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Conserved domains on  [gi|1003701486|ref|NP_001307806|]
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solute carrier family 25 member 35 isoform c [Homo sapiens]

Protein Classification

solute carrier family 25 protein( domain architecture ID 10445172)

solute carrier 25 family (SLC25) protein which transfers molecules across the membranes of organelles, usually mitochondria

Gene Ontology:  GO:0016020|GO:1990542
TCDB:  2.A.29

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Mito_carr pfam00153
Mitochondrial carrier protein;
2-84 4.58e-16

Mitochondrial carrier protein;


:

Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 71.92  E-value: 4.58e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1003701486   2 DFLMSGLAACGACVFTNPLEVVKTRMQLQgelqaPGTYQRHYRNVFHAFITIGKVDGLAALQKGLAPALLYQFLMNGIRL 81
Cdd:pfam00153   8 SLLAGGIAGAIAVTVTYPLDVVKTRLQVQ-----GGSGKSKGRGILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAAAIYF 82

                  ...
gi 1003701486  82 GTY 84
Cdd:pfam00153  83 GTY 85
Mito_carr pfam00153
Mitochondrial carrier protein;
187-276 5.63e-16

Mitochondrial carrier protein;


:

Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 71.53  E-value: 5.63e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1003701486 187 LVAAMMSGIAVVLAMAPFDVACTRLYNQPTDAQGKglmYRGILDALLQTARTEGIFGMYKGIGASYFRLGPHTILSLFFW 266
Cdd:pfam00153   9 LLAGGIAGAIAVTVTYPLDVVKTRLQVQGGSGKSK---GRGILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAAAIYFGTY 85
                          90
                  ....*....|
gi 1003701486 267 DQLRSLYYTD 276
Cdd:pfam00153  86 ETLKRLLLKK 95
 
Name Accession Description Interval E-value
Mito_carr pfam00153
Mitochondrial carrier protein;
2-84 4.58e-16

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 71.92  E-value: 4.58e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1003701486   2 DFLMSGLAACGACVFTNPLEVVKTRMQLQgelqaPGTYQRHYRNVFHAFITIGKVDGLAALQKGLAPALLYQFLMNGIRL 81
Cdd:pfam00153   8 SLLAGGIAGAIAVTVTYPLDVVKTRLQVQ-----GGSGKSKGRGILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAAAIYF 82

                  ...
gi 1003701486  82 GTY 84
Cdd:pfam00153  83 GTY 85
Mito_carr pfam00153
Mitochondrial carrier protein;
187-276 5.63e-16

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 71.53  E-value: 5.63e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1003701486 187 LVAAMMSGIAVVLAMAPFDVACTRLYNQPTDAQGKglmYRGILDALLQTARTEGIFGMYKGIGASYFRLGPHTILSLFFW 266
Cdd:pfam00153   9 LLAGGIAGAIAVTVTYPLDVVKTRLQVQGGSGKSK---GRGILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAAAIYFGTY 85
                          90
                  ....*....|
gi 1003701486 267 DQLRSLYYTD 276
Cdd:pfam00153  86 ETLKRLLLKK 95
PTZ00169 PTZ00169
ADP/ATP transporter on adenylate translocase; Provisional
124-272 5.51e-08

ADP/ATP transporter on adenylate translocase; Provisional


Pssm-ID: 240302 [Multi-domain]  Cd Length: 300  Bit Score: 52.85  E-value: 5.51e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1003701486 124 YMGMFQALTEIGQKHGLVGLWRGALGGLPRVIVGSSTQLCTFSSTKDLLsqweiFPPQS-------WKLALVAAMMSGIA 196
Cdd:PTZ00169  153 FTGLFDCLMKISKQTGFLSLYQGFGVSVQGIIVYRGAYFGLYDSAKALL-----FGNDKntnilykWAVAQTVTILAGLI 227
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1003701486 197 VVlamaPFDVACTRLYNQPTDAQGKGLMYRGILDALLQTARTEGIFGMYKGIGASYFRlGPHTILSLFFWDQLRSL 272
Cdd:PTZ00169  228 SY----PFDTVRRRMMMMSGRKAKSEIQYTGTLDCWKKILKNEGLGGFFKGAWANVLR-GAGGALVLVFYDELQKL 298
PTZ00169 PTZ00169
ADP/ATP transporter on adenylate translocase; Provisional
122-251 2.96e-06

ADP/ATP transporter on adenylate translocase; Provisional


Pssm-ID: 240302 [Multi-domain]  Cd Length: 300  Bit Score: 47.46  E-value: 2.96e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1003701486 122 PIYMGMFQALTEIGQKHGLVGLWRGalgGLPRVIVGSSTQLCTFSsTKDLLSqwEIFPPQS-----WKL---ALVAAMMS 193
Cdd:PTZ00169   50 PRYSGIVNCFRRVSKEQGVLSLWRG---NTANVIRYFPTQAFNFA-FKDYFK--NMFPKYNqktdfWKFfgvNILSGGLA 123
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1003701486 194 GIAVVLAMAPFDVACTRLynqPTD-AQGKGLMYRGILDALLQTARTEGIFGMYKGIGAS 251
Cdd:PTZ00169  124 GASSLLIVYPLDFARTRL---ASDiGKGGDREFTGLFDCLMKISKQTGFLSLYQGFGVS 179
 
Name Accession Description Interval E-value
Mito_carr pfam00153
Mitochondrial carrier protein;
2-84 4.58e-16

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 71.92  E-value: 4.58e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1003701486   2 DFLMSGLAACGACVFTNPLEVVKTRMQLQgelqaPGTYQRHYRNVFHAFITIGKVDGLAALQKGLAPALLYQFLMNGIRL 81
Cdd:pfam00153   8 SLLAGGIAGAIAVTVTYPLDVVKTRLQVQ-----GGSGKSKGRGILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAAAIYF 82

                  ...
gi 1003701486  82 GTY 84
Cdd:pfam00153  83 GTY 85
Mito_carr pfam00153
Mitochondrial carrier protein;
187-276 5.63e-16

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 71.53  E-value: 5.63e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1003701486 187 LVAAMMSGIAVVLAMAPFDVACTRLYNQPTDAQGKglmYRGILDALLQTARTEGIFGMYKGIGASYFRLGPHTILSLFFW 266
Cdd:pfam00153   9 LLAGGIAGAIAVTVTYPLDVVKTRLQVQGGSGKSK---GRGILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAAAIYFGTY 85
                          90
                  ....*....|
gi 1003701486 267 DQLRSLYYTD 276
Cdd:pfam00153  86 ETLKRLLLKK 95
PTZ00169 PTZ00169
ADP/ATP transporter on adenylate translocase; Provisional
124-272 5.51e-08

ADP/ATP transporter on adenylate translocase; Provisional


Pssm-ID: 240302 [Multi-domain]  Cd Length: 300  Bit Score: 52.85  E-value: 5.51e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1003701486 124 YMGMFQALTEIGQKHGLVGLWRGALGGLPRVIVGSSTQLCTFSSTKDLLsqweiFPPQS-------WKLALVAAMMSGIA 196
Cdd:PTZ00169  153 FTGLFDCLMKISKQTGFLSLYQGFGVSVQGIIVYRGAYFGLYDSAKALL-----FGNDKntnilykWAVAQTVTILAGLI 227
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1003701486 197 VVlamaPFDVACTRLYNQPTDAQGKGLMYRGILDALLQTARTEGIFGMYKGIGASYFRlGPHTILSLFFWDQLRSL 272
Cdd:PTZ00169  228 SY----PFDTVRRRMMMMSGRKAKSEIQYTGTLDCWKKILKNEGLGGFFKGAWANVLR-GAGGALVLVFYDELQKL 298
PTZ00169 PTZ00169
ADP/ATP transporter on adenylate translocase; Provisional
122-251 2.96e-06

ADP/ATP transporter on adenylate translocase; Provisional


Pssm-ID: 240302 [Multi-domain]  Cd Length: 300  Bit Score: 47.46  E-value: 2.96e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1003701486 122 PIYMGMFQALTEIGQKHGLVGLWRGalgGLPRVIVGSSTQLCTFSsTKDLLSqwEIFPPQS-----WKL---ALVAAMMS 193
Cdd:PTZ00169   50 PRYSGIVNCFRRVSKEQGVLSLWRG---NTANVIRYFPTQAFNFA-FKDYFK--NMFPKYNqktdfWKFfgvNILSGGLA 123
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1003701486 194 GIAVVLAMAPFDVACTRLynqPTD-AQGKGLMYRGILDALLQTARTEGIFGMYKGIGAS 251
Cdd:PTZ00169  124 GASSLLIVYPLDFARTRL---ASDiGKGGDREFTGLFDCLMKISKQTGFLSLYQGFGVS 179
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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