NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|67972425|ref|NP_001019790|]
View 

tsukushi precursor [Mus musculus]

Protein Classification

leucine-rich repeat domain-containing protein( domain architecture ID 11469232)

leucine-rich repeat (LRR) domain-containing protein may participate in protein-protein interactions

CATH:  3.80.10.10
Gene Ontology:  GO:0005515
PubMed:  11751054|7583641

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
85-300 1.57e-18

Leucine-rich repeat (LRR) protein [Transcription];


:

Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 86.14  E-value: 1.57e-18
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67972425  85 TTLAGLDLSYNLLTSImPSAFSRLRYLESLDLSHNGLAALPAEIFTSSPLSDINLSHNRLREVSISAftthSQGRAL-HV 163
Cdd:COG4886 113 TNLESLDLSGNQLTDL-PEELANLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLTDLPEEL----GNLTNLkEL 187

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67972425 164 DLSHNLIhrllphparASLPAP-----TIQSLNLSWNRFRAVPD-LRDLP-LRYLSLDGNPLATInpDAFMGLAGLTHLS 236
Cdd:COG4886 188 DLSNNQI---------TDLPEPlgnltNLEELDLSGNQLTDLPEpLANLTnLETLDLSNNQLTDL--PELGNLTNLEELD 256

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 67972425 237 LASLQgILHLPPHGfrELPGLQVLDLSGNP--KLKWAGAEVFSGLGLLQELDLSGSSLVPLPEMLL 300
Cdd:COG4886 257 LSNNQ-LTDLPPLA--NLTNLKTLDLSNNQltDLKLKELELLLGLNSLLLLLLLLNLLELLILLLL 319
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
85-300 1.57e-18

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 86.14  E-value: 1.57e-18
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67972425  85 TTLAGLDLSYNLLTSImPSAFSRLRYLESLDLSHNGLAALPAEIFTSSPLSDINLSHNRLREVSISAftthSQGRAL-HV 163
Cdd:COG4886 113 TNLESLDLSGNQLTDL-PEELANLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLTDLPEEL----GNLTNLkEL 187

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67972425 164 DLSHNLIhrllphparASLPAP-----TIQSLNLSWNRFRAVPD-LRDLP-LRYLSLDGNPLATInpDAFMGLAGLTHLS 236
Cdd:COG4886 188 DLSNNQI---------TDLPEPlgnltNLEELDLSGNQLTDLPEpLANLTnLETLDLSNNQLTDL--PELGNLTNLEELD 256

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 67972425 237 LASLQgILHLPPHGfrELPGLQVLDLSGNP--KLKWAGAEVFSGLGLLQELDLSGSSLVPLPEMLL 300
Cdd:COG4886 257 LSNNQ-LTDLPPLA--NLTNLKTLDLSNNQltDLKLKELELLLGLNSLLLLLLLLNLLELLILLLL 319
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 64-175 5.65e-09

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 57.55  E-value: 5.65e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67972425   64 LDLSSNRLETVNESVLAGpgYTTLAGLDLSYNLLTSIMPSAFSRLRYLESLDLSHNGLAALPAEIFTSSP-LSDINLSHN 142
Cdd:PLN00113 480 LDLSRNQFSGAVPRKLGS--LSELMQLKLSENKLSGEIPDELSSCKKLVSLDLSHNQLSGQIPASFSEMPvLSQLDLSQN 557

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 67972425  143 RLrevsiSAFTTHSQGRA---LHVDLSHNLIHRLLP 175
Cdd:PLN00113 558 QL-----SGEIPKNLGNVeslVQVNISHNHLHGSLP 588
LRR_8 pfam13855
Leucine rich repeat;
208-266 5.81e-09

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 51.76  E-value: 5.81e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 67972425   208 LRYLSLDGNPLATINPDAFMGLAGLTHLSLASLQgILHLPPHGFRELPGLQVLDLSGNP 266
Cdd:pfam13855   3 LRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNL-LTTLSPGAFSGLPSLRYLDLSGNR 60
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 60-275 7.06e-04

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 41.19  E-value: 7.06e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67972425  60 DTAHLDLSSNRLETVNESV-LAGPGYTTLAGL---DLSYNLLTSIMPSAFSRLR---YLESLDLSHNGLAALPAEIFT-- 130
Cdd:cd00116  52 SLKELCLSLNETGRIPRGLqSLLQGLTKGCGLqelDLSDNALGPDGCGVLESLLrssSLQELKLNNNGLGDRGLRLLAkg 131

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67972425 131 ----SSPLSDINLSHNRL-REVSISAFTTHSQGRALH-VDLSHNLI-HRLLPHPARASLPAPTIQSLNLSWNRFR----- 198
Cdd:cd00116 132 lkdlPPALEKLVLGRNRLeGASCEALAKALRANRDLKeLNLANNGIgDAGIRALAEGLKANCNLEVLDLNNNGLTdegas 211

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67972425 199 ----AVPDLRDLplRYLSLDGNPL-----ATINPDAFMGLAGLTHLSLASLqgilHLPPHGFREL-------PGLQVLDL 262
Cdd:cd00116 212 alaeTLASLKSL--EVLNLGDNNLtdagaAALASALLSPNISLLTLSLSCN----DITDDGAKDLaevlaekESLLELDL 285

                       250
                ....*....|...
gi 67972425 263 SGNpKLKWAGAEV 275
Cdd:cd00116 286 RGN-KFGEEGAQL 297
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
85-300 1.57e-18

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 86.14  E-value: 1.57e-18
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67972425  85 TTLAGLDLSYNLLTSImPSAFSRLRYLESLDLSHNGLAALPAEIFTSSPLSDINLSHNRLREVSISAftthSQGRAL-HV 163
Cdd:COG4886 113 TNLESLDLSGNQLTDL-PEELANLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLTDLPEEL----GNLTNLkEL 187

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67972425 164 DLSHNLIhrllphparASLPAP-----TIQSLNLSWNRFRAVPD-LRDLP-LRYLSLDGNPLATInpDAFMGLAGLTHLS 236
Cdd:COG4886 188 DLSNNQI---------TDLPEPlgnltNLEELDLSGNQLTDLPEpLANLTnLETLDLSNNQLTDL--PELGNLTNLEELD 256

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 67972425 237 LASLQgILHLPPHGfrELPGLQVLDLSGNP--KLKWAGAEVFSGLGLLQELDLSGSSLVPLPEMLL 300
Cdd:COG4886 257 LSNNQ-LTDLPPLA--NLTNLKTLDLSNNQltDLKLKELELLLGLNSLLLLLLLLNLLELLILLLL 319
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
34-311 1.69e-15

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 76.90  E-value: 1.69e-15
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67972425  34 LFDSFSLIRVDCSSLGPHIVPVPIPLDTAHLDLSSNRLETVNESVLAGPGYTTLAGLDLSYNLLTSIMPSAFSRLRYLES 113
Cdd:COG4886  21 LTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTE 100

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67972425 114 LDLSHNglaalpAEIFTSSPLSDINLSHNRLRE--VSISAFTthsqgrAL-HVDLSHNLIHRLlpHPARASLPAptIQSL 190
Cdd:COG4886 101 LDLSGN------EELSNLTNLESLDLSGNQLTDlpEELANLT------NLkELDLSNNQLTDL--PEPLGNLTN--LKSL 164

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67972425 191 NLSWNRFRAVPD-LRDLP-LRYLSLDGNPLATInPDAFMGLAGLTHLSLASLQgILHLPPhGFRELPGLQVLDLSGNP-- 266
Cdd:COG4886 165 DLSNNQLTDLPEeLGNLTnLKELDLSNNQITDL-PEPLGNLTNLEELDLSGNQ-LTDLPE-PLANLTNLETLDLSNNQlt 241

                       250       260       270       280
                ....*....|....*....|....*....|....*....|....*
gi 67972425 267 KLKWagaevFSGLGLLQELDLSGSSLVPLPEmlLHHLPALQSVSV 311
Cdd:COG4886 242 DLPE-----LGNLTNLEELDLSNNQLTDLPP--LANLTNLKTLDL 279
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
63-268 8.79e-11

