na+ with each dicarboxylate. Protonated tricarboxylates are also cotransported with 3Na+. [Transport and binding proteins, Anions, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273267 [Multi-domain] Cd Length: 444 Bit Score: 189.09 E-value: 5.22e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 1 MAVYWCTEALPLSVTALLPI-VLFPFMGIL--PSNKVCPQYFLD-TNFLFLSGLIMASAIEEWNLHRRIALKILMLVGVQ 76
Cdd:TIGR00785 20 AIVGWILEPLPLPVTALLAIpIIAVLLGVLsaFKFKNALSGFADpTIWLFFGAFILATALVKTGLGKRIAYKLVGKMGGT 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 77 PARL-ILGMMVTTSFLSMWLSNTA-STAMMLPIANAILkslfgqkevrkdpsqeseentaavrrnglhtvptemqflast 154
Cdd:TIGR00785 100 TLGLgYFLVFLETLLAPMWPSNTArAGGILLPIIKSLL------------------------------------------ 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 155 eakdhpgetevpldlPADSRKEDEYRRNIWKGFLISIPYSASIGGTATLTGTAPNLILLGQLKSFFPQcdVVNFGSWFIF 234
Cdd:TIGR00785 138 ---------------PLLGSKPEKSPRKIGKYLMLGIAYSASIGSSGFLTGSAPNALAAGILSKILGI--QISWGDWFLA 200
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 235 AFPLMLLFLLAGWLWISFLYgglsfrgwrknKSEIRTNaeDRARAVIREEYQNLGPIKFAEQAVFILFcMFAILLFtrdp 314
Cdd:TIGR00785 201 GLPLGIILLLLVPLLLYVLF-----------PPELKLK--DEVDLWAKEELEEMGPMSFREKALLGIF-LLALLLW---- 262
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 315 kfipgwasLFNPGFLSDAVTGVAIVTILFFFPSqrpslkwwfdfkapntetepLLTWKKAQE-TVPWNIILLLGGGFAMA 393
Cdd:TIGR00785 263 --------IFGGSLGINASVVALLAVVLMLFLG--------------------IVTWKDIQKnKVAWNTLILFGGLIGLA 314
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 394 KGCEESGLSVWIGGQL-HPLENVPPALAVLLITVVIAFF-TEFASNTATIIIFLPVLAELAIRLRVHPLYLMIPGTVGCS 471
Cdd:TIGR00785 315 GGLKKSGFIKWFSEKLvGILDGLSPTIAVLVLVVLFYIIlYFFASNTAHTAALVPIFFSVASAQGIPLELLALALALSAS 394
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|
gi 58761541 472 FA-FMLPVSTPPNSIAFASGHLLVKDMVRTGLLMNLMGVLLLSLAMNTWA 520
Cdd:TIGR00785 395 LMgFLTPYATPPNAIAYGSGYVKIKDMWRVGAIIGIVGLIVLLLVGTLWW 444
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| CitT |
COG0471 |
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism]; |
47-519 |
4.34e-88 |
|
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism];
Pssm-ID: 440239 [Multi-domain] Cd Length: 369 Bit Score: 276.26 E-value: 4.34e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 47 LSGLIMASAIEEWNLHRRIALKILMLVGVQPARLILGMMVTTSFLSMWLSNTASTAMMLPIANAILKSLfgqkevrkdps 126
Cdd:COG0471 1 LGGFVLAAALEKTGLGRRIALLLLKRFGGSPLRLLLGLMLATALLSAFISNTARAAMMLPIALSIAAAL----------- 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 127 qeseentaavrrnglhtvptemqflasteakdhpgetevpldlpadsrkEDEYRRNIWKGFLISIPYSASIGGTATLTGT 206
Cdd:COG0471 70 -------------------------------------------------GSEKRSKFGSALLLPIAFAASIGGMGTLIGT 100
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 207 APNLILLGQLKSFFPQcdVVNFGSWFIFAFPLMLLFLLAGWLWISFLYgglsfrgwRKNKSEIrtnaeDRARAVIREEYQ 286
Cdd:COG0471 101 PPNLIAAGLLEEATGI--PISFFEWMLVGLPVALVGLLLLWLVLYRLL--------PPEIKEV-----PGSKEVIREELA 165
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 287 NLGPIKFAEQAVFILFCMFAILLFTRDPKFIPgwaslfnpgflsDAVTGVAIVTILFFFPsqrpslkwwfdfkapntete 366
Cdd:COG0471 166 ELGPLSRREKIALAIFALTVLLWITGSLHGIP------------IAVVALLGAVLLLLTG-------------------- 213
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 367 pLLTWKKAQETVPWNIILLLGGGFAMAKGCEESGLSVWIGGQL-HPLENVPPALAVLLITVVIAFFTEFASNTATIIIFL 445
Cdd:COG0471 214 -VLTWKDAYKSIPWGVLLLFGGGLALGAALEKTGLAAWLADALlPLLGGLSPLLLLLLLALLTLLLTEFASNTATAALLL 292
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 58761541 446 PVLAELAIRLRVHPLYLMIPGTVGCSFAFMLPVSTPPNSIAFASGHLLVKDMVRTGLLMNLMGVLLLSLAMNTW 519
Cdd:COG0471 293 PIAISLAQALGVNPLPLALAVAFAASCAFLLPVGTPPNAIVYGSGYYKFKDFLKVGLPLNLIGLVVLLLLGPLW 366
|
|
| SLC13_permease |
cd01115 |
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been ... |
1-511 |
1.91e-70 |
|
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is related to renal and intestinal Na+/sulfate cotransporters and a few putative bacterial permeases. The SLC13-type proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium and various anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease is composed of 8-13 transmembrane helices.
Pssm-ID: 238535 [Multi-domain] Cd Length: 382 Bit Score: 230.93 E-value: 1.91e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 1 MAVYWCTEALPLSVTALLPIVLFPFMGILPSNKVCPQYFLDTNFLFLSGLIMASAIEEWNLHRRIALKILMLVGVQPARL 80
Cdd:cd01115 7 AAVLFVTEALPLDVTALLVPVLLVLLGVVPPKEAFSGFSDPAVILFLAGFILGAALTRTGLAKRIATKLLKRAGKGERRL 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 81 ILGMMVTTSFLSMWLSNTASTAMMLPIANAILKSLfgqkevrkdpsqeseentaavrrnglhtvPTEMQFLasteakdhp 160
Cdd:cd01115 87 LLLLMLVTAFLSAFMSNTATVAIMLPVALGLAAKL-----------------------------DISPSRL--------- 128
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 161 getevpldlpadsrkedeyrrniwkgfLISIPYSASIGGTATLTGTAPNLILLGQLKSFFPQcdvvnfGSWFIFAFPLML 240
Cdd:cd01115 129 ---------------------------LMPLAFAASIGGMLTLIGTPPNLVASGYLESLGGQ------GFSFFEFTPIGL 175
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 241 LFLLAGWLWISFLYGglsfrgwrknkseirtnaedraravireeyqnlgpikfaeqavfILFCMFAILLFTrdpkfipgw 320
Cdd:cd01115 176 PLLIIGLLYLWFIFR--------------------------------------------LAVLIITIVLLA--------- 202
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 321 ASLFNPGFLSDAVTGVAIVTILFFFPsqrpslkwwfdfkapntetepLLTWKKAQETVPWNIILLLGGGFAMAKGCEESG 400
Cdd:cd01115 203 ALAAITGLLPVSVAIAIGAIVLVFGG---------------------VLLTKEDYKSIDWGIIFLFAGGIPLGKALESSG 261
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 401 LSVWIGGQLHP-LENVPPALAVLLITVVIAFFTEFASNTATIIIFLPVLAELAIRLRVHPLYLMIPGTVGCSFAFMLPVS 479
Cdd:cd01115 262 AAALIAEALISlLGGLPPFAILLLLCLLTLVLTNFISNTATAVLLAPIALSIALSLGLPPEALLLAVAIGASCAFMLPVG 341
|
490 500 510
....*....|....*....|....*....|..
gi 58761541 480 TPPNSIAFASGHLLVKDMVRTGLLMNLMGVLL 511
Cdd:cd01115 342 TPPNAIVLGPGGYKFSDFAKVGLPLSILSLVV 373
|
|
| Na_sulph_symp |
pfam00939 |
Sodium:sulfate symporter transmembrane region; There are also some members in this family that ... |
1-519 |
3.06e-62 |
|
Sodium:sulfate symporter transmembrane region; There are also some members in this family that do not match the Prosite motif, and belong to the subfamily SODIT1.
