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Conserved domains on  [gi|237757322|ref|NP_001153775|]
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complement factor H-related protein C isoform 2 precursor [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PHA02927 super family cl33700
secreted complement-binding protein; Provisional
 509-743 2.42e-22

secreted complement-binding protein; Provisional


The actual alignment was detected with superfamily member PHA02927:

Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 97.42  E-value: 2.42e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 509 ISCPPPPQIP------NTQVIETTVKYLDGEKLSVLCQDNYLTQD--PEEMMCKDGRWQSLPHCIEKiPCSQPPTIEHGS 580
Cdd:PHA02927  18 LSCCTIPSRPinmkfkNSVETDANANYNIGDTIEYLCLPGYRKQKmgPIYAKCTGTGWTLFNQCIKR-RCPSPRDIDNGQ 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 581 IKLPRTsekrrksiefsshEHGTTFSYVCDDGFRIPEENGVACYMGK-----WS-TPPRCVGLPCGPPPSIPLGTVSLEL 654
Cdd:PHA02927  97 LDIGGV-------------DFGSSITYSCNSGYQLIGESKSYCELGStgsmvWNpEAPICESVKCQSPPSISNGRHNGYE 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 655 ESYQHGEEVTYHCSTGFGIDGPALIKCEGGKWSDPPKCIKTDCDiLPTIENAIIRGKNKKSYRTGEQVTVRCQSPYQMNG 734
Cdd:PHA02927 164 DFYTDGSVVTYSCNSGYSLIGNSGVLCSGGEWSDPPTCQIVKCP-HPTISNGYLSSGFKRSYSYNDNVDFKCKYGYKLSG 242


                 ....*....
gi 237757322 735 SDTVTCING 743
Cdd:PHA02927 243 SSSSTCSPG 251
PHA02927 super family cl33700
secreted complement-binding protein; Provisional
 208-447 3.68e-20

secreted complement-binding protein; Provisional


The actual alignment was detected with superfamily member PHA02927:

Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 91.25  E-value: 3.68e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 208 CIKSC----ERPV---FENSVTKNNSTWFKLNDKLDYECLIGYEneyKHTKGSI--TCTYYGWSDTPSCYEIECSVP--I 276
Cdd:PHA02927  16 CVLSCctipSRPInmkFKNSVETDANANYNIGDTIEYLCLPGYR---KQKMGPIyaKCTGTGWTLFNQCIKRRCPSPrdI 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 277 LDRKLVVSprkeKYRVGDLLEFSCRSGHRVGPDSVQCYHFG------WSPSFPTCKGqvASCAQPPEIPNGEINGAKRVe 350
Cdd:PHA02927  93 DNGQLDIG----GVDFGSSITYSCNSGYQLIGESKSYCELGstgsmvWNPEAPICES--VKCQSPPSISNGRHNGYEDF- 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 351 YSHGEVVGYDCKPRFLLKGPNKIQCVDGMWTTLPVCveEERTCGDiPELEHGSVKFSVP-PYHHGDSVEFTCAETFTMIG 429
Cdd:PHA02927 166 YTDGSVVTYSCNSGYSLIGNSGVLCSGGEWSDPPTC--QIVKCPH-PTISNGYLSSGFKrSYSYNDNVDFKCKYGYKLSG 242

                        250       260
                 ....*....|....*....|
gi 237757322 430 LGSVFCLSGK-WT-QLPKCV 447
Cdd:PHA02927 243 SSSSTCSPGNtWQpELPKCV 262
PHA02927 super family cl33700
secreted complement-binding protein; Provisional
 634-860 5.91e-15

secreted complement-binding protein; Provisional


The actual alignment was detected with superfamily member PHA02927:

Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 75.84  E-value: 5.91e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 634 CVgLPCGPPPSIPLGTV---SLELES---YQHGEEVTYHCSTGFGID--GPALIKCEGGKWSDPPKCIKTDCDILPTIEN 705
Cdd:PHA02927  16 CV-LSCCTIPSRPINMKfknSVETDAnanYNIGDTIEYLCLPGYRKQkmGPIYAKCTGTGWTLFNQCIKRRCPSPRDIDN 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 706 AIIrgkNKKSYRTGEQVTVRCQSPYQMNGSDTVTCINGR-----WIGK-PVCKDSrgKCGPPPPIDNGDITSlslpeYEP 779
Cdd:PHA02927  95 GQL---DIGGVDFGSSITYSCNSGYQLIGESKSYCELGStgsmvWNPEaPICESV--KCQSPPSISNGRHNG-----YED 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 780 F----SSVDYQCQKYYLLKGKKTITCRNGKWSEPPTC-LHACIIPenimearKIILKWRHT--KNIYSHSgEDIEFECKY 852
Cdd:PHA02927 165 FytdgSVVTYSCNSGYSLIGNSGVLCSGGEWSDPPTCqIVKCPHP-------TISNGYLSSgfKRSYSYN-DNVDFKCKY 236


                 ....*...
gi 237757322 853 GYhKARGS 860
Cdd:PHA02927 237 GY-KLSGS 243
PHA02927 super family cl33700
secreted complement-binding protein; Provisional
 50-210 1.29e-11

secreted complement-binding protein; Provisional


The actual alignment was detected with superfamily member PHA02927:

Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 65.83  E-value: 1.29e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322  50 VSIGNKYSYKCDNGFSPpSGIFWDYLRCTVQG---WEPEVPCVR--KCVFH-YVENGQSAYWEKIYVQGQSLKVQCYNGY 123
Cdd:PHA02927 102 VDFGSSITYSCNSGYQL-IGESKSYCELGSTGsmvWNPEAPICEsvKCQSPpSISNGRHNGYEDFYTDGSVVTYSCNSGY 180

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 124 SLQnGQDTMTCTENGWSPPPKCIRIKTCSVSdieIENGFFSESF-RTYALNRETSYRCKQGYvtNTGETSGSITCLQNGW 202
Cdd:PHA02927 181 SLI-GNSGVLCSGGEWSDPPTCQIVKCPHPT---ISNGYLSSGFkRSYSYNDNVDFKCKYGY--KLSGSSSSTCSPGNTW 254


                 ....*....
gi 237757322 203 SPQ-PSCIK 210
Cdd:PHA02927 255 QPElPKCVR 263
 
Name Accession Description Interval E-value
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 509-743 2.42e-22

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 97.42  E-value: 2.42e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 509 ISCPPPPQIP------NTQVIETTVKYLDGEKLSVLCQDNYLTQD--PEEMMCKDGRWQSLPHCIEKiPCSQPPTIEHGS 580
Cdd:PHA02927  18 LSCCTIPSRPinmkfkNSVETDANANYNIGDTIEYLCLPGYRKQKmgPIYAKCTGTGWTLFNQCIKR-RCPSPRDIDNGQ 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 581 IKLPRTsekrrksiefsshEHGTTFSYVCDDGFRIPEENGVACYMGK-----WS-TPPRCVGLPCGPPPSIPLGTVSLEL 654
Cdd:PHA02927  97 LDIGGV-------------DFGSSITYSCNSGYQLIGESKSYCELGStgsmvWNpEAPICESVKCQSPPSISNGRHNGYE 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 655 ESYQHGEEVTYHCSTGFGIDGPALIKCEGGKWSDPPKCIKTDCDiLPTIENAIIRGKNKKSYRTGEQVTVRCQSPYQMNG 734
Cdd:PHA02927 164 DFYTDGSVVTYSCNSGYSLIGNSGVLCSGGEWSDPPTCQIVKCP-HPTISNGYLSSGFKRSYSYNDNVDFKCKYGYKLSG 242


                 ....*....
gi 237757322 735 SDTVTCING 743
Cdd:PHA02927 243 SSSSTCSPG 251
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 208-447 3.68e-20

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 91.25  E-value: 3.68e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 208 CIKSC----ERPV---FENSVTKNNSTWFKLNDKLDYECLIGYEneyKHTKGSI--TCTYYGWSDTPSCYEIECSVP--I 276
Cdd:PHA02927  16 CVLSCctipSRPInmkFKNSVETDANANYNIGDTIEYLCLPGYR---KQKMGPIyaKCTGTGWTLFNQCIKRRCPSPrdI 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 277 LDRKLVVSprkeKYRVGDLLEFSCRSGHRVGPDSVQCYHFG------WSPSFPTCKGqvASCAQPPEIPNGEINGAKRVe 350
Cdd:PHA02927  93 DNGQLDIG----GVDFGSSITYSCNSGYQLIGESKSYCELGstgsmvWNPEAPICES--VKCQSPPSISNGRHNGYEDF- 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 351 YSHGEVVGYDCKPRFLLKGPNKIQCVDGMWTTLPVCveEERTCGDiPELEHGSVKFSVP-PYHHGDSVEFTCAETFTMIG 429
Cdd:PHA02927 166 YTDGSVVTYSCNSGYSLIGNSGVLCSGGEWSDPPTC--QIVKCPH-PTISNGYLSSGFKrSYSYNDNVDFKCKYGYKLSG 242

                        250       260
                 ....*....|....*....|
gi 237757322 430 LGSVFCLSGK-WT-QLPKCV 447
Cdd:PHA02927 243 SSSSTCSPGNtWQpELPKCV 262
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 634-860 5.91e-15

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 75.84  E-value: 5.91e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 634 CVgLPCGPPPSIPLGTV---SLELES---YQHGEEVTYHCSTGFGID--GPALIKCEGGKWSDPPKCIKTDCDILPTIEN 705
Cdd:PHA02927  16 CV-LSCCTIPSRPINMKfknSVETDAnanYNIGDTIEYLCLPGYRKQkmGPIYAKCTGTGWTLFNQCIKRRCPSPRDIDN 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 706 AIIrgkNKKSYRTGEQVTVRCQSPYQMNGSDTVTCINGR-----WIGK-PVCKDSrgKCGPPPPIDNGDITSlslpeYEP 779
Cdd:PHA02927  95 GQL---DIGGVDFGSSITYSCNSGYQLIGESKSYCELGStgsmvWNPEaPICESV--KCQSPPSISNGRHNG-----YED 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 780 F----SSVDYQCQKYYLLKGKKTITCRNGKWSEPPTC-LHACIIPenimearKIILKWRHT--KNIYSHSgEDIEFECKY 852
Cdd:PHA02927 165 FytdgSVVTYSCNSGYSLIGNSGVLCSGGEWSDPPTCqIVKCPHP-------TISNGYLSSgfKRSYSYN-DNVDFKCKY 236


                 ....*...
gi 237757322 853 GYhKARGS 860
Cdd:PHA02927 237 GY-KLSGS 243
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 50-210 1.29e-11

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 65.83  E-value: 1.29e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322  50 VSIGNKYSYKCDNGFSPpSGIFWDYLRCTVQG---WEPEVPCVR--KCVFH-YVENGQSAYWEKIYVQGQSLKVQCYNGY 123
Cdd:PHA02927 102 VDFGSSITYSCNSGYQL-IGESKSYCELGSTGsmvWNPEAPICEsvKCQSPpSISNGRHNGYEDFYTDGSVVTYSCNSGY 180

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 124 SLQnGQDTMTCTENGWSPPPKCIRIKTCSVSdieIENGFFSESF-RTYALNRETSYRCKQGYvtNTGETSGSITCLQNGW 202
Cdd:PHA02927 181 SLI-GNSGVLCSGGEWSDPPTCQIVKCPHPT---ISNGYLSSGFkRSYSYNDNVDFKCKYGY--KLSGSSSSTCSPGNTW 254


                 ....*....
gi 237757322 203 SPQ-PSCIK 210
Cdd:PHA02927 255 QPElPKCVR 263
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 758-812 2.87e-10

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 56.70  E-value: 2.87e-10
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 237757322 758 CGPPPPIDNGDITSlSLPEYEPFSSVDYQCQKYYLLKGKKTITCR-NGKWS-EPPTC 812
Cdd:cd00033    1 CPPPPVPENGTVTG-SKGSYSYGSTVTYSCNEGYTLVGSSTITCTeNGGWSpPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 639-693 1.22e-09

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 54.78  E-value: 1.22e-09
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 237757322 639 CGPPPSIPLGTVSLELESYQHGEEVTYHCSTGFGIDGPALIKC-EGGKWSD-PPKCI 693
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCtENGGWSPpPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 639-692 8.73e-09

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 52.14  E-value: 8.73e-09
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 237757322   639 CGPPPSIPLGTVSLELESYQHGEEVTYHCSTGFGIDGPALIKC-EGGKWSDP-PKC 692
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITClENGTWSPPpPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 393-447 9.63e-09

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 52.08  E-value: 9.63e-09
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 237757322 393 CGDIPELEHGSVKFSVPPYHHGDSVEFTCAETFTMIGLGSVFCL-SGKWTQ-LPKCV 447
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTeNGGWSPpPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 758-812 1.75e-08

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 51.37  E-value: 1.75e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 237757322   758 CGPPPPIDNGDITSLSlPEYEPFSSVDYQCQKYYLLKGKKTITCR-NGKWS-EPPTC 812
Cdd:smart00032   1 CPPPPDIENGTVTSSS-GTYSYGDTVTYSCDPGYTLIGSSTITCLeNGTWSpPPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 393-446 8.81e-08

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 49.45  E-value: 8.81e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 237757322   393 CGDIPELEHGSVKFSVPPYHHGDSVEFTCAETFTMIGLGSVFCL-SGKWT-QLPKC 446
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLeNGTWSpPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
697-751 4.44e-07

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 47.49  E-value: 4.44e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 237757322  697 CDILPTIENAIIRGKnKKSYRTGEQVTVRCQSPYQMNGSDTVTCI-NGRWIGK-PVC 751
Cdd:pfam00084   1 CPPPPDIPNGKVSAT-KNEYNYGASVSYECDPGYRLVGSPTITCQeDGTWSPPfPEC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
272-325 2.31e-06

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 45.57  E-value: 2.31e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 237757322  272 CSVPILDRKLVVSPRKEKYRVGDLLEFSCRSGHR-VGPDSVQC-YHFGWSPSFPTC 325
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRlVGSPTITCqEDGTWSPPFPEC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
758-812 5.26e-06

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 44.41  E-value: 5.26e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 237757322  758 CGPPPPIDNGDITSLSlPEYEPFSSVDYQCQKYYLLKGKKTITCR-NGKWS-EPPTC 812
Cdd:pfam00084   1 CPPPPDIPNGKVSATK-NEYNYGASVSYECDPGYRLVGSPTITCQeDGTWSpPFPEC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 97-146 7.65e-06

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 43.99  E-value: 7.65e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 237757322  97 VENGQSAYWEKIYVQGQSLKVQCYNGYSLQnGQDTMTCTENG-WSP-PPKCI 146
Cdd:cd00033    7 PENGTVTGSKGSYSYGSTVTYSCNEGYTLV-GSSTITCTENGgWSPpPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 97-145 1.92e-05

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 42.90  E-value: 1.92e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|.
gi 237757322    97 VENGQSAYWEKIYVQGQSLKVQCYNGYSLQnGQDTMTCTENG-WSPP-PKC 145
Cdd:smart00032   7 IENGTVTSSSGTYSYGDTVTYSCDPGYTLI-GSSTITCLENGtWSPPpPTC 56
 
Name Accession Description Interval E-value
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 509-743 2.42e-22

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 97.42  E-value: 2.42e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 509 ISCPPPPQIP------NTQVIETTVKYLDGEKLSVLCQDNYLTQD--PEEMMCKDGRWQSLPHCIEKiPCSQPPTIEHGS 580
Cdd:PHA02927  18 LSCCTIPSRPinmkfkNSVETDANANYNIGDTIEYLCLPGYRKQKmgPIYAKCTGTGWTLFNQCIKR-RCPSPRDIDNGQ 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 581 IKLPRTsekrrksiefsshEHGTTFSYVCDDGFRIPEENGVACYMGK-----WS-TPPRCVGLPCGPPPSIPLGTVSLEL 654
Cdd:PHA02927  97 LDIGGV-------------DFGSSITYSCNSGYQLIGESKSYCELGStgsmvWNpEAPICESVKCQSPPSISNGRHNGYE 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 655 ESYQHGEEVTYHCSTGFGIDGPALIKCEGGKWSDPPKCIKTDCDiLPTIENAIIRGKNKKSYRTGEQVTVRCQSPYQMNG 734
Cdd:PHA02927 164 DFYTDGSVVTYSCNSGYSLIGNSGVLCSGGEWSDPPTCQIVKCP-HPTISNGYLSSGFKRSYSYNDNVDFKCKYGYKLSG 242


                 ....*....
gi 237757322 735 SDTVTCING 743
Cdd:PHA02927 243 SSSSTCSPG 251
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 208-447 3.68e-20

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 91.25  E-value: 3.68e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 208 CIKSC----ERPV---FENSVTKNNSTWFKLNDKLDYECLIGYEneyKHTKGSI--TCTYYGWSDTPSCYEIECSVP--I 276
Cdd:PHA02927  16 CVLSCctipSRPInmkFKNSVETDANANYNIGDTIEYLCLPGYR---KQKMGPIyaKCTGTGWTLFNQCIKRRCPSPrdI 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 277 LDRKLVVSprkeKYRVGDLLEFSCRSGHRVGPDSVQCYHFG------WSPSFPTCKGqvASCAQPPEIPNGEINGAKRVe 350
Cdd:PHA02927  93 DNGQLDIG----GVDFGSSITYSCNSGYQLIGESKSYCELGstgsmvWNPEAPICES--VKCQSPPSISNGRHNGYEDF- 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 351 YSHGEVVGYDCKPRFLLKGPNKIQCVDGMWTTLPVCveEERTCGDiPELEHGSVKFSVP-PYHHGDSVEFTCAETFTMIG 429
Cdd:PHA02927 166 YTDGSVVTYSCNSGYSLIGNSGVLCSGGEWSDPPTC--QIVKCPH-PTISNGYLSSGFKrSYSYNDNVDFKCKYGYKLSG 242

                        250       260
                 ....*....|....*....|
gi 237757322 430 LGSVFCLSGK-WT-QLPKCV 447
Cdd:PHA02927 243 SSSSTCSPGNtWQpELPKCV 262
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 602-813 6.32e-18

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 84.70  E-value: 6.32e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 602 GTTFSYVCDDGFRIPEENGV--ACYMGKWSTPPRCVGLPCGPPPSIPLGtvSLELESYQHGEEVTYHCSTGFGIDGPALI 679
Cdd:PHA02927  47 GDTIEYLCLPGYRKQKMGPIyaKCTGTGWTLFNQCIKRRCPSPRDIDNG--QLDIGGVDFGSSITYSCNSGYQLIGESKS 124

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 680 KCEGGK-----WS-DPPKCIKTDCDILPTIENAIIRGKNKkSYRTGEQVTVRCQSPYQMNGSDTVTCINGRWIGKPVCKD 753
Cdd:PHA02927 125 YCELGStgsmvWNpEAPICESVKCQSPPSISNGRHNGYED-FYTDGSVVTYSCNSGYSLIGNSGVLCSGGEWSDPPTCQI 203

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 237757322 754 SrgKCgPPPPIDNGDITSLSLPEYEPFSSVDYQCQKYYLLKGKKTITCRNGKWSEP--PTCL 813
Cdd:PHA02927 204 V--KC-PHPTISNGYLSSGFKRSYSYNDNVDFKCKYGYKLSGSSSSTCSPGNTWQPelPKCV 262
PHA02831 PHA02831
EEV host range protein; Provisional
 650-801 2.38e-15

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 76.95  E-value: 2.38e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 650 VSLELESYQHGEEVTYHCSTGFGidgPALIKCEGGKWSDPPKCI-KTDCDILPTIENAIIRGKNKKsYRTGEQVTVRCQ- 727
Cdd:PHA02831  33 DSYENKVYEENENLEYKCNNNFD---KVFVTCNNGSWSTKNMCIgKRNCKDPVTILNGYIKNKKDQ-YSFGDSVTYACKv 108

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 237757322 728 ---SPYQMNGSDTVTCINGRWIGK-PVCKDSRGKCgppPPIDNGDITSLSLPEYEPfSSVDYQCQKYYLLKGKKTITC 801
Cdd:PHA02831 109 nklEKYSIVGNETVKCINKQWVPKyPVCKLIRCKY---PALQNGFLNVFEKKFYYG-DIVNFKCKKGFILLGSSVSTC 182
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 515-773 3.47e-15

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 77.43  E-value: 3.47e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 515 PQIPNTQVIETTVKYLDGEKLSVLCQDNYLTQDPEEMmCKDGRWQSlphcieKIPCSQPPTIEHgsiklpRTSEKRRKSI 594
Cdd:PHA02954  24 PTMNNAKLTSTETSFNDKQKVTFTCDSGYYSLDPNAV-CETDKWKY------ENPCKKMCTVSD------YVSELYDKPL 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 595 efssHEHGTTFSYVCDDG---FRIPEENGVAcymgKWSTPPRCVGLPCgPPPSIPLGTVSLELESYQHGEEVTYHCSTGF 671
Cdd:PHA02954  91 ----YEVNSTITLICKDEtkyFRCEEKNGNT----SWNDTVTCPNAEC-QPLQLEHGSCQPVKEKYSFGEHITINCDVGY 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 672 GIDGPALIKCEGGKWSDPPKCiKTDCDIlPTIENAIIRGknkKSYRTGEQVTVRCQSPYQMNGSDTVTCINGRWIGK-PV 750
Cdd:PHA02954 162 EVIGASYISCTANSWNVIPSC-QQKCDI-PSLSNGLISG---STFSIGGVIHLSCKSGFTLTGSPSSTCIDGKWNPVlPI 236

                        250       260
                 ....*....|....*....|....*
gi 237757322 751 CKDSRGKCGP--PPPIDNGDITSLS 773
Cdd:PHA02954 237 CVRSNEEFDPvdDGPDDETDLSKLS 261
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 634-860 5.91e-15

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 75.84  E-value: 5.91e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 634 CVgLPCGPPPSIPLGTV---SLELES---YQHGEEVTYHCSTGFGID--GPALIKCEGGKWSDPPKCIKTDCDILPTIEN 705
Cdd:PHA02927  16 CV-LSCCTIPSRPINMKfknSVETDAnanYNIGDTIEYLCLPGYRKQkmGPIYAKCTGTGWTLFNQCIKRRCPSPRDIDN 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 706 AIIrgkNKKSYRTGEQVTVRCQSPYQMNGSDTVTCINGR-----WIGK-PVCKDSrgKCGPPPPIDNGDITSlslpeYEP 779
Cdd:PHA02927  95 GQL---DIGGVDFGSSITYSCNSGYQLIGESKSYCELGStgsmvWNPEaPICESV--KCQSPPSISNGRHNG-----YED 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 780 F----SSVDYQCQKYYLLKGKKTITCRNGKWSEPPTC-LHACIIPenimearKIILKWRHT--KNIYSHSgEDIEFECKY 852
Cdd:PHA02927 165 FytdgSVVTYSCNSGYSLIGNSGVLCSGGEWSDPPTCqIVKCPHP-------TISNGYLSSgfKRSYSYN-DNVDFKCKY 236


                 ....*...
gi 237757322 853 GYhKARGS 860
Cdd:PHA02927 237 GY-KLSGS 243
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 290-507 1.21e-13

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 71.99  E-value: 1.21e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 290 YRVGDLLEFSCRSGHR---VGPDSVQCYHFGWSpSFPTCKGQvaSCAQPPEIPNGEINGAKrVEYshGEVVGYDCKPRFL 366
Cdd:PHA02927  44 YNIGDTIEYLCLPGYRkqkMGPIYAKCTGTGWT-LFNQCIKR--RCPSPRDIDNGQLDIGG-VDF--GSSITYSCNSGYQ 117

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 367 LKGPNKIQCVDG-----MWT-TLPVCveEERTCGDIPELEHGSVKFSVPPYHHGDSVEFTCAETFTMIGLGSVFCLSGKW 440
Cdd:PHA02927 118 LIGESKSYCELGstgsmVWNpEAPIC--ESVKCQSPPSISNGRHNGYEDFYTDGSVVTYSCNSGYSLIGNSGVLCSGGEW 195

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 237757322 441 TQLPKCvatdQLEKCRVLKSTDIEAIKPKRKEFQHNSTMYYKCRDKQEY---EHSICINGK-WNPE-PNCIR 507
Cdd:PHA02927 196 SDPPTC----QIVKCPHPTISNGYLSSGFKRSYSYNDNVDFKCKYGYKLsgsSSSTCSPGNtWQPElPKCVR 263
PHA02831 PHA02831
EEV host range protein; Provisional
 593-754 4.26e-13

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 70.41  E-value: 4.26e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 593 SIEFSSHEHGTTFSYVCDDGFripEENGVACYMGKWSTPPRCVG-LPCGPPPSIPLGTVSLELESYQHGEEVTYHCSTG- 670
Cdd:PHA02831  34 SYENKVYEENENLEYKCNNNF---DKVFVTCNNGSWSTKNMCIGkRNCKDPVTILNGYIKNKKDQYSFGDSVTYACKVNk 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 671 ---FGIDGPALIKCEGGKW-SDPPKCIKTDCDiLPTIENAIIRGKNKKSYrTGEQVTVRCQSPYQMNGSDTVTC-INGRW 745
Cdd:PHA02831 111 lekYSIVGNETVKCINKQWvPKYPVCKLIRCK-YPALQNGFLNVFEKKFY-YGDIVNFKCKKGFILLGSSVSTCdINSIW 188

                        170
                 ....*....|.
gi 237757322 746 I-GKPVC-KDS 754
Cdd:PHA02831 189 YpGIPKCvKDK 199
PHA02831 PHA02831
EEV host range protein; Provisional
 217-390 1.90e-12

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 68.48  E-value: 1.90e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 217 FENSVTKNNSTwFKLNDKLDYECLIGYENEYkhtkgsITCTYYGWSDTPSCY-EIECSVPILDRKLVVSPRKEKYRVGDL 295
Cdd:PHA02831  29 YSNVDSYENKV-YEENENLEYKCNNNFDKVF------VTCNNGSWSTKNMCIgKRNCKDPVTILNGYIKNKKDQYSFGDS 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 296 LEFSCRSGHR-----VGPDSVQCYHFGWSPSFPTCKgqVASCaQPPEIPNGEINGAKRvEYSHGEVVGYDCKPRFLLKGP 370
Cdd:PHA02831 102 VTYACKVNKLekysiVGNETVKCINKQWVPKYPVCK--LIRC-KYPALQNGFLNVFEK-KFYYGDIVNFKCKKGFILLGS 177

                        170       180
                 ....*....|....*....|..
gi 237757322 371 NKIQC-VDGMWT-TLPVCVEEE 390
Cdd:PHA02831 178 SVSTCdINSIWYpGIPKCVKDK 199
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 50-210 1.29e-11

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 65.83  E-value: 1.29e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322  50 VSIGNKYSYKCDNGFSPpSGIFWDYLRCTVQG---WEPEVPCVR--KCVFH-YVENGQSAYWEKIYVQGQSLKVQCYNGY 123
Cdd:PHA02927 102 VDFGSSITYSCNSGYQL-IGESKSYCELGSTGsmvWNPEAPICEsvKCQSPpSISNGRHNGYEDFYTDGSVVTYSCNSGY 180

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 124 SLQnGQDTMTCTENGWSPPPKCIRIKTCSVSdieIENGFFSESF-RTYALNRETSYRCKQGYvtNTGETSGSITCLQNGW 202
Cdd:PHA02927 181 SLI-GNSGVLCSGGEWSDPPTCQIVKCPHPT---ISNGYLSSGFkRSYSYNDNVDFKCKYGY--KLSGSSSSTCSPGNTW 254


                 ....*....
gi 237757322 203 SPQ-PSCIK 210
Cdd:PHA02927 255 QPElPKCVR 263
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 98-325 2.21e-10

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 62.36  E-value: 2.21e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322  98 ENGQSAYWEKIYVQGQSLKVQCYNGYSLQN-GQDTMTCTENGWSPPPKCIRIKTCSVSDIEieNGFFSESFRTYAlnRET 176
Cdd:PHA02927  33 KNSVETDANANYNIGDTIEYLCLPGYRKQKmGPIYAKCTGTGWTLFNQCIKRRCPSPRDID--NGQLDIGGVDFG--SSI 108

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 177 SYRCKQGYVTnTGETSGSITCLQNG---WSPQ-PSC--IKSCERPVFENSVTKNNSTWFKLNDKLDYECLIGYEneyKHT 250
Cdd:PHA02927 109 TYSCNSGYQL-IGESKSYCELGSTGsmvWNPEaPICesVKCQSPPSISNGRHNGYEDFYTDGSVVTYSCNSGYS---LIG 184

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 237757322 251 KGSITCTYYGWSDTPSCYEIECSVPILDRKLVVSPRKEKYRVGDLLEFSCRSGHRV-GPDSVQCYHFG-WSPSFPTC 325
Cdd:PHA02927 185 NSGVLCSGGEWSDPPTCQIVKCPHPTISNGYLSSGFKRSYSYNDNVDFKCKYGYKLsGSSSSTCSPGNtWQPELPKC 261
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 758-812 2.87e-10

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 56.70  E-value: 2.87e-10
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 237757322 758 CGPPPPIDNGDITSlSLPEYEPFSSVDYQCQKYYLLKGKKTITCR-NGKWS-EPPTC 812
Cdd:cd00033    1 CPPPPVPENGTVTG-SKGSYSYGSTVTYSCNEGYTLVGSSTITCTeNGGWSpPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 639-693 1.22e-09

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 54.78  E-value: 1.22e-09
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 237757322 639 CGPPPSIPLGTVSLELESYQHGEEVTYHCSTGFGIDGPALIKC-EGGKWSD-PPKCI 693
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCtENGGWSPpPPTCE 57
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 411-635 1.79e-09

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 59.67  E-value: 1.79e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 411 YHHGDSVEFTCAETFTMIGLGSVF--CLSGKWTQLPKCVAtdqlEKCRVLKSTDIEAIKPKRKEFqhNSTMYYKCRDKQE 488
Cdd:PHA02927  44 YNIGDTIEYLCLPGYRKQKMGPIYakCTGTGWTLFNQCIK----RRCPSPRDIDNGQLDIGGVDF--GSSITYSCNSGYQ 117

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 489 Y---EHSICINGK-----WNPEPNCIRKISCPPPPQIPNTQVIETTVKYLDGEKLSVLCQDNYLTQDPEEMMCKDGRWQS 560
Cdd:PHA02927 118 LigeSKSYCELGStgsmvWNPEAPICESVKCQSPPSISNGRHNGYEDFYTDGSVVTYSCNSGYSLIGNSGVLCSGGEWSD 197

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 237757322 561 LPHC-IEKIPcsqPPTIEHGSIKlprTSEKRrksiefsSHEHGTTFSYVCDDGFRIPEENGVACYMGKWSTP--PRCV 635
Cdd:PHA02927 198 PPTCqIVKCP---HPTISNGYLS---SGFKR-------SYSYNDNVDFKCKYGYKLSGSSSSTCSPGNTWQPelPKCV 262
PHA02639 PHA02639
EEV host range protein; Provisional
 563-751 6.29e-09

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 58.14  E-value: 6.29e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 563 HCIEKIPCSQPPTIEHGSIklprtSEKRRKsiefssHEHGTTFSYVCDDGFRIPEENGVACYMGK----WST-PPRCVGL 637
Cdd:PHA02639  15 HGVKSIYCDKPDDISNGFI-----TELMEK------YEIGKLIEYTCNTDYALIGDRFRTCIKDKnnaiWSNkAPFCMLK 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 638 PCGPPPSIPLGTVSLELESYQHGEEVTYHCSTGFGID----GPALIKCEGGK-WS-DPPKCIKTDCDiLPTIENAIIRG- 710
Cdd:PHA02639  84 ECNDPPSIINGKIYNKREMYKVGDEIYYVCNEHKGVQyslvGNEKITCIQDKsWKpDPPICKMINCR-FPALQNGYINGi 162

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 237757322 711 -KNKKSYRTgEQVTVRCQSPYQMNGSDTVTC-INGRWIGK-PVC 751
Cdd:PHA02639 163 pSNKKFYYK-TRVGFSCKSGFDLVGEKYSTCnINATWFPSiPTC 205
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 639-692 8.73e-09

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 52.14  E-value: 8.73e-09
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 237757322   639 CGPPPSIPLGTVSLELESYQHGEEVTYHCSTGFGIDGPALIKC-EGGKWSDP-PKC 692
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITClENGTWSPPpPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 393-447 9.63e-09

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 52.08  E-value: 9.63e-09
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 237757322 393 CGDIPELEHGSVKFSVPPYHHGDSVEFTCAETFTMIGLGSVFCL-SGKWTQ-LPKCV 447
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTeNGGWSPpPPTCE 57
PHA02831 PHA02831
EEV host range protein; Provisional
 282-447 1.01e-08

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 57.31  E-value: 1.01e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 282 VVSPRKEKYRVGDLLEFSCRSGHrvgpDSV--QCYHFGWSPSfPTCKGQvASCAQPPEIPNGEINGaKRVEYSHGEVVGY 359
Cdd:PHA02831  32 VDSYENKVYEENENLEYKCNNNF----DKVfvTCNNGSWSTK-NMCIGK-RNCKDPVTILNGYIKN-KKDQYSFGDSVTY 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 360 DCK----PRFLLKGPNKIQCVDGMWT-TLPVCveEERTCgDIPELEHGSVKFSVPPYHHGDSVEFTCAETFTMIGLGSVF 434
Cdd:PHA02831 105 ACKvnklEKYSIVGNETVKCINKQWVpKYPVC--KLIRC-KYPALQNGFLNVFEKKFYYGDIVNFKCKKGFILLGSSVST 181

                        170
                 ....*....|....*
gi 237757322 435 C-LSGKWT-QLPKCV 447
Cdd:PHA02831 182 CdINSIWYpGIPKCV 196
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 211-451 1.33e-08

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 57.40  E-value: 1.33e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 211 SCERPVFENSVTKNNSTWFKLNDKLDYECLIGYENeykhTKGSITCTYYGWSDTPSCYEIeCSVPILDRKLVVSPRkekY 290
Cdd:PHA02954  20 TCTVPTMNNAKLTSTETSFNDKQKVTFTCDSGYYS----LDPNAVCETDKWKYENPCKKM-CTVSDYVSELYDKPL---Y 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 291 RVGDLLEFSCRSGHRVGPDSVQCYHFGWSPSFpTCKGqvASCaQPPEIPNGEINGAKRvEYSHGEVVGYDCKPRFLLKGP 370
Cdd:PHA02954  92 EVNSTITLICKDETKYFRCEEKNGNTSWNDTV-TCPN--AEC-QPLQLEHGSCQPVKE-KYSFGEHITINCDVGYEVIGA 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 371 NKIQCVDGMWTTLPVCveeERTCgDIPELEHGSVKFSVppYHHGDSVEFTCAETFTMIGLGSVFCLSGKWTQ-LPKCVAT 449
Cdd:PHA02954 167 SYISCTANSWNVIPSC---QQKC-DIPSLSNGLISGST--FSIGGVIHLSCKSGFTLTGSPSSTCIDGKWNPvLPICVRS 240


                 ..
gi 237757322 450 DQ 451
Cdd:PHA02954 241 NE 242
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 758-812 1.75e-08

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 51.37  E-value: 1.75e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 237757322   758 CGPPPPIDNGDITSLSlPEYEPFSSVDYQCQKYYLLKGKKTITCR-NGKWS-EPPTC 812
Cdd:smart00032   1 CPPPPDIENGTVTSSS-GTYSYGDTVTYSCDPGYTLIGSSTITCLeNGTWSpPPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 393-446 8.81e-08

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 49.45  E-value: 8.81e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 237757322   393 CGDIPELEHGSVKFSVPPYHHGDSVEFTCAETFTMIGLGSVFCL-SGKWT-QLPKC 446
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLeNGTWSpPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 332-387 1.01e-07

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 49.38  E-value: 1.01e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 237757322 332 CAQPPEIPNGEINGAKRvEYSHGEVVGYDCKPRFLLKGPNKIQCV-DGMWT-TLPVCV 387
Cdd:cd00033    1 CPPPPVPENGTVTGSKG-SYSYGSTVTYSCNEGYTLVGSSTITCTeNGGWSpPPPTCE 57
PHA02639 PHA02639
EEV host range protein; Provisional
 157-325 1.55e-07

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 53.90  E-value: 1.55e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 157 EIENGFFSESFRTYALNRETSYRCKQGYVTNTGETSGSITCLQNG-WSPQ-PSC-IKSC-ERPVFENSVTKNNSTWFKLN 232
Cdd:PHA02639  27 DISNGFITELMEKYEIGKLIEYTCNTDYALIGDRFRTCIKDKNNAiWSNKaPFCmLKECnDPPSIINGKIYNKREMYKVG 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 233 DKLDYECligyeNEYKHTKGS------ITCTY-YGWS-DTPSCYEIECSVPILDRKLVVS-PRKEKYRVGDLLEFSCRSG 303
Cdd:PHA02639 107 DEIYYVC-----NEHKGVQYSlvgnekITCIQdKSWKpDPPICKMINCRFPALQNGYINGiPSNKKFYYKTRVGFSCKSG 181

                        170       180
                 ....*....|....*....|....
gi 237757322 304 HR-VGPDSVQC-YHFGWSPSFPTC 325
Cdd:PHA02639 182 FDlVGEKYSTCnINATWFPSIPTC 205
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 697-752 3.34e-07

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 47.84  E-value: 3.34e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 237757322 697 CDILPTIENAIIRGKnKKSYRTGEQVTVRCQSPYQMNGSDTVTCI-NGRWIGK-PVCK 752
Cdd:cd00033    1 CPPPPVPENGTVTGS-KGSYSYGSTVTYSCNEGYTLVGSSTITCTeNGGWSPPpPTCE 57
Sushi pfam00084
Sushi repeat (SCR repeat);
697-751 4.44e-07

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 47.49  E-value: 4.44e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 237757322  697 CDILPTIENAIIRGKnKKSYRTGEQVTVRCQSPYQMNGSDTVTCI-NGRWIGK-PVC 751
Cdd:pfam00084   1 CPPPPDIPNGKVSAT-KNEYNYGASVSYECDPGYRLVGSPTITCQeDGTWSPPfPEC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 697-751 8.00e-07

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 46.75  E-value: 8.00e-07
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 237757322   697 CDILPTIENAIIRGKNKkSYRTGEQVTVRCQSPYQMNGSDTVTCI-NGRWIGK-PVC 751
Cdd:smart00032   1 CPPPPDIENGTVTSSSG-TYSYGDTVTYSCDPGYTLIGSSTITCLeNGTWSPPpPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 332-386 1.33e-06

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 45.98  E-value: 1.33e-06
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 237757322   332 CAQPPEIPNGEINGAKRvEYSHGEVVGYDCKPRFLLKGPNKIQCV-DGMWT-TLPVC 386
Cdd:smart00032   1 CPPPPDIENGTVTSSSG-TYSYGDTVTYSCDPGYTLIGSSTITCLeNGTWSpPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
272-325 2.31e-06

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 45.57  E-value: 2.31e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 237757322  272 CSVPILDRKLVVSPRKEKYRVGDLLEFSCRSGHR-VGPDSVQC-YHFGWSPSFPTC 325
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRlVGSPTITCqEDGTWSPPFPEC 56
PHA02639 PHA02639
EEV host range protein; Provisional
 332-507 2.59e-06

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 50.05  E-value: 2.59e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 332 CAQPPEIPNGEINGAKRvEYSHGEVVGYDCKPRFLLKGPNKIQCV----DGMWTT-LPVCVEEErtCGDIPELEHGSVKF 406
Cdd:PHA02639  22 CDKPDDISNGFITELME-KYEIGKLIEYTCNTDYALIGDRFRTCIkdknNAIWSNkAPFCMLKE--CNDPPSIINGKIYN 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 407 SVPPYHHGDSVEFTCAE----TFTMIGLGSVFCLSGK-WTQLPKCVatdQLEKCR--VLKSTDIEAIkPKRKEFQHNSTM 479
Cdd:PHA02639  99 KREMYKVGDEIYYVCNEhkgvQYSLVGNEKITCIQDKsWKPDPPIC---KMINCRfpALQNGYINGI-PSNKKFYYKTRV 174

                        170       180       190
                 ....*....|....*....|....*....|...
gi 237757322 480 YYKCR---DKQEYEHSIC-INGKWNPE-PNCIR 507
Cdd:PHA02639 175 GFSCKsgfDLVGEKYSTCnINATWFPSiPTCVR 207
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 92-325 3.29e-06

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 50.08  E-value: 3.29e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322  92 CVFHYVENGQSAYWEKIYVQGQSLKVQCYNGYslQNGQDTMTCTENGWSPPPKCIriKTCSVSDI--EIENGFFSE--SF 167
Cdd:PHA02954  21 CTVPTMNNAKLTSTETSFNDKQKVTFTCDSGY--YSLDPNAVCETDKWKYENPCK--KMCTVSDYvsELYDKPLYEvnST 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 168 RTYALNRETSY-RCKQgyvtNTGETSgsitclqngWSPQPSCIKS-CERPVFENSVTKNNSTWFKLNDKLDYECLIGYEn 245
Cdd:PHA02954  97 ITLICKDETKYfRCEE----KNGNTS---------WNDTVTCPNAeCQPLQLEHGSCQPVKEKYSFGEHITINCDVGYE- 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 246 eyKHTKGSITCTYYGWSDTPSCYEiECSVPILDRKLVVSprkEKYRVGDLLEFSCRSGHRV-GPDSVQCYHFGWSPSFPT 324
Cdd:PHA02954 163 --VIGASYISCTANSWNVIPSCQQ-KCDIPSLSNGLISG---STFSIGGVIHLSCKSGFTLtGSPSSTCIDGKWNPVLPI 236


                 .
gi 237757322 325 C 325
Cdd:PHA02954 237 C 237
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 272-326 3.70e-06

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 44.76  E-value: 3.70e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 237757322 272 CSVPILDRKLVVSPRKEKYRVGDLLEFSCRSGHR-VGPDSVQCY-HFGWSPSFPTCK 326
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTlVGSSTITCTeNGGWSPPPPTCE 57
PHA02817 PHA02817
EEV Host range protein; Provisional
 634-751 4.22e-06

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 48.78  E-value: 4.22e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 634 CVGLPCGPPPSIPLGTVSLELESYQHGEEVTYHCSTG-----FGIDGPALIKCE-GGKWS-DPPKCIKTDCDiLPTIENA 706
Cdd:PHA02817  19 CDLNKCCYPPSIKNGYIYNKKTEYNIGSNVTFFCGNNtrgvrYTLVGEKNIICEkDGKWNkEFPVCKIIRCR-FPALQNG 97

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 237757322 707 IIRG--KNKKSYRTGEqVTVRCQSPYQMNGSDTVTC-INGRWIGK-PVC 751
Cdd:PHA02817  98 FVNGipDSKKFYYESE-VSFSCKPGFVLIGTKYSVCgINSSWIPKvPIC 145
Sushi pfam00084
Sushi repeat (SCR repeat);
758-812 5.26e-06

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 44.41  E-value: 5.26e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 237757322  758 CGPPPPIDNGDITSLSlPEYEPFSSVDYQCQKYYLLKGKKTITCR-NGKWS-EPPTC 812
Cdd:pfam00084   1 CPPPPDIPNGKVSATK-NEYNYGASVSYECDPGYRLVGSPTITCQeDGTWSpPFPEC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
639-692 5.97e-06

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 44.41  E-value: 5.97e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 237757322  639 CGPPPSIPLGTVSLELESYQHGEEVTYHCSTGFGIDGPALIKC-EGGKWSDP-PKC 692
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCqEDGTWSPPfPEC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 97-146 7.65e-06

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 43.99  E-value: 7.65e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 237757322  97 VENGQSAYWEKIYVQGQSLKVQCYNGYSLQnGQDTMTCTENG-WSP-PPKCI 146
Cdd:cd00033    7 PENGTVTGSKGSYSYGSTVTYSCNEGYTLV-GSSTITCTENGgWSPpPPTCE 57
PHA02831 PHA02831
EEV host range protein; Provisional
 92-243 1.51e-05

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 47.68  E-value: 1.51e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322  92 CVFHYVENGQS---AYWEKIYVQGQSLKVQCYNGYSlqngQDTMTCTENGWSPPPKCIRIKTCSvSDIEIENGFFSESFR 168
Cdd:PHA02831  20 CVFNKNDAKYSnvdSYENKVYEENENLEYKCNNNFD----KVFVTCNNGSWSTKNMCIGKRNCK-DPVTILNGYIKNKKD 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 169 TYALNRETSYRCK----QGYVTNTGETsgsITCLQNGWSPQ-PSC-IKSCERPVFENSVTKNNSTWFKLNDKLDYECLIG 242
Cdd:PHA02831  95 QYSFGDSVTYACKvnklEKYSIVGNET---VKCINKQWVPKyPVCkLIRCKYPALQNGFLNVFEKKFYYGDIVNFKCKKG 171


                 .
gi 237757322 243 Y 243
Cdd:PHA02831 172 F 172
PHA02831 PHA02831
EEV host range protein; Provisional
 471-635 1.86e-05

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 47.29  E-value: 1.86e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 471 KEFQHNSTMYYKCRDKQEYEHSICINGKWNPEPNCIRKISCPPPPQIPNTQVIETTVKYLDGEKLSVLCQDNYLTQ---- 546
Cdd:PHA02831  38 KVYEENENLEYKCNNNFDKVFVTCNNGSWSTKNMCIGKRNCKDPVTILNGYIKNKKDQYSFGDSVTYACKVNKLEKysiv 117

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 547 DPEEMMCKDGRW-QSLPHCieKIPCSQPPTIEHGSIKlprTSEKRrksiefssHEHGTTFSYVCDDGFRIPEENGVACYM 625
Cdd:PHA02831 118 GNETVKCINKQWvPKYPVC--KLIRCKYPALQNGFLN---VFEKK--------FYYGDIVNFKCKKGFILLGSSVSTCDI 184

                        170
                 ....*....|..
gi 237757322 626 GKWSTP--PRCV 635
Cdd:PHA02831 185 NSIWYPgiPKCV 196
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 97-145 1.92e-05

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 42.90  E-value: 1.92e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|.
gi 237757322    97 VENGQSAYWEKIYVQGQSLKVQCYNGYSLQnGQDTMTCTENG-WSPP-PKC 145
Cdd:smart00032   7 IENGTVTSSSGTYSYGDTVTYSCDPGYTLI-GSSTITCLENGtWSPPpPTC 56
PHA02817 PHA02817
EEV Host range protein; Provisional
 266-396 2.25e-05

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 46.47  E-value: 2.25e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 266 SCYEIECSVPILDRKLVVSPRKEKYRVGDLLEFSCRSGHR------VGPDSVQCYHFG-WSPSFPTCKgqVASCaQPPEI 338
Cdd:PHA02817  18 LCDLNKCCYPPSIKNGYIYNKKTEYNIGSNVTFFCGNNTRgvrytlVGEKNIICEKDGkWNKEFPVCK--IIRC-RFPAL 94

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 237757322 339 PNGEING-AKRVEYSHGEVVGYDCKPRFLLKG-PNKIQCVDGMW-TTLPVCVEEERTCGDI 396
Cdd:PHA02817  95 QNGFVNGiPDSKKFYYESEVSFSCKPGFVLIGtKYSVCGINSSWiPKVPICSRDNITYNKI 155
Sushi pfam00084
Sushi repeat (SCR repeat);
332-386 2.27e-05

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 42.49  E-value: 2.27e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 237757322  332 CAQPPEIPNGEINGaKRVEYSHGEVVGYDCKPRFLLKGPNKIQCV-DGMWT-TLPVC 386
Cdd:pfam00084   1 CPPPPDIPNGKVSA-TKNEYNYGASVSYECDPGYRLVGSPTITCQeDGTWSpPFPEC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 272-325 2.36e-05

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 42.51  E-value: 2.36e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 237757322   272 CSVPILDRKLVVSPRKEKYRVGDLLEFSCRSGHR-VGPDSVQCYHFG-WSPSFPTC 325
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTlIGSSTITCLENGtWSPPPPTC 56
PHA02831 PHA02831
EEV host range protein; Provisional
 714-854 2.99e-05

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 46.52  E-value: 2.99e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 714 KSYRTGEQVTVRCQSPYQmngSDTVTCINGRWIGKPVCKDSRgKCGPPPPIDNGDITSlSLPEYEPFSSVDYQCQ----K 789
Cdd:PHA02831  38 KVYEENENLEYKCNNNFD---KVFVTCNNGSWSTKNMCIGKR-NCKDPVTILNGYIKN-KKDQYSFGDSVTYACKvnklE 112

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 790 YYLLKGKKTITCRNGKW-SEPPTC-LHACIIP---ENIMEARKiilkwrhtKNIYshSGEDIEFECKYGY 854
Cdd:PHA02831 113 KYSIVGNETVKCINKQWvPKYPVCkLIRCKYPalqNGFLNVFE--------KKFY--YGDIVNFKCKKGF 172
Sushi pfam00084
Sushi repeat (SCR repeat);
393-446 4.47e-05

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 41.72  E-value: 4.47e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 237757322  393 CGDIPELEHGSVKFSVPPYHHGDSVEFTCAETFTMIGLGSVFCL-SGKWTQL-PKC 446
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQeDGTWSPPfPEC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 511-565 1.52e-04

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 40.52  E-value: 1.52e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 237757322 511 CPPPPQIPNTQVIETTVKYLDGEKLSVLCQDNYLTQDPEEMMC-KDGRW-QSLPHCI 565
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCtENGGWsPPPPTCE 57
PHA02817 PHA02817
EEV Host range protein; Provisional
 325-450 3.19e-04

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 43.01  E-value: 3.19e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 325 CKGQVASCAQPPEIPNGEINGaKRVEYSHGEVVGYDCKP-----RFLLKGPNKIQC-VDGMWTT-LPVCveeERTCGDIP 397
Cdd:PHA02817  17 SLCDLNKCCYPPSIKNGYIYN-KKTEYNIGSNVTFFCGNntrgvRYTLVGEKNIICeKDGKWNKeFPVC---KIIRCRFP 92

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 237757322 398 ELEHGSVKfSVP---PYHHGDSVEFTCAETFTMIGLGSVFC-LSGKW-TQLPKCVATD 450
Cdd:PHA02817  93 ALQNGFVN-GIPdskKFYYESEVSFSCKPGFVLIGTKYSVCgINSSWiPKVPICSRDN 149
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 157-209 1.06e-03

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 37.83  E-value: 1.06e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 237757322 157 EIENGFFSESFRTYALNRETSYRCKQGYVTNtgeTSGSITCLQNG-WSP-QPSCI 209
Cdd:cd00033    6 VPENGTVTGSKGSYSYGSTVTYSCNEGYTLV---GSSTITCTENGgWSPpPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 511-564 1.20e-03

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 37.89  E-value: 1.20e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 237757322   511 CPPPPQIPNTQVIETTVKYLDGEKLSVLCQDNYLTQDPEEMMC-KDGRW-QSLPHC 564
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITClENGTWsPPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 570-635 1.85e-03

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 37.44  E-value: 1.85e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 237757322 570 CSQPPTIEHGSIKLprtsekrrksiEFSSHEHGTTFSYVCDDGFRIPEENGVACYM-GKWS-TPPRCV 635
Cdd:cd00033    1 CPPPPVPENGTVTG-----------SKGSYSYGSTVTYSCNEGYTLVGSSTITCTEnGGWSpPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 157-208 2.63e-03

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 36.74  E-value: 2.63e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 237757322   157 EIENGFFSESFRTYALNRETSYRCKQGYVTNTGETsgsITCLQNG-WSP-QPSC 208
Cdd:smart00032   6 DIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSST---ITCLENGtWSPpPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 570-634 2.88e-03

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 36.74  E-value: 2.88e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 237757322   570 CSQPPTIEHGSIKLPRTSekrrksiefssHEHGTTFSYVCDDGFRIPEENGVACYM-GKWS-TPPRC 634
Cdd:smart00032   1 CPPPPDIENGTVTSSSGT-----------YSYGDTVTYSCDPGYTLIGSSTITCLEnGTWSpPPPTC 56
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 656-877 2.89e-03

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 40.84  E-value: 2.89e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 656 SYQHGEEVTYHCSTGFGIDGPALIkCEGGKWSDPPKCIKtdcdiLPTIENAIIRGKNKKSYRTGEQVTVRCQSPY----- 730
Cdd:PHA02954  37 SFNDKQKVTFTCDSGYYSLDPNAV-CETDKWKYENPCKK-----MCTVSDYVSELYDKPLYEVNSTITLICKDETkyfrc 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 731 -QMNGS----DTVTCINGRwigkpvCKDSRGKCGPPPPIDNgditSLSLPEYepfssVDYQCQKYYLLKGKKTITCRNGK 805
Cdd:PHA02954 111 eEKNGNtswnDTVTCPNAE------CQPLQLEHGSCQPVKE----KYSFGEH-----ITINCDVGYEVIGASYISCTANS 175

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 237757322 806 WSEPPTCLHACIIPEnimearkiILKWRHTKNIYSHSGEdIEFECKYGYhKARGSPpfRTKCISGTIN--YPIC 877
Cdd:PHA02954 176 WNVIPSCQQKCDIPS--------LSNGLISGSTFSIGGV-IHLSCKSGF-TLTGSP--SSTCIDGKWNpvLPIC 237
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 55-243 5.93e-03

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 39.68  E-value: 5.93e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322  55 KYSYKCDNGF--SPPSGIfwdylrCTVQGWEPEVPCVRKC-VFHYVengQSAYWEKIYVQGQSLKVQC-----YNGYSLQ 126
Cdd:PHA02954  43 KVTFTCDSGYysLDPNAV------CETDKWKYENPCKKMCtVSDYV---SELYDKPLYEVNSTITLICkdetkYFRCEEK 113

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 237757322 127 NGQ----DTMTCtengwsPPPKCiriktcsvSDIEIENGFFSESFRTYALNRETSYRCKQGYvtntgETSGS--ITCLQN 200
Cdd:PHA02954 114 NGNtswnDTVTC------PNAEC--------QPLQLEHGSCQPVKEKYSFGEHITINCDVGY-----EVIGAsyISCTAN 174

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 237757322 201 GWSPQPSCIKSCERPVFENSVTKNNStwFKLNDKLDYECLIGY 243
Cdd:PHA02954 175 SWNVIPSCQQKCDIPSLSNGLISGST--FSIGGVIHLSCKSGF 215
Sushi pfam00084
Sushi repeat (SCR repeat);
570-634 7.05e-03

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 35.55  E-value: 7.05e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 237757322  570 CSQPPTIEHGSIKLPRTSekrrksiefssHEHGTTFSYVCDDGFRIPEENGVAC-YMGKWS-TPPRC 634
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNE-----------YNYGASVSYECDPGYRLVGSPTITCqEDGTWSpPFPEC 56
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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