|
Name |
Accession |
Description |
Interval |
E-value |
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
4-344 |
3.84e-74 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 235.96 E-value: 3.84e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124517674 4 SGSALRVCADHRGGINWLSLSPDGQRLLTGSEDGTARLWSTVDGQCCALLQGHESYVTfchledEAAF--------TCSA 75
Cdd:COG2319 67 AGALLATLLGHTAAVLSVAFSPDGRLLASASADGTVRLWDLATGLLLRTLTGHTGAVR------SVAFspdgktlaSGSA 140
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124517674 76 DCTIRRWDVRTGQCLQVYRGHTSIVNRILVAND--QLFSSSYDRTARVWTVDKGQVSQEFRGHRNCVLTLAYSApedlpq 153
Cdd:COG2319 141 DGTVRLWDLATGKLLRTLTGHSGAVTSVAFSPDgkLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSP------ 214
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124517674 154 dpcmeaamGGGLLVTGSSDDTAKVWQVASGCCHQTLRGHTGAVLCLVLHVSSHTAFTGSTDATVRAWDILSGEQLRVFRE 233
Cdd:COG2319 215 --------DGKLLASGSADGTVRLWDLATGKLLRTLTGHSGSVRSVAFSPDGRLLASGSADGTVRLWDLATGELLRTLTG 286
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124517674 234 HQGSVICLELT--DRLLYSGSADRTVKCWLADTGERVLTFPAHRHSVSALKYHA--GTLFTGSGDACARAFDAQSGVLQR 309
Cdd:COG2319 287 HSGGVNSVAFSpdGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPdgKTLASGSDDGTVRLWDLATGELLR 366
|
330 340 350
....*....|....*....|....*....|....*..
gi 124517674 310 VFRGHTFVINCLQVH--GQVLYTASHDGALRLWDVRG 344
Cdd:COG2319 367 TLTGHTGAVTSVAFSpdGRTLASGSADGTVRLWDLAT 403
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
8-301 |
1.79e-64 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 207.19 E-value: 1.79e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124517674 8 LRVCADHRGGINWLSLSPDGQRLLTGSEDGTARLWSTVDGQCCALLQGHESYVTFCHL--EDEAAFTCSADCTIRRWDVR 85
Cdd:cd00200 2 RRTLKGHTGGVTCVAFSPDGKLLATGSGDGTIKVWDLETGELLRTLKGHTGPVRDVAAsaDGTYLASGSSDKTIRLWDLE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124517674 86 TGQCLQVYRGHTSIVNRILVANDQ--LFSSSYDRTARVWTVDKGQVSQEFRGHRNCVLTLAYSapedlpqdPCmeaamgG 163
Cdd:cd00200 82 TGECVRTLTGHTSYVSSVAFSPDGriLSSSSRDKTIKVWDVETGKCLTTLRGHTDWVNSVAFS--------PD------G 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124517674 164 GLLVTGSSDDTAKVWQVASGCCHQTLRGHTGAVLCLVLHVSSHTAFTGSTDATVRAWDILSGEQLRVFREHQGSVICL-- 241
Cdd:cd00200 148 TFVASSSQDGTIKLWDLRTGKCVATLTGHTGEVNSVAFSPDGEKLLSSSSDGTIKLWDLSTGKCLGTLRGHENGVNSVaf 227
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 124517674 242 ELTDRLLYSGSADRTVKCWLADTGERVLTFPAHRHSVSALKYH--AGTLFTGSGDACARAFD 301
Cdd:cd00200 228 SPDGYLLASGSEDGTIRVWDLRTGECVQTLSGHTNSVTSLAWSpdGKRLASGSADGTIRIWD 289
|
|
| PLN00181 |
PLN00181 |
protein SPA1-RELATED; Provisional |
109-260 |
3.97e-08 |
|
protein SPA1-RELATED; Provisional
Pssm-ID: 177776 [Multi-domain] Cd Length: 793 Bit Score: 55.09 E-value: 3.97e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124517674 109 QLFSSSYDRTARVWTVDKGQVSQEFRGHRNCVLTLAYSApedlpQDPCmeaamgggLLVTGSSDDTAKVWQVASGCCHQT 188
Cdd:PLN00181 547 QVASSNFEGVVQVWDVARSQLVTEMKEHEKRVWSIDYSS-----ADPT--------LLASGSDDGSVKLWSINQGVSIGT 613
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 124517674 189 LRghTGAVLCLVLHVSS---HTAFtGSTDATVRAWDILSGE-QLRVFREHQGSVICLELTD-RLLYSGSADRTVKCW 260
Cdd:PLN00181 614 IK--TKANICCVQFPSEsgrSLAF-GSADHKVYYYDLRNPKlPLCTMIGHSKTVSYVRFVDsSTLVSSSTDNTLKLW 687
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
4-43 |
6.89e-07 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 45.38 E-value: 6.89e-07
10 20 30 40
....*....|....*....|....*....|....*....|
gi 124517674 4 SGSALRVCADHRGGINWLSLSPDGQRLLTGSEDGTARLWS 43
Cdd:smart00320 1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
|
|
| WD40 |
pfam00400 |
WD domain, G-beta repeat; |
5-43 |
7.52e-06 |
|
WD domain, G-beta repeat;
Pssm-ID: 459801 [Multi-domain] Cd Length: 39 Bit Score: 42.33 E-value: 7.52e-06
10 20 30
....*....|....*....|....*....|....*....
gi 124517674 5 GSALRVCADHRGGINWLSLSPDGQRLLTGSEDGTARLWS 43
Cdd:pfam00400 1 GKLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
|
|
|
|
Name |
Accession |
Description |
Interval |
E-value |
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
4-344 |
3.84e-74 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 235.96 E-value: 3.84e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124517674 4 SGSALRVCADHRGGINWLSLSPDGQRLLTGSEDGTARLWSTVDGQCCALLQGHESYVTfchledEAAF--------TCSA 75
Cdd:COG2319 67 AGALLATLLGHTAAVLSVAFSPDGRLLASASADGTVRLWDLATGLLLRTLTGHTGAVR------SVAFspdgktlaSGSA 140
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124517674 76 DCTIRRWDVRTGQCLQVYRGHTSIVNRILVAND--QLFSSSYDRTARVWTVDKGQVSQEFRGHRNCVLTLAYSApedlpq 153
Cdd:COG2319 141 DGTVRLWDLATGKLLRTLTGHSGAVTSVAFSPDgkLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSP------ 214
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124517674 154 dpcmeaamGGGLLVTGSSDDTAKVWQVASGCCHQTLRGHTGAVLCLVLHVSSHTAFTGSTDATVRAWDILSGEQLRVFRE 233
Cdd:COG2319 215 --------DGKLLASGSADGTVRLWDLATGKLLRTLTGHSGSVRSVAFSPDGRLLASGSADGTVRLWDLATGELLRTLTG 286
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124517674 234 HQGSVICLELT--DRLLYSGSADRTVKCWLADTGERVLTFPAHRHSVSALKYHA--GTLFTGSGDACARAFDAQSGVLQR 309
Cdd:COG2319 287 HSGGVNSVAFSpdGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPdgKTLASGSDDGTVRLWDLATGELLR 366
|
330 340 350
....*....|....*....|....*....|....*..
gi 124517674 310 VFRGHTFVINCLQVH--GQVLYTASHDGALRLWDVRG 344
Cdd:COG2319 367 TLTGHTGAVTSVAFSpdGRTLASGSADGTVRLWDLAT 403
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
3-362 |
2.51e-67 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 218.24 E-value: 2.51e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124517674 3 SSGSALRVCADHRGGINWLSLSPDGQRLLTGSEDGTARLWSTVDGQCCALLQGHESYVTFCHL--EDEAAFTCSADCTIR 80
Cdd:COG2319 24 ALGALLLLLLGLAAAVASLAASPDGARLAAGAGDLTLLLLDAAAGALLATLLGHTAAVLSVAFspDGRLLASASADGTVR 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124517674 81 RWDVRTGQCLQVYRGHTSIVNRILVAND--QLFSSSYDRTARVWTVDKGQVSQEFRGHRNCVLTLAYSApedlpqdpcme 158
Cdd:COG2319 104 LWDLATGLLLRTLTGHTGAVRSVAFSPDgkTLASGSADGTVRLWDLATGKLLRTLTGHSGAVTSVAFSP----------- 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124517674 159 aamGGGLLVTGSSDDTAKVWQVASGCCHQTLRGHTGAVLCLVLHVSSHTAFTGSTDATVRAWDILSGEQLRVFREHQGSV 238
Cdd:COG2319 173 ---DGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKLLASGSADGTVRLWDLATGKLLRTLTGHSGSV 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124517674 239 ICLELT--DRLLYSGSADRTVKCWLADTGERVLTFPAHRHSVSALKYHAG--TLFTGSGDACARAFDAQSGVLQRVFRGH 314
Cdd:COG2319 250 RSVAFSpdGRLLASGSADGTVRLWDLATGELLRTLTGHSGGVNSVAFSPDgkLLASGSDDGTVRLWDLATGKLLRTLTGH 329
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|
gi 124517674 315 TFVINCLQVH--GQVLYTASHDGALRLWDVRGLQSVPPLPRRPAAKRSLS 362
Cdd:COG2319 330 TGAVRSVAFSpdGKTLASGSDDGTVRLWDLATGELLRTLTGHTGAVTSVA 379
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
8-301 |
1.79e-64 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 207.19 E-value: 1.79e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124517674 8 LRVCADHRGGINWLSLSPDGQRLLTGSEDGTARLWSTVDGQCCALLQGHESYVTFCHL--EDEAAFTCSADCTIRRWDVR 85
Cdd:cd00200 2 RRTLKGHTGGVTCVAFSPDGKLLATGSGDGTIKVWDLETGELLRTLKGHTGPVRDVAAsaDGTYLASGSSDKTIRLWDLE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124517674 86 TGQCLQVYRGHTSIVNRILVANDQ--LFSSSYDRTARVWTVDKGQVSQEFRGHRNCVLTLAYSapedlpqdPCmeaamgG 163
Cdd:cd00200 82 TGECVRTLTGHTSYVSSVAFSPDGriLSSSSRDKTIKVWDVETGKCLTTLRGHTDWVNSVAFS--------PD------G 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124517674 164 GLLVTGSSDDTAKVWQVASGCCHQTLRGHTGAVLCLVLHVSSHTAFTGSTDATVRAWDILSGEQLRVFREHQGSVICL-- 241
Cdd:cd00200 148 TFVASSSQDGTIKLWDLRTGKCVATLTGHTGEVNSVAFSPDGEKLLSSSSDGTIKLWDLSTGKCLGTLRGHENGVNSVaf 227
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 124517674 242 ELTDRLLYSGSADRTVKCWLADTGERVLTFPAHRHSVSALKYH--AGTLFTGSGDACARAFD 301
Cdd:cd00200 228 SPDGYLLASGSEDGTIRVWDLRTGECVQTLSGHTNSVTSLAWSpdGKRLASGSADGTIRIWD 289
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
3-260 |
7.76e-60 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 195.25 E-value: 7.76e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124517674 3 SSGSALRVCADHRGGINWLSLSPDGQRLLTGSEDGTARLWSTVDGQCCALLQGHESYVTFCHL--EDEAAFTCSADCTIR 80
Cdd:cd00200 39 ETGELLRTLKGHTGPVRDVAASADGTYLASGSSDKTIRLWDLETGECVRTLTGHTSYVSSVAFspDGRILSSSSRDKTIK 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124517674 81 RWDVRTGQCLQVYRGHTSIVN--RILVANDQLFSSSYDRTARVWTVDKGQVSQEFRGHRNCVLTLAYSApedlpqdpcme 158
Cdd:cd00200 119 VWDVETGKCLTTLRGHTDWVNsvAFSPDGTFVASSSQDGTIKLWDLRTGKCVATLTGHTGEVNSVAFSP----------- 187
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124517674 159 aamGGGLLVTGSSDDTAKVWQVASGCCHQTLRGHTGAVLCLVLHVSSHTAFTGSTDATVRAWDILSGEQLRVFREHQGSV 238
Cdd:cd00200 188 ---DGEKLLSSSSDGTIKLWDLSTGKCLGTLRGHENGVNSVAFSPDGYLLASGSEDGTIRVWDLRTGECVQTLSGHTNSV 264
|
250 260
....*....|....*....|....
gi 124517674 239 ICLELTD--RLLYSGSADRTVKCW 260
Cdd:cd00200 265 TSLAWSPdgKRLASGSADGTIRIW 288
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
3-260 |
5.94e-59 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 196.29 E-value: 5.94e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124517674 3 SSGSALRVCADHRGGINWLSLSPDGQRLLTGSEDGTARLWSTVDGQCCALLQGHESYVTfchledEAAF--------TCS 74
Cdd:COG2319 150 ATGKLLRTLTGHSGAVTSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVR------SVAFspdgkllaSGS 223
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124517674 75 ADCTIRRWDVRTGQCLQVYRGHTSIVNRILVAND--QLFSSSYDRTARVWTVDKGQVSQEFRGHRNCVLTLAYSApedlp 152
Cdd:COG2319 224 ADGTVRLWDLATGKLLRTLTGHSGSVRSVAFSPDgrLLASGSADGTVRLWDLATGELLRTLTGHSGGVNSVAFSP----- 298
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124517674 153 qdpcmeaamGGGLLVTGSSDDTAKVWQVASGCCHQTLRGHTGAVLCLVLHVSSHTAFTGSTDATVRAWDILSGEQLRVFR 232
Cdd:COG2319 299 ---------DGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKTLASGSDDGTVRLWDLATGELLRTLT 369
|
250 260 270
....*....|....*....|....*....|
gi 124517674 233 EHQGSVICLELT--DRLLYSGSADRTVKCW 260
Cdd:COG2319 370 GHTGAVTSVAFSpdGRTLASGSADGTVRLW 399
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
22-366 |
1.24e-56 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 190.51 E-value: 1.24e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124517674 22 SLSPDGQRLLTGSEDGTARLWSTVDGQCCALLQGHESYVT--FCHLEDEAAFTCSADCTIRRWDVRTGQCLQVYRGHTSI 99
Cdd:COG2319 1 ALSADGAALAAASADLALALLAAALGALLLLLLGLAAAVAslAASPDGARLAAGAGDLTLLLLDAAAGALLATLLGHTAA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124517674 100 VNRILVAND--QLFSSSYDRTARVWTVDKGQVSQEFRGHRNCVLTLAYSApedlpqdpcmeaamGGGLLVTGSSDDTAKV 177
Cdd:COG2319 81 VLSVAFSPDgrLLASASADGTVRLWDLATGLLLRTLTGHTGAVRSVAFSP--------------DGKTLASGSADGTVRL 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124517674 178 WQVASGCCHQTLRGHTGAVLCLVLHVSSHTAFTGSTDATVRAWDILSGEQLRVFREHQGSVICLELT--DRLLYSGSADR 255
Cdd:COG2319 147 WDLATGKLLRTLTGHSGAVTSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSpdGKLLASGSADG 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124517674 256 TVKCWLADTGERVLTFPAHRHSVSALKYHAG--TLFTGSGDACARAFDAQSGVLQRVFRGHTFVINCLQVH--GQVLYTA 331
Cdd:COG2319 227 TVRLWDLATGKLLRTLTGHSGSVRSVAFSPDgrLLASGSADGTVRLWDLATGELLRTLTGHSGGVNSVAFSpdGKLLASG 306
|
330 340 350
....*....|....*....|....*....|....*
gi 124517674 332 SHDGALRLWDVRGLQSVPPLPRRPAAKRSLSrlFS 366
Cdd:COG2319 307 SDDGTVRLWDLATGKLLRTLTGHTGAVRSVA--FS 339
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
89-352 |
5.34e-54 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 179.84 E-value: 5.34e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124517674 89 CLQVYRGHTSIVNRILVANDQ--LFSSSYDRTARVWTVDKGQVSQEFRGHRNCVLTLAYSApedlpqdpcmeaamGGGLL 166
Cdd:cd00200 1 LRRTLKGHTGGVTCVAFSPDGklLATGSGDGTIKVWDLETGELLRTLKGHTGPVRDVAASA--------------DGTYL 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124517674 167 VTGSSDDTAKVWQVASGCCHQTLRGHTGAVLCLVLHVSSHTAFTGSTDATVRAWDILSGEQLRVFREHQGSVICLEL--T 244
Cdd:cd00200 67 ASGSSDKTIRLWDLETGECVRTLTGHTSYVSSVAFSPDGRILSSSSRDKTIKVWDVETGKCLTTLRGHTDWVNSVAFspD 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124517674 245 DRLLYSGSADRTVKCWLADTGERVLTFPAHRHSVSALKYHA--GTLFTGSGDACARAFDAQSGVLQRVFRGHTFVINCLQ 322
Cdd:cd00200 147 GTFVASSSQDGTIKLWDLRTGKCVATLTGHTGEVNSVAFSPdgEKLLSSSSDGTIKLWDLSTGKCLGTLRGHENGVNSVA 226
|
250 260 270
....*....|....*....|....*....|..
gi 124517674 323 VH--GQVLYTASHDGALRLWDVRGLQSVPPLP 352
Cdd:cd00200 227 FSpdGYLLASGSEDGTIRVWDLRTGECVQTLS 258
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
3-221 |
2.83e-47 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 162.50 E-value: 2.83e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124517674 3 SSGSALRVCADHRGGINWLSLSPDGQRLLTGSEDGTARLWSTVDGQCCALLQGHESYVTFC--HLEDEAAFTCSADCTIR 80
Cdd:cd00200 81 ETGECVRTLTGHTSYVSSVAFSPDGRILSSSSRDKTIKVWDVETGKCLTTLRGHTDWVNSVafSPDGTFVASSSQDGTIK 160
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124517674 81 RWDVRTGQCLQVYRGHTSIVNRILVAND--QLFSSSYDRTARVWTVDKGQVSQEFRGHRNCVLTLAYSApedlpqdpcme 158
Cdd:cd00200 161 LWDLRTGKCVATLTGHTGEVNSVAFSPDgeKLLSSSSDGTIKLWDLSTGKCLGTLRGHENGVNSVAFSP----------- 229
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 124517674 159 aamGGGLLVTGSSDDTAKVWQVASGCCHQTLRGHTGAVLCLVLHVSSHTAFTGSTDATVRAWD 221
Cdd:cd00200 230 ---DGYLLASGSEDGTIRVWDLRTGECVQTLSGHTNSVTSLAWSPDGKRLASGSADGTIRIWD 289
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
130-373 |
8.85e-43 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 150.56 E-value: 8.85e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124517674 130 SQEFRGHRNCVLTLAYSApedlpqdpcmeaamGGGLLVTGSSDDTAKVWQVASGCCHQTLRGHTGAVLCLVLHVSSHTAF 209
Cdd:cd00200 2 RRTLKGHTGGVTCVAFSP--------------DGKLLATGSGDGTIKVWDLETGELLRTLKGHTGPVRDVAASADGTYLA 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124517674 210 TGSTDATVRAWDILSGEQLRVFREHQGSVICLELT--DRLLYSGSADRTVKCWLADTGERVLTFPAHRHSVSALKYH--A 285
Cdd:cd00200 68 SGSSDKTIRLWDLETGECVRTLTGHTSYVSSVAFSpdGRILSSSSRDKTIKVWDVETGKCLTTLRGHTDWVNSVAFSpdG 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124517674 286 GTLFTGSGDACARAFDAQSGVLQRVFRGHTFVINCLQVH--GQVLYTASHDGALRLWDVRGLQSVPPLPRRPAAKRSLSR 363
Cdd:cd00200 148 TFVASSSQDGTIKLWDLRTGKCVATLTGHTGEVNSVAFSpdGEKLLSSSSDGTIKLWDLSTGKCLGTLRGHENGVNSVAF 227
|
250
....*....|
gi 124517674 364 LFSNKVACAA 373
Cdd:cd00200 228 SPDGYLLASG 237
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
2-122 |
6.18e-28 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 110.89 E-value: 6.18e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124517674 2 GSSGSALRVCADHRGGINWLSLSPDGQRLLTGSEDGTARLWSTVDGQCCALLQGHESYVTFC--HLEDEAAFTCSADCTI 79
Cdd:cd00200 164 LRTGKCVATLTGHTGEVNSVAFSPDGEKLLSSSSDGTIKLWDLSTGKCLGTLRGHENGVNSVafSPDGYLLASGSEDGTI 243
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 124517674 80 RRWDVRTGQCLQVYRGHTSIVNRILVAND--QLFSSSYDRTARVW 122
Cdd:cd00200 244 RVWDLRTGECVQTLSGHTNSVTSLAWSPDgkRLASGSADGTIRIW 288
|
|
| PLN00181 |
PLN00181 |
protein SPA1-RELATED; Provisional |
109-260 |
3.97e-08 |
|
protein SPA1-RELATED; Provisional
Pssm-ID: 177776 [Multi-domain] Cd Length: 793 Bit Score: 55.09 E-value: 3.97e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124517674 109 QLFSSSYDRTARVWTVDKGQVSQEFRGHRNCVLTLAYSApedlpQDPCmeaamgggLLVTGSSDDTAKVWQVASGCCHQT 188
Cdd:PLN00181 547 QVASSNFEGVVQVWDVARSQLVTEMKEHEKRVWSIDYSS-----ADPT--------LLASGSDDGSVKLWSINQGVSIGT 613
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 124517674 189 LRghTGAVLCLVLHVSS---HTAFtGSTDATVRAWDILSGE-QLRVFREHQGSVICLELTD-RLLYSGSADRTVKCW 260
Cdd:PLN00181 614 IK--TKANICCVQFPSEsgrSLAF-GSADHKVYYYDLRNPKlPLCTMIGHSKTVSYVRFVDsSTLVSSSTDNTLKLW 687
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
4-43 |
6.89e-07 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 45.38 E-value: 6.89e-07
10 20 30 40
....*....|....*....|....*....|....*....|
gi 124517674 4 SGSALRVCADHRGGINWLSLSPDGQRLLTGSEDGTARLWS 43
Cdd:smart00320 1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
|
|
| WD40 |
pfam00400 |
WD domain, G-beta repeat; |
5-43 |
7.52e-06 |
|
WD domain, G-beta repeat;
Pssm-ID: 459801 [Multi-domain] Cd Length: 39 Bit Score: 42.33 E-value: 7.52e-06
10 20 30
....*....|....*....|....*....|....*....
gi 124517674 5 GSALRVCADHRGGINWLSLSPDGQRLLTGSEDGTARLWS 43
Cdd:pfam00400 1 GKLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
182-221 |
9.19e-06 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 42.30 E-value: 9.19e-06
10 20 30 40
....*....|....*....|....*....|....*....|
gi 124517674 182 SGCCHQTLRGHTGAVLCLVLHVSSHTAFTGSTDATVRAWD 221
Cdd:smart00320 1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
|
|
| WD40 |
pfam00400 |
WD domain, G-beta repeat; |
183-221 |
1.08e-05 |
|
WD domain, G-beta repeat;
Pssm-ID: 459801 [Multi-domain] Cd Length: 39 Bit Score: 41.95 E-value: 1.08e-05
10 20 30
....*....|....*....|....*....|....*....
gi 124517674 183 GCCHQTLRGHTGAVLCLVLHVSSHTAFTGSTDATVRAWD 221
Cdd:pfam00400 1 GKLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
|
|
| PLN00181 |
PLN00181 |
protein SPA1-RELATED; Provisional |
197-342 |
1.81e-05 |
|
protein SPA1-RELATED; Provisional
Pssm-ID: 177776 [Multi-domain] Cd Length: 793 Bit Score: 46.62 E-value: 1.81e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124517674 197 LCLVLHVSSHTAfTGSTDATVRAWDILSGEQLRVFREHQGSVICLELTD---RLLYSGSADRTVKCWLADTGERVLTFPA 273
Cdd:PLN00181 538 ICWNSYIKSQVA-SSNFEGVVQVWDVARSQLVTEMKEHEKRVWSIDYSSadpTLLASGSDDGSVKLWSINQGVSIGTIKT 616
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 124517674 274 hRHSVSALKYHAGT---LFTGSGDACARAFDAQSGVLQR-VFRGHTFVINCLQ-VHGQVLYTASHDGALRLWDV 342
Cdd:PLN00181 617 -KANICCVQFPSESgrsLAFGSADHKVYYYDLRNPKLPLcTMIGHSKTVSYVRfVDSSTLVSSSTDNTLKLWDL 689
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
304-341 |
3.78e-05 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 40.37 E-value: 3.78e-05
10 20 30 40
....*....|....*....|....*....|....*....|
gi 124517674 304 SGVLQRVFRGHTFVINCLQVH--GQVLYTASHDGALRLWD 341
Cdd:smart00320 1 SGELLKTLKGHTGPVTSVAFSpdGKYLASGSDDGTIKLWD 40
|
|
| WD40 |
pfam00400 |
WD domain, G-beta repeat; |
305-341 |
1.34e-04 |
|
WD domain, G-beta repeat;
Pssm-ID: 459801 [Multi-domain] Cd Length: 39 Bit Score: 38.87 E-value: 1.34e-04
10 20 30
....*....|....*....|....*....|....*....
gi 124517674 305 GVLQRVFRGHTFVINCLQVH--GQVLYTASHDGALRLWD 341
Cdd:pfam00400 1 GKLLKTLEGHTGSVTSLAFSpdGKLLASGSDDGTVKVWD 39
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
86-122 |
2.55e-04 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 38.06 E-value: 2.55e-04
10 20 30
....*....|....*....|....*....|....*....
gi 124517674 86 TGQCLQVYRGHTSIVNRILVAND--QLFSSSYDRTARVW 122
Cdd:smart00320 1 SGELLKTLKGHTGPVTSVAFSPDgkYLASGSDDGTIKLW 39
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
224-260 |
3.45e-04 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 37.68 E-value: 3.45e-04
10 20 30
....*....|....*....|....*....|....*....
gi 124517674 224 SGEQLRVFREHQGSVICLEL--TDRLLYSGSADRTVKCW 260
Cdd:smart00320 1 SGELLKTLKGHTGPVTSVAFspDGKYLASGSDDGTIKLW 39
|
|
| PTZ00421 |
PTZ00421 |
coronin; Provisional |
5-282 |
5.58e-04 |
|
coronin; Provisional
Pssm-ID: 173611 [Multi-domain] Cd Length: 493 Bit Score: 41.80 E-value: 5.58e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124517674 5 GSALRVCADHRGGINWLSLSpdgqrlltgsedGTARLWSTVDGQCCA---LLQGHESY---VTFCHLEDEAAFTCSADCT 78
Cdd:PTZ00421 32 CSNTIACNDRFIAVPWQQLG------------STAVLKHTDYGKLASnppILLGQEGPiidVAFNPFDPQKLFTASEDGT 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124517674 79 IRRWDVR----TGQC------LQVYRGHTSIVNRILVANDQLFSSSYDRTARVWTVDKGQVSQEFRGHRNCVLTLAYSap 148
Cdd:PTZ00421 100 IMGWGIPeeglTQNIsdpivhLQGHTKKVGIVSFHPSAMNVLASAGADMVVNVWDVERGKAVEVIKCHSDQITSLEWN-- 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124517674 149 edlpqdpcmeaaMGGGLLVTGSSDDTAKVWQ------VASGCCHQTLRGHTgAVLCLVLHVSSHTAFTGSTDATVRAWDI 222
Cdd:PTZ00421 178 ------------LDGSLLCTTSKDKKLNIIDprdgtiVSSVEAHASAKSQR-CLWAKRKDLIITLGCSKSQQRQIMLWDT 244
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 124517674 223 LSGEQ-LRVFREHQGSVICLELTDR---LLYSGS-ADRTVKCW-LADTGervLTFPAHRHSVSALK 282
Cdd:PTZ00421 245 RKMASpYSTVDLDQSSALFIPFFDEdtnLLYIGSkGEGNIRCFeLMNER---LTFCSSYSSVEPHK 307
|
|
| WD40 |
pfam00400 |
WD domain, G-beta repeat; |
225-260 |
1.03e-03 |
|
WD domain, G-beta repeat;
Pssm-ID: 459801 [Multi-domain] Cd Length: 39 Bit Score: 36.55 E-value: 1.03e-03
10 20 30
....*....|....*....|....*....|....*...
gi 124517674 225 GEQLRVFREHQGSVICLEL--TDRLLYSGSADRTVKCW 260
Cdd:pfam00400 1 GKLLKTLEGHTGSVTSLAFspDGKLLASGSDDGTVKVW 38
|
|
| WD40 |
pfam00400 |
WD domain, G-beta repeat; |
87-122 |
1.34e-03 |
|
WD domain, G-beta repeat;
Pssm-ID: 459801 [Multi-domain] Cd Length: 39 Bit Score: 36.17 E-value: 1.34e-03
10 20 30
....*....|....*....|....*....|....*...
gi 124517674 87 GQCLQVYRGHTSIVNRILVANDQ--LFSSSYDRTARVW 122
Cdd:pfam00400 1 GKLLKTLEGHTGSVTSLAFSPDGklLASGSDDGTVKVW 38
|
|
| PQQ_2 |
pfam13360 |
PQQ-like domain; This domain contains several repeats of the PQQ repeat. |
214-337 |
6.16e-03 |
|
PQQ-like domain; This domain contains several repeats of the PQQ repeat.
Pssm-ID: 433144 [Multi-domain] Cd Length: 233 Bit Score: 37.77 E-value: 6.16e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124517674 214 DATVRAWDILSGEQLRVFREHQGSVICLELTDRLLYSGSADRTVKCWLADTGERVLTFPAHRHSVSALKYHAGTLFTGSG 293
Cdd:pfam13360 2 DGVVTALDAATGAELWRVDLETGLGGGVAVDGGRLFVATGGGQLVALDAATGKLLWRQTLSGEVLGAPLVAGGRVFVVAG 81
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 124517674 294 DACARAFDAQSGVLQRVFRGHTFVINCLQ-----VHGQVLYTASHDGAL 337
Cdd:pfam13360 82 DGSLIALDAADGRRLWSYQRSGEPLALRSsgspaVVGDTVVAGFSSGKL 130
|
|
|