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Full Results
solute carrier family 12 member 4 isoform b [Homo sapiens]
Protein Classification
solute carrier family 12 protein ( domain architecture ID 11489985 )
solute carrier family 12 protein similar to Arabidopsis thaliana cation-chloride cotransporter 1, which mediates both potassium-chloride and sodium-chloride cotransports and is involved in plant development and Cl(-) homeostasis, or human kidney-specific Na-K-Cl symporter that mediates the transepithelial NaCl reabsorption in the thick ascending limb and plays an essential role in the urinary concentration and volume regulation
List of domain hits
Name
Accession
Description
Interval
E-value
2a30
TIGR00930 K-Cl cotransporter; [Transport and binding proteins, Other]
42-1079
0e+00
K-Cl cotransporter; [Transport and binding proteins, Other]
Pssm-ID: 273347 [Multi-domain]
Cd Length: 953
Bit Score: 1339.36
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 42 N HRESS P FLSPLEA S R G IDYYD RN LALF EE EL D IRP KV S SLLG K L VS YTN LT QG A KEHEEAE SG EGT RRRA - A E A PSM G T 120
Cdd:TIGR00930 1 N TVDAV P RIEHYRN S E G QGGPK RN RPSL EE LH D LLD KV V SLLG P L AD YTN NG QG M KEHEEAE DA EGT KEKP p A G A VKF G W 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 121 L MGV YL PCL Q NI F GVILFLRL T W M VG T AG VLQA LLI V L I CCC C T LL T AI SMSAIATNGVV PA GG S Y FM ISRSLGPEFGG A 200
Cdd:TIGR00930 81 V MGV LV PCL L NI W GVILFLRL S W I VG Q AG IGLS LLI I L L CCC V T TI T GL SMSAIATNGVV KG GG A Y YL ISRSLGPEFGG S 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 201 V GL C F YLGTTF A A AMY IL G AI E IL L T yiappaa IFYPS G a HDTSNATL N NM R V YGT IFLTFMTLVV F V G VKYV NK FAS LF 280
Cdd:TIGR00930 161 I GL I F AFANAV A V AMY VV G FA E TV L D ------- LLREN G - SKIMVDPI N DI R I YGT VTVVVLLGIS F A G MEWE NK AQV LF 232
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 281 L AC V II SIL S I YA G G I KSI FD P P VFPVCM LGN RTL S RD qfdicaktavvdnetvatqlwsffchspnlttdscdpyfmln 360
Cdd:TIGR00930 233 L VI V LL SIL N I FV G T I IPA FD K P AKGFFG LGN EIF S EN ------------------------------------------ 270
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 361 nvt E IPGIPG AAA G vlqenlwsaylekgdivekhglpsadapslkeslplyvvadiats F TV L V GIFFPSVTGI M AG S N R 440
Cdd:TIGR00930 271 --- F IPGIPG PEG G --------------------------------------------- F FS L F GIFFPSVTGI L AG A N I 302
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 441 SGDL R D A QK S IP V GT I LAI I TT SL VY FS SVVLFGAC IEGVVLR DK YGDG V S --------------------- R NL V V GT L 499
Cdd:TIGR00930 303 SGDL K D P QK A IP K GT L LAI L TT TV VY LG SVVLFGAC VVRDATG DK NDTL V T nctsaacfsecahntcsyglm N NL Q V MS L 382
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 500 AW P S P WV I VI G S F FS T CGAG L Q SL TG APRL L QA IA KDNI I PFL RV FG H G K - V NGEP TW A L LLTA L IAE LG ILIA S L DMV A 578
Cdd:TIGR00930 383 VS P F P PL I TA G I F SA T LSSA L A SL VS APRL F QA LC KDNI Y PFL QF FG K G Y g K NGEP LR A Y LLTA F IAE GF ILIA E L NTI A 462
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 579 PI L S M FFL MC Y LFV N LA C AVQT LLR T P N WRPRFKYYHW A LS F LG M SLC L A L MF VS SW YY ALVAM L IA GMI YKY IE Y QGAE 658
Cdd:TIGR00930 463 PI I S N FFL AS Y ALI N FS C FHAS LLR S P G WRPRFKYYHW W LS L LG A SLC C A I MF LI SW WA ALVAM V IA LFL YKY VT Y KKPD 542
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 659 KE WG DGIRG LS L S A A R Y A LLRLEE GPP H T KNWRPQ L LVL LKLD edlh V KY P R LL T FASQ LKA GKGL T I V GSVIQG SF LE S 738
Cdd:TIGR00930 543 VN WG SSTQA LS Y S L A L Y S LLRLEE VED H V KNWRPQ C LVL TGPP ---- V CR P A LL D FASQ FTK GKGL M I C GSVIQG PR LE C 618
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 739 YG EAQAAE QT I KNMM E IE KVK G F CQ VVVA SKV REG LA HLIQ SC GLG G M RH N SV V L G WPYG WRQ S E d PRAW K T F I DTVRCT 818
Cdd:TIGR00930 619 VK EAQAAE AK I QTWL E KN KVK A F YA VVVA DDL REG VR HLIQ AS GLG R M KP N TL V M G YKKD WRQ A E - PRAW E T Y I GIIHDA 697
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 819 TA AHLA LL V PK N IAFY P SNH -------------------------------------- ERYLE G H IDVWW I V H DGG MLM L 860
Cdd:TIGR00930 698 FD AHLA VV V VR N SEGL P ISV lqvqeelendcsedsielndgkistqpdmhleastqfq KKQGK G T IDVWW L V D DGG LTL L 777
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 861 LP F LL RQH KVW R KC RM RIF TV AQ M DD N S I Q M KKD L A VF LY HL R LE AE H --- NS DI S A yt YER T LM ME QRSQ M L R QM RL T K 937
Cdd:TIGR00930 778 LP Y LL TTK KVW K KC KI RIF VG AQ K DD R S E Q E KKD M A TL LY KF R ID AE V ivv LM DI N A -- KPQ T ES ME AFEE M I R PF RL H K 855
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 938 TE RE REA qlv KD RH salrleslysdeedesavgadkiq MTWT RDKYM T E twdpshapdnf R EL vhikpd QSNVR RMHTA V 1017
Cdd:TIGR00930 856 TE KD REA --- KD PK ------------------------ MTWT KPWKI T D ----------- A EL ------ QSNVR KSYRQ V 891
1050 1060 1070 1080 1090 1100
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 225579061 1018 K LNE VIVTR S H DA R LV L L NM P G P PRN S EG DE N YM EF LEVL T E G L ER VLLVRG GG R E V I T I YS 1079
Cdd:TIGR00930 892 R LNE LLLEY S R DA A LV V L SL P V P RKG S IP DE L YM AW LEVL S E D L PP VLLVRG NH R N V L T F YS 953
Name
Accession
Description
Interval
E-value
2a30
TIGR00930 K-Cl cotransporter; [Transport and binding proteins, Other]
42-1079
0e+00
K-Cl cotransporter; [Transport and binding proteins, Other]
Pssm-ID: 273347 [Multi-domain]
Cd Length: 953
Bit Score: 1339.36
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 42 N HRESS P FLSPLEA S R G IDYYD RN LALF EE EL D IRP KV S SLLG K L VS YTN LT QG A KEHEEAE SG EGT RRRA - A E A PSM G T 120
Cdd:TIGR00930 1 N TVDAV P RIEHYRN S E G QGGPK RN RPSL EE LH D LLD KV V SLLG P L AD YTN NG QG M KEHEEAE DA EGT KEKP p A G A VKF G W 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 121 L MGV YL PCL Q NI F GVILFLRL T W M VG T AG VLQA LLI V L I CCC C T LL T AI SMSAIATNGVV PA GG S Y FM ISRSLGPEFGG A 200
Cdd:TIGR00930 81 V MGV LV PCL L NI W GVILFLRL S W I VG Q AG IGLS LLI I L L CCC V T TI T GL SMSAIATNGVV KG GG A Y YL ISRSLGPEFGG S 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 201 V GL C F YLGTTF A A AMY IL G AI E IL L T yiappaa IFYPS G a HDTSNATL N NM R V YGT IFLTFMTLVV F V G VKYV NK FAS LF 280
Cdd:TIGR00930 161 I GL I F AFANAV A V AMY VV G FA E TV L D ------- LLREN G - SKIMVDPI N DI R I YGT VTVVVLLGIS F A G MEWE NK AQV LF 232
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 281 L AC V II SIL S I YA G G I KSI FD P P VFPVCM LGN RTL S RD qfdicaktavvdnetvatqlwsffchspnlttdscdpyfmln 360
Cdd:TIGR00930 233 L VI V LL SIL N I FV G T I IPA FD K P AKGFFG LGN EIF S EN ------------------------------------------ 270
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 361 nvt E IPGIPG AAA G vlqenlwsaylekgdivekhglpsadapslkeslplyvvadiats F TV L V GIFFPSVTGI M AG S N R 440
Cdd:TIGR00930 271 --- F IPGIPG PEG G --------------------------------------------- F FS L F GIFFPSVTGI L AG A N I 302
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 441 SGDL R D A QK S IP V GT I LAI I TT SL VY FS SVVLFGAC IEGVVLR DK YGDG V S --------------------- R NL V V GT L 499
Cdd:TIGR00930 303 SGDL K D P QK A IP K GT L LAI L TT TV VY LG SVVLFGAC VVRDATG DK NDTL V T nctsaacfsecahntcsyglm N NL Q V MS L 382
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 500 AW P S P WV I VI G S F FS T CGAG L Q SL TG APRL L QA IA KDNI I PFL RV FG H G K - V NGEP TW A L LLTA L IAE LG ILIA S L DMV A 578
Cdd:TIGR00930 383 VS P F P PL I TA G I F SA T LSSA L A SL VS APRL F QA LC KDNI Y PFL QF FG K G Y g K NGEP LR A Y LLTA F IAE GF ILIA E L NTI A 462
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 579 PI L S M FFL MC Y LFV N LA C AVQT LLR T P N WRPRFKYYHW A LS F LG M SLC L A L MF VS SW YY ALVAM L IA GMI YKY IE Y QGAE 658
Cdd:TIGR00930 463 PI I S N FFL AS Y ALI N FS C FHAS LLR S P G WRPRFKYYHW W LS L LG A SLC C A I MF LI SW WA ALVAM V IA LFL YKY VT Y KKPD 542
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 659 KE WG DGIRG LS L S A A R Y A LLRLEE GPP H T KNWRPQ L LVL LKLD edlh V KY P R LL T FASQ LKA GKGL T I V GSVIQG SF LE S 738
Cdd:TIGR00930 543 VN WG SSTQA LS Y S L A L Y S LLRLEE VED H V KNWRPQ C LVL TGPP ---- V CR P A LL D FASQ FTK GKGL M I C GSVIQG PR LE C 618
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 739 YG EAQAAE QT I KNMM E IE KVK G F CQ VVVA SKV REG LA HLIQ SC GLG G M RH N SV V L G WPYG WRQ S E d PRAW K T F I DTVRCT 818
Cdd:TIGR00930 619 VK EAQAAE AK I QTWL E KN KVK A F YA VVVA DDL REG VR HLIQ AS GLG R M KP N TL V M G YKKD WRQ A E - PRAW E T Y I GIIHDA 697
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 819 TA AHLA LL V PK N IAFY P SNH -------------------------------------- ERYLE G H IDVWW I V H DGG MLM L 860
Cdd:TIGR00930 698 FD AHLA VV V VR N SEGL P ISV lqvqeelendcsedsielndgkistqpdmhleastqfq KKQGK G T IDVWW L V D DGG LTL L 777
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 861 LP F LL RQH KVW R KC RM RIF TV AQ M DD N S I Q M KKD L A VF LY HL R LE AE H --- NS DI S A yt YER T LM ME QRSQ M L R QM RL T K 937
Cdd:TIGR00930 778 LP Y LL TTK KVW K KC KI RIF VG AQ K DD R S E Q E KKD M A TL LY KF R ID AE V ivv LM DI N A -- KPQ T ES ME AFEE M I R PF RL H K 855
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 938 TE RE REA qlv KD RH salrleslysdeedesavgadkiq MTWT RDKYM T E twdpshapdnf R EL vhikpd QSNVR RMHTA V 1017
Cdd:TIGR00930 856 TE KD REA --- KD PK ------------------------ MTWT KPWKI T D ----------- A EL ------ QSNVR KSYRQ V 891
1050 1060 1070 1080 1090 1100
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 225579061 1018 K LNE VIVTR S H DA R LV L L NM P G P PRN S EG DE N YM EF LEVL T E G L ER VLLVRG GG R E V I T I YS 1079
Cdd:TIGR00930 892 R LNE LLLEY S R DA A LV V L SL P V P RKG S IP DE L YM AW LEVL S E D L PP VLLVRG NH R N V L T F YS 953
AA_permease
pfam00324 Amino acid permease;
123-695
4.41e-51
Amino acid permease;
Pssm-ID: 366028 [Multi-domain]
Cd Length: 467
Bit Score: 187.53
E-value: 4.41e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 123 G V YLPC L QNIF G VI LF LRLTWMV G T AG VLQ ALL IV LI CCCCTL L TAI S MSA I A TNG V V p A GG S Y FMI SR S LGP EF G G A V G 202
Cdd:pfam00324 1 H V QMIA L GGVI G TG LF VGSGSVL G Q AG PAG ALL GY LI SGVVIF L VML S LGE I S TNG P V - S GG F Y TYA SR F LGP SL G F A T G 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 203 L -- CFYLG T TF A AA myi L G A IE IL LTYIAPPAA I F Y psgahdtsnatlnn MR V Y G TI FL TFM T LVVF VGVK YVNKFASL F 280
Cdd:pfam00324 80 W ny WLSWI T VL A LE --- L T A AS IL IQFWELVPD I P Y -------------- LW V W G AV FL VLL T IINL VGVK WYGEAEFW F 142
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 281 LACV II S I LSIYAG GI KSIFDP pvfpvcmlgnrtlsrdqfdicaktavvdnetvatqlwsffchspnlttdscdpyfmln 360
Cdd:pfam00324 143 ALIK II A I IGFIIV GI ILLSGG ---------------------------------------------------------- 164
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 361 nvteipgip GAAA G VLQEN L WSAYLEK gdivekhglpsadapslkeslpl YVVADIATS F TVLVG I F F PSV TGI MAGSNR 440
Cdd:pfam00324 165 --------- NPND G AIFRY L GDNGGKN ----------------------- NFPPGFGKG F ISVFV I A F FAF TGI ELVGIA 212
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 441 S G DLRDAQ KSIP VGTILA I ITTSLV Y FS S VVLF G ACIEGVVLRDKYGDGVSRNLV V ------ G TLAWPS pw V I VIGSFFS 514
Cdd:pfam00324 213 A G EVKNPE KSIP KAILQV I WRITIF Y IL S LLAI G LLVPWNDPGLLNDSASAASPF V iffkfl G ISGLAP -- L I NAVILTA 290
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 515 TCG A GLQ SL TGAP R L L QAI A K D NII P F lr VFGHGKVN G E P TW A L L LTAL I AE L GI L I ASL dm VAP I LSM F F L MCYLFVN L 594
Cdd:pfam00324 291 ALS A ANS SL YSGS R M L YSL A R D GLA P K -- FLKKVDKR G V P LR A I L VSMV I SL L AL L L ASL -- NPA I VFN F L L AISGLSG L 366
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 595 ACAVQTL L RTPNW R PR FKY YHWALSF L GMSLC L ALMF V SSWYY A LVAM LI AGMI Y KYIEYQ G AE K E WG D G IRGLSLSAAR 674
Cdd:pfam00324 367 IVWGLIS L SHLRF R KA FKY QGRSIDE L PFKAP L GPLG V ILGLA A IIII LI IQFL Y AFLPVP G GP K N WG A G SFAAAYLIVL 446
570 580
....*....|....*....|.
gi 225579061 675 YA L LR L EEGPP H T KNW R PQLL 695
Cdd:pfam00324 447 LF L II L IGVKL H V KNW K PQLL 467
PotE
COG0531 Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
131-655
1.03e-33
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
Pssm-ID: 440297 [Multi-domain]
Cd Length: 438
Bit Score: 135.41
E-value: 1.03e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 131 N I F G VIL F LRLTWMV G T AG v LQ A L L IV LI CCCCT LL T A I S MSAI A TN gv V P - AGG S Y FMIS R S LGP EF G GAV G LCFY L GT 209
Cdd:COG0531 25 A I I G AGI F VLPGLAA G L AG - PA A I L AW LI AGLLA LL V A L S YAEL A SA -- F P r AGG A Y TYAR R A LGP LL G FLA G WALL L SY 101
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 210 TF A A A MYILGAIEI L ltyiappa AIFY P S G AHD tsnatlnnmr VYGTIFLTFM TL VVFV GVK YVN K FASLFLACVIISI L 289
Cdd:COG0531 102 VL A V A AVAVAFGGY L -------- SSLF P A G GSV ---------- LIALVLILLL TL LNLR GVK ESA K VNNILTVLKLLVL L 163
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 290 SIYAG G I ksifdppvfpvcmlgnrtlsrdqfdicaktavvdnetvatqlwsffchspnlttdscd PY F MLN N V T EIPGIP 369
Cdd:COG0531 164 LFIVV G L ---------------------------------------------------------- FA F DPA N F T PFLPAG 185
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 370 G AAA GV lqenlwsaylekgdivekhglpsadapslkeslplyvvadiats FTV L VGI FF p SV TG IM A GS N RSGDLRDAQK 449
Cdd:COG0531 186 G GLS GV -------------------------------------------- LAA L ALA FF - AF TG FE A IA N LAEEAKNPKR 220
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 450 S IP VGT IL AIITTSLV Y FSSVVLFG acie GVV LR D KYGDGVSRNLVVGTLAWPSP -- WV I VI G SFF S TC GA GLQ S LT GA P 527
Cdd:COG0531 221 N IP RAI IL SLLIVGVL Y ILVSLALT ---- GVV PY D ELAASGAPLADAAEAVFGPW ga IL I AL G ALL S LL GA LNA S IL GA S 296
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 528 RLL Q A I A K D NII P fl R VF GH - GKVN G E P TW A L LLT AL IA E L GI L I -- AS LDMV A PIL S MFF L MC YL F V N LA CA V Q t LL R T 604
Cdd:COG0531 297 RLL Y A M A R D GLL P -- K VF AK v HPRF G T P VN A I LLT GV IA L L LL L L ga AS FTAL A SLA S VGV L LA YL L V A LA VI V L - RR R R 373
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....
gi 225579061 605 P NWRPR F KYYHWALSF LG MS LCL A L MFVS --- SWYYA LV AML I AGMI Y KYIEYQ 655
Cdd:COG0531 374 P DLPRP F RVPLPLIPI LG IL LCL F L LYLL gpg ALLIG LV LLA I GLLL Y LLYRRR 427
Name
Accession
Description
Interval
E-value
2a30
TIGR00930 K-Cl cotransporter; [Transport and binding proteins, Other]
42-1079
0e+00
K-Cl cotransporter; [Transport and binding proteins, Other]
Pssm-ID: 273347 [Multi-domain]
Cd Length: 953
Bit Score: 1339.36
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 42 N HRESS P FLSPLEA S R G IDYYD RN LALF EE EL D IRP KV S SLLG K L VS YTN LT QG A KEHEEAE SG EGT RRRA - A E A PSM G T 120
Cdd:TIGR00930 1 N TVDAV P RIEHYRN S E G QGGPK RN RPSL EE LH D LLD KV V SLLG P L AD YTN NG QG M KEHEEAE DA EGT KEKP p A G A VKF G W 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 121 L MGV YL PCL Q NI F GVILFLRL T W M VG T AG VLQA LLI V L I CCC C T LL T AI SMSAIATNGVV PA GG S Y FM ISRSLGPEFGG A 200
Cdd:TIGR00930 81 V MGV LV PCL L NI W GVILFLRL S W I VG Q AG IGLS LLI I L L CCC V T TI T GL SMSAIATNGVV KG GG A Y YL ISRSLGPEFGG S 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 201 V GL C F YLGTTF A A AMY IL G AI E IL L T yiappaa IFYPS G a HDTSNATL N NM R V YGT IFLTFMTLVV F V G VKYV NK FAS LF 280
Cdd:TIGR00930 161 I GL I F AFANAV A V AMY VV G FA E TV L D ------- LLREN G - SKIMVDPI N DI R I YGT VTVVVLLGIS F A G MEWE NK AQV LF 232
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 281 L AC V II SIL S I YA G G I KSI FD P P VFPVCM LGN RTL S RD qfdicaktavvdnetvatqlwsffchspnlttdscdpyfmln 360
Cdd:TIGR00930 233 L VI V LL SIL N I FV G T I IPA FD K P AKGFFG LGN EIF S EN ------------------------------------------ 270
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 361 nvt E IPGIPG AAA G vlqenlwsaylekgdivekhglpsadapslkeslplyvvadiats F TV L V GIFFPSVTGI M AG S N R 440
Cdd:TIGR00930 271 --- F IPGIPG PEG G --------------------------------------------- F FS L F GIFFPSVTGI L AG A N I 302
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 441 SGDL R D A QK S IP V GT I LAI I TT SL VY FS SVVLFGAC IEGVVLR DK YGDG V S --------------------- R NL V V GT L 499
Cdd:TIGR00930 303 SGDL K D P QK A IP K GT L LAI L TT TV VY LG SVVLFGAC VVRDATG DK NDTL V T nctsaacfsecahntcsyglm N NL Q V MS L 382
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 500 AW P S P WV I VI G S F FS T CGAG L Q SL TG APRL L QA IA KDNI I PFL RV FG H G K - V NGEP TW A L LLTA L IAE LG ILIA S L DMV A 578
Cdd:TIGR00930 383 VS P F P PL I TA G I F SA T LSSA L A SL VS APRL F QA LC KDNI Y PFL QF FG K G Y g K NGEP LR A Y LLTA F IAE GF ILIA E L NTI A 462
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 579 PI L S M FFL MC Y LFV N LA C AVQT LLR T P N WRPRFKYYHW A LS F LG M SLC L A L MF VS SW YY ALVAM L IA GMI YKY IE Y QGAE 658
Cdd:TIGR00930 463 PI I S N FFL AS Y ALI N FS C FHAS LLR S P G WRPRFKYYHW W LS L LG A SLC C A I MF LI SW WA ALVAM V IA LFL YKY VT Y KKPD 542
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 659 KE WG DGIRG LS L S A A R Y A LLRLEE GPP H T KNWRPQ L LVL LKLD edlh V KY P R LL T FASQ LKA GKGL T I V GSVIQG SF LE S 738
Cdd:TIGR00930 543 VN WG SSTQA LS Y S L A L Y S LLRLEE VED H V KNWRPQ C LVL TGPP ---- V CR P A LL D FASQ FTK GKGL M I C GSVIQG PR LE C 618
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 739 YG EAQAAE QT I KNMM E IE KVK G F CQ VVVA SKV REG LA HLIQ SC GLG G M RH N SV V L G WPYG WRQ S E d PRAW K T F I DTVRCT 818
Cdd:TIGR00930 619 VK EAQAAE AK I QTWL E KN KVK A F YA VVVA DDL REG VR HLIQ AS GLG R M KP N TL V M G YKKD WRQ A E - PRAW E T Y I GIIHDA 697
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 819 TA AHLA LL V PK N IAFY P SNH -------------------------------------- ERYLE G H IDVWW I V H DGG MLM L 860
Cdd:TIGR00930 698 FD AHLA VV V VR N SEGL P ISV lqvqeelendcsedsielndgkistqpdmhleastqfq KKQGK G T IDVWW L V D DGG LTL L 777
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 861 LP F LL RQH KVW R KC RM RIF TV AQ M DD N S I Q M KKD L A VF LY HL R LE AE H --- NS DI S A yt YER T LM ME QRSQ M L R QM RL T K 937
Cdd:TIGR00930 778 LP Y LL TTK KVW K KC KI RIF VG AQ K DD R S E Q E KKD M A TL LY KF R ID AE V ivv LM DI N A -- KPQ T ES ME AFEE M I R PF RL H K 855
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 938 TE RE REA qlv KD RH salrleslysdeedesavgadkiq MTWT RDKYM T E twdpshapdnf R EL vhikpd QSNVR RMHTA V 1017
Cdd:TIGR00930 856 TE KD REA --- KD PK ------------------------ MTWT KPWKI T D ----------- A EL ------ QSNVR KSYRQ V 891
1050 1060 1070 1080 1090 1100
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 225579061 1018 K LNE VIVTR S H DA R LV L L NM P G P PRN S EG DE N YM EF LEVL T E G L ER VLLVRG GG R E V I T I YS 1079
Cdd:TIGR00930 892 R LNE LLLEY S R DA A LV V L SL P V P RKG S IP DE L YM AW LEVL S E D L PP VLLVRG NH R N V L T F YS 953
AA_permease
pfam00324 Amino acid permease;
123-695
4.41e-51
Amino acid permease;
Pssm-ID: 366028 [Multi-domain]
Cd Length: 467
Bit Score: 187.53
E-value: 4.41e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 123 G V YLPC L QNIF G VI LF LRLTWMV G T AG VLQ ALL IV LI CCCCTL L TAI S MSA I A TNG V V p A GG S Y FMI SR S LGP EF G G A V G 202
Cdd:pfam00324 1 H V QMIA L GGVI G TG LF VGSGSVL G Q AG PAG ALL GY LI SGVVIF L VML S LGE I S TNG P V - S GG F Y TYA SR F LGP SL G F A T G 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 203 L -- CFYLG T TF A AA myi L G A IE IL LTYIAPPAA I F Y psgahdtsnatlnn MR V Y G TI FL TFM T LVVF VGVK YVNKFASL F 280
Cdd:pfam00324 80 W ny WLSWI T VL A LE --- L T A AS IL IQFWELVPD I P Y -------------- LW V W G AV FL VLL T IINL VGVK WYGEAEFW F 142
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 281 LACV II S I LSIYAG GI KSIFDP pvfpvcmlgnrtlsrdqfdicaktavvdnetvatqlwsffchspnlttdscdpyfmln 360
Cdd:pfam00324 143 ALIK II A I IGFIIV GI ILLSGG ---------------------------------------------------------- 164
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 361 nvteipgip GAAA G VLQEN L WSAYLEK gdivekhglpsadapslkeslpl YVVADIATS F TVLVG I F F PSV TGI MAGSNR 440
Cdd:pfam00324 165 --------- NPND G AIFRY L GDNGGKN ----------------------- NFPPGFGKG F ISVFV I A F FAF TGI ELVGIA 212
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 441 S G DLRDAQ KSIP VGTILA I ITTSLV Y FS S VVLF G ACIEGVVLRDKYGDGVSRNLV V ------ G TLAWPS pw V I VIGSFFS 514
Cdd:pfam00324 213 A G EVKNPE KSIP KAILQV I WRITIF Y IL S LLAI G LLVPWNDPGLLNDSASAASPF V iffkfl G ISGLAP -- L I NAVILTA 290
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 515 TCG A GLQ SL TGAP R L L QAI A K D NII P F lr VFGHGKVN G E P TW A L L LTAL I AE L GI L I ASL dm VAP I LSM F F L MCYLFVN L 594
Cdd:pfam00324 291 ALS A ANS SL YSGS R M L YSL A R D GLA P K -- FLKKVDKR G V P LR A I L VSMV I SL L AL L L ASL -- NPA I VFN F L L AISGLSG L 366
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 595 ACAVQTL L RTPNW R PR FKY YHWALSF L GMSLC L ALMF V SSWYY A LVAM LI AGMI Y KYIEYQ G AE K E WG D G IRGLSLSAAR 674
Cdd:pfam00324 367 IVWGLIS L SHLRF R KA FKY QGRSIDE L PFKAP L GPLG V ILGLA A IIII LI IQFL Y AFLPVP G GP K N WG A G SFAAAYLIVL 446
570 580
....*....|....*....|.
gi 225579061 675 YA L LR L EEGPP H T KNW R PQLL 695
Cdd:pfam00324 447 LF L II L IGVKL H V KNW K PQLL 467
PotE
COG0531 Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
131-655
1.03e-33
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
Pssm-ID: 440297 [Multi-domain]
Cd Length: 438
Bit Score: 135.41
E-value: 1.03e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 131 N I F G VIL F LRLTWMV G T AG v LQ A L L IV LI CCCCT LL T A I S MSAI A TN gv V P - AGG S Y FMIS R S LGP EF G GAV G LCFY L GT 209
Cdd:COG0531 25 A I I G AGI F VLPGLAA G L AG - PA A I L AW LI AGLLA LL V A L S YAEL A SA -- F P r AGG A Y TYAR R A LGP LL G FLA G WALL L SY 101
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 210 TF A A A MYILGAIEI L ltyiappa AIFY P S G AHD tsnatlnnmr VYGTIFLTFM TL VVFV GVK YVN K FASLFLACVIISI L 289
Cdd:COG0531 102 VL A V A AVAVAFGGY L -------- SSLF P A G GSV ---------- LIALVLILLL TL LNLR GVK ESA K VNNILTVLKLLVL L 163
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 290 SIYAG G I ksifdppvfpvcmlgnrtlsrdqfdicaktavvdnetvatqlwsffchspnlttdscd PY F MLN N V T EIPGIP 369
Cdd:COG0531 164 LFIVV G L ---------------------------------------------------------- FA F DPA N F T PFLPAG 185
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 370 G AAA GV lqenlwsaylekgdivekhglpsadapslkeslplyvvadiats FTV L VGI FF p SV TG IM A GS N RSGDLRDAQK 449
Cdd:COG0531 186 G GLS GV -------------------------------------------- LAA L ALA FF - AF TG FE A IA N LAEEAKNPKR 220
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 450 S IP VGT IL AIITTSLV Y FSSVVLFG acie GVV LR D KYGDGVSRNLVVGTLAWPSP -- WV I VI G SFF S TC GA GLQ S LT GA P 527
Cdd:COG0531 221 N IP RAI IL SLLIVGVL Y ILVSLALT ---- GVV PY D ELAASGAPLADAAEAVFGPW ga IL I AL G ALL S LL GA LNA S IL GA S 296
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 528 RLL Q A I A K D NII P fl R VF GH - GKVN G E P TW A L LLT AL IA E L GI L I -- AS LDMV A PIL S MFF L MC YL F V N LA CA V Q t LL R T 604
Cdd:COG0531 297 RLL Y A M A R D GLL P -- K VF AK v HPRF G T P VN A I LLT GV IA L L LL L L ga AS FTAL A SLA S VGV L LA YL L V A LA VI V L - RR R R 373
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....
gi 225579061 605 P NWRPR F KYYHWALSF LG MS LCL A L MFVS --- SWYYA LV AML I AGMI Y KYIEYQ 655
Cdd:COG0531 374 P DLPRP F RVPLPLIPI LG IL LCL F L LYLL gpg ALLIG LV LLA I GLLL Y LLYRRR 427
SLC12
pfam03522 Solute carrier family 12;
709-1079
2.42e-23
Solute carrier family 12;
Pssm-ID: 460955
Cd Length: 414
Bit Score: 103.85
E-value: 2.42e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 709 P R L LT FA SQLKAGKG L T I V G S V IQ G SF le S YGEAQAAEQTIKNMMEIE K V K G F CQV V VASKV REG LAH L I Q SC GLG GMRH 788
Cdd:pfam03522 2 P A L VD FA HLITKNVS L M I C G H V VK G RL -- S QKLRSELQKKAYRWLRKR K I K A F YAL V DGDNL REG AQA L L Q AS GLG KLKP 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 789 N SVVL G WPYG WR QSE ----------------------------------------------------------------- 803
Cdd:pfam03522 80 N ILLM G YKSD WR TCD keeleeyfnvihdafdlqyavailrlpegldvshllqdqdteelglgdetnssyaeqsseeqsts 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 804 DPRAWKTFIDTVRCTTAAH L ALLV -------------------- P KN I AFYP SN HERY L E ----------- G H IDVWW IV 852
Cdd:pfam03522 160 NSKQDDDKSKLSKKDSNLS L SPDK stknpsgkdssksdklkkks P SI I LRTA SN EKEI L N nitqfqkkqkk G T IDVWW LY 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 853 H DGG MLM LLP FL L RQHKV W RK C RM R I F TVAQMD D NSIQMKKDL A VF L YHL R LEA ehn SD I saytyer T LMME qrsqmlrq 932
Cdd:pfam03522 240 D DGG LTL LLP YI L STRSK W SD C KL R V F ALGNRK D ELEEEQRNM A SL L SKF R IDY --- SD L ------- T VIPD -------- 301
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 933 mr L TK TERERE aqlv K DRHSA L r L E SLYSD E E D ESAVG A D KI qmtwtrdkym T ET wdpshapdnfr EL VHI K p DQS N vr R 1012
Cdd:pfam03522 302 -- I TK KPKKET ---- K KFFDE L - I E PFRLH E D D KEEES A E KI ---------- T DS ----------- EL EAL K - EKT N -- R 350
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 225579061 1013 M hta VK L N E VIVTR S H DA R L VLLNM P G P PRNSEGDEN YM EF LE V LT EG L ERV LLVRG GGRE V I T I YS 1079
Cdd:pfam03522 351 Q --- LR L R E LLLEH S S DA N L IVMTL P M P RKGTVSAPL YM AW LE T LT KD L PPF LLVRG NQTS V L T F YS 414
AA_permease_2
pfam13520 Amino acid permease;
395-652
1.55e-13
Amino acid permease;
Pssm-ID: 404414 [Multi-domain]
Cd Length: 427
Bit Score: 73.88
E-value: 1.55e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 395 GLPSADAPS L KESLPLYVVA D IATSFTVLVGIFFP S V TG IMAGS N R S G dl RDAQKSI P VGTILAI I TTSLV Y FSSVVL F G 474
Cdd:pfam13520 165 VTADGGGFN L LSGEWHTFFP D GWPGVFAGFLGVLW S F TG FESAA N V S E -- EVKKRNV P KAIFIGV I IVGVL Y ILVNIA F F 242
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 475 ACI -- EGVV L RDKY G DGVS --- RNLVVGTL A W pspw VI VI GSFF S TC GA GLQSLT GA P RLL Q A I A K D NII PF L R V F GHGK 549
Cdd:pfam13520 243 GVV pd DEIA L SSGL G QVAA llf QAVGGKWG A I ---- IV VI LLAL S LL GA VNTAIV GA S RLL Y A L A R D GVL PF S R F F AKVN 318
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579061 550 VN G E P TW A LL LTA LIAELGI L IAS L DMV A PI ---- LS MFFLMCYLFVNLACAV qt L LR TPNWRPRFKYYH W ALSFL G M s L 625
Cdd:pfam13520 319 KF G S P IR A II LTA ILSLILL L LFL L SPA A YN alls LS AYGYLLSYLLPIIGLL -- I LR KKRPDLGRIPGR W PVAIF G I - L 395
250 260
....*....|....*....|....*..
gi 225579061 626 CLALMF V SSWYYALVAMLIAGMI Y KY I 652
Cdd:pfam13520 396 FSLFLI V ALFFPPVGPATGSSLN Y AI I 422
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
