NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|333033775|ref|NP_001193938|]
View 

zinc finger protein 497 [Homo sapiens]

Protein Classification

C2H2-type zinc finger protein( domain architecture ID 11472214)

Cys2His2 (C2H2)-type zinc finger protein may be involved in transcriptional regulation

CATH:  3.30.160.60
Gene Ontology:  GO:0008270|GO:0003677
PubMed:  11361095|22803940
SCOP:  4003583

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
107-492 1.57e-18

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 88.21  E-value: 1.57e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 333033775 107 RCGECGKAFSQGSYLLQHRRVHTGEKPYTC--PECGKAFAWSSNLSQHQRIHSGEKPYacRECGKAFRAHSQLIHHQETH 184
Cdd:COG5048   35 SCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSD--LNSKSLPLSNSKASSSSLSS 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 333033775 185 SGLKPFRCPDC-GKSFGRSTTLVQHRRTHTGEKPYECPecgkaFSWNSNFLEHRRVHTGARP--HACRDCGKAFSQSSNL 261
Cdd:COG5048  113 SSSNSNDNNLLsSHSLPPSSRDPQLPDLLSISNLRNNP-----LPGNNSSSVNTPQSNSLHPplPANSLSKDPSSNLSLL 187

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 333033775 262 AeHLKIHAGARPHACPDCGKAFVRVAGLRQHRRTHSSEKPFPCAECGKAFRESSQLLQHQRTHTGERPFECAECGQAfvM 341
Cdd:COG5048  188 I-SSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRS--S 264

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 333033775 342 GSYLAEHRRVHTG---------EKPHACAQCGKAFSQRSNLLSHRRT--HSG--AKPFAC--ADCGKAF-RGSSGLAHHR 405
Cdd:COG5048  265 LPTASSQSSSPNEsdsssekgfSLPIKSKQCNISFSRSSPLTRHLRSvnHSGesLKPFSCpySLCGKLFsRNDALKRHIL 344

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 333033775 406 LsHTGERPFAC--AECGKAFRGSSELRQHQRLH-----SGERPFVCAH--CSKAFVRKSELLSHRRTHTGERPYAC--GE 474
Cdd:COG5048  345 L-HTSISPAKEklLNSSSKFSPLLNNEPPQSLQqykdlKNDKKSETLSnsCIRNFKRDSNLSLHIITHLSFRPYNCknPP 423

                        410
                 ....*....|....*...
gi 333033775 475 CGKPFSHRCNLNEHQKRH 492
Cdd:COG5048  424 CSKSFNRHYNLIPHKKIH 441
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
107-492 1.57e-18

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 88.21  E-value: 1.57e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 333033775 107 RCGECGKAFSQGSYLLQHRRVHTGEKPYTC--PECGKAFAWSSNLSQHQRIHSGEKPYacRECGKAFRAHSQLIHHQETH 184
Cdd:COG5048   35 SCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSD--LNSKSLPLSNSKASSSSLSS 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 333033775 185 SGLKPFRCPDC-GKSFGRSTTLVQHRRTHTGEKPYECPecgkaFSWNSNFLEHRRVHTGARP--HACRDCGKAFSQSSNL 261
Cdd:COG5048  113 SSSNSNDNNLLsSHSLPPSSRDPQLPDLLSISNLRNNP-----LPGNNSSSVNTPQSNSLHPplPANSLSKDPSSNLSLL 187

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 333033775 262 AeHLKIHAGARPHACPDCGKAFVRVAGLRQHRRTHSSEKPFPCAECGKAFRESSQLLQHQRTHTGERPFECAECGQAfvM 341
Cdd:COG5048  188 I-SSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRS--S 264

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 333033775 342 GSYLAEHRRVHTG---------EKPHACAQCGKAFSQRSNLLSHRRT--HSG--AKPFAC--ADCGKAF-RGSSGLAHHR 405
Cdd:COG5048  265 LPTASSQSSSPNEsdsssekgfSLPIKSKQCNISFSRSSPLTRHLRSvnHSGesLKPFSCpySLCGKLFsRNDALKRHIL 344

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 333033775 406 LsHTGERPFAC--AECGKAFRGSSELRQHQRLH-----SGERPFVCAH--CSKAFVRKSELLSHRRTHTGERPYAC--GE 474
Cdd:COG5048  345 L-HTSISPAKEklLNSSSKFSPLLNNEPPQSLQqykdlKNDKKSETLSnsCIRNFKRDSNLSLHIITHLSFRPYNCknPP 423

                        410
                 ....*....|....*...
gi 333033775 475 CGKPFSHRCNLNEHQKRH 492
Cdd:COG5048  424 CSKSFNRHYNLIPHKKIH 441
zf-H2C2_2 pfam13465
Zinc-finger double domain;
205-228 4.56e-05

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 40.43  E-value: 4.56e-05
                          10        20
                  ....*....|....*....|....
gi 333033775  205 LVQHRRTHTGEKPYECPECGKAFS 228
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFK 25
PHA00733 PHA00733
hypothetical protein
 133-180 5.98e-04

hypothetical protein


Pssm-ID: 177301  Cd Length: 128  Bit Score: 39.86  E-value: 5.98e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 333033775 133 PYTCPECGKAFAWSSNLSQHqrIHSGEKPYACRECGKAFRAHSQLIHH 180
Cdd:PHA00733  73 PYVCPLCLMPFSSSVSLKQH--IRYTEHSKVCPVCGKEFRNTDSTLDH 118
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
107-492 1.57e-18

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 88.21  E-value: 1.57e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 333033775 107 RCGECGKAFSQGSYLLQHRRVHTGEKPYTC--PECGKAFAWSSNLSQHQRIHSGEKPYacRECGKAFRAHSQLIHHQETH 184
Cdd:COG5048   35 SCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSD--LNSKSLPLSNSKASSSSLSS 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 333033775 185 SGLKPFRCPDC-GKSFGRSTTLVQHRRTHTGEKPYECPecgkaFSWNSNFLEHRRVHTGARP--HACRDCGKAFSQSSNL 261
Cdd:COG5048  113 SSSNSNDNNLLsSHSLPPSSRDPQLPDLLSISNLRNNP-----LPGNNSSSVNTPQSNSLHPplPANSLSKDPSSNLSLL 187

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 333033775 262 AeHLKIHAGARPHACPDCGKAFVRVAGLRQHRRTHSSEKPFPCAECGKAFRESSQLLQHQRTHTGERPFECAECGQAfvM 341
Cdd:COG5048  188 I-SSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRS--S 264

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 333033775 342 GSYLAEHRRVHTG---------EKPHACAQCGKAFSQRSNLLSHRRT--HSG--AKPFAC--ADCGKAF-RGSSGLAHHR 405
Cdd:COG5048  265 LPTASSQSSSPNEsdsssekgfSLPIKSKQCNISFSRSSPLTRHLRSvnHSGesLKPFSCpySLCGKLFsRNDALKRHIL 344

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 333033775 406 LsHTGERPFAC--AECGKAFRGSSELRQHQRLH-----SGERPFVCAH--CSKAFVRKSELLSHRRTHTGERPYAC--GE 474
Cdd:COG5048  345 L-HTSISPAKEklLNSSSKFSPLLNNEPPQSLQqykdlKNDKKSETLSnsCIRNFKRDSNLSLHIITHLSFRPYNCknPP 423

                        410
                 ....*....|....*...
gi 333033775 475 CGKPFSHRCNLNEHQKRH 492
Cdd:COG5048  424 CSKSFNRHYNLIPHKKIH 441
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
124-404 4.42e-14

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 74.35  E-value: 4.42e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 333033775 124 HRRVHTGEKPYTCPECGKAFAWSSNLSQHQRIHSGEKPYACRECGKAFRAHSQLIHHQETHSGLKPFRCPDCGKSfgrST 203
Cdd:COG5048  189 SSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRS---SL 265

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 333033775 204 TLVQHRRTHtgekpyecpecgkafSWNSNFLEHRRVHTgarPHACRDCGKAFSQSSNLAEHL--KIH--AGARPHACP-- 277
Cdd:COG5048  266 PTASSQSSS---------------PNESDSSSEKGFSL---PIKSKQCNISFSRSSPLTRHLrsVNHsgESLKPFSCPys 327

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 333033775 278 DCGKAFVRVAGLRQHRRTHSSEKPFPC--AECGKAFRESS-----QLLQHQRTHTGERPFECA--ECGQAFVMGSYLAEH 348
Cdd:COG5048  328 LCGKLFSRNDALKRHILLHTSISPAKEklLNSSSKFSPLLnneppQSLQQYKDLKNDKKSETLsnSCIRNFKRDSNLSLH 407

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 333033775 349 RRVHTGEKPHAC--AQCGKAFSQRSNLLSHRRTHSGAKPFACADCGKaFRGSSGLAHH 404
Cdd:COG5048  408 IITHLSFRPYNCknPPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKS-FRRDLDLSNH 464
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
106-220 1.21e-05

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 47.77  E-value: 1.21e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 333033775 106 CRCGECGKAFSQGSYLLQHRR--VHTGE--KPYTCPE--CGKAFAWSSNLSQHQRIHSGEKPYAC--RECGKAFR----- 172
Cdd:COG5048  290 IKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTSISPAKEklLNSSSKFSpllnn 369

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 333033775 173 AHSQLIHHQETHSGLKP--------------------------------FRCPDCGKSFGRSTTLVQHRRTHTGEKPYEC 220
Cdd:COG5048  370 EPPQSLQQYKDLKNDKKsetlsnscirnfkrdsnlslhiithlsfrpynCKNPPCSKSFNRHYNLIPHKKIHTNHAPLLC 449
zf-H2C2_2 pfam13465
Zinc-finger double domain;
205-228 4.56e-05

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 40.43  E-value: 4.56e-05
                          10        20
                  ....*....|....*....|....
gi 333033775  205 LVQHRRTHTGEKPYECPECGKAFS 228
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFK 25
zf-H2C2_2 pfam13465
Zinc-finger double domain;
120-144 1.35e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.89  E-value: 1.35e-04
                          10        20
                  ....*....|....*....|....*
gi 333033775  120 YLLQHRRVHTGEKPYTCPECGKAFA 144
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFK 25
zf-H2C2_2 pfam13465
Zinc-finger double domain;
148-171 1.82e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.51  E-value: 1.82e-04
                          10        20
                  ....*....|....*....|....
gi 333033775  148 NLSQHQRIHSGEKPYACRECGKAF 171
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSF 24
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 214-297 2.44e-04

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 43.55  E-value: 2.44e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 333033775 214 GEKPYECP--ECGKAFSwNSNFLEHRRVHTgarpHacrdCGKAFSQSSNLAEHLKIHAGARPHACPDCGKAFVRVAGLRQ 291
Cdd:COG5189  346 DGKPYKCPveGCNKKYK-NQNGLKYHMLHG----H----QNQKLHENPSPEKMNIFSAKDKPYRCEVCDKRYKNLNGLKY 416


                 ....*.
gi 333033775 292 HrRTHS 297
Cdd:COG5189  417 H-RKHS 421
zf-H2C2_2 pfam13465
Zinc-finger double domain;
344-369 5.79e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 37.35  E-value: 5.79e-04
                          10        20
                  ....*....|....*....|....*.
gi 333033775  344 YLAEHRRVHTGEKPHACAQCGKAFSQ 369
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
PHA00733 PHA00733
hypothetical protein
 133-180 5.98e-04

hypothetical protein


Pssm-ID: 177301  Cd Length: 128  Bit Score: 39.86  E-value: 5.98e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 333033775 133 PYTCPECGKAFAWSSNLSQHqrIHSGEKPYACRECGKAFRAHSQLIHH 180
Cdd:PHA00733  73 PYVCPLCLMPFSSSVSLKQH--IRYTEHSKVCPVCGKEFRNTDSTLDH 118
zf-H2C2_2 pfam13465
Zinc-finger double domain;
289-311 7.69e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.97  E-value: 7.69e-04
                          10        20
                  ....*....|....*....|...
gi 333033775  289 LRQHRRTHSSEKPFPCAECGKAF 311
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSF 24
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
356-449 1.46e-03

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 41.22  E-value: 1.46e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 333033775 356 KPHACAQCGKAFSQRSNLLSHRRTHSGAKPFACADCGkafrgssglahhrlshtgerpfacaeCGKAFRGSSELRQHQRL 435
Cdd:COG5048   32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSG--------------------------CDKSFSRPLELSRHLRT 85

                         90
                 ....*....|....
gi 333033775 436 HSGERPFVCAHCSK 449
Cdd:COG5048   86 HHNNPSDLNSKSLP 99
zf-H2C2_2 pfam13465
Zinc-finger double domain;
317-340 1.81e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.81  E-value: 1.81e-03
                          10        20
                  ....*....|....*....|....
gi 333033775  317 LLQHQRTHTGERPFECAECGQAFV 340
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFK 25
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 125-213 2.39e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 40.47  E-value: 2.39e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 333033775 125 RRVHTGEKPYTCP--ECGKAFAWSSNLSQHqRIHSgekpyacrECGKAFRAHSQLIHHQETHSGLKPFRCPDCGKSFGRS 202
Cdd:COG5189  341 MLKVKDGKPYKCPveGCNKKYKNQNGLKYH-MLHG--------HQNQKLHENPSPEKMNIFSAKDKPYRCEVCDKRYKNL 411

                         90
                 ....*....|.
gi 333033775 203 TTLVQHrRTHT 213
Cdd:COG5189  412 NGLKYH-RKHS 421
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 405-490 2.83e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 40.09  E-value: 2.83e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 333033775 405 RLSHTGERPFACA--ECGKAFRGSSELRQHqRLHsgerpfvcAHCSKAFVRKSELLSHRRTHTGERPYACGECGKPFSHR 482
Cdd:COG5189  341 MLKVKDGKPYKCPveGCNKKYKNQNGLKYH-MLH--------GHQNQKLHENPSPEKMNIFSAKDKPYRCEVCDKRYKNL 411


                 ....*...
gi 333033775 483 CNLNEHQK 490
Cdd:COG5189  412 NGLKYHRK 419
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 190-212 3.72e-03

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 34.97  E-value: 3.72e-03
                          10        20
                  ....*....|....*....|...
gi 333033775  190 FRCPDCGKSFGRSTTLVQHRRTH 212
Cdd:pfam00096   1 YKCPDCGKSFSRKSNLKRHLRTH 23
PHA00733 PHA00733
hypothetical protein
 189-236 4.37e-03

hypothetical protein


Pssm-ID: 177301  Cd Length: 128  Bit Score: 37.55  E-value: 4.37e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 333033775 189 PFRCPDCGKSFGRSTTLVQHRRTHTGEKpyECPECGKAFSWNSNFLEH 236
Cdd:PHA00733  73 PYVCPLCLMPFSSSVSLKQHIRYTEHSK--VCPVCGKEFRNTDSTLDH 118
PHA00733 PHA00733
hypothetical protein
 273-320 7.69e-03

hypothetical protein


Pssm-ID: 177301  Cd Length: 128  Bit Score: 36.78  E-value: 7.69e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 333033775 273 PHACPDCGKAFVRVAGLRQHRRThsSEKPFPCAECGKAFRESSQLLQH 320
Cdd:PHA00733  73 PYVCPLCLMPFSSSVSLKQHIRY--TEHSKVCPVCGKEFRNTDSTLDH 118
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH