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Conserved domains on  [gi|258645137|ref|NP_001158272|]
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solute carrier family 38 member 10 isoform 4 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
SLC5-6-like_sbd super family cl00456
Solute carrier families 5 and 6-like; solute binding domain; This superfamily includes the ...
6-381 1.12e-52

Solute carrier families 5 and 6-like; solute binding domain; This superfamily includes the solute-binding domain of SLC5 proteins (also called the sodium/glucose cotransporters or solute sodium symporters), SLC6 proteins (also called the sodium- and chloride-dependent neurotransmitter transporters or Na+/Cl--dependent transporters), and nucleobase-cation-symport-1 (NCS1) transporters. SLC5s co-transport Na+ with sugars, amino acids, inorganic ions or vitamins. SLC6s include Na+/Cl--dependent plasma membrane transporters for the monoamine neurotransmitters serotonin, dopamine, and norepinephrine, and the amino acid neurotransmitters GABA and glycine. NCS1s are essential components of salvage pathways for nucleobases and related metabolites; their known substrates include allantoin, uracil, thiamine, and nicotinamide riboside. Members of this superfamily are important in human physiology and disease. They contain a functional core of 10 transmembrane helices (TMs): an inverted structural repeat, TMs1-5 and TMs6-10; TMs numbered to conform to the SLC6 Aquifex aeolicus LeuT.


The actual alignment was detected with superfamily member pfam01490:

Pssm-ID: 444915  Cd Length: 410  Bit Score: 190.59  E-value: 1.12e-52
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137     6 TSKWGLITNVVNSIVGVSVLTMPFCFKQCGIVLGALLLVFCSWMTHQSCMFLVKSA-----SLSKRRTYAGLAFHAYGKA 80
Cdd:pfam01490    3 ISAWQAVFNLINAIIGAGVLSLPYAFKQLGWIPGLILLLIVGLISLYTAHLLVRCSkevpvTGKRNKSYGDLGYRLLGPK 82
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137    81 GKMLVETSMIGLMLGSCITFYVVIGDLGSNFFAPLLGlqvTRTVRVFLLFAVSLFIVLPLSLQRNMMA-SIQS-FSAMAL 158
Cdd:pfam01490   83 GRLLILFAILLNLFGVCISYLIFAGDNLPAIFDSFFD---TCPISLVYFIIIFGLIFIPLSFIPNLSAlSILSlLAAVSS 159
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137   159 LFYTVFMFVIVLSSLKHGLFSGQWLRQVSYIRWEGVFRCVPIFGMSFACQSQVLPTYDSLDEPSV-KTMSSIFASSLNVV 237
Cdd:pfam01490  160 LYYIVILVLSVAEGIVLTAQGVGHLGSKTNIKLAGTFLAIGIIVFAFEGHAVLLPIQNEMKNPSKfKAMTKILLTAIIIA 239
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137   238 TAFYVMVGFFGYVSFTDATTGNVLIHFP-SNPVTEMIRVGFVMSVAVGFPMMILPCRQALNTLLFEQQqkdgTFAAGGYM 316
Cdd:pfam01490  240 TVLYILIGLVGYLAFGDNVKGNILLNLPkSAWLIDIANLLLVLHVILSFPLQLFPIRQIVENLLFRKE----APFGASGK 315
                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 258645137   317 PP----LRFKVLTLSVVFGTMVGGVMIPNVETILGFTGATMGSLICFICPALIYKKAHKNAPSAQVVLW 381
Cdd:pfam01490  316 NNpkskLLRVVIRSGLVVITYLIAISVPFFGDLLSLVGATSCAPLSFILPPLFHLKLKKTKKKSQEKLW 384
PTZ00121 super family cl31754
MAEBL; Provisional
407-761 1.10e-08

MAEBL; Provisional


The actual alignment was detected with superfamily member PTZ00121:

Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 59.77  E-value: 1.10e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137  407 QEARSGHRGDAEGAMKVEAARLSVQdpvVVVAEDSQ--EKLKPAEDKEVLEQAQIKGPVDVPGGEAPKEKQEA------- 477
Cdd:PTZ00121 1258 EEARMAHFARRQAAIKAEEARKADE---LKKAEEKKkaDEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAkkkadaa 1334
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137  478 ---AQLDRPGQGIAVPMGEAHRHEPPIPHDKVVVDEGQDQEgpeEKKPPPRLPDEGDPAGRGQGAPPLPESEKEK----- 549
Cdd:PTZ00121 1335 kkkAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEE---AKKKADAAKKKAEEKKKADEAKKKAEEDKKKadelk 1411
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137  550 ---QEPERGGEGKRPGQVLAVGEtEHPQKVPEANGQPPVQPRKEDSRPGNRDPQPAAQARDSVELKALA-----ADDGR- 620
Cdd:PTZ00121 1412 kaaAAKKKADEAKKKAEEKKKAD-EAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAeeakkADEAKk 1490
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137  621 --EPAQKAGGALWKPVESAAESDAGGKAGLPVQRPEAAEQREKKEAEQQGGDQAGSKLEEAGRAEMLDHAVLLQVIQEQQ 698
Cdd:PTZ00121 1491 kaEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAK 1570
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137  699 VQQKR---------LLDQQEK-----LLAVIEEQHKEIRQQRQEGEEDKPKPDV-----QPEPGVAVLRGQEEEAEHAGE 759
Cdd:PTZ00121 1571 KAEEDknmalrkaeEAKKAEEarieeVMKLYEEEKKMKAEEAKKAEEAKIKAEElkkaeEEKKKVEQLKKKEAEEKKKAE 1650

                  ..
gi 258645137  760 TL 761
Cdd:PTZ00121 1651 EL 1652
PTZ00449 super family cl33186
104 kDa microneme/rhoptry antigen; Provisional
702-961 6.83e-05

104 kDa microneme/rhoptry antigen; Provisional


The actual alignment was detected with superfamily member PTZ00449:

Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 46.99  E-value: 6.83e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137  702 KRLLDQQEKLLAVIEEQHKEIRQQRQEGEEDKPKPDVQPEpgvavlrGQEEEAEHAGETLGDDPSQ----PLQPVLGAPR 777
Cdd:PTZ00449  486 KKLIKKSKKKLAPIEEEDSDKHDEPPEGPEASGLPPKAPG-------DKEGEEGEHEDSKESDEPKeggkPGETKEGEVG 558
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137  778 GRPAPSQdmgQHLPGEVKVLPGRdladlPAGGSETEPQGAPIDLR--EDPKAAIKAAGAGKELVPGDLEAVHKAAPPEVP 855
Cdd:PTZ00449  559 KKPGPAK---EHKPSKIPTLSKK-----PEFPKDPKHPKDPEEPKkpKRPRSAQRPTRPKSPKLPELLDIPKSPKRPESP 630
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137  856 KSPEKQVAKavagQRqdvfgEGSEERKETGKEAMAPGA-DTQKEAVQPLVGAEAKDTKSRQSGPTKAPVQTQA------- 927
Cdd:PTZ00449  631 KSPKRPPPP----QR-----PSSPERPEGPKIIKSPKPpKSPKPPFDPKFKEKFYDDYLDAAAKSKETKTTVVldesfes 701
                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 258645137  928 ---KFHPEPQAIFDTGQGSHPEVRSEAPRAVHIPPEE 961
Cdd:PTZ00449  702 ilkETLPETPGTPFTTPRPLPPKLPRDEEFPFEPIGD 738
 
Name Accession Description Interval E-value
Aa_trans pfam01490
Transmembrane amino acid transporter protein; This transmembrane region is found in many amino ...
6-381 1.12e-52

Transmembrane amino acid transporter protein; This transmembrane region is found in many amino acid transporters including UNC-47 and MTR. UNC-47 encodes a vesicular amino butyric acid (GABA) transporter, (VGAT). UNC-47 is predicted to have 10 transmembrane domains. MTR is a N system amino acid transporter system protein involved in methyltryptophan resistance. Other members of this family include proline transporters and amino acid permeases.


Pssm-ID: 279788  Cd Length: 410  Bit Score: 190.59  E-value: 1.12e-52
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137     6 TSKWGLITNVVNSIVGVSVLTMPFCFKQCGIVLGALLLVFCSWMTHQSCMFLVKSA-----SLSKRRTYAGLAFHAYGKA 80
Cdd:pfam01490    3 ISAWQAVFNLINAIIGAGVLSLPYAFKQLGWIPGLILLLIVGLISLYTAHLLVRCSkevpvTGKRNKSYGDLGYRLLGPK 82
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137    81 GKMLVETSMIGLMLGSCITFYVVIGDLGSNFFAPLLGlqvTRTVRVFLLFAVSLFIVLPLSLQRNMMA-SIQS-FSAMAL 158
Cdd:pfam01490   83 GRLLILFAILLNLFGVCISYLIFAGDNLPAIFDSFFD---TCPISLVYFIIIFGLIFIPLSFIPNLSAlSILSlLAAVSS 159
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137   159 LFYTVFMFVIVLSSLKHGLFSGQWLRQVSYIRWEGVFRCVPIFGMSFACQSQVLPTYDSLDEPSV-KTMSSIFASSLNVV 237
Cdd:pfam01490  160 LYYIVILVLSVAEGIVLTAQGVGHLGSKTNIKLAGTFLAIGIIVFAFEGHAVLLPIQNEMKNPSKfKAMTKILLTAIIIA 239
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137   238 TAFYVMVGFFGYVSFTDATTGNVLIHFP-SNPVTEMIRVGFVMSVAVGFPMMILPCRQALNTLLFEQQqkdgTFAAGGYM 316
Cdd:pfam01490  240 TVLYILIGLVGYLAFGDNVKGNILLNLPkSAWLIDIANLLLVLHVILSFPLQLFPIRQIVENLLFRKE----APFGASGK 315
                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 258645137   317 PP----LRFKVLTLSVVFGTMVGGVMIPNVETILGFTGATMGSLICFICPALIYKKAHKNAPSAQVVLW 381
Cdd:pfam01490  316 NNpkskLLRVVIRSGLVVITYLIAISVPFFGDLLSLVGATSCAPLSFILPPLFHLKLKKTKKKSQEKLW 384
PTZ00206 PTZ00206
amino acid transporter; Provisional
14-366 1.73e-25

amino acid transporter; Provisional


Pssm-ID: 240313  Cd Length: 467  Bit Score: 111.50  E-value: 1.73e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137   14 NVVNSIVGVSVLTMPFCFKQCGIVLGALLLVFCSWMTHQSCMFLVKSASLSKRRTYAGLAFHAYGKAGKMLVETSMIGLM 93
Cdd:PTZ00206   68 NIASSTVGAGIVGLPSAANSSGLVMAMIYLIIITAMTIFSIYALGVAADKTNIRTYEGVARVLLGPWGSYYVAATRAFHG 147
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137   94 LGSCITFYVVIGDLGSnffAPLLGLQV-----TRTVRVFLLFAVSLFIVLPLSLQRNMmASIQSFSAMALLFYTVFMFVI 168
Cdd:PTZ00206  148 FSACVAYVISVGDILS---ATLKGTNApdflkQKSGNRLLTSLMWLCFMLPLVIPRHI-DSLRYVSTIAVSFMVYLVIVI 223
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137  169 VLSSLKHGLfsGQWLRQVSY--------IRWEGVFRCVP---IFGMSFACQSQVLPTYDSLDEPSVKTMSSIFASSLNVV 237
Cdd:PTZ00206  224 VVHSCMNGL--PENIKNVSVgkddnaeiILFNSGNRAIEglgVFIFAYVFQITAYEVYMDMTNRSVGKFVLASTIAMGMC 301
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137  238 TAFYVMVGFFGYVSFTDATTGNVLIHFpsNPVTE-MIRVGFV---MSVAVGFPMMILPCRQALNTLLFEQQQKDGTFAAG 313
Cdd:PTZ00206  302 FTMYVLTAFFGYMDFGRNVTGSVLLMY--DPVNEpAIMVGFVgvlVKLFVSYALLGMACRNALYDVIGWDARKVAFWKHC 379
                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|...
gi 258645137  314 gympplrFKVLTLSVVFgtMVGGVMIPNVETILGFTGATMGSLICFICPALIY 366
Cdd:PTZ00206  380 -------IAVVTLSVVM--LLCGLFIPKINTVLGFAGSISGGLLGFILPALLF 423
PTZ00121 PTZ00121
MAEBL; Provisional
407-761 1.10e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 59.77  E-value: 1.10e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137  407 QEARSGHRGDAEGAMKVEAARLSVQdpvVVVAEDSQ--EKLKPAEDKEVLEQAQIKGPVDVPGGEAPKEKQEA------- 477
Cdd:PTZ00121 1258 EEARMAHFARRQAAIKAEEARKADE---LKKAEEKKkaDEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAkkkadaa 1334
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137  478 ---AQLDRPGQGIAVPMGEAHRHEPPIPHDKVVVDEGQDQEgpeEKKPPPRLPDEGDPAGRGQGAPPLPESEKEK----- 549
Cdd:PTZ00121 1335 kkkAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEE---AKKKADAAKKKAEEKKKADEAKKKAEEDKKKadelk 1411
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137  550 ---QEPERGGEGKRPGQVLAVGEtEHPQKVPEANGQPPVQPRKEDSRPGNRDPQPAAQARDSVELKALA-----ADDGR- 620
Cdd:PTZ00121 1412 kaaAAKKKADEAKKKAEEKKKAD-EAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAeeakkADEAKk 1490
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137  621 --EPAQKAGGALWKPVESAAESDAGGKAGLPVQRPEAAEQREKKEAEQQGGDQAGSKLEEAGRAEMLDHAVLLQVIQEQQ 698
Cdd:PTZ00121 1491 kaEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAK 1570
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137  699 VQQKR---------LLDQQEK-----LLAVIEEQHKEIRQQRQEGEEDKPKPDV-----QPEPGVAVLRGQEEEAEHAGE 759
Cdd:PTZ00121 1571 KAEEDknmalrkaeEAKKAEEarieeVMKLYEEEKKMKAEEAKKAEEAKIKAEElkkaeEEKKKVEQLKKKEAEEKKKAE 1650

                  ..
gi 258645137  760 TL 761
Cdd:PTZ00121 1651 EL 1652
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
702-961 6.83e-05

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 46.99  E-value: 6.83e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137  702 KRLLDQQEKLLAVIEEQHKEIRQQRQEGEEDKPKPDVQPEpgvavlrGQEEEAEHAGETLGDDPSQ----PLQPVLGAPR 777
Cdd:PTZ00449  486 KKLIKKSKKKLAPIEEEDSDKHDEPPEGPEASGLPPKAPG-------DKEGEEGEHEDSKESDEPKeggkPGETKEGEVG 558
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137  778 GRPAPSQdmgQHLPGEVKVLPGRdladlPAGGSETEPQGAPIDLR--EDPKAAIKAAGAGKELVPGDLEAVHKAAPPEVP 855
Cdd:PTZ00449  559 KKPGPAK---EHKPSKIPTLSKK-----PEFPKDPKHPKDPEEPKkpKRPRSAQRPTRPKSPKLPELLDIPKSPKRPESP 630
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137  856 KSPEKQVAKavagQRqdvfgEGSEERKETGKEAMAPGA-DTQKEAVQPLVGAEAKDTKSRQSGPTKAPVQTQA------- 927
Cdd:PTZ00449  631 KSPKRPPPP----QR-----PSSPERPEGPKIIKSPKPpKSPKPPFDPKFKEKFYDDYLDAAAKSKETKTTVVldesfes 701
                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 258645137  928 ---KFHPEPQAIFDTGQGSHPEVRSEAPRAVHIPPEE 961
Cdd:PTZ00449  702 ilkETLPETPGTPFTTPRPLPPKLPRDEEFPFEPIGD 738
PspC_subgroup_2 NF033839
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...
433-601 9.93e-05

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.


Pssm-ID: 468202 [Multi-domain]  Cd Length: 557  Bit Score: 46.30  E-value: 9.93e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137  433 PVVVVAEDSQEKLKPAEDK---EVLEQAQIKGPVDVPGGEAPKEKQEAaQLDRPGQGIAvPMGEAHRHE------PPIPH 503
Cdd:NF033839  309 EVKPEPETPKPEVKPQLEKpkpEVKPQPEKPKPEVKPQLETPKPEVKP-QPEKPKPEVK-PQPEKPKPEvkpqpeTPKPE 386
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137  504 DKVVVDEGQDQEGPEEKKPPPRL---PDEGDPAGRGQGAPPLPE----SEKEKQEPERGGEGKRPgQVLAVGETEHPQKV 576
Cdd:NF033839  387 VKPQPEKPKPEVKPQPEKPKPEVkpqPEKPKPEVKPQPEKPKPEvkpqPEKPKPEVKPQPEKPKP-EVKPQPETPKPEVK 465
                         170       180
                  ....*....|....*....|....*.
gi 258645137  577 PEANG-QPPVQPRKEDSRPGNRDPQP 601
Cdd:NF033839  466 PQPEKpKPEVKPQPEKPKPDNSKPQA 491
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
505-769 4.27e-04

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 44.60  E-value: 4.27e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137   505 KVVVDEGQD--QEGPEEKKPPPRLPDEGDPAGRGQGAPPLPESEKEKQEPERGGEGKRPGQVLAVGETEHPQKVPEANGQ 582
Cdd:TIGR00927  632 KGDVAEAEHtgERTGEEGERPTEAEGENGEESGGEAEQEGETETKGENESEGEIPAERKGEQEGEGEIEAKEADHKGETE 711
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137   583 PPVQPRKEDSRPGNRDPQPAAQARDSVELKalaADDGREPAQKAggalwKPVESAAESDAGGKAGLPVQRPEAAEQREKK 662
Cdd:TIGR00927  712 AEEVEHEGETEAEGTEDEGEIETGEEGEEV---EDEGEGEAEGK-----HEVETEGDRKETEHEGETEAEGKEDEDEGEI 783
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137   663 EAEQQG---GDQAGSKLEEAGRAEMLDHAVLLQVIQEQQVQQKRLLDQQEKlLAVIEEQHKEIRQQRQ--EGEEDKPKPD 737
Cdd:TIGR00927  784 QAGEDGemkGDEGAEGKVEHEGETEAGEKDEHEGQSETQADDTEVKDETGE-QELNAENQGEAKQDEKgvDGGGGSDGGD 862
                          250       260       270
                   ....*....|....*....|....*....|..
gi 258645137   738 VQPEPGVAVLRGQEEEAEHAGETLGDDPSQPL 769
Cdd:TIGR00927  863 SEEEEEEEEEEEEEEEEEEEEEEEEEENEEPL 894
 
Name Accession Description Interval E-value
Aa_trans pfam01490
Transmembrane amino acid transporter protein; This transmembrane region is found in many amino ...
6-381 1.12e-52

Transmembrane amino acid transporter protein; This transmembrane region is found in many amino acid transporters including UNC-47 and MTR. UNC-47 encodes a vesicular amino butyric acid (GABA) transporter, (VGAT). UNC-47 is predicted to have 10 transmembrane domains. MTR is a N system amino acid transporter system protein involved in methyltryptophan resistance. Other members of this family include proline transporters and amino acid permeases.


Pssm-ID: 279788  Cd Length: 410  Bit Score: 190.59  E-value: 1.12e-52
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137     6 TSKWGLITNVVNSIVGVSVLTMPFCFKQCGIVLGALLLVFCSWMTHQSCMFLVKSA-----SLSKRRTYAGLAFHAYGKA 80
Cdd:pfam01490    3 ISAWQAVFNLINAIIGAGVLSLPYAFKQLGWIPGLILLLIVGLISLYTAHLLVRCSkevpvTGKRNKSYGDLGYRLLGPK 82
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137    81 GKMLVETSMIGLMLGSCITFYVVIGDLGSNFFAPLLGlqvTRTVRVFLLFAVSLFIVLPLSLQRNMMA-SIQS-FSAMAL 158
Cdd:pfam01490   83 GRLLILFAILLNLFGVCISYLIFAGDNLPAIFDSFFD---TCPISLVYFIIIFGLIFIPLSFIPNLSAlSILSlLAAVSS 159
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137   159 LFYTVFMFVIVLSSLKHGLFSGQWLRQVSYIRWEGVFRCVPIFGMSFACQSQVLPTYDSLDEPSV-KTMSSIFASSLNVV 237
Cdd:pfam01490  160 LYYIVILVLSVAEGIVLTAQGVGHLGSKTNIKLAGTFLAIGIIVFAFEGHAVLLPIQNEMKNPSKfKAMTKILLTAIIIA 239
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137   238 TAFYVMVGFFGYVSFTDATTGNVLIHFP-SNPVTEMIRVGFVMSVAVGFPMMILPCRQALNTLLFEQQqkdgTFAAGGYM 316
Cdd:pfam01490  240 TVLYILIGLVGYLAFGDNVKGNILLNLPkSAWLIDIANLLLVLHVILSFPLQLFPIRQIVENLLFRKE----APFGASGK 315
                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 258645137   317 PP----LRFKVLTLSVVFGTMVGGVMIPNVETILGFTGATMGSLICFICPALIYKKAHKNAPSAQVVLW 381
Cdd:pfam01490  316 NNpkskLLRVVIRSGLVVITYLIAISVPFFGDLLSLVGATSCAPLSFILPPLFHLKLKKTKKKSQEKLW 384
PTZ00206 PTZ00206
amino acid transporter; Provisional
14-366 1.73e-25

amino acid transporter; Provisional


Pssm-ID: 240313  Cd Length: 467  Bit Score: 111.50  E-value: 1.73e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137   14 NVVNSIVGVSVLTMPFCFKQCGIVLGALLLVFCSWMTHQSCMFLVKSASLSKRRTYAGLAFHAYGKAGKMLVETSMIGLM 93
Cdd:PTZ00206   68 NIASSTVGAGIVGLPSAANSSGLVMAMIYLIIITAMTIFSIYALGVAADKTNIRTYEGVARVLLGPWGSYYVAATRAFHG 147
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137   94 LGSCITFYVVIGDLGSnffAPLLGLQV-----TRTVRVFLLFAVSLFIVLPLSLQRNMmASIQSFSAMALLFYTVFMFVI 168
Cdd:PTZ00206  148 FSACVAYVISVGDILS---ATLKGTNApdflkQKSGNRLLTSLMWLCFMLPLVIPRHI-DSLRYVSTIAVSFMVYLVIVI 223
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137  169 VLSSLKHGLfsGQWLRQVSY--------IRWEGVFRCVP---IFGMSFACQSQVLPTYDSLDEPSVKTMSSIFASSLNVV 237
Cdd:PTZ00206  224 VVHSCMNGL--PENIKNVSVgkddnaeiILFNSGNRAIEglgVFIFAYVFQITAYEVYMDMTNRSVGKFVLASTIAMGMC 301
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137  238 TAFYVMVGFFGYVSFTDATTGNVLIHFpsNPVTE-MIRVGFV---MSVAVGFPMMILPCRQALNTLLFEQQQKDGTFAAG 313
Cdd:PTZ00206  302 FTMYVLTAFFGYMDFGRNVTGSVLLMY--DPVNEpAIMVGFVgvlVKLFVSYALLGMACRNALYDVIGWDARKVAFWKHC 379
                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|...
gi 258645137  314 gympplrFKVLTLSVVFgtMVGGVMIPNVETILGFTGATMGSLICFICPALIY 366
Cdd:PTZ00206  380 -------IAVVTLSVVM--LLCGLFIPKINTVLGFAGSISGGLLGFILPALLF 423
PTZ00121 PTZ00121
MAEBL; Provisional
407-761 1.10e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 59.77  E-value: 1.10e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137  407 QEARSGHRGDAEGAMKVEAARLSVQdpvVVVAEDSQ--EKLKPAEDKEVLEQAQIKGPVDVPGGEAPKEKQEA------- 477
Cdd:PTZ00121 1258 EEARMAHFARRQAAIKAEEARKADE---LKKAEEKKkaDEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAkkkadaa 1334
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137  478 ---AQLDRPGQGIAVPMGEAHRHEPPIPHDKVVVDEGQDQEgpeEKKPPPRLPDEGDPAGRGQGAPPLPESEKEK----- 549
Cdd:PTZ00121 1335 kkkAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEE---AKKKADAAKKKAEEKKKADEAKKKAEEDKKKadelk 1411
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137  550 ---QEPERGGEGKRPGQVLAVGEtEHPQKVPEANGQPPVQPRKEDSRPGNRDPQPAAQARDSVELKALA-----ADDGR- 620
Cdd:PTZ00121 1412 kaaAAKKKADEAKKKAEEKKKAD-EAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAeeakkADEAKk 1490
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137  621 --EPAQKAGGALWKPVESAAESDAGGKAGLPVQRPEAAEQREKKEAEQQGGDQAGSKLEEAGRAEMLDHAVLLQVIQEQQ 698
Cdd:PTZ00121 1491 kaEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAK 1570
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137  699 VQQKR---------LLDQQEK-----LLAVIEEQHKEIRQQRQEGEEDKPKPDV-----QPEPGVAVLRGQEEEAEHAGE 759
Cdd:PTZ00121 1571 KAEEDknmalrkaeEAKKAEEarieeVMKLYEEEKKMKAEEAKKAEEAKIKAEElkkaeEEKKKVEQLKKKEAEEKKKAE 1650

                  ..
gi 258645137  760 TL 761
Cdd:PTZ00121 1651 EL 1652
PTZ00121 PTZ00121
MAEBL; Provisional
407-759 5.42e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 53.99  E-value: 5.42e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137  407 QEARSghrgdAEGAMKVEAARLSVQDPVVVVA---EDSQ--EKLKPAEDKEVLEQA----QIKGPVDVPGGEAPKEKQEA 477
Cdd:PTZ00121 1131 EEARK-----AEDARKAEEARKAEDAKRVEIArkaEDARkaEEARKAEDAKKAEAArkaeEVRKAEELRKAEDARKAEAA 1205
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137  478 AQLDRPGQGIAVPMGE-AHRHEPPIPHDKVVVDEGQDQEGPEEKKPPP-RLPDEGDPAGRGQGAPPLPESEKEKQEPERG 555
Cdd:PTZ00121 1206 RKAEEERKAEEARKAEdAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEiRKFEEARMAHFARRQAAIKAEEARKADELKK 1285
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137  556 GEGKRPGQVLAvgETEHPQKVPEANgqppvqprkedsrpgnrdpQPAAQARDSVELKALAaddgrEPAQKAGGALWKPVE 635
Cdd:PTZ00121 1286 AEEKKKADEAK--KAEEKKKADEAK-------------------KKAEEAKKADEAKKKA-----EEAKKKADAAKKKAE 1339
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137  636 SAAESDAGGKAGLPVQRPEAAEQREKKEAEQQGGDQAGSKLEEA-GRAEMLDHAvllQVIQEQQVQQKRLLDQQEKllav 714
Cdd:PTZ00121 1340 EAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAkKKAEEKKKA---DEAKKKAEEDKKKADELKK---- 1412
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*....
gi 258645137  715 IEEQHKEIRQQRQEGEE----DKPKPDVQPEPGVAVLRGQEEEAEHAGE 759
Cdd:PTZ00121 1413 AAAAKKKADEAKKKAEEkkkaDEAKKKAEEAKKADEAKKKAEEAKKAEE 1461
PTZ00121 PTZ00121
MAEBL; Provisional
417-761 3.20e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 48.21  E-value: 3.20e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137  417 AEGAMKVEAARLSVQDPvvvvAEDSQEKLKPAEDKEVLEQAQIKGPVDVPGGEAPKEKQEAAQLDRPGQGIAvpmgEAHR 496
Cdd:PTZ00121 1387 AEEKKKADEAKKKAEED----KKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAE----EAKK 1458
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137  497 HE--PPIPHDKVVVDEGQDQegPEEKKPPPRLPDEGDPAGRGQGAPPLPESEKEKQEPERGGEGKRPGQVLAvgETEHPQ 574
Cdd:PTZ00121 1459 AEeaKKKAEEAKKADEAKKK--AEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAK--KAEEAK 1534
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137  575 KVPEANGQPPVQP----RKEDSRPGNRDPQPAAQARDSVELKALAADDGrEPAQKAGGALWKPVESAAESDAGGKAGLPV 650
Cdd:PTZ00121 1535 KADEAKKAEEKKKadelKKAEELKKAEEKKKAEEAKKAEEDKNMALRKA-EEAKKAEEARIEEVMKLYEEEKKMKAEEAK 1613
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137  651 QRPEA---AEQREKKEAEQQGGDQAGSKL-EEAGRAEMLDHAVLLQVIQEQQVQQKRLLDQQ--EKLLAVIEEQHKEIRQ 724
Cdd:PTZ00121 1614 KAEEAkikAEELKKAEEEKKKVEQLKKKEaEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKkaEEAKKAEEDEKKAAEA 1693
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|..
gi 258645137  725 QRQEGEEDKPKPDVQPEPGVAV-----LRGQEEEAEHAGETL 761
Cdd:PTZ00121 1694 LKKEAEEAKKAEELKKKEAEEKkkaeeLKKAEEENKIKAEEA 1735
PHA03169 PHA03169
hypothetical protein; Provisional
510-672 5.07e-05

hypothetical protein; Provisional


Pssm-ID: 223003 [Multi-domain]  Cd Length: 413  Bit Score: 46.89  E-value: 5.07e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137  510 EGQDQEGPEEKKPPPRLPDEGDPAGRGQGAPPLPESEKEKQEPERGGEGKRPgqvlavGETEhpqkvpEANGQPPVQPRK 589
Cdd:PHA03169   98 ESVGSPTPSPSGSAEELASGLSPENTSGSSPESPASHSPPPSPPSHPGPHEP------APPE------SHNPSPNQQPSS 165
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137  590 EDSRPGNRDPQPAAQArdsvelKALAADDGREPAQKAGGALWKPVESAAESDAGGKAGLPVQRPEAAEQREKKEAEQQGG 669
Cdd:PHA03169  166 FLQPSHEDSPEEPEPP------TSEPEPDSPGPPQSETPTSSPPPQSPPDEPGEPQSPTPQQAPSPNTQQAVEHEDEPTE 239

                  ...
gi 258645137  670 DQA 672
Cdd:PHA03169  240 PER 242
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
702-961 6.83e-05

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 46.99  E-value: 6.83e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137  702 KRLLDQQEKLLAVIEEQHKEIRQQRQEGEEDKPKPDVQPEpgvavlrGQEEEAEHAGETLGDDPSQ----PLQPVLGAPR 777
Cdd:PTZ00449  486 KKLIKKSKKKLAPIEEEDSDKHDEPPEGPEASGLPPKAPG-------DKEGEEGEHEDSKESDEPKeggkPGETKEGEVG 558
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137  778 GRPAPSQdmgQHLPGEVKVLPGRdladlPAGGSETEPQGAPIDLR--EDPKAAIKAAGAGKELVPGDLEAVHKAAPPEVP 855
Cdd:PTZ00449  559 KKPGPAK---EHKPSKIPTLSKK-----PEFPKDPKHPKDPEEPKkpKRPRSAQRPTRPKSPKLPELLDIPKSPKRPESP 630
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137  856 KSPEKQVAKavagQRqdvfgEGSEERKETGKEAMAPGA-DTQKEAVQPLVGAEAKDTKSRQSGPTKAPVQTQA------- 927
Cdd:PTZ00449  631 KSPKRPPPP----QR-----PSSPERPEGPKIIKSPKPpKSPKPPFDPKFKEKFYDDYLDAAAKSKETKTTVVldesfes 701
                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 258645137  928 ---KFHPEPQAIFDTGQGSHPEVRSEAPRAVHIPPEE 961
Cdd:PTZ00449  702 ilkETLPETPGTPFTTPRPLPPKLPRDEEFPFEPIGD 738
PspC_subgroup_2 NF033839
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...
433-601 9.93e-05

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.


Pssm-ID: 468202 [Multi-domain]  Cd Length: 557  Bit Score: 46.30  E-value: 9.93e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137  433 PVVVVAEDSQEKLKPAEDK---EVLEQAQIKGPVDVPGGEAPKEKQEAaQLDRPGQGIAvPMGEAHRHE------PPIPH 503
Cdd:NF033839  309 EVKPEPETPKPEVKPQLEKpkpEVKPQPEKPKPEVKPQLETPKPEVKP-QPEKPKPEVK-PQPEKPKPEvkpqpeTPKPE 386
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137  504 DKVVVDEGQDQEGPEEKKPPPRL---PDEGDPAGRGQGAPPLPE----SEKEKQEPERGGEGKRPgQVLAVGETEHPQKV 576
Cdd:NF033839  387 VKPQPEKPKPEVKPQPEKPKPEVkpqPEKPKPEVKPQPEKPKPEvkpqPEKPKPEVKPQPEKPKP-EVKPQPETPKPEVK 465
                         170       180
                  ....*....|....*....|....*.
gi 258645137  577 PEANG-QPPVQPRKEDSRPGNRDPQP 601
Cdd:NF033839  466 PQPEKpKPEVKPQPEKPKPDNSKPQA 491
PTZ00121 PTZ00121
MAEBL; Provisional
417-755 1.15e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 46.67  E-value: 1.15e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137  417 AEGAMKVEAARLSVQDpvvvvAEDSQEKLKPAEDKEVLEQAQIKGPVDVPGGEAPKEKQEA---AQLDRPGQGIAVPMGE 493
Cdd:PTZ00121 1440 AEEAKKADEAKKKAEE-----AKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAkkkADEAKKAAEAKKKADE 1514
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137  494 AHRHEPPIPHDKVVVDEGQDQEGPEEKKPPPRLPDEGDPAGRGQGAPPLPESEKEKQEPERGG------------EGKRP 561
Cdd:PTZ00121 1515 AKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNmalrkaeeakkaEEARI 1594
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137  562 GQVLAVGETEHPQKVPEANGQPPVQPRKEDSRPGNRDPQPAAQARDSVELKALAADDGR----EPAQKAGGALWKPVESA 637
Cdd:PTZ00121 1595 EEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKkaeeENKIKAAEEAKKAEEDK 1674
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137  638 AESDAGGKAglPVQRPEAAEQREKKEAEQQGGDQAGSKL-EEAGRAEMLDHAVLLQVIQEQQVQQKRLLDQQEKLLAVIE 716
Cdd:PTZ00121 1675 KKAEEAKKA--EEDEKKAAEALKKEAEEAKKAEELKKKEaEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKD 1752
                         330       340       350
                  ....*....|....*....|....*....|....*....
gi 258645137  717 EQHKEIRQQRQEgEEDKPKPDVQPEPGVAVLRGQEEEAE 755
Cdd:PTZ00121 1753 EEEKKKIAHLKK-EEEKKAEEIRKEKEAVIEEELDEEDE 1790
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
505-769 4.27e-04

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 44.60  E-value: 4.27e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137   505 KVVVDEGQD--QEGPEEKKPPPRLPDEGDPAGRGQGAPPLPESEKEKQEPERGGEGKRPGQVLAVGETEHPQKVPEANGQ 582
Cdd:TIGR00927  632 KGDVAEAEHtgERTGEEGERPTEAEGENGEESGGEAEQEGETETKGENESEGEIPAERKGEQEGEGEIEAKEADHKGETE 711
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137   583 PPVQPRKEDSRPGNRDPQPAAQARDSVELKalaADDGREPAQKAggalwKPVESAAESDAGGKAGLPVQRPEAAEQREKK 662
Cdd:TIGR00927  712 AEEVEHEGETEAEGTEDEGEIETGEEGEEV---EDEGEGEAEGK-----HEVETEGDRKETEHEGETEAEGKEDEDEGEI 783
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137   663 EAEQQG---GDQAGSKLEEAGRAEMLDHAVLLQVIQEQQVQQKRLLDQQEKlLAVIEEQHKEIRQQRQ--EGEEDKPKPD 737
Cdd:TIGR00927  784 QAGEDGemkGDEGAEGKVEHEGETEAGEKDEHEGQSETQADDTEVKDETGE-QELNAENQGEAKQDEKgvDGGGGSDGGD 862
                          250       260       270
                   ....*....|....*....|....*....|..
gi 258645137   738 VQPEPGVAVLRGQEEEAEHAGETLGDDPSQPL 769
Cdd:TIGR00927  863 SEEEEEEEEEEEEEEEEEEEEEEEEEENEEPL 894
PHA03169 PHA03169
hypothetical protein; Provisional
461-628 7.09e-04

hypothetical protein; Provisional


Pssm-ID: 223003 [Multi-domain]  Cd Length: 413  Bit Score: 43.42  E-value: 7.09e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137  461 GPVDVPGGEAPKEKQEAAQLDRPGQGIAVPMGEAHRHEPPIPHDkvvvDEGQDQEGPEEKKPPPRlPDEGDPAGRGQGAP 540
Cdd:PHA03169  111 AEELASGLSPENTSGSSPESPASHSPPPSPPSHPGPHEPAPPES----HNPSPNQQPSSFLQPSH-EDSPEEPEPPTSEP 185
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137  541 PlPESEK--EKQEPERGGEGKRPGQVLAVGETEHPQKVPEANGQPPVQPRKEDSRPGNRDPQPAAQARDSVELKalaadd 618
Cdd:PHA03169  186 E-PDSPGppQSETPTSSPPPQSPPDEPGEPQSPTPQQAPSPNTQQAVEHEDEPTEPEREGPPFPGHRSHSYTVV------ 258
                         170
                  ....*....|
gi 258645137  619 GREPAQKAGG 628
Cdd:PHA03169  259 GWKPSTRPGG 268
PRK10905 PRK10905
cell division protein DamX; Validated
526-646 8.71e-04

cell division protein DamX; Validated


Pssm-ID: 236792 [Multi-domain]  Cd Length: 328  Bit Score: 42.62  E-value: 8.71e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137  526 LPDEgdPAG----RGQGAPPlpesEKEKQEPERGGEGKRPGQVLAVGETEHPQKVPEANGQPPVQP--RKEDSRPGNRDP 599
Cdd:PRK10905  123 LPTE--PATvapvRNGNASR----QTAKTQTAERPATTRPARKQAVIEPKKPQATAKTEPKPVAQTpkRTEPAAPVASTK 196
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 258645137  600 QPAAQARDSVELKALAAddgrePAQKAggalwKPVESAAESDAGGKA 646
Cdd:PRK10905  197 APAATSTPAPKETATTA-----PVQTA-----SPAQTTATPAAGGKT 233
PHA03418 PHA03418
hypothetical E4 protein; Provisional
500-598 3.29e-03

hypothetical E4 protein; Provisional


Pssm-ID: 177646 [Multi-domain]  Cd Length: 230  Bit Score: 40.49  E-value: 3.29e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137  500 PIPHDKVVVDEGQDQEGPEEKKPPPRLPDEGD---PAGRGQGAPPLPESEKEK---------QEPERGGEGKRPGQVLAV 567
Cdd:PHA03418   68 PNGHNKPPVTKQPGGEGTEEDHQAPLAADADDdprPGKRSKADEHGPAPGRAAlapfkldldQDPLHGDPDPPPGATGGQ 147
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 258645137  568 GET-----EHPQKVP-----EANGQPPVQPRKEDSRPGNRD 598
Cdd:PHA03418  148 GEEppeggEESQPPLgegegAVEGHPPPLPPAPEPKPHNGD 188
PHA03169 PHA03169
hypothetical protein; Provisional
444-675 4.23e-03

hypothetical protein; Provisional


Pssm-ID: 223003 [Multi-domain]  Cd Length: 413  Bit Score: 40.72  E-value: 4.23e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137  444 KLKPAEDKEVLEQAQIKGPVDvPGGEAPKEKQEAAQLDRPGQ----GIAVPMGEAHRH-EPPIPHDKVVVDEGQDQ---- 514
Cdd:PHA03169   43 AAKPAPPAPTTSGPQVRAVAE-QGHRQTESDTETAEESRHGEkeerGQGGPSGSGSESvGSPTPSPSGSAEELASGlspe 121
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137  515 -------EGPEEKKPPPRLPDEGDPAGRG-----QGAPPLPESEKEKQEPERGGEGKRPGQVLAVGETEHPQKVPEA-NG 581
Cdd:PHA03169  122 ntsgsspESPASHSPPPSPPSHPGPHEPAppeshNPSPNQQPSSFLQPSHEDSPEEPEPPTSEPEPDSPGPPQSETPtSS 201
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137  582 QPPVQPRKEDSRPGNRDPQ--PAAQARDSVELKALAADDGREPAQKAGGAL--WKPVESAAESDAGGKAGLPVQRPEAAE 657
Cdd:PHA03169  202 PPPQSPPDEPGEPQSPTPQqaPSPNTQQAVEHEDEPTEPEREGPPFPGHRShsYTVVGWKPSTRPGGVPKLCLRCTSHPS 281
                         250
                  ....*....|....*...
gi 258645137  658 QREKKEAEQQGGDQAGSK 675
Cdd:PHA03169  282 HRSRLPEGQQSEDKVPRK 299
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
432-653 5.01e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 40.92  E-value: 5.01e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137  432 DPVVVVAEDSQEKLKPAEDKEVLEQAQIKGPVDVPGGEAPKEKQEAAQLDRPGQGIAvPMGEAHRHEPPIPHDkvvvdeg 511
Cdd:PHA03307   52 AVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTP-PGPSSPDPPPPTPPP------- 123
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137  512 qdqEGPEEKKPPPR---LPDEGDPAGRGQGAPPLPESEKEkqEPERGGEGKRPGQVLA--VGETEHPQKVPEANGQPPVQ 586
Cdd:PHA03307  124 ---ASPPPSPAPDLsemLRPVGSPGPPPAASPPAAGASPA--AVASDAASSRQAALPLssPEETARAPSSPPAEPPPSTP 198
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 258645137  587 PRKEDSRPGNRDPQPAAQARDSvelkalAADDGREPAQKAGGALWKPVES-AAESDAGGKAGLPVQRP 653
Cdd:PHA03307  199 PAAASPRPPRRSSPISASASSP------APAPGRSAADDAGASSSDSSSSeSSGCGWGPENECPLPRP 260
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
404-678 5.37e-03

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 40.75  E-value: 5.37e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137   404 DLTQEARSghRGDAEGAMKVEAARLSVQDPVVVVAEDSQEKLKPAEDKEVLEQAQiKGpvDVPG-GEAPKEKQEAAQLDR 482
Cdd:TIGR00927  629 DLSKGDVA--EAEHTGERTGEEGERPTEAEGENGEESGGEAEQEGETETKGENES-EG--EIPAeRKGEQEGEGEIEAKE 703
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137   483 PGQGIAVPMGEAHRHEPPIPHDKVVVDEGQDQEGPEEKKPPPRLPDEGDPAGRGQGAPPLPESEKEKQEPERGGEGKrpG 562
Cdd:TIGR00927  704 ADHKGETEAEEVEHEGETEAEGTEDEGEIETGEEGEEVEDEGEGEAEGKHEVETEGDRKETEHEGETEAEGKEDEDE--G 781
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137   563 QVLAVGETEHP----QKVPEANGQPPVQPRKEDSRPGNRDPQPAAQARDSVELKALAADDGREPAQKaggalwkpvESAA 638
Cdd:TIGR00927  782 EIQAGEDGEMKgdegAEGKVEHEGETEAGEKDEHEGQSETQADDTEVKDETGEQELNAENQGEAKQD---------EKGV 852
                          250       260       270       280
                   ....*....|....*....|....*....|....*....|
gi 258645137   639 ESDAGGKAGLPVQRPEAAEQREKKEAEQQGGDQAGSKLEE 678
Cdd:TIGR00927  853 DGGGGSDGGDSEEEEEEEEEEEEEEEEEEEEEEEEEENEE 892
rne PRK10811
ribonuclease E; Reviewed
723-969 7.76e-03

ribonuclease E; Reviewed


Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 40.41  E-value: 7.76e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137  723 RQQRQEGEEDKPKPDVQPEPGVAvlrgqEEEAEHAGEtlgddPSQPLQPVLGAPRGRPAPsqdmgqhlpgeVKVLPGRDL 802
Cdd:PRK10811  849 RPQDVQVEEQREAEEVQVQPVVA-----EVPVAAAVE-----PVVSAPVVEAVAEVVEEP-----------VVVAEPQPE 907
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137  803 ADLPAGGSETEPQGAPIDlrEDPKAAIKAAGAGKELVPGDLEAVHKAAPPEVPKSPEKQVAKAVAGQRQDVFGEGSEERK 882
Cdd:PRK10811  908 EVVVVETTHPEVIAAPVT--EQPQVITESDVAVAQEVAEHAEPVVEPQDETADIEEAAETAEVVVAEPEVVAQPAAPVVA 985
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258645137  883 ETgkEAMAPGADTQKEAVQPLVGAEAKDTKSRQSGP-TKAPVqtqakfhpepqaifdtgqgshPEVRSEAPRAVH-IPPE 960
Cdd:PRK10811  986 EV--AAEVETVTAVEPEVAPAQVPEATVEHNHATAPmTRAPA---------------------PEYVPEAPRHSDwQRPT 1042

                  ....*....
gi 258645137  961 EQHKGKGGA 969
Cdd:PRK10811 1043 FAFEGKGAA 1051
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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