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Conserved domains on  [gi|239052134|ref|NP_001155096|]
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cyclin-dependent kinase inhibitor 1C isoform 1 [Mus musculus]

Protein Classification

cyclin-dependent kinase inhibitor( domain architecture ID 10491403)

cyclin-dependent kinase inhibitor is an important regulator of cell cycle progression

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CDI pfam02234
Cyclin-dependent kinase inhibitor; Cell cycle progression is negatively controlled by ...
 35-81 5.99e-12

Cyclin-dependent kinase inhibitor; Cell cycle progression is negatively controlled by cyclin-dependent kinases inhibitors (CDIs). CDIs are involved in cell cycle arrest at the G1 phase.


:

Pssm-ID: 460503  Cd Length: 46  Bit Score: 59.85  E-value: 5.99e-12
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 239052134   35 LFGPVDHEELGRELRMRLAELNAEDQNRWDFNFQQDVPLrgPGRLQW 81
Cdd:pfam02234   1 LFGPVDHEELEEFFQAALREQQERFSEKWNFDFVNDTPL--PGRYEW 45
PTZ00341 super family cl31759
Ring-infected erythrocyte surface antigen; Provisional
 197-281 2.02e-04

Ring-infected erythrocyte surface antigen; Provisional


The actual alignment was detected with superfamily member PTZ00341:

Pssm-ID: 173534 [Multi-domain]  Cd Length: 1136  Bit Score: 43.24  E-value: 2.02e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239052134  197 EEQVPEQVSEQGEESGAEPGDELGTEPVSEQgeEQGAEPVEEKDEEPEEEQGAEPVEEQGAEPVEEQNGEPVEEQDENQE 276
Cdd:PTZ00341 1000 EENIEENVEENVEENIEENVEEYDEENVEEV--EENVEEYDEENVEEIEENAEENVEENIEENIEEYDEENVEEIEENIE 1077


                  ....*
gi 239052134  277 QRGQE 281
Cdd:PTZ00341 1078 ENIEE 1082
 
Name Accession Description Interval E-value
CDI pfam02234
Cyclin-dependent kinase inhibitor; Cell cycle progression is negatively controlled by ...
 35-81 5.99e-12

Cyclin-dependent kinase inhibitor; Cell cycle progression is negatively controlled by cyclin-dependent kinases inhibitors (CDIs). CDIs are involved in cell cycle arrest at the G1 phase.


Pssm-ID: 460503  Cd Length: 46  Bit Score: 59.85  E-value: 5.99e-12
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 239052134   35 LFGPVDHEELGRELRMRLAELNAEDQNRWDFNFQQDVPLrgPGRLQW 81
Cdd:pfam02234   1 LFGPVDHEELEEFFQAALREQQERFSEKWNFDFVNDTPL--PGRYEW 45
PTZ00341 PTZ00341
Ring-infected erythrocyte surface antigen; Provisional
 197-281 2.02e-04

Ring-infected erythrocyte surface antigen; Provisional


Pssm-ID: 173534 [Multi-domain]  Cd Length: 1136  Bit Score: 43.24  E-value: 2.02e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239052134  197 EEQVPEQVSEQGEESGAEPGDELGTEPVSEQgeEQGAEPVEEKDEEPEEEQGAEPVEEQGAEPVEEQNGEPVEEQDENQE 276
Cdd:PTZ00341 1000 EENIEENVEENVEENIEENVEEYDEENVEEV--EENVEEYDEENVEEIEENAEENVEENIEENIEEYDEENVEEIEENIE 1077


                  ....*
gi 239052134  277 QRGQE 281
Cdd:PTZ00341 1078 ENIEE 1082
 
Name Accession Description Interval E-value
CDI pfam02234
Cyclin-dependent kinase inhibitor; Cell cycle progression is negatively controlled by ...
 35-81 5.99e-12

Cyclin-dependent kinase inhibitor; Cell cycle progression is negatively controlled by cyclin-dependent kinases inhibitors (CDIs). CDIs are involved in cell cycle arrest at the G1 phase.


Pssm-ID: 460503  Cd Length: 46  Bit Score: 59.85  E-value: 5.99e-12
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 239052134   35 LFGPVDHEELGRELRMRLAELNAEDQNRWDFNFQQDVPLrgPGRLQW 81
Cdd:pfam02234   1 LFGPVDHEELEEFFQAALREQQERFSEKWNFDFVNDTPL--PGRYEW 45
PTZ00341 PTZ00341
Ring-infected erythrocyte surface antigen; Provisional
 197-281 2.02e-04

Ring-infected erythrocyte surface antigen; Provisional


Pssm-ID: 173534 [Multi-domain]  Cd Length: 1136  Bit Score: 43.24  E-value: 2.02e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239052134  197 EEQVPEQVSEQGEESGAEPGDELGTEPVSEQgeEQGAEPVEEKDEEPEEEQGAEPVEEQGAEPVEEQNGEPVEEQDENQE 276
Cdd:PTZ00341 1000 EENIEENVEENVEENIEENVEEYDEENVEEV--EENVEEYDEENVEEIEENAEENVEENIEENIEEYDEENVEEIEENIE 1077


                  ....*
gi 239052134  277 QRGQE 281
Cdd:PTZ00341 1078 ENIEE 1082
PTZ00341 PTZ00341
Ring-infected erythrocyte surface antigen; Provisional
 197-285 5.70e-04

Ring-infected erythrocyte surface antigen; Provisional


Pssm-ID: 173534 [Multi-domain]  Cd Length: 1136  Bit Score: 42.08  E-value: 5.70e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239052134  197 EEQVPEQVSEQGEESgAEPGDELGTEPVSEQGEE---QGAEPVEEKDEEPEEEQGAEPVEEQGAEPVEEQNGEPVEEQDE 273
Cdd:PTZ00341 1046 EENAEENVEENIEEN-IEEYDEENVEEIEENIEEnieENVEENVEENVEEIEENVEENVEENAEENAEENAEENAEEYDD 1124

                          90
                  ....*....|..
gi 239052134  274 NQEQRGQELKDQ 285
Cdd:PTZ00341 1125 ENPEEHNEEYDE 1136
PTZ00341 PTZ00341
Ring-infected erythrocyte surface antigen; Provisional
 184-281 3.00e-03

Ring-infected erythrocyte surface antigen; Provisional


Pssm-ID: 173534 [Multi-domain]  Cd Length: 1136  Bit Score: 39.77  E-value: 3.00e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239052134  184 IPDANPDVATRDGEEQVPEQVSEQGEESGAEPGDELGTEPVSEQGEEQgaepVEEKDEEPEEEQGAEPVEEQGAEPVEEQ 263
Cdd:PTZ00341  947 IEEDAEENVEEDAEENVEENVEENVEENVEENVEENVEENVEENVEEN----VEENVEENIEENVEENVEENIEENVEEY 1022

                          90
                  ....*....|....*...
gi 239052134  264 NGEPVEEQDENQEQRGQE 281
Cdd:PTZ00341 1023 DEENVEEVEENVEEYDEE 1040
PTZ00341 PTZ00341
Ring-infected erythrocyte surface antigen; Provisional
 174-277 7.40e-03

Ring-infected erythrocyte surface antigen; Provisional


Pssm-ID: 173534 [Multi-domain]  Cd Length: 1136  Bit Score: 38.23  E-value: 7.40e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239052134  174 VATSDPTPDPIPDANPDVATRDGEEQVPEQVSEQGEESGAEPGDEL------GTEPVSEQGEEQGAEPVEEKDEEPEEEQ 247
Cdd:PTZ00341 1027 VEEVEENVEEYDEENVEEIEENAEENVEENIEENIEEYDEENVEEIeenieeNIEENVEENVEENVEEIEENVEENVEEN 1106

                          90       100       110
                  ....*....|....*....|....*....|
gi 239052134  248 GAEPVEEQGAEPVEEQNGEPVEEQDENQEQ 277
Cdd:PTZ00341 1107 AEENAEENAEENAEEYDDENPEEHNEEYDE 1136
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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