polycystine-related-Y [Drosophila melanogaster]
List of domain hits
Name | Accession | Description | Interval | E-value | |||||
PLAT super family | cl00011 | PLAT (Polycystin-1, Lipoxygenase, Alpha-Toxin) domain or LH2 (Lipoxygenase homology 2) domain. ... |
1019-1111 | 5.39e-09 | |||||
PLAT (Polycystin-1, Lipoxygenase, Alpha-Toxin) domain or LH2 (Lipoxygenase homology 2) domain. It consists of an eight stranded beta-barrel. The domain can be found in various domain architectures, in case of lipoxygenases, alpha toxin, lipases and polycystin, but also as a single domain or as repeats.The putative function of this domain is to facilitate access to sequestered membrane or micelle bound substrates. The actual alignment was detected with superfamily member cd01752: Pssm-ID: 412108 Cd Length: 120 Bit Score: 55.36 E-value: 5.39e-09
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REJ super family | cl28747 | REJ domain; The REJ (Receptor for Egg Jelly) domain is found in PKD1 and the sperm receptor ... |
217-476 | 3.04e-07 | |||||
REJ domain; The REJ (Receptor for Egg Jelly) domain is found in PKD1 and the sperm receptor for egg jelly. The function of this domain is unknown. The domain is 600 amino acids long so is probably composed of multiple structural domains. There are six completely conserved cysteine residues that may form disulphide bridges. This region contains tandem PKD-like domains. The actual alignment was detected with superfamily member pfam02010: Pssm-ID: 366875 [Multi-domain] Cd Length: 448 Bit Score: 54.43 E-value: 3.04e-07
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Name | Accession | Description | Interval | E-value | |||||
PLAT_polycystin | cd01752 | PLAT/LH2 domain of polycystin-1 like proteins. Polycystins are a large family of membrane ... |
1019-1111 | 5.39e-09 | |||||
PLAT/LH2 domain of polycystin-1 like proteins. Polycystins are a large family of membrane proteins composed of multiple domains, present in fish, invertebrates, mammals, and humans that are widely expressed in various cell types and whose biological functions remain poorly defined. In human, mutations in polycystin-1 (PKD1) and polycystin-2 (PKD2) have been shown to be the cause for autosomal dominant polycystic kidney disease (ADPKD). The generally proposed function of PLAT/LH2 domains is to mediate interaction with lipids or membrane bound proteins. Pssm-ID: 238850 Cd Length: 120 Bit Score: 55.36 E-value: 5.39e-09
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REJ | pfam02010 | REJ domain; The REJ (Receptor for Egg Jelly) domain is found in PKD1 and the sperm receptor ... |
217-476 | 3.04e-07 | |||||
REJ domain; The REJ (Receptor for Egg Jelly) domain is found in PKD1 and the sperm receptor for egg jelly. The function of this domain is unknown. The domain is 600 amino acids long so is probably composed of multiple structural domains. There are six completely conserved cysteine residues that may form disulphide bridges. This region contains tandem PKD-like domains. Pssm-ID: 366875 [Multi-domain] Cd Length: 448 Bit Score: 54.43 E-value: 3.04e-07
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PLAT | pfam01477 | PLAT/LH2 domain; This domain is found in a variety of membrane or lipid associated proteins. ... |
1017-1124 | 1.26e-06 | |||||
PLAT/LH2 domain; This domain is found in a variety of membrane or lipid associated proteins. It is called the PLAT (Polycystin-1, Lipoxygenase, Alpha-Toxin) domain or LH2 (Lipoxygenase homology) domain. The known structure of pancreatic lipase shows this domain binds to procolipase pfam01114, which mediates membrane association. So it appears possible that this domain mediates membrane attachment via other protein binding partners. The structure of this domain is known for many members of the family and is composed of a beta sandwich. Pssm-ID: 396180 Cd Length: 115 Bit Score: 48.58 E-value: 1.26e-06
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Name | Accession | Description | Interval | E-value | |||||
PLAT_polycystin | cd01752 | PLAT/LH2 domain of polycystin-1 like proteins. Polycystins are a large family of membrane ... |
1019-1111 | 5.39e-09 | |||||
PLAT/LH2 domain of polycystin-1 like proteins. Polycystins are a large family of membrane proteins composed of multiple domains, present in fish, invertebrates, mammals, and humans that are widely expressed in various cell types and whose biological functions remain poorly defined. In human, mutations in polycystin-1 (PKD1) and polycystin-2 (PKD2) have been shown to be the cause for autosomal dominant polycystic kidney disease (ADPKD). The generally proposed function of PLAT/LH2 domains is to mediate interaction with lipids or membrane bound proteins. Pssm-ID: 238850 Cd Length: 120 Bit Score: 55.36 E-value: 5.39e-09
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REJ | pfam02010 | REJ domain; The REJ (Receptor for Egg Jelly) domain is found in PKD1 and the sperm receptor ... |
217-476 | 3.04e-07 | |||||
REJ domain; The REJ (Receptor for Egg Jelly) domain is found in PKD1 and the sperm receptor for egg jelly. The function of this domain is unknown. The domain is 600 amino acids long so is probably composed of multiple structural domains. There are six completely conserved cysteine residues that may form disulphide bridges. This region contains tandem PKD-like domains. Pssm-ID: 366875 [Multi-domain] Cd Length: 448 Bit Score: 54.43 E-value: 3.04e-07
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PLAT | cd00113 | PLAT (Polycystin-1, Lipoxygenase, Alpha-Toxin) domain or LH2 (Lipoxygenase homology 2) domain. ... |
1017-1124 | 7.76e-07 | |||||
PLAT (Polycystin-1, Lipoxygenase, Alpha-Toxin) domain or LH2 (Lipoxygenase homology 2) domain. It consists of an eight stranded beta-barrel. The domain can be found in various domain architectures, in case of lipoxygenases, alpha toxin, lipases and polycystin, but also as a single domain or as repeats.The putative function of this domain is to facilitate access to sequestered membrane or micelle bound substrates. Pssm-ID: 238061 Cd Length: 116 Bit Score: 48.87 E-value: 7.76e-07
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PLAT | pfam01477 | PLAT/LH2 domain; This domain is found in a variety of membrane or lipid associated proteins. ... |
1017-1124 | 1.26e-06 | |||||
PLAT/LH2 domain; This domain is found in a variety of membrane or lipid associated proteins. It is called the PLAT (Polycystin-1, Lipoxygenase, Alpha-Toxin) domain or LH2 (Lipoxygenase homology) domain. The known structure of pancreatic lipase shows this domain binds to procolipase pfam01114, which mediates membrane association. So it appears possible that this domain mediates membrane attachment via other protein binding partners. The structure of this domain is known for many members of the family and is composed of a beta sandwich. Pssm-ID: 396180 Cd Length: 115 Bit Score: 48.58 E-value: 1.26e-06
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Blast search parameters | ||||
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