|
Name |
Accession |
Description |
Interval |
E-value |
| MCM |
smart00350 |
minichromosome maintenance proteins; |
133-649 |
0e+00 |
|
minichromosome maintenance proteins;
Pssm-ID: 214631 [Multi-domain] Cd Length: 509 Bit Score: 772.20 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 133 SPSSIRSLKSDTMSHLVKIPGIVIAASGVRAKATRISIQCRSCHSTLTNIaMRPGLEG---YALPRKCNTDQagrpkcpl 209
Cdd:smart00350 1 KPSSIRELRADHLGKLVRISGIVTRTSGVRPKLKRASFTCEKCGATLGPE-IQSGRETeptVCPPRECQSPT-------- 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 210 dPYFIMPDKCKCVDFQTLKLQELPDAVPHGEMPRHMQLYCDRYLCDKVVPGNRVTIMGIYSIKKFGLTSN--RGRDRVGV 287
Cdd:smart00350 72 -PFSLNHERSTFIDFQKIKLQESPEEVPVGQLPRSVDVILDGDLVDKAKPGDRVEVTGIYRNVPYGFKLNtvKGLPVFAT 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 288 GIRSAYIRVLGIQVDTDGSGRTFaGAMTPQEEEEFRRLAALPNIYELISKSIAPSIFGGTDMKKAIACLLFGGSRKRLPD 367
Cdd:smart00350 151 YIEANHVRKLDYKRSFEDSSFSV-QSLSDEEEEEIRKLSKDPDIYERLARSLAPSIYGHEDIKKAILLLLFGGVHKNLPD 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 368 GLTRRGDINLLMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSAAGLTASVMRDPSSRNFIMEGGAMVLADGGVVCIDEF 447
Cdd:smart00350 230 GMKIRGDINILLCGDPGTAKSQLLKYVEKTAPRAVYTTGKGSSAVGLTAAVTRDPETREFTLEAGALVLADNGVCCIDEF 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 448 DKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDETKG-EDNIDFMPTILSRFDMIFIVKDEHNE 526
Cdd:smart00350 310 DKMDDSDRTAIHEAMEQQTISIAKAGITTTLNARCSVLAAANPIGGRYDPKLTpEENIDLPAPILSRFDLLFVVLDEVDE 389
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 527 ERDVMLAKHVITLHV-SALTQAQAVEGEIDLAKLKKFIAYCRAKCGPRLSAEAAEKLKNRYIIMrsgaRQHERDSDRRSS 605
Cdd:smart00350 390 ERDRELAKHVVDLHRySHPEEDEAFEPPLSQEKLRKYIAYAREKIKPKLSEEAADKLVKAYVDL----RKEDSQTESRSS 465
|
490 500 510 520
....*....|....*....|....*....|....*....|....
gi 1331156041 606 IPITVRQLEAIVRIAEALSKMKLQPFATEADVEEALRLFQVSTL 649
Cdd:smart00350 466 IPITVRQLESIIRLSEAHAKMRLSDVVEEADVEEAIRLLRESII 509
|
|
| MCM5 |
cd17756 |
DNA replication licensing factor Mcm5; Mcm5 is a helicase that play an important role in ... |
334-647 |
0e+00 |
|
DNA replication licensing factor Mcm5; Mcm5 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350662 [Multi-domain] Cd Length: 317 Bit Score: 653.68 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 334 LISKSIAPSIFGGTDMKKAIACLLFGGSRKRLPDGLTRRGDINLLMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSAAG 413
Cdd:cd17756 1 IISKSIAPSIYGNEDIKKAIACLLFGGSRKRLPDGMRLRGDINVLLLGDPGTAKSQLLKFVEKVAPIGVYTSGKGSSAAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 414 LTASVMRDPSSRNFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFG 493
Cdd:cd17756 81 LTASVMRDPSTREFYLEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRTSVLAAANPVFG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 494 RWDETKGE-DNIDFMPTILSRFDMIFIVKDEHNEERDVMLAKHVITLHVSALTQAQA--VEGEIDLAKLKKFIAYCRAKC 570
Cdd:cd17756 161 RYDDLKTPgDNIDFQTTILSRFDMIFIVKDKHDEERDITIAKHVINIHASARKASQSqeNEGEIPISKLKRYIAYCRAKC 240
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1331156041 571 GPRLSAEAAEKLKNRYIIMRSGARQHERDSDRRSSIPITVRQLEAIVRIAEALSKMKLQPFATEADVEEALRLFQVS 647
Cdd:cd17756 241 APRLSEEAAEKLSNHYVTIRKDVRQNELESDNRSSIPITVRQLEAIIRISESLAKMELSPIATEKHVEEAIRLFQVS 317
|
|
| Mcm2 |
COG1241 |
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and ... |
28-721 |
0e+00 |
|
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and repair];
Pssm-ID: 440854 [Multi-domain] Cd Length: 682 Bit Score: 599.09 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 28 KSQLQRRFKEFLRQYrvgtdrtgftfKYRDELKR---HYNlGEYWIEVEMEDLASFDEELADYLYKQPAEHLQLLEEAAK 104
Cdd:COG1241 2 ESDLVDKFEEFLRRY-----------KYRDEILElaqEYP-EKRSLVVDYNDLYSFDPDLADDLLENPDEVLEAAEEALR 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 105 EVADEVTrprpagDEVLQDIQVMLKSDASPSSIRSLKSDTMSHLVKIPGIVIAASGVRAKATRISIQCRSCHSTLTNIAM 184
Cdd:COG1241 70 EIDLEPY------DVSLGDAHVRITNLPETVPIRDIRSDHIGKLISVEGIVRKATEVKPKITEAAFECPRCGTETYVPQT 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 185 RPGLEGyalPRKCntDQAGRPKcpldPYFIMPDKCKCVDFQTLKLQELPDAVPHGEMPRHMQLYCDRYLCDKVVPGNRVT 264
Cdd:COG1241 144 GEKLQE---PHEC--PGCGRQG----PFKLLPEKSEFIDAQKIRIQEPPEDLPGGQQPQSIDVILEDDLVGEVRPGDRVT 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 265 IMGIYSIKKfgltsnRGRDRVGVGIRSAYIRVLGIQVDTDGSGRTfagAMTPQEEEEFRRLAALPNIYELISKSIAPSIF 344
Cdd:COG1241 215 VTGILRIEQ------RTSGRGKSTIFDLYLEANSIEVEEKEFEEI---EITEEDEEKIKELSKDPDIYEKIIASIAPSIY 285
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 345 GGTDMKKAIACLLFGGSRKRLPDGLTRRGDINLLMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSAAGLTASVMRD-PS 423
