NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|992860619|ref|NP_001307085|]
View 

neurexin-1 isoform gamma1 [Homo sapiens]

Protein Classification

Syndecan and 4.1m domain-containing protein( domain architecture ID 10379211)

Syndecan and 4.1m domain-containing protein

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
4.1m smart00294
putative band 4.1 homologues' binding motif;
87-105 3.24e-06

putative band 4.1 homologues' binding motif;


:

Pssm-ID: 128590  Cd Length: 19  Bit Score: 41.36  E-value: 3.24e-06
                           10
                   ....*....|....*....
gi 992860619    87 MYKYRNRDEGSYHVDESRN 105
Cdd:smart00294   1 MYRYKHRDEGSYHTHEPKG 19
Syndecan super family cl20212
Syndecan domain; Syndecans are transmembrane heparin sulfate proteoglycans which are ...
 67-102 1.14e-03

Syndecan domain; Syndecans are transmembrane heparin sulfate proteoglycans which are implicated in the binding of extracellular matrix components and growth factors.


The actual alignment was detected with superfamily member pfam01034:

Pssm-ID: 460035  Cd Length: 63  Bit Score: 35.45  E-value: 1.14e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 992860619   67 GMVVGIVAAAALCILILLYAMYKYRNRDEGSYHVDE 102
Cdd:pfam01034  11 AVIGGGVVGLLFAVLLVMFLVYRMKKKDEGSYALDE 46
 
Name Accession Description Interval E-value
4.1m smart00294
putative band 4.1 homologues' binding motif;
87-105 3.24e-06

putative band 4.1 homologues' binding motif;


Pssm-ID: 128590  Cd Length: 19  Bit Score: 41.36  E-value: 3.24e-06
                           10
                   ....*....|....*....
gi 992860619    87 MYKYRNRDEGSYHVDESRN 105
Cdd:smart00294   1 MYRYKHRDEGSYHTHEPKG 19
Syndecan pfam01034
Syndecan domain; Syndecans are transmembrane heparin sulfate proteoglycans which are ...
 67-102 1.14e-03

Syndecan domain; Syndecans are transmembrane heparin sulfate proteoglycans which are implicated in the binding of extracellular matrix components and growth factors.


Pssm-ID: 460035  Cd Length: 63  Bit Score: 35.45  E-value: 1.14e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 992860619   67 GMVVGIVAAAALCILILLYAMYKYRNRDEGSYHVDE 102
Cdd:pfam01034  11 AVIGGGVVGLLFAVLLVMFLVYRMKKKDEGSYALDE 46
 
Name Accession Description Interval E-value
4.1m smart00294
putative band 4.1 homologues' binding motif;
87-105 3.24e-06

putative band 4.1 homologues' binding motif;


Pssm-ID: 128590  Cd Length: 19  Bit Score: 41.36  E-value: 3.24e-06
                           10
                   ....*....|....*....
gi 992860619    87 MYKYRNRDEGSYHVDESRN 105
Cdd:smart00294   1 MYRYKHRDEGSYHTHEPKG 19
Syndecan pfam01034
Syndecan domain; Syndecans are transmembrane heparin sulfate proteoglycans which are ...
 67-102 1.14e-03

Syndecan domain; Syndecans are transmembrane heparin sulfate proteoglycans which are implicated in the binding of extracellular matrix components and growth factors.


Pssm-ID: 460035  Cd Length: 63  Bit Score: 35.45  E-value: 1.14e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 992860619   67 GMVVGIVAAAALCILILLYAMYKYRNRDEGSYHVDE 102
Cdd:pfam01034  11 AVIGGGVVGLLFAVLLVMFLVYRMKKKDEGSYALDE 46
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH