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Conserved domains on  [gi|329112520|ref|NP_001179361|]
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RNA polymerase I-specific transcription initiation factor RRN3 [Bos taurus]

Protein Classification

RNA polymerase I-specific transcription initiation factor RRN3 family protein( domain architecture ID 10526375)

RNA polymerase I-specific transcription initiation factor RRN3 family protein similar to human RRN3 that is required for efficient transcription initiation by RNA polymerase I, and for the formation of the competent preinitiation complex (PIC).

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
RRN3 pfam05327
RNA polymerase I specific transcription initiation factor RRN3; This family consists of ...
 60-585 2.99e-149

RNA polymerase I specific transcription initiation factor RRN3; This family consists of several eukaryotic proteins which are homologous to the yeast RRN3 protein. RRN3 is one of the RRN genes specifically required for the transcription of rDNA by RNA polymerase I (Pol I) in Saccharomyces cerevisiae.


:

Pssm-ID: 461623  Cd Length: 548  Bit Score: 443.20  E-value: 2.99e-149
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329112520   60 LLKYKKGETNDFELLKNQLS-----DPEIKDDQIINWLLEFRSSIMYLTKDFEQLINILLRLKWLNRSQTVVEEYLSFLG 134
Cdd:pfam05327  16 LEEHEKGDSEQYDELKEQFSpdpesPDAPSTALLKQLLKALSSNVSRLDRSCSGLVEAILSLSWLGRDESFVKAYIRFLG 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329112520  135 NLVSAQTVFLRPCLSMIASHFVPPRVVIKEGDVDVSDSDDEDenlpanFDTCHRALQIIARYVPSTPWFLMPILVEKFPF 214
Cdd:pfam05327  96 VLASAHPKYLSLVLSMLVSNFTPQPESSGRLPGYPPVTRREV------YERVHEALKYILRLIPTAPSVLLPILSRKFPH 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329112520  215 VRKSERTLECYIHNLLRISVYFPTLRHEILELVVEKLLKLDVnasrQ---DIEDAEE---------TAAQTGGGADATEA 282
Cdd:pfam05327 170 KRDSKKAQVTYIRNLLRLTEYCPELGSDILALIIERLIKIDV----EiqvELEDLDDdedeelleqLDEDDDDDDDDDSD 245

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329112520  283 LFNMDEDEEADHETKADPGRLDQMVHPMAERLDILLSLLLSYIKDVCY--VDGKIDNNKTKDLYRDLITIFDKLLLPTHA 360
Cdd:pfam05327 246 DDSDSSDDGLDDDEEDDEVQRIKKIKELVEKLDAILDLLFEHLDSKFSsgSPEELNEGEGVEVFNTLLSLFKSTILPTYR 325

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329112520  361 SCHVQFFMFYLCSFKLGFAEAFLEHLWKKLQDPNNPAIIRQAAANYIGSFLARAKFIPLITVKSCLDLLVNWLHVYLNNQ 440
Cdd:pfam05327 326 SRHTQFLLFHFSQLSPELMDSFLGTLIDIAFDPNEPAITRQAAAAYLASFVARAKFVSRSQVRFVLSYLCDWLNRYVDER 405

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329112520  441 DSGTKAfCDVALHGPFYSACQAVFYTFVFRHKQLL---SGNLKEGLRYLQSLN--FERIVMSQLNPLKICLPSVVNFFAA 515
Cdd:pfam05327 406 EEECRG-PDLKRHGVFYAVCQALLYIFCFRWRDLTdadDDEEGGDLEWLPGLDefLQRAIYSKLNPLKVCSPNVVTEFAR 484

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329112520  516 ITNKYQLVFCYTLIERNNRqmlpviRNTAGGDSVQTcTNPLDTFFPFDPCVLKRSKKFIDPLYQIWEDMS 585
Cdd:pfam05327 485 IAHHLQFAYCFSIIESNKR------EETAGTATGQE-FEQLDAYFPFDPYLLPRSKRWIEPDYVEWSEVA 547
 
Name Accession Description Interval E-value
RRN3 pfam05327
RNA polymerase I specific transcription initiation factor RRN3; This family consists of ...
 60-585 2.99e-149

RNA polymerase I specific transcription initiation factor RRN3; This family consists of several eukaryotic proteins which are homologous to the yeast RRN3 protein. RRN3 is one of the RRN genes specifically required for the transcription of rDNA by RNA polymerase I (Pol I) in Saccharomyces cerevisiae.


Pssm-ID: 461623  Cd Length: 548  Bit Score: 443.20  E-value: 2.99e-149
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329112520   60 LLKYKKGETNDFELLKNQLS-----DPEIKDDQIINWLLEFRSSIMYLTKDFEQLINILLRLKWLNRSQTVVEEYLSFLG 134
Cdd:pfam05327  16 LEEHEKGDSEQYDELKEQFSpdpesPDAPSTALLKQLLKALSSNVSRLDRSCSGLVEAILSLSWLGRDESFVKAYIRFLG 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329112520  135 NLVSAQTVFLRPCLSMIASHFVPPRVVIKEGDVDVSDSDDEDenlpanFDTCHRALQIIARYVPSTPWFLMPILVEKFPF 214
Cdd:pfam05327  96 VLASAHPKYLSLVLSMLVSNFTPQPESSGRLPGYPPVTRREV------YERVHEALKYILRLIPTAPSVLLPILSRKFPH 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329112520  215 VRKSERTLECYIHNLLRISVYFPTLRHEILELVVEKLLKLDVnasrQ---DIEDAEE---------TAAQTGGGADATEA 282
Cdd:pfam05327 170 KRDSKKAQVTYIRNLLRLTEYCPELGSDILALIIERLIKIDV----EiqvELEDLDDdedeelleqLDEDDDDDDDDDSD 245

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329112520  283 LFNMDEDEEADHETKADPGRLDQMVHPMAERLDILLSLLLSYIKDVCY--VDGKIDNNKTKDLYRDLITIFDKLLLPTHA 360
Cdd:pfam05327 246 DDSDSSDDGLDDDEEDDEVQRIKKIKELVEKLDAILDLLFEHLDSKFSsgSPEELNEGEGVEVFNTLLSLFKSTILPTYR 325

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329112520  361 SCHVQFFMFYLCSFKLGFAEAFLEHLWKKLQDPNNPAIIRQAAANYIGSFLARAKFIPLITVKSCLDLLVNWLHVYLNNQ 440
Cdd:pfam05327 326 SRHTQFLLFHFSQLSPELMDSFLGTLIDIAFDPNEPAITRQAAAAYLASFVARAKFVSRSQVRFVLSYLCDWLNRYVDER 405

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329112520  441 DSGTKAfCDVALHGPFYSACQAVFYTFVFRHKQLL---SGNLKEGLRYLQSLN--FERIVMSQLNPLKICLPSVVNFFAA 515
Cdd:pfam05327 406 EEECRG-PDLKRHGVFYAVCQALLYIFCFRWRDLTdadDDEEGGDLEWLPGLDefLQRAIYSKLNPLKVCSPNVVTEFAR 484

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329112520  516 ITNKYQLVFCYTLIERNNRqmlpviRNTAGGDSVQTcTNPLDTFFPFDPCVLKRSKKFIDPLYQIWEDMS 585
Cdd:pfam05327 485 IAHHLQFAYCFSIIESNKR------EETAGTATGQE-FEQLDAYFPFDPYLLPRSKRWIEPDYVEWSEVA 547
 
Name Accession Description Interval E-value
RRN3 pfam05327
RNA polymerase I specific transcription initiation factor RRN3; This family consists of ...
 60-585 2.99e-149

RNA polymerase I specific transcription initiation factor RRN3; This family consists of several eukaryotic proteins which are homologous to the yeast RRN3 protein. RRN3 is one of the RRN genes specifically required for the transcription of rDNA by RNA polymerase I (Pol I) in Saccharomyces cerevisiae.


Pssm-ID: 461623  Cd Length: 548  Bit Score: 443.20  E-value: 2.99e-149
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329112520   60 LLKYKKGETNDFELLKNQLS-----DPEIKDDQIINWLLEFRSSIMYLTKDFEQLINILLRLKWLNRSQTVVEEYLSFLG 134
Cdd:pfam05327  16 LEEHEKGDSEQYDELKEQFSpdpesPDAPSTALLKQLLKALSSNVSRLDRSCSGLVEAILSLSWLGRDESFVKAYIRFLG 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329112520  135 NLVSAQTVFLRPCLSMIASHFVPPRVVIKEGDVDVSDSDDEDenlpanFDTCHRALQIIARYVPSTPWFLMPILVEKFPF 214
Cdd:pfam05327  96 VLASAHPKYLSLVLSMLVSNFTPQPESSGRLPGYPPVTRREV------YERVHEALKYILRLIPTAPSVLLPILSRKFPH 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329112520  215 VRKSERTLECYIHNLLRISVYFPTLRHEILELVVEKLLKLDVnasrQ---DIEDAEE---------TAAQTGGGADATEA 282
Cdd:pfam05327 170 KRDSKKAQVTYIRNLLRLTEYCPELGSDILALIIERLIKIDV----EiqvELEDLDDdedeelleqLDEDDDDDDDDDSD 245

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329112520  283 LFNMDEDEEADHETKADPGRLDQMVHPMAERLDILLSLLLSYIKDVCY--VDGKIDNNKTKDLYRDLITIFDKLLLPTHA 360
Cdd:pfam05327 246 DDSDSSDDGLDDDEEDDEVQRIKKIKELVEKLDAILDLLFEHLDSKFSsgSPEELNEGEGVEVFNTLLSLFKSTILPTYR 325

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329112520  361 SCHVQFFMFYLCSFKLGFAEAFLEHLWKKLQDPNNPAIIRQAAANYIGSFLARAKFIPLITVKSCLDLLVNWLHVYLNNQ 440
Cdd:pfam05327 326 SRHTQFLLFHFSQLSPELMDSFLGTLIDIAFDPNEPAITRQAAAAYLASFVARAKFVSRSQVRFVLSYLCDWLNRYVDER 405

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329112520  441 DSGTKAfCDVALHGPFYSACQAVFYTFVFRHKQLL---SGNLKEGLRYLQSLN--FERIVMSQLNPLKICLPSVVNFFAA 515
Cdd:pfam05327 406 EEECRG-PDLKRHGVFYAVCQALLYIFCFRWRDLTdadDDEEGGDLEWLPGLDefLQRAIYSKLNPLKVCSPNVVTEFAR 484

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 329112520  516 ITNKYQLVFCYTLIERNNRqmlpviRNTAGGDSVQTcTNPLDTFFPFDPCVLKRSKKFIDPLYQIWEDMS 585
Cdd:pfam05327 485 IAHHLQFAYCFSIIESNKR------EETAGTATGQE-FEQLDAYFPFDPYLLPRSKRWIEPDYVEWSEVA 547
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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