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Conserved domains on  [gi|308081799|ref|NP_001183972|]
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galectin-3 [Canis lupus familiaris]

Protein Classification

galectin family protein( domain architecture ID 10049222)

galectin family protein may exclusively bind beta-galactosides such as lactose in a manner independent of metal ions

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GLECT cd00070
Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as ...
 154-281 4.04e-52

Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as lactose, and does not require metal ions for activity. GLECT domains occur as homodimers or tandemly repeated domains. They are developmentally regulated and may be involved in differentiation, cell-cell interaction and cellular regulation.


:

Pssm-ID: 238025  Cd Length: 127  Bit Score: 166.66  E-value: 4.04e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799 154 PYDLPLPGGVKPRMLITILGTVRPSANRLALDFKRGN-DVAFHFNPRFNEDnkrVIVCNTKLDNIWGKEERQAAFPFESG 232
Cdd:cd00070    1 PYKLPLPGGLKPGSTLTVKGRVLPNAKRFSINLGTGSsDIALHFNPRFDEN---VIVRNSFLNGNWGPEERSGGFPFQPG 77

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 308081799 233 KPFKIQVLVESDHFKVAVNDAHLLQYNHRMKnLPEISKLGISGDIDLTS 281
Cdd:cd00070   78 QPFELTILVEEDKFQIFVNGQHFFSFPHRLP-LESIDYLSINGDVSLTS 125
PRK07764 super family cl35613
DNA polymerase III subunits gamma and tau; Validated
 13-150 5.19e-11

DNA polymerase III subunits gamma and tau; Validated


The actual alignment was detected with superfamily member PRK07764:

Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 63.08  E-value: 5.19e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799  13 GSGNPNPQGWPGPWGNQPAGAGGYPGAsyPGAYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGYPG 92
Cdd:PRK07764 591 APGAAGGEGPPAPASSGPPEEAARPAA--PAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDG 668

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 308081799  93 QAPPGTYPGPTAPayPGPTAPGTQPGQPSGPGAYPPPGQPSAPGAYPAAGPFGIPAGP 150
Cdd:PRK07764 669 WPAKAGGAAPAAP--PPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQA 724
 
Name Accession Description Interval E-value
GLECT cd00070
Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as ...
 154-281 4.04e-52

Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as lactose, and does not require metal ions for activity. GLECT domains occur as homodimers or tandemly repeated domains. They are developmentally regulated and may be involved in differentiation, cell-cell interaction and cellular regulation.


Pssm-ID: 238025  Cd Length: 127  Bit Score: 166.66  E-value: 4.04e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799 154 PYDLPLPGGVKPRMLITILGTVRPSANRLALDFKRGN-DVAFHFNPRFNEDnkrVIVCNTKLDNIWGKEERQAAFPFESG 232
Cdd:cd00070    1 PYKLPLPGGLKPGSTLTVKGRVLPNAKRFSINLGTGSsDIALHFNPRFDEN---VIVRNSFLNGNWGPEERSGGFPFQPG 77

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 308081799 233 KPFKIQVLVESDHFKVAVNDAHLLQYNHRMKnLPEISKLGISGDIDLTS 281
Cdd:cd00070   78 QPFELTILVEEDKFQIFVNGQHFFSFPHRLP-LESIDYLSINGDVSLTS 125
Gal-bind_lectin smart00908
Galactoside-binding lectin; Animal lectins display a wide variety of architectures. They are ...
 160-281 8.99e-51

Galactoside-binding lectin; Animal lectins display a wide variety of architectures. They are classified according to the carbohydrate-recognition domain (CRD) of which there are two main types, S-type and C-type. Galectins (previously S-lectins) bind exclusively beta-galactosides like lactose. They do not require metal ions for activity. Galectins are found predominantly, but not exclusively in mammals. Their function is unclear. They are developmentally regulated and may be involved in differentiation, cellular regulation and tissue construction.


Pssm-ID: 214904  Cd Length: 122  Bit Score: 163.15  E-value: 8.99e-51
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799   160 PGGVKPRMLITILGTVRPSANRLALDFKRG--NDVAFHFNPRFNEdnkRVIVCNTKLDNIWGKEERQAAFPFESGKPFKI 237
Cdd:smart00908   1 PGGLSPGSSITIRGIVLPDAKRFSINLQCGpnADIALHFNPRFDE---GTIVRNSKQNGKWGKEERSGGFPFQPGQPFEL 77

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....
gi 308081799   238 QVLVESDHFKVAVNDAHLLQYNHRMKnLPEISKLGISGDIDLTS 281
Cdd:smart00908  78 EILVEEDEFKVAVNGQHFLEFPHRLP-LESIDTLEISGDVQLTS 120
Gal-bind_lectin pfam00337
Galactoside-binding lectin; This family contains galactoside binding lectins. The family also ...
 160-281 8.69e-46

Galactoside-binding lectin; This family contains galactoside binding lectins. The family also includes enzymes such as human eosinophil lysophospholipase (EC:3.1.1.5).


Pssm-ID: 459768  Cd Length: 124  Bit Score: 150.48  E-value: 8.69e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799  160 PGGVKPRMLITILGTVRPSANRLALDFKRG----NDVAFHFNPRFNEDnkrVIVCNTKLDNIWGKEERQAAFPFESGKPF 235
Cdd:pfam00337   1 PGGLQPGSSLTIKGIVLPDAQRFSINLQTGvgpsDDIALHFNPRFDEN---VIVRNSRQNGQWGQEEREGGFPFQPGQPF 77

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 308081799  236 KIQVLVESDHFKVAVNDAHLLQYNHRMKNlPEISKLGISGDIDLTS 281
Cdd:pfam00337  78 ELTILVGDDHFKIYVNGQHFTTFKHRLPP-EDIDALQVRGDVKLTS 122
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 13-150 5.19e-11

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 63.08  E-value: 5.19e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799  13 GSGNPNPQGWPGPWGNQPAGAGGYPGAsyPGAYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGYPG 92
Cdd:PRK07764 591 APGAAGGEGPPAPASSGPPEEAARPAA--PAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDG 668

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 308081799  93 QAPPGTYPGPTAPayPGPTAPGTQPGQPSGPGAYPPPGQPSAPGAYPAAGPFGIPAGP 150
Cdd:PRK07764 669 WPAKAGGAAPAAP--PPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQA 724
Glutenin_hmw pfam03157
High molecular weight glutenin subunit; Members of this family include high molecular weight ...
 29-135 2.37e-06

High molecular weight glutenin subunit; Members of this family include high molecular weight subunits of glutenin. This group of gluten proteins is thought to be largely responsible for the elastic properties of gluten, and hence, doughs. Indeed, glutenin high molecular weight subunits are classified as elastomeric proteins, because the glutenin network can withstand significant deformations without breaking, and return to the original conformation when the stress is removed. Elastomeric proteins differ considerably in amino acid sequence, but they are all polymers whose subunits consist of elastomeric domains, composed of repeated motifs, and non-elastic domains that mediate cross-linking between the subunits. The elastomeric domain motifs are all rich in glycine residues in addition to other hydrophobic residues. High molecular weight glutenin subunits have an extensive central elastomeric domain, flanked by two terminal non-elastic domains that form disulphide cross-links. The central elastomeric domain is characterized by the following three repeated motifs: PGQGQQ, GYYPTS[P/L]QQ, GQQ. It possesses overlapping beta-turns within and between the repeated motifs, and assumes a regular helical secondary structure with a diameter of approx. 1.9 nm and a pitch of approx. 1.5 nm.


Pssm-ID: 367362 [Multi-domain]  Cd Length: 786  Bit Score: 48.79  E-value: 2.37e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799   29 QPAGAGGYPGASYPGA--YPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGTYpgPTAPA 106
Cdd:pfam03157 441 QQPGQGQQPGQEQPGQgqQPGQGQQGQQPGQPEQGQQPGQGQPGYYPTSPQQSGQGQQLGQWQQQGQGQPGYY--PTSPL 518

                          90       100
                  ....*....|....*....|....*....
gi 308081799  107 YPGPTAPGTQPGQPSGPGAYPPPGQPSAP 135
Cdd:pfam03157 519 QPGQGQPGYYPTSPQQPGQGQQLGQLQQP 547
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 15-150 8.24e-06

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 46.82  E-value: 8.24e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799  15 GNPNPQGWPGPWGnqPAGAGGYPGASYPGAYPGQAPPG--GYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGYPG 92
Cdd:NF038329 198 GETGPAGEQGPAG--PAGPDGEAGPAGEDGPAGPAGDGqqGPDGDPGPTGEDGPQGPDGPAGKDGPRGDRGEAGPDGPDG 275

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 308081799  93 QAPPGTYPGPTAP-------AYPGPTAPGTQPGQPSGPGAYPPPGQPSAPGAYPAAGPFGIPAGP 150
Cdd:NF038329 276 KDGERGPVGPAGKdgqngkdGLPGKDGKDGQNGKDGLPGKDGKDGQPGKDGLPGKDGKDGQPGKP 340
Chi1 COG3469
Chitinase [Carbohydrate transport and metabolism];
12-163 8.41e-06

Chitinase [Carbohydrate transport and metabolism];


Pssm-ID: 442692 [Multi-domain]  Cd Length: 534  Bit Score: 46.67  E-value: 8.41e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799  12 SGSGNPNPQGWPGPWGNQPAGAGGYPGASYPGAYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGYP 91
Cdd:COG3469   65 AASSTAATSSTTSTTATATAAAAAATSTSATLVATSTASGANTGTSTVTTTSTGAGSVTSTTSSTAGSTTTSGASATSSA 144

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 308081799  92 GQAPPGTYPGPTAPAYPGPTAPGTQPGQPSGPGAYPPPGQPSAPGAYPAAGPFGIPAGPLTVPYDLPLPGGV 163
Cdd:COG3469  145 GSTTTTTTVSGTETATGGTTTTSTTTTTTSASTTPSATTTATATTASGATTPSATTTATTTGPPTPGLPKHV 216
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 15-150 4.57e-05

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 44.51  E-value: 4.57e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799  15 GNPNPQGWPGPWGNQ----PAGAGGYPGASYPGAYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGY 90
Cdd:NF038329 126 GPAGPAGEQGPRGDRgetgPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGEAGAKGPAGEKGPQGPRGETGPAGE 205

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 308081799  91 P-GQAPPG--------TYPGPTAPAYPGPTAPGTQPGQPSGPGAYPPPGQPSAPGAYPAAGPFGiPAGP 150
Cdd:NF038329 206 QgPAGPAGpdgeagpaGEDGPAGPAGDGQQGPDGDPGPTGEDGPQGPDGPAGKDGPRGDRGEAG-PDGP 273
PABP-1234 TIGR01628
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins ...
 19-143 6.41e-04

polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins recognize the poly-A of mRNA and consists of four tandem RNA recognition domains at the N-terminus (rrm: pfam00076) followed by a PABP-specific domain (pfam00658) at the C-terminus. The protein is involved in the transport of mRNA's from the nucleus to the cytoplasm. There are four paralogs in Homo sapiens which are expressed in testis, platelets, broadly expressed and of unknown tissue range.


Pssm-ID: 130689 [Multi-domain]  Cd Length: 562  Bit Score: 40.95  E-value: 6.41e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799   19 PQGWPGPWGNQPAGAGGYPgasypgAYPGQAPPGGYPGQapPGGYPGQAPpggypgqAPPGGYPG-QAPPGGYPGQAPPG 97
Cdd:TIGR01628 380 PRMRQLPMGSPMGGAMGQP------PYYGQGPQQQFNGQ--PLGWPRMSM-------MPTPMGPGgPLRPNGLAPMNAVR 444

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 308081799   98 TyPGPTAPAYPGPTAPGTQPGQPSGPGAYPPPGQPSAPGAYPAAGP 143
Cdd:TIGR01628 445 A-PSRNAQNAAQKPPMQPVMYPPNYQSLPLSQDLPQPQSTASQGGQ 489
SAV_2336_NTERM NF041121
SAV_2336 family N-terminal domain; This HMM describes an N-terminal domain shared by SAV_2336 ...
 67-185 2.23e-03

SAV_2336 family N-terminal domain; This HMM describes an N-terminal domain shared by SAV_2336 (BAC70047.1) whose C-terminal region suggests restriction enzyme activity (PMID: 18456708), and with other proteins with unrelated C-terminal regions. A member protein was also identified in a kanamycin biosynthetic gene cluster (PMID:16766657), while N-terminal regions of two other member proteins were named Trypco1 in a bioinformatic study (PMID:32101166) of predicted bacterial conflict systems.


Pssm-ID: 469044 [Multi-domain]  Cd Length: 473  Bit Score: 39.22  E-value: 2.23e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799  67 APPGGYPGQAPPGGYPGQAPPGGYPGQAPPGTYPGPTAPAypGPTAPGTQPGQPSGPGAYPPPGQPSAPGAypaAGPFGI 146
Cdd:NF041121  19 AAPPSPEGPAPTAASQPATPPPPAAPPSPPGDPPEPPAPE--PAPLPAPYPGSLAPPPPPPPGPAGAAPGA---ALPVRV 93

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 308081799 147 PAGPltvpydlPLPGGVK-PRMLITILGTVrPSANRLALD 185
Cdd:NF041121  94 PAPP-------ALPNPLElARALRPLKRRV-PSPRRVELD 125
KREPA2 cd23959
Kinetoplastid RNA Editing Protein A2 (KREPA2); The KREPA2 (TbMP63) protein is a component of ...
 48-152 7.93e-03

Kinetoplastid RNA Editing Protein A2 (KREPA2); The KREPA2 (TbMP63) protein is a component of the parasitic protozoan's KREPA RNA editing catalytic complex (RECC). Kinetoplastid RNA editing (KRE) proteins occur as pairs or sets of related proteins in multiple complexes. KREPA complex is composed of six components (KREPA1-6), which share a conserved C-terminal region containing an oligonucleotide-binding (OB)-fold-like domain. KREPAs are responsible for the site-specific insertion and deletion of U nucleotides in the kinetoplastid mitochondria pre-messenger RNA. Apart from the conserved C-terminal OB-fold domain, KREPA1, KREPA2, and KREPA3 contain two conserved C2H2 zinc-finger domains. KREPA2 and kinetoplastid RNA editing ligase 1 (KREL1) are specific for ligation post-U-deletion and are paralogous to KREL2 and KREPA1 that are specific for ligation post-U-insertion. KREPA2, is critical for RECC stability and KREL1 integration into the complex.


Pssm-ID: 467780 [Multi-domain]  Cd Length: 424  Bit Score: 37.54  E-value: 7.93e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799  48 QAPPGGYPGQAPpggYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQ-APPGTYPGPTAPAYPGPTAPGTQPGQPSGPGAY 126
Cdd:cd23959  143 QTAPVTPFGQLP---MFGQHPPPAKPLPAAAAAQQSSASPGEVASPfASGTVSASPFATATDTAPSSGAPDGFPAEASAP 219

                         90       100
                 ....*....|....*....|....*.
gi 308081799 127 PPPGQPSAPGAYPAAGPFGIPAGPLT 152
Cdd:cd23959  220 SPFAAPASAASFPAAPVANGEAATPT 245
 
Name Accession Description Interval E-value
GLECT cd00070
Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as ...
 154-281 4.04e-52

Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as lactose, and does not require metal ions for activity. GLECT domains occur as homodimers or tandemly repeated domains. They are developmentally regulated and may be involved in differentiation, cell-cell interaction and cellular regulation.


Pssm-ID: 238025  Cd Length: 127  Bit Score: 166.66  E-value: 4.04e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799 154 PYDLPLPGGVKPRMLITILGTVRPSANRLALDFKRGN-DVAFHFNPRFNEDnkrVIVCNTKLDNIWGKEERQAAFPFESG 232
Cdd:cd00070    1 PYKLPLPGGLKPGSTLTVKGRVLPNAKRFSINLGTGSsDIALHFNPRFDEN---VIVRNSFLNGNWGPEERSGGFPFQPG 77

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 308081799 233 KPFKIQVLVESDHFKVAVNDAHLLQYNHRMKnLPEISKLGISGDIDLTS 281
Cdd:cd00070   78 QPFELTILVEEDKFQIFVNGQHFFSFPHRLP-LESIDYLSINGDVSLTS 125
Gal-bind_lectin smart00908
Galactoside-binding lectin; Animal lectins display a wide variety of architectures. They are ...
 160-281 8.99e-51

Galactoside-binding lectin; Animal lectins display a wide variety of architectures. They are classified according to the carbohydrate-recognition domain (CRD) of which there are two main types, S-type and C-type. Galectins (previously S-lectins) bind exclusively beta-galactosides like lactose. They do not require metal ions for activity. Galectins are found predominantly, but not exclusively in mammals. Their function is unclear. They are developmentally regulated and may be involved in differentiation, cellular regulation and tissue construction.


Pssm-ID: 214904  Cd Length: 122  Bit Score: 163.15  E-value: 8.99e-51
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799   160 PGGVKPRMLITILGTVRPSANRLALDFKRG--NDVAFHFNPRFNEdnkRVIVCNTKLDNIWGKEERQAAFPFESGKPFKI 237
Cdd:smart00908   1 PGGLSPGSSITIRGIVLPDAKRFSINLQCGpnADIALHFNPRFDE---GTIVRNSKQNGKWGKEERSGGFPFQPGQPFEL 77

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....
gi 308081799   238 QVLVESDHFKVAVNDAHLLQYNHRMKnLPEISKLGISGDIDLTS 281
Cdd:smart00908  78 EILVEEDEFKVAVNGQHFLEFPHRLP-LESIDTLEISGDVQLTS 120
GLECT smart00276
Galectin; Galectin - galactose-binding lectin
 155-284 5.55e-50

Galectin; Galectin - galactose-binding lectin


Pssm-ID: 214596  Cd Length: 128  Bit Score: 161.24  E-value: 5.55e-50
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799   155 YDLPLPGGVKPRMLITILGTVRPSANRLALDF-KRGNDVAFHFNPRFNEDnkrVIVCNTKLDNIWGKEERQAAFPFESGK 233
Cdd:smart00276   1 FTLPIPGGLKPGQTLTVRGIVLPDAKRFSINLlTGGDDIALHFNPRFNEN---KIVCNSKLNGSWGSEEREGGFPFQPGQ 77

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|.
gi 308081799   234 PFKIQVLVESDHFKVAVNDAHLLQYNHRMKnLPEISKLGISGDIDLTSASY 284
Cdd:smart00276  78 PFDLTIIVQPDHFQIFVNGVHITTFPHRLP-LESIDYLSINGDVQLTSVSF 127
Gal-bind_lectin pfam00337
Galactoside-binding lectin; This family contains galactoside binding lectins. The family also ...
 160-281 8.69e-46

Galactoside-binding lectin; This family contains galactoside binding lectins. The family also includes enzymes such as human eosinophil lysophospholipase (EC:3.1.1.5).


Pssm-ID: 459768  Cd Length: 124  Bit Score: 150.48  E-value: 8.69e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799  160 PGGVKPRMLITILGTVRPSANRLALDFKRG----NDVAFHFNPRFNEDnkrVIVCNTKLDNIWGKEERQAAFPFESGKPF 235
Cdd:pfam00337   1 PGGLQPGSSLTIKGIVLPDAQRFSINLQTGvgpsDDIALHFNPRFDEN---VIVRNSRQNGQWGQEEREGGFPFQPGQPF 77

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 308081799  236 KIQVLVESDHFKVAVNDAHLLQYNHRMKNlPEISKLGISGDIDLTS 281
Cdd:pfam00337  78 ELTILVGDDHFKIYVNGQHFTTFKHRLPP-EDIDALQVRGDVKLTS 122
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 13-150 5.19e-11

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 63.08  E-value: 5.19e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799  13 GSGNPNPQGWPGPWGNQPAGAGGYPGAsyPGAYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGYPG 92
Cdd:PRK07764 591 APGAAGGEGPPAPASSGPPEEAARPAA--PAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDG 668

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 308081799  93 QAPPGTYPGPTAPayPGPTAPGTQPGQPSGPGAYPPPGQPSAPGAYPAAGPFGIPAGP 150
Cdd:PRK07764 669 WPAKAGGAAPAAP--PPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQA 724
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 10-162 2.31e-10

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 61.16  E-value: 2.31e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799  10 ALSGSGNPNPQGW-PGPWGNQPAGAGGYPGASYPGAYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPG 88
Cdd:PRK07764 594 AAGGEGPPAPASSgPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKA 673

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 308081799  89 GYPGQAPPGTYPGPTAPAYPGPTAPG----TQPGQPSGPGAYPPPGQPSAPGAyPAAGPFGIPAGPLTVPYDLPLPGG 162
Cdd:PRK07764 674 GGAAPAAPPPAPAPAAPAAPAGAAPAqpapAPAATPPAGQADDPAAQPPQAAQ-GASAPSPAADDPVPLPPEPDDPPD 750
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 9-165 1.69e-08

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 55.38  E-value: 1.69e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799   9 DALSGSGNPNPQGWPGPWGNQPAGAGGYPGASYPGAYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPG 88
Cdd:PRK07764 619 AAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAP 698

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 308081799  89 GYPGQAPPGTYPGPTAPAYPGPTAPGTQPGQPSGPGAYPPPGQPSAPGAYPAAGPFGIPAGPLTVPYDLPLPGGVKP 165
Cdd:PRK07764 699 AQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPP 775
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 24-173 2.04e-08

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 54.99  E-value: 2.04e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799  24 GPWGnQPAGAGGYPGASYPGAYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGTYPGPT 103
Cdd:PRK07764 665 GGDG-WPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPP 743

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 308081799 104 APAY-PGPTAPGTQPGQPSGPGAYPPPGQPSAPGAYPAAGPFGIPAGPLTVPYDLPLPGGVKPRMLITILG 173
Cdd:PRK07764 744 EPDDpPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEEMAEDDAPSMDDEDRRDAEEVAMELLEEELG 814
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
13-161 2.27e-08

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 54.88  E-value: 2.27e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799  13 GSGNPNPQGWPGPWGNQPAGAGGYPGASYPGAYPGQAPPGGYPGQAPPggypgQAPPGGYPGQAPPGGYPGQAPPGGYPG 92
Cdd:PRK12323 368 SGGGAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAA-----ARAVAAAPARRSPAPEALAAARQASAR 442

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 308081799  93 QAPPGTYPGPTAPAYPGPTAPGTQPGQPSGPGAYPPPGQPSAPGAYPAAGPFGIPAGPlTVPYDLPLPG 161
Cdd:PRK12323 443 GPGGAPAPAPAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPPWE-ELPPEFASPA 510
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 27-153 2.95e-08

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 54.61  E-value: 2.95e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799  27 GNQPAGAGGYPGASYPGAYPGQAPPGGYPGQAPPGGYPGQAPPGGY-PGQAPPGGYPGQAPPGGYPGQAPPGTYPGPTAP 105
Cdd:PRK07764 384 RLGVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPqPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPS 463

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 308081799 106 AYPGPTAPGTQPGQPSgPGAYPPPGQPSAPGAYPAAGPfGIPAGPLTV 153
Cdd:PRK07764 464 AQPAPAPAAAPEPTAA-PAPAPPAAPAPAAAPAAPAAP-AAPAGADDA 509
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 31-143 4.13e-08

