|
Name |
Accession |
Description |
Interval |
E-value |
| CortBP2 |
pfam09727 |
Cortactin-binding protein-2; This entry is the first approximately 250 residues of ... |
77-258 |
5.07e-72 |
|
Cortactin-binding protein-2; This entry is the first approximately 250 residues of cortactin-binding protein 2. In addition to being a positional candidate for autism this protein is expressed at highest levels in the brain in humans. The human protein has six associated ankyrin repeat domains pfam00023 towards the C-terminus which act as protein-protein interaction domains.
Pssm-ID: 462860 [Multi-domain] Cd Length: 187 Bit Score: 237.88 E-value: 5.07e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 77 ELSKEDLIQLLSIMEGELQAREDVIHMLKTEKTKPEVLEAHYGSAEPEKVLRVLHRDAILAQEKSIGEDVYE----KPIS 152
Cdd:pfam09727 1 DLSKDDLLKLLSILEGELQARDIVIAVLKAEKVKQLLLEARYGFKYPSDPLLALQRDSELLRDQSQDEDVYEamyeKPLA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 153 ELDRLEEKQKETYRRMLEQLLLAEKCHRRTVYELENEKHKHTDYMNKSDDFTNLLEQERERLKKLLEQEKAYQARKEKEN 232
Cdd:pfam09727 81 ELEKLVEKQRETQRRMLEQLAAAEKRHRRVIRELEEEKRKHARDTAQGDDFTYLLEKERERLKQELEQEKAQQKRLEKEL 160
|
170 180
....*....|....*....|....*.
gi 585420407 233 AKRLNKLRDELVKLKSFALMLVDERQ 258
Cdd:pfam09727 161 KKLLEKLEEELSKQKQIALLLVKERK 186
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
208-741 |
1.30e-21 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 101.68 E-value: 1.30e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 208 EQERERLKKLLEQEKAYQARKEKENAKRLNKLRDELVKLKSfALMLVDERQMHIEQLGLQSQKVQdltQKLREEEEKLKA 287
Cdd:PRK03918 188 TENIEELIKEKEKELEEVLREINEISSELPELREELEKLEK-EVKELEELKEEIEELEKELESLE---GSKRKLEEKIRE 263
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 288 ITSKSKEDRQKLLKLEV---------DFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLTQRIEELEETNKNLQKA 358
Cdd:PRK03918 264 LEERIEELKKEIEELEEkvkelkelkEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEEL 343
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 359 EEELQELRDKIAKGECGNS------SLMAEVENLRKRVlemegKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQ 432
Cdd:PRK03918 344 KKKLKELEKRLEELEERHElyeeakAKKEELERLKKRL-----TGLTPEKLEKELEELEKAKEEIEEEISKITARIGELK 418
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 433 KRMSELEKLEEAFSKSKSEC--TQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVM 510
Cdd:PRK03918 419 KEIKELKKAIEELKKAKGKCpvCGRELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKL 498
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 511 --LVDERKNM--------MEKIKQEERKVDGLNKNFKVEQGKVMDVtEKLIEESKKLLKLKSEMEEKVYNLTRERDELIG 580
Cdd:PRK03918 499 keLAEQLKELeeklkkynLEELEKKAEEYEKLKEKLIKLKGEIKSL-KKELEKLEELKKKLAELEKKLDELEEELAELLK 577
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 581 KLKSEEEKsselscSVDLLKKRLDGIEEVEREITRGRSRKgSELtcpeDNKIKELTLEIERLKKRLQQLEVVEGDLMKTE 660
Cdd:PRK03918 578 ELEELGFE------SVEELEERLKELEPFYNEYLELKDAE-KEL----EREEKELKKLEEELDKAFEELAETEKRLEELR 646
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 661 DEYDQLEQKFRTEQ---------DKANFLSQQLEEIKHQIAKNKAIEKG-EVVSQEAELRHRFRLEEAKSRDLKAEVQAL 730
Cdd:PRK03918 647 KELEELEKKYSEEEyeelreeylELSRELAGLRAELEELEKRREEIKKTlEKLKEELEEREKAKKELEKLEKALERVEEL 726
|
570
....*....|.
gi 585420407 731 KEKIHELMNKE 741
Cdd:PRK03918 727 REKVKKYKALL 737
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
148-782 |
5.70e-17 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 87.12 E-value: 5.70e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 148 EKPISELDRLEEKQKETYRRMLEQLLLAEKCHRRTVYELENEKHKHTDYMNKSDDFTNLLEQERERLKKLLEQEKAYQAR 227
Cdd:PTZ00121 1211 ERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKK 1290
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 228 KEKENAKRLNKLRDELVKLKSFALMLVDERQMHIEQlglQSQKVQDLTQKLREEEEKLKAITSKSKEDRQKLLKLEVDFE 307
Cdd:PTZ00121 1291 KADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEE---AKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAE 1367
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 308 HKASRFSQEHEEMNA--KLANQESHNRQLRLKLVGLTQRIEELEETNKNLQKAEEELQELRDKIAKGECGNSSLMAEVEN 385
Cdd:PTZ00121 1368 AAEKKKEEAKKKADAakKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKAD 1447
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 386 LRKRVLEMEGKDEEITKTESQCR--ELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAfsKSKSEctqlHLNLEKEK 463
Cdd:PTZ00121 1448 EAKKKAEEAKKAEEAKKKAEEAKkaDEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEA--KKKAD----EAKKAEEA 1521
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 464 NLTKDLLNELEvvKSRVKELECSESRLEKAELSLKDDLTKlksftvmlVDERKNMMEKIKQEERKVDGLNKN---FKVEQ 540
Cdd:PTZ00121 1522 KKADEAKKAEE--AKKADEAKKAEEKKKADELKKAEELKK--------AEEKKKAEEAKKAEEDKNMALRKAeeaKKAEE 1591
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 541 GKVMDVTEKLIEESK-KLLKLKSEMEEKVynltrERDELIGKLKSEEEKSSELSCSVDLLKKrldgIEEVEREITRGRSR 619
Cdd:PTZ00121 1592 ARIEEVMKLYEEEKKmKAEEAKKAEEAKI-----KAEELKKAEEEKKKVEQLKKKEAEEKKK----AEELKKAEEENKIK 1662
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 620 KGSELTCPEDNKIK--ELTLEIERLKKRLQQLEVVEGDLMKTEdeydQLEQKFRTEQDKANFLSQQLEE--IKHQIAKNK 695
Cdd:PTZ00121 1663 AAEEAKKAEEDKKKaeEAKKAEEDEKKAAEALKKEAEEAKKAE----ELKKKEAEEKKKAEELKKAEEEnkIKAEEAKKE 1738
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 696 AIE---KGEVVSQEAE----LRHRFRLEEAKSRDLKAEVQALkekIHELMNKEDQLSQLQVDYSVlQQRFMEEEN--KNK 766
Cdd:PTZ00121 1739 AEEdkkKAEEAKKDEEekkkIAHLKKEEEKKAEEIRKEKEAV---IEEELDEEDEKRRMEVDKKI-KDIFDNFANiiEGG 1814
|
650
....*....|....*.
gi 585420407 767 NMGQEVLNLTKELELS 782
Cdd:PTZ00121 1815 KEGNLVINDSKEMEDS 1830
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
197-528 |
4.33e-16 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 83.95 E-value: 4.33e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 197 MNKSDDFTNLLEQERERLKKLLEQEKAYQARKEKEN-------AKRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQ 269
Cdd:TIGR02168 188 LDRLEDILNELERQLKSLERQAEKAERYKELKAELRelelallVLRLEELREELEELQEELKEAEEELEELTAELQELEE 267
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 270 KVQDLTQKLREEEEKLKAITSKSKEDRQKLLKLEVDFEHKASRFSQ---EHEEMNAKLANQESHNRQLRLKLVGLTQRIE 346
Cdd:TIGR02168 268 KLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANlerQLEELEAQLEELESKLDELAEELAELEEKLE 347
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 347 ELEEtnkNLQKAEEELQELRDKIAKGECGNSSLMAEVENLRKRVLEMEgkdEEITKTESQCRELRKKLQEEEHHSKELRL 426
Cdd:TIGR02168 348 ELKE---ELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLE---LQIASLNNEIERLEARLERLEDRRERLQQ 421
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 427 EVEKLQKRMSELEKLEeafsksksectqLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKS 506
Cdd:TIGR02168 422 EIEELLKKLEEAELKE------------LQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQA 489
|
330 340
....*....|....*....|..
gi 585420407 507 ftvmlvdeRKNMMEKIKQEERK 528
Cdd:TIGR02168 490 --------RLDSLERLQENLEG 503
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
207-762 |
1.27e-15 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 82.29 E-value: 1.27e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 207 LEQERERLKKLLEQEKAYQARKEKENAKRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLK 286
Cdd:COG1196 205 LERQAEKAERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELE 284
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 287 AITSKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLTQRIEELEETNKNLQKAEEELQELR 366
Cdd:COG1196 285 EAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAE 364
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 367 DKiakgecgnssLMAEVENLRKRVLEMEGKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQkrmSELEKLEEAFS 446
Cdd:COG1196 365 EA----------LLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLE---EELEELEEALA 431
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 447 KSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIkQEE 526
Cdd:COG1196 432 ELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFL-EGV 510
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 527 RKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYNLTRERDELIGKLKSEEEKSSELSCSVDLLKKRLDGI 606
Cdd:COG1196 511 KAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAA 590
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 607 EEVEREITRGRSRKGSELTC------PEDNKIKELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFL 680
Cdd:COG1196 591 ALARGAIGAAVDLVASDLREadaryyVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRREL 670
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 681 SQQLEEIKHQIAKnkaiEKGEVVSQEAELRHRFRLEEAKSRDLKAEVQALKEKIHELMNKEDQLSQLQVDYSVLQQRFME 760
Cdd:COG1196 671 LAALLEAEAELEE----LAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEE 746
|
..
gi 585420407 761 EE 762
Cdd:COG1196 747 LL 748
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
253-788 |
5.95e-15 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 80.11 E-value: 5.95e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 253 LVDERQMHIEQLGLQSQKVQDLTQKLREE-EEKLKAITSKSKEDRQ---KLLKLEVDFEHKASRFSqEHEEMNAKLANQE 328
Cdd:PRK03918 173 EIKRRIERLEKFIKRTENIEELIKEKEKElEEVLREINEISSELPElreELEKLEKEVKELEELKE-EIEELEKELESLE 251
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 329 SHNRQLRLKLVGLTQRIEELEETNKNLQKAEEELQELRDKIAKGEcgnsSLMAEVENLRKRVLEMEgkdEEITKTESQCR 408
Cdd:PRK03918 252 GSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYI----KLSEFYEEYLDELREIE---KRLSRLEEEIN 324
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 409 ELRKKLQEEEHHS---KELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLEKEKNLTKdllnelEVVKSRVKELEC 485
Cdd:PRK03918 325 GIEERIKELEEKEerlEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTP------EKLEKELEELEK 398
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 486 SESRLEKAELSLKDDLTKLKSftvmLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKvmDVTEKLIEESKKLLKLKSEME 565
Cdd:PRK03918 399 AKEEIEEEISKITARIGELKK----EIKELKKAIEELKKAKGKCPVCGRELTEEHRK--ELLEEYTAELKRIEKELKEIE 472
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 566 EKVYNLTRERDELIGKLKSEEEKSSelscsvdlLKKRLDGIEEVEreitrgrsrkgSELTCPEDNKIKELTLEIERLKKR 645
Cdd:PRK03918 473 EKERKLRKELRELEKVLKKESELIK--------LKELAEQLKELE-----------EKLKKYNLEELEKKAEEYEKLKEK 533
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 646 LQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQIAKN--KAIEKGEVVSQEAELRHRFRLE------- 716
Cdd:PRK03918 534 LIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELgfESVEELEERLKELEPFYNEYLElkdaeke 613
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 585420407 717 -EAKSRDLKAEVQALKEKIHELMNKEDQLSQLQVDYSVLQQRFMEEENKNKNmgqevlnlTKELELSKRYSRA 788
Cdd:PRK03918 614 lEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELR--------EEYLELSRELAGL 678
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
200-837 |
7.85e-15 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 80.19 E-value: 7.85e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 200 SDDFTNLLEQERERLKKLLEQEKAYQARKEKENAKRLNKLRD-------------ELVKLKSFALMLVDERQMHIEQLGL 266
Cdd:PTZ00121 1094 EEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKaedarkaeearkaEDAKRVEIARKAEDARKAEEARKAE 1173
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 267 QSQKVQDL--------TQKLREEEEKLKAITSKSKEDRQKLLKLEVDFEHKASRFSQEHEEM-----NAKLANQESHNRQ 333
Cdd:PTZ00121 1174 DAKKAEAArkaeevrkAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAkkdaeEAKKAEEERNNEE 1253
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 334 LRLKLVGLTQRIEELEETNKNLQKAE-EELQELRDKIAKGECGNSSLMAEVENLRKRVLEMEGKDEEITKTES---QCRE 409
Cdd:PTZ00121 1254 IRKFEEARMAHFARRQAAIKAEEARKaDELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEakkKADA 1333
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 410 LRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLEK---EKNLTKDLLNELEVVKSRVKELEcs 486
Cdd:PTZ00121 1334 AKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKkaeEKKKADEAKKKAEEDKKKADELK-- 1411
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 487 esrlEKAELSLKDDLTKLKSFTVMLVDERKnmmeKIKQEERKVDGLNKnfKVEQGKVMDVTEKLIEESKKLLKLKSEMEE 566
Cdd:PTZ00121 1412 ----KAAAAKKKADEAKKKAEEKKKADEAK----KKAEEAKKADEAKK--KAEEAKKAEEAKKKAEEAKKADEAKKKAEE 1481
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 567 KvynltRERDELigklkseEEKSSELSCSVDLLKKRLDGIEEVEREITRGRSRKGSELTCPEDNKIKELTLEIERLKKrl 646
Cdd:PTZ00121 1482 A-----KKADEA-------KKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKK-- 1547
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 647 qQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFL-----SQQLEEIKHQIAKNKAIEKGEVVSQEA--ELRHRFRLEEA- 718
Cdd:PTZ00121 1548 -ADELKKAEELKKAEEKKKAEEAKKAEEDKNMALrkaeeAKKAEEARIEEVMKLYEEEKKMKAEEAkkAEEAKIKAEELk 1626
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 719 KSRDLKAEVQALKEKIHELMNKEDQLSQLQVDYSVLQQRFMEEENKNKNMGQEvlnLTKELELSKRYSRALRPSVNGRRM 798
Cdd:PTZ00121 1627 KAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEE---AKKAEEDEKKAAEALKKEAEEAKK 1703
|
650 660 670
....*....|....*....|....*....|....*....
gi 585420407 799 VdvpvtstgvqtDAVSGEAAEEETPAVFIRKSfQEENHI 837
Cdd:PTZ00121 1704 A-----------EELKKKEAEEKKKAEELKKA-EEENKI 1730
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
144-699 |
1.48e-14 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 78.95 E-value: 1.48e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 144 EDVYEKPISELDRLEEKQK--ETYRRMLEQLLLAEKCHRRTVYELENEKHKHTDYMNKSDDFTNLLEQERERLKKLLEQE 221
Cdd:PRK03918 213 SSELPELREELEKLEKEVKelEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKA 292
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 222 KAYQARKE--KENAKRLNKLRDELVKLKSfalmLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAITSKSKEDRQKL 299
Cdd:PRK03918 293 EEYIKLSEfyEEYLDELREIEKRLSRLEE----EINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAK 368
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 300 LKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLTQRIEELEETNKNLQKAEEELQElrdkiAKGECGN--- 376
Cdd:PRK03918 369 AKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKK-----AKGKCPVcgr 443
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 377 -----------SSLMAEVENLRKRVLEMEGKDEEITKTEsqcRELRKKLQEEEHHSKELRL--EVEKLQKRMSE--LEKL 441
Cdd:PRK03918 444 elteehrkellEEYTAELKRIEKELKEIEEKERKLRKEL---RELEKVLKKESELIKLKELaeQLKELEEKLKKynLEEL 520
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 442 EEAfSKSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEK 521
Cdd:PRK03918 521 EKK-AEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEP 599
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 522 IKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEkvynltrerdeligklkseeeksselscsvdlLKK 601
Cdd:PRK03918 600 FYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEE--------------------------------LRK 647
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 602 RLdgiEEVEREITRGRSRKGSELTCPEDNKIKELTLEIERLKKRLQQlevVEGDLMKTEDEYDQLEQKfRTEQDKANFLS 681
Cdd:PRK03918 648 EL---EELEKKYSEEEYEELREEYLELSRELAGLRAELEELEKRREE---IKKTLEKLKEELEEREKA-KKELEKLEKAL 720
|
570
....*....|....*...
gi 585420407 682 QQLEEIKHQIAKNKAIEK 699
Cdd:PRK03918 721 ERVEELREKVKKYKALLK 738
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
207-579 |
1.23e-13 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 75.87 E-value: 1.23e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 207 LEQERERLKKLLEQEKAYQARKEkenakRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQdltQKLREEEEKLK 286
Cdd:TIGR02169 676 LQRLRERLEGLKRELSSLQSELR-----RIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLK---ERLEELEEDLS 747
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 287 AITSKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNA--------KLANQESHNRQLRLKLVGLTQRIEELE-ETNKNLQK 357
Cdd:TIGR02169 748 SLEQEIENVKSELKELEARIEELEEDLHKLEEALNDlearlshsRIPEIQAELSKLEEEVSRIEARLREIEqKLNRLTLE 827
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 358 ---AEEELQELRDKIAKGECGNSSLMAEVENLRKRVLEMEgkdEEITKTESQCRELRKKLqeeehhsKELRLEVEKLQKR 434
Cdd:TIGR02169 828 keyLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELE---EELEELEAALRDLESRL-------GDLKKERDELEAQ 897
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 435 MSELEKLEEafsksksectQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLE---KAELSLKDdltklksftvmL 511
Cdd:TIGR02169 898 LRELERKIE----------ELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEeipEEELSLED-----------V 956
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 585420407 512 VDERKNMMEKIKQEErkvdglnknfkveqgkvmDVTEKLIEESKKLLKLKSEMEEKVYNLTRERDELI 579
Cdd:TIGR02169 957 QAELQRVEEEIRALE------------------PVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAIL 1006
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
154-737 |
1.40e-13 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 75.74 E-value: 1.40e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 154 LDRLEE--KQKETYRRMLEQL--------LLAEKCHRRTVYELENEKHKHTDYMNKSDDFTNLLEQERERLKKLLE---- 219
Cdd:COG1196 202 LEPLERqaEKAERYRELKEELkeleaellLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEelel 281
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 220 -----QEKAYQARKEKE--------NAKRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLK 286
Cdd:COG1196 282 eleeaQAEEYELLAELArleqdiarLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELA 361
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 287 AITSKSKEDRQKLLKLevdfEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLTQRIEELEETNKNLQKAEEELQELR 366
Cdd:COG1196 362 EAEEALLEAEAELAEA----EEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEE 437
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 367 DkiakgecgnsslmAEVENLRKRVLEMEGKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFS 446
Cdd:COG1196 438 E-------------EEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYE 504
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 447 kSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKD-DLTKLKSFTVMLVDERKNMMEKIKQE 525
Cdd:COG1196 505 -GFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDeVAAAAIEYLKAAKAGRATFLPLDKIR 583
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 526 ERKVDGLNKNFKVEQGKVMDVTEKLIEESKKllklksemeekvynLTRERDELIGKLKSEEEKSSELSCSVDLLKKRLDG 605
Cdd:COG1196 584 ARAALAAALARGAIGAAVDLVASDLREADAR--------------YYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREV 649
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 606 IEEVEREITRGRSRKGSELTcpEDNKIKELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLE 685
Cdd:COG1196 650 TLEGEGGSAGGSLTGGSRRE--LLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALE 727
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|..
gi 585420407 686 EIKHQIAKNKAIEKGEVVSQEAELRHRFRLEEAKSRDLKAEVQALKEKIHEL 737
Cdd:COG1196 728 EQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
331-790 |
2.04e-13 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 75.10 E-value: 2.04e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 331 NRQLRLKLVGLTQRIEELEETNKNLQKAEEELQELRDKIAKgecgnssLMAEVENLRKRVLEMEgkdEEITKTESQCREL 410
Cdd:PRK03918 143 SDESREKVVRQILGLDDYENAYKNLGEVIKEIKRRIERLEK-------FIKRTENIEELIKEKE---KELEEVLREINEI 212
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 411 RKKLqeeehhsKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRL 490
Cdd:PRK03918 213 SSEL-------PELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKEL 285
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 491 EKAElSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVtEKLIEESKKLLKLKSEMEEKVYN 570
Cdd:PRK03918 286 KELK-EKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERL-EELKKKLKELEKRLEELEERHEL 363
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 571 LTRERdeligklkseeekssELSCSVDLLKKRLDG--IEEVEREITRGRSRKgseltcpednkiKELTLEIERLKKRLQQ 648
Cdd:PRK03918 364 YEEAK---------------AKKEELERLKKRLTGltPEKLEKELEELEKAK------------EEIEEEISKITARIGE 416
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 649 LEVVEGDLMKTEDEYDQLEQKFR------TEQDKANFLSQQLEEIkhqiaKNKAIEKGEVVSQEAELRHRFRlEEAKSRD 722
Cdd:PRK03918 417 LKKEIKELKKAIEELKKAKGKCPvcgrelTEEHRKELLEEYTAEL-----KRIEKELKEIEEKERKLRKELR-ELEKVLK 490
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 585420407 723 LKAEVQALKEKIHELMNKEDQLSQLQV-DYSVLQQRFMEEENKNKNMGQEVLNLTKELELSKRYSRALR 790
Cdd:PRK03918 491 KESELIKLKELAEQLKELEEKLKKYNLeELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLA 559
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
341-796 |
4.70e-13 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 73.65 E-value: 4.70e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 341 LTQRIEELEETNKNLQKAEEELQELRDKIAKgecgnssLMAEVENLRKRVLEMEgKDEEITKTESQCRELRKKLQEEEHH 420
Cdd:COG4717 76 LEEELKEAEEKEEEYAELQEELEELEEELEE-------LEAELEELREELEKLE-KLLQLLPLYQELEALEAELAELPER 147
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 421 SKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQL--HLNLEKEKNLtKDLLNELEVVKSRVKELecsESRLEKAELSLK 498
Cdd:COG4717 148 LEELEERLEELRELEEELEELEAELAELQEELEELleQLSLATEEEL-QDLAEELEELQQRLAEL---EEELEEAQEELE 223
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 499 DDLTKLKSFTVMLVDERKNmmEKIKQEERK------------VDGLNKNFKVEQGKVMDVTEKLI-----EESKKLLKLK 561
Cdd:COG4717 224 ELEEELEQLENELEAAALE--ERLKEARLLlliaaallallgLGGSLLSLILTIAGVLFLVLGLLallflLLAREKASLG 301
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 562 SEMEEKVYNLTRERDELIGKLKSEEEKSSELSCSVDLLKKRLDGIEEVEREITRGRSRkgseltcpednkikELTLEIER 641
Cdd:COG4717 302 KEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEEL--------------EEELQLEE 367
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 642 LKKRLQQLevVEGDLMKTEDEYDQLEQKFRTEQDkanfLSQQLEEIKHQI-AKNKAIEKGEVVSQEAELRHRFRLEEAKS 720
Cdd:COG4717 368 LEQEIAAL--LAEAGVEDEEELRAALEQAEEYQE----LKEELEELEEQLeELLGELEELLEALDEEELEEELEELEEEL 441
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 721 RDLKAEVQALKEKIHELmnkEDQLSQLQVD--YSVLQQRFMEEENKNKNMGQE--VLNLTKEL--ELSKRYSRALRPSVN 794
Cdd:COG4717 442 EELEEELEELREELAEL---EAELEQLEEDgeLAELLQELEELKAELRELAEEwaALKLALELleEAREEYREERLPPVL 518
|
..
gi 585420407 795 GR 796
Cdd:COG4717 519 ER 520
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
152-788 |
5.06e-13 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 73.94 E-value: 5.06e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 152 SELDRLEEKQKETYRRMLE-QLLLAEkcHRRTVYELENEKHKHT----DYMNKSDDFTNLLEQERERLKKLLEQEKAYQA 226
Cdd:TIGR02168 246 EELKEAEEELEELTAELQElEEKLEE--LRLEVSELEEEIEELQkelyALANEISRLEQQKQILRERLANLERQLEELEA 323
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 227 RKEkENAKRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAITSKSKEDRQKLLKLEVDF 306
Cdd:TIGR02168 324 QLE-ELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEI 402
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 307 ----------EHKASRFSQEHEEMNAKLANQESHNRQLRLKLV--GLTQRIEELEETNKNLQKAEEELQELRDKIAKGEC 374
Cdd:TIGR02168 403 erlearlerlEDRRERLQQEIEELLKKLEEAELKELQAELEELeeELEELQEELERLEEALEELREELEEAEQALDAAER 482
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 375 GNSSLMAEVENLRKRVLEMEGKDE---EITKTESQCRELRKKLQEEEHHSKELRLEVEK-LQKRMSEL--EKLEEAFS-- 446
Cdd:TIGR02168 483 ELAQLQARLDSLERLQENLEGFSEgvkALLKNQSGLSGILGVLSELISVDEGYEAAIEAaLGGRLQAVvvENLNAAKKai 562
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 447 -----KSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELecseSRLEKAELSLKDDLTKLKSfTVMLVDERKNMMEK 521
Cdd:TIGR02168 563 aflkqNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVA----KDLVKFDPKLRKALSYLLG-GVLVVDDLDNALEL 637
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 522 IKQE----------------------------------ERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEK 567
Cdd:TIGR02168 638 AKKLrpgyrivtldgdlvrpggvitggsaktnssilerRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQL 717
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 568 VYNLTRERDELIGKLKSEEEKSSELSCSVDLLKKRLDGIEEVEREITRGRSRKGSELTCPE--DNKIKELTLEIERLKKR 645
Cdd:TIGR02168 718 RKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAeaEAEIEELEAQIEQLKEE 797
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 646 LQQLE----VVEGDLMKTEDEYDQLEQKFRTEQDK-------ANFLSQQLEEIKHQIAKNKA------------------ 696
Cdd:TIGR02168 798 LKALRealdELRAELTLLNEEAANLRERLESLERRiaaterrLEDLEEQIEELSEDIESLAAeieeleelieeleselea 877
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 697 --IEKGEVVSQEAELRHRFRLEEAKSRDLKAEVQALKEKIHELMNK----EDQLSQLQVDYSVLQQRFMEEENKNknmGQ 770
Cdd:TIGR02168 878 llNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKlaqlELRLEGLEVRIDNLQERLSEEYSLT---LE 954
|
730
....*....|....*...
gi 585420407 771 EVLNLTKELELSKRYSRA 788
Cdd:TIGR02168 955 EAEALENKIEDDEEEARR 972
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
254-567 |
7.38e-13 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 73.56 E-value: 7.38e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 254 VDERQMHIEQLGLQSQKVQdltqKLREEEEKLKAITSKSKEDRQKLLKLEVDfEHKASRfsqehEEMNAKLANQESHNRQ 333
Cdd:TIGR02169 186 IERLDLIIDEKRQQLERLR----REREKAERYQALLKEKREYEGYELLKEKE-ALERQK-----EAIERQLASLEEELEK 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 334 LRLKLVGLTQRIEELEETNKNLQK-----AEEELQELRDKIAKGECGNSSLMAEVENLRKRVLEMEGK----DEEITKTE 404
Cdd:TIGR02169 256 LTEEISELEKRLEEIEQLLEELNKkikdlGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERlaklEAEIDKLL 335
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 405 SQCRELRKKLQEEEHHSKELRLEVEKLQKRM----SELEKLEEAFSKSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRV 480
Cdd:TIGR02169 336 AEIEELEREIEEERKRRDKLTEEYAELKEELedlrAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEEL 415
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 481 KELECSESRLEKAELSLKDDLTKLKSftvmlvdERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKL 560
Cdd:TIGR02169 416 QRLSEELADLNAAIAGIEAKINELEE-------EKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKL 488
|
....*..
gi 585420407 561 KSEMEEK 567
Cdd:TIGR02169 489 QRELAEA 495
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
216-780 |
4.72e-12 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 70.43 E-value: 4.72e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 216 KLLEQEKAYQARKEKENAKRLNKLRDELVKLKSfaLMLVDERQMH-----IEQLGLQSQKVQDLTQKLREEEEKLKAITS 290
Cdd:TIGR04523 78 KILEQQIKDLNDKLKKNKDKINKLNSDLSKINS--EIKNDKEQKNkleveLNKLEKQKKENKKNIDKFLTEIKKKEKELE 155
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 291 KSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVgltqrieeleetnkNLQKAEEELQELRDKIA 370
Cdd:TIGR04523 156 KLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLS--------------NLKKKIQKNKSLESQIS 221
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 371 KGECGNSSLMAEVENLRKrvlEMEGKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLeeaFSKSKS 450
Cdd:TIGR04523 222 ELKKQNNQLKDNIEKKQQ---EINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQ---LNQLKS 295
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 451 ECtqLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVD 530
Cdd:TIGR04523 296 EI--SDLNNQKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIE 373
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 531 GLNKNfkveqgkvmdvTEKLIEESKKLLKLKSEMEEKVYNLTRERDELIGKLKSEEEKSSELSCSVDLLKKRldgIEEVE 610
Cdd:TIGR04523 374 KLKKE-----------NQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKET---IIKNN 439
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 611 REItrgrsrkgSELTcpedNKIKELTLEIERLKKRL----QQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEE 686
Cdd:TIGR04523 440 SEI--------KDLT----NQDSVKELIIKNLDNTResleTQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKE 507
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 687 IKHQIaKNKAIEKGEVVSQEAELRHRFRLEEAKSRDLKAEVQALKEKIH------ELMNKEDQLSQLQVDYSVLQQRFME 760
Cdd:TIGR04523 508 LEEKV-KDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKkenlekEIDEKNKEIEELKQTQKSLKKKQEE 586
|
570 580
....*....|....*....|
gi 585420407 761 EENKNKNMGQEVLNLTKELE 780
Cdd:TIGR04523 587 KQELIDQKEKEKKDLIKEIE 606
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
346-693 |
5.14e-12 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 70.48 E-value: 5.14e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 346 EELEETNKNLQKAEEELQELRDKIAKGECGNSSLMAEVENLRKRVLEMEGKDEEITKTESQCRELRKKLQEEEHHSKELR 425
Cdd:TIGR02169 674 AELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEI 753
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 426 LEVE-KLQKRMSELEKLEEAFSKSKSECTQLHLNLEKEKnlTKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKL 504
Cdd:TIGR02169 754 ENVKsELKELEARIEELEEDLHKLEEALNDLEARLSHSR--IPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYL 831
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 505 KSFTVMLVDERKNMMEKIKQEERKVDGLNKNFkveqgkvmdvtEKLIEESKKLLKLKSEMEEKVYNLTRERDELIGKLKS 584
Cdd:TIGR02169 832 EKEIQELQEQRIDLKEQIKSIEKEIENLNGKK-----------EELEEELEELEAALRDLESRLGDLKKERDELEAQLRE 900
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 585 EEEKSSELSCSVDLLKKRLD----GIEEVEREITR-GRSRKGSELTCPEDNKIKELTLEIERLKKRLQQLEVVEgdlMKT 659
Cdd:TIGR02169 901 LERKIEELEAQIEKKRKRLSelkaKLEALEEELSEiEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRALEPVN---MLA 977
|
330 340 350
....*....|....*....|....*....|....
gi 585420407 660 EDEYDQLEQKFRTEQDKANFLSQQLEEIKHQIAK 693
Cdd:TIGR02169 978 IQEYEEVLKRLDELKEKRAKLEEERKAILERIEE 1011
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
152-504 |
3.44e-11 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 68.16 E-value: 3.44e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 152 SELDRLEEKQKEtyrrMLEQLLLAEKchrrtvyELENEKHKHTDYMNKSDDFTNLLEQERERLKKLLEQEKAYQARKEKE 231
Cdd:TIGR02168 677 REIEELEEKIEE----LEEKIAELEK-------ALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQL 745
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 232 nAKRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAITSKSKEDRQKLLKLEVDFEHKAS 311
Cdd:TIGR02168 746 -EERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRE 824
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 312 RFSQEHEEMNAKLANQESHNRQLRLKLVGLTQRIEELEETNKNLQKAEEELQELRDKIAKGECGNSSLMAEVENLRKRVL 391
Cdd:TIGR02168 825 RLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELR 904
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 392 EMEgkdEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAF-----SKSKSECTQLHLNLEKEKNLT 466
Cdd:TIGR02168 905 ELE---SKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEaealeNKIEDDEEEARRRLKRLENKI 981
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 585420407 467 KDL-------LNELEVVKSRVKELECSESRLEKAELSLKDDLTKL 504
Cdd:TIGR02168 982 KELgpvnlaaIEEYEELKERYDFLTAQKEDLTEAKETLEEAIEEI 1026
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
197-484 |
3.88e-11 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 67.77 E-value: 3.88e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 197 MNKSDDFTNLLEQERERLKKLLEQEKAYQARKEKENAKRLNKLRDEL---------------------VKLKSFALMLVD 255
Cdd:TIGR02168 661 ITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELeeleeeleqlrkeleelsrqiSALRKDLARLEA 740
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 256 ERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAITSKSKEDRQKLLKLEVDFEHKASRFSQ----------EHEEMNAKLA 325
Cdd:TIGR02168 741 EVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKAlrealdelraELTLLNEEAA 820
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 326 NQESHNRQLRLKLVGLTQRIEELEETNKNLQKAE-------EELQELRDKIAKGECGNSSLMAEVE-NLRKRVLEMEGKD 397
Cdd:TIGR02168 821 NLRERLESLERRIAATERRLEDLEEQIEELSEDIeslaaeiEELEELIEELESELEALLNERASLEeALALLRSELEELS 900
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 398 EEITKTESQCRELRKKLQEEEHHSKELRLEVEKL-QKRMSELEKLEEAFSksksectqlhLNLEKEKNLTKDLLNELEVV 476
Cdd:TIGR02168 901 EELRELESKRSELRRELEELREKLAQLELRLEGLeVRIDNLQERLSEEYS----------LTLEEAEALENKIEDDEEEA 970
|
....*...
gi 585420407 477 KSRVKELE 484
Cdd:TIGR02168 971 RRRLKRLE 978
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
30-555 |
4.10e-11 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 67.86 E-value: 4.10e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 30 AGEKSLSEDAKKKKKSNRKEDDvmasgtvkrhLKTSGECERKTKKSLELSKEDLIQLLSIMEGELQAREDvihmlKTEKT 109
Cdd:PTZ00121 1298 AEEKKKADEAKKKAEEAKKADE----------AKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAAD-----EAEAA 1362
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 110 KPEVLEAHYGSAEPEKVLRVLHRDAilaQEKSIGEDVYEKPISELDRLEE-KQKETYRRMLEQLLLAEKCHRRTvyeleN 188
Cdd:PTZ00121 1363 EEKAEAAEKKKEEAKKKADAAKKKA---EEKKKADEAKKKAEEDKKKADElKKAAAAKKKADEAKKKAEEKKKA-----D 1434
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 189 EKHKHTDYMNKSDDFTNLLEQER---ERLKKLLEQEKAYQARKEKENAKRLNKLRD--ELVKLKSFALMLVDERQMHIEQ 263
Cdd:PTZ00121 1435 EAKKKAEEAKKADEAKKKAEEAKkaeEAKKKAEEAKKADEAKKKAEEAKKADEAKKkaEEAKKKADEAKKAAEAKKKADE 1514
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 264 LGLQSQKVQdlTQKLREEEEKLKAITSKSKEDRQKLLKLEvdfehKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLTQ 343
Cdd:PTZ00121 1515 AKKAEEAKK--ADEAKKAEEAKKADEAKKAEEKKKADELK-----KAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAK 1587
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 344 RIEE--LEETNKNLQ-----KAEEELQELRDKIAKGECGNSS-LMAEVENLRKRVLEMEGKDEEITKTESQCR----ELR 411
Cdd:PTZ00121 1588 KAEEarIEEVMKLYEeekkmKAEEAKKAEEAKIKAEELKKAEeEKKKVEQLKKKEAEEKKKAEELKKAEEENKikaaEEA 1667
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 412 KKLQEEEHHSKELRLEVEKLQKRMSELEKLEEafskSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELEC-SESRL 490
Cdd:PTZ00121 1668 KKAEEDKKKAEEAKKAEEDEKKAAEALKKEAE----EAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKeAEEDK 1743
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 585420407 491 EKAELSLKDDLTKLKsfTVMLVDERKNMMEKIKQEERKVdgLNKNFKVEQGKVMDVTEKLIEESK 555
Cdd:PTZ00121 1744 KKAEEAKKDEEEKKK--IAHLKKEEEKKAEEIRKEKEAV--IEEELDEEDEKRRMEVDKKIKDIF 1804
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
155-806 |
2.77e-10 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 65.14 E-value: 2.77e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 155 DRLEEKQKETYRRMleQLLLAEKCHR--RTVYELENEKHKHTDYMNKSDDFTNLLEQERERLKKLLEQEKAYQARKEKEN 232
Cdd:pfam15921 245 DQLEALKSESQNKI--ELLLQQHQDRieQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDL 322
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 233 AKRLNKLRDELVKLKSfalMLVDErqmhIEQLGLQSQKVQDLTQKLREEEEKLKAITSKSKEDRQKLLkleVDFEHKASR 312
Cdd:pfam15921 323 ESTVSQLRSELREAKR---MYEDK----IEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLL---ADLHKREKE 392
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 313 FSQEHEEmNAKLANQESHNR----QLRLKLVGLTQRIEELEETNKNLQ-----KAEEELQELRDKIAKGEcGNSSLMAEV 383
Cdd:pfam15921 393 LSLEKEQ-NKRLWDRDTGNSitidHLRRELDDRNMEVQRLEALLKAMKsecqgQMERQMAAIQGKNESLE-KVSSLTAQL 470
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 384 EN----LRKRVLEMEGKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKR----MSELEKL---EEAFSKSKSEC 452
Cdd:pfam15921 471 EStkemLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRvdlkLQELQHLkneGDHLRNVQTEC 550
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 453 TQLHLNLEKEKNLTKDLLNELEVVKSRVKE--LECSESRLEKAEL--SLKDDLTKLKSFTVMlvDERKNmmEKIKQEERK 528
Cdd:pfam15921 551 EALKLQMAEKDKVIEILRQQIENMTQLVGQhgRTAGAMQVEKAQLekEINDRRLELQEFKIL--KDKKD--AKIRELEAR 626
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 529 VDGLNKnfkveqgkvmdvteklieESKKLLKLKSEMEEKVYNLTRERDELIGKLKSEEEKSSELSCSVDLLKKRLdgiee 608
Cdd:pfam15921 627 VSDLEL------------------EKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNF----- 683
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 609 vereitRGRSRKGSELTCPEDNKIKELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEEIK 688
Cdd:pfam15921 684 ------RNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAM 757
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 689 HQIAKNKAIEKGE--VVSQEAELRHRFRLEEAKSRD-LKAEVQALKEKIhelMNKEDQLSQLQVDYSVLQQRFMEEENKN 765
Cdd:pfam15921 758 TNANKEKHFLKEEknKLSQELSTVATEKNKMAGELEvLRSQERRLKEKV---ANMEVALDKASLQFAECQDIIQRQEQES 834
|
650 660 670 680
....*....|....*....|....*....|....*....|....*..
gi 585420407 766 KNMGQEVLNLTKELE------LSKRYSRALRPSVNGRRMVDVPVTST 806
Cdd:pfam15921 835 VRLKLQHTLDVKELQgpgytsNSSMKPRLLQPASFTRTHSNVPSSQS 881
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
317-714 |
3.42e-10 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 64.69 E-value: 3.42e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 317 HEEMNAKLANQESHNRQLRLKLVGLTQRIEELE-----------ETNKNLQKAEEELQELRDKIAKGECGNSSLMAEVEN 385
Cdd:TIGR02168 665 SAKTNSSILERRREIEELEEKIEELEEKIAELEkalaelrkeleELEEELEQLRKELEELSRQISALRKDLARLEAEVEQ 744
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 386 LRKRV----LEMEGKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRM----SELEKLEEAFSKSKSECTQLHL 457
Cdd:TIGR02168 745 LEERIaqlsKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELkalrEALDELRAELTLLNEEAANLRE 824
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 458 NLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFK 537
Cdd:TIGR02168 825 RLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELR 904
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 538 VEQGKVMDVTEKLIEESKKLLKLKSEMEEkvynLTRERDELIGKLKSEEEKSselscsvdllkkrLDGIEEVEREItrgr 617
Cdd:TIGR02168 905 ELESKRSELRRELEELREKLAQLELRLEG----LEVRIDNLQERLSEEYSLT-------------LEEAEALENKI---- 963
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 618 srkgseltcpeDNKIKELTLEIERLKKRLQQLEVVEgdlMKTEDEYDQLEQKFRteqdkanFLSQQLEEIkhqiakNKAI 697
Cdd:TIGR02168 964 -----------EDDEEEARRRLKRLENKIKELGPVN---LAAIEEYEELKERYD-------FLTAQKEDL------TEAK 1016
|
410
....*....|....*....
gi 585420407 698 EKGEVVSQE--AELRHRFR 714
Cdd:TIGR02168 1017 ETLEEAIEEidREARERFK 1035
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
152-779 |
4.68e-10 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 63.89 E-value: 4.68e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 152 SELDRLEEKQKETyrrmleqlllaEKCHRRTVYELENeKHKHTDYMNKSDDFTNLLEQERERLKKLLEQEKAyqarkEKE 231
Cdd:TIGR04523 124 VELNKLEKQKKEN-----------KKNIDKFLTEIKK-KEKELEKLNNKYNDLKKQKEELENELNLLEKEKL-----NIQ 186
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 232 NAkrLNKLRDELVKLKSFALMLVDERQMH------IEQLGLQSQKVQDLTQKLREEEEKLKAITSKSKEDRQKLLKLEVD 305
Cdd:TIGR04523 187 KN--IDKIKNKLLKLELLLSNLKKKIQKNkslesqISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNK 264
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 306 FEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLTQRIEE--LEETNKNLQKAEEELQELRDKIAKGECGNSSLMAEV 383
Cdd:TIGR04523 265 IKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQdwNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQI 344
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 384 ENLRKrvlemegkdeEITKTESQCRELRKKLQEEEhhsKELRLEVEKLQKRMSELEKLEeafskskSECTQLHLNLEKEK 463
Cdd:TIGR04523 345 SQLKK----------ELTNSESENSEKQRELEEKQ---NEIEKLKKENQSYKQEIKNLE-------SQINDLESKIQNQE 404
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 464 NLTKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKV 543
Cdd:TIGR04523 405 KLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNL 484
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 544 MDVTEKLIEESKKLLKL---KSEMEEKVYNLTRERDELIgklkseeeksselscsvdllkkrldgieevereitrgrsrk 620
Cdd:TIGR04523 485 EQKQKELKSKEKELKKLneeKKELEEKVKDLTKKISSLK----------------------------------------- 523
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 621 gseltcpedNKIKELTLEIERLKKRLQQLEVvEGDLMKTEDEYDQLEqkfrTEQDKANflsQQLEEIKHQiakNKAIEKg 700
Cdd:TIGR04523 524 ---------EKIEKLESEKKEKESKISDLED-ELNKDDFELKKENLE----KEIDEKN---KEIEELKQT---QKSLKK- 582
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 585420407 701 evvSQEaELRHRFRLEEAKSRDLKAEVQALKEKIHELmnkEDQLSQLQVDYSVLQQRFMEEENKNKNMGQEVLNLTKEL 779
Cdd:TIGR04523 583 ---KQE-EKQELIDQKEKEKKDLIKEIEEKEKKISSL---EKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETI 654
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
184-783 |
4.83e-10 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 64.22 E-value: 4.83e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 184 YELENEKHKHTDYMNKSDDFTNLLEQERERLKKlleqekayQARKEKENAKRLNKLRDELVKLKsfalmLVDERQMHIEQ 263
Cdd:pfam02463 172 KEALKKLIEETENLAELIIDLEELKLQELKLKE--------QAKKALEYYQLKEKLELEEEYLL-----YLDYLKLNEER 238
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 264 LglqsQKVQDLTQKLREEEEKLKAITSKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLTQ 343
Cdd:pfam02463 239 I----DLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEE 314
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 344 RIEELEETNKNLQKAEEELQElrdkiakgecgnsslmaEVENLRKRVLEMEGKDEEITKTESQCRELRKKL-QEEEHHSK 422
Cdd:pfam02463 315 KLKESEKEKKKAEKELKKEKE-----------------EIEELEKELKELEIKREAEEEEEEELEKLQEKLeQLEEELLA 377
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 423 ELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLEKEKNLTKDLLN-ELEVVKSRVKELECSESRLEKAELSLKDDL 501
Cdd:pfam02463 378 KKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKeELEILEEEEESIELKQGKLTEEKEELEKQE 457
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 502 TKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLiEESKKLLKLKSEMEEKVYNLTRERDELIGK 581
Cdd:pfam02463 458 LKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKAR-SGLKVLLALIKDGVGGRIISAHGRLGDLGV 536
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 582 LKSEEEKSSELSCSVDLLKKRLDGIEEVEREITRGRSRKGSELTCPEDNKIKEltleierLKKRLQQLEVVEGDLMKTED 661
Cdd:pfam02463 537 AVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKL-------PLKSIAVLEIDPILNLAQLD 609
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 662 EYDQLEQKFRTEQDKANFLSQQLEEIKHQIAKNKAIEKGEVVSQEAEL---RHRFRLEEAKSRDLKAEVQALKEKIHELM 738
Cdd:pfam02463 610 KATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGlaeKSEVKASLSELTKELLEIQELQEKAESEL 689
|
570 580 590 600
....*....|....*....|....*....|....*....|....*
gi 585420407 739 NKEDQLSQLQvDYSVLQQRFMEEENKNKNMGQEVLNLTKELELSK 783
Cdd:pfam02463 690 AKEEILRRQL-EIKKKEQREKEELKKLKLEAEELLADRVQEAQDK 733
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
381-737 |
6.03e-10 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 63.92 E-value: 6.03e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 381 AEVENLRKRVLEMEGKDEEITKtesQCRELRKKLQeeehhskELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLE 460
Cdd:TIGR02168 677 REIEELEEKIEELEEKIAELEK---ALAELRKELE-------ELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLE 746
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 461 KEKNLTKDLLNELEVvksrvkELECSESRLEKAELSLKDDLTKLKSftvmLVDERKNMMEKIKQEERKVDGLNKNFKVEQ 540
Cdd:TIGR02168 747 ERIAQLSKELTELEA------EIEELEERLEEAEEELAEAEAEIEE----LEAQIEQLKEELKALREALDELRAELTLLN 816
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 541 GKVMDVTEKLIEESKKLLKLKSEMEEKVYNLTRERDELIGklkseeeksselscsvdlLKKRLDGIEEVEREITRGRsrk 620
Cdd:TIGR02168 817 EEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIES------------------LAAEIEELEELIEELESEL--- 875
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 621 gseltcpeDNKIKELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQIAKNKAI--E 698
Cdd:TIGR02168 876 --------EALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERlsE 947
|
330 340 350
....*....|....*....|....*....|....*....
gi 585420407 699 KGEVVSQEAELRHRFRleEAKSRDLKAEVQALKEKIHEL 737
Cdd:TIGR02168 948 EYSLTLEEAEALENKI--EDDEEEARRRLKRLENKIKEL 984
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
131-790 |
2.32e-09 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 61.66 E-value: 2.32e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 131 HRDAILAQEKSIGEDVYEKPISELdRLEEKQKETYRRMLEQL-------LLAEKCHRR----TVYELENEKHKHTdYMNK 199
Cdd:pfam05483 111 NRKIIEAQRKAIQELQFENEKVSL-KLEEEIQENKDLIKENNatrhlcnLLKETCARSaektKKYEYEREETRQV-YMDL 188
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 200 SDDFTNLLeQERERLKKLLEQEKAYQARKEKENAKRLNKLRDELVKLksfalmlVDERQMHIEQLGLQS----QKVQDLT 275
Cdd:pfam05483 189 NNNIEKMI-LAFEELRVQAENARLEMHFKLKEDHEKIQHLEEEYKKE-------INDKEKQVSLLLIQItekeNKMKDLT 260
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 276 QKLREEEEKLKAITSKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLTQRIEELEETNKNL 355
Cdd:pfam05483 261 FLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQMEEL 340
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 356 QKAEEELQELRDKIAKGECGNSSLM-AEVENLRKRVLEMEGKDEEITKTESQCRELRKKLQEEEHHSKELRL---EVEKL 431
Cdd:pfam05483 341 NKAKAAHSFVVTEFEATTCSLEELLrTEQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELKKilaEDEKL 420
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 432 QKRMSELEKLEEAFSKSKSECTQLHLNLEKEknlTKDLLNELEVVKSR----VKELECSESRLEKAEL---SLKDDLTKL 504
Cdd:pfam05483 421 LDEKKQFEKIAEELKGKEQELIFLLQAREKE---IHDLEIQLTAIKTSeehyLKEVEDLKTELEKEKLkniELTAHCDKL 497
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 505 KSFTVMLVDERKNMMEKIKQEERKVDglnkNFKVEQGKVMDVTEKLIEeskKLLKLKSEMEEKVYNLTRERDELIGKLKS 584
Cdd:pfam05483 498 LLENKELTQEASDMTLELKKHQEDII----NCKKQEERMLKQIENLEE---KEMNLRDELESVREEFIQKGDEVKCKLDK 570
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 585 EEEKSSELSCSVDLLKKRLDGIEEVEREITRGRSRKgseltcpeDNKIKELTLEIERLKKR----LQQLEVVEGDLMKTE 660
Cdd:pfam05483 571 SEENARSIEYEVLKKEKQMKILENKCNNLKKQIENK--------NKNIEELHQENKALKKKgsaeNKQLNAYEIKVNKLE 642
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 661 DEYDQLEQKF----RTEQDKANFLSQQLEEIKHQIAKNKAIEKGEV-VSQEAELRHRFRLeeaksrdlkAEVQALKEKIH 735
Cdd:pfam05483 643 LELASAKQKFeeiiDNYQKEIEDKKISEEKLLEEVEKAKAIADEAVkLQKEIDKRCQHKI---------AEMVALMEKHK 713
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 736 ELMNK--EDQLSQLQVDYSVLQQRFMEE---ENKNKNMGQEVLNLTKELELSKRYSRALR 790
Cdd:pfam05483 714 HQYDKiiEERDSELGLYKNKEQEQSSAKaalEIELSNIKAELLSLKKQLEIEKEEKEKLK 773
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
348-688 |
3.42e-09 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 61.61 E-value: 3.42e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 348 LEETNKNLQKAEEELQELRDKI----AKGECGNS--SLMAEVENLRKRVL---------EMEGKDEEITKTESQCRELRK 412
Cdd:TIGR02168 181 LERTRENLDRLEDILNELERQLksleRQAEKAERykELKAELRELELALLvlrleelreELEELQEELKEAEEELEELTA 260
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 413 KLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSEctqlhlnLEKEKNLTKDllnELEVVKSRVKELECSESRLEK 492
Cdd:TIGR02168 261 ELQELEEKLEELRLEVSELEEEIEELQKELYALANEISR-------LEQQKQILRE---RLANLERQLEELEAQLEELES 330
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 493 AELSLKDDLTKLKsftvmlvderknmmEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYNLT 572
Cdd:TIGR02168 331 KLDELAEELAELE--------------EKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIA 396
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 573 RERDELIgklkseeeksselscsvdLLKKRLdgiEEVEREITRGRSRKGSELTCPEDNKIKELTLEIERLKKRL----QQ 648
Cdd:TIGR02168 397 SLNNEIE------------------RLEARL---ERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELeelqEE 455
|
330 340 350 360
....*....|....*....|....*....|....*....|
gi 585420407 649 LEVVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEEIK 688
Cdd:TIGR02168 456 LERLEEALEELREELEEAEQALDAAERELAQLQARLDSLE 495
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
156-778 |
4.39e-09 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 61.22 E-value: 4.39e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 156 RLEEKQKETYRRMLEQLLLAEKCHRRTVYELENEKHKHTDYMNKSDDFTNLLEQERERL-----KKLLEQEKAYQARKEK 230
Cdd:TIGR00606 287 ELELKMEKVFQGTDEQLNDLYHNHQRTVREKERELVDCQRELEKLNKERRLLNQEKTELlveqgRLQLQADRHQEHIRAR 366
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 231 ENAKRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAITSKSKEDRQKLLKLEVDFEHKA 310
Cdd:TIGR00606 367 DSLIQSLATRLELDGFERGPFSERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKK 446
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 311 SRFSQEHEEMNAK---LANQESHNRQLRLKLVGLTQRIEELEETNKN-----LQKAEEELQELRDKIAKGECGNSSLMAE 382
Cdd:TIGR00606 447 EILEKKQEELKFVikeLQQLEGSSDRILELDQELRKAERELSKAEKNsltetLKKEVKSLQNEKADLDRKLRKLDQEMEQ 526
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 383 VENLRKRVLEMEG-------KDEEITKTESQ--------------CRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKL 441
Cdd:TIGR00606 527 LNHHTTTRTQMEMltkdkmdKDEQIRKIKSRhsdeltsllgyfpnKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQN 606
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 442 EEAFSKSKSECTQLHLNLEK---EKNLTKDLLNELEVVKSRVKelecsESRLEKAELSLKDDLtkLKSFTVMLVDERKNM 518
Cdd:TIGR00606 607 KNHINNELESKEEQLSSYEDklfDVCGSQDEESDLERLKEEIE-----KSSKQRAMLAGATAV--YSQFITQLTDENQSC 679
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 519 MEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLiEESKKLLKLKSEMEEKVYNLTRERDELIGKLKSEEEKSSELSCSVDL 598
Cdd:TIGR00606 680 CPVCQRVFQTEAELQEFISDLQSKLRLAPDKL-KSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNR 758
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 599 LKKRL-DGIEEVEREITRGRSRKGSELTCPEDNKIKE-LTLEIERLKKRLQQLeVVEGDLMKTEDEYDQLEQKFRTEQDK 676
Cdd:TIGR00606 759 DIQRLkNDIEEQETLLGTIMPEEESAKVCLTDVTIMErFQMELKDVERKIAQQ-AAKLQGSDLDRTVQQVNQEKQEKQHE 837
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 677 ANFLSQQLEEIKHQIA-KNKAIE---------KGEVVSQEAELRHRFRLEEaKSRDLKAEVQALKEKIHELMNKEDQLSQ 746
Cdd:TIGR00606 838 LDTVVSKIELNRKLIQdQQEQIQhlksktnelKSEKLQIGTNLQRRQQFEE-QLVELSTEVQSLIREIKDAKEQDSPLET 916
|
650 660 670
....*....|....*....|....*....|..
gi 585420407 747 LQVDYSVLQQRFMEEENKNKNMGQEVLNLTKE 778
Cdd:TIGR00606 917 FLEKDQQEKEELISSKETSNKKAQDKVNDIKE 948
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
124-751 |
5.18e-09 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 60.70 E-value: 5.18e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 124 EKVLRVLHRDAILAQEKSIGEDVY----EKP--ISELDRLEEkQKETYRRMLEQLLLAEKCHRRtvyeLENEKHKHTDYM 197
Cdd:COG4913 191 EKALRLLHKTQSFKPIGDLDDFVReymlEEPdtFEAADALVE-HFDDLERAHEALEDAREQIEL----LEPIRELAERYA 265
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 198 NKSDDFtNLLEQERERLKKLLEQEKAYQARKEKENAKR-LNKLRDELVKLKS-FALMLVDERQMHIEQLGLQSQKVQDLT 275
Cdd:COG4913 266 AARERL-AELEYLRAALRLWFAQRRLELLEAELEELRAeLARLEAELERLEArLDALREELDELEAQIRGNGGDRLEQLE 344
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 276 QKLREEEEKLKAITSKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRlklvgltqriEELEETNKNL 355
Cdd:COG4913 345 REIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALE----------EALAEAEAAL 414
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 356 QKAEEELQELRDKIAKGECGNSSLMAEVENLRKRVLemegkdEEITKTESQCR---ELRKKLQEEEH---------HSKE 423
Cdd:COG4913 415 RDLRRELRELEAEIASLERRKSNIPARLLALRDALA------EALGLDEAELPfvgELIEVRPEEERwrgaiervlGGFA 488
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 424 LRLEVEklqkrmselEKLEEAFSKS-KSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLE---KAELSlkd 499
Cdd:COG4913 489 LTLLVP---------PEHYAAALRWvNRLHLRGRLVYERVRTGLPDPERPRLDPDSLAGKLDFKPHPFRawlEAELG--- 556
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 500 dltklKSFTVMLVDERknmmEKIKQEERKV--DGL----------NKNFKVEQGKVM--DVTEKLIEESKKLLKLKSEME 565
Cdd:COG4913 557 -----RRFDYVCVDSP----EELRRHPRAItrAGQvkgngtrhekDDRRRIRSRYVLgfDNRAKLAALEAELAELEEELA 627
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 566 EkvynLTRERDELIGKLKSEEEKSSELSCSVDLLKKRLDgIEEVEREITRGRSRKGSELTcpEDNKIKELTLEIERLKKR 645
Cdd:COG4913 628 E----AEERLEALEAELDALQERREALQRLAEYSWDEID-VASAEREIAELEAELERLDA--SSDDLAALEEQLEELEAE 700
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 646 LQQLevvegdlmktEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQIAknkAIEKGEVVSQEAELRHRF------RLEEAK 719
Cdd:COG4913 701 LEEL----------EEELDELKGEIGRLEKELEQAEEELDELQDRLE---AAEDLARLELRALLEERFaaalgdAVEREL 767
|
650 660 670
....*....|....*....|....*....|..
gi 585420407 720 SRDLKAEVQALKEKIHelmNKEDQLSQLQVDY 751
Cdd:COG4913 768 RENLEERIDALRARLN---RAEEELERAMRAF 796
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
206-744 |
8.49e-09 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 60.05 E-value: 8.49e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 206 LLEQERERLKKLLEQekaYQARKEKENAKRLNKLRDELvklksfalmlvDERQMHIEQlgLQSQKVQdltqkLREEEEKL 285
Cdd:PRK02224 181 VLSDQRGSLDQLKAQ---IEEKEEKDLHERLNGLESEL-----------AELDEEIER--YEEQREQ-----ARETRDEA 239
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 286 KAITSKSKEDRQKLLKLEvdfehkasrfsQEHEEMNAKLANQESHNRQLRLKLVGLTQRIEELeetnknlqkaEEELQEL 365
Cdd:PRK02224 240 DEVLEEHEERREELETLE-----------AEIEDLRETIAETEREREELAEEVRDLRERLEEL----------EEERDDL 298
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 366 RDKIAKGECGNSSLMAEVENLRKRVLEMEGKDEE----ITKTESQCRELRKKLQEEEHHSKELRLEV-----------EK 430
Cdd:PRK02224 299 LAEAGLDDADAEAVEARREELEDRDEELRDRLEEcrvaAQAHNEEAESLREDADDLEERAEELREEAaeleseleearEA 378
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 431 LQKRMSELEKLEEAFSKSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECS----ESRLEKAEL----------- 495
Cdd:PRK02224 379 VEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATlrtaRERVEEAEAlleagkcpecg 458
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 496 -SLKDdltklkSFTVMLVDERKNMMEKIKQEERKVdglnknfKVEQGKVmdvtEKLIEESKKLLKLKSEMEEKvynltRE 574
Cdd:PRK02224 459 qPVEG------SPHVETIEEDRERVEELEAELEDL-------EEEVEEV----EERLERAEDLVEAEDRIERL-----EE 516
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 575 RDELIgklkseeeksselscsVDLLKKRLDGIEEVEREITRGRSRKGsELTCPEDNKIKELTLEIERLKKRLQQLEVVEG 654
Cdd:PRK02224 517 RREDL----------------EELIAERRETIEEKRERAEELRERAA-ELEAEAEEKREAAAEAEEEAEEAREEVAELNS 579
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 655 DLMKTEDEYDQLEqKFRTEQDKANFLSQQLEEIKHQIA---------KNKAIEKGEVVSQEAELRHRFRLEEAKSRDLKA 725
Cdd:PRK02224 580 KLAELKERIESLE-RIRTLLAAIADAEDEIERLREKREalaelnderRERLAEKRERKRELEAEFDEARIEEAREDKERA 658
|
570 580
....*....|....*....|.
gi 585420407 726 E--VQALKEKIHELMNKEDQL 744
Cdd:PRK02224 659 EeyLEQVEEKLDELREERDDL 679
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
314-783 |
1.35e-08 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 59.26 E-value: 1.35e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 314 SQEHEEMNA----KLANQESHNRQLRLK--LVGLTQRIEELEETNKNLQKAEEELQELRDKIAKGecgNSSLMAEVENLR 387
Cdd:TIGR04523 30 KQDTEEKQLekklKTIKNELKNKEKELKnlDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKN---KDKINKLNSDLS 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 388 KRVLEMEGKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQ--------------KRMSELEKLEEAFSKSKSECT 453
Cdd:TIGR04523 107 KINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEkeleklnnkyndlkKQKEELENELNLLEKEKLNIQ 186
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 454 QLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLN 533
Cdd:TIGR04523 187 KNIDKIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIK 266
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 534 KNFKVEQGKVMDVTEKLIEESKKLLKLKSEME----EKVYNLTRE-RDELIGKLKSEEEKSSELSCSVDLLKKRLDGIEE 608
Cdd:TIGR04523 267 KQLSEKQKELEQNNKKIKELEKQLNQLKSEISdlnnQKEQDWNKElKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQ 346
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 609 VEREITRGRSRKGS---ELTcPEDNKIKELTLEIERLKKRLQQLEV----VEGDLMKTEDEYDQLEQKFRTEQDKANFLS 681
Cdd:TIGR04523 347 LKKELTNSESENSEkqrELE-EKQNEIEKLKKENQSYKQEIKNLESqindLESKIQNQEKLNQQKDEQIKKLQQEKELLE 425
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 682 QQLEEIKHQIAKNKAiEKGEVVSQEAELRHRFRLEEAKSRDLKAEVQALKEKIHELMNKEDQLSQlqvDYSVLQQRFMEE 761
Cdd:TIGR04523 426 KEIERLKETIIKNNS-EIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQK---ELKSKEKELKKL 501
|
490 500
....*....|....*....|..
gi 585420407 762 ENKNKNMGQEVLNLTKELELSK 783
Cdd:TIGR04523 502 NEEKKELEEKVKDLTKKISSLK 523
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
225-449 |
1.90e-08 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 57.85 E-value: 1.90e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 225 QARKEKENAKRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAITSKSKEDRQKLLKLEV 304
Cdd:COG4942 18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRA 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 305 DFEHKASRFSQ---------EHEEMNAKLANQESHNRQLRLKLVG-----LTQRIEELEETNKNLQKAEEELQELRDKIA 370
Cdd:COG4942 98 ELEAQKEELAEllralyrlgRQPPLALLLSPEDFLDAVRRLQYLKylapaRREQAEELRADLAELAALRAELEAERAELE 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 371 KgecgnssLMAEVENLRKRV-LEMEGKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEA--FSK 447
Cdd:COG4942 178 A-------LLAELEEERAALeALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAagFAA 250
|
..
gi 585420407 448 SK 449
Cdd:COG4942 251 LK 252
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
349-737 |
2.33e-08 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 58.79 E-value: 2.33e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 349 EETNKNLQKAEEELQELRDkiakgecgnssLMAEVEN------------LRKRVLEMEGKDEEITKTESQCRELRKKLQE 416
Cdd:COG1196 175 EEAERKLEATEENLERLED-----------ILGELERqleplerqaekaERYRELKEELKELEAELLLLKLRELEAELEE 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 417 EEHHSKELRLEVEKLQKRMSELEKLEEafsksksectQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELS 496
Cdd:COG1196 244 LEAELEELEAELEELEAELAELEAELE----------ELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRE 313
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 497 LKDDLTKLKsftvmlvDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYNLTRERD 576
Cdd:COG1196 314 LEERLEELE-------EELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAE 386
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 577 ELIGKLKSEEEksselscsvdlLKKRLDGIEEVEREITRGRSRKGSELtcpEDNKIKELTLEIERLKKRLQQLEVVEgDL 656
Cdd:COG1196 387 ELLEALRAAAE-----------LAAQLEELEEAEEALLERLERLEEEL---EELEEALAELEEEEEEEEEALEEAAE-EE 451
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 657 MKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQIAKNKAIEKgevVSQEAELRHRFRLEEAKSRDLKAEVQALKEKIHE 736
Cdd:COG1196 452 AELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLL---LLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAV 528
|
.
gi 585420407 737 L 737
Cdd:COG1196 529 L 529
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
234-731 |
2.71e-08 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 58.24 E-value: 2.71e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 234 KRLNKLRDELVK----LKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAITSKSKEDRQKLLKLEvdfehK 309
Cdd:COG4717 49 ERLEKEADELFKpqgrKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLE-----K 123
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 310 ASRFSQEHEEMnaklanqeshnRQLRLKLVGLTQRIEELEEtnknlqkAEEELQELRDKIAKGECGNSSLMAEVENLRKR 389
Cdd:COG4717 124 LLQLLPLYQEL-----------EALEAELAELPERLEELEE-------RLEELRELEEELEELEAELAELQEELEELLEQ 185
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 390 VLEMegKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSectqlhlnLEKEKNLTkdl 469
Cdd:COG4717 186 LSLA--TEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEER--------LKEARLLL--- 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 470 lneleVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEK 549
Cdd:COG4717 253 -----LIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAA 327
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 550 L---IEESKKLLKLKSEMEEKVYNLTRERDELigkLKSEEEKSSELSCSVDLLKKRLDGIEEVEREITRGRSRkgseltc 626
Cdd:COG4717 328 LglpPDLSPEELLELLDRIEELQELLREAEEL---EEELQLEELEQEIAALLAEAGVEDEEELRAALEQAEEY------- 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 627 pednkiKELTLEIERLKKRLQQLEVVEGDLMKTEDEyDQLEQKFRTEQDKANFLSQQLEEIKHQIAKNKA-IEKGEVVSQ 705
Cdd:COG4717 398 ------QELKEELEELEEQLEELLGELEELLEALDE-EELEEELEELEEELEELEEELEELREELAELEAeLEQLEEDGE 470
|
490 500
....*....|....*....|....*.
gi 585420407 706 EAELRHRFRLEEAKSRDLKAEVQALK 731
Cdd:COG4717 471 LAELLQELEELKAELRELAEEWAALK 496
|
|
| Herpes_BLLF1 |
pfam05109 |
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ... |
919-1213 |
2.80e-08 |
|
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 58.39 E-value: 2.80e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 919 PDHENSTATLEIT---SPTSEEFFSSTTVIPTlgNQKPRITIIPSpnvMPQKQKSGDTTLGPERAMSPVTITTFSREKTP 995
Cdd:pfam05109 425 PESTTTSPTLNTTgfaAPNTTTGLPSSTHVPT--NLTAPASTGPT---VSTADVTSPTPAGTTSGASPVTPSPSPRDNGT 499
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 996 ESgRGAFADRPTSPIQIMTV-STSAAPAEIAVSPESQEMPMGRT-----ILKVTPEKQ------TVPTP------VRKYN 1057
Cdd:pfam05109 500 ES-KAPDMTSPTSAVTTPTPnATSPTPAVTTPTPNATSPTLGKTsptsaVTTPTPNATsptpavTTPTPnatiptLGKTS 578
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 1058 SNANIITTEDNKIHIHLGSQFKRSPGTS----GEGVSPVITVRPVNVTAEKEVSTGTVLRSPRNHLSSRPGASKVTSTIT 1133
Cdd:pfam05109 579 PTSAVTTPTPNATSPTVGETSPQANTTNhtlgGTSSTPVVTSPPKNATSAVTTGQHNITSSSTSSMSLRPSSISETLSPS 658
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 1134 ITPVTTS------SARGT----------QSVSGQDGSSQRPTPTRIPMSKGMKAGKPVVAA-PGAGNLTK-FEPRAETQS 1195
Cdd:pfam05109 659 TSDNSTShmplltSAHPTggenitqvtpASTSTHHVSTSSPAPRPGTTSQASGPGNSSTSTkPGEVNVTKgTPPKNATSP 738
|
330
....*....|....*...
gi 585420407 1196 MKIELKKSAASSTTSLGG 1213
Cdd:pfam05109 739 QAPSGQKTAVPTVTSTGG 756
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
152-495 |
4.49e-08 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 57.74 E-value: 4.49e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 152 SELDRLEEkQKETYRRMLEQLLLAEKCHRRTVYELENekhkhtdymnksddftnlLEQERERLkklleQEKAYQARKEKE 231
Cdd:PRK02224 220 EEIERYEE-QREQARETRDEADEVLEEHEERREELET------------------LEAEIEDL-----RETIAETERERE 275
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 232 NAK-RLNKLRDELVKLKSFALMLVDERQM---HIEQLGLQSQKVQDLTQKLREEEEKLKAITSKSKEDRQKLLKLEVDFE 307
Cdd:PRK02224 276 ELAeEVRDLRERLEELEEERDDLLAEAGLddaDAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLE 355
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 308 HKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLTQRIEELEETNKN----LQKAEEELQELRDKIAKGECGNSSLMAEV 383
Cdd:PRK02224 356 ERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDapvdLGNAEDFLEELREERDELREREAELEATL 435
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 384 ENLRKRVLEME-----GK---------DEEITKTESQCRELRKKLQEEEhhsKELRLEVEKLQKRMSELEKLEEAFSKsk 449
Cdd:PRK02224 436 RTARERVEEAEalleaGKcpecgqpveGSPHVETIEEDRERVEELEAEL---EDLEEEVEEVEERLERAEDLVEAEDR-- 510
|
330 340 350 360
....*....|....*....|....*....|....*....|....*...
gi 585420407 450 sectqlhlnLEKEKNLTKDLLNELEVVKSRV--KELECSESRLEKAEL 495
Cdd:PRK02224 511 ---------IERLEERREDLEELIAERRETIeeKRERAEELRERAAEL 549
|
|
| Herpes_BLLF1 |
pfam05109 |
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ... |
802-1159 |
4.74e-08 |
|
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 57.62 E-value: 4.74e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 802 PVTSTGVQTDAVSGEAAEEETPAVfirksfQEENHIMSNLRQVGLKKPVERSSVLDRyPPAANELTMRKSWIPWMRKREN 881
Cdd:pfam05109 425 PESTTTSPTLNTTGFAAPNTTTGL------PSSTHVPTNLTAPASTGPTVSTADVTS-PTPAGTTSGASPVTPSPSPRDN 497
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 882 GpsiTQEKGPRTNSspghPGEVVLSPKQG--QPLHIRVTPDHENSTATLEITSPTSeeffSSTTVIPTLGNQKPRITiIP 959
Cdd:pfam05109 498 G---TESKAPDMTS----PTSAVTTPTPNatSPTPAVTTPTPNATSPTLGKTSPTS----AVTTPTPNATSPTPAVT-TP 565
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 960 SPN-VMPQKQKSGDT---TLGPERAMSPVTITTFSREKTPESGRGAFADRP--TSPIQIMTVS--------TSAAPAEIA 1025
Cdd:pfam05109 566 TPNaTIPTLGKTSPTsavTTPTPNATSPTVGETSPQANTTNHTLGGTSSTPvvTSPPKNATSAvttgqhniTSSSTSSMS 645
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 1026 VSPESqempMGRTILKVTPEKQTVPTPVRKY-----NSNANIITTEDNKIHIHLGSQFKRSPGTSGEGVSP---VITVRP 1097
Cdd:pfam05109 646 LRPSS----ISETLSPSTSDNSTSHMPLLTSahptgGENITQVTPASTSTHHVSTSSPAPRPGTTSQASGPgnsSTSTKP 721
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 585420407 1098 vnvtAEKEVSTGTvlrSPRNHLSSRPGASKVTS--TITITPVTTSSARGTQSVSGQDG-SSQRPT 1159
Cdd:pfam05109 722 ----GEVNVTKGT---PPKNATSPQAPSGQKTAvpTVTSTGGKANSTTGGKHTTGHGArTSTEPT 779
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
125-579 |
4.97e-08 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 57.67 E-value: 4.97e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 125 KVLRVLHRDAILAQEKSIGEDVYEKPISELDRLEEKQKETYRRMLEQLLLAEKCHRRTVYELENEKHKHTDYMNKSDDFT 204
Cdd:pfam02463 596 VLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKEL 675
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 205 NLLEQERERLKKLLEQEKAYQARKEKENAKRLNKLRDELVKLKsfalMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEK 284
Cdd:pfam02463 676 LEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLE----AEELLADRVQEAQDKINEELKLLKQKIDEEEEE 751
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 285 LKAITSKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNaklanqeshNRQLRLKLvgltQRIEELEETNKNLQKAEEELQE 364
Cdd:pfam02463 752 EEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKV---------EEEKEEKL----KAQEEELRALEEELKEEAELLE 818
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 365 LRDKIAKGEcgnsslmaevENLRKRVLEMEGKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEa 444
Cdd:pfam02463 819 EEQLLIEQE----------EKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDE- 887
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 445 fsKSKSECTQLHLNLEKEKNLTKDllnelevVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVMLVDERKnMMEKIKQ 524
Cdd:pfam02463 888 --LESKEEKEKEEKKELEEESQKL-------NLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEK-EENNKEE 957
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*
gi 585420407 525 EERKVDGLNKNFKVEqgkvMDVTEKLIEESKKLLKLKSEMEEKVYNLTRERDELI 579
Cdd:pfam02463 958 EEERNKRLLLAKEEL----GKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLI 1008
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
66-772 |
6.34e-08 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 57.29 E-value: 6.34e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 66 GECERKTKKSLELSKEDLIQLLSIME-GELQAREDVIHmlKTEKTKPEVLEAHYGSAE---PEKVLRVLHRDAILAQE-K 140
Cdd:TIGR00618 152 GEFAQFLKAKSKEKKELLMNLFPLDQyTQLALMEFAKK--KSLHGKAELLTLRSQLLTlctPCMPDTYHERKQVLEKElK 229
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 141 SIGEDVYEKPISE--LDRLEEKQKETYR--RMLEQLLLAEKCHRRTVYELEN---------------EKHKHTDYMNK-- 199
Cdd:TIGR00618 230 HLREALQQTQQSHayLTQKREAQEEQLKkqQLLKQLRARIEELRAQEAVLEEtqerinrarkaaplaAHIKAVTQIEQqa 309
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 200 SDDFTNLLEQERERLKKLLEQEKAYQARKEKENAKRL--------NKLRDELVKLKSFALMLVDER---------QMHIE 262
Cdd:TIGR00618 310 QRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLlqtlhsqeIHIRDAHEVATSIREISCQQHtltqhihtlQQQKT 389
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 263 QLGLQSQKVQDLTQKLREEEEKLKAITSKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRlKLVGLT 342
Cdd:TIGR00618 390 TLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQ-ESAQSL 468
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 343 QRIEELEETNKNLQKAEEELQELRDKIAKGECGNSSLmaevenLRKRVLEMEGKDEEITKTESQCRELRKKLQEEEHHSK 422
Cdd:TIGR00618 469 KEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCP------LCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLET 542
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 423 -------ELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECsESRLEKAEL 495
Cdd:TIGR00618 543 seedvyhQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLAC-EQHALLRKL 621
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 496 SLKDDLTKL--------KSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEK 567
Cdd:TIGR00618 622 QPEQDLQDVrlhlqqcsQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLAQ 701
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 568 VYNLTRERDELIGKLKSEEEKSSELSCS-VDLLKKRLDGIEEVEREITRGRSRKGSELTCPEDNKIKELTLEIERLkkrl 646
Cdd:TIGR00618 702 CQTLLRELETHIEEYDREFNEIENASSSlGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQTG---- 777
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 647 qqlevvegdlmkteDEYDQLEQKFRTEQDKANFLSQQLEEIKHQIaknkaiekgevvsqEAELRHRFRLEEAKSRDLKAE 726
Cdd:TIGR00618 778 --------------AELSHLAAEIQFFNRLREEDTHLLKTLEAEI--------------GQEIPSDEDILNLQCETLVQE 829
|
730 740 750 760
....*....|....*....|....*....|....*....|....*.
gi 585420407 727 VQALKEKIHELMNKEDQLSQLQVDYSVLQQRFMEEENKNKNMGQEV 772
Cdd:TIGR00618 830 EEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLS 875
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
408-784 |
1.06e-07 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 56.61 E-value: 1.06e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 408 RELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLEKEKNLtkdLLNELEVVKSRVKELECSE 487
Cdd:TIGR02169 670 RSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQ---LEQEEEKLKERLEELEEDL 746
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 488 SRLEKAELSLKDDLTKLKSftvmlvdERKNMMEKIKQEERKVDGLnknfkvEQGKVMDVTEKLIEESKKLLKLKSEMEEK 567
Cdd:TIGR02169 747 SSLEQEIENVKSELKELEA-------RIEELEEDLHKLEEALNDL------EARLSHSRIPEIQAELSKLEEEVSRIEAR 813
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 568 VYNLTRERDELIGKLKSEEEKSSELSCSVDLLKKRldgIEEVEREITRGRSRKGseltcpednkikELTLEIERLKKRLQ 647
Cdd:TIGR02169 814 LREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQ---IKSIEKEIENLNGKKE------------ELEEELEELEAALR 878
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 648 QLEVVEGDLMKtedEYDQLEQKFRTEQDKANFLSQQLEEIKHQIAKNKAiEKGEVVSQEAELRHRFRL------EEAKSR 721
Cdd:TIGR02169 879 DLESRLGDLKK---ERDELEAQLRELERKIEELEAQIEKKRKRLSELKA-KLEALEEELSEIEDPKGEdeeipeEELSLE 954
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 585420407 722 DLKAEVQALKEKIHEL----MNKEDQLSQLQVDYSVLQQRFM--EEENKnknmgqEVLNLTKELELSKR 784
Cdd:TIGR02169 955 DVQAELQRVEEEIRALepvnMLAIQEYEEVLKRLDELKEKRAklEEERK------AILERIEEYEKKKR 1017
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
181-764 |
1.30e-07 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 56.21 E-value: 1.30e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 181 RTVYELENEKHKHTDYMNKSDDFTNLLEQE----RERLKKLLEQ-----EKAYQARKEKENAKRLNKLRDELVKLKSFAL 251
Cdd:TIGR00606 577 DWLHSKSKEINQTRDRLAKLNKELASLEQNknhiNNELESKEEQlssyeDKLFDVCGSQDEESDLERLKEEIEKSSKQRA 656
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 252 MLVDERQMH---IEQLGLQSQKVQDLTQKLREEEEKLKAITSKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQE 328
Cdd:TIGR00606 657 MLAGATAVYsqfITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQ 736
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 329 SHnrqlrlklvgLTQRIEELEETNKNLQKAEEELQELRDKIAKGECGNSSLMAEVENLRK--------RVLEMEGKDEE- 399
Cdd:TIGR00606 737 SI----------IDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVcltdvtimERFQMELKDVEr 806
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 400 -----ITKTES-----QCRELRKKLQEEEHHSKELRLEVEKLQK----RMSELEKLEEAFSKSKSECTQLHLNLEKEKNL 465
Cdd:TIGR00606 807 kiaqqAAKLQGsdldrTVQQVNQEKQEKQHELDTVVSKIELNRKliqdQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQF 886
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 466 TKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMD 545
Cdd:TIGR00606 887 EEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQD 966
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 546 VTEK-LIEESKKLLKLKSEMEEKVYNLTRERDELigklkseeeksselscsvDLLKKRLDGIEEVEREITRGRSRKGSEl 624
Cdd:TIGR00606 967 GKDDyLKQKETELNTVNAQLEECEKHQEKINEDM------------------RLMRQDIDTQKIQERWLQDNLTLRKRE- 1027
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 625 tcpedNKIKELTLEIERLKKRLQQLEVVEgdlmkTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQIaknkaiekgevVS 704
Cdd:TIGR00606 1028 -----NELKEVEEELKQHLKEMGQMQVLQ-----MKQEHQKLEENIDLIKRNHVLALGRQKGYEKEI-----------KH 1086
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 585420407 705 QEAELRH-RFRLEEAKSRDLKAEVQALKEKIHELMNKEDQLSQLQVDYSVLQqrfMEEENK 764
Cdd:TIGR00606 1087 FKKELREpQFRDAEEKYREMMIVMRTTELVNKDLDIYYKTLDQAIMKFHSMK---MEEINK 1144
|
|
| PTZ00108 |
PTZ00108 |
DNA topoisomerase 2-like protein; Provisional |
222-669 |
1.48e-07 |
|
DNA topoisomerase 2-like protein; Provisional
Pssm-ID: 240271 [Multi-domain] Cd Length: 1388 Bit Score: 56.21 E-value: 1.48e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 222 KAYQARKEKenakRLNKLRDELVKLKS---FALMLVDErqmhieQLGLQSQKVQDLTQKLReeeeKLKAITSKSKEDRQK 298
Cdd:PTZ00108 991 DLYKKRKEY----LLGKLERELARLSNkvrFIKHVING------ELVITNAKKKDLVKELK----KLGYVRFKDIIKKKS 1056
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 299 LLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLTQriEELEETNKNLQKAEEELQELRDKiakgecgnss 378
Cdd:PTZ00108 1057 EKITAEEEEGAEEDDEADDEDDEEELGAAVSYDYLLSMPIWSLTK--EKVEKLNAELEKKEKELEKLKNT---------- 1124
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 379 lmaEVENLRKRVLEmegkdeeitktesqcrELRKKLQEEEHHSKELRLEVEKLQKRmselekleEAFSKSKSECTQLHLN 458
Cdd:PTZ00108 1125 ---TPKDMWLEDLD----------------KFEEALEEQEEVEEKEIAKEQRLKSK--------TKGKASKLRKPKLKKK 1177
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 459 LEKEKNLTKDLLNELEVVKSRvKELECSESRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKV 538
Cdd:PTZ00108 1178 EKKKKKSSADKSKKASVVGNS-KRVDSDEKRKLDDKPDNKKSNSSGSDQEDDEEQKTKPKKSSVKRLKSKKNNSSKSSED 1256
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 539 EQGKVMDVTEKLIEESKKLLKLKSEMEEKVYNLTRERDELIGKLKSEEEKSSelscSVDLLKKRLDGIEEVEREITRGRS 618
Cdd:PTZ00108 1257 NDEFSSDDLSKEGKPKNAPKRVSAVQYSPPPPSKRPDGESNGGSKPSSPTKK----KVKKRLEGSLAALKKKKKSEKKTA 1332
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|.
gi 585420407 619 RKGSELTCPEDNKIKELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQK 669
Cdd:PTZ00108 1333 RKKKSKTRVKQASASQSSRLLRRPRKKKSDSSSEDDDDSEVDDSEDEDDED 1383
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
193-780 |
1.72e-07 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 56.21 E-value: 1.72e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 193 HTDYMNKSDDFTNLLEQERERL-KKLLEqekayqarKEKENAKRLNKLRDELvKLKSFALMLVDERQMHIEQLGLQSQKV 271
Cdd:TIGR01612 1050 HTSIYNIIDEIEKEIGKNIELLnKEILE--------EAEINITNFNEIKEKL-KHYNFDDFGKEENIKYADEINKIKDDI 1120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 272 QDLTQKLREEEEKLKAITSKSK----EDRQKLLKLEvDFEHKASrFSQEHEEMNAKLANqeshnrqlrlklvgLTQRIEE 347
Cdd:TIGR01612 1121 KNLDQKIDHHIKALEEIKKKSEnyidEIKAQINDLE-DVADKAI-SNDDPEEIEKKIEN--------------IVTKIDK 1184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 348 LEETNKNLQKAEEELQEL-RDKIAKGECGNSSlMAEVENLRKrvLEMEGKDEEITKTESQCRELR---KKLQEEEHHSKE 423
Cdd:TIGR01612 1185 KKNIYDEIKKLLNEIAEIeKDKTSLEEVKGIN-LSYGKNLGK--LFLEKIDEEKKKSEHMIKAMEayiEDLDEIKEKSPE 1261
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 424 LRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLN-------LEKEKNLTKDLLNELEVVKSRvKELECSESRLEKAELS 496
Cdd:TIGR01612 1262 IENEMGIEMDIKAEMETFNISHDDDKDHHIISKKHdenisdiREKSLKIIEDFSEESDINDIK-KELQKNLLDAQKHNSD 1340
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 497 LKDDLTKLKS-FTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEqgkvMDVTEKLIEESKKLLKL---KSEMEEKVYNlt 572
Cdd:TIGR01612 1341 INLYLNEIANiYNILKLNKIKKIIDEVKEYTKEIEENNKNIKDE----LDKSEKLIKKIKDDINLeecKSKIESTLDD-- 1414
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 573 RERDELIGKLKSEEEKSSELSCSVDLLKKRLDGIEE----VEREITRGRSRKGSELTCPEDNKIKELTLEIERLKKRLQQ 648
Cdd:TIGR01612 1415 KDIDECIKKIKELKNHILSEESNIDTYFKNADENNEnvllLFKNIEMADNKSQHILKIKKDNATNDHDFNINELKEHIDK 1494
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 649 LEVVEGDLMKTEDEYDQLEQKFRT-EQDKANFLSQQLE-EIKHQIAKNKAiEKGEVVSQEAELRHRFRLEEAKSRDLKAE 726
Cdd:TIGR01612 1495 SKGCKDEADKNAKAIEKNKELFEQyKKDVTELLNKYSAlAIKNKFAKTKK-DSEIIIKEIKDAHKKFILEAEKSEQKIKE 1573
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....
gi 585420407 727 VQALKEKIHELMNKEDQLSQLQVDYSVLQQRFMEEENKNKNMGQEVLNLTKELE 780
Cdd:TIGR01612 1574 IKKEKFRIEDDAAKNDKSNKAAIDIQLSLENFENKFLKISDIKKKINDCLKETE 1627
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
315-444 |
1.76e-07 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 55.63 E-value: 1.76e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 315 QEHEEMNAKLANQESHNRQLRLKLVGLTQRIEELEETNKNLqkaEEELQELRDKIAKGECGNSSLMAEVENLRKRVLEME 394
Cdd:COG2433 385 LIEKELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERL---EAEVEELEAELEEKDERIERLERELSEARSEERREI 461
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 585420407 395 GKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLqKRMSELEKLEEA 444
Cdd:COG2433 462 RKDREISRLDREIERLERELEEERERIEELKRKLERL-KELWKLEHSGEL 510
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
184-787 |
1.89e-07 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 55.89 E-value: 1.89e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 184 YELENEKHKHTDYMNKSDDFTNLLEQERERLKKLleQEKAYQARKEKENAKRLnkLRDELVKLKSFALMLVDERQMHIEQ 263
Cdd:pfam15921 57 YEVELDSPRKIIAYPGKEHIERVLEEYSHQVKDL--QRRLNESNELHEKQKFY--LRQSVIDLQTKLQEMQMERDAMADI 132
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 264 LGLQSQKVQDLTQKLREEEEKLKAITSKsKEDR----------------------QKLLKLEVDFEHKASRFSQEHEEMN 321
Cdd:pfam15921 133 RRRESQSQEDLRNQLQNTVHELEAAKCL-KEDMledsntqieqlrkmmlshegvlQEIRSILVDFEEASGKKIYEHDSMS 211
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 322 A----KLANQESHN-RQLRLKLVGLTQRIEELEETNKNLQ-----KAEEELQELRDK----IAKGECGNSSLMAEVENLR 387
Cdd:pfam15921 212 TmhfrSLGSAISKIlRELDTEISYLKGRIFPVEDQLEALKsesqnKIELLLQQHQDRieqlISEHEVEITGLTEKASSAR 291
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 388 KRVLEMEGKDEEIT-KTESQCRELRKKLQEEEHHSKELRLEVEKlQKRMSE--LEKLEEAFSKSKSECTQLHLNLEKEKN 464
Cdd:pfam15921 292 SQANSIQSQLEIIQeQARNQNSMYMRQLSDLESTVSQLRSELRE-AKRMYEdkIEELEKQLVLANSELTEARTERDQFSQ 370
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 465 LTKDLLNELEVVKSRVKELEcSESRLEKAELSLKDDLTKLKSFTvmlVDERKNMMEKIKQEERKVDGLNKNFKVE-QGKV 543
Cdd:pfam15921 371 ESGNLDDQLQKLLADLHKRE-KELSLEKEQNKRLWDRDTGNSIT---IDHLRRELDDRNMEVQRLEALLKAMKSEcQGQM 446
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 544 ---MDVTEKLIEESKKLLKLKSEMEEKVYNLTRERDELIGKLKSEEEKSSELSCSVDLLKKRLDGIEEVEREITRGRSRK 620
Cdd:pfam15921 447 erqMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRV 526
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 621 gseltcpeDNKIKEltleierlkkrLQQLEVVEGDLMKTEDEYDQLEQKFrTEQDKA-NFLSQQLEEIKhQIAKNKAIEK 699
Cdd:pfam15921 527 --------DLKLQE-----------LQHLKNEGDHLRNVQTECEALKLQM-AEKDKViEILRQQIENMT-QLVGQHGRTA 585
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 700 GEVVSQEAELR-----HRFRLEE---------AKSRDLKAEVQALKEKIHELMNKEDQlsQLQVDYSVLQQRfMEEENKN 765
Cdd:pfam15921 586 GAMQVEKAQLEkeindRRLELQEfkilkdkkdAKIRELEARVSDLELEKVKLVNAGSE--RLRAVKDIKQER-DQLLNEV 662
|
650 660
....*....|....*....|..
gi 585420407 766 KNMGQEVLNLTKELELSKRYSR 787
Cdd:pfam15921 663 KTSRNELNSLSEDYEVLKRNFR 684
|
|
| COG5022 |
COG5022 |
Myosin heavy chain [General function prediction only]; |
192-516 |
3.58e-07 |
|
Myosin heavy chain [General function prediction only];
Pssm-ID: 227355 [Multi-domain] Cd Length: 1463 Bit Score: 54.70 E-value: 3.58e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 192 KHTDYMNKSDDFTNL-----LEQERERLKKLLE-----QEKAYQARKEKENAKRLNKLRDELVKLKsFALMLVDERQMHI 261
Cdd:COG5022 785 RLVDYELKWRLFIKLqpllsLLGSRKEYRSYLAciiklQKTIKREKKLRETEEVEFSLKAEVLIQK-FGRSLKAKKRFSL 863
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 262 EQ---LGLQSQ-KVQDLTQKLREEEEKLKAITS---KSKEDRQKLLKLEVDFEhkaSRFSQEHEEMNAKLANQESHNRQL 334
Cdd:COG5022 864 LKketIYLQSAqRVELAERQLQELKIDVKSISSlklVNLELESEIIELKKSLS---SDLIENLEFKTELIARLKKLLNNI 940
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 335 RLKLvgltQRIEELEEtNKNLQKAEEELQELRDKIAKGECGNSSLMAEVENLRKRVLEMEGKDEEITKTESQcrelRKKL 414
Cdd:COG5022 941 DLEE----GPSIEYVK-LPELNKLHEVESKLKETSEEYEDLLKKSTILVREGNKANSELKNFKKELAELSKQ----YGAL 1011
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 415 QEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLEKEKNLTKDLLNeLEVVKSRVKELECSESRLEKAE 494
Cdd:COG5022 1012 QESTKQLKELPVEVAELQSASKIISSESTELSILKPLQKLKGLLLLENNQLQARYKA-LKLRRENSLLDDKQLYQLESTE 1090
|
330 340
....*....|....*....|...
gi 585420407 495 -LSLKDDLTKLKSFTVMLVDERK 516
Cdd:COG5022 1091 nLLKTINVKDLEVTNRNLVKPAN 1113
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
275-494 |
6.06e-07 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 53.23 E-value: 6.06e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 275 TQKLREEEEKLKAITSKSKEDRQKLLKLEVdfehKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLTQRIEELEetnKN 354
Cdd:COG4942 19 ADAAAEAEAELEQLQQEIAELEKELAALKK----EEKALLKQLAALERRIAALARRIRALEQELAALEAELAELE---KE 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 355 LQKAEEELQELRDKIAK--------GECGNSSLMAEVENLRKRVLEMEGKDEEITKTESQCRELRKKLQEEEHHSKELRL 426
Cdd:COG4942 92 IAELRAELEAQKEELAEllralyrlGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEA 171
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 585420407 427 EVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLEKEKNLTKDLLNELevvKSRVKELECSESRLEKAE 494
Cdd:COG4942 172 ERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAEL---QQEAEELEALIARLEAEA 236
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
185-780 |
6.45e-07 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 54.03 E-value: 6.45e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 185 ELENEKHKHTDYMNKSDDFTNLLEQERerlKKLLEQEKAYQARKEKENAKRlNKLRDELV----KLKSFA---LMLVDER 257
Cdd:pfam01576 72 ELEEILHELESRLEEEEERSQQLQNEK---KKMQQHIQDLEEQLDEEEAAR-QKLQLEKVtteaKIKKLEediLLLEDQN 147
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 258 QMHIEQLGLQSQKVQDLTQKLREEEEKLKAITSKSKEDRQKLLKLEVDFEhKASRFSQEHEEMNAKLanqESHNRQLRLK 337
Cdd:pfam01576 148 SKLSKERKLLEERISEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLK-KEEKGRQELEKAKRKL---EGESTDLQEQ 223
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 338 LVGLTQRIEELEetnKNLQKAEEELQELRDKIAKGECGNSSLMAEVENLRKRVLE----MEGKDEEITKTESQCRELRKK 413
Cdd:pfam01576 224 IAELQAQIAELR---AQLAKKEEELQAALARLEEETAQKNNALKKIRELEAQISElqedLESERAARNKAEKQRRDLGEE 300
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 414 LQ----EEEHHSKELRLEVEKLQKRMSELEKLEEAF-SKSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSES 488
Cdd:pfam01576 301 LEalktELEDTLDTTAAQQELRSKREQEVTELKKALeEETRSHEAQLQEMRQKHTQALEELTEQLEQAKRNKANLEKAKQ 380
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 489 RLEKAELSLKDDLTKLKSftvmlvderknmmekikqeeRKVDGLNKNFKVEqGKVMDVTEKLIEESKKllklKSEMEEKV 568
Cdd:pfam01576 381 ALESENAELQAELRTLQQ--------------------AKQDSEHKRKKLE-GQLQELQARLSESERQ----RAELAEKL 435
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 569 YNLTRERDELIGKLKSEEEKSSELSCSVDLLKKRLDGIEEVEREITRGRSRKGSELTCPED--NKIKELTLEIERLKKRL 646
Cdd:pfam01576 436 SKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDerNSLQEQLEEEEEAKRNV 515
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 647 Q-QLEVVEGDLM----KTEDE---YDQLEQKFRTEQDKANFLSQQLEEikhqiaKNKAIEKGEvvsqeaelRHRFRLEEa 718
Cdd:pfam01576 516 ErQLSTLQAQLSdmkkKLEEDagtLEALEEGKKRLQRELEALTQQLEE------KAAAYDKLE--------KTKNRLQQ- 580
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 585420407 719 KSRDLKAEVQALKEKIHELMNKEDQLSQLQVDYSVLQQRFMEEENKNKNMGQE----VLNLTKELE 780
Cdd:pfam01576 581 ELDDLLVDLDHQRQLVSNLEKKQKKFDQMLAEEKAISARYAEERDRAEAEAREketrALSLARALE 646
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
341-799 |
2.04e-06 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 52.38 E-value: 2.04e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 341 LTQRIEELEETNKNLQKAEEELQELRDKIAKgecgNSSLMAEVENLRKRVLEMEGKDEEItktesqcRELRKKLQEEE-- 418
Cdd:TIGR02169 158 IIDEIAGVAEFDRKKEKALEELEEVEENIER----LDLIIDEKRQQLERLRREREKAERY-------QALLKEKREYEgy 226
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 419 ---HHSKELRLEVEKLQKRMS----ELEKLEEAFSKSKSECTQLHLNLEKEKNLTKDLL-NELEVVKSRVKELECSESRL 490
Cdd:TIGR02169 227 ellKEKEALERQKEAIERQLAsleeELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGeEEQLRVKEKIGELEAEIASL 306
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 491 EKAELSLKDDLTKLKsftvmlvDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYN 570
Cdd:TIGR02169 307 ERSIAEKERELEDAE-------ERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKE 379
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 571 LTRERDELigklkseeeksselscsvDLLKKRLDGIEEVEREITRGRSRKGSELtcpednkiKELTLEIERLKkrlQQLE 650
Cdd:TIGR02169 380 FAETRDEL------------------KDYREKLEKLKREINELKRELDRLQEEL--------QRLSEELADLN---AAIA 430
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 651 VVEGDLMKTEDEYDQLEQKFRTEQdkanflsQQLEEIKHQIAKnkaiekgevvsqeaelrhrfrlEEAKSRDLKAEVQAL 730
Cdd:TIGR02169 431 GIEAKINELEEEKEDKALEIKKQE-------WKLEQLAADLSK----------------------YEQELYDLKEEYDRV 481
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 585420407 731 kekihelmnkEDQLSQLQVDYSVLQQRfmeeenknknmgqevlnltkelelskrySRALRPSVNGRRMV 799
Cdd:TIGR02169 482 ----------EKELSKLQRELAEAEAQ----------------------------ARASEERVRGGRAV 512
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
185-775 |
2.27e-06 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 52.36 E-value: 2.27e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 185 ELENEKHKHTDYMNKSDDFTNLLEQERERLKKLLEQEKAYQARKEKEnaKRLNKLRDELVKLKSFALMLVDERQMHIEQL 264
Cdd:TIGR00606 232 QLESSREIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRK--KQMEKDNSELELKMEKVFQGTDEQLNDLYHN 309
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 265 glQSQKVQDLTQKLREEEEKLKAITSKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKlaNQESHNRQLRLKLVGLtQR 344
Cdd:TIGR00606 310 --HQRTVREKERELVDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRAR--DSLIQSLATRLELDGF-ER 384
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 345 IEELEETNKNLQKAEEELQELRDKIAKGECGN--SSLMAEVENLRKRVLEMEG-------KDEEITKTESQCRELRKKLQ 415
Cdd:TIGR00606 385 GPFSERQIKNFHTLVIERQEDEAKTAAQLCADlqSKERLKQEQADEIRDEKKGlgrtielKKEILEKKQEELKFVIKELQ 464
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 416 EEEHHSKELRLEVEKLQKRMSELEKLEEafsKSKSECtqLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAEL 495
Cdd:TIGR00606 465 QLEGSSDRILELDQELRKAERELSKAEK---NSLTET--LKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEM 539
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 496 SLKDDLT------KLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVY 569
Cdd:TIGR00606 540 LTKDKMDkdeqirKIKSRHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEE 619
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 570 NLTRERDELIgklkseeeksseLSCSVDLLKKRLDGIEEvEREITRGRSRKGSELTCPEDNKIKELTLEIERLKKRLQQL 649
Cdd:TIGR00606 620 QLSSYEDKLF------------DVCGSQDEESDLERLKE-EIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRV 686
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 650 EVVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQI---AKNKAIEKGEVVSQEAELRHRFRLEEAKSRDLKAE 726
Cdd:TIGR00606 687 FQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMlglAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKND 766
|
570 580 590 600
....*....|....*....|....*....|....*....|....*....
gi 585420407 727 VQALKEKIHELMNKEDQLSQLQVDYSVLQQRFMEEENKNKNMGQEVLNL 775
Cdd:TIGR00606 767 IEEQETLLGTIMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQAAKL 815
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
294-448 |
3.65e-06 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 49.54 E-value: 3.65e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 294 EDRQKLLKLEvDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLTQRIEELEetnKNLQKAEEELQELRDKIAK-- 371
Cdd:COG1579 4 EDLRALLDLQ-ELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLE---KEIKRLELEIEEVEARIKKye 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 372 ---GECGNS----SLMAEVENLRKRV-------LEMEGKDEEITKTESQCRELRKKLQEE-EHHSKELRLEVEKLQKRMS 436
Cdd:COG1579 80 eqlGNVRNNkeyeALQKEIESLKRRIsdledeiLELMERIEELEEELAELEAELAELEAElEEKKAELDEELAELEAELE 159
|
170
....*....|..
gi 585420407 437 ELEKLEEAFSKS 448
Cdd:COG1579 160 ELEAEREELAAK 171
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
155-530 |
5.26e-06 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 50.66 E-value: 5.26e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 155 DRLEEKQKETYRRMLEQLLLAEKCHRRTVYELENE----KHKHTDYMNKSDDFTNLLEQERERLKKLLEQEKAYQArkek 230
Cdd:pfam07888 54 NRQREKEKERYKRDREQWERQRRELESRVAELKEElrqsREKHEELEEKYKELSASSEELSEEKDALLAQRAAHEA---- 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 231 enakRLNKLRDELVKLKSFALmlvdERQMHIEQLglqSQKVQDLTQKLREEEEKLKAITSKSKEDRQKLLKLEVDFehka 310
Cdd:pfam07888 130 ----RIRELEEDIKTLTQRVL----ERETELERM---KERAKKAGAQRKEEEAERKQLQAKLQQTEEELRSLSKEF---- 194
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 311 srfsqehEEMNAKLANQESHNRQLRLKLVGLTQRIEELEETNKNLQKAEEELQELRDKIAKGECGNSSLMAEVENL---R 387
Cdd:pfam07888 195 -------QELRNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEAENEALLEELRSLQERLNASERKVEGLGEELSSMaaqR 267
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 388 KRVL-EMEGKDEEITKTESQCRELRKKLQEEEHHSKELR--------LEVEKLQKRMSELEKLEEAFSKSKSECTQLHLN 458
Cdd:pfam07888 268 DRTQaELHQARLQAAQLTLQLADASLALREGRARWAQERetlqqsaeADKDRIEKLSAELQRLEERLQEERMEREKLEVE 347
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 585420407 459 LEKEKNLtkdllnelevvkSRVkelECSESRLEKAElsLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVD 530
Cdd:pfam07888 348 LGREKDC------------NRV---QLSESRRELQE--LKASLRVAQKEKEQLQAEKQELLEYIRQLEQRLE 402
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
76-771 |
5.31e-06 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 50.94 E-value: 5.31e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 76 LELSKEDLIQLLSIMEGELQAREDVIHMLKTEKTKPEV----LEAHYGSAE--------------------PEKVLRVLH 131
Cdd:pfam01576 66 LAARKQELEEILHELESRLEEEEERSQQLQNEKKKMQQhiqdLEEQLDEEEaarqklqlekvtteakikklEEDILLLED 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 132 RDAILAQEKSIGEDVYEKPISELDRLEEKQKE------TYRRMLEQLLLAEKCHRRTVYELENEKHkhtdymnKSDDFTN 205
Cdd:pfam01576 146 QNSKLSKERKLLEERISEFTSNLAEEEEKAKSlsklknKHEAMISDLEERLKKEEKGRQELEKAKR-------KLEGEST 218
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 206 LLEQERERLKKLLEQEKAYQARKEKENAKRLNKLRDELVKlKSFALMLVDERQMHIEQLG-------LQSQKVQDLTQKL 278
Cdd:pfam01576 219 DLQEQIAELQAQIAELRAQLAKKEEELQAALARLEEETAQ-KNNALKKIRELEAQISELQedleserAARNKAEKQRRDL 297
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 279 REEEEKLKA-------ITSKSKEDR----QKLLKLEVDFEHKASRFSQEHEEMNAKlanqesHNRQlrlkLVGLTQRIEE 347
Cdd:pfam01576 298 GEELEALKTeledtldTTAAQQELRskreQEVTELKKALEEETRSHEAQLQEMRQK------HTQA----LEELTEQLEQ 367
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 348 LEETNKNLQKAEEELqelrdkiakgECGNSSLMAEVENLRKRVLEMEGKDEeitKTESQCRELRKKLQEEEHHSKELrle 427
Cdd:pfam01576 368 AKRNKANLEKAKQAL----------ESENAELQAELRTLQQAKQDSEHKRK---KLEGQLQELQARLSESERQRAEL--- 431
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 428 VEKLQKRMSELEKLEEAFSKSKSECTQLHLNLEKEKNLTKDllnelevvksrVKELECSESRlEKAELSlkddlTKLKSf 507
Cdd:pfam01576 432 AEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQD-----------TQELLQEETR-QKLNLS-----TRLRQ- 493
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 508 tvmLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLlklkSEMEEKVYNLTRErdeligklkseee 587
Cdd:pfam01576 494 ---LEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTL----EALEEGKKRLQRE------------- 553
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 588 ksselscsVDLLKKRLDGIEEVEREITRGRSRKGSEL---TCPEDNKiKELTLEIERLKKRLQQLEVVEGDL-MKTEDEY 663
Cdd:pfam01576 554 --------LEALTQQLEEKAAAYDKLEKTKNRLQQELddlLVDLDHQ-RQLVSNLEKKQKKFDQMLAEEKAIsARYAEER 624
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 664 DQLEQKFRTEQDKANFLSQQLEE---IKHQIAKNKAIEKGE----VVSQEAELRHRFRLEEAKsRDLKAEVQALKEKIHE 736
Cdd:pfam01576 625 DRAEAEAREKETRALSLARALEEaleAKEELERTNKQLRAEmedlVSSKDDVGKNVHELERSK-RALEQQVEEMKTQLEE 703
|
730 740 750
....*....|....*....|....*....|....*....
gi 585420407 737 LMNK----EDQLSQLQVDYSVLQQRFMEEENKNKNMGQE 771
Cdd:pfam01576 704 LEDElqatEDAKLRLEVNMQALKAQFERDLQARDEQGEE 742
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
60-441 |
6.51e-06 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 50.73 E-value: 6.51e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 60 RHLKTSGECER---KTKKSLELSKEDLIQL----------LSIMEGELQA--------REDVIHMLKTEKTKPEVLEAHY 118
Cdd:PRK04863 283 VHLEEALELRRelyTSRRQLAAEQYRLVEMarelaelneaESDLEQDYQAasdhlnlvQTALRQQEKIERYQADLEELEE 362
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 119 GSAEPEKVLRVLHRDAILAQEK-SIGEDVYEKPISEL----DRLEEKQKET--YRRMLEQLLLAEKCHRRTVYELENEKH 191
Cdd:PRK04863 363 RLEEQNEVVEEADEQQEENEARaEAAEEEVDELKSQLadyqQALDVQQTRAiqYQQAVQALERAKQLCGLPDLTADNAED 442
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 192 KHTDYMNKSDDFTNLLEQERERL---KKLLEQ-EKAYQA-RK-----EKENAKrlNKLRDELVKLKSFalmlvderQMHI 261
Cdd:PRK04863 443 WLEEFQAKEQEATEELLSLEQKLsvaQAAHSQfEQAYQLvRKiagevSRSEAW--DVARELLRRLREQ--------RHLA 512
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 262 EQLGLQSQKVQDLTQKLREEEEKLKAITSKSKEDRQKLLKlEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGL 341
Cdd:PRK04863 513 EQLQQLRMRLSELEQRLRQQQRAERLLAEFCKRLGKNLDD-EDELEQLQEELEARLESLSESVSEARERRMALRQQLEQL 591
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 342 TQRIEELEETNKNLQKAEEELQELRDKIakGECGNSSlmAEVENLRKRVLEMEgkdeeitktesqcRELRKKLQEEEHHS 421
Cdd:PRK04863 592 QARIQRLAARAPAWLAAQDALARLREQS--GEEFEDS--QDVTEYMQQLLERE-------------RELTVERDELAARK 654
|
410 420
....*....|....*....|.
gi 585420407 422 KELRLEVEKLQKR-MSELEKL 441
Cdd:PRK04863 655 QALDEEIERLSQPgGSEDPRL 675
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
185-548 |
8.69e-06 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 50.02 E-value: 8.69e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 185 ELENEKHKHTDYMNKSDDFTNLLEQERERLKKLLEQEKayqaRKEKENAKRLNKLRDELVKLKSfalmLVDERQMHIEQL 264
Cdd:TIGR04523 315 ELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELT----NSESENSEKQRELEEKQNEIEK----LKKENQSYKQEI 386
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 265 GLQSQKVQDLTQKLREEEEKLKAITSKSKEDRQKLLKLEVDFEhkasRFSQEHEEMNAKLANQESHNRQLRLKLVGLTQR 344
Cdd:TIGR04523 387 KNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIE----RLKETIIKNNSEIKDLTNQDSVKELIIKNLDNT 462
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 345 IEELEE-----------TNKNLQKAEEELQELRDKIAKGECGNSSLMAEVENLRKRVLEMEGKDE----EITKTESQCRE 409
Cdd:TIGR04523 463 RESLETqlkvlsrsinkIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEklesEKKEKESKISD 542
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 410 LRKKLQEEEHHSKELRLEVEKLQKRmSELEKLEEAFSKSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESR 489
Cdd:TIGR04523 543 LEDELNKDDFELKKENLEKEIDEKN-KEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEK 621
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*....
gi 585420407 490 LEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTE 548
Cdd:TIGR04523 622 AKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEIIKKIKESKTKIDDIIE 680
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
151-699 |
1.09e-05 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 49.90 E-value: 1.09e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 151 ISELDRLEEKQKETYRRMLE---QLLLAEKCHRRTVYELENEKhkhTDYMNKSDDFtNLLEQERERLKKLLEQEKAYQAr 227
Cdd:PRK01156 182 ISNIDYLEEKLKSSNLELENikkQIADDEKSHSITLKEIERLS---IEYNNAMDDY-NNLKSALNELSSLEDMKNRYES- 256
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 228 KEKENAKRLNKLRDELVKLKSfalmlVDERQMHIEQLGLQSQ--------KVQDLTQKLREEEEKLKAITSKSKEDRQKL 299
Cdd:PRK01156 257 EIKTAESDLSMELEKNNYYKE-----LEERHMKIINDPVYKNrnyindyfKYKNDIENKKQILSNIDAEINKYHAIIKKL 331
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 300 LKLEVDFehkaSRFSQEHEEMNaKLANQESHNRQLRLKLVGLTQRIEELEETNKNLQKAEEELQELRDKIAKGECGNSS- 378
Cdd:PRK01156 332 SVLQKDY----NDYIKKKSRYD-DLNNQILELEGYEMDYNSYLKSIESLKKKIEEYSKNIERMSAFISEILKIQEIDPDa 406
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 379 LMAEVENLRKRVLEMEGKdeeITKTESQCRELRKKLQEEEHHSKELR-----------LEVEKLQKRM----SELEKLEE 443
Cdd:PRK01156 407 IKKELNEINVKLQDISSK---VSSLNQRIRALRENLDELSRNMEMLNgqsvcpvcgttLGEEKSNHIInhynEKKSRLEE 483
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 444 AFSKSKSECTQLHlnlEKEKNLtKDLLNELEvvKSRVKELECSESRLEKAELSLKDDLTKL-----KSFTVMLVDERKNM 518
Cdd:PRK01156 484 KIREIEIEVKDID---EKIVDL-KKRKEYLE--SEEINKSINEYNKIESARADLEDIKIKInelkdKHDKYEEIKNRYKS 557
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 519 MEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYNLTRERDELIGKLKSEEEKSSELSCSVDL 598
Cdd:PRK01156 558 LKLEDLDSKRTSWLNALAVISLIDIETNRSRSNEIKKQLNDLESRLQEIEIGFPDDKSYIDKSIREIENEANNLNNKYNE 637
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 599 LKKRLDGIEEVEREITRGRSRKgSELTCPEDNKiKELTLEIERLKKRLQQlevVEGDLMKTEDEYDQLEQKFRTEQDKAN 678
Cdd:PRK01156 638 IQENKILIEKLRGKIDNYKKQI-AEIDSIIPDL-KEITSRINDIEDNLKK---SRKALDDAKANRARLESTIEILRTRIN 712
|
570 580
....*....|....*....|.
gi 585420407 679 FLSQQLEEIKHQIAKNKAIEK 699
Cdd:PRK01156 713 ELSDRINDINETLESMKKIKK 733
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
207-787 |
1.11e-05 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 49.79 E-value: 1.11e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 207 LEQERERLKKLLEQEKAYQARKEKEnaKRlnKLRDELVKLKSfalMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLK 286
Cdd:pfam01576 269 LEAQISELQEDLESERAARNKAEKQ--RR--DLGEELEALKT---ELEDTLDTTAAQQELRSKREQEVTELKKALEEETR 341
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 287 AITSKSKEDRQK----LLKLEVDFEhKASRFSQEHEEMNAKLanqESHNRQLRLKLVGLTQRIEELEETNKnlqKAEEEL 362
Cdd:pfam01576 342 SHEAQLQEMRQKhtqaLEELTEQLE-QAKRNKANLEKAKQAL---ESENAELQAELRTLQQAKQDSEHKRK---KLEGQL 414
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 363 QELRDKIAKGECGN-------SSLMAEVENLRKRVLEMEGKD----EEITKTESQCRELRKKLQEEEHH-----SKELRL 426
Cdd:pfam01576 415 QELQARLSESERQRaelaeklSKLQSELESVSSLLNEAEGKNiklsKDVSSLESQLQDTQELLQEETRQklnlsTRLRQL 494
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 427 EVEK--LQKRMSELEKLEEAFSK-----------SKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKA 493
Cdd:pfam01576 495 EDERnsLQEQLEEEEEAKRNVERqlstlqaqlsdMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKT 574
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 494 ELSLKDDLTKLksftVMLVDERKNMMEKIKQEERKVDGLNKNFKVeqgkvmdVTEKLIEESKKLLKLKSEMEEKVYNLTR 573
Cdd:pfam01576 575 KNRLQQELDDL----LVDLDHQRQLVSNLEKKQKKFDQMLAEEKA-------ISARYAEERDRAEAEAREKETRALSLAR 643
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 574 ERDELIGKLKSEEEKSSELSCSVDLLKKRLDGIEEVEREITRgrSRKGSEltcpedNKIKELTLEIERLKKRLQQLE--- 650
Cdd:pfam01576 644 ALEEALEAKEELERTNKQLRAEMEDLVSSKDDVGKNVHELER--SKRALE------QQVEEMKTQLEELEDELQATEdak 715
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 651 ---VVEGDLMKTEDEYD------QLEQKFRTEQDKANFLSQQLEEIKHQIAKNKAIEK---GEVVSQEAELRHRFRLEEA 718
Cdd:pfam01576 716 lrlEVNMQALKAQFERDlqardeQGEEKRRQLVKQVRELEAELEDERKQRAQAVAAKKkleLDLKELEAQIDAANKGREE 795
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 585420407 719 KSRDLKAEVQALKEKIHELmnKEDQLSQlqvDYSVLQQRfmEEENKNKNMGQEVLNLTKELELSKRYSR 787
Cdd:pfam01576 796 AVKQLKKLQAQMKDLQREL--EEARASR---DEILAQSK--ESEKKLKNLEAELLQLQEDLAASERARR 857
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
152-350 |
1.24e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 48.99 E-value: 1.24e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 152 SELDRLEEKQKETyRRMLEQLLLAEKCHRRTVYELENEKHKHTDYMNKSDDFTNLLEQERERLKKLLEQEKAYQARKEKE 231
Cdd:COG4942 27 AELEQLQQEIAEL-EKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEE 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 232 NAKRLNKL---------------RDELVKLKSFALM--LVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAITSKSKE 294
Cdd:COG4942 106 LAELLRALyrlgrqpplalllspEDFLDAVRRLQYLkyLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEE 185
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 585420407 295 DRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLTQRIEELEE 350
Cdd:COG4942 186 ERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
262-784 |
1.52e-05 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 49.40 E-value: 1.52e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 262 EQLGLQSQKVQDLTQKLREEEEKLKAITSKSKEDRQKLLKLEVDFEHKASRFSqEHEEMNAKLANQEshnRQLRLKLVGL 341
Cdd:pfam01576 5 EEMQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCA-EAEEMRARLAARK---QELEEILHEL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 342 TQRIEELEETNKNLQ----KAEEELQELRDKIAKGECGNSSLM-------AEVENLRKRVLEMEGKDEEITKT----ESQ 406
Cdd:pfam01576 81 ESRLEEEEERSQQLQnekkKMQQHIQDLEEQLDEEEAARQKLQlekvtteAKIKKLEEDILLLEDQNSKLSKErkllEER 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 407 CRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLEKEKNLTKDLLNELevvKSRVKELECS 486
Cdd:pfam01576 161 ISEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAEL---QAQIAELRAQ 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 487 esrLEKAELSLKDDLTKLKSFTVmlvdERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEE 566
Cdd:pfam01576 238 ---LAKKEEELQAALARLEEETA----QKNNALKKIRELEAQISELQEDLESERAARNKAEKQRRDLGEELEALKTELED 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 567 KVyNLTRERDELigklkseeekSSELSCSVDLLKKRLDgieeverEITRGRSRKGSELTCPEDNKIKELTLEIERLKKRL 646
Cdd:pfam01576 311 TL-DTTAAQQEL----------RSKREQEVTELKKALE-------EETRSHEAQLQEMRQKHTQALEELTEQLEQAKRNK 372
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 647 QQLE----VVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEEI--KHQIAKNKAIEKGEVVSQ-EAELR---HRFRLE 716
Cdd:pfam01576 373 ANLEkakqALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQELqaRLSESERQRAELAEKLSKlQSELEsvsSLLNEA 452
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 585420407 717 EAKSRDLKAEVQALKEKIH---ELMNKEDQ--------LSQLQVDYSVLQQRFMEEENKNKNMGQEVLNLTKELELSKR 784
Cdd:pfam01576 453 EGKNIKLSKDVSSLESQLQdtqELLQEETRqklnlstrLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKK 531
|
|
| COG1340 |
COG1340 |
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]; |
269-575 |
2.45e-05 |
|
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 47.60 E-value: 2.45e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 269 QKVQDLTQKLREEEEKLKAITSKSKEDRQKLLKLEvdfeHKASRFSQEHEEMNAKLanqeshnRQLRLKLVGLtqrIEEL 348
Cdd:COG1340 1 SKTDELSSSLEELEEKIEELREEIEELKEKRDELN----EELKELAEKRDELNAQV-------KELREEAQEL---REKR 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 349 EETNKNLQKAEEELQELRDKIakgecgnSSLMAEVENLRKRVLEMEGKDEEITKTESQCRELRKKLQEEEHHSKELRLEV 428
Cdd:COG1340 67 DELNEKVKELKEERDELNEKL-------NELREELDELRKELAELNKAGGSIDKLRKEIERLEWRQQTEVLSPEEEKELV 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 429 EKLQKRMSELEKLEEAfsksksectqlhlnlEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFT 508
Cdd:COG1340 140 EKIKELEKELEKAKKA---------------LEKNEKLKELRAELKELRKEAEEIHKKIKELAEEAQELHEEMIELYKEA 204
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 585420407 509 VMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYNLTRER 575
Cdd:COG1340 205 DELRKEADELHKEIVEAQEKADELHEEIIELQKELRELRKELKKLRKKQRALKREKEKEELEEKAEE 271
|
|
| Spc7 |
smart00787 |
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ... |
340-484 |
6.70e-05 |
|
Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.
Pssm-ID: 197874 [Multi-domain] Cd Length: 312 Bit Score: 46.55 E-value: 6.70e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 340 GLTQRIEELEETNKNLQKAEEELQELRDKIAKGecgNSSLMAEVENLRKRVLEMEGKDEEITKtesqcrELRKKLQEEEH 419
Cdd:smart00787 148 GLDENLEGLKEDYKLLMKELELLNSIKPKLRDR---KDALEEELRQLKQLEDELEDCDPTELD------RAKEKLKKLLQ 218
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 585420407 420 HSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLEKEKNLTKDL-LNELEVVKSRVKELE 484
Cdd:smart00787 219 EIMIKVKKLEELEEELQELESKIEDLTNKKSELNTEIAEAEKKLEQCRGFtFKEIEKLKEQLKLLQ 284
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
240-780 |
6.71e-05 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 47.04 E-value: 6.71e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 240 RDELVKLKSFALMLVDErqmhIEQLGLQSQKVQDLTQKLREEEEKLKAITSKSKEDRQKLLKLEVDFEHKASRFSQEHEE 319
Cdd:pfam05557 1 RAELIESKARLSQLQNE----KKQMELEHKRARIELEKKASALKRQLDRESDRNQELQKRIRLLEKREAEAEEALREQAE 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 320 MN-AKLANQESHNRQLRLKlvglTQRIEELEETNKNLQKaeeELQELRDKIAKGECGNSSLMAEVENLRKRVLEMEGKDE 398
Cdd:pfam05557 77 LNrLKKKYLEALNKKLNEK----ESQLADAREVISCLKN---ELSELRRQIQRAELELQSTNSELEELQERLDLLKAKAS 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 399 EITKTESQCRELRKKLQEEEHHSKEL----------RLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLN------LEKE 462
Cdd:pfam05557 150 EAEQLRQNLEKQQSSLAEAEQRIKELefeiqsqeqdSEIVKNSKSELARIPELEKELERLREHNKHLNENienkllLKEE 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 463 KNLTKDLLNELEVVKSRVKELECSESRLE-------KAELSLKDDLTK---LKSFTVMLVDERKNMMEKIKQEERKVDGL 532
Cdd:pfam05557 230 VEDLKRKLEREEKYREEAATLELEKEKLEqelqswvKLAQDTGLNLRSpedLSRRIEQLQQREIVLKEENSSLTSSARQL 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 533 NKNFKVEQGKVMDVTEKLIEESKKLLKLKS---EMEEKVYNLTRERDELIGKLKSEEEKSSELSCSVDLLkKRLDGIEEV 609
Cdd:pfam05557 310 EKARRELEQELAQYLKKIEDLNKKLKRHKAlvrRLQRRVLLLTKERDGYRAILESYDKELTMSNYSPQLL-ERIEEAEDM 388
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 610 EREITRGRSRKGSELTCPEDN----KIKELTLEIErLKKRLQQLEVveGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLE 685
Cdd:pfam05557 389 TQKMQAHNEEMEAQLSVAEEElggyKQQAQTLERE-LQALRQQESL--ADPSYSKEEVDSLRRKLETLELERQRLREQKN 465
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 686 EIKHQIAKNKAIEKGEVVSQEAeLRHR-------FRLEEAKSRDLKAEVQALKEKIHELMNKEDQLSQLQVDYSVLQQRf 758
Cdd:pfam05557 466 ELEMELERRCLQGDYDPKKTKV-LHLSmnpaaeaYQQRKNQLEKLQAEIERLKRLLKKLEDDLEQVLRLPETTSTMNFK- 543
|
570 580
....*....|....*....|..
gi 585420407 759 meeenknknmgqEVLNLTKELE 780
Cdd:pfam05557 544 ------------EVLDLRKELE 553
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
153-424 |
6.81e-05 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 47.04 E-value: 6.81e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 153 ELDRL-EEKQKETYRRMLEQLLLAEKCHRRTVYELENEKHKHTDYMNKsddftnllEQERERLKKLLEQEKAyqaRKEKE 231
Cdd:pfam17380 349 ELERIrQEERKRELERIRQEEIAMEISRMRELERLQMERQQKNERVRQ--------ELEAARKVKILEEERQ---RKIQQ 417
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 232 NAKRLNKLRDELVKLKSFAL-MLVDERQMHIEQLGLQSQKVQDLTQKLREEEEklkaitskskEDRQKLLKLEvdfehKA 310
Cdd:pfam17380 418 QKVEMEQIRAEQEEARQREVrRLEEERAREMERVRLEEQERQQQVERLRQQEE----------ERKRKKLELE-----KE 482
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 311 SRFSQEHEEMNAKLANQESHNRQlrlklvgltQRIEELEETNKNLQKAEEELQ-----ELRDKIAKGECGNSSLMAEven 385
Cdd:pfam17380 483 KRDRKRAEEQRRKILEKELEERK---------QAMIEEERKRKLLEKEMEERQkaiyeEERRREAEEERRKQQEMEE--- 550
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 585420407 386 lRKRVLE-MEGKDEEITKTES--QCRELRKKLQEEEHHSKEL 424
Cdd:pfam17380 551 -RRRIQEqMRKATEERSRLEAmeREREMMRQIVESEKARAEY 591
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
262-506 |
8.82e-05 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 46.55 E-value: 8.82e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 262 EQLGLQSQKVQDLTQKLREEEEKLKAITSKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNaklanqeshnrqlrlklvgl 341
Cdd:PHA02562 181 QQIQTLDMKIDHIQQQIKTYNKNIEEQRKKNGENIARKQNKYDELVEEAKTIKAEIEELT-------------------- 240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 342 tqriEELEETNKNLQKAEEELQELRDKIAKgecgnssLMAEVENLRKrVLEMEGKDEEITKTESQCRELRKKLQEEEHHS 421
Cdd:PHA02562 241 ----DELLNLVMDIEDPSAALNKLNTAAAK-------IKSKIEQFQK-VIKMYEKGGVCPTCTQQISEGPDRITKIKDKL 308
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 422 KELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELEcSESRLEKAELS-LKDD 500
Cdd:PHA02562 309 KELQHSLEKLDTAIDELEEIMDEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQ-AEFVDNAEELAkLQDE 387
|
....*.
gi 585420407 501 LTKLKS 506
Cdd:PHA02562 388 LDKIVK 393
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
381-495 |
9.17e-05 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 46.69 E-value: 9.17e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 381 AEVENLRKRVLeMEGKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLE 460
Cdd:PRK12704 49 KEAEAIKKEAL-LEAKEEIHKLRNEFEKELRERRNELQKLEKRLLQKEENLDRKLELLEKREEELEKKEKELEQKQQELE 127
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 585420407 461 KEK----NLTKDLLNELEVV--------KSRV-KELEcSESRLEKAEL 495
Cdd:PRK12704 128 KKEeeleELIEEQLQELERIsgltaeeaKEILlEKVE-EEARHEAAVL 174
|
|
| EzrA |
pfam06160 |
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like ... |
201-481 |
9.28e-05 |
|
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like cell-division protein FtsZ polymerizes into a ring structure that establishes the location of the nascent division site. EzrA modulates the frequency and position of FtsZ ring formation. The structure contains 5 spectrin like alpha helical repeats.
Pssm-ID: 428797 [Multi-domain] Cd Length: 542 Bit Score: 46.39 E-value: 9.28e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 201 DDFTNLLEQERERLKKLLEQEKAYQARKEKENAKR-------------LNKLRDELVKLKSF--------ALMLVDERQM 259
Cdd:pfam06160 107 EELDELLESEEKNREEVEELKDKYRELRKTLLANRfsygpaidelekqLAEIEEEFSQFEELtesgdyleAREVLEKLEE 186
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 260 HIEQLGLQSQKVQDLTQKLREE-EEKLKAItsksKEDRQKLLKLEVDFEHKAsrFSQEHEEMNAKLANQESHNRQLRLK- 337
Cdd:pfam06160 187 ETDALEELMEDIPPLYEELKTElPDQLEEL----KEGYREMEEEGYALEHLN--VDKEIQQLEEQLEENLALLENLELDe 260
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 338 ----LVGLTQRIEELEETnknLQK-------AEEELQELRDKIAKGECGNSSLMAEVENLRKR-------VLEMEGKDEE 399
Cdd:pfam06160 261 aeeaLEEIEERIDQLYDL---LEKevdakkyVEKNLPEIEDYLEHAEEQNKELKEELERVQQSytlneneLERVRGLEKQ 337
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 400 ITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSectqlhlNLEKEKNLTKDLLNELEVVKSR 479
Cdd:pfam06160 338 LEELEKRYDEIVERLEEKEVAYSELQEELEEILEQLEEIEEEQEEFKESLQ-------SLRKDELEAREKLDEFKLELRE 410
|
..
gi 585420407 480 VK 481
Cdd:pfam06160 411 IK 412
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
207-366 |
9.79e-05 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 46.55 E-value: 9.79e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 207 LEQERERLKKLLEQ-EKAYQARKEKEN-----------AKRLNKLRDELVKLKSFALMLVDERQMHIEQLG--------- 265
Cdd:COG3206 180 LEEQLPELRKELEEaEAALEEFRQKNGlvdlseeakllLQQLSELESQLAEARAELAEAEARLAALRAQLGsgpdalpel 259
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 266 LQSQKVQDLTQKLREEEEKLKAITSKSKEDRQKLLKLEvdfEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLTQRI 345
Cdd:COG3206 260 LQSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALR---AQIAALRAQLQQEAQRILASLEAELEALQAREASLQAQL 336
|
170 180
....*....|....*....|.
gi 585420407 346 EELEETNKNLQKAEEELQELR 366
Cdd:COG3206 337 AQLEARLAELPELEAELRRLE 357
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
301-678 |
1.10e-04 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 46.50 E-value: 1.10e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 301 KLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLTQRIEELEETNKNLQKAEEELQELRDKIAKgecgnsslm 380
Cdd:pfam02463 155 RLEIEEEAAGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEY--------- 225
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 381 aeVENLRKRVLEMEGKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLE 460
Cdd:pfam02463 226 --LLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELL 303
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 461 KEKNLTKDLLNELEVVKSRVKELecsESRLEKAELSLKDDLTKLKSftvmlVDERKNMMEKIKQEERKVDGLNKNfkvEQ 540
Cdd:pfam02463 304 KLERRKVDDEEKLKESEKEKKKA---EKELKKEKEEIEELEKELKE-----LEIKREAEEEEEEELEKLQEKLEQ---LE 372
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 541 GKVMDVTEKLIEESKKLLKLKSEMEEKVYNLTRERDELIGKLKSEEEKSSELSCSvdllKKRLDGIEEVEREITRGRSRK 620
Cdd:pfam02463 373 EELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKE----ELEILEEEEESIELKQGKLTE 448
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 585420407 621 GSELTCPEDNKIKELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKAN 678
Cdd:pfam02463 449 EKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKAR 506
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
638-760 |
1.23e-04 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 46.16 E-value: 1.23e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 638 EIERLKKRLQQLEVvegdlmktedEYDQLEQKFRTEQDKANFLSQQLEEIKHQIAKnkaiekgEVVSQEAELRHRFRLEE 717
Cdd:COG3206 264 VIQQLRAQLAELEA----------ELAELSARYTPNHPDVIALRAQIAALRAQLQQ-------EAQRILASLEAELEALQ 326
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 585420407 718 AKSRDLKAEVQALKEKIHELMNKEDQLSQLQVDYSVLQQRFME 760
Cdd:COG3206 327 AREASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYES 369
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
432-767 |
1.48e-04 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 46.12 E-value: 1.48e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 432 QKRMSELEKLEEAFSKSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSL-KDDLTKLKSFTVM 510
Cdd:pfam02463 169 RKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLnEERIDLLQELLRD 248
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 511 LVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYNLTRERDEL------IGKLKS 584
Cdd:pfam02463 249 EQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLkesekeKKKAEK 328
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 585 EEEKSSELSCSVDLLKKRLDGIEEVEREITRGRSRKGSELTCPEDNKIKELTLEIERLKKRLQQLEVVEGDLMKTEDEYD 664
Cdd:pfam02463 329 ELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQ 408
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 665 QLEQKFRTEQDKANFLSQQLEEIKHQIAKNKAIEKGEVVSQEAELRHRFRLEEAKSRDLK-AEVQALKEKIHELMNKEDQ 743
Cdd:pfam02463 409 LLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKkSEDLLKETQLVKLQEQLEL 488
|
330 340
....*....|....*....|....
gi 585420407 744 LSQLQVDYSVLQQRFMEEENKNKN 767
Cdd:pfam02463 489 LLSRQKLEERSQKESKARSGLKVL 512
|
|
| CortBP2 |
pfam09727 |
Cortactin-binding protein-2; This entry is the first approximately 250 residues of ... |
398-516 |
1.89e-04 |
|
Cortactin-binding protein-2; This entry is the first approximately 250 residues of cortactin-binding protein 2. In addition to being a positional candidate for autism this protein is expressed at highest levels in the brain in humans. The human protein has six associated ankyrin repeat domains pfam00023 towards the C-terminus which act as protein-protein interaction domains.
Pssm-ID: 462860 [Multi-domain] Cd Length: 187 Bit Score: 43.74 E-value: 1.89e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 398 EEITKTESQCRELRKKLQEeehhskeLRLEVEKLQKRMS---ELEKLEEAFSKSKSECTQLHLNLEKEKnltkdLLNELE 474
Cdd:pfam09727 80 AELEKLVEKQRETQRRMLE-------QLAAAEKRHRRVIrelEEEKRKHARDTAQGDDFTYLLEKERER-----LKQELE 147
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 585420407 475 VVKSRVKELEcseSRLEKAELSLKDDLTKLKSFTVMLVDERK 516
Cdd:pfam09727 148 QEKAQQKRLE---KELKKLLEKLEEELSKQKQIALLLVKERK 186
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
205-420 |
2.01e-04 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 45.39 E-value: 2.01e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 205 NLLEQERERLKKLLEQEKAyqarKEKENAKRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEK 284
Cdd:PHA02562 191 DHIQQQIKTYNKNIEEQRK----KNGENIARKQNKYDELVEEAKTIKAEIEELTDELLNLVMDIEDPSAALNKLNTAAAK 266
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 285 LKAitskskeDRQKLLKLEVDFE--HKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLTQRIEELEETNKNLQKAEEEL 362
Cdd:PHA02562 267 IKS-------KIEQFQKVIKMYEkgGVCPTCTQQISEGPDRITKIKDKLKELQHSLEKLDTAIDELEEIMDEFNEQSKKL 339
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 585420407 363 QELRDKIAKGECGNSSLMAEVENLRKRVLEMEG----KDEEITKTESQCRELRKKLQE---EEHH 420
Cdd:PHA02562 340 LELKNKISTNKQSLITLVDKAKKVKAAIEELQAefvdNAEELAKLQDELDKIVKTKSElvkEKYH 404
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
215-440 |
2.19e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 45.53 E-value: 2.19e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 215 KKLLEQEKAYQARKEKENAKRLNKLRDELVKLKSFALMLVDErqmHIEQLGLQSQKVQDLTQKLREEEEKLKaiTSKSKE 294
Cdd:COG4717 296 EKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPE---ELLELLDRIEELQELLREAEELEEELQ--LEELEQ 370
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 295 DRQKLLKL-----EVDFEHKASRFSQEHE------EMNAKLANQESHNRQLrLKLVGLTQRIEELEETNKNLQKAEEELQ 363
Cdd:COG4717 371 EIAALLAEagvedEEELRAALEQAEEYQElkeeleELEEQLEELLGELEEL-LEALDEEELEEELEELEEELEELEEELE 449
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 585420407 364 ELRDKIAKgecgnsslmaevenLRKRVLEMEgKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEK 440
Cdd:COG4717 450 ELREELAE--------------LEAELEQLE-EDGELAELLQELEELKAELRELAEEWAALKLALELLEEAREEYRE 511
|
|
| Crescentin |
pfam19220 |
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament ... |
315-731 |
2.61e-04 |
|
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament proteins, named crescentin, whose cytoskeletal function is required for the vibrioid and helical shapes of Caulobacter crescentus. Without crescentin, the cells adopt a straight-rod morphology. Crescentin has characteriztic features of IF proteins including the ability to assemble into filaments in vitro without energy or cofactor requirements. In vivo, crescentin forms a helical structure that colocalizes with the inner cell curvatures beneath the cytoplasmic membrane.
Pssm-ID: 437057 [Multi-domain] Cd Length: 401 Bit Score: 45.06 E-value: 2.61e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 315 QEHEEMNAKLANQESHNRQLRLKLVGLTQRIEELEETNKNLQKAEEELQELRDKIAKGECGNSSLMAEVENLRKRVLEME 394
Cdd:pfam19220 3 QRNELLRVRLGEMADRLEDLRSLKADFSQLIEPIEAILRELPQAKSRLLELEALLAQERAAYGKLRRELAGLTRRLSAAE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 395 GkdeEITKTESQCRELRKKLQEEEHHSKELRLEvekLQKRMSELEKLEeafsksksecTQLHLNLEKEKNLT---KDLLN 471
Cdd:pfam19220 83 G---ELEELVARLAKLEAALREAEAAKEELRIE---LRDKTAQAEALE----------RQLAAETEQNRALEeenKALRE 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 472 ELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSftvmLVDErknMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLI 551
Cdd:pfam19220 147 EAQAAEKALQRAEGELATARERLALLEQENRRLQA----LSEE---QAAELAELTRRLAELETQLDATRARLRALEGQLA 219
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 552 EESKKLLKLKSEMEEKVYNLTRERDELigklkseeeksselSCSVDLLKKRLDGIEEVEREiTRGRSRKGSELTCPEDNK 631
Cdd:pfam19220 220 AEQAERERAEAQLEEAVEAHRAERASL--------------RMKLEALTARAAATEQLLAE-ARNQLRDRDEAIRAAERR 284
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 632 IKELTLEIERLKKRlqqLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEeikhqiAKNKAIEKGE-----VVSQE 706
Cdd:pfam19220 285 LKEASIERDTLERR---LAGLEADLERRTQQFQEMQRARAELEERAEMLTKALA------AKDAALERAEeriasLSDRI 355
|
410 420
....*....|....*....|....*....
gi 585420407 707 AELRHRFRLE----EAKSRDLKAEVQALK 731
Cdd:pfam19220 356 AELTKRFEVEraalEQANRRLKEELQRER 384
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
158-484 |
3.71e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 44.76 E-value: 3.71e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 158 EEKQKETYRRMLEQLLLAEKCHRRTVYELENEKHKHTDYmNKSDDFTNLLEQERERLKKLLEQEKAYQARKEKENA--KR 235
Cdd:COG4717 93 LQEELEELEEELEELEAELEELREELEKLEKLLQLLPLY-QELEALEAELAELPERLEELEERLEELRELEEELEEleAE 171
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 236 LNKLRDELV-KLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAITSK---------SKEDRQKLLKLEVD 305
Cdd:COG4717 172 LAELQEELEeLLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEEleqleneleAAALEERLKEARLL 251
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 306 F-----------------------------------------EHKASRFSQEHEEMNAKLANQESHNRQLR--LKLVGLT 342
Cdd:COG4717 252 LliaaallallglggsllsliltiagvlflvlgllallflllAREKASLGKEAEELQALPALEELEEEELEelLAALGLP 331
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 343 ------------QRIEELEETNKNLQKAEEELQ--ELRDKIAK--GECGNSSLmAEVENLRKRVLEMEGKDEEITKTESQ 406
Cdd:COG4717 332 pdlspeellellDRIEELQELLREAEELEEELQleELEQEIAAllAEAGVEDE-EELRAALEQAEEYQELKEELEELEEQ 410
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 407 CRELRKKLQE--EEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLEKEKNLTkDLLNELEVVKSRVKELE 484
Cdd:COG4717 411 LEELLGELEEllEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEEDGELA-ELLQELEELKAELRELA 489
|
|
| COG1340 |
COG1340 |
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]; |
195-451 |
3.86e-04 |
|
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 43.75 E-value: 3.86e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 195 DYMNKSDDFTNLLEQERERLKKLLEQEKAYQARKEKENAKrLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDL 274
Cdd:COG1340 12 ELEEKIEELREEIEELKEKRDELNEELKELAEKRDELNAQ-VKELREEAQELREKRDELNEKVKELKEERDELNEKLNEL 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 275 TQKLREEEEKLKAITSKS---KEDRQKLLKLEVDFEHKASRFSQEheemnaklanqeshnRQLRLKLVGLTQRIEELE-- 349
Cdd:COG1340 91 REELDELRKELAELNKAGgsiDKLRKEIERLEWRQQTEVLSPEEE---------------KELVEKIKELEKELEKAKka 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 350 -ETNKNLQKAEEELQELRDKIAKGECGNSSLMAEVENLRKRVLEMEGKDEEITK----TESQCRELRKKLQEEEHHSKEL 424
Cdd:COG1340 156 lEKNEKLKELRAELKELRKEAEEIHKKIKELAEEAQELHEEMIELYKEADELRKeadeLHKEIVEAQEKADELHEEIIEL 235
|
250 260
....*....|....*....|....*..
gi 585420407 425 RLEVEKLQKRMSELEKLEEAFSKSKSE 451
Cdd:COG1340 236 QKELRELRKELKKLRKKQRALKREKEK 262
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
256-417 |
5.05e-04 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 44.56 E-value: 5.05e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 256 ERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAITSKSKEDRQKLLKLEvDFEHKASRFSQEHEEMNAKLANQESHNRQLR 335
Cdd:COG3096 506 SQQALAQRLQQLRAQLAELEQRLRQQQNAERLLEEFCQRIGQQLDAAE-ELEELLAELEAQLEELEEQAAEAVEQRSELR 584
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 336 LKLVGLTQRIEELEETNKNLQKAEEELQELRDKIakGECGNSSlmAEVENLRKRVLEMEgkdEEITKTESQCRELRKKLQ 415
Cdd:COG3096 585 QQLEQLRARIKELAARAPAWLAAQDALERLREQS--GEALADS--QEVTAAMQQLLERE---REATVERDELAARKQALE 657
|
..
gi 585420407 416 EE 417
Cdd:COG3096 658 SQ 659
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
132-758 |
5.14e-04 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 44.44 E-value: 5.14e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 132 RDAIlAQEKSIGEDVYEKPISELDRLEEKQKETYRRmlEQLLLAEKchrrtvyeLENEKHKHTDYMNKSDDFTNLlEQER 211
Cdd:pfam12128 403 REAR-DRQLAVAEDDLQALESELREQLEAGKLEFNE--EEYRLKSR--------LGELKLRLNQATATPELLLQL-ENFD 470
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 212 ERLKKLleQEKAYQARKEKENAKR----LNKLRDELVKLKSFALMLVDERQMHIEQLGLQ-SQKVQDLTQKLREEEEKLK 286
Cdd:pfam12128 471 ERIERA--REEQEAANAEVERLQSelrqARKRRDQASEALRQASRRLEERQSALDELELQlFPQAGTLLHFLRKEAPDWE 548
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 287 AITSKSKeDRQKLLKLEVDFEHKASRFSQEHEEMNAKLanqeshnrqlRLKLVGLTQRIEELEETNKNLQKAEEELQELR 366
Cdd:pfam12128 549 QSIGKVI-SPELLHRTDLDPEVWDGSVGGELNLYGVKL----------DLKRIDVPEWAASEEELRERLDKAEEALQSAR 617
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 367 DKIAKGECGNSSLMAEVENLRKRvlemegkdEEITKTESQCRELRKKlqeeehhskelRLEVEKlqkrMSELEKLEEAFS 446
Cdd:pfam12128 618 EKQAAAEEQLVQANGELEKASRE--------ETFARTALKNARLDLR-----------RLFDEK----QSEKDKKNKALA 674
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 447 KSKSECTQLHLNLEKEKNLtkdLLNELEVVKSRVKElECSESRLEKAELSLkddltklksftvMLVDERKNMMEKIKQEe 526
Cdd:pfam12128 675 ERKDSANERLNSLEAQLKQ---LDKKHQAWLEEQKE-QKREARTEKQAYWQ------------VVEGALDAQLALLKAA- 737
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 527 rkVDGLNKNFKVEQgkvmdvtEKLIEESKKLLKLKSEMEEKVYNLTRERDELIgklkseeeksselscsvdllkKRLDGI 606
Cdd:pfam12128 738 --IAARRSGAKAEL-------KALETWYKRDLASLGVDPDVIAKLKREIRTLE---------------------RKIERI 787
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 607 EEVEREITRGR---------SRKGSELTCPEDN-KIKELTLEIERL----KKRLQQLEVVEGDLMKTEDEYDQLEQKFRT 672
Cdd:pfam12128 788 AVRRQEVLRYFdwyqetwlqRRPRLATQLSNIErAISELQQQLARLiadtKLRRAKLEMERKASEKQQVRLSENLRGLRC 867
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 673 EQDKANFLS--QQLEEIKHQIAKN-------KAIEKGEVVSQEAELRHRFRLEEAKSRDLKAEV-QALKEKIHELMNKED 742
Cdd:pfam12128 868 EMSKLATLKedANSEQAQGSIGERlaqledlKLKRDYLSESVKKYVEHFKNVIADHSGSGLAETwESLREEDHYQNDKGI 947
|
650
....*....|....*.
gi 585420407 743 QLSQLQVDYSVLQQRF 758
Cdd:pfam12128 948 RLLDYRKLVPYLEQWF 963
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
268-484 |
5.75e-04 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 44.24 E-value: 5.75e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 268 SQKVQDLTQKLREEEEKLKAITSKSKEdrqkllkleVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLTQRIEE 347
Cdd:COG3206 181 EEQLPELRKELEEAEAALEEFRQKNGL---------VDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGS 251
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 348 LEETNKNLQkAEEELQELRDKIAKgecgnssLMAEVENLRKRVLE----MEGKDEEITKTESQCR-ELRKKLQEEEHHSK 422
Cdd:COG3206 252 GPDALPELL-QSPVIQQLRAQLAE-------LEAELAELSARYTPnhpdVIALRAQIAALRAQLQqEAQRILASLEAELE 323
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 585420407 423 ELRLEVEKLQKRMSELEKLEEAFSKSKSEctqlHLNLEKEKNLTKDLLNELEvvkSRVKELE 484
Cdd:COG3206 324 ALQAREASLQAQLAQLEARLAELPELEAE----LRRLEREVEVARELYESLL---QRLEEAR 378
|
|
| CCDC22 |
pfam05667 |
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ... |
209-468 |
5.94e-04 |
|
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.
Pssm-ID: 461708 [Multi-domain] Cd Length: 600 Bit Score: 43.86 E-value: 5.94e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 209 QERERLKKLLEQEKAYQARKEKENAKRLNKLRDELVKLksfaLMLVDERQMHIEQLGLQSQ--KVQDLT-QKLREEEEKL 285
Cdd:pfam05667 243 RKRTKLLKRIAEQLRSAALAGTEATSGASRSAQDLAEL----LSSFSGSSTTDTGLTKGSRftHTEKLQfTNEAPAATSS 318
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 286 KAITSKSKEDRQKLLKLEVD-FEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLTQRIEELEETNKNLQKAEEELQE 364
Cdd:pfam05667 319 PPTKVETEEELQQQREEELEeLQEQLEDLESSIQELEKEIKKLESSIKQVEEELEELKEQNEELEKQYKVKKKTLDLLPD 398
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 365 LRDKIAKgecgnssLMAEVENLRKRVLEMEGKDEEITKTE-SQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEklEE 443
Cdd:pfam05667 399 AEENIAK-------LQALVDASAQRLVELAGQWEKHRVPLiEEYRALKEAKSNKEDESQRKLEEIKELREKIKEVA--EE 469
|
250 260
....*....|....*....|....*.
gi 585420407 444 AFSKSksectQLHLNLEKE-KNLTKD 468
Cdd:pfam05667 470 AKQKE-----ELYKQLVAEyERLPKD 490
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
47-453 |
5.96e-04 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 44.19 E-value: 5.96e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 47 RKEDDVMASGTVKRHLKTSGECERKTKKSLELSKEDLIQLLSIMEGELQAREDVIHMLktekTKPEVLEAHYGSAEPEKV 126
Cdd:TIGR00618 532 RGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNL----QNITVRLQDLTEKLSEAE 607
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 127 LRVLHRDAILAQEKSIGEDVYEKpiseldRLEEKQKETYrrmlEQLLLAEKchrrTVYELENEKHKHTDYMNKSDDFTNL 206
Cdd:TIGR00618 608 DMLACEQHALLRKLQPEQDLQDV------RLHLQQCSQE----LALKLTAL----HALQLTLTQERVREHALSIRVLPKE 673
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 207 LEQERERLKKLLEQEKAYQARKEKENAKRLNKLRDELVKLKSFalmlvdERQMHIEQLGLQSQKvqdltQKLREEEEKLK 286
Cdd:TIGR00618 674 LLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEY------DREFNEIENASSSLG-----SDLAAREDALN 742
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 287 AITSKSKEDRQKLLKLEVDFEHKASrfsqEHEEMNAKLANQESHNRQlrlklvGLTQRIEELEETNKNLQKAEEEL-QEL 365
Cdd:TIGR00618 743 QSLKELMHQARTVLKARTEAHFNNN----EEVTAALQTGAELSHLAA------EIQFFNRLREEDTHLLKTLEAEIgQEI 812
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 366 RDKIAKGECGNSSLMAEVENLRKRVLEMEGKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQ-KRMSELEKLEEA 444
Cdd:TIGR00618 813 PSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLSDKLNgINQIKIQFDGDA 892
|
....*....
gi 585420407 445 FSKSKSECT 453
Cdd:TIGR00618 893 LIKFLHEIT 901
|
|
| COG1340 |
COG1340 |
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]; |
254-527 |
6.67e-04 |
|
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 43.36 E-value: 6.67e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 254 VDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAITSKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQ 333
Cdd:COG1340 3 TDELSSSLEELEEKIEELREEIEELKEKRDELNEELKELAEKRDELNAQVKELREEAQELREKRDELNEKVKELKEERDE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 334 LRLKLVGLTQRIEELEETNKNLQKAEEELQELRDKIAKGE--CGNSSL-----------MAEVENLRKRVLEMEGKDEEI 400
Cdd:COG1340 83 LNEKLNELREELDELRKELAELNKAGGSIDKLRKEIERLEwrQQTEVLspeeekelvekIKELEKELEKAKKALEKNEKL 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 401 TKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSEctqLHLNLEKEKNLTKDLLNELEVVKSRV 480
Cdd:COG1340 163 KELRAELKELRKEAEEIHKKIKELAEEAQELHEEMIELYKEADELRKEADE---LHKEIVEAQEKADELHEEIIELQKEL 239
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 585420407 481 KELECSESRLEKAELSLKDDLTKLKSFtvmlvDERKNMMEKIKQEER 527
Cdd:COG1340 240 RELRKELKKLRKKQRALKREKEKEELE-----EKAEEIFEKLKKGEK 281
|
|
| CagA_N |
pfam18971 |
CagA protein; The Helicobacter pylori type IV secretion effector CagA is a major bacterial ... |
202-578 |
7.57e-04 |
|
CagA protein; The Helicobacter pylori type IV secretion effector CagA is a major bacterial virulence determinant and critical for gastric carcinogenesis. X-ray crystallographic analysis of the N-terminal CagA fragment (residues 1-876) revealed that the region has a structure comprised of three discrete domains. Domain I constitutes a mobile CagA N terminus, while Domain II tethers CagA to the plasma membrane by interacting with membrane phosphatidylserine. Domain III interacts intramolecularly with the intrinsically disordered C-terminal region, and this interaction potentiates the pathogenic scaffold/hub function of CagA.
Pssm-ID: 408741 [Multi-domain] Cd Length: 876 Bit Score: 43.99 E-value: 7.57e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 202 DFTNLLEQERERLKKLleqekayqarKEKENAKRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKV------QDLT 275
Cdd:pfam18971 403 DFMEFLAQNNTKLDNL----------SEKEKEKFQNEIEDFQKDSKAYLDALGNDRIAFVSKKDTKHSALitefnnGDLS 472
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 276 QKLREEEEKlkaitSKSKEDRQKLLKLEVDFEHKASRFSqehEEMNAKLANQESHNRqlrlKLVGLTQRIEELEE----- 350
Cdd:pfam18971 473 YTLKDYGKK-----ADKALDREKNVTLQGSLKHDGVMFV---DYSNFKYTNASKNPN----KGVGATNGVSHLEAgfnkv 540
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 351 ----------------TNKNLQKAEE----ELQELRDKIAKGECGNSSLMAEVENLRKRVLEME--GKDEEITKTEsqcR 408
Cdd:pfam18971 541 avfnlpdlnnlaitsfVRRNLENKLTakglSLQEANKLIKDFLSSNKELAGKALNFNKAVAEAKstGNYDEVKKAQ---K 617
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 409 ELRKKLQEEEHHSKELRlevEKLQKRMSELEKLeEAFSKSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELecsES 488
Cdd:pfam18971 618 DLEKSLRKREHLEKEVE---KKLESKSGNKNKM-EAKAQANSQKDEIFALINKEANRDARAIAYTQNLKGIKREL---SD 690
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 489 RLEKAELSLKDdltKLKSFtvmlvDERKNmmekikqeerkvdGLNKNF-KVEQgkvmdvTEKLIEESKKLLKLKSEMEEK 567
Cdd:pfam18971 691 KLEKISKDLKD---FSKSF-----DEFKN-------------GKNKDFsKAEE------TLKALKGSVKDLGINPEWISK 743
|
410
....*....|.
gi 585420407 568 VYNLTRERDEL 578
Cdd:pfam18971 744 VENLNAALNEF 754
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
75-745 |
8.14e-04 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 43.90 E-value: 8.14e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 75 SLELSKEDLIQLLSIMEGELQAREDVIHMLKTE----------KTKPEVLEAHYGSAEPEKVLRVLHRDAILAQEKSIGE 144
Cdd:TIGR02169 248 SLEEELEKLTEEISELEKRLEEIEQLLEELNKKikdlgeeeqlRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKL 327
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 145 DV----YEKPISELDRleekQKETYRRMLEQlLLAEKCHRRTVYElenekhkhtdymnksdDFTNLLEQERERLKKLLEQ 220
Cdd:TIGR02169 328 EAeidkLLAEIEELER----EIEEERKRRDK-LTEEYAELKEELE----------------DLRAELEEVDKEFAETRDE 386
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 221 EKAYQarkekenaKRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAITSKSKEDRQKLL 300
Cdd:TIGR02169 387 LKDYR--------EKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLE 458
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 301 KLEVDFEhkasRFSQEHEEMNAKLANQESHNRQLRLKLVGLTQRIEELEETNKNLQKAEEELQELRdkiaKGECGNSSLM 380
Cdd:TIGR02169 459 QLAADLS----KYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASI----QGVHGTVAQL 530
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 381 AEVENLRKRVLEMEG---------KDEEITKtesQCRELRK-------------KLQEEEHHSKELRLE----------- 427
Cdd:TIGR02169 531 GSVGERYATAIEVAAgnrlnnvvvEDDAVAK---EAIELLKrrkagratflplnKMRDERRDLSILSEDgvigfavdlve 607
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 428 ------------------VEKL--------QKRMSELEKleEAFSKSKSeCTQLHLNLEKEKNLTKDLLNELEVVKSRVK 481
Cdd:TIGR02169 608 fdpkyepafkyvfgdtlvVEDIeaarrlmgKYRMVTLEG--ELFEKSGA-MTGGSRAPRGGILFSRSEPAELQRLRERLE 684
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 482 ELECSESRL--EKAEL-SLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLL 558
Cdd:TIGR02169 685 GLKRELSSLqsELRRIeNRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELE 764
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 559 KLKSEMEEKVYNLTRErdeligklkseeeksselscsvdllkkrldgIEEVEREITRGRSRKgseltcpEDNKIKELTLE 638
Cdd:TIGR02169 765 ARIEELEEDLHKLEEA-------------------------------LNDLEARLSHSRIPE-------IQAELSKLEEE 806
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 639 IERLKKRLQQLevvEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQIAKNKAiEKGEVVSQEAELRHRFRLEEA 718
Cdd:TIGR02169 807 VSRIEARLREI---EQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNG-KKEELEEELEELEAALRDLES 882
|
730 740
....*....|....*....|....*..
gi 585420407 719 KSRDLKAEVQALKEKIHELMNKEDQLS 745
Cdd:TIGR02169 883 RLGDLKKERDELEAQLRELERKIEELE 909
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
599-780 |
9.02e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 43.75 E-value: 9.02e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 599 LKKRLDGIEEVEREITRGRSRKGSELtcpEDNKIKELTLEIERLKKRLQQLEVVEGDLmktEDEYDQLEQKFRTEQdkan 678
Cdd:COG4913 267 ARERLAELEYLRAALRLWFAQRRLEL---LEAELEELRAELARLEAELERLEARLDAL---REELDELEAQIRGNG---- 336
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 679 flSQQLEEIKHQIAKNKAiEKGEVVSQEAELRHRFR---LEEAKSRD----LKAEVQALKEKIHELMNK--------EDQ 743
Cdd:COG4913 337 --GDRLEQLEREIERLER-ELEERERRRARLEALLAalgLPLPASAEefaaLRAEAAALLEALEEELEAleealaeaEAA 413
|
170 180 190
....*....|....*....|....*....|....*..
gi 585420407 744 LSQLQVDYSVLQQRFMEEENKNKNMGQEVLNLTKELE 780
Cdd:COG4913 414 LRDLRRELRELEAEIASLERRKSNIPARLLALRDALA 450
|
|
| ADIP |
pfam11559 |
Afadin- and alpha -actinin-Binding; This family is found in mammals where it is localized at ... |
428-532 |
9.50e-04 |
|
Afadin- and alpha -actinin-Binding; This family is found in mammals where it is localized at cell-cell adherens junctions, and in Sch. pombe and other fungi where it anchors spindle-pole bodies to spindle microtubules. It is a coiled-coil structure, and in pombe, it is required for anchoring the minus end of spindle microtubules to the centrosome equivalent, the spindle-pole body. The name ADIP derives from the family being composed of Afadin- and alpha -Actinin-Binding Proteins localized at Cell-Cell Adherens Junctions.
Pssm-ID: 463295 [Multi-domain] Cd Length: 151 Bit Score: 41.15 E-value: 9.50e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 428 VEKLQKRMSELEKLEEAFSKSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSf 507
Cdd:pfam11559 44 LQQRDRDLEFRESLNETIRTLEAEIERLQSKIERLKTQLEDLERELALLQAKERQLEKKLKTLEQKLKNEKEELQRLKN- 122
|
90 100
....*....|....*....|....*
gi 585420407 508 tvMLVDERKNMMEKIKQEERKVDGL 532
Cdd:pfam11559 123 --ALQQIKTQFAHEVKKRDREIEKL 145
|
|
| PLN02939 |
PLN02939 |
transferase, transferring glycosyl groups |
265-556 |
1.02e-03 |
|
transferase, transferring glycosyl groups
Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 43.35 E-value: 1.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 265 GLQSQKVQDLTQKLREEEEK---LKAITSKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNA--KLANQE-SHNRQLRLKL 338
Cdd:PLN02939 124 QLSDFQLEDLVGMIQNAEKNillLNQARLQALEDLEKILTEKEALQGKINILEMRLSETDAriKLAAQEkIHVEILEEQL 203
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 339 VGLTQRIEELEETNKNLQKA-EEELQELRDKiakgecgNSSLMAEVENLRKRVLEMEGKDEEITKTESQCRELRKKLQEE 417
Cdd:PLN02939 204 EKLRNELLIRGATEGLCVHSlSKELDVLKEE-------NMLLKDDIQFLKAELIEVAETEERVFKLEKERSLLDASLREL 276
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 418 EHHSKELRLEVEKLQKR-----MSELEKLEEAFSKSKSECTQLHLNLEKEKnltkDLLNELEVVKSRVKELECSESRLEK 492
Cdd:PLN02939 277 ESKFIVAQEDVSKLSPLqydcwWEKVENLQDLLDRATNQVEKAALVLDQNQ----DLRDKVDKLEASLKEANVSKFSSYK 352
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 585420407 493 AELSLKddltKLKsftvmLVDERknmMEKIKQEERKVDGLNKNFKVEqgkVMDVTEKLIEESKK 556
Cdd:PLN02939 353 VELLQQ----KLK-----LLEER---LQASDHEIHSYIQLYQESIKE---FQDTLSKLKEESKK 401
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
207-578 |
1.13e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 43.22 E-value: 1.13e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 207 LEQERERLKKLLEQEKAYQARKEK---------ENAKRLNKLRDELVKLKSF--ALMLVDERQMHIEQLGLQSQKVQDLT 275
Cdd:COG4717 73 LKELEEELKEAEEKEEEYAELQEEleeleeeleELEAELEELREELEKLEKLlqLLPLYQELEALEAELAELPERLEELE 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 276 QKLREEEEKLKAITSKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLTQRIEELEETNKNL 355
Cdd:COG4717 153 ERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQL 232
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 356 QKaEEELQELRDKIAKGE---------CGNSSLMAEVENLRKRVLEMEGKDEEITKTESQCRELRKKLQEEEHHSKELRL 426
Cdd:COG4717 233 EN-ELEAAALEERLKEARlllliaaalLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALP 311
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 427 EVEKLQKRmsELEKLEEAFSKSKSECTQLHLNLEKEKNLTKDLLNELEvvkSRVKELECSESRLEKAELSLKDDLTKLKS 506
Cdd:COG4717 312 ALEELEEE--ELEELLAALGLPPDLSPEELLELLDRIEELQELLREAE---ELEEELQLEELEQEIAALLAEAGVEDEEE 386
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 585420407 507 FT--VMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVmdVTEKLIEESKKLLKLKSEMEEKVYNLTRERDEL 578
Cdd:COG4717 387 LRaaLEQAEEYQELKEELEELEEQLEELLGELEELLEAL--DEEELEEELEELEEELEELEEELEELREELAEL 458
|
|
| COG1340 |
COG1340 |
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]; |
511-750 |
1.14e-03 |
|
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 42.59 E-value: 1.14e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 511 LVDERKNMMEKIKQEERKVDGLN---KNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYNLTRERDELIGKLKSEEE 587
Cdd:COG1340 13 LEEKIEELREEIEELKEKRDELNeelKELAEKRDELNAQVKELREEAQELREKRDELNEKVKELKEERDELNEKLNELRE 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 588 KSSELSCSVDLLKKRLDGIEEVEREITRGRSRKGSELTCPED-----NKIKELTLEIERLKKRLQQLEvvegDLMKTEDE 662
Cdd:COG1340 93 ELDELRKELAELNKAGGSIDKLRKEIERLEWRQQTEVLSPEEekelvEKIKELEKELEKAKKALEKNE----KLKELRAE 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 663 YDQLEQKFRTEQDKANFLSQQLEEIKHQIAKNKaiEKGEVVSQEA-ELRHRFRLEEAKSRDLKAEVQALKEKIHELMNKE 741
Cdd:COG1340 169 LKELRKEAEEIHKKIKELAEEAQELHEEMIELY--KEADELRKEAdELHKEIVEAQEKADELHEEIIELQKELRELRKEL 246
|
....*....
gi 585420407 742 DQLSQLQVD 750
Cdd:COG1340 247 KKLRKKQRA 255
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
538-790 |
1.18e-03 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 43.12 E-value: 1.18e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 538 VEQGKVMDVTE-------KLIEESKKLLKLKSEMEEKVYNLTRERDELigklkseeeksselscsvdllkKRLDGI-EEV 609
Cdd:TIGR02168 141 IEQGKISEIIEakpeerrAIFEEAAGISKYKERRKETERKLERTRENL----------------------DRLEDIlNEL 198
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 610 EREItrGRSRKGSELTcpedNKIKELTLEIERLKKRLQQLEVVE--GDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEEI 687
Cdd:TIGR02168 199 ERQL--KSLERQAEKA----ERYKELKAELRELELALLVLRLEElrEELEELQEELKEAEEELEELTAELQELEEKLEEL 272
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 688 KHQIAK-------------NKAIEKGEVVSQEAELRHRFRLEEAKSRDLKAEVQALKEKIHELMNK----EDQLSQLQVD 750
Cdd:TIGR02168 273 RLEVSEleeeieelqkelyALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEElaelEEKLEELKEE 352
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 585420407 751 YSVLQQRFMEEENKNKNMGQEVLNLTKELE-LSKRYSRALR 790
Cdd:TIGR02168 353 LESLEAELEELEAELEELESRLEELEEQLEtLRSKVAQLEL 393
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
631-788 |
1.47e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 42.44 E-value: 1.47e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 631 KIKELTLEIERLKKRLQQLE----VVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQIAK--------NKAIE 698
Cdd:COG4942 42 ELAALKKEEKALLKQLAALErriaALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAEllralyrlGRQPP 121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 699 KGEVVSQE--AELRHRFRLEEAKSRDLKAEVQALKEKIHELMNKEDQLSQLQVDYSVLQQRFMEEENKNKNMGQEVLNLT 776
Cdd:COG4942 122 LALLLSPEdfLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLL 201
|
170
....*....|..
gi 585420407 777 KELELSKRYSRA 788
Cdd:COG4942 202 ARLEKELAELAA 213
|
|
| EzrA |
pfam06160 |
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like ... |
343-693 |
1.55e-03 |
|
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like cell-division protein FtsZ polymerizes into a ring structure that establishes the location of the nascent division site. EzrA modulates the frequency and position of FtsZ ring formation. The structure contains 5 spectrin like alpha helical repeats.
Pssm-ID: 428797 [Multi-domain] Cd Length: 542 Bit Score: 42.53 E-value: 1.55e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 343 QRIEELEETNK--NLQKAEEELQELRDKIAKGEcgnsslmAEVENLRKRVLEMEGKDE----EITKTESQCRELRKKLQE 416
Cdd:pfam06160 67 ELLFEAEELNDkyRFKKAKKALDEIEELLDDIE-------EDIKQILEELDELLESEEknreEVEELKDKYRELRKTLLA 139
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 417 EEHHSKELrleVEKLQKRMSELEKLEEAFSKSKSECtqlhlNLEKEKNLTKDLLNELEVVKSRVKELEcseSRLEKAELS 496
Cdd:pfam06160 140 NRFSYGPA---IDELEKQLAEIEEEFSQFEELTESG-----DYLEAREVLEKLEEETDALEELMEDIP---PLYEELKTE 208
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 497 LKDDLTKLKS-FTVMLVD----ERKNMMEKIKQEERKVDGLNKNfkVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVY-- 569
Cdd:pfam06160 209 LPDQLEELKEgYREMEEEgyalEHLNVDKEIQQLEEQLEENLAL--LENLELDEAEEALEEIEERIDQLYDLLEKEVDak 286
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 570 -NLTRERDELIGKLKSEEEKSSELSCSVDLLKKRLdGIEEVEREITRGRSRKGSELtcpeDNKIKELTLEI--------- 639
Cdd:pfam06160 287 kYVEKNLPEIEDYLEHAEEQNKELKEELERVQQSY-TLNENELERVRGLEKQLEEL----EKRYDEIVERLeekevayse 361
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 585420407 640 --ERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQIAK 693
Cdd:pfam06160 362 lqEELEEILEQLEEIEEEQEEFKESLQSLRKDELEAREKLDEFKLELREIKRLVEK 417
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
467-784 |
1.61e-03 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 42.70 E-value: 1.61e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 467 KDLLNELEVVKsrvKELECSESRLEKAELSLKDDLTKLKSFTV---MLVDERKNMMEKIKQEERKVDGLNKN---FKVEQ 540
Cdd:TIGR04523 36 KQLEKKLKTIK---NELKNKEKELKNLDKNLNKDEEKINNSNNkikILEQQIKDLNDKLKKNKDKINKLNSDlskINSEI 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 541 GKVMDVTEKLIEESKKLLKLKSEMEEKVY-------NLTRERDELIGKLKSEEEKSSELSCSVDLLKKRLDGIEEVEREI 613
Cdd:TIGR04523 113 KNDKEQKNKLEVELNKLEKQKKENKKNIDkflteikKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKI 192
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 614 TRGRSRKGSELTCPE--DNKIKELTLEIERLKKRLQQLEvveGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQI 691
Cdd:TIGR04523 193 KNKLLKLELLLSNLKkkIQKNKSLESQISELKKQNNQLK---DNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQL 269
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 692 ---------AKNKAIEKGEVVSQ-EAELRH-RFRLEEAKSRDLKAEVQALKEKIHELMNK----EDQLSQLQVDYSVLQQ 756
Cdd:TIGR04523 270 sekqkeleqNNKKIKELEKQLNQlKSEISDlNNQKEQDWNKELKSELKNQEKKLEEIQNQisqnNKIISQLNEQISQLKK 349
|
330 340
....*....|....*....|....*...
gi 585420407 757 RFMEEENKNKNMGQEVLNLTKELELSKR 784
Cdd:TIGR04523 350 ELTNSESENSEKQRELEEKQNEIEKLKK 377
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
225-788 |
1.62e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 42.98 E-value: 1.62e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 225 QARKEKENAKRLNKLRDELVKLKsfalmlvdERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAITSKSKEDRQKLLKLEV 304
Cdd:COG4913 226 AADALVEHFDDLERAHEALEDAR--------EQIELLEPIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAEL 297
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 305 DfehkasRFSQEHEEMNAKLANQESHNRQLRLKLVGLTQRI-----EELEETNKNLQKAEEELQELRDKIAKgecgnssL 379
Cdd:COG4913 298 E------ELRAELARLEAELERLEARLDALREELDELEAQIrgnggDRLEQLEREIERLERELEERERRRAR-------L 364
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 380 MAEVENLRkrvLEMEGKDEEITKTESQCRELRKKLQEEEHhskelRLEvEKLQKRMSELEKLEEAFSKSKSECTQL---H 456
Cdd:COG4913 365 EALLAALG---LPLPASAEEFAALRAEAAALLEALEEELE-----ALE-EALAEAEAALRDLRRELRELEAEIASLerrK 435
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 457 LNLEKE-KNLTKDLLNELEVVKSRVK------ELECSESR----LEKAelslkddltkLKSF-TVMLVDERKnmmekIKQ 524
Cdd:COG4913 436 SNIPARlLALRDALAEALGLDEAELPfvgeliEVRPEEERwrgaIERV----------LGGFaLTLLVPPEH-----YAA 500
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 525 EERKVDGLNKN-----FKVEQGKVMDVTEKLIEES--KKLLKLKSEMEEKVYNLTRERDELIgklkseeeksselscsvd 597
Cdd:COG4913 501 ALRWVNRLHLRgrlvyERVRTGLPDPERPRLDPDSlaGKLDFKPHPFRAWLEAELGRRFDYV------------------ 562
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 598 llkkRLDGIEEVERE---ITR--------GRSRKGSELTCPEDN--------KIKELTLEIERLKKRLQQLEvveGDLMK 658
Cdd:COG4913 563 ----CVDSPEELRRHpraITRagqvkgngTRHEKDDRRRIRSRYvlgfdnraKLAALEAELAELEEELAEAE---ERLEA 635
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 659 TEDEYDQLEQKFRTEQDKANF---------LSQQLEEIKHQIAknkAIEKG-----EVVSQEAELRHRFRLEEAKSRDLK 724
Cdd:COG4913 636 LEAELDALQERREALQRLAEYswdeidvasAEREIAELEAELE---RLDASsddlaALEEQLEELEAELEELEEELDELK 712
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 585420407 725 AEVQALKEKIHELMNKEDQLSQLQVDYSV---------LQQRFmEEENKNKNMGQEVLNLTKELE-LSKRYSRA 788
Cdd:COG4913 713 GEIGRLEKELEQAEEELDELQDRLEAAEDlarlelralLEERF-AAALGDAVERELRENLEERIDaLRARLNRA 785
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
151-365 |
2.02e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 42.45 E-value: 2.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 151 ISELDRLEEKQKETYRRMLEQLLLAEKCHRRTVYELENEKHKHTDYMNKSDDFTN--LLEQERERLKKLLEQ-------- 220
Cdd:COG4717 307 LQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEelQLEELEQEIAALLAEagvedeee 386
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 221 --EKAYQARKEKENAKRLNKLRDELVKLKSFALMLVDErqmhiEQLGLQSQKVQDLTQKLREEEEKLKAITSKSKEDRQK 298
Cdd:COG4717 387 lrAALEQAEEYQELKEELEELEEQLEELLGELEELLEA-----LDEEELEEELEELEEELEELEEELEELREELAELEAE 461
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 585420407 299 LLKLEVDfeHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLTQRIEELEETNKN--LQKAEEELQEL 365
Cdd:COG4717 462 LEQLEED--GELAELLQELEELKAELRELAEEWAALKLALELLEEAREEYREERLPpvLERASEYFSRL 528
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
462-797 |
2.27e-03 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 42.23 E-value: 2.27e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 462 EKNLT--KDLLNELEvvkSRVKELEcSESrlEKAE--LSLKDDLTKLKSFtvMLVDERKNMMEKIKQEERKVDGLNKNFK 537
Cdd:COG1196 185 EENLErlEDILGELE---RQLEPLE-RQA--EKAEryRELKEELKELEAE--LLLLKLRELEAELEELEAELEELEAELE 256
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 538 VEQGKVMDVTEKLIEESKKLLKLKSEMEEKvynltRERDELIGKLkseeeksselscsvdllkkrldgIEEVEREITRGR 617
Cdd:COG1196 257 ELEAELAELEAELEELRLELEELELELEEA-----QAEEYELLAE-----------------------LARLEQDIARLE 308
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 618 SRkgseltcpednkIKELTLEIERLKKRL-----------QQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEE 686
Cdd:COG1196 309 ER------------RRELEERLEELEEELaeleeeleeleEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAE 376
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 687 IKHQIAK------NKAIEKGEVVSQEAELRHRFRLEEAKSRDLKAEVQALKEKIHELMNKEDQLSQLQVDysvLQQRFME 760
Cdd:COG1196 377 AEEELEElaeellEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEE---AAEEEAE 453
|
330 340 350
....*....|....*....|....*....|....*..
gi 585420407 761 EENKNKNMGQEVLNLTKELELSKRYSRALRPSVNGRR 797
Cdd:COG1196 454 LEEEEEALLELLAELLEEAALLEAALAELLEELAEAA 490
|
|
| HEC1 |
COG5185 |
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ... |
233-738 |
2.35e-03 |
|
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444066 [Multi-domain] Cd Length: 594 Bit Score: 42.25 E-value: 2.35e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 233 AKRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAITSKSKEDRQKLLKLEVDFEHKASR 312
Cdd:COG5185 106 LIKLPNYEWSADILISLLYLYKSEIVALKDELIKVEKLDEIADIEASYGEVETGIIKDIFGKLTQELNQNLKKLEIFGLT 185
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 313 FSQEHEEMNAKLANQEshnrqlrlKLVGLTQRIEELEETNKNLQKAEEELQELRDKIAKGECGNSSLMAEVENLRKRVLE 392
Cdd:COG5185 186 LGLLKGISELKKAEPS--------GTVNSIKESETGNLGSESTLLEKAKEIINIEEALKGFQDPESELEDLAQTSDKLEK 257
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 393 MEGKDEEITktESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHlNLEKEKNLTKDLLNE 472
Cdd:COG5185 258 LVEQNTDLR--LEKLGENAESSKRLNENANNLIKQFENTKEKIAEYTKSIDIKKATESLEEQLA-AAEAEQELEESKRET 334
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 473 LEVVKSRVKELECSESRLEKAELSLKDDLTKLksFTVMLVDERKNMMEKIKQEerkvdgLNKNFKVEQGKVMDVTEKLIE 552
Cdd:COG5185 335 ETGIQNLTAEIEQGQESLTENLEAIKEEIENI--VGEVELSKSSEELDSFKDT------IESTKESLDEIPQNQRGYAQE 406
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 553 ESKKLLKLKSEMEEKVYNLTRERDELIGKLKSEEEKSSELSCSVDLLKKRLDGIE-EVEREITRGRSRKGSELTCPEDNK 631
Cdd:COG5185 407 ILATLEDTLKAADRQIEELQRQIEQATSSNEEVSKLLNELISELNKVMREADEESqSRLEEAYDEINRSVRSKKEDLNEE 486
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 632 IKELTLEIERLKKRLQQLEV-VEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQIAKNKAIEKGEVVSQEAELR 710
Cdd:COG5185 487 LTQIESRVSTLKATLEKLRAkLERQLEGVRSKLDQVAESLKDFMRARGYAHILALENLIPASELIQASNAKTDGQAANLR 566
|
490 500
....*....|....*....|....*...
gi 585420407 711 HRFRLEEAKSRDLKAEVQALKEKIHELM 738
Cdd:COG5185 567 TAVIDELTQYLSTIESQQAREDPIPDQA 594
|
|
| PRK12705 |
PRK12705 |
hypothetical protein; Provisional |
634-743 |
2.46e-03 |
|
hypothetical protein; Provisional
Pssm-ID: 237178 [Multi-domain] Cd Length: 508 Bit Score: 42.00 E-value: 2.46e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 634 ELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQIAKNKAIEKGEVVSQ--EAELRH 711
Cdd:PRK12705 78 ELQREEERLVQKEEQLDARAEKLDNLENQLEEREKALSARELELEELEKQLDNELYRVAGLTPEQARKLLLKllDAELEE 157
|
90 100 110
....*....|....*....|....*....|..
gi 585420407 712 rfrleeaksrDLKAEVQALKEKIHELMNKEDQ 743
Cdd:PRK12705 158 ----------EKAQRVKKIEEEADLEAERKAQ 179
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
207-371 |
2.48e-03 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 42.07 E-value: 2.48e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 207 LEQERERLKKLLEQekayqARKEKENAKRLNKL--RDELVKLKSFALMLVDERQmhieqlglqsQKVQDLTQKLREEEEK 284
Cdd:PRK12704 33 IKEAEEEAKRILEE-----AKKEAEAIKKEALLeaKEEIHKLRNEFEKELRERR----------NELQKLEKRLLQKEEN 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 285 LKAITSKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQeshnRQLRLKLVGLTQR------IEELE-----ETNK 353
Cdd:PRK12704 98 LDRKLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEEQ----LQELERISGLTAEeakeilLEKVEeearhEAAV 173
|
170
....*....|....*...
gi 585420407 354 NLQKAEEELQELRDKIAK 371
Cdd:PRK12704 174 LIKEIEEEAKEEADKKAK 191
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
596-783 |
2.77e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 42.06 E-value: 2.77e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 596 VDLLKKRLDGIEEVEREITRGRSRKgSELtcpeDNKIKELTLEIERLKKRLQQLEVVEgDLMKTEDEYDQLEQKFRTEQD 675
Cdd:COG4717 73 LKELEEELKEAEEKEEEYAELQEEL-EEL----EEELEELEAELEELREELEKLEKLL-QLLPLYQELEALEAELAELPE 146
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 676 KANFLSQQLEEIKHQIAKNKAIEkgevvsQEAElRHRFRLEEAKSRDLKAEVQALKEKIHELMNKEDQLSQLQVDYSVLQ 755
Cdd:COG4717 147 RLEELEERLEELRELEEELEELE------AELA-ELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQ 219
|
170 180
....*....|....*....|....*...
gi 585420407 756 QRFMEEENKNKNMGQEVLNLTKELELSK 783
Cdd:COG4717 220 EELEELEEELEQLENELEAAALEERLKE 247
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
377-578 |
2.81e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 41.67 E-value: 2.81e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 377 SSLMAEVENLRKRVLEMEGKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEK----LEEAFSKSKSEC 452
Cdd:COG4942 13 LAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQelaaLEAELAELEKEI 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 453 TQLHLNLEKEKNLTKDLLNELEVVkSRVKELecsesrleKAELSLKDDLTKLKSFTVM--LVDERKNMMEKIKQEERKVD 530
Cdd:COG4942 93 AELRAELEAQKEELAELLRALYRL-GRQPPL--------ALLLSPEDFLDAVRRLQYLkyLAPARREQAEELRADLAELA 163
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 585420407 531 GLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYNLTRERDEL 578
Cdd:COG4942 164 ALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAEL 211
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
381-873 |
2.83e-03 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 41.81 E-value: 2.83e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 381 AEVENLRKRVLEMEGKDEEITKTESQCRELRKKLQEEEHHSKELR---LEVEKLQKRMSELEKLEEAFSKSKSECTQLHL 457
Cdd:PRK01156 149 AQRKKILDEILEINSLERNYDKLKDVIDMLRAEISNIDYLEEKLKssnLELENIKKQIADDEKSHSITLKEIERLSIEYN 228
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 458 NLEKEKNLTKDLLNEL----EVVKSRVKELECSESRLEKAEL------SLKDDLTKLKSFTVMLVDERKNMMEKIKQEER 527
Cdd:PRK01156 229 NAMDDYNNLKSALNELssleDMKNRYESEIKTAESDLSMELEknnyykELEERHMKIINDPVYKNRNYINDYFKYKNDIE 308
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 528 KVDGLNKNFKVEQGKVMDVTEKLIEESK---KLLKLKSEMEEkvynLTRERDELIGKLKSEEEKSSelscSVDLLKKRld 604
Cdd:PRK01156 309 NKKQILSNIDAEINKYHAIIKKLSVLQKdynDYIKKKSRYDD----LNNQILELEGYEMDYNSYLK----SIESLKKK-- 378
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 605 gIEEVEREITR-----GRSRKGSELTCPEDNKI-KELTLEIERLKKRLQQLEVVEGDLMKTEDEY--------------- 663
Cdd:PRK01156 379 -IEEYSKNIERmsafiSEILKIQEIDPDAIKKElNEINVKLQDISSKVSSLNQRIRALRENLDELsrnmemlngqsvcpv 457
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 664 -------DQLEQKFRTEQDKANFLSQQL-----------EEIKHQIAKNKAIEKGEVVSQEAELRhrfrleeaKSRDLKA 725
Cdd:PRK01156 458 cgttlgeEKSNHIINHYNEKKSRLEEKIreieievkdidEKIVDLKKRKEYLESEEINKSINEYN--------KIESARA 529
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 726 EVQALKEKIHELMNKEDQLSQLQVDYSVLQQRFMEEENKNKNMGQEVLNLTKELELSKRY---SRALRPSVNGRRMVDVP 802
Cdd:PRK01156 530 DLEDIKIKINELKDKHDKYEEIKNRYKSLKLEDLDSKRTSWLNALAVISLIDIETNRSRSneiKKQLNDLESRLQEIEIG 609
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 585420407 803 VTSTGVQTDAVSGEaAEEETPAVFIRKSFQEENHIMSNLRQVGLKKPVERSSVLDRYPPAANELTMRKSWI 873
Cdd:PRK01156 610 FPDDKSYIDKSIRE-IENEANNLNNKYNEIQENKILIEKLRGKIDNYKKQIAEIDSIIPDLKEITSRINDI 679
|
|
| HAP1_N |
pfam04849 |
HAP1 N-terminal conserved region; This family represents an N-terminal conserved region found ... |
229-368 |
2.87e-03 |
|
HAP1 N-terminal conserved region; This family represents an N-terminal conserved region found in several huntingtin-associated protein 1 (HAP1) homologs. HAP1 binds to huntingtin in a polyglutamine repeat-length-dependent manner. However, its possible role in the pathogenesis of Huntington's disease is unclear. This family also includes a similar N-terminal conserved region from hypothetical protein products of ALS2CR3 genes found in the human juvenile amyotrophic lateral sclerosis critical region 2q33-2q34.
Pssm-ID: 461455 [Multi-domain] Cd Length: 309 Bit Score: 41.16 E-value: 2.87e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 229 EKENakrlNKLRDELVKLKSFALMLVDERQMHI----EQLGLQSQKVQDLTQKL-REEEEklkaiTSKSKEDRQKLLKLE 303
Cdd:pfam04849 177 EEEN----LKLRSEASHLKTETDTYEEKEQQLMsdcvEQLSEANQQMAELSEELaRKMEE-----NLRQQEEITSLLAQI 247
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 585420407 304 VDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLTQRIEELEETnknLQKAEEELQELRDK 368
Cdd:pfam04849 248 VDLQHKCKELGIENEELQQHLQASKEAQRQLTSELQELQDRYAECLGM---LHEAQEELKELRKK 309
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
358-563 |
2.96e-03 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 41.35 E-value: 2.96e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 358 AEEELQELRDKIakgecgnSSLMAEVENLRKRVLEMegkDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSE 437
Cdd:COG3883 14 ADPQIQAKQKEL-------SELQAELEAAQAELDAL---QAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEE 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 438 L-EKLEE-AFSKSKSECTQLHLNLEKEKNLTKDLLNELEVV-------KSRVKELECSESRLEKAELSLKDDLTKLKSFT 508
Cdd:COG3883 84 RrEELGErARALYRSGGSVSYLDVLLGSESFSDFLDRLSALskiadadADLLEELKADKAELEAKKAELEAKLAELEALK 163
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 585420407 509 VMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSE 563
Cdd:COG3883 164 AELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAA 218
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
356-530 |
3.26e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 40.68 E-value: 3.26e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 356 QKAEEELQELRDKIAKgecgnssLMAEVENLRKRVLEMEgkdEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRM 435
Cdd:COG1579 6 LRALLDLQELDSELDR-------LEHRLKELPAELAELE---DELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARI 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 436 SELEKLEEAFSKSK------SECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELecsESRLEKAELSLKDDLTKLKSFTV 509
Cdd:COG1579 76 KKYEEQLGNVRNNKeyealqKEIESLKRRISDLEDEILELMERIEELEEELAEL---EAELAELEAELEEKKAELDEELA 152
|
170 180
....*....|....*....|.
gi 585420407 510 MLVDERKNMMEKIKQEERKVD 530
Cdd:COG1579 153 ELEAELEELEAEREELAAKIP 173
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
209-687 |
3.28e-03 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 41.73 E-value: 3.28e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 209 QERERLKKLLEQEKAYQARKEKENAK------RLNKLRDELVKLKSFALMLVDERQMHIEQL-------GLQSQKVQDLT 275
Cdd:pfam10174 216 HRRNQLQPDPAKTKALQTVIEMKDTKisslerNIRDLEDEVQMLKTNGLLHTEDREEEIKQMevykshsKFMKNKIDQLK 295
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 276 QKLREEEEKLKAITSK-----------------------SKEDRQKLLKLEVD-----------FEHKASRFSQEHEEMN 321
Cdd:pfam10174 296 QELSKKESELLALQTKletltnqnsdckqhievlkesltAKEQRAAILQTEVDalrlrleekesFLNKKTKQLQDLTEEK 375
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 322 AKLANQESHNRQL----RLKLVGLTQRIEELEEtnkNLQKAEEELQELRDKIAKGECGNSSLMAEVENLRKRVLEMEGKD 397
Cdd:pfam10174 376 STLAGEIRDLKDMldvkERKINVLQKKIENLQE---QLRDKDKQLAGLKERVKSLQTDSSNTDTALTTLEEALSEKERII 452
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 398 EEItkTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLEKEKNLTKDLLNELEVVK 477
Cdd:pfam10174 453 ERL--KEQREREDRERLEELESLKKENKDLKEKVSALQPELTEKESSLIDLKEHASSLASSGLKKDSKLKSLEIAVEQKK 530
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 478 SRVKELEcsesrlekaelslkddlTKLKSFTVMLVDERKN--MMEKIKQEERKVdglnKNFKVEQGKVMDVTEKLIEESK 555
Cdd:pfam10174 531 EECSKLE-----------------NQLKKAHNAEEAVRTNpeINDRIRLLEQEV----ARYKEESGKAQAEVERLLGILR 589
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 556 KLLKLKSEMEEKVYNLTRERDELIGKLKSEEEKSSELSCsvdllKKRLDGIEEVEreitRGRSRKGSELTCPEDNKIKEL 635
Cdd:pfam10174 590 EVENEKNDKDKKIAELESLTLRQMKEQNKKVANIKHGQQ-----EMKKKGAQLLE----EARRREDNLADNSQQLQLEEL 660
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*
gi 585420407 636 TLEIERLKkrlQQLEVVEGDLMKTED---EYDQLEQKFRTEQDKanflsqQLEEI 687
Cdd:pfam10174 661 MGALEKTR---QELDATKARLSSTQQslaEKDGHLTNLRAERRK------QLEEI 706
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
297-576 |
3.78e-03 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 41.42 E-value: 3.78e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 297 QKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLTQRIEELEETNKNLQKAEEELQELRDKIAKGECGN 376
Cdd:pfam07888 48 QAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSASSEELSEEKDALLAQRAAH 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 377 SSLMAEVEN----LRKRVLEMEGKDEEITKTESQCRELRKklqEEEHHSKELRLeveKLQKRMSELEKLEEAFSKSKSEC 452
Cdd:pfam07888 128 EARIRELEEdiktLTQRVLERETELERMKERAKKAGAQRK---EEEAERKQLQA---KLQQTEEELRSLSKEFQELRNSL 201
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 453 TQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRL----EKAELS------LKDDLTKLKS---------------- 506
Cdd:pfam07888 202 AQRDTQVLQLQDTITTLTQKLTTAHRKEAENEALLEELrslqERLNASerkvegLGEELSSMAAqrdrtqaelhqarlqa 281
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 585420407 507 --FTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYNLTRERD 576
Cdd:pfam07888 282 aqLTLQLADASLALREGRARWAQERETLQQSAEADKDRIEKLSAELQRLEERLQEERMEREKLEVELGREKD 353
|
|
| Filament |
pfam00038 |
Intermediate filament protein; |
144-364 |
4.00e-03 |
|
Intermediate filament protein;
Pssm-ID: 459643 [Multi-domain] Cd Length: 313 Bit Score: 40.67 E-value: 4.00e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 144 EDVYEKPISELDRLEEKQKETYRRMLEQLLLAEKCHRRTVYELENEKHKHTDYMNKSDDFTNL---LEQERERLKKLLEQ 220
Cdd:pfam00038 35 SELRQKKGAEPSRLYSLYEKEIEDLRRQLDTLTVERARLQLELDNLRLAAEDFRQKYEDELNLrtsAENDLVGLRKDLDE 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 221 ekAYQARKEKENakRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQ----SQKVQDLTQKLREEEEKLKAITSKSKEDr 296
Cdd:pfam00038 115 --ATLARVDLEA--KIESLKEELAFLKKNHEEEVRELQAQVSDTQVNvemdAARKLDLTSALAEIRAQYEEIAAKNREE- 189
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 585420407 297 qkllkLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLTQRIEELEETNKNLQKAEEELQE 364
Cdd:pfam00038 190 -----AEEWYQSKLEELQQAAARNGDALRSAKEEITELRRTIQSLEIELQSLKKQKASLERQLAETEE 252
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
520-755 |
4.20e-03 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 41.15 E-value: 4.20e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 520 EKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYNLTRERDELIGKLKSEEEKSSELSCSVDLL 599
Cdd:PHA02562 195 QQIKTYNKNIEEQRKKNGENIARKQNKYDELVEEAKTIKAEIEELTDELLNLVMDIEDPSAALNKLNTAAAKIKSKIEQF 274
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 600 KKRLDGIEEvereitrgrsrKGSELTC-----PEDNKIKELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQ 674
Cdd:PHA02562 275 QKVIKMYEK-----------GGVCPTCtqqisEGPDRITKIKDKLKELQHSLEKLDTAIDELEEIMDEFNEQSKKLLELK 343
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 675 DKanfLSQQLEEIKHQIAKNKAIEKgevVSQEAELRHRFRLEEaksrdLKAEVQALKEKIHELMNKEDQLSQLQVDYSVL 754
Cdd:PHA02562 344 NK---ISTNKQSLITLVDKAKKVKA---AIEELQAEFVDNAEE-----LAKLQDELDKIVKTKSELVKEKYHRGIVTDLL 412
|
.
gi 585420407 755 Q 755
Cdd:PHA02562 413 K 413
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
269-440 |
4.51e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 40.29 E-value: 4.51e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 269 QKVQDLTQKLREEEEKLKAITSKSKEDRQKLLKLEVDFEHKASRFsqehEEMNAKLANQEShNRQLRlklvGLTQRIEEL 348
Cdd:COG1579 31 AELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARI----KKYEEQLGNVRN-NKEYE----ALQKEIESL 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 349 EetnKNLQKAEEELQElrdkiakgecgnssLMAEVENLRKRVLEMEgkdEEITKTESQCRELRKKLQEEEhhsKELRLEV 428
Cdd:COG1579 102 K---RRISDLEDEILE--------------LMERIEELEEELAELE---AELAELEAELEEKKAELDEEL---AELEAEL 158
|
170
....*....|..
gi 585420407 429 EKLQKRMSELEK 440
Cdd:COG1579 159 EELEAEREELAA 170
|
|
| PLN03229 |
PLN03229 |
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional |
275-568 |
4.69e-03 |
|
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional
Pssm-ID: 178768 [Multi-domain] Cd Length: 762 Bit Score: 41.38 E-value: 4.69e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 275 TQKLREEEEKLKAITSKSKEDRQKLLKLEVDfehkasrfsqeheEMNAKLANQESHNRQLRLKLVGLTQRIEELEEtnkN 354
Cdd:PLN03229 431 VRELEGEVEKLKEQILKAKESSSKPSELALN-------------EMIEKLKKEIDLEYTEAVIAMGLQERLENLRE---E 494
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 355 LQKAEEELQ----ELRDKIAK---------GECGN-SSLMAEVENLR---KRVLEMEGKDeeitKTESQCRELRKKLQE- 416
Cdd:PLN03229 495 FSKANSQDQlmhpVLMEKIEKlkdefnkrlSRAPNyLSLKYKLDMLNefsRAKALSEKKS----KAEKLKAEINKKFKEv 570
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 417 -EEHHSKElRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLEKE-KNLTKDLLNELEVVKSRVKELECS---ESRLE 491
Cdd:PLN03229 571 mDRPEIKE-KMEALKAEVASSGASSGDELDDDLKEKVEKMKKEIELElAGVLKSMGLEVIGVTKKNKDTAEQtppPNLQE 649
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 585420407 492 KAElSLKDDLTKlKSFTVMLVDERKNMMEKIKQEERKVdglnknfkveqGKVMDVTEKlieesKKLLKLKSEMEEKV 568
Cdd:PLN03229 650 KIE-SLNEEINK-KIERVIRSSDLKSKIELLKLEVAKA-----------SKTPDVTEK-----EKIEALEQQIKQKI 708
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
138-768 |
5.35e-03 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 41.19 E-value: 5.35e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 138 QEKSIGEDVYEKPISELDRLEEKQKETYRRMLEQLLLAEKCHRRTVYELEneKHKHTDYMNKsddftnlleqererLKKL 217
Cdd:TIGR01612 693 EDKAKLDDLKSKIDKEYDKIQNMETATVELHLSNIENKKNELLDIIVEIK--KHIHGEINKD--------------LNKI 756
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 218 LEQEKAyqarKEKENAKRLN---KLRDELVKLKSfalMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAITSKske 294
Cdd:TIGR01612 757 LEDFKN----KEKELSNKINdyaKEKDELNKYKS---KISEIKNHYNDQINIDNIKDEDAKQNYDKSKEYIKTISIK--- 826
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 295 drqkllklevdfEHKASRFSQEHEEMNAKLANQEShnrqlrlKLVGLTQRIEEleetnkNLQKAEEELQELRDKIAkgec 374
Cdd:TIGR01612 827 ------------EDEIFKIINEMKFMKDDFLNKVD-------KFINFENNCKE------KIDSEHEQFAELTNKIK---- 877
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 375 gnsslmAEVENLRKRVLEMEGKDeeitkTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQ 454
Cdd:TIGR01612 878 ------AEISDDKLNDYEKKFND-----SKSLINEINKSIEEEYQNINTLKKVDEYIKICENTKESIEKFHNKQNILKEI 946
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 455 LHLNLE--KEKNLT-KDLLNELEvvksrvKELECSESRLEKA--ELSLKDDLTKLKSFTVMLVDERKNMMEKikqeerKV 529
Cdd:TIGR01612 947 LNKNIDtiKESNLIeKSYKDKFD------NTLIDKINELDKAfkDASLNDYEAKNNELIKYFNDLKANLGKN------KE 1014
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 530 DGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYNLTRERDELIGKlkseeeksselscSVDLLKKRLdgIEEV 609
Cdd:TIGR01612 1015 NMLYHQFDEKEKATNDIEQKIEDANKNIPNIEIAIHTSIYNIIDEIEKEIGK-------------NIELLNKEI--LEEA 1079
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 610 EREITRGrsrkgseltcpedNKIKeltleiERLKKRLQQLEVVEGDLmKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKH 689
Cdd:TIGR01612 1080 EINITNF-------------NEIK------EKLKHYNFDDFGKEENI-KYADEINKIKDDIKNLDQKIDHHIKALEEIKK 1139
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 690 Q----IAKNKA-IEKGEVVSQEAELRHRFRLEEAKSRDLKAEVQAlKEKIHELMNK-EDQLSQLQVDYSVLqqrfmeEEN 763
Cdd:TIGR01612 1140 KsenyIDEIKAqINDLEDVADKAISNDDPEEIEKKIENIVTKIDK-KKNIYDEIKKlLNEIAEIEKDKTSL------EEV 1212
|
....*
gi 585420407 764 KNKNM 768
Cdd:TIGR01612 1213 KGINL 1217
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
416-685 |
5.51e-03 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 41.07 E-value: 5.51e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 416 EEEHHSKELRLEVEKLQKRMSELEKLEEAFSK-SKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRL--EK 492
Cdd:PRK05771 37 KEELSNERLRKLRSLLTKLSEALDKLRSYLPKlNPLREEKKKVSVKSLEELIKDVEEELEKIEKEIKELEEEISELenEI 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 493 AEL-SLKDDLTKLKSFTVMLVDERKNmmEKIKqeeRKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKL-----KSEMEE 566
Cdd:PRK05771 117 KELeQEIERLEPWGNFDLDLSLLLGF--KYVS---VFVGTVPEDKLEELKLESDVENVEYISTDKGYVYvvvvvLKELSD 191
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 567 KVYNLTRErdeligklkseeeksselscsVDLLKKRLDGIEEVEREITRGRSRKGSEltcpeDNKIKELTLEIERLKKRL 646
Cdd:PRK05771 192 EVEEELKK---------------------LGFERLELEEEGTPSELIREIKEELEEI-----EKERESLLEELKELAKKY 245
|
250 260 270
....*....|....*....|....*....|....*....
gi 585420407 647 QQLEVVegdlmktedEYDQLEQkfrtEQDKANFLSQQLE 685
Cdd:PRK05771 246 LEELLA---------LYEYLEI----ELERAEALSKFLK 271
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
341-567 |
5.53e-03 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 40.88 E-value: 5.53e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 341 LTQRIEELE---ETNKNLQKAEEELQELRDKIAKGECGNSSLMAEVENLRKRVLEMEGK-------DEEITKTESQCREL 410
Cdd:pfam17380 301 LRQEKEEKArevERRRKLEEAEKARQAEMDRQAAIYAEQERMAMERERELERIRQEERKrelerirQEEIAMEISRMREL 380
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 411 RKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLEKEKNLTKDLLNElevvkSRVKELEcsesRL 490
Cdd:pfam17380 381 ERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLEE-----ERAREME----RV 451
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 585420407 491 EKAELSLKDDLTKLKSftvMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEK 567
Cdd:pfam17380 452 RLEEQERQQQVERLRQ---QEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQAMIEEERKRKLLEKEMEER 525
|
|
| PRK09039 |
PRK09039 |
peptidoglycan -binding protein; |
341-484 |
5.69e-03 |
|
peptidoglycan -binding protein;
Pssm-ID: 181619 [Multi-domain] Cd Length: 343 Bit Score: 40.33 E-value: 5.69e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 341 LTQRIEELEETNKnlqkaeeELQELRDKIAKGECGNSSLMAEVENLRKRVLEME-----------GKDEEITKTESQCRE 409
Cdd:PRK09039 48 ISGKDSALDRLNS-------QIAELADLLSLERQGNQDLQDSVANLRASLSAAEaersrlqallaELAGAGAAAEGRAGE 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 410 LRKKLQEEEHHSKELRLEVEKLQKRMSELEK----LEEAFSKSKSEctqlhlnlEKEKNLT-KDLLNELEV-VKSRVKEL 483
Cdd:PRK09039 121 LAQELDSEKQVSARALAQVELLNQQIAALRRqlaaLEAALDASEKR--------DRESQAKiADLGRRLNVaLAQRVQEL 192
|
.
gi 585420407 484 E 484
Cdd:PRK09039 193 N 193
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
176-555 |
5.72e-03 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 41.19 E-value: 5.72e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 176 EKCHRRTVYELENEKHKHTDYMN-------KSDDFTNLLEQERERLKKLLEQEKAYQARKEKENAKRLNK-----LRDEL 243
Cdd:TIGR01612 1460 EMADNKSQHILKIKKDNATNDHDfninelkEHIDKSKGCKDEADKNAKAIEKNKELFEQYKKDVTELLNKysalaIKNKF 1539
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 244 VKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAITSKSKEDRQKLLKLEV---DFEHKASRFSQEHEEM 320
Cdd:TIGR01612 1540 AKTKKDSEIIIKEIKDAHKKFILEAEKSEQKIKEIKKEKFRIEDDAAKNDKSNKAAIDIQLsleNFENKFLKISDIKKKI 1619
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 321 NAKLANQESHNRQL----------RLKLVG-----LTQRIEELEETNKNLQKAEEELQELRDKIAKgecgnsslmaeVEN 385
Cdd:TIGR01612 1620 NDCLKETESIEKKIssfsidsqdtELKENGdnlnsLQEFLESLKDQKKNIEDKKKELDELDSEIEK-----------IEI 1688
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 386 lrkrVLEMEGKDEEITKTEsQCRELRKKLQEEEHHSKELrleVEklqkrmSELEKLEEAFSKSKSECTQLHLNLEKEKNL 465
Cdd:TIGR01612 1689 ----DVDQHKKNYEIGIIE-KIKEIAIANKEEIESIKEL---IE------PTIENLISSFNTNDLEGIDPNEKLEEYNTE 1754
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 466 TKDLLNEL------------EVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLN 533
Cdd:TIGR01612 1755 IGDIYEEFielyniiagcleTVSKEPITYDEIKNTRINAQNEFLKIIEIEKKSKSYLDDIEAKEFDRIINHFKKKLDHVN 1834
|
410 420
....*....|....*....|....*
gi 585420407 534 KNFKVEQGKV---MDVTEKLIEESK 555
Cdd:TIGR01612 1835 DKFTKEYSKInegFDDISKSIENVK 1859
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
377-780 |
5.76e-03 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 40.86 E-value: 5.76e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 377 SSLMAEVENLRKRVLEMEGkdeEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKrmseleKLEEAFSKSKsectqlh 456
Cdd:pfam05483 81 SKLYKEAEKIKKWKVSIEA---ELKQKENKLQENRKIIEAQRKAIQELQFENEKVSL------KLEEEIQENK------- 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 457 lNLEKEKNLTKDLLNELEVV------KSRVKELECSESRLEKAEL--SLKDDLTKLKSFTVMLVDERKNMMEKIKQEERK 528
Cdd:pfam05483 145 -DLIKENNATRHLCNLLKETcarsaeKTKKYEYEREETRQVYMDLnnNIEKMILAFEELRVQAENARLEMHFKLKEDHEK 223
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 529 VDGLNKNFKVEQGK--------VMDVTEK---------LIEESK-------KLLKLKSE----MEEKVYNLTRERDELIG 580
Cdd:pfam05483 224 IQHLEEEYKKEINDkekqvsllLIQITEKenkmkdltfLLEESRdkanqleEKTKLQDEnlkeLIEKKDHLTKELEDIKM 303
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 581 KLKSEEEKSSELSCSVDLLKKRLDGIEEvEREITRGRSRKG--------SELTCPEDNKIKELTLEIERLKKRLQQLEVV 652
Cdd:pfam05483 304 SLQRSMSTQKALEEDLQIATKTICQLTE-EKEAQMEELNKAkaahsfvvTEFEATTCSLEELLRTEQQRLEKNEDQLKII 382
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 653 EGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQIAKNKAIEK--GEVVSQEAELRHRFRLEEAKSRDLKAEVQAL 730
Cdd:pfam05483 383 TMELQKKSSELEEMTKFKNNKEVELEELKKILAEDEKLLDEKKQFEKiaEELKGKEQELIFLLQAREKEIHDLEIQLTAI 462
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....
gi 585420407 731 KEK----IHELMNKEDQLSQLQVDYSVLQQRFMEEENKNKNMGQEVLNLTKELE 780
Cdd:pfam05483 463 KTSeehyLKEVEDLKTELEKEKLKNIELTAHCDKLLLENKELTQEASDMTLELK 516
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
537-751 |
6.21e-03 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 40.68 E-value: 6.21e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 537 KVEQGKVMDVTEKLIEESKKLLKLKSEMEEkvynltrerdeliGKLKSEEEKSSELSCSVDLLKKRLDGIEEVEREItrg 616
Cdd:PRK05771 39 ELSNERLRKLRSLLTKLSEALDKLRSYLPK-------------LNPLREEKKKVSVKSLEELIKDVEEELEKIEKEI--- 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 617 rsrkgSELTcpedNKIKELTLEIERLKKRLQQLEVVEG-DL-MKTEDEYDQLEQKF-RTEQDKANFLSQQLEEIKHQIAK 693
Cdd:PRK05771 103 -----KELE----EEISELENEIKELEQEIERLEPWGNfDLdLSLLLGFKYVSVFVgTVPEDKLEELKLESDVENVEYIS 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 694 NK--------AIEKGEVVSQEAELR-HRFR-------------LEEAKSR--DLKAEVQALKEKIHELMNKEDQLSQLQV 749
Cdd:PRK05771 174 TDkgyvyvvvVVLKELSDEVEEELKkLGFErleleeegtpselIREIKEEleEIEKERESLLEELKELAKKYLEELLALY 253
|
..
gi 585420407 750 DY 751
Cdd:PRK05771 254 EY 255
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
210-451 |
7.77e-03 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 40.49 E-value: 7.77e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 210 ERERLKKLLEQEKAYQARKEKENAKRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKL---- 285
Cdd:pfam17380 267 ENEFLNQLLHIVQHQKAVSERQQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMamer 346
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 286 -KAITSKSKEDRQK-------------------LLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLTQ-R 344
Cdd:pfam17380 347 eRELERIRQEERKRelerirqeeiameisrmreLERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQiR 426
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 345 IEELEETNKNLQKAEE----ELQELRDKIAKGECGNSSLMAEVENLRKRVLEMEGKDEEITKTESQCR--------ELRK 412
Cdd:pfam17380 427 AEQEEARQREVRRLEEerarEMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRkilekeleERKQ 506
|
250 260 270
....*....|....*....|....*....|....*....
gi 585420407 413 KLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSE 451
Cdd:pfam17380 507 AMIEEERKRKLLEKEMEERQKAIYEEERRREAEEERRKQ 545
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
208-442 |
7.97e-03 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 40.54 E-value: 7.97e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 208 EQERERLKKLLEQEKAYQARKEKENAKRLN------KLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLREE 281
Cdd:pfam01576 738 EQGEEKRRQLVKQVRELEAELEDERKQRAQavaakkKLELDLKELEAQIDAANKGREEAVKQLKKLQAQMKDLQRELEEA 817
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 282 EEKLKAITSKSKEDRQKLLKLEVDFehkasrfSQEHEEmnakLANQESHNRQlrlklvgltqrieeleetnknlqkAEEE 361
Cdd:pfam01576 818 RASRDEILAQSKESEKKLKNLEAEL-------LQLQED----LAASERARRQ------------------------AQQE 862
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 362 LQELRDKIAKGECGNSSLMAEVENLRKRVLEMEGK-DEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEK 440
Cdd:pfam01576 863 RDELADEIASGASGKSALQDEKRRLEARIAQLEEElEEEQSNTELLNDRLRKSTLQVEQLTTELAAERSTSQKSESARQQ 942
|
..
gi 585420407 441 LE 442
Cdd:pfam01576 943 LE 944
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
384-515 |
8.77e-03 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 40.23 E-value: 8.77e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 384 ENLRKRVLEMEGKDEEITKTESQCRELRKKLQEEEHHSKELRLE-------VEKLQKRMSELEKLEEAFSKSKSECTqlh 456
Cdd:COG2433 392 EEEPEAEREKEHEERELTEEEEEIRRLEEQVERLEAEVEELEAEleekderIERLERELSEARSEERREIRKDREIS--- 468
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 585420407 457 lNLEKEknlTKDLLNELEVVKSRVKELECSESRLEKA-ELSLKDDLT---KLKSFT---VMLVDER 515
Cdd:COG2433 469 -RLDRE---IERLERELEEERERIEELKRKLERLKELwKLEHSGELVpvkVVEKFTkeaIRRLEEE 530
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
382-579 |
9.10e-03 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 40.30 E-value: 9.10e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 382 EVENLRKrvlemEGKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRmsELEKLEEAFSKSKSEctqlHLNLEK 461
Cdd:PRK05771 32 HIEDLKE-----ELSNERLRKLRSLLTKLSEALDKLRSYLPKLNPLREEKKKV--SVKSLEELIKDVEEE----LEKIEK 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 585420407 462 EknlTKDLLNELEVVKSRVKELECSESRLEK-----AELSLKDDLTKLKSFTVML----VDERKNMMEKIKQEERKVDGL 532
Cdd:PRK05771 101 E---IKELEEEISELENEIKELEQEIERLEPwgnfdLDLSLLLGFKYVSVFVGTVpedkLEELKLESDVENVEYISTDKG 177
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 585420407 533 N--------KNFKVEQGKVM---DVTEKLIEESKKLLKLKSEMEEKVYNLTRERDELI 579
Cdd:PRK05771 178 YvyvvvvvlKELSDEVEEELkklGFERLELEEEGTPSELIREIKEELEEIEKERESLL 235
|
|
| |
