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Conserved domains on  [gi|229577111|ref|NP_001153429|]
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dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C isoform e [Mus musculus]

Protein Classification

calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1( domain architecture ID 10763433)

calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1 (PDE1) is a cyclic nucleotide phosphodiesterase with a dual specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PDEase_I pfam00233
3'5'-cyclic nucleotide phosphodiesterase;
199-427 3.03e-113

3'5'-cyclic nucleotide phosphodiesterase;


:

Pssm-ID: 459723  Cd Length: 238  Bit Score: 337.60  E-value: 3.03e-113
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577111  199 YHNLMHAADVTQTVHYLLYKTGVANWLTELEIFAIIFSAAIHDYEHTGTTNNFHIQTRSDPAILYNDRSVLENHHLSAAY 278
Cdd:pfam00233   1 YHNWRHAFDVTQTMYYLLKTGKLKEVLTDLEILALLIAALCHDVDHPGTNNAFLIKTKSPLAILYNDSSVLENHHCATAF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577111  279 RLLQeDEEMNILVNLSKDDWREFRTLVIEMVMATDMSCHFQQIKAMKTALQQ-------PEAIEKPKAL-SLMLHTADIS 350
Cdd:pfam00233  81 QILQ-DEECNIFSNLSDEEYKEVRKLIISLILATDMAKHFELLKKFKSLLESkktldflENEEDRRLLLlSMLIKAADIS 159

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 229577111  351 HPAKAWDLHHRWTMSLLEEFFRQGDREAELGLPFSPLCDR-KSTMVAQSQVGFIDFIVEPTFTVLTDMTEKiVSPLID 427
Cdd:pfam00233 160 NPTRPWEISKKWADLVAEEFFRQGDLEKELGLPVSPLMDReKKTSLPKSQIGFIDFIVLPLFEALAKLFPE-LQPLLD 236
PDEase_I_N pfam08499
3'5'-cyclic nucleotide phosphodiesterase N-terminal; This domain is found to the N-terminus of ...
 54-114 3.96e-35

3'5'-cyclic nucleotide phosphodiesterase N-terminal; This domain is found to the N-terminus of the calcium/calmodulin-dependent 3'5'-cyclic nucleotide phosphodiesterase domain (pfam00233).


:

Pssm-ID: 462497 [Multi-domain]  Cd Length: 61  Bit Score: 126.30  E-value: 3.96e-35
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 229577111   54 RLLDTEDELSDIQSDAVPSEVRDWLASTFTRQMGMMLRRSDEKPRFKSIVHAVQAGIFVER 114
Cdd:pfam08499   1 RLLDEEDELSEIQSDAVPSEVRDWLASTFTRQMAAHKRRSEEKPKFRSVAHAVQAGIFVER 61
PTZ00121 super family cl31754
MAEBL; Provisional
 515-600 3.66e-05

MAEBL; Provisional


The actual alignment was detected with superfamily member PTZ00121:

Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 47.06  E-value: 3.66e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577111  515 AEEKQKEMEAKSQAEQGTTSKGEKKTSGEAKSQVNGTRKGDNPRGKNSKGEKAGEKQQNGDLKDGKnKADKKDHSNTGNE 594
Cdd:PTZ00121 1466 AEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAE-EAKKADEAKKAEE 1544


                  ....*.
gi 229577111  595 SKKTDD 600
Cdd:PTZ00121 1545 KKKADE 1550
 
Name Accession Description Interval E-value
PDEase_I pfam00233
3'5'-cyclic nucleotide phosphodiesterase;
199-427 3.03e-113

3'5'-cyclic nucleotide phosphodiesterase;


Pssm-ID: 459723  Cd Length: 238  Bit Score: 337.60  E-value: 3.03e-113
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577111  199 YHNLMHAADVTQTVHYLLYKTGVANWLTELEIFAIIFSAAIHDYEHTGTTNNFHIQTRSDPAILYNDRSVLENHHLSAAY 278
Cdd:pfam00233   1 YHNWRHAFDVTQTMYYLLKTGKLKEVLTDLEILALLIAALCHDVDHPGTNNAFLIKTKSPLAILYNDSSVLENHHCATAF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577111  279 RLLQeDEEMNILVNLSKDDWREFRTLVIEMVMATDMSCHFQQIKAMKTALQQ-------PEAIEKPKAL-SLMLHTADIS 350
Cdd:pfam00233  81 QILQ-DEECNIFSNLSDEEYKEVRKLIISLILATDMAKHFELLKKFKSLLESkktldflENEEDRRLLLlSMLIKAADIS 159

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 229577111  351 HPAKAWDLHHRWTMSLLEEFFRQGDREAELGLPFSPLCDR-KSTMVAQSQVGFIDFIVEPTFTVLTDMTEKiVSPLID 427
Cdd:pfam00233 160 NPTRPWEISKKWADLVAEEFFRQGDLEKELGLPVSPLMDReKKTSLPKSQIGFIDFIVLPLFEALAKLFPE-LQPLLD 236
PDEase_I_N pfam08499
3'5'-cyclic nucleotide phosphodiesterase N-terminal; This domain is found to the N-terminus of ...
 54-114 3.96e-35

3'5'-cyclic nucleotide phosphodiesterase N-terminal; This domain is found to the N-terminus of the calcium/calmodulin-dependent 3'5'-cyclic nucleotide phosphodiesterase domain (pfam00233).


Pssm-ID: 462497 [Multi-domain]  Cd Length: 61  Bit Score: 126.30  E-value: 3.96e-35
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 229577111   54 RLLDTEDELSDIQSDAVPSEVRDWLASTFTRQMGMMLRRSDEKPRFKSIVHAVQAGIFVER 114
Cdd:pfam08499   1 RLLDEEDELSEIQSDAVPSEVRDWLASTFTRQMAAHKRRSEEKPKFRSVAHAVQAGIFVER 61
HDc cd00077
Metal dependent phosphohydrolases with conserved 'HD' motif
 199-371 3.47e-14

Metal dependent phosphohydrolases with conserved 'HD' motif


Pssm-ID: 238032 [Multi-domain]  Cd Length: 145  Bit Score: 70.06  E-value: 3.47e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577111 199 YHNLMHAADVTQTVHYLLYKTGvanwLTELEIFAIIFSAAIHDYEHTGTTNNFhiqtrsdpailYNDRSVLENHHLSAAY 278
Cdd:cd00077    1 EHRFEHSLRVAQLARRLAEELG----LSEEDIELLRLAALLHDIGKPGTPDAI-----------TEEESELEKDHAIVGA 65

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577111 279 RLLQEDEemnilvnlskddWREFRTLVIEMVMATDmSCHFQQIKAMKTALQqpEAIEKPKALSLMLHTADISHPAKA--W 356
Cdd:cd00077   66 EILRELL------------LEEVIKLIDELILAVD-ASHHERLDGLGYPDG--LKGEEITLEARIVKLADRLDALRRdsR 130

                        170
                 ....*....|....*
gi 229577111 357 DLHHRWTMSLLEEFF 371
Cdd:cd00077  131 EKRRRIAEEDLEELL 145
HDc smart00471
Metal dependent phosphohydrolases with conserved 'HD' motif; Includes eukaryotic cyclic ...
 197-362 1.31e-11

Metal dependent phosphohydrolases with conserved 'HD' motif; Includes eukaryotic cyclic nucleotide phosphodiesterases (PDEc). This profile/HMM does not detect HD homologues in bacterial glycine aminoacyl-tRNA synthetases (beta subunit).


Pssm-ID: 214679 [Multi-domain]  Cd Length: 124  Bit Score: 61.93  E-value: 1.31e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577111   197 NPYHNLMHAADVTQTVHYLLYKTGvanwltELEIFAIIFSAAIHDYEHTGTTNNFHIQTrsdpailyndrSVLENHHLSA 276
Cdd:smart00471   1 SDYHVFEHSLRVAQLAAALAEELG------LLDIELLLLAALLHDIGKPGTPDSFLVKT-----------SVLEDHHFIG 63

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577111   277 AYRLLQEDEEmNILVNLSKddwrefrtlviemvmaTDMSCHFQQIKAMKTALQQPEAiekpkalsLMLHTADISHPAKAW 356
Cdd:smart00471  64 AEILLEEEEP-RILEEILR----------------TAILSHHERPDGLRGEPITLEA--------RIVKVADRLDALRAD 118


                   ....*.
gi 229577111   357 DLHHRW 362
Cdd:smart00471 119 RRYRRV 124
PTZ00121 PTZ00121
MAEBL; Provisional
 515-600 3.66e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 47.06  E-value: 3.66e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577111  515 AEEKQKEMEAKSQAEQGTTSKGEKKTSGEAKSQVNGTRKGDNPRGKNSKGEKAGEKQQNGDLKDGKnKADKKDHSNTGNE 594
Cdd:PTZ00121 1466 AEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAE-EAKKADEAKKAEE 1544


                  ....*.
gi 229577111  595 SKKTDD 600
Cdd:PTZ00121 1545 KKKADE 1550
 
Name Accession Description Interval E-value
PDEase_I pfam00233
3'5'-cyclic nucleotide phosphodiesterase;
199-427 3.03e-113

3'5'-cyclic nucleotide phosphodiesterase;


Pssm-ID: 459723  Cd Length: 238  Bit Score: 337.60  E-value: 3.03e-113
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577111  199 YHNLMHAADVTQTVHYLLYKTGVANWLTELEIFAIIFSAAIHDYEHTGTTNNFHIQTRSDPAILYNDRSVLENHHLSAAY 278
Cdd:pfam00233   1 YHNWRHAFDVTQTMYYLLKTGKLKEVLTDLEILALLIAALCHDVDHPGTNNAFLIKTKSPLAILYNDSSVLENHHCATAF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577111  279 RLLQeDEEMNILVNLSKDDWREFRTLVIEMVMATDMSCHFQQIKAMKTALQQ-------PEAIEKPKAL-SLMLHTADIS 350
Cdd:pfam00233  81 QILQ-DEECNIFSNLSDEEYKEVRKLIISLILATDMAKHFELLKKFKSLLESkktldflENEEDRRLLLlSMLIKAADIS 159

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 229577111  351 HPAKAWDLHHRWTMSLLEEFFRQGDREAELGLPFSPLCDR-KSTMVAQSQVGFIDFIVEPTFTVLTDMTEKiVSPLID 427
Cdd:pfam00233 160 NPTRPWEISKKWADLVAEEFFRQGDLEKELGLPVSPLMDReKKTSLPKSQIGFIDFIVLPLFEALAKLFPE-LQPLLD 236
PDEase_I_N pfam08499
3'5'-cyclic nucleotide phosphodiesterase N-terminal; This domain is found to the N-terminus of ...
 54-114 3.96e-35

3'5'-cyclic nucleotide phosphodiesterase N-terminal; This domain is found to the N-terminus of the calcium/calmodulin-dependent 3'5'-cyclic nucleotide phosphodiesterase domain (pfam00233).


Pssm-ID: 462497 [Multi-domain]  Cd Length: 61  Bit Score: 126.30  E-value: 3.96e-35
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 229577111   54 RLLDTEDELSDIQSDAVPSEVRDWLASTFTRQMGMMLRRSDEKPRFKSIVHAVQAGIFVER 114
Cdd:pfam08499   1 RLLDEEDELSEIQSDAVPSEVRDWLASTFTRQMAAHKRRSEEKPKFRSVAHAVQAGIFVER 61
HDc cd00077
Metal dependent phosphohydrolases with conserved 'HD' motif
 199-371 3.47e-14

Metal dependent phosphohydrolases with conserved 'HD' motif


Pssm-ID: 238032 [Multi-domain]  Cd Length: 145  Bit Score: 70.06  E-value: 3.47e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577111 199 YHNLMHAADVTQTVHYLLYKTGvanwLTELEIFAIIFSAAIHDYEHTGTTNNFhiqtrsdpailYNDRSVLENHHLSAAY 278
Cdd:cd00077    1 EHRFEHSLRVAQLARRLAEELG----LSEEDIELLRLAALLHDIGKPGTPDAI-----------TEEESELEKDHAIVGA 65

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577111 279 RLLQEDEemnilvnlskddWREFRTLVIEMVMATDmSCHFQQIKAMKTALQqpEAIEKPKALSLMLHTADISHPAKA--W 356
Cdd:cd00077   66 EILRELL------------LEEVIKLIDELILAVD-ASHHERLDGLGYPDG--LKGEEITLEARIVKLADRLDALRRdsR 130

                        170
                 ....*....|....*
gi 229577111 357 DLHHRWTMSLLEEFF 371
Cdd:cd00077  131 EKRRRIAEEDLEELL 145
HDc smart00471
Metal dependent phosphohydrolases with conserved 'HD' motif; Includes eukaryotic cyclic ...
 197-362 1.31e-11

Metal dependent phosphohydrolases with conserved 'HD' motif; Includes eukaryotic cyclic nucleotide phosphodiesterases (PDEc). This profile/HMM does not detect HD homologues in bacterial glycine aminoacyl-tRNA synthetases (beta subunit).


Pssm-ID: 214679 [Multi-domain]  Cd Length: 124  Bit Score: 61.93  E-value: 1.31e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577111   197 NPYHNLMHAADVTQTVHYLLYKTGvanwltELEIFAIIFSAAIHDYEHTGTTNNFHIQTrsdpailyndrSVLENHHLSA 276
Cdd:smart00471   1 SDYHVFEHSLRVAQLAAALAEELG------LLDIELLLLAALLHDIGKPGTPDSFLVKT-----------SVLEDHHFIG 63

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577111   277 AYRLLQEDEEmNILVNLSKddwrefrtlviemvmaTDMSCHFQQIKAMKTALQQPEAiekpkalsLMLHTADISHPAKAW 356
Cdd:smart00471  64 AEILLEEEEP-RILEEILR----------------TAILSHHERPDGLRGEPITLEA--------RIVKVADRLDALRAD 118


                   ....*.
gi 229577111   357 DLHHRW 362
Cdd:smart00471 119 RRYRRV 124
PTZ00121 PTZ00121
MAEBL; Provisional
 515-600 3.66e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 47.06  E-value: 3.66e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577111  515 AEEKQKEMEAKSQAEQGTTSKGEKKTSGEAKSQVNGTRKGDNPRGKNSKGEKAGEKQQNGDLKDGKnKADKKDHSNTGNE 594
Cdd:PTZ00121 1466 AEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAE-EAKKADEAKKAEE 1544


                  ....*.
gi 229577111  595 SKKTDD 600
Cdd:PTZ00121 1545 KKKADE 1550
PTZ00121 PTZ00121
MAEBL; Provisional
 515-600 8.29e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 45.90  E-value: 8.29e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577111  515 AEEKQKEMEAKSQAEQGTTSKGEKKTSGEAKSQVNGTRKGDNPRGKNSKGEKAGEKQQNGDLKDGKNKADKK-DHSNTGN 593
Cdd:PTZ00121 1427 AEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKaDEAKKAA 1506


                  ....*..
gi 229577111  594 ESKKTDD 600
Cdd:PTZ00121 1507 EAKKKAD 1513
PTZ00121 PTZ00121
MAEBL; Provisional
 515-600 1.13e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 45.52  E-value: 1.13e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577111  515 AEEKQKEMEAKSQAEQGTTSKGEKKTSGEAKSQVNGTRKGDNPRGKNSKGEKAGEKQQNGDLKDGKNKAdKKDHSNTGNE 594
Cdd:PTZ00121 1298 AEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKA-EAAEKKKEEA 1376


                  ....*.
gi 229577111  595 SKKTDD 600
Cdd:PTZ00121 1377 KKKADA 1382
PTZ00121 PTZ00121
MAEBL; Provisional
 515-600 4.66e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 43.59  E-value: 4.66e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577111  515 AEEKQKEMEAKSQAEQGTTSKGEKKTSGEAKSQVNGTRKGDNPRGKNSKGEKAGEKQQNGDLKDGKNKADKKDHSNTGNE 594
Cdd:PTZ00121 1453 AEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEE 1532


                  ....*.
gi 229577111  595 SKKTDD 600
Cdd:PTZ00121 1533 AKKADE 1538
PTZ00121 PTZ00121
MAEBL; Provisional
 512-597 7.14e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 42.82  E-value: 7.14e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577111  512 RLAAEEKQKEMEAKSQAEQGTTSKGEKKTSGEAKSQVNGTRKGDNPRGKNSKGEKAGE-KQQNGDLKDGKNKADKKDHSN 590
Cdd:PTZ00121 1391 KKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEaKKKAEEAKKAEEAKKKAEEAK 1470


                  ....*..
gi 229577111  591 TGNESKK 597
Cdd:PTZ00121 1471 KADEAKK 1477
PTZ00121 PTZ00121
MAEBL; Provisional
 515-600 9.29e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 42.44  E-value: 9.29e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577111  515 AEEKQKEMEAKSQAEQGTTSKGEKKTSGEAKSQVNGTRKGDNPRGKNSKGEKAGEKQQNGDLKDGKNKADKK-DHSNTGN 593
Cdd:PTZ00121 1440 AEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKaDEAKKAE 1519


                  ....*..
gi 229577111  594 ESKKTDD 600
Cdd:PTZ00121 1520 EAKKADE 1526
PTZ00121 PTZ00121
MAEBL; Provisional
 515-600 1.42e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 42.05  E-value: 1.42e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577111  515 AEEKQKEMEAKSQAEQGTTSKGEKKTSGEAKSQVNGTRKGDNPRgKNSKGEKAGEKQQNGDLKDGKNKAdKKDHSNTGNE 594
Cdd:PTZ00121 1479 AEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAK-KADEAKKAEEAKKADEAKKAEEKK-KADELKKAEE 1556


                  ....*.
gi 229577111  595 SKKTDD 600
Cdd:PTZ00121 1557 LKKAEE 1562
PTZ00121 PTZ00121
MAEBL; Provisional
 515-600 1.85e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 41.67  E-value: 1.85e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577111  515 AEEKQKEMEAKSQAEQGTTSKGEKKTSGEAKSQVNGTRKGDNPRGKNSKGEKAGEKQQNGDLKDGKNKADKKdhsntGNE 594
Cdd:PTZ00121 1407 ADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKK-----AEE 1481


                  ....*.
gi 229577111  595 SKKTDD 600
Cdd:PTZ00121 1482 AKKADE 1487
PTZ00121 PTZ00121
MAEBL; Provisional
 515-600 2.67e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 40.89  E-value: 2.67e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577111  515 AEEKQKEMEAKSQAEQGTTSKGEKKTSGEAKSQVNGTRKGDNPRGKNSKGEKAGEKQQNGDLKDGKNKADKKdhsntGNE 594
Cdd:PTZ00121 1420 ADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKK-----AEE 1494


                  ....*.
gi 229577111  595 SKKTDD 600
Cdd:PTZ00121 1495 AKKKAD 1500
PTZ00372 PTZ00372
endonuclease 4-like protein; Provisional
 516-603 6.28e-03

endonuclease 4-like protein; Provisional


Pssm-ID: 240388  Cd Length: 413  Bit Score: 39.31  E-value: 6.28e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229577111 516 EEKQKEMEAKSQAEQGTTSKGEKKTSGEAKSQVNGTRKgdnprgKNSKGEKAGEKQQNgdlKDGKNKADKKDHSNTGNES 595
Cdd:PTZ00372  39 LSTFSEEENKVATTSTKKDKKEDKNNESKKKSEKKKKK------KKEKKEPKSEGETK---LGFKTPKKSKKTKKKPPKP 109


                 ....*...
gi 229577111 596 KKTDDPEE 603
Cdd:PTZ00372 110 KPNEDVDN 117
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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