COMM domain-containing protein 4 isoform 3 [Homo sapiens]
Protein Classification
COMM domain-containing protein( domain architecture ID 4715)
COMM (copper metabolism gene MURR1) domain-containing protein is involved in protein-protein interactions
List of domain hits
| Name | Accession | Description | Interval | E-value | ||
| Commd super family | cl06336 | COMM_Domain, a family of domains found at the C-terminus of HCarG, the copper metabolism gene ... |
25-101 | 5.97e-46 | ||
COMM_Domain, a family of domains found at the C-terminus of HCarG, the copper metabolism gene MURR1 product, and related proteins. Presumably all COMM_Domain containing proteins are located in the nucleus and the COMM domain plays a role in protein-protein interactions. Several family members have been shown to bind and inhibit NF-kappaB. Murr1/Commd1 is a protein involved in copper homeostasis, which has also been identified as a regulator of the human delta epithelial sodium channel. HCaRG, a nuclear protein that might be involved in cell proliferation, is negatively regulated by extracellular calcium concentration, and its basal mRNA levels are higher in hypertensive animals. The actual alignment was detected with superfamily member cd04752: Pssm-ID: 471425 [Multi-domain] Cd Length: 174 Bit Score: 146.04 E-value: 5.97e-46
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| Name | Accession | Description | Interval | E-value | ||
| Commd4 | cd04752 | COMM_Domain containing protein 4. The COMM Domain is found at the C-terminus of a variety of ... |
25-101 | 5.97e-46 | ||
COMM_Domain containing protein 4. The COMM Domain is found at the C-terminus of a variety of proteins; presumably all COMM_Domain containing proteins are located in the nucleus and the COMM domain plays a role in protein-protein interactions. Several family members have been shown to bind and inhibit NF-kappaB. Pssm-ID: 240100 [Multi-domain] Cd Length: 174 Bit Score: 146.04 E-value: 5.97e-46
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| Name | Accession | Description | Interval | E-value | ||
| Commd4 | cd04752 | COMM_Domain containing protein 4. The COMM Domain is found at the C-terminus of a variety of ... |
25-101 | 5.97e-46 | ||
COMM_Domain containing protein 4. The COMM Domain is found at the C-terminus of a variety of proteins; presumably all COMM_Domain containing proteins are located in the nucleus and the COMM domain plays a role in protein-protein interactions. Several family members have been shown to bind and inhibit NF-kappaB. Pssm-ID: 240100 [Multi-domain] Cd Length: 174 Bit Score: 146.04 E-value: 5.97e-46
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