Pssm-ID: 279307 [Multi-domain] Cd Length: 472 Bit Score: 211.85 E-value: 3.06e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 1 MAVYWCTEALPLSVTALLPIVLFPFMGILPSNKVCPQ----YFLDTNFLFLSGLIMASAIEEWNLHRRIALKILMLVGVQ 76
Cdd:pfam00939 40 TIVGWILEPLPMAVIALFAISLSAILIGTLLAKALSWalsgFSSTTTWLVFGAFFISAAFEKTGLGRRIALVLVKKMGKR 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 77 ParLILGMMVTTSFLSMWLSNTASTAMMLPIANAILKSL---FGqkevrkdpsqeseentaavrrnglhtvptemqflas 153
Cdd:pfam00939 120 T--LGLGYGLVFSDLLLAPATPSNTARAGGIVFPIIMSLppaFG------------------------------------ 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 154 teakdhpgetevpldlpadSRKEDEYRRNIWKGFLISIPYSASIGGTATLTGTAPNLILLGQLKSFFPQcdVVNFGSWFI 233
Cdd:pfam00939 162 -------------------SDPEKGSERRIGAYLMWTVYQSTSITSAMFLTAMAPNLLLLGLMNSILGV--TITWASWFL 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 234 FAFPLMLLFLLAGWLWISFLYGGLSFRGwrknkseirtnaeDRARAVIREEYQNLGPIKFAEQAVFILFCMFAILLFTRD 313
Cdd:pfam00939 221 AAIPPGVILLLLAPLLLYVLYPPEIKSV-------------PDAKAIAKTELKELGPMTFREKALLGLFVLLLLLWIFGG 287
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 314 PKFIpgwaslfnpgflSDAVTGVAIVTILFFFPsqrpslkwwfdfkapntetepLLTWKKA-QETVPWNIILLLGGGFAM 392
Cdd:pfam00939 288 SLNI------------DATTVAIIGLALMLLLR---------------------ILDWKDIvKNKGAWNTLIWLGGLIML 334
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 393 AKGCEESGLSVWIGGQLHPL--ENVPPALAVLLITVVIAFFTEFASNTATIIIFLPVLAELAIRLRVHP-LYLMIPGTVG 469
Cdd:pfam00939 335 ANGLERSGFIEWLGNTLSTSlsGFSPAMAFIIILSLFYLSHYLFASATAHTAAMLPIFAAVAQAIPGAPpLLAALLLGFA 414
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|.
gi 58761541 470 CSFA-FMLPVSTPPNSIAFASGHLLVKDMVRTGLLMNLMGVLLLSLAMNTW 519
Cdd:pfam00939 415 ISLGgFLTPYGTGPGPIYFGSGYLKVKDWWRIGAILTIIGLLILLLLGNWW 465
|
|
| dass |
TIGR00785 |
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally ... |
1-520 |
5.22e-54 |
|
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally characterized proteins of the DASS family transport (1) organic di- and tricarboxylates of the Krebs Cycle as well as dicarboxylate amino acid, (2) inorganic sulfate and (3) phosphate. The animal NaDC-1 cotransport 3 Na+ with each dicarboxylate. Protonated tricarboxylates are also cotransported with 3Na+. [Transport and binding proteins, Anions, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273267 [Multi-domain] Cd Length: 444 Bit Score: 189.09 E-value: 5.22e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 1 MAVYWCTEALPLSVTALLPI-VLFPFMGIL--PSNKVCPQYFLD-TNFLFLSGLIMASAIEEWNLHRRIALKILMLVGVQ 76
Cdd:TIGR00785 20 AIVGWILEPLPLPVTALLAIpIIAVLLGVLsaFKFKNALSGFADpTIWLFFGAFILATALVKTGLGKRIAYKLVGKMGGT 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 77 PARL-ILGMMVTTSFLSMWLSNTA-STAMMLPIANAILkslfgqkevrkdpsqeseentaavrrnglhtvptemqflast 154
