NCBI Conserved Domain Search

Conserved domains on [gi|525507360|ref|NP_001267480|]

View

paired box protein Pax-5 isoform 6 [Homo sapiens]

Protein Classification

helix-turn-helix domain-containing protein( domain architecture ID 229396)

helix-turn-helix domain-containing protein may bind DNA and be involved in the regulation of gene expression

Gene Ontology: GO:0003677|GO:0006355

Graphical summary

Zoom to residue level

show extra options »

Show site features Horizontal zoom: ×

List of domain hits

Name

Accession

Description

Interval

E-value

HTH_ARSR super family

cl46857

Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric ...

1-34

1.07e-14

Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.

The actual alignment was detected with superfamily member cd00131:

Pssm-ID: 481197 Cd Length: 128 Bit Score: 67.83 E-value: 1.07e-14

                         10        20        30
                 ....*....|....*....|....*....|....
gi 525507360   1 MFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTK 34
Cdd:cd00131   94 MFAWEIRDRLLQEGVCDKSNVPSVSSINRILRNK 127

Name

Accession

Description

Interval

E-value

PAX

cd00131

Paired Box domain

1-34

1.07e-14

Paired Box domain

Pssm-ID: 238076 Cd Length: 128 Bit Score: 67.83 E-value: 1.07e-14

                         10        20        30
                 ....*....|....*....|....*....|....
gi 525507360   1 MFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTK 34
Cdd:cd00131   94 MFAWEIRDRLLQEGVCDKSNVPSVSSINRILRNK 127

PAX

smart00351

Paired Box domain;

1-32

1.39e-14

Paired Box domain;

Pssm-ID: 128645 [Multi-domain] Cd Length: 125 Bit Score: 67.73 E-value: 1.39e-14

                           10        20        30
                   ....*....|....*....|....*....|..
gi 525507360     1 MFAWEIRDRLLAERVCDNDTVPSVSSINRIIR 32
Cdd:smart00351  94 IFAWEIRDRLLSEGVCDKDNVPSVSSINRILR 125

PAX

pfam00292

'Paired box' domain;

1-32

2.93e-13

'Paired box' domain;

Pssm-ID: 366005 Cd Length: 125 Bit Score: 64.12 E-value: 2.93e-13

                          10        20        30
                  ....*....|....*....|....*....|..
gi 525507360    1 MFAWEIRDRLLAERVCDNDTVPSVSSINRIIR 32
Cdd:pfam00292  94 IFAWEIRDRLLKEGVCDNDTVPSVSSINRILR 125

Name

Accession

Description

Interval

E-value

PAX

cd00131

Paired Box domain

1-34

1.07e-14

Paired Box domain

Pssm-ID: 238076 Cd Length: 128 Bit Score: 67.83 E-value: 1.07e-14

                         10        20        30
                 ....*....|....*....|....*....|....
gi 525507360   1 MFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTK 34
Cdd:cd00131   94 MFAWEIRDRLLQEGVCDKSNVPSVSSINRILRNK 127

PAX

smart00351

Paired Box domain;

1-32

1.39e-14

Paired Box domain;

Pssm-ID: 128645 [Multi-domain] Cd Length: 125 Bit Score: 67.73 E-value: 1.39e-14

                           10        20        30
                   ....*....|....*....|....*....|..
gi 525507360     1 MFAWEIRDRLLAERVCDNDTVPSVSSINRIIR 32
Cdd:smart00351  94 IFAWEIRDRLLSEGVCDKDNVPSVSSINRILR 125

PAX

pfam00292

'Paired box' domain;

1-32

2.93e-13

'Paired box' domain;

Pssm-ID: 366005 Cd Length: 125 Bit Score: 64.12 E-value: 2.93e-13

                          10        20        30
                  ....*....|....*....|....*....|..
gi 525507360    1 MFAWEIRDRLLAERVCDNDTVPSVSSINRIIR 32
Cdd:pfam00292  94 IFAWEIRDRLLKEGVCDNDTVPSVSSINRILR 125

Blast search parameters

Data Source:	Precalculated data, version = cdd.v.3.21
Preset Options:	Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01