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 62.64  E-value: 8.79e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67972425  63 HLDLSSNRLETVNESvLAGPgyTTLAGLDLSYNLLTSImPSAFSRLRYLESLDLSHNGLAALPaEIFTSSPLSDINLSHN 142
Cdd:COG4886 186 ELDLSNNQITDLPEP-LGNL--TNLEELDLSGNQLTDL-PEPLANLTNLETLDLSNNQLTDLP-ELGNLTNLEELDLSNN 260

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67972425 143 RLREVSISAFTTHSQgralHVDLSHNLIHRL-LPHPARASLPAPTIQSLNLSWNRFRAVPDLRDLPLRYLSLDGNPLATI 221
Cdd:COG4886 261 QLTDLPPLANLTNLK----TLDLSNNQLTDLkLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVT 336

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*..
gi 67972425 222 NPDAFMGLAGLTHLSLASLQGILHLPPHGFRELPGLQVLDLSGNPKL 268
Cdd:COG4886 337 LTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLA 383
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 64-175 5.65e-09

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 57.55  E-value: 5.65e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67972425   64 LDLSSNRLETVNESVLAGpgYTTLAGLDLSYNLLTSIMPSAFSRLRYLESLDLSHNGLAALPAEIFTSSP-LSDINLSHN 142
Cdd:PLN00113 480 LDLSRNQFSGAVPRKLGS--LSELMQLKLSENKLSGEIPDELSSCKKLVSLDLSHNQLSGQIPASFSEMPvLSQLDLSQN 557

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 67972425  143 RLrevsiSAFTTHSQGRA---LHVDLSHNLIHRLLP 175
Cdd:PLN00113 558 QL-----SGEIPKNLGNVeslVQVNISHNHLHGSLP 588
LRR_8 pfam13855
Leucine rich repeat;
208-266 5.81e-09

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 51.76  E-value: 5.81e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 67972425   208 LRYLSLDGNPLATINPDAFMGLAGLTHLSLASLQgILHLPPHGFRELPGLQVLDLSGNP 266
Cdd:pfam13855   3 LRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNL-LTTLSPGAFSGLPSLRYLDLSGNR 60
LRR_8 pfam13855
Leucine rich repeat;
64-121 6.01e-08

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 49.06  E-value: 6.01e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 67972425    64 LDLSSNRLETVNESVLAGPgyTTLAGLDLSYNLLTSIMPSAFSRLRYLESLDLSHNGL 121
Cdd:pfam13855   6 LDLSNNRLTSLDDGAFKGL--SNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 64-265 1.70e-06

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 49.85  E-value: 1.70e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67972425   64 LDLSSNRLETVNESVLAGPGYttLAGLDLSYNLLTSIMPSAFSRLRYLESLDLSHNGLAA-LPAEiFTSSPLSD-INLSH 141
Cdd:PLN00113 361 LDLSTNNLTGEIPEGLCSSGN--LFKLILFSNSLEGEIPKSLGACRSLRRVRLQDNSFSGeLPSE-FTKLPLVYfLDISN 437

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67972425  142 NRLREVSISAFTTHSQGRALhvDLSHNLIHRLLPHPARASlpapTIQSLNLSWNRFR-AVPD-LRDLP-LRYLSLDGNPL 218
Cdd:PLN00113 438 NNLQGRINSRKWDMPSLQML--SLARNKFFGGLPDSFGSK----RLENLDLSRNQFSgAVPRkLGSLSeLMQLKLSENKL 511

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 67972425  219 ATINPDAFMGLAGLTHLSLASLQGILHLPPhGFRELPGLQVLDLSGN 265
Cdd:PLN00113 512 SGEIPDELSSCKKLVSLDLSHNQLSGQIPA-SFSEMPVLSQLDLSQN 557
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
48-266 2.62e-06

