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Conserved domains on  [gi|237757318|ref|NP_001025148|]
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complement factor H-related protein C isoform 1 precursor [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PHA02927 super family cl33700
secreted complement-binding protein; Provisional
510-744 2.43e-22

secreted complement-binding protein; Provisional


The actual alignment was detected with superfamily member PHA02927:

Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 97.42  E-value: 2.43e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 510 ISCPPPPQIP------NTQVIETTVKYLDGEKLSVLCQDNYLTQD--PEEMMCKDGRWQSLPHCIEKiPCSQPPTIEHGS 581
Cdd:PHA02927  18 LSCCTIPSRPinmkfkNSVETDANANYNIGDTIEYLCLPGYRKQKmgPIYAKCTGTGWTLFNQCIKR-RCPSPRDIDNGQ 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 582 IKLPRTsekrrksiefsshEHGTTFSYVCDDGFRIPEENGVACYMGK-----WS-TPPRCVGLPCGPPPSIPLGTVSLEL 655
Cdd:PHA02927  97 LDIGGV-------------DFGSSITYSCNSGYQLIGESKSYCELGStgsmvWNpEAPICESVKCQSPPSISNGRHNGYE 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 656 ESYQHGEEVTYHCSTGFGIDGPALIKCEGGKWSDPPKCIKTDCDiLPTIENAIIRGKNKKSYRTGEQVTVRCQSPYQMNG 735
Cdd:PHA02927 164 DFYTDGSVVTYSCNSGYSLIGNSGVLCSGGEWSDPPTCQIVKCP-HPTISNGYLSSGFKRSYSYNDNVDFKCKYGYKLSG 242

                 ....*....
gi 237757318 736 SDTVTCING 744
Cdd:PHA02927 243 SSSSTCSPG 251
PHA02927 super family cl33700
secreted complement-binding protein; Provisional
208-448 3.23e-20

secreted complement-binding protein; Provisional


The actual alignment was detected with superfamily member PHA02927:

Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 91.25  E-value: 3.23e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 208 CIKSC----ERPV---FENSVTKNNSTWFKLNDKLDYECLIGYEneyKHTKGSI--TCTYYGWSDTPSCYEIECSVP--I 276
Cdd:PHA02927  16 CVLSCctipSRPInmkFKNSVETDANANYNIGDTIEYLCLPGYR---KQKMGPIyaKCTGTGWTLFNQCIKRRCPSPrdI 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 277 LDRKLVVSprkeKYRVGDLLEFSCRSGHRVGPDSVQCYHFG------WSPSFPTCKAgqvASCAQPPEIPNGEINGAKRV 350
Cdd:PHA02927  93 DNGQLDIG----GVDFGSSITYSCNSGYQLIGESKSYCELGstgsmvWNPEAPICES---VKCQSPPSISNGRHNGYEDF 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 351 eYSHGEVVGYDCKPRFLLKGPNKIQCVDGMWTTLPVCveEERTCGDiPELEHGSVKFSVP-PYHHGDSVEFTCAETFTMI 429
Cdd:PHA02927 166 -YTDGSVVTYSCNSGYSLIGNSGVLCSGGEWSDPPTC--QIVKCPH-PTISNGYLSSGFKrSYSYNDNVDFKCKYGYKLS 241
                        250       260
                 ....*....|....*....|.
gi 237757318 430 GLGSVFCLSGK-WT-QLPKCV 448
Cdd:PHA02927 242 GSSSSTCSPGNtWQpELPKCV 262
PHA02927 super family cl33700
secreted complement-binding protein; Provisional
635-861 5.97e-15

secreted complement-binding protein; Provisional


The actual alignment was detected with superfamily member PHA02927:

Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 75.84  E-value: 5.97e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 635 CVgLPCGPPPSIPLGTV---SLELES---YQHGEEVTYHCSTGFGID--GPALIKCEGGKWSDPPKCIKTDCDILPTIEN 706
Cdd:PHA02927  16 CV-LSCCTIPSRPINMKfknSVETDAnanYNIGDTIEYLCLPGYRKQkmGPIYAKCTGTGWTLFNQCIKRRCPSPRDIDN 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 707 AIIrgkNKKSYRTGEQVTVRCQSPYQMNGSDTVTCINGR-----WIGK-PVCKDSrgKCGPPPPIDNGDITSlslpeYEP 780
Cdd:PHA02927  95 GQL---DIGGVDFGSSITYSCNSGYQLIGESKSYCELGStgsmvWNPEaPICESV--KCQSPPSISNGRHNG-----YED 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 781 F----SSVDYQCQKYYLLKGKKTITCRNGKWSEPPTC-LHACIIPenimearKIILKWRHT--KNIYSHSgEDIEFECKY 853
Cdd:PHA02927 165 FytdgSVVTYSCNSGYSLIGNSGVLCSGGEWSDPPTCqIVKCPHP-------TISNGYLSSgfKRSYSYN-DNVDFKCKY 236

                 ....*...
gi 237757318 854 GYhKARGS 861
Cdd:PHA02927 237 GY-KLSGS 243
PHA02927 super family cl33700
secreted complement-binding protein; Provisional
50-210 1.29e-11

secreted complement-binding protein; Provisional


The actual alignment was detected with superfamily member PHA02927:

Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 65.83  E-value: 1.29e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318  50 VSIGNKYSYKCDNGFSPpSGIFWDYLRCTVQG---WEPEVPCVR--KCVFH-YVENGQSAYWEKIYVQGQSLKVQCYNGY 123
Cdd:PHA02927 102 VDFGSSITYSCNSGYQL-IGESKSYCELGSTGsmvWNPEAPICEsvKCQSPpSISNGRHNGYEDFYTDGSVVTYSCNSGY 180
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 124 SLQnGQDTMTCTENGWSPPPKCIRIKTCSVSdieIENGFFSESF-RTYALNRETSYRCKQGYvtNTGETSGSITCLQNGW 202
Cdd:PHA02927 181 SLI-GNSGVLCSGGEWSDPPTCQIVKCPHPT---ISNGYLSSGFkRSYSYNDNVDFKCKYGY--KLSGSSSSTCSPGNTW 254

                 ....*....
gi 237757318 203 SPQ-PSCIK 210
Cdd:PHA02927 255 QPElPKCVR 263
 
Name Accession Description Interval E-value
PHA02927 PHA02927
secreted complement-binding protein; Provisional
510-744 2.43e-22

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 97.42  E-value: 2.43e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 510 ISCPPPPQIP------NTQVIETTVKYLDGEKLSVLCQDNYLTQD--PEEMMCKDGRWQSLPHCIEKiPCSQPPTIEHGS 581
Cdd:PHA02927  18 LSCCTIPSRPinmkfkNSVETDANANYNIGDTIEYLCLPGYRKQKmgPIYAKCTGTGWTLFNQCIKR-RCPSPRDIDNGQ 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 582 IKLPRTsekrrksiefsshEHGTTFSYVCDDGFRIPEENGVACYMGK-----WS-TPPRCVGLPCGPPPSIPLGTVSLEL 655
Cdd:PHA02927  97 LDIGGV-------------DFGSSITYSCNSGYQLIGESKSYCELGStgsmvWNpEAPICESVKCQSPPSISNGRHNGYE 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 656 ESYQHGEEVTYHCSTGFGIDGPALIKCEGGKWSDPPKCIKTDCDiLPTIENAIIRGKNKKSYRTGEQVTVRCQSPYQMNG 735
Cdd:PHA02927 164 DFYTDGSVVTYSCNSGYSLIGNSGVLCSGGEWSDPPTCQIVKCP-HPTISNGYLSSGFKRSYSYNDNVDFKCKYGYKLSG 242