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 54.22  E-value: 4.13e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799  31 AGAGGYPGASYPGAYPGQAPPGGYPGQ---APPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGTYPGPTAPAY 107
Cdd:PRK07764 586 AVVGPAPGAAGGEGPPAPASSGPPEEAarpAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDG 665

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 308081799 108 PGPTAPGTQPGQPSGPGAYPPPGQPSAPGAYPAAGP 143
Cdd:PRK07764 666 GDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQP 701
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 19-165 5.17e-08

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 53.84  E-value: 5.17e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799  19 PQGWPGPWGNQPAGAGGYPGASYPGAYPGQAPPGGYPGQ-----APPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQ 93
Cdd:PRK07764 618 PAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHvavpdASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAA 697

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 308081799  94 APPGTYPGPTAPAYPGPTAPGTQPGQPSGPGAYPPPGQPSAPGAYPAAGPFGIPAGPLTVPYDLPLPGGVKP 165
Cdd:PRK07764 698 PAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAA 769
PHA03378 PHA03378
EBNA-3B; Provisional
 16-178 6.83e-08

EBNA-3B; Provisional


Pssm-ID: 223065 [Multi-domain]  Cd Length: 991  Bit Score: 53.53  E-value: 6.83e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799  16 NPNPQGWPGPWGNQPAGAGGYPGASYPG-AYPGQAPPGgyPGQAPPGGYPGQAPPGGYPGQA-PPGGYPGQA-PPGGYPG 92
Cdd:PHA03378 675 QPSPTGANTMLPIQWAPGTMQPPPRAPTpMRPPAAPPG--RAQRPAAATGRARPPAAAPGRArPPAAAPGRArPPAAAPG 752

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799  93 QA-PPGTYPGPTAPAYPGPTAPGTQPGQPSGPGAYPPPGQPSAPGAYPAAGPFGIPAGPLTVPYDLPLPGGVKPRMLITI 171
Cdd:PHA03378 753 RArPPAAAPGRARPPAAAPGAPTPQPPPQAPPAPQQRPRGAPTPQPPPQAGPTSMQLMPRAAPGQQGPTKQILRQLLTGG 832


                 ....*..
gi 308081799 172 LGTVRPS 178
Cdd:PHA03378 833 VKRGRPS 839
PRK14959 PRK14959
DNA polymerase III subunits gamma and tau; Provisional
 47-148 1.50e-07

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184923 [Multi-domain]  Cd Length: 624  Bit Score: 52.37  E-value: 1.50e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799  47 GQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGTYPGPTAP---AYPGPTAPGTQP-GQPSG 122
Cdd:PRK14959 377 GASAPSGSAAEGPASGGAATIPTPGTQGPQGTAPAAGMTPSSAAPATPAPSAAPSPRVPwddAPPAPPRSGIPPrPAPRM 456

                         90       100       110
                 ....*....|....*....|....*....|
gi 308081799 123 PGAYPPPGQP----SAPGAYPAAGPFGIPA 148
Cdd:PRK14959 457 PEASPVPGAPdsvaSASDAPPTLGDPSDTA 486
PHA03247 PHA03247
large tegument protein UL36; Provisional
 17-183 5.73e-07

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 50.71  E-value: 5.73e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799   17 PNPQGWPGPWGNQPAGAGGYPGASYPGAYPGQAPPGGYPGQAPPGGYPGQA-PPGGYPGQAPPGGYPGQAP-PGGYPGQA 94
Cdd:PHA03247 2714 ALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAgPPAPAPPAAPAAGPPRRLTrPAVASLSE 2793

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799   95 PPGTYPGPTAPAYPGPTAPGTQPGQPsgPGAYPPPGQPSAPGAYPAAGPfgIPAGPltVPYDLPLPGGVKPRMLITILGT 174
Cdd:PHA03247 2794 SRESLPSPWDPADPPAAVLAPAAALP--PAASPAGPLPPPTSAQPTAPP--PPPGP--PPPSLPLGGSVAPGGDVRRRPP 2867


                  ....*....
gi 308081799  175 VRPSANRLA 183
Cdd:PHA03247 2868 SRSPAAKPA 2876
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 12-160 6.56e-07

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 50.37  E-value: 6.56e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799  12 SGSGNPNPQGWPGPWGNQPAGAGGYPGASYPGAYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGYP 91
Cdd:PRK07764 634 AAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQ 713

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 308081799  92 GQAPPGTYPGPTAPAypGPTAPGTQPGQPSGPGAYPPPGQPSAPGAYPAAGPFGIPAGPLTVPYDLPLP 160
Cdd:PRK07764 714 ADDPAAQPPQAAQGA--SAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPS 780
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 44-162 1.42e-06

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 49.21  E-value: 1.42e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799  44 AYPGQAPPGGYPGQAPPGGYPGQAPPGGYP-GQAPPGGYPGQAPPGGYPGQAPPGTYPGPTAPAYPGPTAPGTQPGQPSG 122
Cdd:PRK07764 586 AVVGPAPGAAGGEGPPAPASSGPPEEAARPaAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDG 665

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 308081799 123 PGAYPPPGQPSAPGAYPAAGPFGIPAGPLTVPYDLPLPGG 162
Cdd:PRK07764 666 GDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAP 705
dnaA PRK14086
chromosomal replication initiator protein DnaA;
9-161 1.56e-06

chromosomal replication initiator protein DnaA;


Pssm-ID: 237605 [Multi-domain]  Cd Length: 617  Bit Score: 49.05  E-value: 1.56e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799   9 DALSGSGNPNPQGWPGPWGNQPAGAGGYPGasYPGAYPgQAPPGGYPGqaPPGGYPGQAPPGGYPGQAPPGGyPGQAPPG 88
Cdd:PRK14086 116 RPYEGYGGPRADDRPPGLPRQDQLPTARPA--YPAYQQ-RPEPGAWPR--AADDYGWQQQRLGFPPRAPYAS-PASYAPE 189

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 308081799  89 GYPGQAPPGTYPGPTAPAYPGPTAPG---TQPGQPSGPGAYPPPGQPSAP-GAYPAAGPFGIPAGPLTVPYDLPLPG 161
Cdd:PRK14086 190 QERDREPYDAGRPEYDQRRRDYDHPRpdwDRPRRDRTDRPEPPPGAGHVHrGGPGPPERDDAPVVPIRPSAPGPLAA 266
dnaA PRK14086
chromosomal replication initiator protein DnaA;
17-154 1.63e-06

chromosomal replication initiator protein DnaA;


Pssm-ID: 237605 [Multi-domain]  Cd Length: 617  Bit Score: 49.05  E-value: 1.63e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799  17 PNPQGWPgPWGNQPAGAGGYPG---ASYPGAYPGqaPPGGYPGQAPPGGYPGQAPPGG----YPGQAPPGGYPGQAPP-- 87
Cdd:PRK14086 128 DRPPGLP-RQDQLPTARPAYPAyqqRPEPGAWPR--AADDYGWQQQRLGFPPRAPYASpasyAPEQERDREPYDAGRPey 204

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 308081799  88 ----GGYPGQAPPGTYPGPTAPAYPGPtAPGTQPGQPSGPGAYPPPGQPSAPGAYPAAGPFGIPAGPLTVP 154
Cdd:PRK14086 205 dqrrRDYDHPRPDWDRPRRDRTDRPEP-PPGAGHVHRGGPGPPERDDAPVVPIRPSAPGPLAAQPAPAPGP 274
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 10-143 1.94e-06

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 48.83  E-value: 1.94e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799  10 ALSGSGNPNPQGWPGPWGNQPAGAGGYPGASYPGAYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGG 89
Cdd:PRK07764 663 SDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLP 742

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 308081799  90 YPGQAPPGTYPGPTAPAYPGPTAPGTQPGQPSGPGAyPPPGQPSAPGAYPAAGP 143
Cdd:PRK07764 743 PEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSP-PSEEEEMAEDDAPSMDD 795
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 11-141 2.12e-06

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 48.83  E-value: 2.12e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799  11 LSGSGNPNPQGWPGPWGNQPAGAGGYPGASYPGAYPGQAPPGGYPGQAPPGGyPGQAPPggyPGQAPPGGYPGQAPPGGY 90
Cdd:PRK07764 385 LGVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPA-PAPAPP---SPAGNAPAGGAPSPPPAA 460

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 308081799  91 PGQAPPGtyPGPTAPAYPGPTAPGTQPGQPSGPGAYPPPGQPSAPGAYPAA 141
Cdd:PRK07764 461 APSAQPA--PAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPAGADDA 509
Glutenin_hmw pfam03157
High molecular weight glutenin subunit; Members of this family include high molecular weight ...
 29-135 2.37e-06

High molecular weight glutenin subunit; Members of this family include high molecular weight subunits of glutenin. This group of gluten proteins is thought to be largely responsible for the elastic properties of gluten, and hence, doughs. Indeed, glutenin high molecular weight subunits are classified as elastomeric proteins, because the glutenin network can withstand significant deformations without breaking, and return to the original conformation when the stress is removed. Elastomeric proteins differ considerably in amino acid sequence, but they are all polymers whose subunits consist of elastomeric domains, composed of repeated motifs, and non-elastic domains that mediate cross-linking between the subunits. The elastomeric domain motifs are all rich in glycine residues in addition to other hydrophobic residues. High molecular weight glutenin subunits have an extensive central elastomeric domain, flanked by two terminal non-elastic domains that form disulphide cross-links. The central elastomeric domain is characterized by the following three repeated motifs: PGQGQQ, GYYPTS[P/L]QQ, GQQ. It possesses overlapping beta-turns within and between the repeated motifs, and assumes a regular helical secondary structure with a diameter of approx. 1.9 nm and a pitch of approx. 1.5 nm.


Pssm-ID: 367362 [Multi-domain]  Cd Length: 786  Bit Score: 48.79  E-value: 2.37e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799   29 QPAGAGGYPGASYPGA--YPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGTYpgPTAPA 106
Cdd:pfam03157 441 QQPGQGQQPGQEQPGQgqQPGQGQQGQQPGQPEQGQQPGQGQPGYYPTSPQQSGQGQQLGQWQQQGQGQPGYY--PTSPL 518

                          90       100
                  ....*....|....*....|....*....
gi 308081799  107 YPGPTAPGTQPGQPSGPGAYPPPGQPSAP 135
Cdd:pfam03157 519 QPGQGQPGYYPTSPQQPGQGQQLGQLQQP 547
PRK14959 PRK14959
DNA polymerase III subunits gamma and tau; Provisional
 29-143 2.58e-06

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184923 [Multi-domain]  Cd Length: 624  Bit Score: 48.52  E-value: 2.58e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799  29 QPAGAGGYPgasyPGAYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGYPG------QAPPgTYPGP 102
Cdd:PRK14959 372 RPSGGGASA----PSGSAAEGPASGGAATIPTPGTQGPQGTAPAAGMTPSSAAPATPAPSAAPSprvpwdDAPP-APPRS 446

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 308081799 103 TAPAYPGPTAPGTQP--GQP----SGPGAYPPPGQPSAPGAYPAAGP 143
Cdd:PRK14959 447 GIPPRPAPRMPEASPvpGAPdsvaSASDAPPTLGDPSDTAEHTPSGP 493
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
12-166 4.31e-06

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 47.95  E-value: 4.31e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799  12 SGSGNPNPQGWPGPWGNQPAGAGGYPGASYPGAYPGQAPPGGYPGQAPPGGYPG--------QAPPGGYPGQAPPGGYPG 83
Cdd:PRK12323 376 TAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPApealaaarQASARGPGGAPAPAPAPA 455

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799  84 QAPPGGYPGQAPPGTYPGPTAPAYPGPTAPGTQPgqpsGPGAYPPPGQPSAPGAYPAAGPFGIPAGPL-TVPYDLPLPGG 162
Cdd:PRK12323 456 AAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAP----APADDDPPPWEELPPEFASPAPAQPDAAPAgWVAESIPDPAT 531


                 ....
gi 308081799 163 VKPR 166
Cdd:PRK12323 532 ADPD 535
PHA03247 PHA03247
large tegument protein UL36; Provisional
 29-179 5.11e-06

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 48.01  E-value: 5.11e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799   29 QPAGAGGYP-GASYPGAYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGyPGQAPPGGYPGQAPPGTYPGPTAPAY 107
Cdd:PHA03247 2672 RAAQASSPPqRPRRRAARPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPG-PAAARQASPALPAAPAPPAVPAGPAT 2750

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 308081799  108 PGPTAPGTQPGQPSGPGAYPPPGQPSAPGA----YPAAGPFGIPAGPLTVPYDLPLPGGVKPRMLITILGTVRPSA 179
Cdd:PHA03247 2751 PGGPARPARPPTTAGPPAPAPPAAPAAGPPrrltRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAG 2826
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 15-150 8.24e-06

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 46.82  E-value: 8.24e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799  15 GNPNPQGWPGPWGnqPAGAGGYPGASYPGAYPGQAPPG--GYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGYPG 92
Cdd:NF038329 198 GETGPAGEQGPAG--PAGPDGEAGPAGEDGPAGPAGDGqqGPDGDPGPTGEDGPQGPDGPAGKDGPRGDRGEAGPDGPDG 275

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 308081799  93 QAPPGTYPGPTAP-------AYPGPTAPGTQPGQPSGPGAYPPPGQPSAPGAYPAAGPFGIPAGP 150
Cdd:NF038329 276 KDGERGPVGPAGKdgqngkdGLPGKDGKDGQNGKDGLPGKDGKDGQPGKDGLPGKDGKDGQPGKP 340
Chi1 COG3469
Chitinase [Carbohydrate transport and metabolism];
12-163 8.41e-06

Chitinase [Carbohydrate transport and metabolism];


Pssm-ID: 442692 [Multi-domain]  Cd Length: 534  Bit Score: 46.67  E-value: 8.41e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799  12 SGSGNPNPQGWPGPWGNQPAGAGGYPGASYPGAYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGYP 91
Cdd:COG3469   65 AASSTAATSSTTSTTATATAAAAAATSTSATLVATSTASGANTGTSTVTTTSTGAGSVTSTTSSTAGSTTTSGASATSSA 144

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 308081799  92 GQAPPGTYPGPTAPAYPGPTAPGTQPGQPSGPGAYPPPGQPSAPGAYPAAGPFGIPAGPLTVPYDLPLPGGV 163
Cdd:COG3469  145 GSTTTTTTVSGTETATGGTTTTSTTTTTTSASTTPSATTTATATTASGATTPSATTTATTTGPPTPGLPKHV 216
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
13-150 8.51e-06

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 46.79  E-value: 8.51e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799  13 GSGNPNPQGWPGPWGNQPAGAGGYPG-ASYPGAYPGQAPPGGYPGQAPPGGYPGQAP----PGGYPGQAPPGGYPGQAPP 87
Cdd:PRK12323 424 ARRSPAPEALAAARQASARGPGGAPApAPAPAAAPAAAARPAAAGPRPVAAAAAAAParaaPAAAPAPADDDPPPWEELP 503

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 308081799  88 GGYPGQAPPGTYPGPTAPAYPGPTAPGTQPGQPSGPGAYPPPGQPSAPGAYPAAGPFGIPAGP 150
Cdd:PRK12323 504 PEFASPAPAQPDAAPAGWVAESIPDPATADPDDAFETLAPAPAAAPAPRAAAATEPVVAPRPP 566
kgd PRK12270
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ...
 73-154 1.25e-05

multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;


Pssm-ID: 237030 [Multi-domain]  Cd Length: 1228  Bit Score: 46.42  E-value: 1.25e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799   73 PGQAPPGGYPGQAPPGGYPGQAPPGTYPGPTAPAYPGPTAPGTQPGQPSGPGAYPPPGQPSAPGAYPAAGPFGIPAGPLT 152
Cdd:PRK12270   38 PGSTAAPTAAAAAAAAAASAPAAAPAAKAPAAPAPAPPAAAAPAAPPKPAAAAAAAAAPAAPPAAAAAAAPAAAAVEDEV 117


                  ..
gi 308081799  153 VP 154
Cdd:PRK12270  118 TP 119
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 30-157 1.46e-05

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 46.25  E-value: 1.46e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799  30 PAGAGGYPG--ASYPGAYPGQAPPGGYP-GQAPPGGYPGQAPPGGYPGQAPPggyPGQAPPGgyPGQAPPGTYPGPTAPA 106
Cdd:PRK14951 366 PAAAAEAAApaEKKTPARPEAAAPAAAPvAQAAAAPAPAAAPAAAASAPAAP---PAAAPPA--PVAAPAAAAPAAAPAA 440

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 308081799 107 YPGPTAPGTQPGQPSGP--GAYPPPGQPSAPGAYPAAGPFGIPAGPLTVPYDL 157
Cdd:PRK14951 441 APAAVALAPAPPAQAAPetVAIPVRVAPEPAVASAAPAPAAAPAAARLTPTEE 493
Atrophin-1 pfam03154
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ...
 46-165 2.39e-05

Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.


Pssm-ID: 460830 [Multi-domain]  Cd Length: 991  Bit Score: 45.53  E-value: 2.39e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799   46 PGQAPPGGYPGQA-PPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGYP-------GQAPPGTYPGPTAPAYPGPTAPGTQP 117
Cdd:pfam03154 253 TQPPPPSQVSPQPlPQPSLHGQMPPMPHSLQTGPSHMQHPVPPQPFPltpqssqSQVPPGPSPAAPGQSQQRIHTPPSQS 332

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 308081799  118 GQPSG---------------PGAYPPPGQPSAPGAYPAAG---PFGIPAGPLTVPYDLPLPGGVKP 165
Cdd:pfam03154 333 QLQSQqppreqplppaplsmPHIKPPPTTPIPQLPNPQSHkhpPHLSGPSPFQMNSNLPPPPALKP 398
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 15-150 4.57e-05

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 44.51  E-value: 4.57e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799  15 GNPNPQGWPGPWGNQ----PAGAGGYPGASYPGAYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGY 90
Cdd:NF038329 126 GPAGPAGEQGPRGDRgetgPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGEAGAKGPAGEKGPQGPRGETGPAGE 205

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 308081799  91 P-GQAPPG--------TYPGPTAPAYPGPTAPGTQPGQPSGPGAYPPPGQPSAPGAYPAAGPFGiPAGP 150
Cdd:NF038329 206 QgPAGPAGpdgeagpaGEDGPAGPAGDGQQGPDGDPGPTGEDGPQGPDGPAGKDGPRGDRGEAG-PDGP 273
PHA03264 PHA03264
envelope glycoprotein D; Provisional
 43-149 4.79e-05

envelope glycoprotein D; Provisional


Pssm-ID: 223029 [Multi-domain]  Cd Length: 416  Bit Score: 44.23  E-value: 4.79e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799  43 GAYPGQAPPGGYPgqAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGTYPGPTAPAYPGPTAPGTQP-GQPS 121
Cdd:PHA03264 263 GYEPPPAPSGGSP--APPGDDRPEAKPEPGPVEDGAPGRETGGEGEGPEPAGRDGAAGGEPKPGPPRPAPDADRPeGWPS 340

                         90       100
                 ....*....|....*....|....*...
gi 308081799 122 GPGAYPPPGQPSAPGAyPAAGPFGIPAG 149
Cdd:PHA03264 341 LEAITFPPPTPATPAV-PRARPVIVGTG 367
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 37-175 6.43e-05

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 44.32  E-value: 6.43e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799  37 PGASYPGAYPGQAPPGGYPGQAPPGGYPgqappggyPGQAPPGGYPGQAPPGGYPGQAPPGTYPGPtAPAYPGPTAPGTQ 116
Cdd:PRK14951 366 PAAAAEAAAPAEKKTPARPEAAAPAAAP--------VAQAAAAPAPAAAPAAAASAPAAPPAAAPP-APVAAPAAAAPAA 436

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799 117 PGQPSGPGAYPPPGQPSAPGAYPAAGPFGIPAGP-LTVPYDLPLPGGVKPRMLITILGTV 175
Cdd:PRK14951 437 APAAAPAAVALAPAPPAQAAPETVAIPVRVAPEPaVASAAPAPAAAPAAARLTPTEEGDV 496
dnaA PRK14086
chromosomal replication initiator protein DnaA;
19-134 7.50e-05

chromosomal replication initiator protein DnaA;


Pssm-ID: 237605 [Multi-domain]  Cd Length: 617  Bit Score: 44.05  E-value: 7.50e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799  19 PQGWPGPWGNQPAGAGG-YPGASYPGAYPGQAPPGGYPGQA----PPG------GYPGQAPPGGYPGQAPPGGY----PG 83
Cdd:PRK14086 151 QRPEPGAWPRAADDYGWqQQRLGFPPRAPYASPASYAPEQErdrePYDagrpeyDQRRRDYDHPRPDWDRPRRDrtdrPE 230

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 308081799  84 QAPPGGYPGQAPPGTYPGPTAPAYP-GPTAPGTQPGQPSgpgAYPPPGQPSA 134
Cdd:PRK14086 231 PPPGAGHVHRGGPGPPERDDAPVVPiRPSAPGPLAAQPA---PAPGPGEPTA 279
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
10-164 1.33e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 43.30  E-value: 1.33e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799  10 ALSGSGNPNPQGWPGPWGNQPAGAGGYPGASYPGAYPGQAPPGGYPGQA--PPGGYPGQAPPGGYPGQAPPGGYPGQAPP 87
Cdd:PRK07003 361 AVTGGGAPGGGVPARVAGAVPAPGARAAAAVGASAVPAVTAVTGAAGAAlaPKAAAAAAATRAEAPPAAPAPPATADRGD 440

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 308081799  88 GGYPGQAPPGTYPGPTAPAYPGPTAPGTQPGQPSGPGAYPPPGQPSAPGAYPAAGPFGIPAGPLTVPYDLPLPGGVK 164
Cdd:PRK07003 441 DAADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAAAS 517
PHA03247 PHA03247
large tegument protein UL36; Provisional
 42-166 1.46e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 43.39  E-value: 1.46e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799   42 PGAYPGQAPPGGYPGQAPPGGYPGQAP-------PGGYPGQAPPGGYPGQAPPGG---------YPGQAPPGTYP--GPT 103
Cdd:PHA03247 2605 RGDPRGPAPPSPLPPDTHAPDPPPPSPspaanepDPHPPPTVPPPERPRDDPAPGrvsrprrarRLGRAAQASSPpqRPR 2684

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 308081799  104 APAYPGPTAPGTQPGQPSGPGAYPPPGQPSAPGAYP-----AAGPFGIPAGPLT-----VPYDLPLPGGVKPR 166
Cdd:PHA03247 2685 RRAARPTVGSLTSLADPPPPPPTPEPAPHALVSATPlppgpAAARQASPALPAApappaVPAGPATPGGPARP 2757
kgd PRK12270
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ...
 55-145 1.72e-04

multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;


Pssm-ID: 237030 [Multi-domain]  Cd Length: 1228  Bit Score: 42.96  E-value: 1.72e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799   55 PGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGTYPGPTAPAYPGPTAPgtqPGQPSGPGAYPPPGQPSA 134
Cdd:PRK12270   38 PGSTAAPTAAAAAAAAAASAPAAAPAAKAPAAPAPAPPAAAAPAAPPKPAAAAAAAAAP---AAPPAAAAAAAPAAAAVE 114

                          90
                  ....*....|.
gi 308081799  135 PGAYPAAGPFG 145
Cdd:PRK12270  115 DEVTPLRGAAA 125
PHA03378 PHA03378
EBNA-3B; Provisional
 18-154 2.14e-04

EBNA-3B; Provisional


Pssm-ID: 223065 [Multi-domain]  Cd Length: 991  Bit Score: 42.75  E-value: 2.14e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799  18 NPQGWPGP-WGNQPAGAGGYPGASYPGAYPGQAPPGGYPGQAPPGGYPGQAPPggyPGQAPPGGYPGQAPPGgyPGQAPP 96
Cdd:PHA03378 644 NVLVFPTPhQPPQVEITPYKPTWTQIGHIPYQPSPTGANTMLPIQWAPGTMQP---PPRAPTPMRPPAAPPG--RAQRPA 718

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799  97 G-TYPGPTAPAYPGPT-APGTQPGQPSGPGAYPPPGQPSAPGAYPAAGPFGIPAGPLTVP 154
Cdd:PHA03378 719 AaTGRARPPAAAPGRArPPAAAPGRARPPAAAPGRARPPAAAPGRARPPAAAPGAPTPQP 778
PHA03247 PHA03247
large tegument protein UL36; Provisional
 15-166 2.37e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 42.62  E-value: 2.37e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799   15 GNPNPQGWPGPWGNQPAGAGGYPGASYPGAYPGQAPP------------------GGYPGQAPPggypgqAPPGGYPGQA 76
Cdd:PHA03247 2494 AAPDPGGGGPPDPDAPPAPSRLAPAILPDEPVGEPVHprmltwirgleelasddaGDPPPPLPP------AAPPAAPDRS 2567

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799   77 PPGGYPGQAPPGGYPG--QAPPGTYPGPTAPAYPG-PTAPGTQPGQPSGPGAYPPPGQPSAPGAYPAA----GPFGIPAG 149
Cdd:PHA03247 2568 VPPPRPAPRPSEPAVTsrARRPDAPPQSARPRAPVdDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAAnepdPHPPPTVP 2647

                         170
                  ....*....|....*..
gi 308081799  150 PLTVPYDLPLPGGVKPR 166
Cdd:PHA03247 2648 PPERPRDDPAPGRVSRP 2664
PHA03247 PHA03247
large tegument protein UL36; Provisional
 17-150 3.65e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 42.23  E-value: 3.65e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799   17 PNPQGWPgpwgnQPAGAGGYPGASYPGAYPGQA-------PPGGYPGQAPPGGYPGQAPPggyPGQAPPGGYP-GQAPPG 88
Cdd:PHA03247 2569 PPPRPAP-----RPSEPAVTSRARRPDAPPQSArprapvdDRGDPRGPAPPSPLPPDTHA---PDPPPPSPSPaANEPDP 2640

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 308081799   89 GYPGQAPPGTYPgPTAPAYPGPTAPGTQPGQPSGPGAYPPPGQPSAPGAYPAAGPFGIPAGP 150
Cdd:PHA03247 2641 HPPPTVPPPERP-RDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADP 2701
PHA03378 PHA03378
EBNA-3B; Provisional
 16-162 3.80e-04

EBNA-3B; Provisional


Pssm-ID: 223065 [Multi-domain]  Cd Length: 991  Bit Score: 41.98  E-value: 3.80e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799  16 NPNPQGWPGPWGNQPAGAGGYPGASYpgAYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQA- 94
Cdd:PHA03378 618 TSAPRQWPMPLRPIPMRPLRMQPITF--NVLVFPTPHQPPQVEITPYKPTWTQIGHIPYQPSPTGANTMLPIQWAPGTMq 695

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 308081799  95 PPGTYPGPTAPAYPGPTA---PGTQPGQPSGPGAYPPPGQPSAPGAYPAAGPFGIPAG---PLTVPYDLPLPGG 162
Cdd:PHA03378 696 PPPRAPTPMRPPAAPPGRaqrPAAATGRARPPAAAPGRARPPAAAPGRARPPAAAPGRarpPAAAPGRARPPAA 769
PRK14965 PRK14965
DNA polymerase III subunits gamma and tau; Provisional
 79-205 5.04e-04

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237871 [Multi-domain]  Cd Length: 576  Bit Score: 41.27  E-value: 5.04e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799  79 GGYPGQAPPGGYPGQAPPGTYPGPTAPAYPGPTAPGTQPGQPSGPGAYPPPGQPSAPGAYPAAGPFGIPAGPLTVPYDLp 158
Cdd:PRK14965 380 GAPAPPSAAWGAPTPAAPAAPPPAAAPPVPPAAPARPAAARPAPAPAPPAAAAPPARSADPAAAASAGDRWRAFVAFVK- 458

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 308081799 159 lpgGVKPRmLITILGTVRP---SANRLALDFKRGndvAFHFNPRFNEDNK 205
Cdd:PRK14965 459 ---GKKPA-LGASLEQGSPlgvSAGLLEIGFPEG---SFELSAMQDPDSR 501
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
 30-125 6.04e-04

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 40.95  E-value: 6.04e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799  30 PAGAGGYPGASYPGAYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGT---YPGPTAPA 106
Cdd:PRK14950 364 PAPQPAKPTAAAPSPVRPTPAPSTRPKAAAAANIPPKEPVRETATPPPVPPRPVAPPVPHTPESAPKLTraaIPVDEKPK 443

                         90
                 ....*....|....*....
gi 308081799 107 YPGPTAPGTQPGQPSGPGA 125
Cdd:PRK14950 444 YTPPAPPKEEEKALIADGD 462
PABP-1234 TIGR01628
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins ...
 19-143 6.41e-04

polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins recognize the poly-A of mRNA and consists of four tandem RNA recognition domains at the N-terminus (rrm: pfam00076) followed by a PABP-specific domain (pfam00658) at the C-terminus. The protein is involved in the transport of mRNA's from the nucleus to the cytoplasm. There are four paralogs in Homo sapiens which are expressed in testis, platelets, broadly expressed and of unknown tissue range.


Pssm-ID: 130689 [Multi-domain]  Cd Length: 562  Bit Score: 40.95  E-value: 6.41e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799   19 PQGWPGPWGNQPAGAGGYPgasypgAYPGQAPPGGYPGQapPGGYPGQAPpggypgqAPPGGYPG-QAPPGGYPGQAPPG 97
Cdd:TIGR01628 380 PRMRQLPMGSPMGGAMGQP------PYYGQGPQQQFNGQ--PLGWPRMSM-------MPTPMGPGgPLRPNGLAPMNAVR 444

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 308081799   98 TyPGPTAPAYPGPTAPGTQPGQPSGPGAYPPPGQPSAPGAYPAAGP 143
Cdd:TIGR01628 445 A-PSRNAQNAAQKPPMQPVMYPPNYQSLPLSQDLPQPQSTASQGGQ 489
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 76-154 6.56e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 41.12  E-value: 6.56e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 308081799  76 APPGGYPGQAPPGGYPGQAPPGTYPGPTAPAYPGPTAPGTQPGQPSGPGAYPPPGQPSAPGAYPAAGPFGIPAGPLTVP 154
Cdd:PRK07764 388 AGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQP 466
SPT5 COG5164
Transcription elongation factor SPT5 [Transcription];
13-150 7.32e-04

Transcription elongation factor SPT5 [Transcription];


Pssm-ID: 444063 [Multi-domain]  Cd Length: 495  Bit Score: 40.78  E-value: 7.32e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799  13 GSGNPNPQGWPGPWGNQPAGAGGYPGASYPGAYPGQAPPGGYPGQAPPGgyPGQAPPGGYPGQAPPGGYPGQAPPGGYPG 92
Cdd:COG5164   98 GTTPAGDGGATGPPDDGGATGPPDDGGSTTPPSGGSTTPPGDGGSTPPG--PGSTGPGGSTTPPGDGGSTTPPGPGGSTT 175

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 308081799  93 QAPPGTYPGPTAPAYPGPTAPGTQPGQPSGPGAYPPPGQPSAPGAYPAAGPFGIPAGP 150
Cdd:COG5164  176 PPDDGGSTTPPNKGETGTDIPTGGTPRQGPDGPVKKDDKNGKGNPPDDRGGKTGPKDQ 233
Glutenin_hmw pfam03157
High molecular weight glutenin subunit; Members of this family include high molecular weight ...
 25-141 7.74e-04

High molecular weight glutenin subunit; Members of this family include high molecular weight subunits of glutenin. This group of gluten proteins is thought to be largely responsible for the elastic properties of gluten, and hence, doughs. Indeed, glutenin high molecular weight subunits are classified as elastomeric proteins, because the glutenin network can withstand significant deformations without breaking, and return to the original conformation when the stress is removed. Elastomeric proteins differ considerably in amino acid sequence, but they are all polymers whose subunits consist of elastomeric domains, composed of repeated motifs, and non-elastic domains that mediate cross-linking between the subunits. The elastomeric domain motifs are all rich in glycine residues in addition to other hydrophobic residues. High molecular weight glutenin subunits have an extensive central elastomeric domain, flanked by two terminal non-elastic domains that form disulphide cross-links. The central elastomeric domain is characterized by the following three repeated motifs: PGQGQQ, GYYPTS[P/L]QQ, GQQ. It possesses overlapping beta-turns within and between the repeated motifs, and assumes a regular helical secondary structure with a diameter of approx. 1.9 nm and a pitch of approx. 1.5 nm.


Pssm-ID: 367362 [Multi-domain]  Cd Length: 786  Bit Score: 41.09  E-value: 7.74e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799   25 PWGNQPAGAGGYPGASYPGAYPGQAPPGGYPGQAPPGG---YPGQAPPGGYPGQAPPGGYPGQappGGYPGQAPPGTYPG 101
Cdd:pfam03157 173 SGQRQQPGQGQQLRQGQQGQQSGQGQPGYYPTSSQQPGqlqQTGQGQQGQQPERGQQGQQPGQ---GQQPGQGQQGQQPG 249

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 308081799  102 ptAPAYPGPTAPGTQPGQPSGPGAYPPPGQpSAPGAYPAA 141
Cdd:pfam03157 250 --QPQQLGQGQQGYYPISPQQPRQWQQSGQ-GQQGYYPTS 286
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
29-154 8.38e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 40.60  E-value: 8.38e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799  29 QPAGAGG-YPGASYPGAYPGQAPPggyPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQ---APPGGYPGQAPPGTYPGPTA 104
Cdd:PRK07003 359 EPAVTGGgAPGGGVPARVAGAVPA---PGARAAAAVGASAVPAVTAVTGAAGAALAPkaaAAAAATRAEAPPAAPAPPAT 435

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 308081799 105 PAYPGPTAPGTQPGQPSGPGAYPPPGQPSAPGAYPAAGPFGIPAGPLTVP 154
Cdd:PRK07003 436 ADRGDDAADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAP 485
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
50-166 8.84e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 40.63  E-value: 8.84e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799  50 PPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGTYPGPTAPAYPGPTAPGTQPGQPSGPGAYPPP 129
Cdd:PRK12323 365 PGQSGGGAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGP 444

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 308081799 130 GQPSAPGAYPAAGPFGIPAGPLTVPYDLPLPGGVKPR 166
Cdd:PRK12323 445 GGAPAPAPAPAAAPAAAARPAAAGPRPVAAAAAAAPA 481
dnaA PRK14086
chromosomal replication initiator protein DnaA;
50-166 9.11e-04

chromosomal replication initiator protein DnaA;


Pssm-ID: 237605 [Multi-domain]  Cd Length: 617  Bit Score: 40.58  E-value: 9.11e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799  50 PPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGTYPG--PTAPAYPGPTAPGTQPGQPSGPG--- 124
Cdd:PRK14086  90 PSAGEPAPPPPHARRTSEPELPRPGRRPYEGYGGPRADDRPPGLPRQDQLPTarPAYPAYQQRPEPGAWPRAADDYGwqq 169

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 308081799 125 ---AYPPPGQPSAPGAY-PAAGPFGIPAGPLTVPYDLPLPGGVKPR 166
Cdd:PRK14086 170 qrlGFPPRAPYASPASYaPEQERDREPYDAGRPEYDQRRRDYDHPR 215
MISS pfam15822
MAPK-interacting and spindle-stabilising protein-like; MISS is a family of eukaryotic ...
 19-165 9.23e-04

MAPK-interacting and spindle-stabilising protein-like; MISS is a family of eukaryotic MAPK-interacting and spindle-stabilising protein-like proteins. MISS is rich in prolines and has four potential MAPK-phosphorylation sites, a MAPK-docking site, a PEST sequence (PEST motif) and a bipartite nuclear localization signal. The endogenous protein accumulates during mouse meiotic maturation and is found as discrete dots on the MII spindle. MISS is the first example of a physiological MAPK-substrate that is stabilized in MII that specifically regulates MII spindle integrity during the CSF arrest.


