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Conserved domains on  [gi|157820141|ref|NP_001101497|]
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kelch domain-containing protein 1 isoform 2 [Rattus norvegicus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
10-297 1.38e-23

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 97.15  E-value: 1.38e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820141  10 AEERSGHCAVVDGHFLYVWGGYVSIEdnevylPNDEIWTYDVDSGLWKmhlmegELPP----SMSGSCGACINGRLYVFG 85
Cdd:COG3055   10 PTPRSEAAAALLDGKVYVAGGLSGGS------ASNSFEVYDPATNTWS------ELAPlpgpPRHHAAAVAQDGKLYVFG 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820141  86 GYDDK----GYSNRLYFVDLRTRDgtyiWEKITKFegqpPTPRDKLSCWVYKDRLIYFGGYGYRRHSelqecfdvhdasw 161
Cdd:COG3055   78 GFTGAnpssTPLNDVYVYDPATNT----WTKLAPM----PTPRGGATALLLDGKIYVVGGWDDGGNV------------- 136

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820141 162 eeqifwgwhNDVHVFDTKTRTWSQpeikGGVPPQPRAAHSCAVLGN-KGYVFGGRvlqtrmNDLHYLNldtwVWSgrisv 240
Cdd:COG3055  137 ---------AWVEVYDPATGTWTQ----LAPLPTPRDHLAAAVLPDgKILVIGGR------NGSGFSN----TWT----- 188

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 157820141 241 NGESPKHRSWHTLTAIADDKLFLFGGLSAdniPLSDGWIHNIITNCWKQLRHLPYTR 297
Cdd:COG3055  189 TLAPLPTARAGHAAAVLGGKILVFGGESG---FSDEVEAYDPATNTWTALGELPTPR 242
 
Name Accession Description Interval E-value
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
10-297 1.38e-23

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 97.15  E-value: 1.38e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820141  10 AEERSGHCAVVDGHFLYVWGGYVSIEdnevylPNDEIWTYDVDSGLWKmhlmegELPP----SMSGSCGACINGRLYVFG 85
Cdd:COG3055   10 PTPRSEAAAALLDGKVYVAGGLSGGS------ASNSFEVYDPATNTWS------ELAPlpgpPRHHAAAVAQDGKLYVFG 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820141  86 GYDDK----GYSNRLYFVDLRTRDgtyiWEKITKFegqpPTPRDKLSCWVYKDRLIYFGGYGYRRHSelqecfdvhdasw 161
Cdd:COG3055   78 GFTGAnpssTPLNDVYVYDPATNT----WTKLAPM----PTPRGGATALLLDGKIYVVGGWDDGGNV------------- 136

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820141 162 eeqifwgwhNDVHVFDTKTRTWSQpeikGGVPPQPRAAHSCAVLGN-KGYVFGGRvlqtrmNDLHYLNldtwVWSgrisv 240
Cdd:COG3055  137 ---------AWVEVYDPATGTWTQ----LAPLPTPRDHLAAAVLPDgKILVIGGR------NGSGFSN----TWT----- 188

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 157820141 241 NGESPKHRSWHTLTAIADDKLFLFGGLSAdniPLSDGWIHNIITNCWKQLRHLPYTR 297
Cdd:COG3055  189 TLAPLPTARAGHAAAVLGGKILVFGGESG---FSDEVEAYDPATNTWTALGELPTPR 242
PLN02193 PLN02193
nitrile-specifier protein
 13-282 7.45e-14

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 71.53  E-value: 7.45e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820141  13 RSGHCAVVDGHFLYVWGGYvsiednevYLPNDEI----WTYDVDSGLWKMHLMEGELPP-SMSGSCGACINGRLYVFGGY 87
Cdd:PLN02193 166 RCSHGIAQVGNKIYSFGGE--------FTPNQPIdkhlYVFDLETRTWSISPATGDVPHlSCLGVRMVSIGSTLYVFGGR 237

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820141  88 DDKGYSNRLYFVDLRTRDgtyiWEKITKFEgQPPTPRDKLSCWVYKDRLIYFGGYGYRRHSELQECFDVHDASW------ 161
Cdd:PLN02193 238 DASRQYNGFYSFDTTTNE----WKLLTPVE-EGPTPRSFHSMAADEENVYVFGGVSATARLKTLDSYNIVDKKWfhcstp 312

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820141 162 -----------------EEQIFWGWH----NDVHVFDTKTRTWSQPEiKGGVPPQPRAAHSCAVLGNKGYVFGGRVlqtR 220
Cdd:PLN02193 313 gdsfsirggaglevvqgKVWVVYGFNgcevDDVHYYDPVQDKWTQVE-TFGVRPSERSVFASAAVGKHIVIFGGEI---A 388

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 157820141 221 MNDLHYLN----------LDT----WVWSGRISVNGESPKHRSWH-TLTAIADDK--LFLFGGLSADNIPLSDGWIHNI 282
Cdd:PLN02193 389 MDPLAHVGpgqltdgtfaLDTetlqWERLDKFGEEEETPSSRGWTaSTTGTIDGKkgLVMHGGKAPTNDRFDDLFFYGI 467
Kelch_4 pfam13418
Galactose oxidase, central domain;
247-295 1.43e-08

Galactose oxidase, central domain;


Pssm-ID: 433191 [Multi-domain]  Cd Length: 49  Bit Score: 49.92  E-value: 1.43e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 157820141  247 HRSWHTLTAIADDKLFLFGGLSADNIPLSDGWIHNIITNCWKQLRHLPY 295
Cdd:pfam13418   1 PRAYHTSTSIPDDTIYLFGGEGEDGTLLSDLWVFDLSTNEWTRLGSLPS 49
F_box_assoc_1 TIGR01640
F-box protein interaction domain; This model describes a large family of plant domains, with ...
 32-136 1.82e-03

F-box protein interaction domain; This model describes a large family of plant domains, with several hundred members in Arabidopsis thaliana. Most examples are found C-terminal to an F-box (pfam00646), a 60 amino acid motif involved in ubiquitination of target proteins to mark them for degradation. Two-hybid experiments support the idea that most members are interchangeable F-box subunits of SCF E3 complexes. Some members have two copies of this domain.


Pssm-ID: 273726 [Multi-domain]  Cd Length: 230  Bit Score: 38.88  E-value: 1.82e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820141   32 VSIEDNEVYLPNDEIWTYDVDSGLWKMhlMEGELPPSMSGSCGACINGRLYvFGGYDDKGysNRLYFV---DLRTrdgty 108
Cdd:TIGR01640  58 LCFSDRSGNRNQSEHQVYTLGSNSWRT--IECSPPHHPLKSRGVCINGVLY-YLAYTLKT--NPDYFIvsfDVSS----- 127

                          90       100       110
                  ....*....|....*....|....*....|..
gi 157820141  109 iwEKITKFeGQPPTPR----DKLSCWVYKDRL 136
Cdd:TIGR01640 128 --ERFKEF-IPLPCGNsdsvDYLSLINYKGKL 156
 
Name Accession Description Interval E-value
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
10-297 1.38e-23

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 97.15  E-value: 1.38e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820141  10 AEERSGHCAVVDGHFLYVWGGYVSIEdnevylPNDEIWTYDVDSGLWKmhlmegELPP----SMSGSCGACINGRLYVFG 85
Cdd:COG3055   10 PTPRSEAAAALLDGKVYVAGGLSGGS------ASNSFEVYDPATNTWS------ELAPlpgpPRHHAAAVAQDGKLYVFG 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820141  86 GYDDK----GYSNRLYFVDLRTRDgtyiWEKITKFegqpPTPRDKLSCWVYKDRLIYFGGYGYRRHSelqecfdvhdasw 161
Cdd:COG3055   78 GFTGAnpssTPLNDVYVYDPATNT----WTKLAPM----PTPRGGATALLLDGKIYVVGGWDDGGNV------------- 136

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820141 162 eeqifwgwhNDVHVFDTKTRTWSQpeikGGVPPQPRAAHSCAVLGN-KGYVFGGRvlqtrmNDLHYLNldtwVWSgrisv 240
Cdd:COG3055  137 ---------AWVEVYDPATGTWTQ----LAPLPTPRDHLAAAVLPDgKILVIGGR------NGSGFSN----TWT----- 188

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 157820141 241 NGESPKHRSWHTLTAIADDKLFLFGGLSAdniPLSDGWIHNIITNCWKQLRHLPYTR 297
Cdd:COG3055  189 TLAPLPTARAGHAAAVLGGKILVFGGESG---FSDEVEAYDPATNTWTALGELPTPR 242
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
182-297 2.98e-15

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 74.04  E-value: 2.98e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820141 182 TWSQpeikGGVPPQPRAAHSCAVLGNKGYVFGGRVLQTRMNDLHYLNLDTWVWsgriSVNGESPKHRSWHTLTAIADDKL 261
Cdd:COG3055    2 TWSS----LPDLPTPRSEAAAALLDGKVYVAGGLSGGSASNSFEVYDPATNTW----SELAPLPGPPRHHAAAVAQDGKL 73

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 157820141 262 FLFGGLSADN---IPLSDGWIHNIITNCWKQLRHLPYTR 297
Cdd:COG3055   74 YVFGGFTGANpssTPLNDVYVYDPATNTWTKLAPMPTPR 112
PLN02193 PLN02193
nitrile-specifier protein
 13-282 7.45e-14

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 71.53  E-value: 7.45e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820141  13 RSGHCAVVDGHFLYVWGGYvsiednevYLPNDEI----WTYDVDSGLWKMHLMEGELPP-SMSGSCGACINGRLYVFGGY 87
Cdd:PLN02193 166 RCSHGIAQVGNKIYSFGGE--------FTPNQPIdkhlYVFDLETRTWSISPATGDVPHlSCLGVRMVSIGSTLYVFGGR 237

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820141  88 DDKGYSNRLYFVDLRTRDgtyiWEKITKFEgQPPTPRDKLSCWVYKDRLIYFGGYGYRRHSELQECFDVHDASW------ 161
Cdd:PLN02193 238 DASRQYNGFYSFDTTTNE----WKLLTPVE-EGPTPRSFHSMAADEENVYVFGGVSATARLKTLDSYNIVDKKWfhcstp 312

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820141 162 -----------------EEQIFWGWH----NDVHVFDTKTRTWSQPEiKGGVPPQPRAAHSCAVLGNKGYVFGGRVlqtR 220
Cdd:PLN02193 313 gdsfsirggaglevvqgKVWVVYGFNgcevDDVHYYDPVQDKWTQVE-TFGVRPSERSVFASAAVGKHIVIFGGEI---A 388

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 157820141 221 MNDLHYLN----------LDT----WVWSGRISVNGESPKHRSWH-TLTAIADDK--LFLFGGLSADNIPLSDGWIHNI 282
Cdd:PLN02193 389 MDPLAHVGpgqltdgtfaLDTetlqWERLDKFGEEEETPSSRGWTaSTTGTIDGKkgLVMHGGKAPTNDRFDDLFFYGI 467
PLN02153 PLN02153
epithiospecifier protein
 110-268 1.99e-09

epithiospecifier protein


Pssm-ID: 177814 [Multi-domain]  Cd Length: 341  Bit Score: 57.69  E-value: 1.99e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820141 110 WEKITKFEGQPPTPRDKLSCWVYKDRLIYFGGygyrrhsELQEcfdvhdaswEEQIfwgwHNDVHVFDTKTRTWSQPEIK 189
Cdd:PLN02153   9 WIKVEQKGGKGPGPRCSHGIAVVGDKLYSFGG-------ELKP---------NEHI----DKDLYVFDFNTHTWSIAPAN 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820141 190 GGVPPQPRAAHSCAVLGNKGYVFGGRVLQTRMNDLHylNLDT----WVWSGRISVNGeSPKHRSWHTLTAiADDKLFLFG 265
Cdd:PLN02153  69 GDVPRISCLGVRMVAVGTKLYIFGGRDEKREFSDFY--SYDTvkneWTFLTKLDEEG-GPEARTFHSMAS-DENHVYVFG 144


                 ...
gi 157820141 266 GLS 268
Cdd:PLN02153 145 GVS 147
PLN02153 PLN02153
epithiospecifier protein
 183-293 2.12e-09

epithiospecifier protein


Pssm-ID: 177814 [Multi-domain]  Cd Length: 341  Bit Score: 57.69  E-value: 2.12e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820141 183 WSQPEIKGGVPPQPRAAHSCAVLGNKGYVFGGRVLQTRM--NDLHYLNLDTWVWSgRISVNGESPKHRSWHTLTAIADDK 260
Cdd:PLN02153   9 WIKVEQKGGKGPGPRCSHGIAVVGDKLYSFGGELKPNEHidKDLYVFDFNTHTWS-IAPANGDVPRISCLGVRMVAVGTK 87

                         90       100       110
                 ....*....|....*....|....*....|...
gi 157820141 261 LFLFGGLSAdNIPLSDGWIHNIITNCWKQLRHL 293
Cdd:PLN02153  88 LYIFGGRDE-KREFSDFYSYDTVKNEWTFLTKL 119
Kelch_4 pfam13418
Galactose oxidase, central domain;
247-295 1.43e-08

Galactose oxidase, central domain;


Pssm-ID: 433191 [Multi-domain]  Cd Length: 49  Bit Score: 49.92  E-value: 1.43e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 157820141  247 HRSWHTLTAIADDKLFLFGGLSADNIPLSDGWIHNIITNCWKQLRHLPY 295
Cdd:pfam13418   1 PRAYHTSTSIPDDTIYLFGGEGEDGTLLSDLWVFDLSTNEWTRLGSLPS 49
PHA03098 PHA03098
kelch-like protein; Provisional
 13-162 1.22e-07

kelch-like protein; Provisional


Pssm-ID: 222983 [Multi-domain]  Cd Length: 534  Bit Score: 52.46  E-value: 1.22e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820141  13 RSGHCAVVDGHFLYVWGGyvsIEDNEVYLPNDEIwtYDVDSGLWKMHLMegeLPPSMSGSCGACINGRLYVFGGY---DD 89
Cdd:PHA03098 380 RYNPCVVNVNNLIYVIGG---ISKNDELLKTVEC--FSLNTNKWSKGSP---LPISHYGGCAIYHDGKIYVIGGIsyiDN 451

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 157820141  90 KGYSNRLYFVDLRTrdGTYIWEKITKFegqpptPRDKLSCWVYKDRLIYFGGYGYRRHSELQECFDVHDASWE 162
Cdd:PHA03098 452 IKVYNIVESYNPVT--NKWTELSSLNF------PRINASLCIFNNKIYVVGGDKYEYYINEIEVYDDKTNTWT 516
PLN02153 PLN02153
epithiospecifier protein
 13-255 8.75e-07

epithiospecifier protein


Pssm-ID: 177814 [Multi-domain]  Cd Length: 341  Bit Score: 49.60  E-value: 8.75e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820141  13 RSGHCAVVDGHFLYVWGGYVSiednevylPNDEI----WTYDVDSGLWKMHLMEGElPPSMS--GSCGACINGRLYVFGG 86
Cdd:PLN02153  23 RCSHGIAVVGDKLYSFGGELK--------PNEHIdkdlYVFDFNTHTWSIAPANGD-VPRISclGVRMVAVGTKLYIFGG 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820141  87 YDDKGYSNRLYFVDLRTRDgtyiWEKITKFEGQP-PTPRDKLSCWVYKDRLIYFGGYGY-------RRHSELqECFDVHD 158
Cdd:PLN02153  94 RDEKREFSDFYSYDTVKNE----WTFLTKLDEEGgPEARTFHSMASDENHVYVFGGVSKgglmktpERFRTI-EAYNIAD 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820141 159 ASWEE-------------------------------QIFWGWHND-----VHVFDTKTRTWSQPEIKGGvPPQPRAAHSC 202
Cdd:PLN02153 169 GKWVQlpdpgenfekrggagfavvqgkiwvvygfatSILPGGKSDyesnaVQFFDPASGKWTEVETTGA-KPSARSVFAH 247

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 157820141 203 AVLGNKGYVFGGRVLQ---------TRMNDLHYLNLDTWVWSgRISVNGESPKHRSWHTLTA 255
Cdd:PLN02153 248 AVVGKYIIIFGGEVWPdlkghlgpgTLSNEGYALDTETLVWE-KLGECGEPAMPRGWTAYTT 308
Kelch_5 pfam13854
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 13-54 1.70e-06

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 433528 [Multi-domain]  Cd Length: 41  Bit Score: 44.09  E-value: 1.70e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 157820141   13 RSGHCAVVDGHFLYVWGGYVSIEDNevylPNDEIWTYDVDSG 54
Cdd:pfam13854   4 RYGHCAVTVGDYIYLYGGYTGGEGQ----PSDDVYVLSLPTF 41
PRK14131 PRK14131
N-acetylneuraminate epimerase;
64-214 3.61e-06

N-acetylneuraminate epimerase;


Pssm-ID: 237617 [Multi-domain]  Cd Length: 376  Bit Score: 47.70  E-value: 3.61e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820141  64 ELPPSMSGSCGACINGRLYV-FGGYDDKGYSnrlyfVDLRTRDGTyiWEKITKFEGQPptpRDKLSCWVYKDRLIYFGGY 142
Cdd:PRK14131  24 DLPVPFKNGTGAIDNNTVYVgLGSAGTSWYK-----LDLNAPSKG--WTKIAAFPGGP---REQAVAAFIDGKLYVFGGI 93

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 157820141 143 GYRRHSElqecfdvhdaswEEQIFwgwhNDVHVFDTKTRTWSQPEIKggvPPQPRAAHSCAVL-GNKGYVFGG 214
Cdd:PRK14131  94 GKTNSEG------------SPQVF----DDVYKYDPKTNSWQKLDTR---SPVGLAGHVAVSLhNGKAYITGG 147
PLN02193 PLN02193
nitrile-specifier protein
 54-278 5.53e-06

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 47.64  E-value: 5.53e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820141  54 GLWKMHLMEGELPPSMSGSCGACINGRLYVFGG--YDDKGYSNRLYFVDLRTRdgtyIWEkITKFEGQPPTprdkLSCwv 131
Cdd:PLN02193 151 GKWIKVEQKGEGPGLRCSHGIAQVGNKIYSFGGefTPNQPIDKHLYVFDLETR----TWS-ISPATGDVPH----LSC-- 219

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820141 132 YKDRLIYFGGYGYrrhselqeCFDVHDASWEeqifwgwHNDVHVFDTKTRTWS--QPEIKGgvpPQPRAAHSCAVLGNKG 209
Cdd:PLN02193 220 LGVRMVSIGSTLY--------VFGGRDASRQ-------YNGFYSFDTTTNEWKllTPVEEG---PTPRSFHSMAADEENV 281

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 157820141 210 YVFGGRVLQTRMNDLHYLNLDTWVWSgRISVNGESPKHRSWHTLTAIADDKLFLFG--GLSADNI----PLSDGW 278
Cdd:PLN02193 282 YVFGGVSATARLKTLDSYNIVDKKWF-HCSTPGDSFSIRGGAGLEVVQGKVWVVYGfnGCEVDDVhyydPVQDKW 355
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
11-141 3.28e-05

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 44.38  E-value: 3.28e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820141  11 EERSGHCAVVDGHFLYVWGGYVSIEdnevylPNDEIWTYDVDSGLWKMhlmEGELPPSMSGSCGACI-NGRLYVFGGYDD 89
Cdd:COG3055  110 TPRGGATALLLDGKIYVVGGWDDGG------NVAWVEVYDPATGTWTQ---LAPLPTPRDHLAAAVLpDGKILVIGGRNG 180

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820141  90 KGYSN----------------------RLYFVDLRTR--DGTYI-------WEKItkfeGQPPTPRDKLSCWVYKDRLIY 138
Cdd:COG3055  181 SGFSNtwttlaplptaraghaaavlggKILVFGGESGfsDEVEAydpatntWTAL----GELPTPRHGHAAVLTDGKVYV 256


                 ...
gi 157820141 139 FGG 141
Cdd:COG3055  257 IGG 259
PHA03098 PHA03098
kelch-like protein; Provisional
 170-295 3.47e-05

kelch-like protein; Provisional


Pssm-ID: 222983 [Multi-domain]  Cd Length: 534  Bit Score: 45.14  E-value: 3.47e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820141 170 HNDVHVFDTKTRTW-SQPEIKggvppQPRAAHSCAVLGNKGYVFGGRVLQTRMNDLHYLNLDTWVWsgRISVNGESPKHR 248
Cdd:PHA03098 310 VNSVVSYDTKTKSWnKVPELI-----YPRKNPGVTVFNNRIYVIGGIYNSISLNTVESWKPGESKW--REEPPLIFPRYN 382

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 157820141 249 SwhtLTAIADDKLFLFGGLSADNIPLSDGWIHNIITNCWKQLRHLPY 295
Cdd:PHA03098 383 P---CVVNVNNLIYVIGGISKNDELLKTVECFSLNTNKWSKGSPLPI 426
Kelch_1 pfam01344
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 196-235 2.69e-04

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 396078 [Multi-domain]  Cd Length: 46  Bit Score: 37.98  E-value: 2.69e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 157820141  196 PRAAHSCAVLGNKGYVFGGRVLQTRMNDLHYLNLDTWVWS 235
Cdd:pfam01344   1 RRSGAGVVVVGGKIYVIGGFDGNQSLNSVEVYDPETNTWS 40
Kelch_6 pfam13964
Kelch motif;
254-297 6.50e-04

Kelch motif;


Pssm-ID: 404790 [Multi-domain]  Cd Length: 50  Bit Score: 36.93  E-value: 6.50e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 157820141  254 TAIADDKLFLFGGLSADNIPLSDGWIHNIITNCWKQLRHLPYTR 297
Cdd:pfam13964   7 VVSVGGYIYVFGGYTNASPALNKLEVYNPLTKSWEELPPLPTPR 50
Kelch_3 pfam13415
Galactose oxidase, central domain;
206-256 1.06e-03

Galactose oxidase, central domain;


Pssm-ID: 433188 [Multi-domain]  Cd Length: 49  Bit Score: 36.50  E-value: 1.06e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 157820141  206 GNKGYVFGGRVL--QTRMNDLHYLNLDTWVWsgriSVNGESPKHRSWHTLTAI 256
Cdd:pfam13415   1 GDKLYIFGGLGFdgQTRLNDLYVYDLDTNTW----TQIGDLPPPRSGHSATYI 49
F_box_assoc_1 TIGR01640
F-box protein interaction domain; This model describes a large family of plant domains, with ...
 32-136 1.82e-03

F-box protein interaction domain; This model describes a large family of plant domains, with several hundred members in Arabidopsis thaliana. Most examples are found C-terminal to an F-box (pfam00646), a 60 amino acid motif involved in ubiquitination of target proteins to mark them for degradation. Two-hybid experiments support the idea that most members are interchangeable F-box subunits of SCF E3 complexes. Some members have two copies of this domain.


Pssm-ID: 273726 [Multi-domain]  Cd Length: 230  Bit Score: 38.88  E-value: 1.82e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820141   32 VSIEDNEVYLPNDEIWTYDVDSGLWKMhlMEGELPPSMSGSCGACINGRLYvFGGYDDKGysNRLYFV---DLRTrdgty 108
Cdd:TIGR01640  58 LCFSDRSGNRNQSEHQVYTLGSNSWRT--IECSPPHHPLKSRGVCINGVLY-YLAYTLKT--NPDYFIvsfDVSS----- 127

                          90       100       110
                  ....*....|....*....|....*....|..
gi 157820141  109 iwEKITKFeGQPPTPR----DKLSCWVYKDRL 136
Cdd:TIGR01640 128 --ERFKEF-IPLPCGNsdsvDYLSLINYKGKL 156
PLN02772 PLN02772
guanylate kinase
 172-245 3.40e-03

guanylate kinase


Pssm-ID: 215414 [Multi-domain]  Cd Length: 398  Bit Score: 38.67  E-value: 3.40e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157820141 172 DVHVFDTKTRTWSQPEIKgGVPPQPRAAHSCAVLgNKGYVFGGRVLQTRMNDLHYLNLDTW--------------VWSGR 237
Cdd:PLN02772  52 GVQILDKITNNWVSPIVL-GTGPKPCKGYSAVVL-NKDRILVIKKGSAPDDSIWFLEVDTPfvreqkkllgtevvAWSKG 129


                 ....*...
gi 157820141 238 ISVNGESP 245
Cdd:PLN02772 130 VRGNAEKP 137
Kelch_4 pfam13418
Galactose oxidase, central domain;
67-122 5.88e-03

Galactose oxidase, central domain;


Pssm-ID: 433191 [Multi-domain]  Cd Length: 49  Bit Score: 34.12  E-value: 5.88e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 157820141   67 PSMSGSCGACINGRLYVFGGYDDKG-YSNRLYFVDLRTRdgtyIWEKItkfeGQPPT 122
Cdd:pfam13418   1 PRAYHTSTSIPDDTIYLFGGEGEDGtLLSDLWVFDLSTN----EWTRL----GSLPS 49
Kelch_6 pfam13964
Kelch motif;
196-235 6.60e-03

Kelch motif;


Pssm-ID: 404790 [Multi-domain]  Cd Length: 50  Bit Score: 34.23  E-value: 6.60e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 157820141  196 PRAAHSCAVLGNKGYVFGGRVLQ-TRMNDLHYLNLDTWVWS 235
Cdd:pfam13964   1 PRTFHSVVSVGGYIYVFGGYTNAsPALNKLEVYNPLTKSWE 41
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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