                 ....*....
gi 237757318 736 SDTVTCING 744
Cdd:PHA02927 243 SSSSTCSPG 251
PHA02927 PHA02927
secreted complement-binding protein; Provisional
208-448 3.23e-20

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 91.25  E-value: 3.23e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 208 CIKSC----ERPV---FENSVTKNNSTWFKLNDKLDYECLIGYEneyKHTKGSI--TCTYYGWSDTPSCYEIECSVP--I 276
Cdd:PHA02927  16 CVLSCctipSRPInmkFKNSVETDANANYNIGDTIEYLCLPGYR---KQKMGPIyaKCTGTGWTLFNQCIKRRCPSPrdI 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 277 LDRKLVVSprkeKYRVGDLLEFSCRSGHRVGPDSVQCYHFG------WSPSFPTCKAgqvASCAQPPEIPNGEINGAKRV 350
Cdd:PHA02927  93 DNGQLDIG----GVDFGSSITYSCNSGYQLIGESKSYCELGstgsmvWNPEAPICES---VKCQSPPSISNGRHNGYEDF 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 351 eYSHGEVVGYDCKPRFLLKGPNKIQCVDGMWTTLPVCveEERTCGDiPELEHGSVKFSVP-PYHHGDSVEFTCAETFTMI 429
Cdd:PHA02927 166 -YTDGSVVTYSCNSGYSLIGNSGVLCSGGEWSDPPTC--QIVKCPH-PTISNGYLSSGFKrSYSYNDNVDFKCKYGYKLS 241
                        250       260
                 ....*....|....*....|.
gi 237757318 430 GLGSVFCLSGK-WT-QLPKCV 448
Cdd:PHA02927 242 GSSSSTCSPGNtWQpELPKCV 262
PHA02927 PHA02927
secreted complement-binding protein; Provisional
635-861 5.97e-15

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 75.84  E-value: 5.97e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 635 CVgLPCGPPPSIPLGTV---SLELES---YQHGEEVTYHCSTGFGID--GPALIKCEGGKWSDPPKCIKTDCDILPTIEN 706
Cdd:PHA02927  16 CV-LSCCTIPSRPINMKfknSVETDAnanYNIGDTIEYLCLPGYRKQkmGPIYAKCTGTGWTLFNQCIKRRCPSPRDIDN 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 707 AIIrgkNKKSYRTGEQVTVRCQSPYQMNGSDTVTCINGR-----WIGK-PVCKDSrgKCGPPPPIDNGDITSlslpeYEP 780
Cdd:PHA02927  95 GQL---DIGGVDFGSSITYSCNSGYQLIGESKSYCELGStgsmvWNPEaPICESV--KCQSPPSISNGRHNG-----YED 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 781 F----SSVDYQCQKYYLLKGKKTITCRNGKWSEPPTC-LHACIIPenimearKIILKWRHT--KNIYSHSgEDIEFECKY 853
Cdd:PHA02927 165 FytdgSVVTYSCNSGYSLIGNSGVLCSGGEWSDPPTCqIVKCPHP-------TISNGYLSSgfKRSYSYN-DNVDFKCKY 236

                 ....*...
gi 237757318 854 GYhKARGS 861
Cdd:PHA02927 237 GY-KLSGS 243
PHA02927 PHA02927
secreted complement-binding protein; Provisional
50-210 1.29e-11

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 65.83  E-value: 1.29e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318  50 VSIGNKYSYKCDNGFSPpSGIFWDYLRCTVQG---WEPEVPCVR--KCVFH-YVENGQSAYWEKIYVQGQSLKVQCYNGY 123
Cdd:PHA02927 102 VDFGSSITYSCNSGYQL-IGESKSYCELGSTGsmvWNPEAPICEsvKCQSPpSISNGRHNGYEDFYTDGSVVTYSCNSGY 180
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 124 SLQnGQDTMTCTENGWSPPPKCIRIKTCSVSdieIENGFFSESF-RTYALNRETSYRCKQGYvtNTGETSGSITCLQNGW 202
Cdd:PHA02927 181 SLI-GNSGVLCSGGEWSDPPTCQIVKCPHPT---ISNGYLSSGFkRSYSYNDNVDFKCKYGY--KLSGSSSSTCSPGNTW 254

                 ....*....
gi 237757318 203 SPQ-PSCIK 210
Cdd:PHA02927 255 QPElPKCVR 263
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
759-813 2.76e-10

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 56.70  E-value: 2.76e-10
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 237757318 759 CGPPPPIDNGDITSlSLPEYEPFSSVDYQCQKYYLLKGKKTITCR-NGKWS-EPPTC 813
Cdd:cd00033    1 CPPPPVPENGTVTG-SKGSYSYGSTVTYSCNEGYTLVGSSTITCTeNGGWSpPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
640-694 1.18e-09

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 54.78  E-value: 1.18e-09
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 237757318 640 CGPPPSIPLGTVSLELESYQHGEEVTYHCSTGFGIDGPALIKC-EGGKWSD-PPKCI 694
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCtENGGWSPpPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
640-693 8.57e-09

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 52.14  E-value: 8.57e-09
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 237757318   640 CGPPPSIPLGTVSLELESYQHGEEVTYHCSTGFGIDGPALIKC-EGGKWSDP-PKC 693
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITClENGTWSPPpPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
394-448 9.37e-09

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 52.08  E-value: 9.37e-09
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 237757318 394 CGDIPELEHGSVKFSVPPYHHGDSVEFTCAETFTMIGLGSVFCL-SGKWTQ-LPKCV 448
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTeNGGWSPpPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
759-813 1.73e-08

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 51.37  E-value: 1.73e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 237757318   759 CGPPPPIDNGDITSLSlPEYEPFSSVDYQCQKYYLLKGKKTITCR-NGKWS-EPPTC 813
Cdd:smart00032   1 CPPPPDIENGTVTSSS-GTYSYGDTVTYSCDPGYTLIGSSTITCLeNGTWSpPPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
394-447 8.73e-08

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 49.45  E-value: 8.73e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 237757318   394 CGDIPELEHGSVKFSVPPYHHGDSVEFTCAETFTMIGLGSVFCL-SGKWT-QLPKC 447
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLeNGTWSpPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
698-752 4.35e-07

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 47.49  E-value: 4.35e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 237757318  698 CDILPTIENAIIRGKnKKSYRTGEQVTVRCQSPYQMNGSDTVTCI-NGRWIGK-PVC 752
Cdd:pfam00084   1 CPPPPDIPNGKVSAT-KNEYNYGASVSYECDPGYRLVGSPTITCQeDGTWSPPfPEC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
272-325 2.33e-06

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 45.57  E-value: 2.33e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 237757318  272 CSVPILDRKLVVSPRKEKYRVGDLLEFSCRSGHR-VGPDSVQC-YHFGWSPSFPTC 325
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRlVGSPTITCqEDGTWSPPFPEC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
759-813 5.21e-06

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 44.41  E-value: 5.21e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 237757318  759 CGPPPPIDNGDITSLSlPEYEPFSSVDYQCQKYYLLKGKKTITCR-NGKWS-EPPTC 813
Cdd:pfam00084   1 CPPPPDIPNGKVSATK-NEYNYGASVSYECDPGYRLVGSPTITCQeDGTWSpPFPEC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
97-146 7.43e-06

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 43.99  E-value: 7.43e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 237757318  97 VENGQSAYWEKIYVQGQSLKVQCYNGYSLQnGQDTMTCTENG-WSP-PPKCI 146
Cdd:cd00033    7 PENGTVTGSKGSYSYGSTVTYSCNEGYTLV-GSSTITCTENGgWSPpPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
97-145 1.85e-05

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 42.90  E-value: 1.85e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|.
gi 237757318    97 VENGQSAYWEKIYVQGQSLKVQCYNGYSLQnGQDTMTCTENG-WSPP-PKC 145
Cdd:smart00032   7 IENGTVTSSSGTYSYGDTVTYSCDPGYTLI-GSSTITCLENGtWSPPpPTC 56
 
Name Accession Description Interval E-value
PHA02927 PHA02927
secreted complement-binding protein; Provisional
510-744 2.43e-22

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 97.42  E-value: 2.43e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 510 ISCPPPPQIP------NTQVIETTVKYLDGEKLSVLCQDNYLTQD--PEEMMCKDGRWQSLPHCIEKiPCSQPPTIEHGS 581
Cdd:PHA02927  18 LSCCTIPSRPinmkfkNSVETDANANYNIGDTIEYLCLPGYRKQKmgPIYAKCTGTGWTLFNQCIKR-RCPSPRDIDNGQ 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 582 IKLPRTsekrrksiefsshEHGTTFSYVCDDGFRIPEENGVACYMGK-----WS-TPPRCVGLPCGPPPSIPLGTVSLEL 655
Cdd:PHA02927  97 LDIGGV-------------DFGSSITYSCNSGYQLIGESKSYCELGStgsmvWNpEAPICESVKCQSPPSISNGRHNGYE 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 656 ESYQHGEEVTYHCSTGFGIDGPALIKCEGGKWSDPPKCIKTDCDiLPTIENAIIRGKNKKSYRTGEQVTVRCQSPYQMNG 735
Cdd:PHA02927 164 DFYTDGSVVTYSCNSGYSLIGNSGVLCSGGEWSDPPTCQIVKCP-HPTISNGYLSSGFKRSYSYNDNVDFKCKYGYKLSG 242

                 ....*....
gi 237757318 736 SDTVTCING 744
Cdd:PHA02927 243 SSSSTCSPG 251
PHA02927 PHA02927
secreted complement-binding protein; Provisional
208-448 3.23e-20

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 91.25  E-value: 3.23e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 208 CIKSC----ERPV---FENSVTKNNSTWFKLNDKLDYECLIGYEneyKHTKGSI--TCTYYGWSDTPSCYEIECSVP--I 276
Cdd:PHA02927  16 CVLSCctipSRPInmkFKNSVETDANANYNIGDTIEYLCLPGYR---KQKMGPIyaKCTGTGWTLFNQCIKRRCPSPrdI 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 277 LDRKLVVSprkeKYRVGDLLEFSCRSGHRVGPDSVQCYHFG------WSPSFPTCKAgqvASCAQPPEIPNGEINGAKRV 350
Cdd:PHA02927  93 DNGQLDIG----GVDFGSSITYSCNSGYQLIGESKSYCELGstgsmvWNPEAPICES---VKCQSPPSISNGRHNGYEDF 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 351 eYSHGEVVGYDCKPRFLLKGPNKIQCVDGMWTTLPVCveEERTCGDiPELEHGSVKFSVP-PYHHGDSVEFTCAETFTMI 429
Cdd:PHA02927 166 -YTDGSVVTYSCNSGYSLIGNSGVLCSGGEWSDPPTC--QIVKCPH-PTISNGYLSSGFKrSYSYNDNVDFKCKYGYKLS 241
                        250       260
                 ....*....|....*....|.
gi 237757318 430 GLGSVFCLSGK-WT-QLPKCV 448
Cdd:PHA02927 242 GSSSSTCSPGNtWQpELPKCV 262
PHA02927 PHA02927
secreted complement-binding protein; Provisional
603-814 6.57e-18

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 84.70  E-value: 6.57e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 603 GTTFSYVCDDGFRIPEENGV--ACYMGKWSTPPRCVGLPCGPPPSIPLGtvSLELESYQHGEEVTYHCSTGFGIDGPALI 680
Cdd:PHA02927  47 GDTIEYLCLPGYRKQKMGPIyaKCTGTGWTLFNQCIKRRCPSPRDIDNG--QLDIGGVDFGSSITYSCNSGYQLIGESKS 124
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 681 KCEGGK-----WS-DPPKCIKTDCDILPTIENAIIRGKNKkSYRTGEQVTVRCQSPYQMNGSDTVTCINGRWIGKPVCKD 754
Cdd:PHA02927 125 YCELGStgsmvWNpEAPICESVKCQSPPSISNGRHNGYED-FYTDGSVVTYSCNSGYSLIGNSGVLCSGGEWSDPPTCQI 203
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 237757318 755 SrgKCgPPPPIDNGDITSLSLPEYEPFSSVDYQCQKYYLLKGKKTITCRNGKWSEP--PTCL 814
Cdd:PHA02927 204 V--KC-PHPTISNGYLSSGFKRSYSYNDNVDFKCKYGYKLSGSSSSTCSPGNTWQPelPKCV 262
PHA02831 PHA02831
EEV host range protein; Provisional
651-802 2.29e-15

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 77.34  E-value: 2.29e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 651 VSLELESYQHGEEVTYHCSTGFGidgPALIKCEGGKWSDPPKCI-KTDCDILPTIENAIIRGKNKKsYRTGEQVTVRCQ- 728
Cdd:PHA02831  33 DSYENKVYEENENLEYKCNNNFD---KVFVTCNNGSWSTKNMCIgKRNCKDPVTILNGYIKNKKDQ-YSFGDSVTYACKv 108
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 237757318 729 ---SPYQMNGSDTVTCINGRWIGK-PVCKDSRGKCgppPPIDNGDITSLSLPEYEPfSSVDYQCQKYYLLKGKKTITC 802
Cdd:PHA02831 109 nklEKYSIVGNETVKCINKQWVPKyPVCKLIRCKY---PALQNGFLNVFEKKFYYG-DIVNFKCKKGFILLGSSVSTC 182
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
516-774 3.20e-15

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 77.82  E-value: 3.20e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 516 PQIPNTQVIETTVKYLDGEKLSVLCQDNYLTQDPEEMmCKDGRWQSlphcieKIPCSQPPTIEHgsiklpRTSEKRRKSI 595
Cdd:PHA02954  24 PTMNNAKLTSTETSFNDKQKVTFTCDSGYYSLDPNAV-CETDKWKY------ENPCKKMCTVSD------YVSELYDKPL 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 596 efssHEHGTTFSYVCDDG---FRIPEENGVAcymgKWSTPPRCVGLPCgPPPSIPLGTVSLELESYQHGEEVTYHCSTGF 672
Cdd:PHA02954  91 ----YEVNSTITLICKDEtkyFRCEEKNGNT----SWNDTVTCPNAEC-QPLQLEHGSCQPVKEKYSFGEHITINCDVGY 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 673 GIDGPALIKCEGGKWSDPPKCiKTDCDIlPTIENAIIRGknkKSYRTGEQVTVRCQSPYQMNGSDTVTCINGRWIGK-PV 751
Cdd:PHA02954 162 EVIGASYISCTANSWNVIPSC-QQKCDI-PSLSNGLISG---STFSIGGVIHLSCKSGFTLTGSPSSTCIDGKWNPVlPI 236
                        250       260
                 ....*....|....*....|....*
gi 237757318 752 CKDSRGKCGP--PPPIDNGDITSLS 774
Cdd:PHA02954 237 CVRSNEEFDPvdDGPDDETDLSKLS 261
PHA02927 PHA02927
secreted complement-binding protein; Provisional
635-861 5.97e-15

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 75.84  E-value: 5.97e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 635 CVgLPCGPPPSIPLGTV---SLELES---YQHGEEVTYHCSTGFGID--GPALIKCEGGKWSDPPKCIKTDCDILPTIEN 706
Cdd:PHA02927  16 CV-LSCCTIPSRPINMKfknSVETDAnanYNIGDTIEYLCLPGYRKQkmGPIYAKCTGTGWTLFNQCIKRRCPSPRDIDN 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 707 AIIrgkNKKSYRTGEQVTVRCQSPYQMNGSDTVTCINGR-----WIGK-PVCKDSrgKCGPPPPIDNGDITSlslpeYEP 780
Cdd:PHA02927  95 GQL---DIGGVDFGSSITYSCNSGYQLIGESKSYCELGStgsmvWNPEaPICESV--KCQSPPSISNGRHNG-----YED 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 781 F----SSVDYQCQKYYLLKGKKTITCRNGKWSEPPTC-LHACIIPenimearKIILKWRHT--KNIYSHSgEDIEFECKY 853
Cdd:PHA02927 165 FytdgSVVTYSCNSGYSLIGNSGVLCSGGEWSDPPTCqIVKCPHP-------TISNGYLSSgfKRSYSYN-DNVDFKCKY 236

                 ....*...
gi 237757318 854 GYhKARGS 861
Cdd:PHA02927 237 GY-KLSGS 243
PHA02927 PHA02927
secreted complement-binding protein; Provisional
290-508 2.10e-13

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 71.22  E-value: 2.10e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 290 YRVGDLLEFSCRSGHR---VGPDSVQCYHFGWSpSFPTCKAGQvasCAQPPEIPNGEINGAKrVEYshGEVVGYDCKPRF 366
Cdd:PHA02927  44 YNIGDTIEYLCLPGYRkqkMGPIYAKCTGTGWT-LFNQCIKRR---CPSPRDIDNGQLDIGG-VDF--GSSITYSCNSGY 116
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 367 LLKGPNKIQCVDG-----MWT-TLPVCveEERTCGDIPELEHGSVKFSVPPYHHGDSVEFTCAETFTMIGLGSVFCLSGK 440
Cdd:PHA02927 117 QLIGESKSYCELGstgsmVWNpEAPIC--ESVKCQSPPSISNGRHNGYEDFYTDGSVVTYSCNSGYSLIGNSGVLCSGGE 194
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 237757318 441 WTQLPKCvatdQLEKCRVLKSTDIEAIKPKRKEFQHNSTMYYKCRDKQEY---EHSICINGK-WNPE-PNCIR 508
Cdd:PHA02927 195 WSDPPTC----QIVKCPHPTISNGYLSSGFKRSYSYNDNVDFKCKYGYKLsgsSSSTCSPGNtWQPElPKCVR 263
PHA02831 PHA02831
EEV host range protein; Provisional
594-755 3.89e-13

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 70.41  E-value: 3.89e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 594 SIEFSSHEHGTTFSYVCDDGFripEENGVACYMGKWSTPPRCVG-LPCGPPPSIPLGTVSLELESYQHGEEVTYHCSTG- 671
Cdd:PHA02831  34 SYENKVYEENENLEYKCNNNF---DKVFVTCNNGSWSTKNMCIGkRNCKDPVTILNGYIKNKKDQYSFGDSVTYACKVNk 110
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 672 ---FGIDGPALIKCEGGKW-SDPPKCIKTDCDiLPTIENAIIRGKNKKSYrTGEQVTVRCQSPYQMNGSDTVTC-INGRW 746
Cdd:PHA02831 111 lekYSIVGNETVKCINKQWvPKYPVCKLIRCK-YPALQNGFLNVFEKKFY-YGDIVNFKCKKGFILLGSSVSTCdINSIW 188
                        170
                 ....*....|.
gi 237757318 747 I-GKPVC-KDS 755
Cdd:PHA02831 189 YpGIPKCvKDK 199
PHA02831 PHA02831
EEV host range protein; Provisional
217-391 2.36e-12

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 68.10  E-value: 2.36e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 217 FENSVTKNNSTwFKLNDKLDYECLIGYENEYkhtkgsITCTYYGWSDTPSCY-EIECSVPILDRKLVVSPRKEKYRVGDL 295
Cdd:PHA02831  29 YSNVDSYENKV-YEENENLEYKCNNNFDKVF------VTCNNGSWSTKNMCIgKRNCKDPVTILNGYIKNKKDQYSFGDS 101
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 296 LEFSCRSGHR-----VGPDSVQCYHFGWSPSFPTCKagqVASCaQPPEIPNGEINGAKRvEYSHGEVVGYDCKPRFLLKG 370
Cdd:PHA02831 102 VTYACKVNKLekysiVGNETVKCINKQWVPKYPVCK---LIRC-KYPALQNGFLNVFEK-KFYYGDIVNFKCKKGFILLG 176
                        170       180
                 ....*....|....*....|...
gi 237757318 371 PNKIQC-VDGMWT-TLPVCVEEE 391
Cdd:PHA02831 177 SSVSTCdINSIWYpGIPKCVKDK 199
PHA02927 PHA02927
secreted complement-binding protein; Provisional
50-210 1.29e-11

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 65.83  E-value: 1.29e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318  50 VSIGNKYSYKCDNGFSPpSGIFWDYLRCTVQG---WEPEVPCVR--KCVFH-YVENGQSAYWEKIYVQGQSLKVQCYNGY 123
Cdd:PHA02927 102 VDFGSSITYSCNSGYQL-IGESKSYCELGSTGsmvWNPEAPICEsvKCQSPpSISNGRHNGYEDFYTDGSVVTYSCNSGY 180
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 124 SLQnGQDTMTCTENGWSPPPKCIRIKTCSVSdieIENGFFSESF-RTYALNRETSYRCKQGYvtNTGETSGSITCLQNGW 202
Cdd:PHA02927 181 SLI-GNSGVLCSGGEWSDPPTCQIVKCPHPT---ISNGYLSSGFkRSYSYNDNVDFKCKYGY--KLSGSSSSTCSPGNTW 254

                 ....*....
gi 237757318 203 SPQ-PSCIK 210
Cdd:PHA02927 255 QPElPKCVR 263
PHA02831 PHA02831
EEV host range protein; Provisional
149-336 2.12e-11

