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Conserved domains on  [gi|281360006|ref|NP_001162694|]
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NADH dehydrogenase (ubiquinone) MNLL subunit, isoform D [Drosophila melanogaster]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
NADH_oxidored super family cl06878
MNLL subunit; This family consists of the MNLL subunits of NADH-ubiquinone oxidoreductase ...
 17-56 7.70e-13

MNLL subunit; This family consists of the MNLL subunits of NADH-ubiquinone oxidoreductase complex. NADH-ubiquinone oxidoreductase is involved in the transfer of electrons from NADH to the electron transport chain. This oxidation of NADH is coupled to proton transfer across the membrane, generating a proton motive force that is utilized for the synthesis of ATP. MNLL subunit is one of the many subunits found in the complex and it contains a mitochondrial import sequence. However, the role of MNLL subunit is unclear.


The actual alignment was detected with superfamily member pfam08040:

Pssm-ID: 462345  Cd Length: 56  Bit Score: 55.93  E-value: 7.70e-13
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|
gi 281360006  17 LGFAIGHFLDKKETERMTMFRDKSALYGRPAgSEGKAPSW 56
Cdd:pfam08040 17 MGFVIGWYLDRKNDEKLTAFRNKSMLYKREL-KPGEEVTW 55
 
Name Accession Description Interval E-value
NADH_oxidored pfam08040
MNLL subunit; This family consists of the MNLL subunits of NADH-ubiquinone oxidoreductase ...
 17-56 7.70e-13

MNLL subunit; This family consists of the MNLL subunits of NADH-ubiquinone oxidoreductase complex. NADH-ubiquinone oxidoreductase is involved in the transfer of electrons from NADH to the electron transport chain. This oxidation of NADH is coupled to proton transfer across the membrane, generating a proton motive force that is utilized for the synthesis of ATP. MNLL subunit is one of the many subunits found in the complex and it contains a mitochondrial import sequence. However, the role of MNLL subunit is unclear.


Pssm-ID: 462345  Cd Length: 56  Bit Score: 55.93  E-value: 7.70e-13
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|
gi 281360006  17 LGFAIGHFLDKKETERMTMFRDKSALYGRPAgSEGKAPSW 56
Cdd:pfam08040 17 MGFVIGWYLDRKNDEKLTAFRNKSMLYKREL-KPGEEVTW 55
 
Name Accession Description Interval E-value
NADH_oxidored pfam08040
MNLL subunit; This family consists of the MNLL subunits of NADH-ubiquinone oxidoreductase ...
 17-56 7.70e-13

MNLL subunit; This family consists of the MNLL subunits of NADH-ubiquinone oxidoreductase complex. NADH-ubiquinone oxidoreductase is involved in the transfer of electrons from NADH to the electron transport chain. This oxidation of NADH is coupled to proton transfer across the membrane, generating a proton motive force that is utilized for the synthesis of ATP. MNLL subunit is one of the many subunits found in the complex and it contains a mitochondrial import sequence. However, the role of MNLL subunit is unclear.


Pssm-ID: 462345  Cd Length: 56  Bit Score: 55.93  E-value: 7.70e-13
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|
gi 281360006  17 LGFAIGHFLDKKETERMTMFRDKSALYGRPAgSEGKAPSW 56
Cdd:pfam08040 17 MGFVIGWYLDRKNDEKLTAFRNKSMLYKREL-KPGEEVTW 55
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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