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Conserved domains on  [gi|549432981|ref|NP_001272329|]
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aryl-hydrocarbon-interacting protein-like 1 isoform 5 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Spy super family cl27809
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 156-278 5.18e-06

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


The actual alignment was detected with superfamily member COG3914:

Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 48.45  E-value: 5.18e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549432981 156 VPVLHGEGNRLFKLGRYEEASSKYQEAIiclrnlqtKEKPWEVQWLklekmintliLNYCQCLLKKEEYYEVLEHTSDIL 235
Cdd:COG3914  112 AEALFNLGNLLLALGRLEEALAALRRAL--------ALNPDFAEAY----------LNLGEALRRLGRLEEAIAALRRAL 173

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 549432981 236 RHHPGIVKAYYVRARAHAEVWNEAEAKADLQKVLELEPSMQKA 278
Cdd:COG3914  174 ELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADA 216
 
Name Accession Description Interval E-value
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 156-278 5.18e-06

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 48.45  E-value: 5.18e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549432981 156 VPVLHGEGNRLFKLGRYEEASSKYQEAIiclrnlqtKEKPWEVQWLklekmintliLNYCQCLLKKEEYYEVLEHTSDIL 235
Cdd:COG3914  112 AEALFNLGNLLLALGRLEEALAALRRAL--------ALNPDFAEAY----------LNLGEALRRLGRLEEAIAALRRAL 173

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 549432981 236 RHHPGIVKAYYVRARAHAEVWNEAEAKADLQKVLELEPSMQKA 278
Cdd:COG3914  174 ELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADA 216
PLN03088 PLN03088
SGT1, suppressor of G2 allele of SKP1; Provisional
 239-282 2.12e-03

SGT1, suppressor of G2 allele of SKP1; Provisional


Pssm-ID: 215568 [Multi-domain]  Cd Length: 356  Bit Score: 39.77  E-value: 2.12e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....
gi 549432981 239 PGIVKAYYVRARAHAEVWNEAEAKADLQKVLELEPSMQKAVRRE 282
Cdd:PLN03088  33 PNNAELYADRAQANIKLGNFTEAVADANKAIELDPSLAKAYLRK 76
 
Name Accession Description Interval E-value
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 156-278 5.18e-06

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 48.45  E-value: 5.18e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549432981 156 VPVLHGEGNRLFKLGRYEEASSKYQEAIiclrnlqtKEKPWEVQWLklekmintliLNYCQCLLKKEEYYEVLEHTSDIL 235
Cdd:COG3914  112 AEALFNLGNLLLALGRLEEALAALRRAL--------ALNPDFAEAY----------LNLGEALRRLGRLEEAIAALRRAL 173

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 549432981 236 RHHPGIVKAYYVRARAHAEVWNEAEAKADLQKVLELEPSMQKA 278
Cdd:COG3914  174 ELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADA 216
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 166-292 3.83e-05

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 43.07  E-value: 3.83e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549432981 166 LFKLGRYEEASSKYQEAIICLRNLqTKEKPWEVQWLklekmintliLNYCQCLLKKEEYYEVLEHTSDILRHHPGIVKAY 245
Cdd:COG4235   20 WLLLGRAYLRLGRYDEALAAYEKA-LRLDPDNADAL----------LDLAEALLAAGDTEEAEELLERALALDPDNPEAL 88

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 549432981 246 YVRARAHAEVWNEAEAKADLQKVLELEPSmqkavRRELRLLENRMAE 292
Cdd:COG4235   89 YLLGLAAFQQGDYAEAIAAWQKLLALLPA-----DAPARLLEASIAE 130
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
158-274 7.69e-05

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 43.84  E-value: 7.69e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549432981 158 VLHGEGNRLFKLGRYEEASSKYQEAIiclrnlqtKEKPWEVQwlklekmintLILNYCQCLLKKEEYYEVLEHTSDILRH 237
Cdd:COG0457   10 AYNNLGLAYRRLGRYEEAIEDYEKAL--------ELDPDDAE----------ALYNLGLAYLRLGRYEEALADYEQALEL 71

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 549432981 238 HPGIVKAYYVRARAHAEVWNEAEAKADLQKVLELEPS 274
Cdd:COG0457   72 DPDDAEALNNLGLALQALGRYEEALEDYDKALELDPD 108
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 112-273 1.12e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 42.25  E-value: 1.12e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549432981 112 YEDLDELQKEPQPLVFVIELLQVDAPSDYQRETWNLSNHEKMKAVPVLHGEGNRLFKLGRYEEASSKYQEAiiclrnlqt 191
Cdd:COG5010   10 LPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQA--------- 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549432981 192 kekpwevqwLKLEKMINTLILNYCQCLLKKEEYYEVLEHTSDILRHHPGIVKAYYVRARAHAEVWNEAEAKADLQKVLEL 271
Cdd:COG5010   81 ---------LQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGT 151


                 ..
gi 549432981 272 EP 273
Cdd:COG5010  152 SP 153
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
158-300 1.78e-04

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 42.69  E-value: 1.78e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549432981 158 VLHGEGNRLFKLGRYEEASSKYQEAiiclrnlqtkekpwevqwLKLEKMINTLILNYCQCLLKKEEYYEVLEHTSDILRH 237
Cdd:COG0457   78 ALNNLGLALQALGRYEEALEDYDKA------------------LELDPDDAEALYNLGLALLELGRYDEAIEAYERALEL 139

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 549432981 238 HPGIVKAYYVRARAHAEVWNEAEAKADLQKVLELEPSMQKAVRRELRLLENRMAEKQEEERLR 300
Cdd:COG0457  140 DPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLA 202
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 167-300 2.25e-04

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 42.41  E-value: 2.25e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549432981 167 FKLGRYEEA----------SSKYQEAIICLRNLQTKEKPWE--VQWL-KLEKMINTLILNYC---QCLLKKEEYYEVLEH 230
Cdd:COG2956   87 LKAGLLDRAeellekllelDPDDAEALRLLAEIYEQEGDWEkaIEVLeRLLKLGPENAHAYCelaELYLEQGDYDEAIEA 166

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549432981 231 TSDILRHHPGIVKAYYVRARAHAEVWNEAEAKADLQKVLELEPSMQKAVRRELRLLENRMAEKQEEERLR 300
Cdd:COG2956  167 LEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLR 236
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
158-288 2.93e-04

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 41.92  E-value: 2.93e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549432981 158 VLHGEGNRLFKLGRYEEASSKYQEAIiclrnlqtKEKPwevqwlkleKMINTLiLNYCQCLLKKEEYYEVLEHTSDILRH 237
Cdd:COG0457   44 ALYNLGLAYLRLGRYEEALADYEQAL--------ELDP---------DDAEAL-NNLGLALQALGRYEEALEDYDKALEL 105

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 549432981 238 HPGIVKAYYVRARAHAEVWNEAEAKADLQKVLELEPSMQKAVRRELRLLEN 288
Cdd:COG0457  106 DPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEK 156
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
166-274 5.12e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 38.61  E-value: 5.12e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549432981 166 LFKLGRYEEASSKYQEAiiclrnlqtkekpwevqwLKLEKMINTLILNYCQCLLKKEEYYEVLEHTSdILRHHPGIVKAY 245
Cdd:COG3063    2 YLKLGDLEEAEEYYEKA------------------LELDPDNADALNNLGLLLLEQGRYDEAIALEK-ALKLDPNNAEAL 62

                         90       100
                 ....*....|....*....|....*....
gi 549432981 246 YVRARAHAEVWNEAEAKADLQKVLELEPS 274
Cdd:COG3063   63 LNLAELLLELGDYDEALAYLERALELDPS 91
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 156-273 8.37e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 39.02  E-value: 8.37e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549432981 156 VPVLHGEGNRLFKLGRYEEASSKYQEAIiclrnlqtKEKPWEVQWLklekmintliLNYCQCLLKKEEYYEVLEHTSDIL 235
Cdd:COG4783   38 PEAFALLGEILLQLGDLDEAIVLLHEAL--------ELDPDEPEAR----------LNLGLALLKAGDYDEALALLEKAL 99

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 549432981 236 RHHPGIVKAYYVRARAHAEVWNEAEAKADLQKVLELEP 273
Cdd:COG4783  100 KLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDP 137
PLN03088 PLN03088
SGT1, suppressor of G2 allele of SKP1; Provisional
 239-282 2.12e-03

SGT1, suppressor of G2 allele of SKP1; Provisional


Pssm-ID: 215568 [Multi-domain]  Cd Length: 356  Bit Score: 39.77  E-value: 2.12e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....
gi 549432981 239 PGIVKAYYVRARAHAEVWNEAEAKADLQKVLELEPSMQKAVRRE 282
Cdd:PLN03088  33 PNNAELYADRAQANIKLGNFTEAVADANKAIELDPSLAKAYLRK 76
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 163-296 6.94e-03

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 37.79  E-value: 6.94e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549432981 163 GNRLFKLGRYEEASSKYQEAII----CLRNLqtkekpwevqwlklekmintliLNYCQCLLKKEEYYEVLEHTSDILRHH 238
Cdd:COG2956  151 AELYLEQGDYDEAIEALEKALKldpdCARAL----------------------LLLAELYLEQGDYEEAIAALERALEQD 208

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 549432981 239 PGIVKAYYVRARAHAEVWNEAEAKADLQKVLELEPSMQKAVRRELRLLENRMAEKQEE 296
Cdd:COG2956  209 PDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLLLALADLLERKEGLEAALA 266
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
139-281 7.18e-03

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 37.59  E-value: 7.18e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 549432981 139 DYQRETWNLSNHEKMKAVPVLHGEGNRLFKLGRYEEASSKYQEAIICLRNLQTKEKPWEVQWL-KLEKMINTLILNYcqc 217
Cdd:COG4785    7 ALLLALALAAAAASKAAILLAALLFAAVLALAIALADLALALAAAALAAAALAAERIDRALALpDLAQLYYERGVAY--- 83

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 549432981 218 lLKKEEYYEVLEHTSDILRHHPGIVKAYYVRARAHAEVWNEAEAKADLQKVLELEPSMQKAVRR 281
Cdd:COG4785   84 -DSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLN 146
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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