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Conserved domains on  [gi|959672215|ref|NP_001304663|]
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pre-B-cell leukemia transcription factor-interacting protein 1 isoform 2 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG4913 super family cl25907
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
243-374 6.72e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


The actual alignment was detected with superfamily member COG4913:

Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 53.00  E-value: 6.72e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 959672215  243 LDKLAKENQDIRLLQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQgeafqraLESELQQLRARLQGLEADCVRGPDg 322
Cdd:COG4913   677 LERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQ-------AEEELDELQDRLEAAEDLARLELR- 748

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 959672215  323 vclsggrgPQGDKAIREQGPREQEPELS--FLKQKEQLEAEAQALRQELERQRR 374
Cdd:COG4913   749 --------ALLEERFAAALGDAVERELRenLEERIDALRARLNRAEEELERAMR 794
PRK11281 super family cl46976
mechanosensitive channel MscK;
349-420 3.21e-04

mechanosensitive channel MscK;


The actual alignment was detected with superfamily member PRK11281:

Pssm-ID: 481316 [Multi-domain]  Cd Length: 1113  Bit Score: 44.13  E-value: 3.21e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 959672215  349 LSFLKQKEQLEAEAQALRQELERQRRLLGSVQQDLER---SLQDASRGDPAHAGLAELGHRLAQKLQGLENWGQD 420
Cdd:PRK11281   69 LALLDKIDRQKEETEQLKQQLAQAPAKLRQAQAELEAlkdDNDEETRETLSTLSLRQLESRLAQTLDQLQNAQND 143
 
Name Accession Description Interval E-value
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
243-374 6.72e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 53.00  E-value: 6.72e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 959672215  243 LDKLAKENQDIRLLQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQgeafqraLESELQQLRARLQGLEADCVRGPDg 322
Cdd:COG4913   677 LERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQ-------AEEELDELQDRLEAAEDLARLELR- 748

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 959672215  323 vclsggrgPQGDKAIREQGPREQEPELS--FLKQKEQLEAEAQALRQELERQRR 374
Cdd:COG4913   749 --------ALLEERFAAALGDAVERELRenLEERIDALRARLNRAEEELERAMR 794
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 242-390 3.12e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 47.36  E-value: 3.12e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 959672215   242 LLDKLAKENQDIRLLQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEADCVRGpd 321
Cdd:TIGR02168  244 LQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEEL-- 321

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 959672215   322 gvclsggrgpQGDKAIREQGPREQEPELSFLKQK-EQLEAEAQALRQELERQRRLLgsvqQDLERSLQDA 390
Cdd:TIGR02168  322 ----------EAQLEELESKLDELAEELAELEEKlEELKEELESLEAELEELEAEL----EELESRLEEL 377
PRK09039 PRK09039
peptidoglycan -binding protein;
255-415 5.29e-05

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 46.11  E-value: 5.29e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 959672215 255 LLQAQLQAQKEELQSLMHQpkgLEEENAQLrgALQQGEAFQraLESELQQLRARLQGLEADCVRGPDgvCLSGGRGpQGD 334
Cdd:PRK09039  43 FLSREISGKDSALDRLNSQ---IAELADLL--SLERQGNQD--LQDSVANLRASLSAAEAERSRLQA--LLAELAG-AGA 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 959672215 335 KAIREQGPREQEpelsfLKQKEQLEAEAQA----LRQELERQRRLLGSVQQDLERSlqdASRGDPAHAGLAELGHR---- 406
Cdd:PRK09039 113 AAEGRAGELAQE-----LDSEKQVSARALAqvelLNQQIAALRRQLAALEAALDAS---EKRDRESQAKIADLGRRlnva 184


                 ....*....
gi 959672215 407 LAQKLQGLE 415
Cdd:PRK09039 185 LAQRVQELN 193
DUF4175 pfam13779
Domain of unknown function (DUF4175);
197-422 1.02e-04

Domain of unknown function (DUF4175);


Pssm-ID: 463981 [Multi-domain]  Cd Length: 833  Bit Score: 45.75  E-value: 1.02e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 959672215  197 EEVERQVlpdPEVLEAVGDRQDGLREQ-LQAPVPPDSVPSLQNMGLLLDKLAKENQDIRLL-----QAQLQAQKEELQSL 270
Cdd:pfam13779 509 EEIAKLM---QELREALDDYMQALAEQaQQNPQDLQQPDDPNAQEMTQQDLQRMLDRIEELarsgrRAEAQQMLSQLQQM 585

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 959672215  271 MhqpkgleeENAQL-RGALQQGEAFQRALES--ELQQLRARLQGL-------------EADCVRGPDGVCLSGGRGPQGD 334
Cdd:pfam13779 586 L--------ENLQAgQPQQQQQQGQSEMQQAmdELGDLLREQQQLldetfrqlqqqggQQQGQPGQQGQQGQGQQPGQGG 657

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 959672215  335 KAIREQGPREQEPElsflkQKEQLEAEAQALRQELERQRRLLGSVQQ--------DLERSLQDA----SRGDPAHA---- 398
Cdd:pfam13779 658 QQPGAQMPPQGGAE-----ALGDLAERQQALRRRLEELQDELKELGGkepgqalgDAGRAMRDAeealGQGDLAGAvdaq 732

                         250       260
                  ....*....|....*....|....*....
gi 959672215  399 -----GLAELGHRLAQKLQGLENWGQDPG 422
Cdd:pfam13779 733 graleALRKGAQQLAEAMQQQQGQGQQPG 761
PRK11281 PRK11281
mechanosensitive channel MscK;
349-420 3.21e-04

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 44.13  E-value: 3.21e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 959672215  349 LSFLKQKEQLEAEAQALRQELERQRRLLGSVQQDLER---SLQDASRGDPAHAGLAELGHRLAQKLQGLENWGQD 420
Cdd:PRK11281   69 LALLDKIDRQKEETEQLKQQLAQAPAKLRQAQAELEAlkdDNDEETRETLSTLSLRQLESRLAQTLDQLQNAQND 143
 
Name Accession Description Interval E-value
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
243-374 6.72e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 53.00  E-value: 6.72e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 959672215  243 LDKLAKENQDIRLLQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQgeafqraLESELQQLRARLQGLEADCVRGPDg 322
Cdd:COG4913   677 LERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQ-------AEEELDELQDRLEAAEDLARLELR- 748

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 959672215  323 vclsggrgPQGDKAIREQGPREQEPELS--FLKQKEQLEAEAQALRQELERQRR 374
Cdd:COG4913   749 --------ALLEERFAAALGDAVERELRenLEERIDALRARLNRAEEELERAMR 794
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 244-412 1.35e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 48.78  E-value: 1.35e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 959672215 244 DKLAKENQDIRLLQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEADcvrgpdgv 323
Cdd:COG1196  274 LELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEE-------- 345

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 959672215 324 clsggrgpqgdkaIREQGPREQEPELSFLKQKEQLEAEAQALRQELERQRRLLGSVQQDLERSLQDASRGDPAHAGLAEL 403
Cdd:COG1196  346 -------------LEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEAL 412


                 ....*....
gi 959672215 404 GHRLAQKLQ 412
Cdd:COG1196  413 LERLERLEE 421
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
240-392 1.74e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 48.23  E-value: 1.74e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 959672215 240 GLLLDKLAKENQDI--------RLLQAQLQAQKEELQSLmhqpKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQG 311
Cdd:COG4717   45 AMLLERLEKEADELfkpqgrkpELNLKELKELEEELKEA----EEKEEEYAELQEELEELEEELEELEAELEELREELEK 120

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 959672215 312 LEADCVRGPDGVCLSGGRGPQGDKAIR-EQGPREQEPELSFLKQKEQLEAEAQALRQELERQRRLLG-SVQQDLERSLQD 389
Cdd:COG4717  121 LEKLLQLLPLYQELEALEAELAELPERlEELEERLEELRELEEELEELEAELAELQEELEELLEQLSlATEEELQDLAEE 200


                 ...
gi 959672215 390 ASR 392
Cdd:COG4717  201 LEE 203
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
243-417 1.76e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 48.37  E-value: 1.76e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 959672215  243 LDKLAKENQDIRLLQAQLQAQKEELQSLMhqpkgLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEAdcvrgpdg 322
Cdd:COG4913   264 YAAARERLAELEYLRAALRLWFAQRRLEL-----LEAELEELRAELARLEAELERLEARLDALREELDELEA-------- 330

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 959672215  323 vclsggrgpqgdkAIREQGpreqepelsfLKQKEQLEAEAQALRQELERQRRLLgsvqQDLERSLQDASRGDPAHA-GLA 401
Cdd:COG4913   331 -------------QIRGNG----------GDRLEQLEREIERLERELEERERRR----ARLEALLAALGLPLPASAeEFA 383

                         170
                  ....*....|....*.
gi 959672215  402 ELGHRLAQKLQGLENW 417
Cdd:COG4913   384 ALRAEAAALLEALEEE 399
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 242-389 2.75e-05

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 46.07  E-value: 2.75e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 959672215 242 LLDKLAKENQDIRLLQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEADcvrgpd 321
Cdd:COG1579    8 ALLDLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQ------ 81

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 959672215 322 gvcLSGGRGP--------QGDKAIREQGPREQEpELSFLKQKEQLEAEAQALRQELERQRRLLGSVQQDLERSLQD 389
Cdd:COG1579   82 ---LGNVRNNkeyealqkEIESLKRRISDLEDE-ILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAE 153
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 242-390 3.12e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 47.36  E-value: 3.12e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 959672215   242 LLDKLAKENQDIRLLQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEADCVRGpd 321
Cdd:TIGR02168  244 LQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEEL-- 321

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 959672215   322 gvclsggrgpQGDKAIREQGPREQEPELSFLKQK-EQLEAEAQALRQELERQRRLLgsvqQDLERSLQDA 390
Cdd:TIGR02168  322 ----------EAQLEELESKLDELAEELAELEEKlEELKEELESLEAELEELEAEL----EELESRLEEL 377
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 245-416 3.80e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 47.36  E-value: 3.80e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 959672215   245 KLAKENQDIRLLQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEADCVRGPDGVC 324
Cdd:TIGR02168  678 EIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELT 757

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 959672215   325 LSGGRGPQGDKAIREQGPREQEPElsflKQKEQLEAEAQALRQELERQRRLLGSVQQDLERslqdasrgdpahagLAELG 404
Cdd:TIGR02168  758 ELEAEIEELEERLEEAEEELAEAE----AEIEELEAQIEQLKEELKALREALDELRAELTL--------------LNEEA 819

                          170
                   ....*....|..
gi 959672215   405 HRLAQKLQGLEN 416
Cdd:TIGR02168  820 ANLRERLESLER 831
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 241-415 4.45e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 46.85  E-value: 4.45e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 959672215 241 LLLDKLAKENQDIRLLQAQLQAQKEELQSlmhqpkgLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEAdcvrgp 320
Cdd:COG1196  229 LLLLKLRELEAELEELEAELEELEAELEE-------LEAELAELEAELEELRLELEELELELEEAQAEEYELLA------ 295

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 959672215 321 dgvclsggrgpqgdKAIREQGPREQEpelsfLKQKEQLEAEAQALRQELERQRRLLGSVQQDLERSLQDASRGDPAHAGL 400
Cdd:COG1196  296 --------------ELARLEQDIARL-----EERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEA 356

                        170
                 ....*....|....*
gi 959672215 401 AELGHRLAQKLQGLE 415
Cdd:COG1196  357 EAELAEAEEALLEAE 371
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
244-404 4.53e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 46.83  E-value: 4.53e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 959672215  244 DKLAKENQDIRLLQAQLQAQKEELQSLmhqpKGLEEENAQLRGALQQGEAFQ------RALESELQQLRARLQGLEADcv 317
Cdd:COG4913   610 AKLAALEAELAELEEELAEAEERLEAL----EAELDALQERREALQRLAEYSwdeidvASAEREIAELEAELERLDAS-- 683

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 959672215  318 rgpdgvclsggrgpqgdkaireqgpreqEPELSFLK-QKEQLEAEAQALRQELERQRRLLGSVQQDLERSLQDASRGDPA 396
Cdd:COG4913   684 ----------------------------SDDLAALEeQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDR 735


                  ....*...
gi 959672215  397 HAGLAELG 404
Cdd:COG4913   736 LEAAEDLA 743
PRK09039 PRK09039
peptidoglycan -binding protein;
255-415 5.29e-05

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 46.11  E-value: 5.29e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 959672215 255 LLQAQLQAQKEELQSLMHQpkgLEEENAQLrgALQQGEAFQraLESELQQLRARLQGLEADCVRGPDgvCLSGGRGpQGD 334
Cdd:PRK09039  43 FLSREISGKDSALDRLNSQ---IAELADLL--SLERQGNQD--LQDSVANLRASLSAAEAERSRLQA--LLAELAG-AGA 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 959672215 335 KAIREQGPREQEpelsfLKQKEQLEAEAQA----LRQELERQRRLLGSVQQDLERSlqdASRGDPAHAGLAELGHR---- 406
Cdd:PRK09039 113 AAEGRAGELAQE-----LDSEKQVSARALAqvelLNQQIAALRRQLAALEAALDAS---EKRDRESQAKIADLGRRlnva 184


                 ....*....
gi 959672215 407 LAQKLQGLE 415
Cdd:PRK09039 185 LAQRVQELN 193
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 245-415 6.15e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 46.47  E-value: 6.15e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 959672215 245 KLAKENQDIRLLQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEADcvrgpdgvc 324
Cdd:COG1196  303 DIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAE--------- 373

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 959672215 325 LSGGRGPQGDKAIREQgpREQEPELSFLKQKEQLEAEAQALRQELERQRRLLGSVQQDLERSLQDASRGDPAHAGLAELG 404
Cdd:COG1196  374 LAEAEEELEELAEELL--EALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEE 451

                        170
                 ....*....|.
gi 959672215 405 HRLAQKLQGLE 415
Cdd:COG1196  452 AELEEEEEALL 462
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 244-431 7.38e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 46.20  E-value: 7.38e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 959672215   244 DKLAKENQDIRLLQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEAdcvrgpdgv 323
Cdd:TIGR02168  344 EKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLED--------- 414

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 959672215   324 clsggRGPQGDKAIREQGPREQEPELSFLKQK-EQLEAEAQALRQELERQRRLLGSVQQDLERSLQdasRGDPAHAGLAE 402
Cdd:TIGR02168  415 -----RRERLQQEIEELLKKLEEAELKELQAElEELEEELEELQEELERLEEALEELREELEEAEQ---ALDAAERELAQ 486

                          170       180
                   ....*....|....*....|....*....
gi 959672215   403 LGHRLAQkLQGLENWGQDPGVSANASKAW 431
Cdd:TIGR02168  487 LQARLDS-LERLQENLEGFSEGVKALLKN 514
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 257-416 8.18e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 46.20  E-value: 8.18e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 959672215   257 QAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEadcvRGPDGVCLSGGRGPQGDKA 336
Cdd:TIGR02168  669 NSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELS----RQISALRKDLARLEAEVEQ 744

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 959672215   337 IREQGPREQEPELSFLKQKEQLEAEAQALRQELERQRRLLGSVQQDLERSLQDA----SRGDPAHAGLAELGHRLAQKLQ 412
Cdd:TIGR02168  745 LEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELkalrEALDELRAELTLLNEEAANLRE 824


                   ....
gi 959672215   413 GLEN 416
Cdd:TIGR02168  825 RLES 828
DUF4175 pfam13779
Domain of unknown function (DUF4175);
197-422 1.02e-04

Domain of unknown function (DUF4175);


Pssm-ID: 463981 [Multi-domain]  Cd Length: 833  Bit Score: 45.75  E-value: 1.02e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 959672215  197 EEVERQVlpdPEVLEAVGDRQDGLREQ-LQAPVPPDSVPSLQNMGLLLDKLAKENQDIRLL-----QAQLQAQKEELQSL 270
Cdd:pfam13779 509 EEIAKLM---QELREALDDYMQALAEQaQQNPQDLQQPDDPNAQEMTQQDLQRMLDRIEELarsgrRAEAQQMLSQLQQM 585

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 959672215  271 MhqpkgleeENAQL-RGALQQGEAFQRALES--ELQQLRARLQGL-------------EADCVRGPDGVCLSGGRGPQGD 334
Cdd:pfam13779 586 L--------ENLQAgQPQQQQQQGQSEMQQAmdELGDLLREQQQLldetfrqlqqqggQQQGQPGQQGQQGQGQQPGQGG 657

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 959672215  335 KAIREQGPREQEPElsflkQKEQLEAEAQALRQELERQRRLLGSVQQ--------DLERSLQDA----SRGDPAHA---- 398
Cdd:pfam13779 658 QQPGAQMPPQGGAE-----ALGDLAERQQALRRRLEELQDELKELGGkepgqalgDAGRAMRDAeealGQGDLAGAvdaq 732

                         250       260
                  ....*....|....*....|....*....
gi 959672215  399 -----GLAELGHRLAQKLQGLENWGQDPG 422
Cdd:pfam13779 733 graleALRKGAQQLAEAMQQQQGQGQQPG 761
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 242-416 1.25e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 45.43  E-value: 1.25e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 959672215   242 LLDKLAKENQDIRLLQAQLQAQKEELQSLmhqpkglEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEADCVRGPD 321
Cdd:TIGR02168  759 LEAEIEELEERLEEAEEELAEAEAEIEEL-------EAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLER 831

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 959672215   322 GVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQLEA------EAQALRQELERQRRLLGSVQQDLERSLQDASRG-D 394
Cdd:TIGR02168  832 RIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEEleseleALLNERASLEEALALLRSELEELSEELRELESKrS 911

                          170       180
                   ....*....|....*....|....*
gi 959672215   395 PAHAGLAELGHRLAQ---KLQGLEN 416
Cdd:TIGR02168  912 ELRRELEELREKLAQlelRLEGLEV 936
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 245-415 1.79e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.37  E-value: 1.79e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 959672215 245 KLAKENQDIRLLQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEADCVRGPD--- 321
Cdd:COG4942   28 ELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEela 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 959672215 322 ---GVCLSGGRGPQGDKAIREQGPREQEPELSFLKQ-KEQLEAEAQALR---QELERQRRLLGSVQQDLERSLQDASRgd 394
Cdd:COG4942  108 ellRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYlAPARREQAEELRadlAELAALRAELEAERAELEALLAELEE-- 185

                        170       180
                 ....*....|....*....|.
gi 959672215 395 pAHAGLAELGHRLAQKLQGLE 415
Cdd:COG4942  186 -ERAALEALKAERQKLLARLE 205
PRK11281 PRK11281
mechanosensitive channel MscK;
349-420 3.21e-04

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 44.13  E-value: 3.21e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 959672215  349 LSFLKQKEQLEAEAQALRQELERQRRLLGSVQQDLER---SLQDASRGDPAHAGLAELGHRLAQKLQGLENWGQD 420
Cdd:PRK11281   69 LALLDKIDRQKEETEQLKQQLAQAPAKLRQAQAELEAlkdDNDEETRETLSTLSLRQLESRLAQTLDQLQNAQND 143
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 196-385 5.36e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 43.51  E-value: 5.36e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 959672215   196 MEEVERQVLPDPEVLEAVGDRQDGLREQLQapvppdsvpslqnmgLLLDKLAKENQDIRLLQAQLQAQKEELQSLMHQPK 275
Cdd:TIGR02168  784 IEELEAQIEQLKEELKALREALDELRAELT---------------LLNEEAANLRERLESLERRIAATERRLEDLEEQIE 848

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 959672215   276 GLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEAdcvrgpdgvclsggrgpqgdkAIREQgpREQEPELSflKQK 355
Cdd:TIGR02168  849 ELSEDIESLAAEIEELEELIEELESELEALLNERASLEE---------------------ALALL--RSELEELS--EEL 903

                          170       180       190
                   ....*....|....*....|....*....|
gi 959672215   356 EQLEAEAQALRQELERQRRLLGSVQQDLER 385
Cdd:TIGR02168  904 RELESKRSELRRELEELREKLAQLELRLEG 933
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 198-402 8.15e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 43.02  E-value: 8.15e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 959672215  198 EVERQVLPDPEVLEAVGDRQDGLREQLQApvppdsvpslqnmgllLDKLAKENQDIRLLQAQL-QAQKEELQSLMHQPKG 276
Cdd:COG3096   495 QTARELLRRYRSQQALAQRLQQLRAQLAE----------------LEQRLRQQQNAERLLEEFcQRIGQQLDAAEELEEL 558

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 959672215  277 LEEENAQLRGALQQGEAFQ---RALESELQQLRARLQGLEAdcvrgpdgvclsggRGPQGDKA------IREQG--PREQ 345
Cdd:COG3096   559 LAELEAQLEELEEQAAEAVeqrSELRQQLEQLRARIKELAA--------------RAPAWLAAqdalerLREQSgeALAD 624

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 959672215  346 EPEL-SFLKQKEQLEAEAQALRQELERQRRLLgsvQQDLERSLQDASRGDPAHAGLAE 402
Cdd:COG3096   625 SQEVtAAMQQLLEREREATVERDELAARKQAL---ESQIERLSQPGGAEDPRLLALAE 679
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
242-385 8.34e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 42.83  E-value: 8.34e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 959672215 242 LLDKLAKENQDIRLLQAQLQAQKEELQSL--MHQPKGLEEENAQLRGALQQGEAFQRALES---ELQQLRARLQGLEADC 316
Cdd:COG4717   93 LQEELEELEEELEELEAELEELREELEKLekLLQLLPLYQELEALEAELAELPERLEELEErleELRELEEELEELEAEL 172

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 959672215 317 VRGPDgvclsggrgpQGDKAIREQGPREQEPELSFLKQKEQLEAEAQALRQELERQRRLLGSVQQDLER 385
Cdd:COG4717  173 AELQE----------ELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQ 231
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 252-389 1.12e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 42.36  E-value: 1.12e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 959672215   252 DIRLLQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEADcvrgpdgvcLSGGRGP 331
Cdd:TIGR02169  724 EIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEAR---------LSHSRIP 794

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 959672215   332 QGDKAIREQGPREQEPELSF------LKQKEQLEAEAQALRQELERQRRLLGSVQQDLERSLQD 389
Cdd:TIGR02169  795 EIQAELSKLEEEVSRIEARLreieqkLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIEN 858
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 216-315 1.20e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.67  E-value: 1.20e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 959672215 216 RQDGLREQLQAPVPPDSVPSLQNMGLLLDKLAKENQDIRLLQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQ 295
Cdd:COG4942  118 RQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAER 197

                         90       100
                 ....*....|....*....|....
gi 959672215 296 RA----LESELQQLRARLQGLEAD 315
Cdd:COG4942  198 QKllarLEKELAELAAELAELQQE 221
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
242-411 1.52e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.82  E-value: 1.52e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 959672215  242 LLDKLAKENQDIRLLQAQLQAQKEELQSLmhqpkgleeeNAQLRGA----LQQGEAFQRALESELQQLRARLQGLEADCv 317
Cdd:COG4913   300 LRAELARLEAELERLEARLDALREELDEL----------EAQIRGNggdrLEQLEREIERLERELEERERRRARLEALL- 368

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 959672215  318 rgpDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQLEAEAQALRQELERQRRLLGSVQQDLERslqdasRGDPAH 397
Cdd:COG4913   369 ---AALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLER------RKSNIP 439

                         170
                  ....*....|....
gi 959672215  398 AGLAELGHRLAQKL 411
Cdd:COG4913   440 ARLLALRDALAEAL 453
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 244-314 1.74e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.29  E-value: 1.74e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 959672215 244 DKLAKENQDIRLLQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEA 314
Cdd:COG4942   20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEK 90
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 240-416 2.94e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 41.20  E-value: 2.94e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 959672215   240 GLLLDKLAKENQDIRLLQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEADcvrg 319
Cdd:TIGR02168  228 ALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQ---- 303

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 959672215   320 pdgvclsggrgpqgdkaIREQGPREQEPElsflKQKEQLEAEAQALRQELERQRRLLGSVQQDLERSLQDasrgdpaHAG 399
Cdd:TIGR02168  304 -----------------KQILRERLANLE----RQLEELEAQLEELESKLDELAEELAELEEKLEELKEE-------LES 355

                          170
                   ....*....|....*..
gi 959672215   400 LAELGHRLAQKLQGLEN 416
Cdd:TIGR02168  356 LEAELEELEAELEELES 372
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 237-414 3.31e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 40.52  E-value: 3.31e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 959672215 237 QNMGLLLDKLAKENQDIRLLQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEADC 316
Cdd:COG4942   34 QEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELLRAL 113

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 959672215 317 VR----GPDGVCLSGGRGPQGDK----------AIREQ--GPREQEPELSFLKQK-EQLEAEAQALRQELERQRRLLGSV 379
Cdd:COG4942  114 YRlgrqPPLALLLSPEDFLDAVRrlqylkylapARREQaeELRADLAELAALRAElEAERAELEALLAELEEERAALEAL 193

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 959672215 380 QQDLERSLQDASRGDPAHAGLAELGHRLAQKLQGL 414
Cdd:COG4942  194 KAERQKLLARLEKELAELAAELAELQQEAEELEAL 228
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
196-315 4.89e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 39.89  E-value: 4.89e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 959672215 196 MEEVERQVLPDPEVLEAVGDRQDGLREQLQApvppdsvpSLQNMGLLLDKLAKENQDIRLLQAQLQAQKEELQSLMHQPK 275
Cdd:COG4372   61 LEQLEEELEQARSELEQLEEELEELNEQLQA--------AQAELAQAQEELESLQEEAEELQEELEELQKERQDLEQQRK 132

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 959672215 276 GLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEAD 315
Cdd:COG4372  133 QLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQE 172
PspA COG1842
Phage shock protein A [Transcription, Signal transduction mechanisms];
244-403 5.02e-03

Phage shock protein A [Transcription, Signal transduction mechanisms];


Pssm-ID: 441447 [Multi-domain]  Cd Length: 217  Bit Score: 39.04  E-value: 5.02e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 959672215 244 DKLAKEN-QDIRLLQAQLQAQKEELQSLmhqpkglEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEAdcvrgpdg 322
Cdd:COG1842   83 EDLAREAlERKAELEAQAEALEAQLAQL-------EEQVEKLKEALRQLESKLEELKAKKDTLKARAKAAKA-------- 147

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 959672215 323 vclsggrgpqgDKAIREQ--GPREQEPELSF--LKQK-EQLEAEAQALRqELERQRrllgsvqqDLERSLQDASRGDPAH 397
Cdd:COG1842  148 -----------QEKVNEAlsGIDSDDATSALerMEEKiEEMEARAEAAA-ELAAGD--------SLDDELAELEADSEVE 207


                 ....*.
gi 959672215 398 AGLAEL 403
Cdd:COG1842  208 DELAAL 213
MscS_porin pfam12795
Mechanosensitive ion channel porin domain; The small mechanosensitive channel, MscS, is a part ...
 220-389 7.26e-03

Mechanosensitive ion channel porin domain; The small mechanosensitive channel, MscS, is a part of the turgor-driven solute efflux system that protects bacteria from lysis in the event of osmotic shock. The MscS protein alone is sufficient to form a functional mechanosensitive channel gated directly by tension in the lipid bilayer. The MscS proteins are heptamers of three transmembrane subunits with seven converging M3 domains, and this MscS_porin is towards the N-terminal of the molecules. The high concentration of negative charges at the extracellular entrance of the pore helps select the cations for efflux.


Pssm-ID: 432790 [Multi-domain]  Cd Length: 238  Bit Score: 38.82  E-value: 7.26e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 959672215  220 LREQLQAPVPPDSVPSLQnmgllldklAKENQDIRLLQAQLQAQKEELQSLMHQpkgLEEENAQLRGALQQGEAFQRALE 299
Cdd:pfam12795  56 LRQELAALQAKAEAAPKE---------ILASLSLEELEQRLLQTSAQLQELQNQ---LAQLNSQLIELQTRPERAQQQLS 123

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 959672215  300 S---ELQQLRARLQGleadcvrgpdgvclsggrGPQGDKAIREQGPREQEPELSFLKQK-EQLEAEAQA--LRQELERQR 373
Cdd:pfam12795 124 EarqRLQQIRNRLNG------------------PAPPGEPLSEAQRWALQAELAALKAQiDMLEQELLSnnNRQDLLKAR 185

                         170
                  ....*....|....*..
gi 959672215  374 R-LLGSVQQDLERSLQD 389
Cdd:pfam12795 186 RdLLTLRIQRLEQQLQA 202
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
200-416 9.02e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 39.37  E-value: 9.02e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 959672215 200 ERQVLPDPEVLEAVGDRQDGLREQLQAPVPPDSVPSL-QNMGLLLDKLAKENQDIRllQAQLQAQKEELQSLMHQPKGLE 278
Cdd:COG4717  306 ELQALPALEELEEEELEELLAALGLPPDLSPEELLELlDRIEELQELLREAEELEE--ELQLEELEQEIAALLAEAGVED 383

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 959672215 279 EEnaQLRGALQQGEAFQrALESELQQLRARLQGLeadcvrgpdgvclsggrgpqgDKAIREQGPREQEPELSflKQKEQL 358
Cdd:COG4717  384 EE--ELRAALEQAEEYQ-ELKEELEELEEQLEEL---------------------LGELEELLEALDEEELE--EELEEL 437

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 959672215 359 EAEAQALRQELERQRRLLGSVQQDLERSLQDASrgdpahagLAELGHRLAQKLQGLEN 416
Cdd:COG4717  438 EEELEELEEELEELREELAELEAELEQLEEDGE--------LAELLQELEELKAELRE 487
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
210-391 9.18e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 39.23  E-value: 9.18e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 959672215 210 LEAVGDRQDGLREQLQAPvpPDSVPSLQN---MGLLLDKLAKENQDIRLLQAQLQAQKEELQSLMHQpkgLEEENAQLRG 286
Cdd:COG3206  235 LAEAEARLAALRAQLGSG--PDALPELLQspvIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQ---IAALRAQLQQ 309

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 959672215 287 ALQQGEAfqrALESELQQLRARLQGLEAdcvrgpdgvclsggrgpqgdkaireqgpreqepelsflkQKEQLEAEAQALR 366
Cdd:COG3206  310 EAQRILA---SLEAELEALQAREASLQA---------------------------------------QLAQLEARLAELP 347

                        170       180       190
                 ....*....|....*....|....*....|.
gi 959672215 367 Q------ELERQRRLLGSVQQDLERSLQDAS 391
Cdd:COG3206  348 EleaelrRLEREVEVARELYESLLQRLEEAR 378
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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