Pssm-ID: 318115 [Multi-domain]  Cd Length: 238  Bit Score: 39.97  E-value: 9.23e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799   19 PQGWPG--PWGN---QPAGAGGYPGASYPGAYP-GQAPPGGYPGQAPPGGYPGQAPP------------GGYPGQAPPG- 79
Cdd:pfam15822  27 PQGWPGsnPWNNpsaPPAVPSGLPPSTAPSTVPfGPAPTGMYPSIPLTGPSPGPPAPfppsgpscpppgGPYPAPTVPGp 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799   80 GYPGQAPPGGYPGQAPPGTYPGPTAPAYPGPTAP-GTQPGQPSGP---GAYPPPGQP-SAPGAYPAAGPFGIPAGPLTVP 154
Cdd:pfam15822 107 GPIGPYPTPNMPFPELPRPYGAPTDPAAAAPSGPwGSMSSGPWAPgmgGQYPAPNMPyPSPGPYPAVPPPQSPGAAPPVP 186

                         170
                  ....*....|.
gi 308081799  155 YDLPLPGGVKP 165
Cdd:pfam15822 187 WGTVPPGPWGP 197
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 69-165 9.60e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 40.74  E-value: 9.60e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799  69 PGGYPGQAPPGGYPGQAPPGGYPGQAPPGTYPGPTAPAYPgptAPGTQPGQPSGPGAYPPPGQPSAPGAYPAAGPFGIPA 148
Cdd:PRK07764 588 VGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAP---APAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASD 664

                         90
                 ....*....|....*..
gi 308081799 149 GPLTVPYDLPLPGGVKP 165
Cdd:PRK07764 665 GGDGWPAKAGGAAPAAP 681
PHA03378 PHA03378
EBNA-3B; Provisional
 17-179 9.77e-04

EBNA-3B; Provisional


Pssm-ID: 223065 [Multi-domain]  Cd Length: 991  Bit Score: 40.44  E-value: 9.77e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799  17 PNPQGWPGPwGNQPAGAGGypGASYPGAYPGQA-PPGGYPGQA-PPGGYPGQAPPGGYPgQAPPGgyPGQAPPGGYPGQA 94
Cdd:PHA03378 725 RPPAAAPGR-ARPPAAAPG--RARPPAAAPGRArPPAAAPGRArPPAAAPGAPTPQPPP-QAPPA--PQQRPRGAPTPQP 798

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799  95 PPGTYPGP---TAPAYPGPTAPGTQPGQPSGPGAY----PPPGQPSAPGAYPAAGPFGIPAGPL---TVPYDLPLPGGVK 164
Cdd:PHA03378 799 PPQAGPTSmqlMPRAAPGQQGPTKQILRQLLTGGVkrgrPSLKKPAALERQAAAGPTPSPGSGTsdkIVQAPVFYPPVLQ 878

                        170
                 ....*....|....*
gi 308081799 165 PRMLITILGTVRPSA 179
Cdd:PHA03378 879 PIQVMRQLGSVRAAA 893
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
30-140 1.07e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 40.24  E-value: 1.07e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799  30 PAGAGGYPGASYPGAYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGTYPGPTAPAYPG 109
Cdd:PRK12323 473 AAAAAAAPARAAPAAAPAPADDDPPPWEELPPEFASPAPAQPDAAPAGWVAESIPDPATADPDDAFETLAPAPAAAPAPR 552

                         90       100       110
                 ....*....|....*....|....*....|.
gi 308081799 110 PTAPGTQPGQPSGPGAYPPPGQPSAPGAYPA 140
Cdd:PRK12323 553 AAAATEPVVAPRPPRASASGLPDMFDGDWPA 583
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 23-124 1.12e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 40.35  E-value: 1.12e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799  23 PGPWGNQPAGAGGYPGASYPGAYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGTYPGP 102
Cdd:PRK07764 410 PAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPA 489

                         90       100
                 ....*....|....*....|..
gi 308081799 103 TAPAYPGPTAPGTQPGQPSGPG 124
Cdd:PRK07764 490 PAAAPAAPAAPAAPAGADDAAT 511
PRK14965 PRK14965
DNA polymerase III subunits gamma and tau; Provisional
 49-157 1.12e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237871 [Multi-domain]  Cd Length: 576  Bit Score: 40.11  E-value: 1.12e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799  49 APPGGYPGQAPPGGYPGQAPPggyPGQAPPGGYPGQAPPGgypgQAPPGtyPGPTAPAYPGPTAPGTQPGQPSGPGAYPP 128
Cdd:PRK14965 381 APAPPSAAWGAPTPAAPAAPP---PAAAPPVPPAAPARPA----AARPA--PAPAPPAAAAPPARSADPAAAASAGDRWR 451

                         90       100
                 ....*....|....*....|....*....
gi 308081799 129 PGQPSAPGAYPAAGPFGIPAGPLTVPYDL 157
Cdd:PRK14965 452 AFVAFVKGKKPALGASLEQGSPLGVSAGL 480
PRK14965 PRK14965
DNA polymerase III subunits gamma and tau; Provisional
 38-114 1.18e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237871 [Multi-domain]  Cd Length: 576  Bit Score: 40.11  E-value: 1.18e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 308081799  38 GASYPGAYPGQAPPGGYPGQAPPGGypgqAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGTYPGPTAPAYPGPTAPG 114
Cdd:PRK14965 380 GAPAPPSAAWGAPTPAAPAAPPPAA----APPVPPAAPARPAAARPAPAPAPPAAAAPPARSADPAAAASAGDRWRA 452
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
8-112 1.51e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 39.76  E-value: 1.51e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799   8 NDALSGSGNPNPQGWPGPWGNQPAGAGGYPGASYPGAYPGQAPPGGYPGQAPPGGYPGQAPPggyPGQAPPGGyPGQAPP 87
Cdd:PRK14971 364 QKGDDASGGRGPKQHIKPVFTQPAAAPQPSAAAAASPSPSQSSAAAQPSAPQSATQPAGTPP---TVSVDPPA-AVPVNP 439

                         90       100
                 ....*....|....*....|....*
gi 308081799  88 ggyPGQAPPGTYPGPTAPAYPGPTA 112
Cdd:PRK14971 440 ---PSTAPQAVRPAQFKEEKKIPVS 461
PHA03247 PHA03247
large tegument protein UL36; Provisional
 42-179 1.57e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 39.92  E-value: 1.57e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799   42 PGAYPGQAPPGGYPGQAPPGG--YPGQAPPGGYPGQAPPGGYPGQAPPGGypgQAPPGTYPGPTAPayPGPTAPGTQPGQ 119
Cdd:PHA03247 2704 PPPTPEPAPHALVSATPLPPGpaAARQASPALPAAPAPPAVPAGPATPGG---PARPARPPTTAGP--PAPAPPAAPAAG 2778

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 308081799  120 PSgPGAYPPPGQPSAPGAYPAAGPFGIPAGPLTVPYDLP-LPGGVKPRMLITILGTVRPSA 179
Cdd:PHA03247 2779 PP-RRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAaLPPAASPAGPLPPPTSAQPTA 2838
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 23-143 1.58e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 40.15  E-value: 1.58e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799   23 PGPWGNQPAGAGGYPGASYPGAYPGQAPPGGYPGQAPPGGYPGQappggyPGQAPPGGYPGQAPPGGYPGQAPPGTYPGP 102
Cdd:PHA03307   65 FEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTP------PGPSSPDPPPPTPPPASPPPSPAPDLSEML 138

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 308081799  103 TAPAYPGPTAPGTQPGQPSGPGAYPPPGQPSAPGAYPAAGP 143
Cdd:PHA03307  139 RPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSP 179
PHA03247 PHA03247
large tegument protein UL36; Provisional
 14-160 1.60e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 39.92  E-value: 1.60e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799   14 SGNPNPQGWPGPWGNQPAGAGGYPGAsyPGAYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGypGQAPPGGYPGQ 93
Cdd:PHA03247 2790 SLSESRESLPSPWDPADPPAAVLAPA--AALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGG--SVAPGGDVRRR 2865

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 308081799   94 APPGTYPG-PTAPAYP------GPTAPGTQPGQPSGPGAYPPPGQPSAPGAYPAAGPFGIPAGPLTVPYDLPLP 160
Cdd:PHA03247 2866 PPSRSPAAkPAAPARPpvrrlaRPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRP 2939
Glutenin_hmw pfam03157
High molecular weight glutenin subunit; Members of this family include high molecular weight ...
 25-136 1.89e-03

High molecular weight glutenin subunit; Members of this family include high molecular weight subunits of glutenin. This group of gluten proteins is thought to be largely responsible for the elastic properties of gluten, and hence, doughs. Indeed, glutenin high molecular weight subunits are classified as elastomeric proteins, because the glutenin network can withstand significant deformations without breaking, and return to the original conformation when the stress is removed. Elastomeric proteins differ considerably in amino acid sequence, but they are all polymers whose subunits consist of elastomeric domains, composed of repeated motifs, and non-elastic domains that mediate cross-linking between the subunits. The elastomeric domain motifs are all rich in glycine residues in addition to other hydrophobic residues. High molecular weight glutenin subunits have an extensive central elastomeric domain, flanked by two terminal non-elastic domains that form disulphide cross-links. The central elastomeric domain is characterized by the following three repeated motifs: PGQGQQ, GYYPTS[P/L]QQ, GQQ. It possesses overlapping beta-turns within and between the repeated motifs, and assumes a regular helical secondary structure with a diameter of approx. 1.9 nm and a pitch of approx. 1.5 nm.


Pssm-ID: 367362 [Multi-domain]  Cd Length: 786  Bit Score: 39.55  E-value: 1.89e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799   25 PWGNQPAGAGGYPGASYPGAYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQappGGYPGQAPPGGYP------------- 91
Cdd:pfam03157 535 PGQGQQLGQLQQPTQGQQGQQSGQGQQGQQPGQGQQGQQPGQGQQGQQPGQ---GQQPGQGQPGYYPtspqqsgqgqqpg 611

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 308081799   92 -----GQAPPGTYpgPTAPAYPGPTAPGTQPGQPSGPGAYPPPGQPSAPG 136
Cdd:pfam03157 612 qwqqpGQGQPGYY--PTSSLQLGQGQQGYYPTSPQQPGQGQQPGQWQQSG 659
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
56-179 2.14e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 39.45  E-value: 2.14e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799  56 GQAPPGGYPGQAPPG-GYPGQAPPGGYPGQAPPGGYPGQAPPGTYPGPTAPAYPGPTAPGTQPGQPSgPGAYPPPGQPSA 134
Cdd:PRK07003 365 GGAPGGGVPARVAGAvPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPA-PPATADRGDDAA 443

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 308081799 135 PGAYPAAGPFGIPAGPLTVPYDLPLPGGVKPRMLITILGTVRPSA 179
Cdd:PRK07003 444 DGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDA 488
Med15 pfam09606
ARC105 or Med15 subunit of Mediator complex non-fungal; The approx. 70 residue Med15 domain of ...
 27-143 2.17e-03

ARC105 or Med15 subunit of Mediator complex non-fungal; The approx. 70 residue Med15 domain of the ARC-Mediator co-activator is a three-helix bundle with marked similarity to the KIX domain. The sterol regulatory element binding protein (SREBP) family of transcription activators use the ARC105 subunit to activate target genes in the regulation of cholesterol and fatty acid homeostasis. In addition, Med15 is a critical transducer of gene activation signals that control early metazoan development.


Pssm-ID: 312941 [Multi-domain]  Cd Length: 732  Bit Score: 39.61  E-value: 2.17e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799   27 GNQPAGAGGYPGASY-PGAYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGTYPGPTAP 105
Cdd:pfam09606 320 GNHPAAHQQQMNQSVgQGGQVVALGGLNHLETWNPGNFGGLGANPMQRGQPGMMSSPSPVPGQQVRQVTPNQFMRQSPQP 399

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 308081799  106 AYPGPTAPGTQPGQPSGPGAYPPPGQPSAPGAYPAAGP 143
Cdd:pfam09606 400 SVPSPQGPGSQPPQSHPGGMIPSPALIPSPSPQMSQQP 437
SAV_2336_NTERM NF041121
SAV_2336 family N-terminal domain; This HMM describes an N-terminal domain shared by SAV_2336 ...
 67-185 2.23e-03

SAV_2336 family N-terminal domain; This HMM describes an N-terminal domain shared by SAV_2336 (BAC70047.1) whose C-terminal region suggests restriction enzyme activity (PMID: 18456708), and with other proteins with unrelated C-terminal regions. A member protein was also identified in a kanamycin biosynthetic gene cluster (PMID:16766657), while N-terminal regions of two other member proteins were named Trypco1 in a bioinformatic study (PMID:32101166) of predicted bacterial conflict systems.


Pssm-ID: 469044 [Multi-domain]  Cd Length: 473  Bit Score: 39.22  E-value: 2.23e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799  67 APPGGYPGQAPPGGYPGQAPPGGYPGQAPPGTYPGPTAPAypGPTAPGTQPGQPSGPGAYPPPGQPSAPGAypaAGPFGI 146
Cdd:NF041121  19 AAPPSPEGPAPTAASQPATPPPPAAPPSPPGDPPEPPAPE--PAPLPAPYPGSLAPPPPPPPGPAGAAPGA---ALPVRV 93

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 308081799 147 PAGPltvpydlPLPGGVK-PRMLITILGTVrPSANRLALD 185
Cdd:NF041121  94 PAPP-------ALPNPLElARALRPLKRRV-PSPRRVELD 125
PHA03247 PHA03247
large tegument protein UL36; Provisional
 19-166 2.32e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 39.54  E-value: 2.32e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799   19 PQGWPGPWGNQPAGAGGYPGASYPGAYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGT 98
Cdd:PHA03247 2775 PAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGG 2854

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 308081799   99 YPGP------TAPAYPGPTAPGTQPGQPSGPGAYPPPGQPSAPGAYPAAGPFGIPAGPLTVPYDLPLPGGVKPR 166
Cdd:PHA03247 2855 SVAPggdvrrRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQ 2928
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 17-138 2.44e-03

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 39.30  E-value: 2.44e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799   17 PNPQGW-PGPWGNQPAGAGGYP-GASYPGAYPGQAPPGGYPGQAP----PGGYPGQAPPGGYPGQAPPGGYPGQAPPGGY 90
Cdd:PRK10263  375 PAPEGYpQQSQYAQPAVQYNEPlQQPVQPQQPYYAPAAEQPAQQPyyapAPEQPAQQPYYAPAPEQPVAGNAWQAEEQQS 454

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 308081799   91 -----PGQAPPGTYPGPTAPAYPGPTAPGTQPGQPSGPGAYPPPGQPSAPGAY 138
Cdd:PRK10263  455 tfapqSTYQTEQTYQQPAAQEPLYQQPQPVEQQPVVEPEPVVEETKPARPPLY 507
Pro-rich pfam15240
Proline-rich protein; This family includes several eukaryotic proline-rich proteins.
 11-142 2.83e-03

Proline-rich protein; This family includes several eukaryotic proline-rich proteins.


Pssm-ID: 464580 [Multi-domain]  Cd Length: 167  Bit Score: 37.71  E-value: 2.83e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799   11 LSGSGNPNPQGWPGPWGNQPAGAGGYPGASYPGayPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGY 90
Cdd:pfam15240  32 ISEEEGQSQQGGQGPQGPPPGGFPPQPPASDDP--PGPPPPGGPQQPPPQGGKQKPQGPPPQGGPRPPPGKPQGPPPQGG 109

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 308081799   91 PGQAPPGTYPGPTAPAYPGPTAPgTQPGQPSGPGAyPPPGQPSAPGAYPAAG 142
Cdd:pfam15240 110 NQQQGPPPPGKPQGPPPQGGGPP-PQGGNQQGPPP-PPPGNPQGPPQRPPQP 159
PHA03247 PHA03247
large tegument protein UL36; Provisional
 25-181 2.86e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 39.15  E-value: 2.86e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799   25 PWGNQPAGAGGYPGASYPGAYPgqAPPGGYPGQAPPGGypGQAPPGGYPGQAPPGGYPGQAPPGGYP-------GQAPPG 97
Cdd:PHA03247 2819 PPAASPAGPLPPPTSAQPTAPP--PPPGPPPPSLPLGG--SVAPGGDVRRRPPSRSPAAKPAAPARPpvrrlarPAVSRS 2894

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799   98 TYPGPTAPAYPGPTAPGTQPGQPSGPGAYPPPGQPSAPGAYPAAGPfgIPAGPLTVPYDLPLPGGVKPRMLITILGTVRP 177
Cdd:PHA03247 2895 TESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQ--PPLAPTTDPAGAGEPSGAVPQPWLGALVPGRV 2972


                  ....
gi 308081799  178 SANR 181
Cdd:PHA03247 2973 AVPR 2976
PHA03247 PHA03247
large tegument protein UL36; Provisional
 8-150 2.91e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 39.15  E-value: 2.91e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799    8 NDALSGSGNPNPqGWPGPWGNQPAGAGGYPGASYPGAYP-GQAPPGGYPGQAPPGGYPGQAP-----PGGYPGQAPPGGY 81
Cdd:PHA03247 2815 AAALPPAASPAG-PLPPPTSAQPTAPPPPPGPPPPSLPLgGSVAPGGDVRRRPPSRSPAAKPaaparPPVRRLARPAVSR 2893

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 308081799   82 PGQAPPGGYPGQAPPGTYPGPTAPAYPGPTAPGTQPGQPSGPGAYPPPGQPSAPGAYPAAGPFGIPAGP 150
Cdd:PHA03247 2894 STESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQP 2962
PHA03264 PHA03264
envelope glycoprotein D; Provisional
 25-153 2.92e-03

envelope glycoprotein D; Provisional


Pssm-ID: 223029 [Multi-domain]  Cd Length: 416  Bit Score: 38.83  E-value: 2.92e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799  25 PWGNQPAGAGGYPgasypgaypgqAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGTyPGPTA 104
Cdd:PHA03264 263 GYEPPPAPSGGSP-----------APPGDDRPEAKPEPGPVEDGAPGRETGGEGEGPEPAGRDGAAGGEPKPGP-PRPAP 330

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 308081799 105 PAypgpTAPGTQPGQPSGPGAYPPPGQPSAPGAYPAAGPFGIPAGPLTV 153
Cdd:PHA03264 331 DA----DRPEGWPSLEAITFPPPTPATPAVPRARPVIVGTGIAAAAIAC 375
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 29-141 3.06e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 38.93  E-value: 3.06e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799  29 QPAGAGGYPGASYPGAYPGQAPPGGYPGQAPPggyPGQAPPGgyPGQAPPGGYPGQAPPggyPGQAPPGTYPGPTAPAYP 108
Cdd:PRK14951 386 AAAPAAAPVAQAAAAPAPAAAPAAAASAPAAP---PAAAPPA--PVAAPAAAAPAAAPA---AAPAAVALAPAPPAQAAP 457

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 308081799 109 GPTAPG--TQPGqPSGPGAYPPPGQPSAPGAYPAA 141
Cdd:PRK14951 458 ETVAIPvrVAPE-PAVASAAPAPAAAPAAARLTPT 491
SPT5 COG5164
Transcription elongation factor SPT5 [Transcription];
13-152 3.06e-03

Transcription elongation factor SPT5 [Transcription];


Pssm-ID: 444063 [Multi-domain]  Cd Length: 495  Bit Score: 38.86  E-value: 3.06e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799  13 GSGNPNPQGWPGPWGNQPAGAGGYPGASYPGAYP--GQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGY 90
Cdd:COG5164    8 KTGPSDPGGVTTPAGSQGSTKPAQNQGSTRPAGNtgGTRPAQNQGSTTPAGNTGGTRPAGNQGATGPAQNQGGTTPAQNQ 87

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 308081799  91 PGQAPPGTYPGPTAPAYPGPTAPGTQPGQPSGPGAYPPPGQPSAPGAYPAAGPFGIPAGPLT 152
Cdd:COG5164   88 GGTRPAGNTGGTTPAGDGGATGPPDDGGATGPPDDGGSTTPPSGGSTTPPGDGGSTPPGPGS 149
PHA03247 PHA03247
large tegument protein UL36; Provisional
 17-154 3.53e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 39.15  E-value: 3.53e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799   17 PNPQGWPGPwgNQPAGAGGYPGASYPGAYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPP 96
Cdd:PHA03247 2840 PPPPGPPPP--SLPLGGSVAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPP 2917

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799   97 GTYPGPTAPAYPGPTAPgtQPGQPSGPGA--YPPPGQPSAPGAYPAAGPFGIPAGPLTVP 154
Cdd:PHA03247 2918 QPQPQPPPPPQPQPPPP--PPPRPQPPLAptTDPAGAGEPSGAVPQPWLGALVPGRVAVP 2975
PBP1 COG5180
PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification]; ...
 49-165 4.09e-03

PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification];


Pssm-ID: 444064 [Multi-domain]  Cd Length: 548  Bit Score: 38.51  E-value: 4.09e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799  49 APPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGTYPGPTAPAYPGpTAPGTQPGQPSGPGAYPP 128
Cdd:COG5180  310 APPATRPVRPPGGARDPGTPRPGQPTERPAGVPEAASDAGQPPSAYPPAEEAVPGKPLEQG-APRPGSSGGDGAPFQPPN 388

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 308081799 129 PGQPSAPGAYPAAGPFGIPAGPLTVPYDLPLPGGVKP 165
Cdd:COG5180  389 GAPQPGLGRRGAPGPPMGAGDLVQAALDGGGRETASL 425
SPT5 COG5164
Transcription elongation factor SPT5 [Transcription];
24-165 4.44e-03

Transcription elongation factor SPT5 [Transcription];


Pssm-ID: 444063 [Multi-domain]  Cd Length: 495  Bit Score: 38.47  E-value: 4.44e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799  24 GPWGNQPAGAGGYPGAsyPGAYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGTYPGPT 103
Cdd:COG5164    5 GPGKTGPSDPGGVTTP--AGSQGSTKPAQNQGSTRPAGNTGGTRPAQNQGSTTPAGNTGGTRPAGNQGATGPAQNQGGTT 82

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 308081799 104 APAYPGPTAPGTQPGQPSGPGAYPPPGQPSAPGAYPAAGPFGIPAGPLTVPYDLPLPGGVKP 165
Cdd:COG5164   83 PAQNQGGTRPAGNTGGTTPAGDGGATGPPDDGGATGPPDDGGSTTPPSGGSTTPPGDGGSTP 144
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 37-150 4.70e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 38.61  E-value: 4.70e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799   37 PGASYPGAYPGQAPPGGYPGQAPPGGYPG--QAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGTYPGPTAPAYPGPTAPG 114
Cdd:PHA03307   88 PTWSLSTLAPASPAREGSPTPPGPSSPDPppPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAA 167

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 308081799  115 TQPG------------QPSGPGAYPPPGQPSAPGAYPAAGPFGIPAGP 150
Cdd:PHA03307  168 SSRQaalplsspeetaRAPSSPPAEPPPSTPPAAASPRPPRRSSPISA 215
PHA02682 PHA02682
ORF080 virion core protein; Provisional
 46-154 4.74e-03

ORF080 virion core protein; Provisional


Pssm-ID: 177464 [Multi-domain]  Cd Length: 280  Bit Score: 37.92  E-value: 4.74e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799  46 PGQAPPGGYPGQAPPGGYPGQAPPGGYPGqAPPGGYPGQAPPGGYPGQAPPGTY-PGPTAPAYPGPTAPGTQPGQPSGPG 124
Cdd:PHA02682  87 ACAAPAPACPACAPAAPAPAVTCPAPAPA-CPPATAPTCPPPAVCPAPARPAPAcPPSTRQCPPAPPLPTPKPAPAAKPI 165

                         90       100       110
                 ....*....|....*....|....*....|
gi 308081799 125 AYPppgQPSAPGAYPAAGPFGIPAGPLTVP 154
Cdd:PHA02682 166 FLH---NQLPPPDYPAASCPTIETAPAASP 192
PHA03247 PHA03247
large tegument protein UL36; Provisional
 35-154 5.15e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 38.38  E-value: 5.15e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799   35 GYPGASYPGAYPGQAPPGGYP---------GQAPPggyPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGTYPGPTaP 105
Cdd:PHA03247  341 PRPRQHYPLGFPKRRRPTWTPpssledlsaGRHHP---KRASLPTRKRRSARHAATPFARGPGGDDQTRPAAPVPASV-P 416

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 308081799  106 AYPGPTAPGTQPGQPSGPGAYPPPGQPSAPgAYPAAGPFGIPAGPLTVP 154
Cdd:PHA03247  417 TPAPTPVPASAPPPPATPLPSAEPGSDDGP-APPPERQPPAPATEPAPD 464
PHA03247 PHA03247
large tegument protein UL36; Provisional
 30-154 6.08e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 38.38  E-value: 6.08e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799   30 PAGAGGYPGASYPGAYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQA---PPGTYPGPTAPa 106
Cdd:PHA03247 2751 PGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAaalPPAASPAGPLP- 2829

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 308081799  107 yPGPTAPGTQPGQPSGPGA-YPPPGQPSAPGA-----YPAAGPFGIPAGPLTVP 154
Cdd:PHA03247 2830 -PPTSAQPTAPPPPPGPPPpSLPLGGSVAPGGdvrrrPPSRSPAAKPAAPARPP 2882
PRK14959 PRK14959
DNA polymerase III subunits gamma and tau; Provisional
 68-154 6.13e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184923 [Multi-domain]  Cd Length: 624  Bit Score: 38.12  E-value: 6.13e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799  68 PPGGypGQAPPGGYPGQAP-PGGYPGQAPPGTY-PGPTAPAyPGPTAPGTQPGQPSgPGAYPPPGQP--SAPGAYPAAG- 142
Cdd:PRK14959 373 PSGG--GASAPSGSAAEGPaSGGAATIPTPGTQgPQGTAPA-AGMTPSSAAPATPA-PSAAPSPRVPwdDAPPAPPRSGi 448

                         90
                 ....*....|...
gi 308081799 143 -PFGIPAGPLTVP 154
Cdd:PRK14959 449 pPRPAPRMPEASP 461
PHA03169 PHA03169
hypothetical protein; Provisional
 27-137 6.40e-03

hypothetical protein; Provisional


Pssm-ID: 223003 [Multi-domain]  Cd Length: 413  Bit Score: 37.64  E-value: 6.40e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799  27 GNQPAGAGGYPGASYPGAYPGQAPPGgypGQAPPGGYPGQAPPGGYPGQAPPGGYPGQaPPGGYPGQAPPGTYPGPTAPA 106
Cdd:PHA03169 125 GSSPESPASHSPPPSPPSHPGPHEPA---PPESHNPSPNQQPSSFLQPSHEDSPEEPE-PPTSEPEPDSPGPPQSETPTS 200

                         90       100       110
                 ....*....|....*....|....*....|.
gi 308081799 107 YPGPTAPGTQPGQPSGPGAYPPPGQPSAPGA 137
Cdd:PHA03169 201 SPPPQSPPDEPGEPQSPTPQQAPSPNTQQAV 231
PHA03247 PHA03247
large tegument protein UL36; Provisional
 31-141 6.47e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 38.00  E-value: 6.47e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799   31 AGAGGYPGASYPGAYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGGypgqappggypgqAPPGTYPGPTAPAYPGP 110
Cdd:PHA03247  370 AGRHHPKRASLPTRKRRSARHAATPFARGPGGDDQTRPAAPVPASVPTPA-------------PTPVPASAPPPPATPLP 436

                          90       100       110
                  ....*....|....*....|....*....|.
gi 308081799  111 TApgtQPGQPSGPgAYPPPGQPSAPGAYPAA 141
Cdd:PHA03247  437 SA---EPGSDDGP-APPPERQPPAPATEPAP 463
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
 28-123 7.09e-03

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 37.71  E-value: 7.09e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799   28 NQPAGAGGYPGASYPGAYPGQAPPGGYP---------GQAPPGGYPGQAPPGGYPGQAPP-GGYPGQ---------APPG 88
Cdd:pfam09770 235 QFPPQIQQQQQPQQQPQQPQQHPGQGHPvtilqrpqsPQPDPAQPSIQPQAQQFHQQPPPvPVQPTQilqnpnrlsAARV 314

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 308081799   89 GYPGQAPPGTYPGPTAPAYPGPTAPGTQPGQPSGP 123
Cdd:pfam09770 315 GYPQNPQPGVQPAPAHQAHRQQGSFGRQAPIITHP 349
PRK13729 PRK13729
conjugal transfer pilus assembly protein TraB; Provisional
 64-131 7.67e-03

conjugal transfer pilus assembly protein TraB; Provisional


Pssm-ID: 184281 [Multi-domain]  Cd Length: 475  Bit Score: 37.50  E-value: 7.67e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 308081799  64 PGQAPPGGYPGQAPPGGYPGQAPPGGYPGQAPPGTYPGPTAPAYPGPTA--PG---TQPGQPSGPGAyPPPGQ 131
Cdd:PRK13729 123 LGANPVTATGEPVPQMPASPPGPEGEPQPGNTPVSFPPQGSVAVPPPTAfyPGngvTPPPQVTYQSV-PVPNR 194
KREPA2 cd23959
Kinetoplastid RNA Editing Protein A2 (KREPA2); The KREPA2 (TbMP63) protein is a component of ...
 48-152 7.93e-03

Kinetoplastid RNA Editing Protein A2 (KREPA2); The KREPA2 (TbMP63) protein is a component of the parasitic protozoan's KREPA RNA editing catalytic complex (RECC). Kinetoplastid RNA editing (KRE) proteins occur as pairs or sets of related proteins in multiple complexes. KREPA complex is composed of six components (KREPA1-6), which share a conserved C-terminal region containing an oligonucleotide-binding (OB)-fold-like domain. KREPAs are responsible for the site-specific insertion and deletion of U nucleotides in the kinetoplastid mitochondria pre-messenger RNA. Apart from the conserved C-terminal OB-fold domain, KREPA1, KREPA2, and KREPA3 contain two conserved C2H2 zinc-finger domains. KREPA2 and kinetoplastid RNA editing ligase 1 (KREL1) are specific for ligation post-U-deletion and are paralogous to KREL2 and KREPA1 that are specific for ligation post-U-insertion. KREPA2, is critical for RECC stability and KREL1 integration into the complex.


Pssm-ID: 467780 [Multi-domain]  Cd Length: 424  Bit Score: 37.54  E-value: 7.93e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799  48 QAPPGGYPGQAPpggYPGQAPPGGYPGQAPPGGYPGQAPPGGYPGQ-APPGTYPGPTAPAYPGPTAPGTQPGQPSGPGAY 126
Cdd:cd23959  143 QTAPVTPFGQLP---MFGQHPPPAKPLPAAAAAQQSSASPGEVASPfASGTVSASPFATATDTAPSSGAPDGFPAEASAP 219

                         90       100
                 ....*....|....*....|....*.
gi 308081799 127 PPPGQPSAPGAYPAAGPFGIPAGPLT 152
Cdd:cd23959  220 SPFAAPASAASFPAAPVANGEAATPT 245
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 17-164 9.70e-03

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 37.37  E-value: 9.70e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799   17 PNPQGWPGPWGNQPAGAGGY-PGASYPGAYPGQAPPGgypgQAPPGGYPGQAPPGGYPGQAPPGGYPGQAP----PGGYP 91
Cdd:PRK10263  402 QPQQPYYAPAAEQPAQQPYYaPAPEQPAQQPYYAPAP----EQPVAGNAWQAEEQQSTFAPQSTYQTEQTYqqpaAQEPL 477

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308081799   92 GQAPPGTYPGPTAPayPGPTAPGTQPGQPS--------------------------GPGAYPPPGQPSAPGAYPAAGPfg 145
Cdd:PRK10263  478 YQQPQPVEQQPVVE--PEPVVEETKPARPPlyyfeeveekrarereqlaawyqpipEPVKEPEPIKSSLKAPSVAAVP-- 553

                         170
                  ....*....|....*....
gi 308081799  146 iPAGPltVPYDLPLPGGVK 164
Cdd:PRK10263  554 -PVEA--AAAVSPLASGVK 569
FAP pfam07174
Fibronectin-attachment protein (FAP); This family contains bacterial fibronectin-attachment ...
 82-140 9.94e-03

Fibronectin-attachment protein (FAP); This family contains bacterial fibronectin-attachment proteins (FAP). Family members are rich in alanine and proline, are approximately 300 long, and seem to be restricted to mycobacteria. These proteins contain a fibronectin-binding motif that allows mycobacteria to bind to fibronectin in the extracellular matrix.


Pssm-ID: 429334  Cd Length: 301  Bit Score: 36.83  E-value: 9.94e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 308081799   82 PGQAPPGGYPGQAPPGTYPGPTAPAYPGPTAPgtqPGQPSGPGAYPPPGQPSAPGAYPA 140
Cdd:pfam07174  41 PEPAPPPPSTATAPPAPPPPPPAPAAPAPPPP---PAAPNAPNAPPPPADPNAPPPPPA 96
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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