72 kDa type IV collagenase isoform 2 [Homo sapiens]
Protein Classification
ZnMc_MMP and HX domain-containing protein( domain architecture ID 12021233)
protein containing domains PG_binding_1, ZnMc_MMP, FN2, and HX
List of domain hits
| Name | Accession | Description | Interval | E-value | ||||||
| HX | cd00094 | Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. ... |
416-610 | 3.32e-76 | ||||||
Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of metalloproteinases (TIMPs). This CD contains 4 instances of the repeat. : Pssm-ID: 238046 [Multi-domain] Cd Length: 194 Bit Score: 240.68 E-value: 3.32e-76
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| Peptidase_M10 | pfam00413 | Matrixin; The members of this family are enzymes that cleave peptides. These proteases require ... |
68-396 | 1.07e-68 | ||||||
Matrixin; The members of this family are enzymes that cleave peptides. These proteases require zinc for catalysis. : Pssm-ID: 425668 [Multi-domain] Cd Length: 159 Bit Score: 219.80 E-value: 1.07e-68
|
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| FN2 | smart00059 | Fibronectin type 2 domain; One of three types of internal repeat within the plasma protein, ... |
292-340 | 4.90e-24 | ||||||
Fibronectin type 2 domain; One of three types of internal repeat within the plasma protein, fibronectin. Also occurs in coagulation factor XII, 2 type IV collagenases, PDC-109, and cation-independent mannose-6-phosphate and secretory phospholipase A2 receptors. In fibronectin, PDC-109, and the collagenases, this domain contributes to collagen-binding function. : Pssm-ID: 128373 Cd Length: 49 Bit Score: 95.06 E-value: 4.90e-24
|
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| FN2 | smart00059 | Fibronectin type 2 domain; One of three types of internal repeat within the plasma protein, ... |
234-282 | 4.36e-23 | ||||||
Fibronectin type 2 domain; One of three types of internal repeat within the plasma protein, fibronectin. Also occurs in coagulation factor XII, 2 type IV collagenases, PDC-109, and cation-independent mannose-6-phosphate and secretory phospholipase A2 receptors. In fibronectin, PDC-109, and the collagenases, this domain contributes to collagen-binding function. : Pssm-ID: 128373 Cd Length: 49 Bit Score: 92.36 E-value: 4.36e-23
|
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| FN2 | smart00059 | Fibronectin type 2 domain; One of three types of internal repeat within the plasma protein, ... |
176-224 | 2.04e-22 | ||||||
Fibronectin type 2 domain; One of three types of internal repeat within the plasma protein, fibronectin. Also occurs in coagulation factor XII, 2 type IV collagenases, PDC-109, and cation-independent mannose-6-phosphate and secretory phospholipase A2 receptors. In fibronectin, PDC-109, and the collagenases, this domain contributes to collagen-binding function. : Pssm-ID: 128373 Cd Length: 49 Bit Score: 90.44 E-value: 2.04e-22
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| PG_binding_1 | pfam01471 | Putative peptidoglycan binding domain; This domain is composed of three alpha helices. This ... |
20-47 | 4.83e-04 | ||||||
Putative peptidoglycan binding domain; This domain is composed of three alpha helices. This domain is found at the N or C terminus of a variety of enzymes involved in bacterial cell wall degradation. This domain may have a general peptidoglycan binding function. This family is found N-terminal to the catalytic domain of matrixins. The domain is found to bind peptidoglycan experimentally. : Pssm-ID: 460223 [Multi-domain] Cd Length: 57 Bit Score: 38.27 E-value: 4.83e-04
|
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| Name | Accession | Description | Interval | E-value | ||||||
| HX | cd00094 | Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. ... |
416-610 | 3.32e-76 | ||||||
Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of metalloproteinases (TIMPs). This CD contains 4 instances of the repeat. Pssm-ID: 238046 [Multi-domain] Cd Length: 194 Bit Score: 240.68 E-value: 3.32e-76
|
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| Peptidase_M10 | pfam00413 | Matrixin; The members of this family are enzymes that cleave peptides. These proteases require ... |
68-396 | 1.07e-68 | ||||||
Matrixin; The members of this family are enzymes that cleave peptides. These proteases require zinc for catalysis. Pssm-ID: 425668 [Multi-domain] Cd Length: 159 Bit Score: 219.80 E-value: 1.07e-68
|
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| ZnMc_MMP | cd04278 | Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are ... |
68-396 | 3.99e-61 | ||||||
Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are responsible for a great deal of pericellular proteolysis of extracellular matrix and cell surface molecules, playing crucial roles in morphogenesis, cell fate specification, cell migration, tissue repair, tumorigenesis, gain or loss of tissue-specific functions, and apoptosis. In many instances, they are anchored to cell membranes via trans-membrane domains, and their activity is controlled via TIMPs (tissue inhibitors of metalloproteinases). Pssm-ID: 239805 [Multi-domain] Cd Length: 157 Bit Score: 199.74 E-value: 3.99e-61
|
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| FN2 | smart00059 | Fibronectin type 2 domain; One of three types of internal repeat within the plasma protein, ... |
292-340 | 4.90e-24 | ||||||
Fibronectin type 2 domain; One of three types of internal repeat within the plasma protein, fibronectin. Also occurs in coagulation factor XII, 2 type IV collagenases, PDC-109, and cation-independent mannose-6-phosphate and secretory phospholipase A2 receptors. In fibronectin, PDC-109, and the collagenases, this domain contributes to collagen-binding function. Pssm-ID: 128373 Cd Length: 49 Bit Score: 95.06 E-value: 4.90e-24
|
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| FN2 | smart00059 | Fibronectin type 2 domain; One of three types of internal repeat within the plasma protein, ... |
234-282 | 4.36e-23 | ||||||
Fibronectin type 2 domain; One of three types of internal repeat within the plasma protein, fibronectin. Also occurs in coagulation factor XII, 2 type IV collagenases, PDC-109, and cation-independent mannose-6-phosphate and secretory phospholipase A2 receptors. In fibronectin, PDC-109, and the collagenases, this domain contributes to collagen-binding function. Pssm-ID: 128373 Cd Length: 49 Bit Score: 92.36 E-value: 4.36e-23
|
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| FN2 | smart00059 | Fibronectin type 2 domain; One of three types of internal repeat within the plasma protein, ... |
176-224 | 2.04e-22 | ||||||
Fibronectin type 2 domain; One of three types of internal repeat within the plasma protein, fibronectin. Also occurs in coagulation factor XII, 2 type IV collagenases, PDC-109, and cation-independent mannose-6-phosphate and secretory phospholipase A2 receptors. In fibronectin, PDC-109, and the collagenases, this domain contributes to collagen-binding function. Pssm-ID: 128373 Cd Length: 49 Bit Score: 90.44 E-value: 2.04e-22
|
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| FN2 | cd00062 | Fibronectin Type II domain: FN2 is one of three types of internal repeats which combine to ... |
293-340 | 8.39e-22 | ||||||
Fibronectin Type II domain: FN2 is one of three types of internal repeats which combine to form larger domains within fibronectin. Fibronectin, a plasma protein that binds cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin, usually exists as a dimer in plasma and as an insoluble multimer in extracellular matrices. Dimers of nearly identical subunits are linked by a disulfide bond close to their C-terminus. Fibronectin is composed of 3 types of modules, FN1,FN2 and FN3. The collagen binding domain contains four FN1 and two FN2 repeats. Pssm-ID: 238019 Cd Length: 48 Bit Score: 88.52 E-value: 8.39e-22
|
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| FN2 | cd00062 | Fibronectin Type II domain: FN2 is one of three types of internal repeats which combine to ... |
235-282 | 1.08e-20 | ||||||
Fibronectin Type II domain: FN2 is one of three types of internal repeats which combine to form larger domains within fibronectin. Fibronectin, a plasma protein that binds cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin, usually exists as a dimer in plasma and as an insoluble multimer in extracellular matrices. Dimers of nearly identical subunits are linked by a disulfide bond close to their C-terminus. Fibronectin is composed of 3 types of modules, FN1,FN2 and FN3. The collagen binding domain contains four FN1 and two FN2 repeats. Pssm-ID: 238019 Cd Length: 48 Bit Score: 85.43 E-value: 1.08e-20
|
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| ZnMc | smart00235 | Zinc-dependent metalloprotease; Neutral zinc metallopeptidases. This alignment represents a ... |
65-168 | 4.97e-20 | ||||||
Zinc-dependent metalloprotease; Neutral zinc metallopeptidases. This alignment represents a subset of known subfamilies. Highest similarity occurs in the HExxH zinc-binding site/ active site. Pssm-ID: 214576 [Multi-domain] Cd Length: 139 Bit Score: 86.64 E-value: 4.97e-20
|
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| FN2 | cd00062 | Fibronectin Type II domain: FN2 is one of three types of internal repeats which combine to ... |
177-224 | 8.51e-20 | ||||||
Fibronectin Type II domain: FN2 is one of three types of internal repeats which combine to form larger domains within fibronectin. Fibronectin, a plasma protein that binds cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin, usually exists as a dimer in plasma and as an insoluble multimer in extracellular matrices. Dimers of nearly identical subunits are linked by a disulfide bond close to their C-terminus. Fibronectin is composed of 3 types of modules, FN1,FN2 and FN3. The collagen binding domain contains four FN1 and two FN2 repeats. Pssm-ID: 238019 Cd Length: 48 Bit Score: 82.74 E-value: 8.51e-20
|
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| fn2 | pfam00040 | Fibronectin type II domain; |
299-340 | 1.05e-18 | ||||||
Fibronectin type II domain; Pssm-ID: 459645 Cd Length: 42 Bit Score: 79.54 E-value: 1.05e-18
|
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| fn2 | pfam00040 | Fibronectin type II domain; |
183-224 | 1.33e-18 | ||||||
Fibronectin type II domain; Pssm-ID: 459645 Cd Length: 42 Bit Score: 79.15 E-value: 1.33e-18
|
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| fn2 | pfam00040 | Fibronectin type II domain; |
241-282 | 3.29e-18 | ||||||
Fibronectin type II domain; Pssm-ID: 459645 Cd Length: 42 Bit Score: 78.00 E-value: 3.29e-18
|
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| HX | smart00120 | Hemopexin-like repeats; Hemopexin is a heme-binding protein that transports heme to the liver. ... |
518-564 | 4.60e-10 | ||||||
Hemopexin-like repeats; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of metalloproteinases (TIMPs). Pssm-ID: 214524 [Multi-domain] Cd Length: 45 Bit Score: 54.94 E-value: 4.60e-10
|
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| Hemopexin | pfam00045 | Hemopexin; Hemopexin is a heme-binding protein that transports heme to the liver. ... |
518-564 | 3.48e-08 | ||||||
Hemopexin; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metallopeptidases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of metallopeptidases (TIMPs). Pssm-ID: 395000 [Multi-domain] Cd Length: 44 Bit Score: 49.87 E-value: 3.48e-08
|
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| PG_binding_1 | pfam01471 | Putative peptidoglycan binding domain; This domain is composed of three alpha helices. This ... |
20-47 | 4.83e-04 | ||||||
Putative peptidoglycan binding domain; This domain is composed of three alpha helices. This domain is found at the N or C terminus of a variety of enzymes involved in bacterial cell wall degradation. This domain may have a general peptidoglycan binding function. This family is found N-terminal to the catalytic domain of matrixins. The domain is found to bind peptidoglycan experimentally. Pssm-ID: 460223 [Multi-domain] Cd Length: 57 Bit Score: 38.27 E-value: 4.83e-04
|
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| Name | Accession | Description | Interval | E-value | ||||||
| HX | cd00094 | Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. ... |
416-610 | 3.32e-76 | ||||||
Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of metalloproteinases (TIMPs). This CD contains 4 instances of the repeat. Pssm-ID: 238046 [Multi-domain] Cd Length: 194 Bit Score: 240.68 E-value: 3.32e-76
|
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| Peptidase_M10 | pfam00413 | Matrixin; The members of this family are enzymes that cleave peptides. These proteases require ... |
68-396 | 1.07e-68 | ||||||
Matrixin; The members of this family are enzymes that cleave peptides. These proteases require zinc for catalysis. Pssm-ID: 425668 [Multi-domain] Cd Length: 159 Bit Score: 219.80 E-value: 1.07e-68
|
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| ZnMc_MMP | cd04278 | Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are ... |
68-396 | 3.99e-61 | ||||||
Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are responsible for a great deal of pericellular proteolysis of extracellular matrix and cell surface molecules, playing crucial roles in morphogenesis, cell fate specification, cell migration, tissue repair, tumorigenesis, gain or loss of tissue-specific functions, and apoptosis. In many instances, they are anchored to cell membranes via trans-membrane domains, and their activity is controlled via TIMPs (tissue inhibitors of metalloproteinases). Pssm-ID: 239805 [Multi-domain] Cd Length: 157 Bit Score: 199.74 E-value: 3.99e-61
|
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| FN2 | smart00059 | Fibronectin type 2 domain; One of three types of internal repeat within the plasma protein, ... |
292-340 | 4.90e-24 | ||||||
Fibronectin type 2 domain; One of three types of internal repeat within the plasma protein, fibronectin. Also occurs in coagulation factor XII, 2 type IV collagenases, PDC-109, and cation-independent mannose-6-phosphate and secretory phospholipase A2 receptors. In fibronectin, PDC-109, and the collagenases, this domain contributes to collagen-binding function. Pssm-ID: 128373 Cd Length: 49 Bit Score: 95.06 E-value: 4.90e-24
|
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| FN2 | smart00059 | Fibronectin type 2 domain; One of three types of internal repeat within the plasma protein, ... |
234-282 | 4.36e-23 | ||||||
Fibronectin type 2 domain; One of three types of internal repeat within the plasma protein, fibronectin. Also occurs in coagulation factor XII, 2 type IV collagenases, PDC-109, and cation-independent mannose-6-phosphate and secretory phospholipase A2 receptors. In fibronectin, PDC-109, and the collagenases, this domain contributes to collagen-binding function. Pssm-ID: 128373 Cd Length: 49 Bit Score: 92.36 E-value: 4.36e-23
|
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| FN2 | smart00059 | Fibronectin type 2 domain; One of three types of internal repeat within the plasma protein, ... |
176-224 | 2.04e-22 | ||||||
Fibronectin type 2 domain; One of three types of internal repeat within the plasma protein, fibronectin. Also occurs in coagulation factor XII, 2 type IV collagenases, PDC-109, and cation-independent mannose-6-phosphate and secretory phospholipase A2 receptors. In fibronectin, PDC-109, and the collagenases, this domain contributes to collagen-binding function. Pssm-ID: 128373 Cd Length: 49 Bit Score: 90.44 E-value: 2.04e-22
|
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| FN2 | cd00062 | Fibronectin Type II domain: FN2 is one of three types of internal repeats which combine to ... |
293-340 | 8.39e-22 | ||||||
Fibronectin Type II domain: FN2 is one of three types of internal repeats which combine to form larger domains within fibronectin. Fibronectin, a plasma protein that binds cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin, usually exists as a dimer in plasma and as an insoluble multimer in extracellular matrices. Dimers of nearly identical subunits are linked by a disulfide bond close to their C-terminus. Fibronectin is composed of 3 types of modules, FN1,FN2 and FN3. The collagen binding domain contains four FN1 and two FN2 repeats. Pssm-ID: 238019 Cd Length: 48 Bit Score: 88.52 E-value: 8.39e-22
|
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| FN2 | cd00062 | Fibronectin Type II domain: FN2 is one of three types of internal repeats which combine to ... |
235-282 | 1.08e-20 | ||||||
Fibronectin Type II domain: FN2 is one of three types of internal repeats which combine to form larger domains within fibronectin. Fibronectin, a plasma protein that binds cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin, usually exists as a dimer in plasma and as an insoluble multimer in extracellular matrices. Dimers of nearly identical subunits are linked by a disulfide bond close to their C-terminus. Fibronectin is composed of 3 types of modules, FN1,FN2 and FN3. The collagen binding domain contains four FN1 and two FN2 repeats. Pssm-ID: 238019 Cd Length: 48 Bit Score: 85.43 E-value: 1.08e-20
|
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| ZnMc | smart00235 | Zinc-dependent metalloprotease; Neutral zinc metallopeptidases. This alignment represents a ... |
65-168 | 4.97e-20 | ||||||
Zinc-dependent metalloprotease; Neutral zinc metallopeptidases. This alignment represents a subset of known subfamilies. Highest similarity occurs in the HExxH zinc-binding site/ active site. Pssm-ID: 214576 [Multi-domain] Cd Length: 139 Bit Score: 86.64 E-value: 4.97e-20
|
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| FN2 | cd00062 | Fibronectin Type II domain: FN2 is one of three types of internal repeats which combine to ... |
177-224 | 8.51e-20 | ||||||
Fibronectin Type II domain: FN2 is one of three types of internal repeats which combine to form larger domains within fibronectin. Fibronectin, a plasma protein that binds cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin, usually exists as a dimer in plasma and as an insoluble multimer in extracellular matrices. Dimers of nearly identical subunits are linked by a disulfide bond close to their C-terminus. Fibronectin is composed of 3 types of modules, FN1,FN2 and FN3. The collagen binding domain contains four FN1 and two FN2 repeats. Pssm-ID: 238019 Cd Length: 48 Bit Score: 82.74 E-value: 8.51e-20
|
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| fn2 | pfam00040 | Fibronectin type II domain; |
299-340 | 1.05e-18 | ||||||
Fibronectin type II domain; Pssm-ID: 459645 Cd Length: 42 Bit Score: 79.54 E-value: 1.05e-18
|
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| fn2 | pfam00040 | Fibronectin type II domain; |
183-224 | 1.33e-18 | ||||||
Fibronectin type II domain; Pssm-ID: 459645 Cd Length: 42 Bit Score: 79.15 E-value: 1.33e-18
|
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| fn2 | pfam00040 | Fibronectin type II domain; |
241-282 | 3.29e-18 | ||||||
Fibronectin type II domain; Pssm-ID: 459645 Cd Length: 42 Bit Score: 78.00 E-value: 3.29e-18
|
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| HX | smart00120 | Hemopexin-like repeats; Hemopexin is a heme-binding protein that transports heme to the liver. ... |
518-564 | 4.60e-10 | ||||||
Hemopexin-like repeats; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of metalloproteinases (TIMPs). Pssm-ID: 214524 [Multi-domain] Cd Length: 45 Bit Score: 54.94 E-value: 4.60e-10
|
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| Hemopexin | pfam00045 | Hemopexin; Hemopexin is a heme-binding protein that transports heme to the liver. ... |
518-564 | 3.48e-08 | ||||||
Hemopexin; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metallopeptidases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of metallopeptidases (TIMPs). Pssm-ID: 395000 [Multi-domain] Cd Length: 44 Bit Score: 49.87 E-value: 3.48e-08
|
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| ZnMc_MMP_like_1 | cd04279 | Zinc-dependent metalloprotease; MMP_like sub-family 1. A group of bacterial, archaeal, and ... |
337-396 | 1.16e-07 | ||||||
Zinc-dependent metalloprotease; MMP_like sub-family 1. A group of bacterial, archaeal, and fungal metalloproteinase domains similar to matrix metalloproteinases and astacin. Pssm-ID: 239806 [Multi-domain] Cd Length: 156 Bit Score: 51.69 E-value: 1.16e-07
|
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| ZnMc | cd00203 | Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major ... |
344-395 | 1.49e-06 | ||||||
Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major branches, the astacin-like proteases and the adamalysin/reprolysin-like proteases. Both branches have wide phylogenetic distribution, and contain sub-families, which are involved in vertebrate development and disease. Pssm-ID: 238124 [Multi-domain] Cd Length: 167 Bit Score: 48.67 E-value: 1.49e-06
|
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| Hemopexin | pfam00045 | Hemopexin; Hemopexin is a heme-binding protein that transports heme to the liver. ... |
470-513 | 4.12e-06 | ||||||
Hemopexin; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metallopeptidases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of metallopeptidases (TIMPs). Pssm-ID: 395000 [Multi-domain] Cd Length: 44 Bit Score: 43.71 E-value: 4.12e-06
|
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| HX | smart00120 | Hemopexin-like repeats; Hemopexin is a heme-binding protein that transports heme to the liver. ... |
470-513 | 3.37e-05 | ||||||
Hemopexin-like repeats; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of metalloproteinases (TIMPs). Pssm-ID: 214524 [Multi-domain] Cd Length: 45 Bit Score: 41.46 E-value: 3.37e-05
|
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| ZnMc_serralysin_like | cd04277 | Zinc-dependent metalloprotease, serralysin_like subfamily. Serralysins and related proteases ... |
314-396 | 9.97e-05 | ||||||
Zinc-dependent metalloprotease, serralysin_like subfamily. Serralysins and related proteases are important virulence factors in pathogenic bacteria. They may be secreted into the medium via a mechanism found in gram-negative bacteria, that does not require n-terminal signal sequences which are cleaved after the transmembrane translocation. A calcium-binding domain c-terminal to the metalloprotease domain, which contains multiple tandem repeats of a nine-residue motif including the pattern GGxGxD, and which forms a parallel beta roll may be involved in the translocation mechanism and/or substrate binding. Serralysin family members may have a broad spectrum of substrates each, including host immunoglobulins, complement proteins, cell matrix and cytoskeletal proteins, as well as antimicrobial peptides. Pssm-ID: 239804 [Multi-domain] Cd Length: 186 Bit Score: 43.56 E-value: 9.97e-05
|
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| HX | smart00120 | Hemopexin-like repeats; Hemopexin is a heme-binding protein that transports heme to the liver. ... |
425-467 | 4.06e-04 | ||||||
Hemopexin-like repeats; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of metalloproteinases (TIMPs). Pssm-ID: 214524 [Multi-domain] Cd Length: 45 Bit Score: 38.38 E-value: 4.06e-04
|
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| PG_binding_1 | pfam01471 | Putative peptidoglycan binding domain; This domain is composed of three alpha helices. This ... |
20-47 | 4.83e-04 | ||||||
Putative peptidoglycan binding domain; This domain is composed of three alpha helices. This domain is found at the N or C terminus of a variety of enzymes involved in bacterial cell wall degradation. This domain may have a general peptidoglycan binding function. This family is found N-terminal to the catalytic domain of matrixins. The domain is found to bind peptidoglycan experimentally. Pssm-ID: 460223 [Multi-domain] Cd Length: 57 Bit Score: 38.27 E-value: 4.83e-04
|
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| ZnMc_MMP_like | cd04268 | Zinc-dependent metalloprotease, MMP_like subfamily. This group contains matrix ... |
350-395 | 8.83e-04 | ||||||
Zinc-dependent metalloprotease, MMP_like subfamily. This group contains matrix metalloproteinases (MMPs), serralysins, and the astacin_like family of proteases. Pssm-ID: 239796 [Multi-domain] Cd Length: 165 Bit Score: 40.56 E-value: 8.83e-04
|
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| Hemopexin | pfam00045 | Hemopexin; Hemopexin is a heme-binding protein that transports heme to the liver. ... |
425-467 | 1.11e-03 | ||||||
Hemopexin; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metallopeptidases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of metallopeptidases (TIMPs). Pssm-ID: 395000 [Multi-domain] Cd Length: 44 Bit Score: 37.16 E-value: 1.11e-03
|
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| ZnMc_ADAM_like | cd04267 | Zinc-dependent metalloprotease, ADAM_like or reprolysin_like subgroup. The adamalysin_like or ... |
349-396 | 1.17e-03 | ||||||
Zinc-dependent metalloprotease, ADAM_like or reprolysin_like subgroup. The adamalysin_like or ADAM family of metalloproteases contains proteolytic domains from snake venoms, proteases from the mammalian reproductive tract, and the tumor necrosis factor alpha convertase, TACE. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. Pssm-ID: 239795 Cd Length: 192 Bit Score: 40.48 E-value: 1.17e-03
|
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| ZnMc | cd00203 | Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major ... |
74-172 | 2.07e-03 | ||||||
Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major branches, the astacin-like proteases and the adamalysin/reprolysin-like proteases. Both branches have wide phylogenetic distribution, and contain sub-families, which are involved in vertebrate development and disease. Pssm-ID: 238124 [Multi-domain] Cd Length: 167 Bit Score: 39.43 E-value: 2.07e-03
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| Blast search parameters | ||||
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