NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|113206028|ref|NP_001037857|]
View 

mucin-1 isoform 7 precursor [Homo sapiens]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
SEA super family cl02507
SEA domain; Domain found in Sea urchin sperm protein, Enterokinase, Agrin (SEA). Proposed ...
45-85 1.68e-06

SEA domain; Domain found in Sea urchin sperm protein, Enterokinase, Agrin (SEA). Proposed function of regulating or binding carbohydrate side chains. Recently a proteolytic activity has been shown for a SEA domain.


The actual alignment was detected with superfamily member smart00200:

Pssm-ID: 445803  Cd Length: 121  Bit Score: 44.71  E-value: 1.68e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 113206028    45 ETSATQRSSVPSST--EKNAFNSSLEDPSTDYYQELQRDISEM 85
Cdd:smart00200   1 PTQSFGVSLSVLSVegENLQYSPSLEDPSSEEYQELVRDVEKL 43
 
Name Accession Description Interval E-value
SEA smart00200
Domain found in sea urchin sperm protein, enterokinase, agrin; Proposed function of regulating ...
45-85 1.68e-06

Domain found in sea urchin sperm protein, enterokinase, agrin; Proposed function of regulating or binding carbohydrate sidechains.


Pssm-ID: 214554  Cd Length: 121  Bit Score: 44.71  E-value: 1.68e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 113206028    45 ETSATQRSSVPSST--EKNAFNSSLEDPSTDYYQELQRDISEM 85
Cdd:smart00200   1 PTQSFGVSLSVLSVegENLQYSPSLEDPSSEEYQELVRDVEKL 43
 
Name Accession Description Interval E-value
SEA smart00200
Domain found in sea urchin sperm protein, enterokinase, agrin; Proposed function of regulating ...
45-85 1.68e-06

Domain found in sea urchin sperm protein, enterokinase, agrin; Proposed function of regulating or binding carbohydrate sidechains.


Pssm-ID: 214554  Cd Length: 121  Bit Score: 44.71  E-value: 1.68e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 113206028    45 ETSATQRSSVPSST--EKNAFNSSLEDPSTDYYQELQRDISEM 85
Cdd:smart00200   1 PTQSFGVSLSVLSVegENLQYSPSLEDPSSEEYQELVRDVEKL 43
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.20
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH