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Conserved domains on  [gi|1031985752|ref|NP_001313611|]
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histone demethylase UTY isoform 2 [Mus musculus]

Protein Classification

KDM6 family histone demethylase( domain architecture ID 11421451)

KDM6 family histone demethylase, similar to lysine-specific demethylase 6A (KDM6A), also called UTX (ubiquitously-transcribed TPR protein on the X chromosome) that specifically demethylates 'Lys-27' of histone H3, and UTY (ubiquitously-transcribed TPR protein on the Y chromosome) that catalyzes trimethylated 'Lys-27' (H3K27me3) demethylation in histone H3

CATH:  1.25.40.10|2.60.120.10
EC:  1.14.11.-
Gene Ontology:  GO:0005515|GO:0032452|GO:0031490|GO:0046872
PubMed:  26059336|21153002|10517866|30708253|22404999|11165500|14697267|19478949
SCOP:  4001344|3001825

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
JmjC pfam02373
JmjC domain, hydroxylase; The JmjC domain belongs to the Cupin superfamily. JmjC-domain ...
 944-1052 1.10e-33

JmjC domain, hydroxylase; The JmjC domain belongs to the Cupin superfamily. JmjC-domain proteins may be protein hydroxylases that catalyze a novel histone modification. This is confirmed to be a hydroxylase: the human JmjC protein named Tyw5p unexpectedly acts in the biosynthesis of a hypermodified nucleoside, hydroxy-wybutosine, in tRNA-Phe by catalysing hydroxylation.


:

Pssm-ID: 396791  Cd Length: 114  Bit Score: 125.49  E-value: 1.10e-33
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752  944 QLCMKVPGSRIPGHQENNNFCSVNINIGPGDCEWFVVPEDYWGVLNDFCEKNN-------LNFLMSSWWPnlEDLYEANV 1016
Cdd:pfam02373    1 WLYLGMPFSTTPWHIEDQGLYSINYLHFGAPKVWYIIPPEYAEKFEKVLSDHFggeqpddLLHLNTIISP--KQLRENGI 78

                           90       100       110
                   ....*....|....*....|....*....|....*.
gi 1031985752 1017 PVYRFIQRPGDLVWINAGTVHWVQAIGWCNNITWNV 1052
Cdd:pfam02373   79 PVYRFVQKPGEFVFTFPGWYHQVFNLGFNIAEAVNF 114
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 124-374 2.50e-24

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 104.04  E-value: 2.50e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752  124 AAFLYG---LGLVYFYYNAFQWAIRAFQEVLYVDPNfcrAKEIHLRLGFMFKMNTDYESSLKHFQLAL-IDcnvctLSSV 199
Cdd:COG2956      5 VAAALGwyfKGLNYLLNGQPDKAIDLLEEALELDPE---TVEAHLALGNLYRRRGEYDRAIRIHQKLLeRD-----PDRA 76

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752  200 EIQFHIAHLYETQRKYHSAKAAYEQLLQIESLPSQVK---ATVLQQLGwmhhnmdligdnttKERYAIQYLQKSLEEDPN 276
Cdd:COG2956     77 EALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALrllAEIYEQEG--------------DWEKAIEVLERLLKLGPE 142

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752  277 SGQSWYFLGRCYSCIGKVQDAFVSYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGILY 356
Cdd:COG2956    143 NAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELY 222

                          250
                   ....*....|....*...
gi 1031985752  357 ESCNQPQDAIKCYLNAAR 374
Cdd:COG2956    223 EKLGDPEEALELLRKALE 240
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 67-155 1.07e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


:

Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 43.80  E-value: 1.07e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752   67 LNKAIHFYESLIVKAEGkvESDFFCQLGHFNLLLEDYSKALSSYQRYYSLQTDywkNAAFLYGLGLVYFYYNAFQWAIRA 146
Cdd:COG5010     70 FEESLALLEQALQLDPN--NPELYYNLALLYSRSGDKDEAKEYYEKALALSPD---NPNAYSNLAALLLSLGQDDEAKAA 144


                   ....*....
gi 1031985752  147 FQEVLYVDP 155
Cdd:COG5010    145 LQRALGTSP 153
JmjC smart00558
A domain family that is part of the cupin metalloenzyme superfamily; Probable enzymes, but of ...
 910-974 4.77e-04

A domain family that is part of the cupin metalloenzyme superfamily; Probable enzymes, but of unknown functions, that regulate chromatin reorganisation processes (Clissold and Ponting, in press).


:

Pssm-ID: 214721  Cd Length: 58  Bit Score: 39.16  E-value: 4.77e-04
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1031985752   910 QLHELTKLPafvrvvSAGNLLSHVGYTILGMNSVQLC-MKVPGSRIPGHQENNNfcSVNINIGPGD 974
Cdd:smart00558    1 QLWNLAKLP------FKLNLLSDLPEDIPGPDVGPYLyMGMAGSTTPWHIDDYD--LVNYLHQGAG 58
 
Name Accession Description Interval E-value
JmjC pfam02373
JmjC domain, hydroxylase; The JmjC domain belongs to the Cupin superfamily. JmjC-domain ...
 944-1052 1.10e-33

JmjC domain, hydroxylase; The JmjC domain belongs to the Cupin superfamily. JmjC-domain proteins may be protein hydroxylases that catalyze a novel histone modification. This is confirmed to be a hydroxylase: the human JmjC protein named Tyw5p unexpectedly acts in the biosynthesis of a hypermodified nucleoside, hydroxy-wybutosine, in tRNA-Phe by catalysing hydroxylation.


Pssm-ID: 396791  Cd Length: 114  Bit Score: 125.49  E-value: 1.10e-33
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752  944 QLCMKVPGSRIPGHQENNNFCSVNINIGPGDCEWFVVPEDYWGVLNDFCEKNN-------LNFLMSSWWPnlEDLYEANV 1016
Cdd:pfam02373    1 WLYLGMPFSTTPWHIEDQGLYSINYLHFGAPKVWYIIPPEYAEKFEKVLSDHFggeqpddLLHLNTIISP--KQLRENGI 78

                           90       100       110
                   ....*....|....*....|....*....|....*.
gi 1031985752 1017 PVYRFIQRPGDLVWINAGTVHWVQAIGWCNNITWNV 1052
Cdd:pfam02373   79 PVYRFVQKPGEFVFTFPGWYHQVFNLGFNIAEAVNF 114
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 124-374 2.50e-24

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 104.04  E-value: 2.50e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752  124 AAFLYG---LGLVYFYYNAFQWAIRAFQEVLYVDPNfcrAKEIHLRLGFMFKMNTDYESSLKHFQLAL-IDcnvctLSSV 199
Cdd:COG2956      5 VAAALGwyfKGLNYLLNGQPDKAIDLLEEALELDPE---TVEAHLALGNLYRRRGEYDRAIRIHQKLLeRD-----PDRA 76

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752  200 EIQFHIAHLYETQRKYHSAKAAYEQLLQIESLPSQVK---ATVLQQLGwmhhnmdligdnttKERYAIQYLQKSLEEDPN 276
Cdd:COG2956     77 EALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALrllAEIYEQEG--------------DWEKAIEVLERLLKLGPE 142

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752  277 SGQSWYFLGRCYSCIGKVQDAFVSYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGILY 356
Cdd:COG2956    143 NAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELY 222

                          250
                   ....*....|....*...
gi 1031985752  357 ESCNQPQDAIKCYLNAAR 374
Cdd:COG2956    223 EKLGDPEEALELLRKALE 240
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 98-369 1.08e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 49.70  E-value: 1.08e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752   98 LLLEDYSKALSSYQRYYSLQTDywkNAAFLYGLGLVYFYYNAFQWAIRAFQEVLYVDPNFCRAkeiHLRLGfMFKM---- 173
Cdd:TIGR02917  340 LRLGRVDEAIATLSPALGLDPD---DPAALSLLGEAYLALGDFEKAAEYLAKATELDPENAAA---RTQLG-ISKLsqgd 412

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752  174 ------------NTDYESSLKHFQLAL-------IDCNVCTLSSVE--------IQFHIAHLYETQRKYHSAKAAYEQLL 226
Cdd:TIGR02917  413 pseaiadletaaQLDPELGRADLLLILsylrsgqFDKALAAAKKLEkkqpdnasLHNLLGAIYLGKGDLAKAREAFEKAL 492

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752  227 QIEslPSQVKATVLQQlgwmhhNMDLIGDNTTKeryAIQYLQKSLEEDPNSGQSWYFLGRCYSCIGKVQDAFVSYRQSID 306
Cdd:TIGR02917  493 SIE--PDFFPAAANLA------RIDIQEGNPDD---AIQRFEKVLTIDPKNLRAILALAGLYLRTGNEEEAVAWLEKAAE 561

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1031985752  307 KSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGILYESCNQPQDAIKCY 369
Cdd:TIGR02917  562 LNPQEIEPALALAQYYLGKGQLKKALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSF 624
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 67-155 1.07e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 43.80  E-value: 1.07e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752   67 LNKAIHFYESLIVKAEGkvESDFFCQLGHFNLLLEDYSKALSSYQRYYSLQTDywkNAAFLYGLGLVYFYYNAFQWAIRA 146
Cdd:COG5010     70 FEESLALLEQALQLDPN--NPELYYNLALLYSRSGDKDEAKEYYEKALALSPD---NPNAYSNLAALLLSLGQDDEAKAA 144


                   ....*....
gi 1031985752  147 FQEVLYVDP 155
Cdd:COG5010    145 LQRALGTSP 153
MamA NF040959
magnetosome protein MamA; Magnetosomes are special lipid-bound organelles that comprise ...
 100-188 1.63e-04

magnetosome protein MamA; Magnetosomes are special lipid-bound organelles that comprise magnetic mineral crystals in magnetotactic bacteria (MTB). Magnetosomes are important for MTB to search for preferred microaerophilic environment. Proteins of this family typically contain five tetra-trico-peptide repeat (TPR) motifs. Based on structural analyses, MamA forms a large homooligomer through self-recognition to regulate protein-protein interaction in magnetosomes.


Pssm-ID: 468889 [Multi-domain]  Cd Length: 204  Bit Score: 44.29  E-value: 1.63e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752  100 LEDYSKALSSYQRYYSLQTDywkNAAFLYGLGLVYFYYNAFQWAIRAFQEVLYVDPNFCRakeIHLRLGFMFKMNTDYES 179
Cdd:NF040959   118 IKDYEKAVEDLEEALEEKPD---NFNLNYRLGLALDGLGQYDKAIEAFQKALELDPNEIK---YHQAIGFMYVQKGDHET 191


                   ....*....
gi 1031985752  180 SLKHFQLAL 188
Cdd:NF040959   192 AAEHFKKAM 200
TPR_1 pfam00515
Tetratricopeptide repeat;
124-157 4.60e-04

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 38.56  E-value: 4.60e-04
                           10        20        30
                   ....*....|....*....|....*....|....
gi 1031985752  124 AAFLYGLGLVYFYYNAFQWAIRAFQEVLYVDPNF 157
Cdd:pfam00515    1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
JmjC smart00558
A domain family that is part of the cupin metalloenzyme superfamily; Probable enzymes, but of ...
 910-974 4.77e-04

A domain family that is part of the cupin metalloenzyme superfamily; Probable enzymes, but of unknown functions, that regulate chromatin reorganisation processes (Clissold and Ponting, in press).


Pssm-ID: 214721  Cd Length: 58  Bit Score: 39.16  E-value: 4.77e-04
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1031985752   910 QLHELTKLPafvrvvSAGNLLSHVGYTILGMNSVQLC-MKVPGSRIPGHQENNNfcSVNINIGPGD 974
Cdd:smart00558    1 QLWNLAKLP------FKLNLLSDLPEDIPGPDVGPYLyMGMAGSTTPWHIDDYD--LVNYLHQGAG 58
 
Name Accession Description Interval E-value
JmjC pfam02373
JmjC domain, hydroxylase; The JmjC domain belongs to the Cupin superfamily. JmjC-domain ...
 944-1052 1.10e-33

JmjC domain, hydroxylase; The JmjC domain belongs to the Cupin superfamily. JmjC-domain proteins may be protein hydroxylases that catalyze a novel histone modification. This is confirmed to be a hydroxylase: the human JmjC protein named Tyw5p unexpectedly acts in the biosynthesis of a hypermodified nucleoside, hydroxy-wybutosine, in tRNA-Phe by catalysing hydroxylation.


Pssm-ID: 396791  Cd Length: 114  Bit Score: 125.49  E-value: 1.10e-33
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752  944 QLCMKVPGSRIPGHQENNNFCSVNINIGPGDCEWFVVPEDYWGVLNDFCEKNN-------LNFLMSSWWPnlEDLYEANV 1016
Cdd:pfam02373    1 WLYLGMPFSTTPWHIEDQGLYSINYLHFGAPKVWYIIPPEYAEKFEKVLSDHFggeqpddLLHLNTIISP--KQLRENGI 78

                           90       100       110
                   ....*....|....*....|....*....|....*.
gi 1031985752 1017 PVYRFIQRPGDLVWINAGTVHWVQAIGWCNNITWNV 1052
Cdd:pfam02373   79 PVYRFVQKPGEFVFTFPGWYHQVFNLGFNIAEAVNF 114
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 124-374 2.50e-24

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 104.04  E-value: 2.50e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752  124 AAFLYG---LGLVYFYYNAFQWAIRAFQEVLYVDPNfcrAKEIHLRLGFMFKMNTDYESSLKHFQLAL-IDcnvctLSSV 199
Cdd:COG2956      5 VAAALGwyfKGLNYLLNGQPDKAIDLLEEALELDPE---TVEAHLALGNLYRRRGEYDRAIRIHQKLLeRD-----PDRA 76

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752  200 EIQFHIAHLYETQRKYHSAKAAYEQLLQIESLPSQVK---ATVLQQLGwmhhnmdligdnttKERYAIQYLQKSLEEDPN 276
Cdd:COG2956     77 EALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALrllAEIYEQEG--------------DWEKAIEVLERLLKLGPE 142

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752  277 SGQSWYFLGRCYSCIGKVQDAFVSYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGILY 356
Cdd:COG2956    143 NAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELY 222

                          250
                   ....*....|....*...
gi 1031985752  357 ESCNQPQDAIKCYLNAAR 374
Cdd:COG2956    223 EKLGDPEEALELLRKALE 240
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
199-436 4.49e-24

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 102.78  E-value: 4.49e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752  199 VEIQFHIAHLYETQRKYHSAKAAYEQLLQIEslPSQVKAtvLQQLGWMHHNMdligdnttkERY--AIQYLQKSLEEDPN 276
Cdd:COG0457      8 AEAYNNLGLAYRRLGRYEEAIEDYEKALELD--PDDAEA--LYNLGLAYLRL---------GRYeeALADYEQALELDPD 74

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752  277 SGQSWYFLGRCYSCIGKVQDAFVSYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGILY 356
Cdd:COG0457     75 DAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIAL 154

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752  357 ESCNQPQDAIKCYlNAARSKSCNNTSALTSRIKFLQAQLCNLPQSSLQNKTKLLPSIEEAWSLPIPAELTSRQGAMNTAQ 436
Cdd:COG0457    155 EKLGRYEEALELL-EKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLAL 233
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 165-441 1.35e-22

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 99.03  E-value: 1.35e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752  165 LRLGFMFKMNTDYESSLKHFQLAL-IDcnvctLSSVEIQFHIAHLYETQRKYHSAKAAYEQLLQIEslpsQVKATVLQQL 243
Cdd:COG2956     12 YFKGLNYLLNGQPDKAIDLLEEALeLD-----PETVEAHLALGNLYRRRGEYDRAIRIHQKLLERD----PDRAEALLEL 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752  244 GWMHHNMDLigdnttKERyAIQYLQKSLEEDPNSGQSWYFLGRCYSCIGKVQDAFVSYRQSIDKSEASADTWCSIGVLYQ 323
Cdd:COG2956     83 AQDYLKAGL------LDR-AEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYL 155