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 65.40  E-value: 2.12e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 149 KTCSV-----SDIEIENGFFSESfRTYALNRETSYRCKQGYvtntgeTSGSITCLQNGWSPQPSCI--KSCERPV-FENS 220
Cdd:PHA02831  15 KTWCIcvfnkNDAKYSNVDSYEN-KVYEENENLEYKCNNNF------DKVFVTCNNGSWSTKNMCIgkRNCKDPVtILNG 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 221 VTKNNSTWFKLNDKLDYECLIGYENEYKHTKG-SITCTYYGW-SDTPSCYEIECSVPILDRKLVVSPRKeKYRVGDLLEF 298
Cdd:PHA02831  88 YIKNKKDQYSFGDSVTYACKVNKLEKYSIVGNeTVKCINKQWvPKYPVCKLIRCKYPALQNGFLNVFEK-KFYYGDIVNF 166
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 237757318 299 SCRSGHRVGPDSVQC--YHFGWSPSFPTCKAGQVASCAQP 336
Cdd:PHA02831 167 KCKKGFILLGSSVSTcdINSIWYPGIPKCVKDKVHNEIQP 206
PHA02927 PHA02927
secreted complement-binding protein; Provisional
98-325 2.25e-10

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 62.36  E-value: 2.25e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318  98 ENGQSAYWEKIYVQGQSLKVQCYNGYSLQN-GQDTMTCTENGWSPPPKCIRIKTCSVSDIEieNGFFSESFRTYAlnRET 176
Cdd:PHA02927  33 KNSVETDANANYNIGDTIEYLCLPGYRKQKmGPIYAKCTGTGWTLFNQCIKRRCPSPRDID--NGQLDIGGVDFG--SSI 108
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 177 SYRCKQGYVTnTGETSGSITCLQNG---WSPQ-PSC--IKSCERPVFENSVTKNNSTWFKLNDKLDYECLIGYEneyKHT 250
Cdd:PHA02927 109 TYSCNSGYQL-IGESKSYCELGSTGsmvWNPEaPICesVKCQSPPSISNGRHNGYEDFYTDGSVVTYSCNSGYS---LIG 184
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 237757318 251 KGSITCTYYGWSDTPSCYEIECSVPILDRKLVVSPRKEKYRVGDLLEFSCRSGHRV-GPDSVQCYHFG-WSPSFPTC 325
Cdd:PHA02927 185 NSGVLCSGGEWSDPPTCQIVKCPHPTISNGYLSSGFKRSYSYNDNVDFKCKYGYKLsGSSSSTCSPGNtWQPELPKC 261
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
759-813 2.76e-10

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 56.70  E-value: 2.76e-10
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 237757318 759 CGPPPPIDNGDITSlSLPEYEPFSSVDYQCQKYYLLKGKKTITCR-NGKWS-EPPTC 813
Cdd:cd00033    1 CPPPPVPENGTVTG-SKGSYSYGSTVTYSCNEGYTLVGSSTITCTeNGGWSpPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
640-694 1.18e-09

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 54.78  E-value: 1.18e-09
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 237757318 640 CGPPPSIPLGTVSLELESYQHGEEVTYHCSTGFGIDGPALIKC-EGGKWSD-PPKCI 694
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCtENGGWSPpPPTCE 57
PHA02927 PHA02927
secreted complement-binding protein; Provisional
412-636 1.83e-09

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 59.67  E-value: 1.83e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 412 YHHGDSVEFTCAETFTMIGLGSVF--CLSGKWTQLPKCVAtdqlEKCRVLKSTDIEAIKPKRKEFqhNSTMYYKCRDKQE 489
Cdd:PHA02927  44 YNIGDTIEYLCLPGYRKQKMGPIYakCTGTGWTLFNQCIK----RRCPSPRDIDNGQLDIGGVDF--GSSITYSCNSGYQ 117
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 490 Y---EHSICINGK-----WNPEPNCIRKISCPPPPQIPNTQVIETTVKYLDGEKLSVLCQDNYLTQDPEEMMCKDGRWQS 561
Cdd:PHA02927 118 LigeSKSYCELGStgsmvWNPEAPICESVKCQSPPSISNGRHNGYEDFYTDGSVVTYSCNSGYSLIGNSGVLCSGGEWSD 197
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 237757318 562 LPHC-IEKIPcsqPPTIEHGSIKlprTSEKRrksiefsSHEHGTTFSYVCDDGFRIPEENGVACYMGKWSTP--PRCV 636
Cdd:PHA02927 198 PPTCqIVKCP---HPTISNGYLS---SGFKR-------SYSYNDNVDFKCKYGYKLSGSSSSTCSPGNTWQPelPKCV 262
PHA02639 PHA02639
EEV host range protein; Provisional
564-752 5.80e-09

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 58.52  E-value: 5.80e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 564 HCIEKIPCSQPPTIEHGSIklprtSEKRRKsiefssHEHGTTFSYVCDDGFRIPEENGVACYMGK----WST-PPRCVGL 638
Cdd:PHA02639  15 HGVKSIYCDKPDDISNGFI-----TELMEK------YEIGKLIEYTCNTDYALIGDRFRTCIKDKnnaiWSNkAPFCMLK 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 639 PCGPPPSIPLGTVSLELESYQHGEEVTYHCSTGFGID----GPALIKCEGGK-WS-DPPKCIKTDCDiLPTIENAIIRG- 711
Cdd:PHA02639  84 ECNDPPSIINGKIYNKREMYKVGDEIYYVCNEHKGVQyslvGNEKITCIQDKsWKpDPPICKMINCR-FPALQNGYINGi 162
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 237757318 712 -KNKKSYRTgEQVTVRCQSPYQMNGSDTVTC-INGRWIGK-PVC 752
Cdd:PHA02639 163 pSNKKFYYK-TRVGFSCKSGFDLVGEKYSTCnINATWFPSiPTC 205
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
640-693 8.57e-09

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 52.14  E-value: 8.57e-09
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 237757318   640 CGPPPSIPLGTVSLELESYQHGEEVTYHCSTGFGIDGPALIKC-EGGKWSDP-PKC 693
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITClENGTWSPPpPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
394-448 9.37e-09

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 52.08  E-value: 9.37e-09
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 237757318 394 CGDIPELEHGSVKFSVPPYHHGDSVEFTCAETFTMIGLGSVFCL-SGKWTQ-LPKCV 448
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTeNGGWSPpPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
759-813 1.73e-08

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 51.37  E-value: 1.73e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 237757318   759 CGPPPPIDNGDITSLSlPEYEPFSSVDYQCQKYYLLKGKKTITCR-NGKWS-EPPTC 813
Cdd:smart00032   1 CPPPPDIENGTVTSSS-GTYSYGDTVTYSCDPGYTLIGSSTITCLeNGTWSpPPPTC 56
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
211-452 2.18e-08

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 56.63  E-value: 2.18e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 211 SCERPVFENSVTKNNSTWFKLNDKLDYECLIGYENeykhTKGSITCTYYGWSDTPSCYEIeCSVPILDRKLVVSPRkekY 290
Cdd:PHA02954  20 TCTVPTMNNAKLTSTETSFNDKQKVTFTCDSGYYS----LDPNAVCETDKWKYENPCKKM-CTVSDYVSELYDKPL---Y 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 291 RVGDLLEFSCRSGHRVGPDSVQCYHFGWSPSFpTCKAGQvascAQPPEIPNGEINGAKRvEYSHGEVVGYDCKPRFLLKG 370
Cdd:PHA02954  92 EVNSTITLICKDETKYFRCEEKNGNTSWNDTV-TCPNAE----CQPLQLEHGSCQPVKE-KYSFGEHITINCDVGYEVIG 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 371 PNKIQCVDGMWTTLPVCveeERTCgDIPELEHGSVKFSVppYHHGDSVEFTCAETFTMIGLGSVFCLSGKWTQ-LPKCVA 449
Cdd:PHA02954 166 ASYISCTANSWNVIPSC---QQKC-DIPSLSNGLISGST--FSIGGVIHLSCKSGFTLTGSPSSTCIDGKWNPvLPICVR 239

                 ...
gi 237757318 450 TDQ 452
Cdd:PHA02954 240 SNE 242
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
394-447 8.73e-08

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 49.45  E-value: 8.73e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 237757318   394 CGDIPELEHGSVKFSVPPYHHGDSVEFTCAETFTMIGLGSVFCL-SGKWT-QLPKC 447
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLeNGTWSpPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
333-388 9.45e-08

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 49.38  E-value: 9.45e-08
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 237757318 333 CAQPPEIPNGEINGAKRvEYSHGEVVGYDCKPRFLLKGPNKIQCV-DGMWT-TLPVCV 388
Cdd:cd00033    1 CPPPPVPENGTVTGSKG-SYSYGSTVTYSCNEGYTLVGSSTITCTeNGGWSpPPPTCE 57
PHA02831 PHA02831
EEV host range protein; Provisional
282-448 1.31e-07

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 53.84  E-value: 1.31e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 282 VVSPRKEKYRVGDLLEFSCRSGHrvgpDSV--QCYHFGWSPSfPTCKAGQvaSCAQPPEIPNGEINGaKRVEYSHGEVVG 359
Cdd:PHA02831  32 VDSYENKVYEENENLEYKCNNNF----DKVfvTCNNGSWSTK-NMCIGKR--NCKDPVTILNGYIKN-KKDQYSFGDSVT 103
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 360 YDCK----PRFLLKGPNKIQCVDGMWT-TLPVCveEERTCgDIPELEHGSVKFSVPPYHHGDSVEFTCAETFTMIGLGSV 434
Cdd:PHA02831 104 YACKvnklEKYSIVGNETVKCINKQWVpKYPVC--KLIRC-KYPALQNGFLNVFEKKFYYGDIVNFKCKKGFILLGSSVS 180
                        170
                 ....*....|....*.
gi 237757318 435 FC-LSGKWT-QLPKCV 448
Cdd:PHA02831 181 TCdINSIWYpGIPKCV 196
PHA02639 PHA02639
EEV host range protein; Provisional
157-325 1.40e-07

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 54.28  E-value: 1.40e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 157 EIENGFFSESFRTYALNRETSYRCKQGYVTNTGETSGSITCLQNG-WSPQ-PSC-IKSC-ERPVFENSVTKNNSTWFKLN 232
Cdd:PHA02639  27 DISNGFITELMEKYEIGKLIEYTCNTDYALIGDRFRTCIKDKNNAiWSNKaPFCmLKECnDPPSIINGKIYNKREMYKVG 106
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 233 DKLDYECligyeNEYKHTKGS------ITCTY-YGWS-DTPSCYEIECSVPILDRKLVVS-PRKEKYRVGDLLEFSCRSG 303
Cdd:PHA02639 107 DEIYYVC-----NEHKGVQYSlvgnekITCIQdKSWKpDPPICKMINCRFPALQNGYINGiPSNKKFYYKTRVGFSCKSG 181
                        170       180
                 ....*....|....*....|....
gi 237757318 304 HR-VGPDSVQC-YHFGWSPSFPTC 325
Cdd:PHA02639 182 FDlVGEKYSTCnINATWFPSIPTC 205
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
698-753 3.19e-07

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 47.84  E-value: 3.19e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 237757318 698 CDILPTIENAIIRGKnKKSYRTGEQVTVRCQSPYQMNGSDTVTCI-NGRWIGK-PVCK 753
Cdd:cd00033    1 CPPPPVPENGTVTGS-KGSYSYGSTVTYSCNEGYTLVGSSTITCTeNGGWSPPpPTCE 57
Sushi pfam00084
Sushi repeat (SCR repeat);
698-752 4.35e-07

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 47.49  E-value: 4.35e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 237757318  698 CDILPTIENAIIRGKnKKSYRTGEQVTVRCQSPYQMNGSDTVTCI-NGRWIGK-PVC 752
Cdd:pfam00084   1 CPPPPDIPNGKVSAT-KNEYNYGASVSYECDPGYRLVGSPTITCQeDGTWSPPfPEC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
698-752 7.93e-07

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 46.75  E-value: 7.93e-07
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 237757318   698 CDILPTIENAIIRGKNKkSYRTGEQVTVRCQSPYQMNGSDTVTCI-NGRWIGK-PVC 752
Cdd:smart00032   1 CPPPPDIENGTVTSSSG-TYSYGDTVTYSCDPGYTLIGSSTITCLeNGTWSPPpPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
333-387 1.33e-06

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 45.98  E-value: 1.33e-06
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 237757318   333 CAQPPEIPNGEINGAKRvEYSHGEVVGYDCKPRFLLKGPNKIQCV-DGMWT-TLPVC 387
Cdd:smart00032   1 CPPPPDIENGTVTSSSG-TYSYGDTVTYSCDPGYTLIGSSTITCLeNGTWSpPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
272-325 2.33e-06

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 45.57  E-value: 2.33e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 237757318  272 CSVPILDRKLVVSPRKEKYRVGDLLEFSCRSGHR-VGPDSVQC-YHFGWSPSFPTC 325
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRlVGSPTITCqEDGTWSPPFPEC 56
PHA02639 PHA02639
EEV host range protein; Provisional
333-508 2.46e-06

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 50.43  E-value: 2.46e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 333 CAQPPEIPNGEINGAKRvEYSHGEVVGYDCKPRFLLKGPNKIQCV----DGMWTT-LPVCVEEErtCGDIPELEHGSVKF 407
Cdd:PHA02639  22 CDKPDDISNGFITELME-KYEIGKLIEYTCNTDYALIGDRFRTCIkdknNAIWSNkAPFCMLKE--CNDPPSIINGKIYN 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 408 SVPPYHHGDSVEFTCAE----TFTMIGLGSVFCLSGK-WTQLPKCVatdQLEKCR--VLKSTDIEAIkPKRKEFQHNSTM 480
Cdd:PHA02639  99 KREMYKVGDEIYYVCNEhkgvQYSLVGNEKITCIQDKsWKPDPPIC---KMINCRfpALQNGYINGI-PSNKKFYYKTRV 174
                        170       180       190
                 ....*....|....*....|....*....|...
gi 237757318 481 YYKCR---DKQEYEHSIC-INGKWNPE-PNCIR 508
Cdd:PHA02639 175 GFSCKsgfDLVGEKYSTCnINATWFPSiPTCVR 207
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
92-325 3.12e-06

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 50.08  E-value: 3.12e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318  92 CVFHYVENGQSAYWEKIYVQGQSLKVQCYNGYslQNGQDTMTCTENGWSPPPKCIriKTCSVSDI--EIENGFFSE--SF 167
Cdd:PHA02954  21 CTVPTMNNAKLTSTETSFNDKQKVTFTCDSGY--YSLDPNAVCETDKWKYENPCK--KMCTVSDYvsELYDKPLYEvnST 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 168 RTYALNRETSY-RCKQgyvtNTGETSgsitclqngWSPQPSCIKS-CERPVFENSVTKNNSTWFKLNDKLDYECLIGYEn 245
Cdd:PHA02954  97 ITLICKDETKYfRCEE----KNGNTS---------WNDTVTCPNAeCQPLQLEHGSCQPVKEKYSFGEHITINCDVGYE- 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 246 eyKHTKGSITCTYYGWSDTPSCYEiECSVPILDRKLVVSprkEKYRVGDLLEFSCRSGHRV-GPDSVQCYHFGWSPSFPT 324
Cdd:PHA02954 163 --VIGASYISCTANSWNVIPSCQQ-KCDIPSLSNGLISG---STFSIGGVIHLSCKSGFTLtGSPSSTCIDGKWNPVLPI 236

                 .
gi 237757318 325 C 325
Cdd:PHA02954 237 C 237
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
272-326 3.63e-06

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 44.76  E-value: 3.63e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 237757318 272 CSVPILDRKLVVSPRKEKYRVGDLLEFSCRSGHR-VGPDSVQCY-HFGWSPSFPTCK 326
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTlVGSSTITCTeNGGWSPPPPTCE 57
PHA02817 PHA02817
EEV Host range protein; Provisional
635-752 4.18e-06

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 48.78  E-value: 4.18e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 635 CVGLPCGPPPSIPLGTVSLELESYQHGEEVTYHCSTG-----FGIDGPALIKCE-GGKWS-DPPKCIKTDCDiLPTIENA 707
Cdd:PHA02817  19 CDLNKCCYPPSIKNGYIYNKKTEYNIGSNVTFFCGNNtrgvrYTLVGEKNIICEkDGKWNkEFPVCKIIRCR-FPALQNG 97
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 237757318 708 IIRG--KNKKSYRTGEqVTVRCQSPYQMNGSDTVTC-INGRWIGK-PVC 752
Cdd:PHA02817  98 FVNGipDSKKFYYESE-VSFSCKPGFVLIGTKYSVCgINSSWIPKvPIC 145
Sushi pfam00084
Sushi repeat (SCR repeat);
759-813 5.21e-06

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 44.41  E-value: 5.21e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 237757318  759 CGPPPPIDNGDITSLSlPEYEPFSSVDYQCQKYYLLKGKKTITCR-NGKWS-EPPTC 813
Cdd:pfam00084   1 CPPPPDIPNGKVSATK-NEYNYGASVSYECDPGYRLVGSPTITCQeDGTWSpPFPEC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
640-693 5.92e-06

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 44.41  E-value: 5.92e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 237757318  640 CGPPPSIPLGTVSLELESYQHGEEVTYHCSTGFGIDGPALIKC-EGGKWSDP-PKC 693
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCqEDGTWSPPfPEC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
97-146 7.43e-06

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 43.99  E-value: 7.43e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 237757318  97 VENGQSAYWEKIYVQGQSLKVQCYNGYSLQnGQDTMTCTENG-WSP-PPKCI 146
Cdd:cd00033    7 PENGTVTGSKGSYSYGSTVTYSCNEGYTLV-GSSTITCTENGgWSPpPPTCE 57
PHA02831 PHA02831
EEV host range protein; Provisional
472-636 1.80e-05

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 47.29  E-value: 1.80e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 472 KEFQHNSTMYYKCRDKQEYEHSICINGKWNPEPNCIRKISCPPPPQIPNTQVIETTVKYLDGEKLSVLCQDNYLTQ---- 547
Cdd:PHA02831  38 KVYEENENLEYKCNNNFDKVFVTCNNGSWSTKNMCIGKRNCKDPVTILNGYIKNKKDQYSFGDSVTYACKVNKLEKysiv 117
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 548 DPEEMMCKDGRW-QSLPHCieKIPCSQPPTIEHGSIKlprTSEKRrksiefssHEHGTTFSYVCDDGFRIPEENGVACYM 626
Cdd:PHA02831 118 GNETVKCINKQWvPKYPVC--KLIRCKYPALQNGFLN---VFEKK--------FYYGDIVNFKCKKGFILLGSSVSTCDI 184
                        170
                 ....*....|..
gi 237757318 627 GKWSTP--PRCV 636
Cdd:PHA02831 185 NSIWYPgiPKCV 196
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
97-145 1.85e-05

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 42.90  E-value: 1.85e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|.
gi 237757318    97 VENGQSAYWEKIYVQGQSLKVQCYNGYSLQnGQDTMTCTENG-WSPP-PKC 145
Cdd:smart00032   7 IENGTVTSSSGTYSYGDTVTYSCDPGYTLI-GSSTITCLENGtWSPPpPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
333-387 2.25e-05

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 42.49  E-value: 2.25e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 237757318  333 CAQPPEIPNGEINGaKRVEYSHGEVVGYDCKPRFLLKGPNKIQCV-DGMWT-TLPVC 387
Cdd:pfam00084   1 CPPPPDIPNGKVSA-TKNEYNYGASVSYECDPGYRLVGSPTITCQeDGTWSpPFPEC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
272-325 2.30e-05

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 42.51  E-value: 2.30e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 237757318   272 CSVPILDRKLVVSPRKEKYRVGDLLEFSCRSGHR-VGPDSVQCYHFG-WSPSFPTC 325
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTlIGSSTITCLENGtWSPPPPTC 56
PHA02831 PHA02831
EEV host range protein; Provisional
715-855 2.81e-05

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 46.91  E-value: 2.81e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 715 KSYRTGEQVTVRCQSPYQmngSDTVTCINGRWIGKPVCKDSRgKCGPPPPIDNGDITSlSLPEYEPFSSVDYQCQ----K 790
Cdd:PHA02831  38 KVYEENENLEYKCNNNFD---KVFVTCNNGSWSTKNMCIGKR-NCKDPVTILNGYIKN-KKDQYSFGDSVTYACKvnklE 112
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 791 YYLLKGKKTITCRNGKW-SEPPTC-LHACIIP---ENIMEARKiilkwrhtKNIYshSGEDIEFECKYGY 855
Cdd:PHA02831 113 KYSIVGNETVKCINKQWvPKYPVCkLIRCKYPalqNGFLNVFE--------KKFY--YGDIVNFKCKKGF 172
PHA02817 PHA02817
EEV Host range protein; Provisional
266-397 3.02e-05

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 46.09  E-value: 3.02e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 266 SCYEIECSVPILDRKLVVSPRKEKYRVGDLLEFSCRSGHR------VGPDSVQCYHFG-WSPSFPTCKagqVASCaQPPE 338
Cdd:PHA02817  18 LCDLNKCCYPPSIKNGYIYNKKTEYNIGSNVTFFCGNNTRgvrytlVGEKNIICEKDGkWNKEFPVCK---IIRC-RFPA 93
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 237757318 339 IPNGEING-AKRVEYSHGEVVGYDCKPRFLLKG-PNKIQCVDGMW-TTLPVCVEEERTCGDI 397
Cdd:PHA02817  94 LQNGFVNGiPDSKKFYYESEVSFSCKPGFVLIGtKYSVCGINSSWiPKVPICSRDNITYNKI 155
Sushi pfam00084
Sushi repeat (SCR repeat);
394-447 4.52e-05