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 49.31  E-value: 2.62e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67972425   48 LGPHIVPVPIPLDTAHLDLSSNRLET-------------VNESVLAGPGYT---TLAGLDLSYNLLTSI---MPSAfsrl 108
Cdd:PRK15370 188 LGLTTIPACIPEQITTLILDNNELKSlpenlqgniktlyANSNQLTSIPATlpdTIQEMELSINRITELperLPSA---- 263

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67972425  109 ryLESLDLSHNGLAALPAEIftSSPLSDINLSHNrlrevSISAFTTHSQGRALHVDLSHNLIHRL---LP---------H 176
Cdd:PRK15370 264 --LQSLDLFHNKISCLPENL--PEELRYLSVYDN-----SIRTLPAHLPSGITHLNVQSNSLTALpetLPpglktleagE 334

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67972425  177 PARASLPA---PTIQSLNLSWNRFRAVPDLRDLPLRYLSLDGNPLATInPDAFMglAGLTHLSlASLQGILHLP---PHG 250
Cdd:PRK15370 335 NALTSLPAslpPELQVLDVSKNQITVLPETLPPTITTLDVSRNALTNL-PENLP--AALQIMQ-ASRNNLVRLPeslPHF 410

                        250
                 ....*....|....*.
gi 67972425  251 FRELPGLQVLDLSGNP 266
Cdd:PRK15370 411 RGEGPQPTRIIVEYNP 426
LRR_8 pfam13855
Leucine rich repeat;
231-292 7.42e-06

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 42.90  E-value: 7.42e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 67972425   231 GLTHLSLASlQGILHLPPHGFRELPGLQVLDLSGNpKLKWAGAEVFSGLGLLQELDLSGSSL 292
Cdd:pfam13855   2 NLRSLDLSN-NRLTSLDDGAFKGLSNLKVLDLSNN-LLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRR_8 pfam13855
Leucine rich repeat;
185-239 9.97e-06

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 42.51  E-value: 9.97e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 67972425   185 PTIQSLNLSWNRFRAVPD--LRDLP-LRYLSLDGNPLATINPDAFMGLAGLTHLSLAS 239
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDgaFKGLSnLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSG 58
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
113-338 1.01e-05

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 47.38  E-value: 1.01e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67972425  113 SLDLSHNGLAALPAEIftSSPLSDINLSHNRLREVSISAFTTHSQgralhVDLSHNLIHRLLPHparasLPApTIQSLNL 192
Cdd:PRK15370 203 TLILDNNELKSLPENL--QGNIKTLYANSNQLTSIPATLPDTIQE-----MELSINRITELPER-----LPS-ALQSLDL 269

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67972425  193 SWNRFRAVPDlrDLP--LRYLSLDGNPLATInPDAFMglAGLTHLSLASlQGILHLP---PHGFREL------------- 254
Cdd:PRK15370 270 FHNKISCLPE--NLPeeLRYLSVYDNSIRTL-PAHLP--SGITHLNVQS-NSLTALPetlPPGLKTLeagenaltslpas 343

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67972425  255 --PGLQVLDLSGN-----PKlkwagaevfSGLGLLQELDLSGSSLVPLPEmllhHLPALQSVSVGQDVQCRRLVREGAYH 327
Cdd:PRK15370 344 lpPELQVLDVSKNqitvlPE---------TLPPTITTLDVSRNALTNLPE----NLPAALQIMQASRNNLVRLPESLPHF 410

                        250
                 ....*....|.
gi 67972425  328 RQPGSSPKVVL 338
Cdd:PRK15370 411 RGEGPQPTRII 421
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 64-299 1.52e-04

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 43.68  E-value: 1.52e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67972425   64 LDLSSNRL--ETVNESVLagpgYTTLAGLDLSYNLLTSIMPSAFSRLRYLESLDLSHNGLAA-LPAEIFTSSPLSDINLS 140
Cdd:PLN00113 145 LDLSNNMLsgEIPNDIGS----FSSLKVLDLGGNVLVGKIPNSLTNLTSLEFLTLASNQLVGqIPRELGQMKSLKWIYLG 220

