NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|385275076|ref|NP_001245267|]
View 

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 isoform b [Homo sapiens]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
NDUFA12 super family cl47913
NADH ubiquinone oxidoreductase subunit NDUFA12; This family contains the 17.2 kD subunit of ...
 37-57 6.34e-08

NADH ubiquinone oxidoreductase subunit NDUFA12; This family contains the 17.2 kD subunit of complex I (NDUFA12) and its homologs. The family also contains a second related eukaryotic protein of unknown function,.


The actual alignment was detected with superfamily member pfam05071:

Pssm-ID: 461542  Cd Length: 96  Bit Score: 44.90  E-value: 6.34e-08
                         10        20
                 ....*....|....*....|.
gi 385275076  37 TLVGEDKYGNKYYEDNKQFFG 57
Cdd:pfam05071  1 TLVGEDEFGNKYYENKDEELP 21
PRK08183 super family cl01534
NADH:ubiquinone oxidoreductase subunit NDUFA12;
6-50 6.50e-03

NADH:ubiquinone oxidoreductase subunit NDUFA12;


The actual alignment was detected with superfamily member PLN02732:

Pssm-ID: 470241  Cd Length: 159  Bit Score: 32.59  E-value: 6.50e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 385275076   6 VLKRGLQQI--TGHGGLR------GYLRVF-----FRTNDAKVG-TLVGEDKYGNKYYE 50
Cdd:PLN02732   5 VVKSALEAIreKGLGGFLrmlreeGYLRCLadgnlLQTKIHNIGaTLVGVDKFGNKYYQ 63
 
Name Accession Description Interval E-value
NDUFA12 pfam05071
NADH ubiquinone oxidoreductase subunit NDUFA12; This family contains the 17.2 kD subunit of ...
 37-57 6.34e-08

NADH ubiquinone oxidoreductase subunit NDUFA12; This family contains the 17.2 kD subunit of complex I (NDUFA12) and its homologs. The family also contains a second related eukaryotic protein of unknown function,.


Pssm-ID: 461542  Cd Length: 96  Bit Score: 44.90  E-value: 6.34e-08
                         10        20
                 ....*....|....*....|.
gi 385275076  37 TLVGEDKYGNKYYEDNKQFFG 57
Cdd:pfam05071  1 TLVGEDEFGNKYYENKDEELP 21
PLN03095 PLN03095
NADH:ubiquinone oxidoreductase 18 kDa subunit; Provisional
 34-51 3.62e-04

NADH:ubiquinone oxidoreductase 18 kDa subunit; Provisional


Pssm-ID: 215571  Cd Length: 115  Bit Score: 35.63  E-value: 3.62e-04
                         10
                 ....*....|....*...
gi 385275076  34 KVGTLVGEDKYGNKYYED 51
Cdd:PLN03095   8 RAGRLVGEDEFGNKYYEN 25
PLN02732 PLN02732
Probable NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit
 6-50 6.50e-03

Probable NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit


Pssm-ID: 215389  Cd Length: 159  Bit Score: 32.59  E-value: 6.50e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 385275076   6 VLKRGLQQI--TGHGGLR------GYLRVF-----FRTNDAKVG-TLVGEDKYGNKYYE 50
Cdd:PLN02732   5 VVKSALEAIreKGLGGFLrmlreeGYLRCLadgnlLQTKIHNIGaTLVGVDKFGNKYYQ 63
 
Name Accession Description Interval E-value
NDUFA12 pfam05071
NADH ubiquinone oxidoreductase subunit NDUFA12; This family contains the 17.2 kD subunit of ...
 37-57 6.34e-08

NADH ubiquinone oxidoreductase subunit NDUFA12; This family contains the 17.2 kD subunit of complex I (NDUFA12) and its homologs. The family also contains a second related eukaryotic protein of unknown function,.


Pssm-ID: 461542  Cd Length: 96  Bit Score: 44.90  E-value: 6.34e-08
                         10        20
                 ....*....|....*....|.
gi 385275076  37 TLVGEDKYGNKYYEDNKQFFG 57
Cdd:pfam05071  1 TLVGEDEFGNKYYENKDEELP 21
PLN03095 PLN03095
NADH:ubiquinone oxidoreductase 18 kDa subunit; Provisional
 34-51 3.62e-04

NADH:ubiquinone oxidoreductase 18 kDa subunit; Provisional


Pssm-ID: 215571  Cd Length: 115  Bit Score: 35.63  E-value: 3.62e-04
                         10
                 ....*....|....*...
gi 385275076  34 KVGTLVGEDKYGNKYYED 51
Cdd:PLN03095   8 RAGRLVGEDEFGNKYYEN 25
PRK08183 PRK08183
NADH:ubiquinone oxidoreductase subunit NDUFA12;
36-50 2.66e-03

NADH:ubiquinone oxidoreductase subunit NDUFA12;


Pssm-ID: 236176 [Multi-domain]  Cd Length: 133  Bit Score: 33.42  E-value: 2.66e-03
                         10
                 ....*....|....*
gi 385275076  36 GTLVGEDKYGNKYYE 50
Cdd:PRK08183  26 GERVGEDEFGNVYYR 40
PLN02732 PLN02732
Probable NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit
 6-50 6.50e-03

Probable NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit


Pssm-ID: 215389  Cd Length: 159  Bit Score: 32.59  E-value: 6.50e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 385275076   6 VLKRGLQQI--TGHGGLR------GYLRVF-----FRTNDAKVG-TLVGEDKYGNKYYE 50
Cdd:PLN02732   5 VVKSALEAIreKGLGGFLrmlreeGYLRCLadgnlLQTKIHNIGaTLVGVDKFGNKYYQ 63
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH