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Conserved domains on  [gi|82654208|ref|NP_001032437|]
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zinc finger protein 830 [Rattus norvegicus]

Protein Classification

ZnF_U1 and COG4913 domain-containing protein( domain architecture ID 11751631)

protein containing domains PRP11, ZnF_U1, and COG4913

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ZnF_U1 smart00451
U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ...
 49-82 8.24e-05

U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ribonucleoprotein C and other RNA-binding proteins.


:

Pssm-ID: 197732 [Multi-domain]  Cd Length: 35  Bit Score: 39.54  E-value: 8.24e-05
                           10        20        30
                   ....*....|....*....|....*....|....
gi 82654208     49 GQLSCALCNTPVKSELLWQTHVLGKQHRERVAEL 82
Cdd:smart00451   2 GGFYCKLCNVTFTDEISVEAHLKGKKHKKNVKKR 35
COG4913 super family cl25907
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
224-362 7.26e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


The actual alignment was detected with superfamily member COG4913:

Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.82  E-value: 7.26e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 82654208  224 IEKAEIHEKVVERRENTAEALPEGFFDD---PEVDAKVRKVDAPKDQMDKEWDEFQKAMRQVNTISEAIVAEEDEEGRLD 300
Cdd:COG4913  633 LEALEAELDALQERREALQRLAEYSWDEidvASAEREIAELEAELERLDASSDDLAALEEQLEELEAELEELEEELDELK 712

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 82654208  301 RQIGEIDEQIE-CYRRVEKLRNRQDEIkNKLKEVLTIKELQKKEEENVDSDDEGELQDLLSQD 362
Cdd:COG4913  713 GEIGRLEKELEqAEEELDELQDRLEAA-EDLARLELRALLEERFAAALGDAVERELRENLEER 774
PRP11 super family cl25587
Splicing factor 3a, subunit 2 [RNA processing and modification];
18-144 8.50e-04

Splicing factor 3a, subunit 2 [RNA processing and modification];


The actual alignment was detected with superfamily member COG5246:

Pssm-ID: 227571 [Multi-domain]  Cd Length: 222  Bit Score: 40.43  E-value: 8.50e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 82654208  18 QEELRRLMKEKQRLStnrkriESPFAKYNRLGQLSCALCNTPVKSELLWQTHVLGKQHRERVAELKGAKGatqgpSAGTA 97
Cdd:COG5246  27 RSRQLLLEAYGQDLM------DDPYLSKNHTGKYVCLLCKTKHLTEMSYVKHREGKKHKENSSRRSEEKS-----SLGRE 95

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*...
gi 82654208  98 PQPTKRKTtdvESQDAKKAKASVDQVQ-PSTSASSANFEKSGKEATRV 144
Cdd:COG5246  96 NQTTHDFR---QQQKIIEAKQSLKRSGiPSYKVRSLVEPKGGRRGLGI 140
 
Name Accession Description Interval E-value
ZnF_U1 smart00451
U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ...
 49-82 8.24e-05

U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ribonucleoprotein C and other RNA-binding proteins.


Pssm-ID: 197732 [Multi-domain]  Cd Length: 35  Bit Score: 39.54  E-value: 8.24e-05
                           10        20        30
                   ....*....|....*....|....*....|....
gi 82654208     49 GQLSCALCNTPVKSELLWQTHVLGKQHRERVAEL 82
Cdd:smart00451   2 GGFYCKLCNVTFTDEISVEAHLKGKKHKKNVKKR 35
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
224-362 7.26e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.82  E-value: 7.26e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 82654208  224 IEKAEIHEKVVERRENTAEALPEGFFDD---PEVDAKVRKVDAPKDQMDKEWDEFQKAMRQVNTISEAIVAEEDEEGRLD 300
Cdd:COG4913  633 LEALEAELDALQERREALQRLAEYSWDEidvASAEREIAELEAELERLDASSDDLAALEEQLEELEAELEELEEELDELK 712

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 82654208  301 RQIGEIDEQIE-CYRRVEKLRNRQDEIkNKLKEVLTIKELQKKEEENVDSDDEGELQDLLSQD 362
Cdd:COG4913  713 GEIGRLEKELEqAEEELDELQDRLEAA-EDLARLELRALLEERFAAALGDAVERELRENLEER 774
PRP11 COG5246
Splicing factor 3a, subunit 2 [RNA processing and modification];
18-144 8.50e-04

Splicing factor 3a, subunit 2 [RNA processing and modification];


Pssm-ID: 227571 [Multi-domain]  Cd Length: 222  Bit Score: 40.43  E-value: 8.50e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 82654208  18 QEELRRLMKEKQRLStnrkriESPFAKYNRLGQLSCALCNTPVKSELLWQTHVLGKQHRERVAELKGAKGatqgpSAGTA 97
Cdd:COG5246  27 RSRQLLLEAYGQDLM------DDPYLSKNHTGKYVCLLCKTKHLTEMSYVKHREGKKHKENSSRRSEEKS-----SLGRE 95

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*...
gi 82654208  98 PQPTKRKTtdvESQDAKKAKASVDQVQ-PSTSASSANFEKSGKEATRV 144
Cdd:COG5246  96 NQTTHDFR---QQQKIIEAKQSLKRSGiPSYKVRSLVEPKGGRRGLGI 140
zf-met pfam12874
Zinc-finger of C2H2 type; This is a zinc-finger domain with the CxxCx(12)Hx(6)H motif, found ...
 51-75 1.25e-03

Zinc-finger of C2H2 type; This is a zinc-finger domain with the CxxCx(12)Hx(6)H motif, found in multiple copies in a wide range of proteins from plants to metazoans. Some member proteins, particularly those from plants, are annotated as being RNA-binding.


Pssm-ID: 463736 [Multi-domain]  Cd Length: 25  Bit Score: 35.93  E-value: 1.25e-03
                          10        20
                  ....*....|....*....|....*
gi 82654208    51 LSCALCNTPVKSELLWQTHVLGKQH 75
Cdd:pfam12874   1 FYCELCNVTFNSESQLKSHLQGKKH 25
 
Name Accession Description Interval E-value
ZnF_U1 smart00451
U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ...
 49-82 8.24e-05

U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ribonucleoprotein C and other RNA-binding proteins.


Pssm-ID: 197732 [Multi-domain]  Cd Length: 35  Bit Score: 39.54  E-value: 8.24e-05
                           10        20        30
                   ....*....|....*....|....*....|....
gi 82654208     49 GQLSCALCNTPVKSELLWQTHVLGKQHRERVAEL 82
Cdd:smart00451   2 GGFYCKLCNVTFTDEISVEAHLKGKKHKKNVKKR 35
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
224-362 7.26e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.82  E-value: 7.26e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 82654208  224 IEKAEIHEKVVERRENTAEALPEGFFDD---PEVDAKVRKVDAPKDQMDKEWDEFQKAMRQVNTISEAIVAEEDEEGRLD 300
Cdd:COG4913  633 LEALEAELDALQERREALQRLAEYSWDEidvASAEREIAELEAELERLDASSDDLAALEEQLEELEAELEELEEELDELK 712

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 82654208  301 RQIGEIDEQIE-CYRRVEKLRNRQDEIkNKLKEVLTIKELQKKEEENVDSDDEGELQDLLSQD 362
Cdd:COG4913  713 GEIGRLEKELEqAEEELDELQDRLEAA-EDLARLELRALLEERFAAALGDAVERELRENLEER 774
PRP11 COG5246
Splicing factor 3a, subunit 2 [RNA processing and modification];
18-144 8.50e-04

Splicing factor 3a, subunit 2 [RNA processing and modification];


Pssm-ID: 227571 [Multi-domain]  Cd Length: 222  Bit Score: 40.43  E-value: 8.50e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 82654208  18 QEELRRLMKEKQRLStnrkriESPFAKYNRLGQLSCALCNTPVKSELLWQTHVLGKQHRERVAELKGAKGatqgpSAGTA 97
Cdd:COG5246  27 RSRQLLLEAYGQDLM------DDPYLSKNHTGKYVCLLCKTKHLTEMSYVKHREGKKHKENSSRRSEEKS-----SLGRE 95

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*...
gi 82654208  98 PQPTKRKTtdvESQDAKKAKASVDQVQ-PSTSASSANFEKSGKEATRV 144
Cdd:COG5246  96 NQTTHDFR---QQQKIIEAKQSLKRSGiPSYKVRSLVEPKGGRRGLGI 140
zf-met pfam12874
Zinc-finger of C2H2 type; This is a zinc-finger domain with the CxxCx(12)Hx(6)H motif, found ...
 51-75 1.25e-03

Zinc-finger of C2H2 type; This is a zinc-finger domain with the CxxCx(12)Hx(6)H motif, found in multiple copies in a wide range of proteins from plants to metazoans. Some member proteins, particularly those from plants, are annotated as being RNA-binding.


Pssm-ID: 463736 [Multi-domain]  Cd Length: 25  Bit Score: 35.93  E-value: 1.25e-03
                          10        20
                  ....*....|....*....|....*
gi 82654208    51 LSCALCNTPVKSELLWQTHVLGKQH 75
Cdd:pfam12874   1 FYCELCNVTFNSESQLKSHLQGKKH 25
zf-C2H2_jaz pfam12171
Zinc-finger double-stranded RNA-binding; This domain family is found in archaea and eukaryotes, ...
 50-76 2.14e-03

Zinc-finger double-stranded RNA-binding; This domain family is found in archaea and eukaryotes, and is approximately 30 amino acids in length. The mammalian members of this group occur multiple times along the protein, joined by flexible linkers, and are referred to as JAZ - dsRNA-binding ZF protein - zinc-fingers. The JAZ proteins are expressed in all tissues tested and localize in the nucleus, particularly the nucleolus. JAZ preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids rather than DNA. In addition to binding double-stranded RNA, these zinc-fingers are required for nucleolar localization.


Pssm-ID: 432381 [Multi-domain]  Cd Length: 27  Bit Score: 35.22  E-value: 2.14e-03
                          10        20
                  ....*....|....*....|....*..
gi 82654208    50 QLSCALCNTPVKSELLWQTHVLGKQHR 76
Cdd:pfam12171   1 QFYCVLCDKYFKSENALQNHLKSKKHK 27
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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