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67972425  141 HNRLR---EVSISAFTTHSqgralHVDLSHNlihrllphparaSLPAPTIQSLNlswnrfravpDLRDlpLRYLSLDGNP 217
Cdd:PLN00113 221 YNNLSgeiPYEIGGLTSLN-----HLDLVYN------------NLTGPIPSSLG----------NLKN--LQYLFLYQNK 271

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67972425  218 LATINPDAFMGLAGLTHLSLA--SLQG-------------ILHL--------PPHGFRELPGLQVLDLSGNpklKWAGaE 274
Cdd:PLN00113 272 LSGPIPPSIFSLQKLISLDLSdnSLSGeipelviqlqnleILHLfsnnftgkIPVALTSLPRLQVLQLWSN---KFSG-E 347

                        250       260
                 ....*....|....*....|....*....
gi 67972425  275 VFSGLGL---LQELDLSGSSLV-PLPEML 299
Cdd:PLN00113 348 IPKNLGKhnnLTVLDLSTNNLTgEIPEGL 376
LRR_8 pfam13855
Leucine rich repeat;
109-170 2.50e-04

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 38.66  E-value: 2.50e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 67972425   109 RYLESLDLSHNGLAALPAEIFTS-SPLSDINLSHNRLREVSISAFtthSQGRAL-HVDLSHNLI 170
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKGlSNLKVLDLSNNLLTTLSPGAF---SGLPSLrYLDLSGNRL 61
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 87-247 3.16e-04

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 42.53  E-value: 3.16e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67972425   87 LAGLDLSYNLLTSIMPSAFSRLRYLESLDLSHNGLAA-LPAEIF-TSSPLSDINLSHNRLR----EVSISAFTThsqgra 160
Cdd:PLN00113  71 VVSIDLSGKNISGKISSAIFRLPYIQTINLSNNQLSGpIPDDIFtTSSSLRYLNLSNNNFTgsipRGSIPNLET------ 144

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67972425  161 lhVDLSHNLIHRLLPhparaslpaptiQSLNLSWNrfravpdlrdlpLRYLSLDGNPLATINPDAFMGLAGLTHLSLASL 240
Cdd:PLN00113 145 --LDLSNNMLSGEIP------------NDIGSFSS------------LKVLDLGGNVLVGKIPNSLTNLTSLEFLTLASN 198


                 ....*..
gi 67972425  241 QGILHLP 247
Cdd:PLN00113 199 QLVGQIP 205
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 60-275 7.06e-04

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 41.19  E-value: 7.06e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67972425  60 DTAHLDLSSNRLETVNESV-LAGPGYTTLAGL---DLSYNLLTSIMPSAFSRLR---YLESLDLSHNGLAALPAEIFT-- 130
Cdd:cd00116  52 SLKELCLSLNETGRIPRGLqSLLQGLTKGCGLqelDLSDNALGPDGCGVLESLLrssSLQELKLNNNGLGDRGLRLLAkg 131

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67972425 131 ----SSPLSDINLSHNRL-REVSISAFTTHSQGRALH-VDLSHNLI-HRLLPHPARASLPAPTIQSLNLSWNRFR----- 198
Cdd:cd00116 132 lkdlPPALEKLVLGRNRLeGASCEALAKALRANRDLKeLNLANNGIgDAGIRALAEGLKANCNLEVLDLNNNGLTdegas 211

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67972425 199 ----AVPDLRDLplRYLSLDGNPL-----ATINPDAFMGLAGLTHLSLASLqgilHLPPHGFREL-------PGLQVLDL 262
Cdd:cd00116 212 alaeTLASLKSL--EVLNLGDNNLtdagaAALASALLSPNISLLTLSLSCN----DITDDGAKDLaevlaekESLLELDL 285

                       250
                ....*....|...
gi 67972425 263 SGNpKLKWAGAEV 275
Cdd:cd00116 286 RGN-KFGEEGAQL 297
PLN03150 PLN03150
hypothetical protein; Provisional
 89-144 8.78e-04

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 41.34  E-value: 8.78e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 67972425   89 GLDLSYNLLTSIMPSAFSRLRYLESLDLSHNGL-AALPAEIFTSSPLSDINLSHNRL 144
Cdd:PLN03150 422 GLGLDNQGLRGFIPNDISKLRHLQSINLSGNSIrGNIPPSLGSITSLEVLDLSYNSF 478
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
63-234 1.01e-03

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 40.69  E-value: 1.01e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67972425  63 HLDLSSNRLETVNEsvLAGPgyTTLAGLDLSYNLLTSImpSAFSRLRYLESLDLSHNGLAALPAEIFTSSPLSDINLSHN 142
Cdd:COG4886 232 TLDLSNNQLTDLPE--LGNL--TNLEELDLSNNQLTDL--PPLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLL 305

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67972425 143 RLREVSISAFTTHSQGRALHVDLSHNLIHRLLPHPARASLPAPTIQSLNLSWNRFRAVPDLRDLPLRYLSLDGNPLATIN 222
Cdd:COG4886 306 LLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALL 385

                       170
                ....*....|..
gi 67972425 223 PDAFMGLAGLTH 234
Cdd:COG4886 386 LLTLLLLLLTTT 397
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 90-215 1.50e-03

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 40.60  E-value: 1.50e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67972425   90 LDLSYNLLTSIMPSAFSRLRYLESLDLSHNGLAALPAEIFTSSPLSDINLSHNRLREVSISAFTTHSQgrALHVDLSHNL 169
Cdd:PLN00113 433 LDISNNNLQGRINSRKWDMPSLQMLSLARNKFFGGLPDSFGSKRLENLDLSRNQFSGAVPRKLGSLSE--LMQLKLSENK 510

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 67972425  170 IHRLLPHPARAslpAPTIQSLNLSWNR--------FRAVPDLRDLPLRYLSLDG 215
Cdd:PLN00113 511 LSGEIPDELSS---CKKLVSLDLSHNQlsgqipasFSEMPVLSQLDLSQNQLSG 561
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 83-265 1.58e-03

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 40.60  E-value: 1.58e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67972425   83 GYTTLAGLDLSYNLLTSIMPSAFSRLRYLESLDLSHNGLAA-LPAEIFTSSPLSDINLSHNRLREvSISAFTTHSQG-RA 160
Cdd:PLN00113 234 GLTSLNHLDLVYNNLTGPIPSSLGNLKNLQYLFLYQNKLSGpIPPSIFSLQKLISLDLSDNSLSG-EIPELVIQLQNlEI 312

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67972425  161 LHVdLSHNLIHRLlphP-ARASLpaPTIQSLNLSWNRFRA-VPdlRDL----PLRYLSLDGNPLATINPDAFMGLAGLTH 234
Cdd:PLN00113 313 LHL-FSNNFTGKI---PvALTSL--PRLQVLQLWSNKFSGeIP--KNLgkhnNLTVLDLSTNNLTGEIPEGLCSSGNLFK 384

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 67972425  235 LSL--ASLQGilHLP-----------------------PHGFRELPGLQVLDLSGN 265
Cdd:PLN00113 385 LILfsNSLEG--EIPkslgacrslrrvrlqdnsfsgelPSEFTKLPLVYFLDISNN 438
LRR_8 pfam13855
Leucine rich repeat;
255-308 2.82e-03

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 35.58  E-value: 2.82e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 67972425   255 PGLQVLDLSGNpKLKWAGAEVFSGLGLLQELDLSGSSLVPLPEMLLHHLPALQS 308
Cdd:pfam13855   1 PNLRSLDLSNN-RLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRY 53
LRR_8 pfam13855
Leucine rich repeat;
134-197 5.84e-03

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 34.81  E-value: 5.84e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 67972425   134 LSDINLSHNRLREVSISAFTTHSQGRALhvDLSHNLIHRLLPHpARASLPAptIQSLNLSWNRF 197
Cdd:pfam13855   3 LRSLDLSNNRLTSLDDGAFKGLSNLKVL--DLSNNLLTTLSPG-AFSGLPS--LRYLDLSGNRL 61
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH