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Conserved domains on  [gi|164450481|ref|NP_001106748|]
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kininogen-1 isoform II precursor [Bos taurus]

Protein Classification

CY domain-containing protein( domain architecture ID 11249404)

CY domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Cystatin pfam00031
Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. ...
 263-357 6.04e-30

Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. Typically, either the N-terminal or C-terminal end is very divergent. But splitting into two domains would make very short families. pfam00666 is related to this family but has not been included.


:

Pssm-ID: 425431  Cd Length: 92  Bit Score: 113.20  E-value: 6.04e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164450481  263 GCPKPIPVDSPDLEEALNHSIAKLNAEHDGtFYFKIDTVKKATVQVVGGLKYSIVFIARETTCSKgsNEELTKSCEINIH 342
Cdd:pfam00031   1 GGLSPIPDNSPELQEALDFALAEYNAKTDN-YYFELVEVKRAKSQVVAGTNYFIKVEVGETDCSK--SKKLLEDCPLLDE 77

                          90
                  ....*....|....*
gi 164450481  343 GQILHCDANVYVVPW 357
Cdd:pfam00031  78 KWLGLCSAQVYKVPW 92
Cystatin pfam00031
Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. ...
 143-236 3.33e-28

Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. Typically, either the N-terminal or C-terminal end is very divergent. But splitting into two domains would make very short families. pfam00666 is related to this family but has not been included.


:

Pssm-ID: 425431  Cd Length: 92  Bit Score: 108.19  E-value: 3.33e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164450481  143 GCVHPISTKSPDLEPVLRYAIQYFNNNTsHSHLFDLKEVKRAQKQVVSGWNYEVNYSIAQTNCSKeeFSFLTPDCKSLSS 222
Cdd:pfam00031   1 GGLSPIPDNSPELQEALDFALAEYNAKT-DNYYFELVEVKRAKSQVVAGTNYFIKVEVGETDCSK--SKKLLEDCPLLDE 77

                          90
                  ....*....|....
gi 164450481  223 GDTGECTDKAHVDV 236
Cdd:pfam00031  78 KWLGLCSAQVYKVP 91
CY smart00043
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 23-126 2.68e-18

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


:

Pssm-ID: 214484  Cd Length: 107  Bit Score: 80.55  E-value: 2.68e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164450481    23 QEIDCNDQDVFKAVDAALTKYNSENKSGNQFVLYRITEVARMDNPDTFYSLKYQIKEGDCPFQSNKtWQDCDYKDSAQaa 102
Cdd:smart00043   7 SDVPPNDPEVQEAADFAVAEYNKKSNDKYELRVIKVVSAKSQVVAGTNYYLKVEVGETNCKKLSVD-LENCPFLDQGE-- 83

                           90       100
                   ....*....|....*....|....*
gi 164450481   103 tGQCTATV-AKRGNMKFSVAIQTCL 126
Cdd:smart00043  84 -KFCTAKVwEKPWENKIKLVEFKCT 107
 
Name Accession Description Interval E-value
Cystatin pfam00031
Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. ...
 263-357 6.04e-30

Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. Typically, either the N-terminal or C-terminal end is very divergent. But splitting into two domains would make very short families. pfam00666 is related to this family but has not been included.


Pssm-ID: 425431  Cd Length: 92  Bit Score: 113.20  E-value: 6.04e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164450481  263 GCPKPIPVDSPDLEEALNHSIAKLNAEHDGtFYFKIDTVKKATVQVVGGLKYSIVFIARETTCSKgsNEELTKSCEINIH 342
Cdd:pfam00031   1 GGLSPIPDNSPELQEALDFALAEYNAKTDN-YYFELVEVKRAKSQVVAGTNYFIKVEVGETDCSK--SKKLLEDCPLLDE 77

                          90
                  ....*....|....*
gi 164450481  343 GQILHCDANVYVVPW 357
Cdd:pfam00031  78 KWLGLCSAQVYKVPW 92
CY smart00043
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 261-368 4.46e-29

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 214484  Cd Length: 107  Bit Score: 111.37  E-value: 4.46e-29
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164450481   261 CVGCPKPIPVDSPDLEEALNHSIAKLNAEHDGTFYFKIDTVKKATVQVVGGLKYSIVFIARETTCSKGSneELTKSCEIN 340
Cdd:smart00043   2 CLGGPSDVPPNDPEVQEAADFAVAEYNKKSNDKYELRVIKVVSAKSQVVAGTNYYLKVEVGETNCKKLS--VDLENCPFL 79

                           90       100
                   ....*....|....*....|....*....
gi 164450481   341 IHGQIlHCDANVYVVPWEEK-VYPTVNCQ 368
Cdd:smart00043  80 DQGEK-FCTAKVWEKPWENKiKLVEFKCT 107
Cystatin pfam00031
Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. ...
 143-236 3.33e-28

Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. Typically, either the N-terminal or C-terminal end is very divergent. But splitting into two domains would make very short families. pfam00666 is related to this family but has not been included.


Pssm-ID: 425431  Cd Length: 92  Bit Score: 108.19  E-value: 3.33e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164450481  143 GCVHPISTKSPDLEPVLRYAIQYFNNNTsHSHLFDLKEVKRAQKQVVSGWNYEVNYSIAQTNCSKeeFSFLTPDCKSLSS 222
Cdd:pfam00031   1 GGLSPIPDNSPELQEALDFALAEYNAKT-DNYYFELVEVKRAKSQVVAGTNYFIKVEVGETDCSK--SKKLLEDCPLLDE 77

                          90
                  ....*....|....
gi 164450481  223 GDTGECTDKAHVDV 236
Cdd:pfam00031  78 KWLGLCSAQVYKVP 91
CY cd00042
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 263-367 4.65e-27

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 238002 [Multi-domain]  Cd Length: 105  Bit Score: 105.25  E-value: 4.65e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164450481 263 GCPKPIPVDSPDLEEALNHSIAKLNAEHDGTfYFKIDTVKKATVQVVGGLKYSIVFIARETTCSKGSNEELTKSCEINIH 342
Cdd:cd00042    1 GGPSDIPANDPEVQELADFAVAEYNKKSNDK-YLEFFKVLSAKSQVVAGTNYYITVEAGDTNCKKSSVPLDCPDCKLLEE 79

                         90       100
                 ....*....|....*....|....*.
gi 164450481 343 GQILHCDANVYVVPWEE-KVYPTVNC 367
Cdd:cd00042   80 GKKKFCTAKVWEKPWENfKELLSFKC 105
CY cd00042
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 143-247 4.32e-26

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 238002 [Multi-domain]  Cd Length: 105  Bit Score: 102.55  E-value: 4.32e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164450481 143 GCVHPISTKSPDLEPVLRYAIQYFNNNTSHSHlFDLKEVKRAQKQVVSGWNYEVNYSIAQTNCSKEEFSFLTPDCKSLSS 222
Cdd:cd00042    1 GGPSDIPANDPEVQELADFAVAEYNKKSNDKY-LEFFKVLSAKSQVVAGTNYYITVEAGDTNCKKSSVPLDCPDCKLLEE 79

                         90       100
                 ....*....|....*....|....*.
gi 164450481 223 GDTGECTDKAHVDVKLR-ISSFSQKC 247
Cdd:cd00042   80 GKKKFCTAKVWEKPWENfKELLSFKC 105
CY smart00043
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 141-248 8.01e-26

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 214484  Cd Length: 107  Bit Score: 102.12  E-value: 8.01e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164450481   141 CLGCVHPISTKSPDLEPVLRYAIQYFNNNTSHSHLFDLKEVKRAQKQVVSGWNYEVNYSIAQTNCSKEefSFLTPDCKSL 220
Cdd:smart00043   2 CLGGPSDVPPNDPEVQEAADFAVAEYNKKSNDKYELRVIKVVSAKSQVVAGTNYYLKVEVGETNCKKL--SVDLENCPFL 79

                           90       100
                   ....*....|....*....|....*....
gi 164450481   221 SSGDtGECTDKA-HVDVKLRISSFSQKCD 248
Cdd:smart00043  80 DQGE-KFCTAKVwEKPWENKIKLVEFKCT 107
CY smart00043
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 23-126 2.68e-18

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 214484  Cd Length: 107  Bit Score: 80.55  E-value: 2.68e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164450481    23 QEIDCNDQDVFKAVDAALTKYNSENKSGNQFVLYRITEVARMDNPDTFYSLKYQIKEGDCPFQSNKtWQDCDYKDSAQaa 102
Cdd:smart00043   7 SDVPPNDPEVQEAADFAVAEYNKKSNDKYELRVIKVVSAKSQVVAGTNYYLKVEVGETNCKKLSVD-LENCPFLDQGE-- 83

                           90       100
                   ....*....|....*....|....*
gi 164450481   103 tGQCTATV-AKRGNMKFSVAIQTCL 126
Cdd:smart00043  84 -KFCTAKVwEKPWENKIKLVEFKCT 107
Cystatin pfam00031
Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. ...
 24-115 3.45e-18

Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. Typically, either the N-terminal or C-terminal end is very divergent. But splitting into two domains would make very short families. pfam00666 is related to this family but has not been included.


Pssm-ID: 425431  Cd Length: 92  Bit Score: 79.69  E-value: 3.45e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164450481   24 EIDCNDQDVFKAVDAALTKYNSENkSGNQFVLYRITEVARMDNPDTFYSLKYQIKEGDCPFqSNKTWQDCDYKDsaQAAT 103
Cdd:pfam00031   5 PIPDNSPELQEALDFALAEYNAKT-DNYYFELVEVKRAKSQVVAGTNYFIKVEVGETDCSK-SKKLLEDCPLLD--EKWL 80

                          90
                  ....*....|..
gi 164450481  104 GQCTATVAKRGN 115
Cdd:pfam00031  81 GLCSAQVYKVPW 92
CY cd00042
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 23-118 6.94e-05

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 238002 [Multi-domain]  Cd Length: 105  Bit Score: 42.46  E-value: 6.94e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164450481  23 QEIDCNDQDVFKAVDAALTKYNSENKSGNqfvlYRITEV--ARMDN-PDTFYSLKYQIKEGDCPFQSNKTW-QDCDYKDS 98
Cdd:cd00042    4 SDIPANDPEVQELADFAVAEYNKKSNDKY----LEFFKVlsAKSQVvAGTNYYITVEAGDTNCKKSSVPLDcPDCKLLEE 79

                         90       100
                 ....*....|....*....|
gi 164450481  99 AQaaTGQCTATVAKRGNMKF 118
Cdd:cd00042   80 GK--KKFCTAKVWEKPWENF 97
 
Name Accession Description Interval E-value
Cystatin pfam00031
Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. ...
 263-357 6.04e-30

Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. Typically, either the N-terminal or C-terminal end is very divergent. But splitting into two domains would make very short families. pfam00666 is related to this family but has not been included.


Pssm-ID: 425431  Cd Length: 92  Bit Score: 113.20  E-value: 6.04e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164450481  263 GCPKPIPVDSPDLEEALNHSIAKLNAEHDGtFYFKIDTVKKATVQVVGGLKYSIVFIARETTCSKgsNEELTKSCEINIH 342
Cdd:pfam00031   1 GGLSPIPDNSPELQEALDFALAEYNAKTDN-YYFELVEVKRAKSQVVAGTNYFIKVEVGETDCSK--SKKLLEDCPLLDE 77

                          90
                  ....*....|....*
gi 164450481  343 GQILHCDANVYVVPW 357
Cdd:pfam00031  78 KWLGLCSAQVYKVPW 92
CY smart00043
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 261-368 4.46e-29

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 214484  Cd Length: 107  Bit Score: 111.37  E-value: 4.46e-29
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164450481   261 CVGCPKPIPVDSPDLEEALNHSIAKLNAEHDGTFYFKIDTVKKATVQVVGGLKYSIVFIARETTCSKGSneELTKSCEIN 340
Cdd:smart00043   2 CLGGPSDVPPNDPEVQEAADFAVAEYNKKSNDKYELRVIKVVSAKSQVVAGTNYYLKVEVGETNCKKLS--VDLENCPFL 79

                           90       100
                   ....*....|....*....|....*....
gi 164450481   341 IHGQIlHCDANVYVVPWEEK-VYPTVNCQ 368
Cdd:smart00043  80 DQGEK-FCTAKVWEKPWENKiKLVEFKCT 107
Cystatin pfam00031
Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. ...
 143-236 3.33e-28

Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. Typically, either the N-terminal or C-terminal end is very divergent. But splitting into two domains would make very short families. pfam00666 is related to this family but has not been included.


Pssm-ID: 425431  Cd Length: 92  Bit Score: 108.19  E-value: 3.33e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164450481  143 GCVHPISTKSPDLEPVLRYAIQYFNNNTsHSHLFDLKEVKRAQKQVVSGWNYEVNYSIAQTNCSKeeFSFLTPDCKSLSS 222
Cdd:pfam00031   1 GGLSPIPDNSPELQEALDFALAEYNAKT-DNYYFELVEVKRAKSQVVAGTNYFIKVEVGETDCSK--SKKLLEDCPLLDE 77

                          90
                  ....*....|....
gi 164450481  223 GDTGECTDKAHVDV 236
Cdd:pfam00031  78 KWLGLCSAQVYKVP 91
CY cd00042
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 263-367 4.65e-27

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 238002 [Multi-domain]  Cd Length: 105  Bit Score: 105.25  E-value: 4.65e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164450481 263 GCPKPIPVDSPDLEEALNHSIAKLNAEHDGTfYFKIDTVKKATVQVVGGLKYSIVFIARETTCSKGSNEELTKSCEINIH 342
Cdd:cd00042    1 GGPSDIPANDPEVQELADFAVAEYNKKSNDK-YLEFFKVLSAKSQVVAGTNYYITVEAGDTNCKKSSVPLDCPDCKLLEE 79

                         90       100
                 ....*....|....*....|....*.
gi 164450481 343 GQILHCDANVYVVPWEE-KVYPTVNC 367
Cdd:cd00042   80 GKKKFCTAKVWEKPWENfKELLSFKC 105
CY cd00042
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 143-247 4.32e-26

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 238002 [Multi-domain]  Cd Length: 105  Bit Score: 102.55  E-value: 4.32e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164450481 143 GCVHPISTKSPDLEPVLRYAIQYFNNNTSHSHlFDLKEVKRAQKQVVSGWNYEVNYSIAQTNCSKEEFSFLTPDCKSLSS 222
Cdd:cd00042    1 GGPSDIPANDPEVQELADFAVAEYNKKSNDKY-LEFFKVLSAKSQVVAGTNYYITVEAGDTNCKKSSVPLDCPDCKLLEE 79

                         90       100
                 ....*....|....*....|....*.
gi 164450481 223 GDTGECTDKAHVDVKLR-ISSFSQKC 247
Cdd:cd00042   80 GKKKFCTAKVWEKPWENfKELLSFKC 105
CY smart00043
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 141-248 8.01e-26

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 214484  Cd Length: 107  Bit Score: 102.12  E-value: 8.01e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164450481   141 CLGCVHPISTKSPDLEPVLRYAIQYFNNNTSHSHLFDLKEVKRAQKQVVSGWNYEVNYSIAQTNCSKEefSFLTPDCKSL 220
Cdd:smart00043   2 CLGGPSDVPPNDPEVQEAADFAVAEYNKKSNDKYELRVIKVVSAKSQVVAGTNYYLKVEVGETNCKKL--SVDLENCPFL 79

                           90       100
                   ....*....|....*....|....*....
gi 164450481   221 SSGDtGECTDKA-HVDVKLRISSFSQKCD 248
Cdd:smart00043  80 DQGE-KFCTAKVwEKPWENKIKLVEFKCT 107
CY smart00043
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 23-126 2.68e-18

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 214484  Cd Length: 107  Bit Score: 80.55  E-value: 2.68e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164450481    23 QEIDCNDQDVFKAVDAALTKYNSENKSGNQFVLYRITEVARMDNPDTFYSLKYQIKEGDCPFQSNKtWQDCDYKDSAQaa 102
Cdd:smart00043   7 SDVPPNDPEVQEAADFAVAEYNKKSNDKYELRVIKVVSAKSQVVAGTNYYLKVEVGETNCKKLSVD-LENCPFLDQGE-- 83

                           90       100
                   ....*....|....*....|....*
gi 164450481   103 tGQCTATV-AKRGNMKFSVAIQTCL 126
Cdd:smart00043  84 -KFCTAKVwEKPWENKIKLVEFKCT 107
Cystatin pfam00031
Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. ...
 24-115 3.45e-18

Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. Typically, either the N-terminal or C-terminal end is very divergent. But splitting into two domains would make very short families. pfam00666 is related to this family but has not been included.


Pssm-ID: 425431  Cd Length: 92  Bit Score: 79.69  E-value: 3.45e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164450481   24 EIDCNDQDVFKAVDAALTKYNSENkSGNQFVLYRITEVARMDNPDTFYSLKYQIKEGDCPFqSNKTWQDCDYKDsaQAAT 103
Cdd:pfam00031   5 PIPDNSPELQEALDFALAEYNAKT-DNYYFELVEVKRAKSQVVAGTNYFIKVEVGETDCSK-SKKLLEDCPLLD--EKWL 80

                          90
                  ....*....|..
gi 164450481  104 GQCTATVAKRGN 115
Cdd:pfam00031  81 GLCSAQVYKVPW 92
Cathelicidins pfam00666
Cathelicidin; A novel protein family, showing a conserved proregion and a variable ...
 35-113 1.01e-05

Cathelicidin; A novel protein family, showing a conserved proregion and a variable carboxyl-terminal antimicrobial domain. This region shows similarity to cystatins.


Pssm-ID: 395539  Cd Length: 101  Bit Score: 44.41  E-value: 1.01e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164450481   35 AVDAALTKYNSENKSGNQFVLYRITEVARMD-NPDTFYSLKYQIKEGDCPFQSNKTWQDCDYKDsaQAATGQCTATVAKR 113
Cdd:pfam00666   8 AVLRAVDQFNEQSSEANLYRLLELDPPPQDDeDPDTPKPVSFRVKETVCPRTTQQPPEQCDFKE--NGLVKRCVGTVTLN 85
CY cd00042
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 23-118 6.94e-05

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 238002 [Multi-domain]  Cd Length: 105  Bit Score: 42.46  E-value: 6.94e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164450481  23 QEIDCNDQDVFKAVDAALTKYNSENKSGNqfvlYRITEV--ARMDN-PDTFYSLKYQIKEGDCPFQSNKTW-QDCDYKDS 98
Cdd:cd00042    4 SDIPANDPEVQELADFAVAEYNKKSNDKY----LEFFKVlsAKSQVvAGTNYYITVEAGDTNCKKSSVPLDcPDCKLLEE 79

                         90       100
                 ....*....|....*....|
gi 164450481  99 AQaaTGQCTATVAKRGNMKF 118
Cdd:cd00042   80 GK--KKFCTAKVWEKPWENF 97
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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