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 41.72  E-value: 4.52e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 237757318  394 CGDIPELEHGSVKFSVPPYHHGDSVEFTCAETFTMIGLGSVFCL-SGKWTQL-PKC 447
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQeDGTWSPPfPEC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
512-566 1.47e-04

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 40.52  E-value: 1.47e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 237757318 512 CPPPPQIPNTQVIETTVKYLDGEKLSVLCQDNYLTQDPEEMMC-KDGRW-QSLPHCI 566
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCtENGGWsPPPPTCE 57
PHA02817 PHA02817
EEV Host range protein; Provisional
333-451 4.99e-04

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 42.62  E-value: 4.99e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 333 CAQPPEIPNGEINGaKRVEYSHGEVVGYDCKP-----RFLLKGPNKIQC-VDGMWTT-LPVCveeERTCGDIPELEHGSV 405
Cdd:PHA02817  24 CCYPPSIKNGYIYN-KKTEYNIGSNVTFFCGNntrgvRYTLVGEKNIICeKDGKWNKeFPVC---KIIRCRFPALQNGFV 99
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 237757318 406 KfSVP---PYHHGDSVEFTCAETFTMIGLGSVFC-LSGKW-TQLPKCVATD 451
Cdd:PHA02817 100 N-GIPdskKFYYESEVSFSCKPGFVLIGTKYSVCgINSSWiPKVPICSRDN 149
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
157-209 1.02e-03

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 37.83  E-value: 1.02e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 237757318 157 EIENGFFSESFRTYALNRETSYRCKQGYVTNtgeTSGSITCLQNG-WSP-QPSCI 209
Cdd:cd00033    6 VPENGTVTGSKGSYSYGSTVTYSCNEGYTLV---GSSTITCTENGgWSPpPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
512-565 1.19e-03

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 37.89  E-value: 1.19e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 237757318   512 CPPPPQIPNTQVIETTVKYLDGEKLSVLCQDNYLTQDPEEMMC-KDGRW-QSLPHC 565
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITClENGTWsPPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
571-636 1.78e-03

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 37.44  E-value: 1.78e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 237757318 571 CSQPPTIEHGSIKLprtsekrrksiEFSSHEHGTTFSYVCDDGFRIPEENGVACYM-GKWS-TPPRCV 636
Cdd:cd00033    1 CPPPPVPENGTVTG-----------SKGSYSYGSTVTYSCNEGYTLVGSSTITCTEnGGWSpPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
157-208 2.56e-03

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 36.74  E-value: 2.56e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 237757318   157 EIENGFFSESFRTYALNRETSYRCKQGYVTNTGETsgsITCLQNG-WSP-QPSC 208
Cdd:smart00032   6 DIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSST---ITCLENGtWSPpPPTC 56
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
657-878 2.75e-03

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 40.84  E-value: 2.75e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 657 SYQHGEEVTYHCSTGFGIDGPALIkCEGGKWSDPPKCIKtdcdiLPTIENAIIRGKNKKSYRTGEQVTVRCQSPY----- 731
Cdd:PHA02954  37 SFNDKQKVTFTCDSGYYSLDPNAV-CETDKWKYENPCKK-----MCTVSDYVSELYDKPLYEVNSTITLICKDETkyfrc 110
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 732 -QMNGS----DTVTCINGRwigkpvCKDSRGKCGPPPPIDNgditSLSLPEYepfssVDYQCQKYYLLKGKKTITCRNGK 806
Cdd:PHA02954 111 eEKNGNtswnDTVTCPNAE------CQPLQLEHGSCQPVKE----KYSFGEH-----ITINCDVGYEVIGASYISCTANS 175
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 237757318 807 WSEPPTCLHACIIPEnimearkiILKWRHTKNIYSHSGEdIEFECKYGYhKARGSPpfRTKCISGTIN--YPIC 878
Cdd:PHA02954 176 WNVIPSCQQKCDIPS--------LSNGLISGSTFSIGGV-IHLSCKSGF-TLTGSP--SSTCIDGKWNpvLPIC 237
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
571-635 2.82e-03

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 36.74  E-value: 2.82e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 237757318   571 CSQPPTIEHGSIKLPRTSekrrksiefssHEHGTTFSYVCDDGFRIPEENGVACYM-GKWS-TPPRC 635
Cdd:smart00032   1 CPPPPDIENGTVTSSSGT-----------YSYGDTVTYSCDPGYTLIGSSTITCLEnGTWSpPPPTC 56
PHA02817 PHA02817
EEV Host range protein; Provisional
387-508 4.22e-03

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 39.54  E-value: 4.22e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 387 CVEEERTCGDIPELEHGSVKFSVPPYHHGDSVEFTCAET-----FTMIGLGSVFC-LSGKWT-QLPKCvatdQLEKCR-- 457
Cdd:PHA02817  17 SLCDLNKCCYPPSIKNGYIYNKKTEYNIGSNVTFFCGNNtrgvrYTLVGEKNIICeKDGKWNkEFPVC----KIIRCRfp 92
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 237757318 458 VLKSTDIEAIkPKRKEFQHNSTMYYKCRDK---QEYEHSIC-INGKWNPE-PNCIR 508
Cdd:PHA02817  93 ALQNGFVNGI-PDSKKFYYESEVSFSCKPGfvlIGTKYSVCgINSSWIPKvPICSR 147
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
55-243 5.73e-03

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 39.68  E-value: 5.73e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318  55 KYSYKCDNGF--SPPSGIfwdylrCTVQGWEPEVPCVRKC-VFHYVengQSAYWEKIYVQGQSLKVQC-----YNGYSLQ 126
Cdd:PHA02954  43 KVTFTCDSGYysLDPNAV------CETDKWKYENPCKKMCtVSDYV---SELYDKPLYEVNSTITLICkdetkYFRCEEK 113
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757318 127 NGQ----DTMTCtengwsPPPKCiriktcsvSDIEIENGFFSESFRTYALNRETSYRCKQGYvtntgETSGS--ITCLQN 200
Cdd:PHA02954 114 NGNtswnDTVTC------PNAEC--------QPLQLEHGSCQPVKEKYSFGEHITINCDVGY-----EVIGAsyISCTAN 174
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 237757318 201 GWSPQPSCIKSCERPVFENSVTKNNStwFKLNDKLDYECLIGY 243
Cdd:PHA02954 175 SWNVIPSCQQKCDIPSLSNGLISGST--FSIGGVIHLSCKSGF 215
Sushi pfam00084
Sushi repeat (SCR repeat);
571-635 6.99e-03

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 35.55  E-value: 6.99e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 237757318  571 CSQPPTIEHGSIKLPRTSekrrksiefssHEHGTTFSYVCDDGFRIPEENGVAC-YMGKWS-TPPRC 635
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNE-----------YNYGASVSYECDPGYRLVGSPTITCqEDGTWSpPFPEC 56
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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