Cdd:TIGR00785 100 TLGLgYFLVFLETLLAPMWPSNTArAGGILLPIIKSLL------------------------------------------ 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 155 eakdhpgetevpldlPADSRKEDEYRRNIWKGFLISIPYSASIGGTATLTGTAPNLILLGQLKSFFPQcdVVNFGSWFIF 234
Cdd:TIGR00785 138 ---------------PLLGSKPEKSPRKIGKYLMLGIAYSASIGSSGFLTGSAPNALAAGILSKILGI--QISWGDWFLA 200
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 235 AFPLMLLFLLAGWLWISFLYgglsfrgwrknKSEIRTNaeDRARAVIREEYQNLGPIKFAEQAVFILFcMFAILLFtrdp 314
Cdd:TIGR00785 201 GLPLGIILLLLVPLLLYVLF-----------PPELKLK--DEVDLWAKEELEEMGPMSFREKALLGIF-LLALLLW---- 262
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 315 kfipgwasLFNPGFLSDAVTGVAIVTILFFFPSqrpslkwwfdfkapntetepLLTWKKAQE-TVPWNIILLLGGGFAMA 393
Cdd:TIGR00785 263 --------IFGGSLGINASVVALLAVVLMLFLG--------------------IVTWKDIQKnKVAWNTLILFGGLIGLA 314
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 394 KGCEESGLSVWIGGQL-HPLENVPPALAVLLITVVIAFF-TEFASNTATIIIFLPVLAELAIRLRVHPLYLMIPGTVGCS 471
Cdd:TIGR00785 315 GGLKKSGFIKWFSEKLvGILDGLSPTIAVLVLVVLFYIIlYFFASNTAHTAALVPIFFSVASAQGIPLELLALALALSAS 394
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|
gi 58761541 472 FA-FMLPVSTPPNSIAFASGHLLVKDMVRTGLLMNLMGVLLLSLAMNTWA 520
Cdd:TIGR00785 395 LMgFLTPYATPPNAIAYGSGYVKIKDMWRVGAIIGIVGLIVLLLVGTLWW 444
|
|
| ArsB_NhaD_permease |
cd00625 |
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, ... |
2-516 |
3.57e-42 |
|
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump.
Pssm-ID: 238344 [Multi-domain] Cd Length: 396 Bit Score: 155.87 E-value: 3.57e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 2 AVYWCTEALPLSVTALLPIVLFPFMGILPSNKVCPQYFLDTNFLFLSGLIMASAIEEWNLHRRIALKIlMLVGVQPARLI 81
Cdd:cd00625 1 YVLIRPEKLPRAVVALLGAVLLVLLGVVSPKEALSAIDWETILLLFGMMILSAALEETGLFDRLAAKL-ARASKGSRRLL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 82 LGMMVTTSFLSMWLSNTASTAMMLPIANAILKslfgqkevrkdpsqeseentaavRRNGLHTVPtemqflasteakdhpg 161
Cdd:cd00625 80 LLLMLLTAALSAFFSNDATAVLLTPIVLALLR-----------------------KLGLSPPVP---------------- 120
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 162 etevpldlpadsrkedeyrrniwkgFLISIPYSASIGGTATLTGTAPNLILLGQLKsffpqcdvVNFGSWFIFAFPLMLL 241
Cdd:cd00625 121 -------------------------LLLALAFAANIGGAATPIGNPPNLIIASLSG--------LGFLDFLAFMAPPALG 167
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 242 FLLAGWLWISFLYGGlsfrgwrknksEIRTNAEDRARAVIREEYQNLGPIKFAEQAVFILFCMFAILLFTRDPKFIpgwa 321
Cdd:cd00625 168 LLLLLLGLLYLLFRK-----------KLLLPDEDKLTVLAEPLPARPLLKKFLLLALLLLLLFVLLFFFLIPLGLI---- 232
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 322 slfnpgflsdAVTGVAIVTILFFFpsqrpslkwwfdfkapntetepLLTWKKAQETVPWNIILLLGGGFAMAKGCEESGL 401
Cdd:cd00625 233 ----------ALLGALLLLLLLVR----------------------GLDPEEVLKSVDWGTLLFFAGLFVLVGALESTGL 280
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 402 SVWIGGQLHPLENVPPALAVLLITVVIAFFTEFASNTATIIIFLPVLAEL-----AIRLRVHPLYLMIPGTVGCSFAFML 476
Cdd:cd00625 281 LEWLAELLVALVGLPPLAALLLIGLLSALLSNFISNVPTVALLLPIAASLappepAWLALALGSTLGGNLTLIGSLANLI 360
|
490 500 510 520
....*....|....*....|....*....|....*....|
gi 58761541 477 PVSTPPNSIAfasgHLLVKDMVRTGLLMNLMgVLLLSLAM 516
Cdd:cd00625 361 PLGAAENAGV----GISFGEFLKVGLPLTLL-SLVVSLLY 395
|
|
| CitMHS |
pfam03600 |
Citrate transporter; |
2-452 |
1.09e-31 |
|
Citrate transporter;
Pssm-ID: 460985 [Multi-domain] Cd Length: 342 Bit Score: 125.50 E-value: 1.09e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 2 AVYWCTEALPLSVTALLPIVLFPFMGILPSNKVCPQYFLDTNFLFLSGLIMASAIEEWNLHRRIALKILMLVGVQPARLI 81
Cdd:pfam03600 1 YVLIITEKLPRDVVALLGAVLLVLLGVLTPEEALSGIDSPTILLLLGMMIIGAILERTGLFDRLALKLLRLAGGKPRRLL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 82 LGMMVTTSFLSMWLSNTASTAMMLPIANAIlkslfgqkevrkdpsqeseentaaVRRNGLHTVPtemqflasteakdhpg 161
Cdd:pfam03600 81 VALMLATALLSAFLSNDGTVLIMIPIVLAL------------------------ARRLGLPPSP---------------- 120
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 162 etevpldlpadsrkedeyrrniwkgFLISIPYSASIGGTATLTGTAPNLILLGQLKsffpqcdvVNFGSWFIFAFPLMLL 241
Cdd:pfam03600 121 -------------------------LLIALAFAANIGGTATPIGDPPNIIIASALG--------LSFGDFGFFMFPPVGV 167
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 242 FLLAGWLWISFLYGGLSFRGWRKNKSEIRTNAEDRARAVIreeyqnlgpikfaeqAVFILFCMFAILLFtrdpkfipgwa 321
Cdd:pfam03600 168 ALLLVGLLPLLLIFRKLLPVRKEEEAELEELRKRAIKDKL---------------LLAISALVLALVIL----------- 221
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 322 slfnpGFLSDAVTGVAIVTILFFFPSqrpslkwwfdfkapnteteplLTWKKAQETVPWNIILLLGGGFAMAKGCEESGL 401
Cdd:pfam03600 222 -----GFLLLSVLALAGALLLLLTGV---------------------LDPEEALKAVDWSTLLFFAGLFILVGALEKTGL 275
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|.
gi 58761541 402 SVWIGGQLHPLenVPPALAVLLITVVIAFFTEFASNTATIIIFLPVLAELA 452
Cdd:pfam03600 276 ADALADALGGL--SGLLVALALILWLSALLSAFISNVPTAALMAPIIVGMA 324
|
|
| ArsB |
COG1055 |
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism]; |
10-464 |
2.54e-11 |
|
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism];
Pssm-ID: 440675 [Multi-domain] Cd Length: 415 Bit Score: 65.53 E-value: 2.54e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 10 LPLSVTALLPIVLFPFMGILPSNKVCPQYFLDTNFLFLSGLIMASAIEEWNLHRRIALKILMLVGVQPARLILGMMVTTS 89
Cdd:COG1055 23 LNRAVAALLGAALLLLLGVVSLEDALEAIDWNTILFLLGMMIIVAILDESGFFEWLAIKLARRAKGSPRRLLWLLGLLTA 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 90 FLSMWLSNTASTAMMLPIANAIlkslfgqkevrkdpsqeseentaaVRRNGLHTVPtemqflasteakdhpgetevpldl 169
Cdd:COG1055 103 LLSAFLDNDTTALLLTPVVLAI------------------------ARRLGLNPVP------------------------ 134
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 170 padsrkedeyrrniwkgFLISIPYSASIGGTATLTGTAPNLILLGQLKsffpqcdvVNFGSWFIFAFPLMLLFLLAGWLW 249
Cdd:COG1055 135 -----------------FLIAIVFAANIGGAATPIGNPTNIMIASAGG--------LSFLDFLANLFPPSLVSLLVTLLV 189
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 250 ISFLYGGlSFRGWRKNKSEIRTNAEDRARAVIreeyqnlgpikfaeqAVFILFCMFAILLFTRDPKFIPGWASLFnpgfl 329
Cdd:COG1055 190 LYLLFRK-ELPAAPDLEDDPKEAIKDRRLLRI---------------SLLVLALLLVGFVLHSFLGLPPALIALL----- 248
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 330 sdavtgVAIVTILFffpsqrpslkwwfdfkapnTETEPLLTWKKaqetVPWNIILLLGGGFAMAKGCEESGLSVWIGGQL 409
Cdd:COG1055 249 ------GAAVLLLL-------------------ARVDVREVLKK----VDWSTLLFFIGLFVVVGGLENTGLLDLLAELL 299
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*
gi 58761541 410 HPLENVPPALAVLLITVVIAFFTEFASNTATIIIFLPVLAELAIRLRVHPLYLMI 464
Cdd:COG1055 300 ASLTGGNLLLAALLILWLSAILSAVVDNVPLVAALLPLIPDLGATGNPEPLWLAL 354
|
|
| CitMHS |
pfam03600 |
Citrate transporter; |
367-516 |
2.61e-10 |
|
Citrate transporter;
Pssm-ID: 460985 [Multi-domain] Cd Length: 342 Bit Score: 61.94 E-value: 2.61e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 367 PLLTWKKAQETVPWNIILLLGGGFAMAKGCEESGLSVWIGGQLHPLENVPPALAVLLITVVIAFFTEFASNTATIIIFLP 446
Cdd:pfam03600 26 GVLTPEEALSGIDSPTILLLLGMMIIGAILERTGLFDRLALKLLRLAGGKPRRLLVALMLATALLSAFLSNDGTVLIMIP 105
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 58761541 447 VLAELAIRLRVHPLYLMIPGTVGCSFAFML-PVSTPPNSIAFASGHLLVKDMVRTGLLMNLMGVLLLSLAM 516
Cdd:pfam03600 106 IVLALARRLGLPPSPLLIALAFAANIGGTAtPIGDPPNIIIASALGLSFGDFGFFMFPPVGVALLLVGLLP 176
|
|
| ArsB |
COG1055 |
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism]; |
368-492 |
4.60e-08 |
|
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism];
Pssm-ID: 440675 [Multi-domain] Cd Length: 415 Bit Score: 55.52 E-value: 4.60e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 368 LLTWKKAQETVPWNIILLLGGGFAMAKGCEESGLSVWIGGQLHPLENVPPALAVLLITVVIAFFTEFASNTATIIIFLPV 447
Cdd:COG1055 41 VVSLEDALEAIDWNTILFLLGMMIIVAILDESGFFEWLAIKLARRAKGSPRRLLWLLGLLTALLSAFLDNDTTALLLTPV 120
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 58761541 448 LAELAIRLRVHPLYLMIpgtvGCSFA-----FMLPVSTPPNSIAFASGHL 492
Cdd:COG1055 121 VLAIARRLGLNPVPFLI----AIVFAaniggAATPIGNPTNIMIASAGGL 166
|
|
| P_permease |
cd01116 |
Permease P (pink-eyed dilution). Mutations in the human melanosomal P gene were responsible ... |
37-473 |
8.40e-08 |
|
Permease P (pink-eyed dilution). Mutations in the human melanosomal P gene were responsible for classic phenotype of oculocutaneous albinism type 2 (OCA2). Although the precise function of the P protein is unknown, it was predicted to regulate the intraorganelle pH, together with the ATP-driven proton pump. It shows significant sequence similarity to the Na+/H+ antiporter NhaD from Vibrio parahaemolyticus. Both proteins belong to ArsB/NhaD superfamily of permeases that translocate sodium, arsenate, sulfate, and organic anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease contains 8-13 transmembrane domains.
Pssm-ID: 238536 [Multi-domain] Cd Length: 413 Bit Score: 54.57 E-value: 8.40e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 37 QYFLDTNFLFLSGLIMASAIEEWNLHRRIALKILMLVGVQPARLILGMMVTTSFLSMWLSNTASTAMMLPIANAIlkslf 116
Cdd:cd01116 44 WVDWETLALLLGMMIIVSILSETGVFEYLAIWAVKISKGRPWRLLLLLGLLTAFLSAFLDNVTTVLLMVPVTIRL----- 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 117 gqkevrkdpsqeseentaaVRRNGLHTVPtemqflasteakdhpgetevpldlpadsrkedeyrrniwkgFLISIPYSAS 196
Cdd:cd01116 119 -------------------CEVLGLNPVP-----------------------------------------VLISEVIAAN 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 197 IGGTATLTGTAPNLILlgqlksffPQCDVVNFGSWFIFAFPLMLLFLLAGWLWISFLYGglsfRGWRKNKSEIRTNAEDR 276
Cdd:cd01116 139 IGGAATLIGDPPNIMI--------GSAAGLTFNDFLLHMLPSVVLALVVTFILLYFLYR----NILKAREEDVLALAELE 206
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 277 ARAVIREeyqnlgpIKFAEQAVFILFCMFAILLFTRDPKFIPGWaslfnpgflsdaVTGVAIVTILFFFPsqrpslkwwf 356
Cdd:cd01116 207 PKYPIKD-------KVLLLKSLTILTLVIIGFVLHSPLGVSLGW------------IALLGALLLLLLAD---------- 257
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 357 dfkapntetepLLTWKKAQETVPWNIILLLGGGFAMAKGCEESGLSVWIGGQLHPLENVPPALAVLLITVVIAFFTEFAS 436
Cdd:cd01116 258 -----------KLDFEDVLSRVEWDTLLFFAGLFVLVGGLEELGIIEWIAELLVGVILGRIAVAVILILWISALLSAFID 326
|
410 420 430
....*....|....*....|....*....|....*..
gi 58761541 437 NTATIIIFLPVLAELAIRLRVHPLYLMIPGTVGCSFA 473
Cdd:cd01116 327 NIPVTATMIPIVKDLASQLGIPLLPLWWALALGACLG 363
|
|
| CitT |
COG0471 |
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism]; |
1-115 |
7.10e-06 |
|
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism];
Pssm-ID: 440239 [Multi-domain] Cd Length: 369 Bit Score: 48.23 E-value: 7.10e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 1 MAVYWCTEA---LPLSVTALLPIVLFPFMGILPSNKVcpQYFLDTNFLFL--SGLIMASAIEEWNLHRRIALKIL-MLVG 74
Cdd:COG0471 184 TVLLWITGSlhgIPIAVVALLGAVLLLLTGVLTWKDA--YKSIPWGVLLLfgGGLALGAALEKTGLAAWLADALLpLLGG 261
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 58761541 75 VQPARLILGMMVTTSFLSMWLSNTASTAMMLPIANAILKSL 115
Cdd:COG0471 262 LSPLLLLLLLALLTLLLTEFASNTATAALLLPIAISLAQAL 302
|
|
| ArsB |
COG1055 |
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism]; |
193-254 |
1.96e-04 |
|
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism];
Pssm-ID: 440675 [Multi-domain] Cd Length: 415 Bit Score: 43.96 E-value: 1.96e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 58761541 193 YSASIGGTATLTGTAPNLILLGQLKSffpQCDVVNFGSWFIFAFPLMLLFLLAGWLWISFLY 254
Cdd:COG1055 356 LGATLGGNLTPIGSAANVIVLGIAEK---KGIKISFGEFLKVGLPLTLLTLLIALLYLLLLY 414
|
|
| ArsB_permease |
cd01118 |
Anion permease ArsB. These permeases have been shown to export arsenate and antimonite in ... |
380-492 |
2.26e-03 |
|
Anion permease ArsB. These permeases have been shown to export arsenate and antimonite in eubacteria and archaea. A typical ArsB permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump (ArsAB). The ArsAB complex is similar in many ways to ATP-binding cassette transporters, which have two groups of six transmembrane-spanning helical segments and two nucleotide-binding domains. The ArsB proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium, arsenate, sulfate, and organic anions across biological membranes in all three kingdoms of life.
Pssm-ID: 238538 [Multi-domain] Cd Length: 416 Bit Score: 40.71 E-value: 2.26e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58761541 380 WNIILLLGGGFAMAKGCEESGLSVWIGGQLHPLENVPPALAVLLITVVIAFFTEFASNTATIIIFLPVLAELAIRLRVHP 459
Cdd:cd01118 52 WDVTLTLIGVILLSLLLDEEGFFEWVAALAARWARGSGRKLFTLIVLLGAAVTAFFANDGTALILTPIVIALLRALGAKK 131
|
90 100 110
....*....|....*....|....*....|....*..
gi 58761541 460 L----YLMIPGTVGCSFAFMLPVSTPPNSIAFASGHL 492
Cdd:cd01118 132 NrtlpFLYACAFIADAASLPLPISNLVNIVTAGYFGI 168
|
|
| |