Cdd:COG1241 286 GYEEIKEAIALQLFGGVPKVLPDGSRIRGDIHILLVGDPGTAKSQLLRYAARLAPRGVYTSGKGSTAAGLTAAAVRDdFG 365
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 424 SRNFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDETKG-ED 502
Cdd:COG1241 366 TGRWTLEAGALVLADGGLACIDELDKMREEDRSALHEAMEQQTISIAKAGIVATLNARCSVLAAANPKYGRFDPYEPiAE 445
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 503 NIDFMPTILSRFDMIFIVKDEHNEERDVMLAKHVITLH-------VSALTQAQAVEGEIDLAKLKKFIAYCRAKCGPRLS 575
Cdd:COG1241 446 QIDLPPTLLSRFDLIFVLRDKPDEERDRELARHILKVHragelleQEIEEETEEVKPEIDPDLLRKYIAYARRNVFPVLT 525
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 576 AEAAEKLKNRYIIMRSGArqherdSDRRSSIPITVRQLEAIVRIAEALSKMKLQPFATEADVEEALRLFQVSTLDAAL-- 653
Cdd:COG1241 526 EEAKDLIEDFYVDMRKKG------EDEDSPVPITARQLEALIRLAEASARMRLSDTVTEEDAERAIRLVDSCLKDVGVdp 599
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1331156041 654 -SGTL--SGVEGFTSQEDQELLSRIE---KQLKRRFaiGSQVSEHSIIQDFTKQKYPEHAIHKVLQLMLRRGEI 721
Cdd:COG1241 600 eTGKFdiDVIETGTSKSQRDKMKLIKdiiKELEEES--SGGAPIEDVIEEAEEEGIDREKAEELIEKLKRKGEI 671
|
|
| minchrom_main_MCM |
NF040949 |
minichromosome maintenance protein MCM; |
34-721 |
0e+00 |
|
minichromosome maintenance protein MCM;
Pssm-ID: 468880 [Multi-domain] Cd Length: 681 Bit Score: 597.68 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 34 RFKEFLRQYRvgtDRTGfTFKYRDELKRHYNLGEYWIEVEMEDLASFDEELADYLYKQPAEHLQLLEEAAKEVadeVTRP 113
Cdd:NF040949 4 KFKEFIRTFR---DSFG-NEKYKERIFEMIAMRKRSLVVDFNDLYMFDPELADLLIEKPDEVLPAASKALKEI---VEEE 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 114 RPAGDEVLQDIQVMLKSDASPSSIRSLKSDTMSHLVKIPGIVIAASGVRAKATRISIQCRSCHstlTNIAMRPGLEGYAL 193
Cdd:NF040949 77 DPEYAEEVAKFHVRFRNLPRTVPLRDLRSEYIGKLIAVEGIVTRTTPVKPRIVKAVFRCRDCG---CEFEWPEEEEESYE 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 194 ----PRKCntdqagrPKCPLDPYF-IMPDKCKCVDFQTLKLQELPDAVPHGEMPRHMQLYCDRYLCDKVVPGNRVTIMGI 268
Cdd:NF040949 154 ivepPTVC-------PVCGKPGSFrLLQEKSKFIDWQKIVVQERPEELPPGQLPRSIEVVLEDDLVDTARPGDRVTVTGI 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 269 YSIKKFGLTSNRGRdrvgvGIRSAYIRVLGIQVdtdgSGRTFAG-AMTPQEEEEFRRLAALPNIYELISKSIAPSIFGGT 347
Cdd:NF040949 227 LRIKPDSSLKKGSR-----PIFKNYIEANHIEV----SQKELEEvEITEEDEEKILELAKDPWIREKIIASIAPSIYGHW 297
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 348 DMKKAIACLLFGGSRKRLPDGLTRRGDINLLMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSAAGLTASVMRDPSSRNF 427
Cdd:NF040949 298 EIKEAIALLLFGGVPKVLPDGTRIRGDIHVLIVGDPGTAKSQLLQYVARLAPRAVYTSGKGSTAAGLTAAVVRDKLTGEY 377
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 428 IMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDETKG-EDNIDF 506
Cdd:NF040949 378 YLEAGALVLADGGVAVIDEIDKMREEDRSAIHEAMEQQTVSIAKAGIVATLNARASVLAAGNPKFGRYDPNRSvAENIDL 457
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 507 MPTILSRFDMIFIVKDEHNEERDVMLAKHVITLHvsalTQAQAVEGEIDLAKLKKFIAYCRAKCGPRLSAEAAEKLKNRY 586
Cdd:NF040949 458 PPTILSRFDLIFVIRDKPNEERDRRLARHILDVH----SGKEKVKPEIDPDLLKKYIAYARKYVRPKLTEEAKKLIEDFY 533
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 587 IIMRSGARQHErdsDRRSSIPITVRQLEAIVRIAEALSKMKLQPFATEADVEEALRLFQVSTLDAAL---SGTL--SGVE 661
Cdd:NF040949 534 VEMRKSSKSSE---DPDSPIPITARQLEALIRLSEAHAKMRLKDEVTAEDAERAIRLMLAFLESVGIdveTGKIdiDTIM 610
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 662 GFTSQEDQELLSRIEKQLKRRFAIGSQVSEHSIIQDFTKQKYPEHAIHKVLQLMLRRGEI 721
Cdd:NF040949 611 TGKPKSKREKMSKIVEIIKELEEEEECVKIKELIKEAEKKGIDEEKVEELISDLKRSGEI 670
|
|
| MCM |
pfam00493 |
MCM P-loop domain; |
318-540 |
2.16e-139 |
|
MCM P-loop domain;
Pssm-ID: 459830 [Multi-domain] Cd Length: 224 Bit Score: 408.46 E-value: 2.16e-139
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 318 EEEEFRRLAALPNIYELISKSIAPSIFGGTDMKKAIACLLFGGSRKRLPDGLTRRGDINLLMLGDPGTAKSQLLKFVEKC 397
Cdd:pfam00493 1 DEEEIKELAKRPDIYDKLADSIAPSIYGHEDVKKAILLQLFGGVKKILPDGTRLRGDINVLLVGDPGTAKSQLLKYVEKI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 398 SPIGVYTSGKGSSAAGLTASVMRDPSSRNFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTT 477
Cdd:pfam00493 81 APRAVYTSGKGSSAAGLTAAVVRDPVTGEFVLEAGALVLADGGVCCIDEFDKMNDEDRVALHEAMEQQTISIAKAGIVAT 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1331156041 478 LNSRCSVLAAANSVFGRWDETKG-EDNIDFMPTILSRFDMIFIVKDEHNEERDVMLAKHVITLH 540
Cdd:pfam00493 161 LNARCSILAAANPIFGRYDPKKSiAENINLPPPLLSRFDLIFVLLDKPDEEKDERLAKHIVDLH 224
|
|
| PTZ00111 |
PTZ00111 |
DNA replication licensing factor MCM4; Provisional |
71-671 |
1.12e-91 |
|
DNA replication licensing factor MCM4; Provisional
Pssm-ID: 173403 [Multi-domain] Cd Length: 915 Bit Score: 306.15 E-value: 1.12e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 71 EVEMEDLASFDEELADYLYKQPAEHLQLLEEAAKEVADEVTRPRPAGDEVLQDI---QVMLKSDASPSSIRSLKSDTMSH 147
Cdd:PTZ00111 149 EVDLMHVYSFDKVLYKLLVTFPADCIAELDKVLVKLFNELLSKHYSDLSLENNSffpRARLMNKPVSDCVGNLEPSMADS 228
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 148 LVKIPGIVIAASGVRAKATRISIQCRSchstltniAMRPGLEGYalpRKCNTDQ-----AGRPKCPL--------DPYFI 214
Cdd:PTZ00111 229 LVQFSGTVVRQTWIVPEITMACFRCRG--------QKKIGLNDY---QPCTCEHyeyviQGEVNEPLlcnecnskYTFEL 297
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 215 MPDKCKCVDFQTLKLQELPDAVPHGEMPR----------------------HMQLYCDryLCDKVVPGNRVTIMGIYSIK 272
Cdd:PTZ00111 298 NHNMCVYSTKKIVKLLQSNSSLNNPDKDGldnsvdnsglngeiymkdneviNLNLYDD--LIDSVKTGDRVTVVGILKVT 375
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 273 KFGLTSNRgrdRVGVGIRSAYIRVLGIQV-DTDGSGRTFAGAMTPQEEEEF--------RRLAALPNIYELISKSIAPSI 343
Cdd:PTZ00111 376 PIRTSTTR---RTLKSLYTYFVNVIHVKViNSTNANQPEKGLKYLGNENDFsdlqvykiLELSRNPMIYRILLDSFAPSI 452
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 344 FGGTDMKKAIACLLFGGSR-----KRLPDGLTR----RGDINLLMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSAAGL 414
Cdd:PTZ00111 453 KARNNVKIGLLCQLFSGNKnssdfNKSPDACYKvdnfRGIINVLLCGDPGTAKSQLLHYTHLLSPRSIYTSGKSSSSVGL 532
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 415 TASV-MRDPSSRNFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFG 493
Cdd:PTZ00111 533 TASIkFNESDNGRAMIQPGAVVLANGGVCCIDELDKCHNESRLSLYEVMEQQTVTIAKAGIVATLKAETAILASCNPINS 612
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 494 RWDETKGE-DNIDFMPTILSRFDMIFIVKDEHNEERD----VMLAKHVITLHVSALTQAQ---------AVEGEI----- 554
Cdd:PTZ00111 613 RYNKNKAViENINISPSLFTRFDLIYLVLDHIDQDTDqlisLSIAKDFLLPHMTGSGNDEdtydrsntmHVEDESlrsek 692
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 555 -----DLAKLKKFIAYCRAKCGPRLSAEAAEKLKNRYIIMRSGARQ----------HERDSDRR-------SSIPITVRQ 612
Cdd:PTZ00111 693 dynknDLDMLRMYIKFSKLHCFPKLSDEAKKVITREYVKMRQGNFQtsnldelehaQEDDDDDLyyqssgtRMIYVSSRM 772
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1331156041 613 LEAIVRIAEALSKMKLQPFATEADVEEALRLFQVSTLDAALSGTLSGVE------GFTSQEDQEL 671
Cdd:PTZ00111 773 ISSIIRISVSLARMRLSTVVTPADALQAVQIVKSSTFQSLVDPTTGKIDfdqlhqGITTNKMQQL 837
|
|
| MCM_N |
pfam14551 |
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins. |
32-130 |
1.13e-24 |
|
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins.
Pssm-ID: 464206 [Multi-domain] Cd Length: 95 Bit Score: 98.52 E-value: 1.13e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 32 QRRFKEFLRQYRVGTDrtgFTFKYRDELKRHYNLGEYWIEVEMEDLASFDEELADYLYKQPAEHLQLLEEAAKEVADEVt 111
Cdd:pfam14551 1 KRKFKDFLEEFREDGD---GEFKYRDQLREMIEREQRSLEVDLDDLREFDPDLAEALLENPYEYLPLFEEALKEVVKEL- 76
|
90
....*....|....*....
gi 1331156041 112 RPRPAGDEVLQDIQVMLKS 130
Cdd:pfam14551 77 SEDPDYAEEEKEFQVRFYN 95
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| MCM |
smart00350 |
minichromosome maintenance proteins; |
133-649 |
0e+00 |
|
minichromosome maintenance proteins;
Pssm-ID: 214631 [Multi-domain] Cd Length: 509 Bit Score: 772.20 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 133 SPSSIRSLKSDTMSHLVKIPGIVIAASGVRAKATRISIQCRSCHSTLTNIaMRPGLEG---YALPRKCNTDQagrpkcpl 209
Cdd:smart00350 1 KPSSIRELRADHLGKLVRISGIVTRTSGVRPKLKRASFTCEKCGATLGPE-IQSGRETeptVCPPRECQSPT-------- 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 210 dPYFIMPDKCKCVDFQTLKLQELPDAVPHGEMPRHMQLYCDRYLCDKVVPGNRVTIMGIYSIKKFGLTSN--RGRDRVGV 287
Cdd:smart00350 72 -PFSLNHERSTFIDFQKIKLQESPEEVPVGQLPRSVDVILDGDLVDKAKPGDRVEVTGIYRNVPYGFKLNtvKGLPVFAT 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 288 GIRSAYIRVLGIQVDTDGSGRTFaGAMTPQEEEEFRRLAALPNIYELISKSIAPSIFGGTDMKKAIACLLFGGSRKRLPD 367
Cdd:smart00350 151 YIEANHVRKLDYKRSFEDSSFSV-QSLSDEEEEEIRKLSKDPDIYERLARSLAPSIYGHEDIKKAILLLLFGGVHKNLPD 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 368 GLTRRGDINLLMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSAAGLTASVMRDPSSRNFIMEGGAMVLADGGVVCIDEF 447
Cdd:smart00350 230 GMKIRGDINILLCGDPGTAKSQLLKYVEKTAPRAVYTTGKGSSAVGLTAAVTRDPETREFTLEAGALVLADNGVCCIDEF 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 448 DKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDETKG-EDNIDFMPTILSRFDMIFIVKDEHNE 526
Cdd:smart00350 310 DKMDDSDRTAIHEAMEQQTISIAKAGITTTLNARCSVLAAANPIGGRYDPKLTpEENIDLPAPILSRFDLLFVVLDEVDE 389
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 527 ERDVMLAKHVITLHV-SALTQAQAVEGEIDLAKLKKFIAYCRAKCGPRLSAEAAEKLKNRYIIMrsgaRQHERDSDRRSS 605
Cdd:smart00350 390 ERDRELAKHVVDLHRySHPEEDEAFEPPLSQEKLRKYIAYAREKIKPKLSEEAADKLVKAYVDL----RKEDSQTESRSS 465
|
490 500 510 520
....*....|....*....|....*....|....*....|....
gi 1331156041 606 IPITVRQLEAIVRIAEALSKMKLQPFATEADVEEALRLFQVSTL 649
Cdd:smart00350 466 IPITVRQLESIIRLSEAHAKMRLSDVVEEADVEEAIRLLRESII 509
|
|
| MCM5 |
cd17756 |
DNA replication licensing factor Mcm5; Mcm5 is a helicase that play an important role in ... |
334-647 |
0e+00 |
|
DNA replication licensing factor Mcm5; Mcm5 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350662 [Multi-domain] Cd Length: 317 Bit Score: 653.68 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 334 LISKSIAPSIFGGTDMKKAIACLLFGGSRKRLPDGLTRRGDINLLMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSAAG 413
Cdd:cd17756 1 IISKSIAPSIYGNEDIKKAIACLLFGGSRKRLPDGMRLRGDINVLLLGDPGTAKSQLLKFVEKVAPIGVYTSGKGSSAAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 414 LTASVMRDPSSRNFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFG 493
Cdd:cd17756 81 LTASVMRDPSTREFYLEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRTSVLAAANPVFG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 494 RWDETKGE-DNIDFMPTILSRFDMIFIVKDEHNEERDVMLAKHVITLHVSALTQAQA--VEGEIDLAKLKKFIAYCRAKC 570
Cdd:cd17756 161 RYDDLKTPgDNIDFQTTILSRFDMIFIVKDKHDEERDITIAKHVINIHASARKASQSqeNEGEIPISKLKRYIAYCRAKC 240
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1331156041 571 GPRLSAEAAEKLKNRYIIMRSGARQHERDSDRRSSIPITVRQLEAIVRIAEALSKMKLQPFATEADVEEALRLFQVS 647
Cdd:cd17756 241 APRLSEEAAEKLSNHYVTIRKDVRQNELESDNRSSIPITVRQLEAIIRISESLAKMELSPIATEKHVEEAIRLFQVS 317
|
|
| Mcm2 |
COG1241 |
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and ... |
28-721 |
0e+00 |
|
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and repair];
Pssm-ID: 440854 [Multi-domain] Cd Length: 682 Bit Score: 599.09 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 28 KSQLQRRFKEFLRQYrvgtdrtgftfKYRDELKR---HYNlGEYWIEVEMEDLASFDEELADYLYKQPAEHLQLLEEAAK 104
Cdd:COG1241 2 ESDLVDKFEEFLRRY-----------KYRDEILElaqEYP-EKRSLVVDYNDLYSFDPDLADDLLENPDEVLEAAEEALR 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 105 EVADEVTrprpagDEVLQDIQVMLKSDASPSSIRSLKSDTMSHLVKIPGIVIAASGVRAKATRISIQCRSCHSTLTNIAM 184
Cdd:COG1241 70 EIDLEPY------DVSLGDAHVRITNLPETVPIRDIRSDHIGKLISVEGIVRKATEVKPKITEAAFECPRCGTETYVPQT 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 185 RPGLEGyalPRKCntDQAGRPKcpldPYFIMPDKCKCVDFQTLKLQELPDAVPHGEMPRHMQLYCDRYLCDKVVPGNRVT 264
Cdd:COG1241 144 GEKLQE---PHEC--PGCGRQG----PFKLLPEKSEFIDAQKIRIQEPPEDLPGGQQPQSIDVILEDDLVGEVRPGDRVT 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 265 IMGIYSIKKfgltsnRGRDRVGVGIRSAYIRVLGIQVDTDGSGRTfagAMTPQEEEEFRRLAALPNIYELISKSIAPSIF 344
Cdd:COG1241 215 VTGILRIEQ------RTSGRGKSTIFDLYLEANSIEVEEKEFEEI---EITEEDEEKIKELSKDPDIYEKIIASIAPSIY 285
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 345 GGTDMKKAIACLLFGGSRKRLPDGLTRRGDINLLMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSAAGLTASVMRD-PS 423
Cdd:COG1241 286 GYEEIKEAIALQLFGGVPKVLPDGSRIRGDIHILLVGDPGTAKSQLLRYAARLAPRGVYTSGKGSTAAGLTAAAVRDdFG 365
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 424 SRNFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDETKG-ED 502
Cdd:COG1241 366 TGRWTLEAGALVLADGGLACIDELDKMREEDRSALHEAMEQQTISIAKAGIVATLNARCSVLAAANPKYGRFDPYEPiAE 445
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 503 NIDFMPTILSRFDMIFIVKDEHNEERDVMLAKHVITLH-------VSALTQAQAVEGEIDLAKLKKFIAYCRAKCGPRLS 575
Cdd:COG1241 446 QIDLPPTLLSRFDLIFVLRDKPDEERDRELARHILKVHragelleQEIEEETEEVKPEIDPDLLRKYIAYARRNVFPVLT 525
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 576 AEAAEKLKNRYIIMRSGArqherdSDRRSSIPITVRQLEAIVRIAEALSKMKLQPFATEADVEEALRLFQVSTLDAAL-- 653
Cdd:COG1241 526 EEAKDLIEDFYVDMRKKG------EDEDSPVPITARQLEALIRLAEASARMRLSDTVTEEDAERAIRLVDSCLKDVGVdp 599
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1331156041 654 -SGTL--SGVEGFTSQEDQELLSRIE---KQLKRRFaiGSQVSEHSIIQDFTKQKYPEHAIHKVLQLMLRRGEI 721
Cdd:COG1241 600 eTGKFdiDVIETGTSKSQRDKMKLIKdiiKELEEES--SGGAPIEDVIEEAEEEGIDREKAEELIEKLKRKGEI 671
|
|
| minchrom_main_MCM |
NF040949 |
minichromosome maintenance protein MCM; |
34-721 |
0e+00 |
|
minichromosome maintenance protein MCM;
Pssm-ID: 468880 [Multi-domain] Cd Length: 681 Bit Score: 597.68 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 34 RFKEFLRQYRvgtDRTGfTFKYRDELKRHYNLGEYWIEVEMEDLASFDEELADYLYKQPAEHLQLLEEAAKEVadeVTRP 113
Cdd:NF040949 4 KFKEFIRTFR---DSFG-NEKYKERIFEMIAMRKRSLVVDFNDLYMFDPELADLLIEKPDEVLPAASKALKEI---VEEE 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 114 RPAGDEVLQDIQVMLKSDASPSSIRSLKSDTMSHLVKIPGIVIAASGVRAKATRISIQCRSCHstlTNIAMRPGLEGYAL 193
Cdd:NF040949 77 DPEYAEEVAKFHVRFRNLPRTVPLRDLRSEYIGKLIAVEGIVTRTTPVKPRIVKAVFRCRDCG---CEFEWPEEEEESYE 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 194 ----PRKCntdqagrPKCPLDPYF-IMPDKCKCVDFQTLKLQELPDAVPHGEMPRHMQLYCDRYLCDKVVPGNRVTIMGI 268
