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Conserved domains on  [gi|295390587|ref|NP_001171324|]
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aspartyl/asparaginyl beta-hydroxylase isoform 7 [Mus musculus]

Protein Classification

Asp-B-Hydro_N domain-containing protein( domain architecture ID 12062539)

Asp-B-Hydro_N domain-containing protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Asp-B-Hydro_N pfam05279
Aspartyl beta-hydroxylase N-terminal region; This family includes the N-terminal regions of ...
25-79 2.61e-21

Aspartyl beta-hydroxylase N-terminal region; This family includes the N-terminal regions of the junctin, junctate and aspartyl beta-hydroxylase proteins. Junctate is an integral ER/SR membrane calcium binding protein, which comes from an alternatively spliced form of the same gene that generates aspartyl beta-hydroxylase and junctin. Aspartyl beta-hydroxylase catalyzes the post-translational hydroxylation of aspartic acid or asparagine residues contained within epidermal growth factor (EGF) domains of proteins.


:

Pssm-ID: 428406  Cd Length: 66  Bit Score: 84.51  E-value: 2.61e-21
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 295390587   25 FFTWFMVIALLGVWTSVAVVWFDLVDYEEVLGKLGVYDADGDGDFDVDDAKVLLE 79
Cdd:pfam05279  12 FFTWFMVIALLGVWTSVAVVWFDLVDYEEVLGKLGVYDADGDGDFDVDDAKVLLG 66
MDN1 super family cl34967
Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal ...
96-197 5.92e-03

Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis];


The actual alignment was detected with superfamily member COG5271:

Pssm-ID: 227596 [Multi-domain]  Cd Length: 4600  Bit Score: 38.06  E-value: 5.92e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295390587   96 ERSPSERTFPPEEEAETHAELEEQAPEGADLEADGLAGEPQPEVEDFLTVTDSDDRFEDLEPGTVHEEI--EDTYHVEDT 173
Cdd:COG5271  4064 EDGFEENVQENEESTEDGVKSDEELEQGEVPEDQAIDNHPKMDAKSTFASAEADEENTDKGIVGENEELgeEDGVRGNGT 4143
                          90       100
                  ....*....|....*....|....
gi 295390587  174 ASQNHPNDMEEMTNEQENSDPSEA 197
Cdd:COG5271  4144 ADGEFEQVQEDTSTPKEAMSEADR 4167
 
Name Accession Description Interval E-value
Asp-B-Hydro_N pfam05279
Aspartyl beta-hydroxylase N-terminal region; This family includes the N-terminal regions of ...
25-79 2.61e-21

Aspartyl beta-hydroxylase N-terminal region; This family includes the N-terminal regions of the junctin, junctate and aspartyl beta-hydroxylase proteins. Junctate is an integral ER/SR membrane calcium binding protein, which comes from an alternatively spliced form of the same gene that generates aspartyl beta-hydroxylase and junctin. Aspartyl beta-hydroxylase catalyzes the post-translational hydroxylation of aspartic acid or asparagine residues contained within epidermal growth factor (EGF) domains of proteins.


Pssm-ID: 428406  Cd Length: 66  Bit Score: 84.51  E-value: 2.61e-21
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 295390587   25 FFTWFMVIALLGVWTSVAVVWFDLVDYEEVLGKLGVYDADGDGDFDVDDAKVLLE 79
Cdd:pfam05279  12 FFTWFMVIALLGVWTSVAVVWFDLVDYEEVLGKLGVYDADGDGDFDVDDAKVLLG 66
MDN1 COG5271
Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal ...
96-197 5.92e-03

Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis];


Pssm-ID: 227596 [Multi-domain]  Cd Length: 4600  Bit Score: 38.06  E-value: 5.92e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295390587   96 ERSPSERTFPPEEEAETHAELEEQAPEGADLEADGLAGEPQPEVEDFLTVTDSDDRFEDLEPGTVHEEI--EDTYHVEDT 173
Cdd:COG5271  4064 EDGFEENVQENEESTEDGVKSDEELEQGEVPEDQAIDNHPKMDAKSTFASAEADEENTDKGIVGENEELgeEDGVRGNGT 4143
                          90       100
                  ....*....|....*....|....
gi 295390587  174 ASQNHPNDMEEMTNEQENSDPSEA 197
Cdd:COG5271  4144 ADGEFEQVQEDTSTPKEAMSEADR 4167
 
Name Accession Description Interval E-value
Asp-B-Hydro_N pfam05279
Aspartyl beta-hydroxylase N-terminal region; This family includes the N-terminal regions of ...
25-79 2.61e-21

Aspartyl beta-hydroxylase N-terminal region; This family includes the N-terminal regions of the junctin, junctate and aspartyl beta-hydroxylase proteins. Junctate is an integral ER/SR membrane calcium binding protein, which comes from an alternatively spliced form of the same gene that generates aspartyl beta-hydroxylase and junctin. Aspartyl beta-hydroxylase catalyzes the post-translational hydroxylation of aspartic acid or asparagine residues contained within epidermal growth factor (EGF) domains of proteins.


Pssm-ID: 428406  Cd Length: 66  Bit Score: 84.51  E-value: 2.61e-21
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 295390587   25 FFTWFMVIALLGVWTSVAVVWFDLVDYEEVLGKLGVYDADGDGDFDVDDAKVLLE 79
Cdd:pfam05279  12 FFTWFMVIALLGVWTSVAVVWFDLVDYEEVLGKLGVYDADGDGDFDVDDAKVLLG 66
MDN1 COG5271
Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal ...
96-197 5.92e-03

Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis];


Pssm-ID: 227596 [Multi-domain]  Cd Length: 4600  Bit Score: 38.06  E-value: 5.92e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295390587   96 ERSPSERTFPPEEEAETHAELEEQAPEGADLEADGLAGEPQPEVEDFLTVTDSDDRFEDLEPGTVHEEI--EDTYHVEDT 173
Cdd:COG5271  4064 EDGFEENVQENEESTEDGVKSDEELEQGEVPEDQAIDNHPKMDAKSTFASAEADEENTDKGIVGENEELgeEDGVRGNGT 4143
                          90       100
                  ....*....|....*....|....
gi 295390587  174 ASQNHPNDMEEMTNEQENSDPSEA 197
Cdd:COG5271  4144 ADGEFEQVQEDTSTPKEAMSEADR 4167
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.20
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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