Cdd:NF040949 154 ivepPTVC-------PVCGKPGSFrLLQEKSKFIDWQKIVVQERPEELPPGQLPRSIEVVLEDDLVDTARPGDRVTVTGI 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 269 YSIKKFGLTSNRGRdrvgvGIRSAYIRVLGIQVdtdgSGRTFAG-AMTPQEEEEFRRLAALPNIYELISKSIAPSIFGGT 347
Cdd:NF040949 227 LRIKPDSSLKKGSR-----PIFKNYIEANHIEV----SQKELEEvEITEEDEEKILELAKDPWIREKIIASIAPSIYGHW 297
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 348 DMKKAIACLLFGGSRKRLPDGLTRRGDINLLMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSAAGLTASVMRDPSSRNF 427
Cdd:NF040949 298 EIKEAIALLLFGGVPKVLPDGTRIRGDIHVLIVGDPGTAKSQLLQYVARLAPRAVYTSGKGSTAAGLTAAVVRDKLTGEY 377
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 428 IMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDETKG-EDNIDF 506
Cdd:NF040949 378 YLEAGALVLADGGVAVIDEIDKMREEDRSAIHEAMEQQTVSIAKAGIVATLNARASVLAAGNPKFGRYDPNRSvAENIDL 457
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 507 MPTILSRFDMIFIVKDEHNEERDVMLAKHVITLHvsalTQAQAVEGEIDLAKLKKFIAYCRAKCGPRLSAEAAEKLKNRY 586
Cdd:NF040949 458 PPTILSRFDLIFVIRDKPNEERDRRLARHILDVH----SGKEKVKPEIDPDLLKKYIAYARKYVRPKLTEEAKKLIEDFY 533
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 587 IIMRSGARQHErdsDRRSSIPITVRQLEAIVRIAEALSKMKLQPFATEADVEEALRLFQVSTLDAAL---SGTL--SGVE 661
Cdd:NF040949 534 VEMRKSSKSSE---DPDSPIPITARQLEALIRLSEAHAKMRLKDEVTAEDAERAIRLMLAFLESVGIdveTGKIdiDTIM 610
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 662 GFTSQEDQELLSRIEKQLKRRFAIGSQVSEHSIIQDFTKQKYPEHAIHKVLQLMLRRGEI 721
Cdd:NF040949 611 TGKPKSKREKMSKIVEIIKELEEEEECVKIKELIKEAEKKGIDEEKVEELISDLKRSGEI 670
|
|
| MCM |
cd17706 |
MCM helicase family; MCM helicases are a family of helicases that play an important role in ... |
334-647 |
3.52e-142 |
|
MCM helicase family; MCM helicases are a family of helicases that play an important role in replication and homologous recombination repair. The heterohexameric ring-shaped Mcm2-7 complex is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases. Mcm8 and Mcm9, form a complex required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350658 [Multi-domain] Cd Length: 311 Bit Score: 419.06 E-value: 3.52e-142
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 334 LISKSIAPSIFGGTDMKKAIACLLFGGSRKRLPDGLTRRGDINLLMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSAAG 413
Cdd:cd17706 1 ILADSIAPSIYGHEDVKKAVLLQLFGGVQKILEDGTRIRGDIHILLVGDPGTAKSQILKYVLKIAPRGVYTSGKGSSGAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 414 LTASVMRDPSSRNFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFG 493
Cdd:cd17706 81 LTAAVVRDSETGEWYLEAGALVLADGGVCCIDEFDKMKELDRTALHEAMEQQTISIAKAGIVTTLNARCSILAAANPKGG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 494 RWDETKG-EDNIDFMPTILSRFDMIFIVKDEHNEERDVMLAKHVITLHVSALTQAQAVEGE----IDLAKLKKFIAYCRa 568
Cdd:cd17706 161 RYNPKLSpIENINLPSPLLSRFDLIFVIRDDPDEERDEELAEHIIDLHRGSDPEEQVKPEEdgipIDIELLRKYILYAR- 239
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1331156041 569 KCGPRLSAEAAEKLKNRYIIMRsgarqheRDSDRRSSIPITVRQLEAIVRIAEALSKMKLQPFATEADVEEALRLFQVS 647
Cdd:cd17706 240 QIHPKISEEAREKLVRWYVELR-------KESERRSTIPITARQLESVIRLAEAHAKMRLSEVVTEEDVEEAIRLVRHS 311
|
|
| MCM |
pfam00493 |
MCM P-loop domain; |
318-540 |
2.16e-139 |
|
MCM P-loop domain;
Pssm-ID: 459830 [Multi-domain] Cd Length: 224 Bit Score: 408.46 E-value: 2.16e-139
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 318 EEEEFRRLAALPNIYELISKSIAPSIFGGTDMKKAIACLLFGGSRKRLPDGLTRRGDINLLMLGDPGTAKSQLLKFVEKC 397
Cdd:pfam00493 1 DEEEIKELAKRPDIYDKLADSIAPSIYGHEDVKKAILLQLFGGVKKILPDGTRLRGDINVLLVGDPGTAKSQLLKYVEKI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 398 SPIGVYTSGKGSSAAGLTASVMRDPSSRNFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTT 477
Cdd:pfam00493 81 APRAVYTSGKGSSAAGLTAAVVRDPVTGEFVLEAGALVLADGGVCCIDEFDKMNDEDRVALHEAMEQQTISIAKAGIVAT 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1331156041 478 LNSRCSVLAAANSVFGRWDETKG-EDNIDFMPTILSRFDMIFIVKDEHNEERDVMLAKHVITLH 540
Cdd:pfam00493 161 LNARCSILAAANPIFGRYDPKKSiAENINLPPPLLSRFDLIFVLLDKPDEEKDERLAKHIVDLH 224
|
|
| MCM_arch |
cd17761 |
archaeal MCM protein; archaeal MCM proteins form a homohexameric ring homologous to the ... |
333-645 |
1.05e-131 |
|
archaeal MCM protein; archaeal MCM proteins form a homohexameric ring homologous to the eukaryotic Mcm2-7 helicase and also function as the replicative helicase at the replication fork
Pssm-ID: 350667 [Multi-domain] Cd Length: 308 Bit Score: 392.20 E-value: 1.05e-131
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 333 ELISKSIAPSIFGGTDMKKAIACLLFGGSRKRLPDGLTRRGDINLLMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSAA 412
Cdd:cd17761 1 EKIISSIAPSIYGHEDVKEAIALQLFGGVPKVLPDGTRIRGDIHILLVGDPGTAKSQLLKYVSKVAPRAVYTTGKGSTAA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 413 GLTASVMRDPSSRNFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVF 492
Cdd:cd17761 81 GLTAAVVRDEGTGEWYLEAGALVLADKGIAVVDEIDKMRKEDRSALHEAMEQQTISIAKAGIVATLNARAAVLAAANPKF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 493 GRWDETKG-EDNIDFMPTILSRFDMIFIVKDEHNEERDVMLAKHVITLHvsALTQAQAVEGEIDLAKLKKFIAYCRAKCG 571
Cdd:cd17761 161 GRFDSYRPvAEQIDLPPTLLSRFDLIFVLKDTPNEEKDRRLANHILDTH--SGGEMREIKPEIDPDLLRKYIAYARKNVR 238
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1331156041 572 PRLSAEAAEKLKNRYIIMRSGARQHErdsdrrSSIPITVRQLEAIVRIAEALSKMKLQPFATEADVEEALRLFQ 645
Cdd:cd17761 239 PVLTEEAKQLIKDFYVEMRKSGQETP------SPVPITARQLEALVRLSEASARMRLSQEVTLEDAERAIRIML 306
|
|
| MCM4 |
cd17755 |
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in ... |
334-647 |
2.60e-122 |
|
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350661 [Multi-domain] Cd Length: 309 Bit Score: 367.92 E-value: 2.60e-122
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 334 LISKSIAPSIFGGTDMKKAIACLLFGGSRKRLPDGLTR-RGDINLLMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSAA 412
Cdd:cd17755 1 RLARSIAPSIYELEDVKKGILLQLFGGTRKDFTKTGGKyRGDINILLCGDPGTSKSQLLQYVHKISPRGVYTSGKGSSAV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 413 GLTASVMRDPSSRNFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVF 492
Cdd:cd17755 81 GLTAYVTRDPDTKQLVLESGALVLSDGGICCIDEFDKMSDSTRSVLHEVMEQQTLSIAKAGIITTLNARTSILASANPIG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 493 GRWDETKG-EDNIDFMPTILSRFDMIFIVKDEHNEERDVMLAKHVITLHVSAlTQAQAVEGEIDLAKLKKFIAYCRAKCG 571
Cdd:cd17755 161 SRYNPKLTvVENIDLPPTLLSRFDLIYLVLDKVDEKYDRRLAKHLVSLYLED-TPEHIQDEVLDVEVLTDYISYAREHIH 239
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1331156041 572 PRLSAEAAEKLKNRYIIMRSGarqherDSDRRSSIPITVRQLEAIVRIAEALSKMKLQPFATEADVEEALRLFQVS 647
Cdd:cd17755 240 PKLSEEAAQELVQAYVDMRKM------GSDARKRITATPRQLESLIRLAEAHAKMRLSNVVEAEDVEEAVRLIREA 309
|
|
| MCM6 |
cd17757 |
DNA replication licensing factor Mcm6; Mcm6 is a helicase that play an important role in ... |
335-647 |
1.39e-120 |
|
DNA replication licensing factor Mcm6; Mcm6 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350663 [Multi-domain] Cd Length: 307 Bit Score: 363.61 E-value: 1.39e-120
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 335 ISKSIAPSIFGGTDMKKAIACLLFGGSRKRLPDGLTRRGDINLLMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSAAGL 414
Cdd:cd17757 2 LVRSIAPSIYGHEEVKKGILLMLLGGVHKITREGISLRGDINVCIVGDPSTAKSQFLKYVEEFSPRAVYTSGKASSAAGL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 415 TASVMRDPSSRNFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGR 494
Cdd:cd17757 82 TAAVVRDEETGDFVIEAGALMLADNGICCIDEFDKMDIKDQVAIHEAMEQQTISITKAGIQATLNARTSILAAANPVGGR 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 495 WDETKG-EDNIDFMPTILSRFDMIFIVKDEHNEERDVMLAKHVITLHVSAltqAQAVEGEIDLAKLKKFIAYCRAKCgPR 573
Cdd:cd17757 162 YDRSKSlKQNINISAPIMSRFDLFFVLLDECNEVTDYAIASHIVDLHSKR---EEAIEPPFTAEQLKRYIAYARTFK-PK 237
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1331156041 574 LSAEAAEKLKNRYIimrsGARQHERDSDRRSSIPITVRQLEAIVRIAEALSKMKLQPFATEADVEEALRLFQVS 647
Cdd:cd17757 238 LTKEAKDELVEQYK----ELRQDDASGSTRSSYRITVRQLESLIRLSEAIARLHCSDEVTPEHVEEAARLLKKS 307
|
|
| MCM2 |
cd17753 |
DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in ... |
335-643 |
3.18e-119 |
|
DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350659 [Multi-domain] Cd Length: 325 Bit Score: 360.61 E-value: 3.18e-119
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 335 ISKSIAPSIFGGTDMKKAIACLLFGGSRKRLPDGLTRRGDINLLMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSAAGL 414
Cdd:cd17753 2 IINSIAPSIYGHDDIKTAIALALFGGVAKNPGGKHRIRGDINVLLLGDPGTAKSQFLKYVEKTAHRAVFTTGQGASAVGL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 415 TASVMRDPSSRNFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGR 494
Cdd:cd17753 82 TASVRKDPVTKEWTLEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCSVIAAANPIGGR 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 495 WDETKG-EDNIDFMPTILSRFDMIFIVKDEHNEERDVMLAKHVITLHVSALTQAQAVEGEIDLAK--------------- 558
Cdd:cd17753 162 YNPTLTfAQNVNLTEPILSRFDILCVVRDTVDPEEDERLAKFVVGSHVRSHPENDEDREGEEEKNqrqrpketkvepipq 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 559 --LKKFIAYCRAKCGPRLSAEAAEKLKNRYIIMRsgarqheRDSDRRSSIPITVRQLEAIVRIAEALSKMKLQPFATEAD 636
Cdd:cd17753 242 elLRKYIHYAREKVRPKLNQMDMDKVSRVYADLR-------KESMATGSLPITVRHLESIIRISEAHAKMHLREYVSEED 314
|
....*..
gi 1331156041 637 VEEALRL 643
Cdd:cd17753 315 VDMAIRV 321
|
|
| MCM7 |
cd17758 |
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in ... |
335-647 |
3.38e-118 |
|
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350664 [Multi-domain] Cd Length: 306 Bit Score: 357.10 E-value: 3.38e-118
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 335 ISKSIAPSIFGGTDMKKAIACLLFGGSRKRlPDGLTRRGDINLLMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSAAGL 414
Cdd:cd17758 2 LAASIAPEIYGHEDVKKALLLLLVGGVDKR-GDGMKIRGDINICLMGDPGVAKSQLLKYICRIAPRSVYTTGRGSSGVGL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 415 TASVMRDPSSRNFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGR 494
Cdd:cd17758 81 TAAVMKDPVTGEMTLEGGALVLADQGICCIDEFDKMDESDRTAIHEVMEQQTISIAKAGITTTLNARTSILAAANPAYGR 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 495 WDETKG-EDNIDFMPTILSRFDMIFIVKDEHNEERDVMLAKHVITLHVSALTQAQAVEgEIDLAKLKKFIAYCRAKcGPR 573
Cdd:cd17758 161 YNPRRSpEQNINLPAALLSRFDLLFLILDKPDRDNDLRLAEHVTYVHQHNKQPDSDFE-PLDPKLLRAYIALAKRK-RPT 238
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1331156041 574 LSAEAAEKLKNRYIIMRSGARQHERDSDrrssipITVRQLEAIVRIAEALSKMKLQPFATEADVEEALRLFQVS 647
Cdd:cd17758 239 VPPALADYIVQAYVEMRQEAKRSKDFTF------TTPRTLLAILRLSQALARLRLSDSVEIDDVEEALRLMEMS 306
|
|
| MCM3 |
cd17754 |
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in ... |
334-645 |
9.31e-107 |
|
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350660 [Multi-domain] Cd Length: 299 Bit Score: 327.50 E-value: 9.31e-107
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 334 LISKSIAPSIFGGTDMKKAIACLLFGGSRKRLPDGLTRRGDINLLMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSAAG 413
Cdd:cd17754 1 LLSKSLAPSIYGHEYIKKAILLMLLGGVEKNLENGSHLRGDINILLVGDPSVAKSQLLRYVLNTAPLAIATTGRGSSGVG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 414 LTASVMRDPSSRNFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFG 493
Cdd:cd17754 81 LTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDIDRVAIHEVMEQQTVTIAKAGIHASLNARCSVLAAANPVYG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 494 RWDETKGE-DNIDFMPTILSRFDMIFIVKDEHNEERDVMLAKHVITLHVSaltqaqavegeidLAKLKKFIAYCRAKCGP 572
Cdd:cd17754 161 RYDVYKTPmENIGLPDSLLSRFDLLFIVLDDIDEERDRSISEHVLRMHRY-------------IKFLRKYIHYAKERIKP 227
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1331156041 573 RLSAEAAEKLKNRYIIMRSGARQherDSDRRSSIPITVRQLEAIVRIAEALSKMKLQPFATEADVEEALRLFQ 645
Cdd:cd17754 228 KLTQEAAEYIAEEYADLRNDDNT---KTDKARTSPITARTLETLIRLATAHAKARLSKTVDKVDAEVALNLLR 297
|
|
| PTZ00111 |
PTZ00111 |
DNA replication licensing factor MCM4; Provisional |
71-671 |
1.12e-91 |
|
DNA replication licensing factor MCM4; Provisional
Pssm-ID: 173403 [Multi-domain] Cd Length: 915 Bit Score: 306.15 E-value: 1.12e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 71 EVEMEDLASFDEELADYLYKQPAEHLQLLEEAAKEVADEVTRPRPAGDEVLQDI---QVMLKSDASPSSIRSLKSDTMSH 147
Cdd:PTZ00111 149 EVDLMHVYSFDKVLYKLLVTFPADCIAELDKVLVKLFNELLSKHYSDLSLENNSffpRARLMNKPVSDCVGNLEPSMADS 228
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 148 LVKIPGIVIAASGVRAKATRISIQCRSchstltniAMRPGLEGYalpRKCNTDQ-----AGRPKCPL--------DPYFI 214
Cdd:PTZ00111 229 LVQFSGTVVRQTWIVPEITMACFRCRG--------QKKIGLNDY---QPCTCEHyeyviQGEVNEPLlcnecnskYTFEL 297
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 215 MPDKCKCVDFQTLKLQELPDAVPHGEMPR----------------------HMQLYCDryLCDKVVPGNRVTIMGIYSIK 272
Cdd:PTZ00111 298 NHNMCVYSTKKIVKLLQSNSSLNNPDKDGldnsvdnsglngeiymkdneviNLNLYDD--LIDSVKTGDRVTVVGILKVT 375
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 273 KFGLTSNRgrdRVGVGIRSAYIRVLGIQV-DTDGSGRTFAGAMTPQEEEEF--------RRLAALPNIYELISKSIAPSI 343
Cdd:PTZ00111 376 PIRTSTTR---RTLKSLYTYFVNVIHVKViNSTNANQPEKGLKYLGNENDFsdlqvykiLELSRNPMIYRILLDSFAPSI 452
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 344 FGGTDMKKAIACLLFGGSR-----KRLPDGLTR----RGDINLLMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSAAGL 414
Cdd:PTZ00111 453 KARNNVKIGLLCQLFSGNKnssdfNKSPDACYKvdnfRGIINVLLCGDPGTAKSQLLHYTHLLSPRSIYTSGKSSSSVGL 532
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 415 TASV-MRDPSSRNFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFG 493
Cdd:PTZ00111 533 TASIkFNESDNGRAMIQPGAVVLANGGVCCIDELDKCHNESRLSLYEVMEQQTVTIAKAGIVATLKAETAILASCNPINS 612
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 494 RWDETKGE-DNIDFMPTILSRFDMIFIVKDEHNEERD----VMLAKHVITLHVSALTQAQ---------AVEGEI----- 554
Cdd:PTZ00111 613 RYNKNKAViENINISPSLFTRFDLIYLVLDHIDQDTDqlisLSIAKDFLLPHMTGSGNDEdtydrsntmHVEDESlrsek 692
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 555 -----DLAKLKKFIAYCRAKCGPRLSAEAAEKLKNRYIIMRSGARQ----------HERDSDRR-------SSIPITVRQ 612
Cdd:PTZ00111 693 dynknDLDMLRMYIKFSKLHCFPKLSDEAKKVITREYVKMRQGNFQtsnldelehaQEDDDDDLyyqssgtRMIYVSSRM 772
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1331156041 613 LEAIVRIAEALSKMKLQPFATEADVEEALRLFQVSTLDAALSGTLSGVE------GFTSQEDQEL 671
Cdd:PTZ00111 773 ISSIIRISVSLARMRLSTVVTPADALQAVQIVKSSTFQSLVDPTTGKIDfdqlhqGITTNKMQQL 837
|
|
| MCM8 |
cd17759 |
DNA helicase Mcm8; Mcm8 plays an important role homologous recombination repair. It forms a ... |
334-647 |
4.63e-78 |
|
DNA helicase Mcm8; Mcm8 plays an important role homologous recombination repair. It forms a complex with Mcm9 that is required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350665 [Multi-domain] Cd Length: 289 Bit Score: 252.07 E-value: 4.63e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 334 LISKSIAPSIFGGTDMKKAIACLLFGGSRKRLPDG--LTRRGDINLLMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSA 411
Cdd:cd17759 1 LIVNSLCPAIYGHELVKAGLLLSLFGGKQKYADDKnrIPIRGDPHVLIVGDPGLGKSQMLQAACNIAPRGVYVCGNTTTT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 412 AGLTASVMRDPSSRNFIMEGGAMVLADGGVVCIDEFDKMrEDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSV 491
Cdd:cd17759 81 SGLTVTLTKDGRSGDFALEAGALVLGDQGICGIDEFDKM-GSQHQALLEAMEQQSVSLAKAGVVCSLPARTSVIAAANPV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 492 FGRWDETKG-EDNIDFMPTILSRFDMIFIVKDEHNEERDVMLAKHVITlhvsaltqaqavegeidlakLKKFIAYCRAKC 570
Cdd:cd17759 160 GGHYNKGKTvSENLKMGPALLSRFDLVFILLDTPSEEHDHLLSEHHQL--------------------LRKYISYARQYV 219
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1331156041 571 GPRLSAEAAEKLKNRYIIMRSgarqherDSDRRSSIPITVRQLEAIVRIAEALSKMKLQPFATEADVEEALRLFQVS 647
Cdd:cd17759 220 NPVLSKDASEALQEFYLELRK-------QNQLADSSPITTRQLESLIRLTEARARLELREEATKEDAEDVIEIMKES 289
|
|
| MCM9 |
cd17760 |
DNA helicase Mcm9; Mcm9 plays an important role homologous recombination repair. It forms a ... |
334-647 |
8.55e-71 |
|
DNA helicase Mcm9; Mcm9 plays an important role homologous recombination repair. It forms a complex with Mcm8 that is required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350666 [Multi-domain] Cd Length: 299 Bit Score: 233.21 E-value: 8.55e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 334 LISKSIAPSIFGGTDMKKAIACLLFGGSRKRLPDGLTRRGDINLLMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSAAG 413
Cdd:cd17760 1 EILASLCPQVFGLYNVKLAVAMVLAGGVQRIDASGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTAGIGSTSAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 414 LTASVMRDpsSRNFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVfG 493
Cdd:cd17760 81 LTVTAVKD--GGEWNLEAGALVLADGGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPK-G 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 494 RWDETKG-EDNIDFMPTILSRFDMIFIVKDEHNEERDVMLAKHVITlhvsalTQAQAVEGEI--DLAKLKKFIAYCRaKC 570
Cdd:cd17760 158 QYDPNESiSVNIALASPLLSRFDLVLVLLDTKNEDWDRIISSFILE------NKGEPSKSSKlwSMEKMRTYFCLIK-NL 230
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1331156041 571 GPRLSAEAAEKLKNRYiimrsgarQHERDSDRRSSIPITVRQLEAIVRIAEALSKMKLQPFATEADVEEALRLFQVS 647
Cdd:cd17760 231 RPVLSDEANAILLRYY--------QLQRQSDCRNAARTTIRMLESLIRLAEAHARLMFRETVTEEDAITVVSVMESS 299
|
|
| MCM_OB |
pfam17207 |
MCM OB domain; This family contains an OB-fold found within MCM proteins. This domain contains ... |
136-271 |
3.96e-52 |
|
MCM OB domain; This family contains an OB-fold found within MCM proteins. This domain contains an insertion at the zinc binding motif.
Pssm-ID: 465381 [Multi-domain] Cd Length: 126 Bit Score: 176.52 E-value: 3.96e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 136 SIRSLKSDTMSHLVKIPGIVIAASGVRAKATRISIQCRSCHSTLTNIamrpglegYALPRKCNtdqagRPKCP-LDPYFI 214
Cdd:pfam17207 1 SIRDLRSEHIGKLVSVSGIVTRTSEVRPKLKKATFTCRKCGHTVGVK--------ITEPTKCP-----NPECGnKDPFKL 67
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 1331156041 215 MPDKCKCVDFQTLKLQELPDAVPHGEMPRHMQLYCDRYLCDKVVPGNRVTIMGIYSI 271
Cdd:pfam17207 68 VHEKSKFVDFQKIKIQESPEEVPAGELPRSLDVILDDDLVDRVKPGDRVTVTGIYRV 124
|
|
| MCM_lid |
pfam17855 |
MCM AAA-lid domain; This entry represents the AAA-lid domain found in MCM proteins. |
558-648 |
1.99e-33 |
|
MCM AAA-lid domain; This entry represents the AAA-lid domain found in MCM proteins.
Pssm-ID: 465534 [Multi-domain] Cd Length: 86 Bit Score: 123.04 E-value: 1.99e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 558 KLKKFIAYCRAKCGPRLSAEAAEKLKNRYIIMRSgarqheRDSDRRSSIPITVRQLEAIVRIAEALSKMKLQPFATEADV 637
Cdd:pfam17855 2 LLRKYIAYAREKIKPKLSEEAREKLVDAYVELRK------ESTGSGSSIPITVRQLESLIRLSEAHAKMRLSEIVTEEDV 75
|
90
....*....|.
gi 1331156041 638 EEALRLFQVST 648
Cdd:pfam17855 76 EEAIRLLKESL 86
|
|
| MCM_N |
pfam14551 |
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins. |
32-130 |
1.13e-24 |
|
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins.
Pssm-ID: 464206 [Multi-domain] Cd Length: 95 Bit Score: 98.52 E-value: 1.13e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 32 QRRFKEFLRQYRVGTDrtgFTFKYRDELKRHYNLGEYWIEVEMEDLASFDEELADYLYKQPAEHLQLLEEAAKEVADEVt 111
Cdd:pfam14551 1 KRKFKDFLEEFREDGD---GEFKYRDQLREMIEREQRSLEVDLDDLREFDPDLAEALLENPYEYLPLFEEALKEVVKEL- 76
|
90
....*....|....*....
gi 1331156041 112 RPRPAGDEVLQDIQVMLKS 130
Cdd:pfam14551 77 SEDPDYAEEEKEFQVRFYN 95
|
|
| AAA |
cd00009 |
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ... |
376-520 |
1.35e-03 |
|
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.
Pssm-ID: 99707 [Multi-domain] Cd Length: 151 Bit Score: 39.82 E-value: 1.35e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1331156041 376 NLLMLGDPGTAKSQLLKFVEKCSPIG----VYTSgkgssAAGLTASVMRDPSSRNFIMEG--GAMVLADGGVVCIDEFDK 449
Cdd:cd00009 21 NLLLYGPPGTGKTTLARAIANELFRPgapfLYLN-----ASDLLEGLVVAELFGHFLVRLlfELAEKAKPGVLFIDEIDS 95
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1331156041 450 MREDDRVAIHEAMEQQTisiakagITTTLNSRCSVLAAANSvfgrwdetkgEDNIDFMPTILSRFDMIFIV 520
Cdd:cd00009 96 LSRGAQNALLRVLETLN-------DLRIDRENVRVIGATNR----------PLLGDLDRALYDRLDIRIVI 149
|
|
| AAA_5 |
pfam07728 |
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not ... |
376-449 |
4.11e-03 |
|
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.
Pssm-ID: 400191 [Multi-domain] Cd Length: 135 Bit Score: 38.04 E-value: 4.11e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1331156041 376 NLLMLGDPGTAKSQL---LKFVEKCSPIGVYTSGKGSSAAGLTASvmRDPSSRNFIMEGGAMVLA--DGGVVCIDEFDK 449
Cdd:pfam07728 1 GVLLVGPPGTGKTELaerLAAALSNRPVFYVQLTRDTTEEDLFGR--RNIDPGGASWVDGPLVRAarEGEIAVLDEINR 77
|
|
| |