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752  324 QQNQPMDALQAYICAVQLDHGHAAAWMDLGILYESCNQPQDAIKCYLNAARSKScNNTSALtSRIKFLQAQLCNLPQ--S 401
Cdd:COG2956    156 EQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDP-DYLPAL-PRLAELYEKLGDPEEalE 233

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|
gi 1031985752  402 SLQNKTKLLPSIEEAWSLpipAELTSRQGAMNTAQQSVSD 441
Cdd:COG2956    234 LLRKALELDPSDDLLLAL---ADLLERKEGLEAALALLER 270
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
122-313 2.17e-19

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 88.91  E-value: 2.17e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752  122 KNAAFLYGLGLVYFYYNAFQWAIRAFQEVLYVDPNFCRAkeiHLRLGFMFKMNTDYESSLKHFQLAL-IDcnvctLSSVE 200
Cdd:COG0457      6 DDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEA---LYNLGLAYLRLGRYEEALADYEQALeLD-----PDDAE 77

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752  201 IQFHIAHLYETQRKYHSAKAAYEQLLQIEslPSQVKAtvLQQLGWMHHNMdligdnttkERY--AIQYLQKSLEEDPNSG 278
Cdd:COG0457     78 ALNNLGLALQALGRYEEALEDYDKALELD--PDDAEA--LYNLGLALLEL---------GRYdeAIEAYERALELDPDDA 144

                          170       180       190
                   ....*....|....*....|....*....|....*
gi 1031985752  279 QSWYFLGRCYSCIGKVQDAFVSYRQSIDKSEASAD 313
Cdd:COG0457    145 DALYNLGIALEKLGRYEEALELLEKLEAAALAALL 179
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 263-369 3.05e-19

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 85.06  E-value: 3.05e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752  263 AIQYLQKSLEEDPNSGQSWYFLGRCYSCIGKVQDAFVSYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLD 342
Cdd:COG4235      2 AIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALD 81

                           90       100
                   ....*....|....*....|....*..
gi 1031985752  343 HGHAAAWMDLGILYESCNQPQDAIKCY 369
Cdd:COG4235     82 PDNPEALYLLGLAAFQQGDYAEAIAAW 108
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
271-372 4.64e-18

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 85.06  E-value: 4.64e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752  271 LEEDPNSGQSWYFLGRCYSCIGKVQDAFVSYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWM 350
Cdd:COG0457      1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALN 80

                           90       100
                   ....*....|....*....|..
gi 1031985752  351 DLGILYESCNQPQDAIKCYLNA 372
Cdd:COG0457     81 NLGLALQALGRYEEALEDYDKA 102
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 67-374 4.96e-18

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 85.55  E-value: 4.96e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752   67 LNKAIHFYESLIVKAEGKVESDFfcQLGHFNLLLEDYSKALSSYQRYYSLQTDywkNAAFLYGLGLVYFYYNAFQWAIRA 146
Cdd:COG2956     24 PDKAIDLLEEALELDPETVEAHL--ALGNLYRRRGEYDRAIRIHQKLLERDPD---RAEALLELAQDYLKAGLLDRAEEL 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752  147 FQEVLYVDPNfcrakeihlrlgfmfkmntdyesslkhfqlalidcnvctlsSVEIQFHIAHLYETQRKYHSAKAAYEQLL 226
Cdd:COG2956     99 LEKLLELDPD-----------------------------------------DAEALRLLAEIYEQEGDWEKAIEVLERLL 137

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752  227 QIeslpSQVKATVLQQLGwmhhnMDLIGDNTTKEryAIQYLQKSLEEDPNSGQSWYFLGRCYSCIGKVQDAFVSYRQSID 306
Cdd:COG2956    138 KL----GPENAHAYCELA-----ELYLEQGDYDE--AIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALE 206

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1031985752  307 KSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGhAAAWMDLGILYESCNQPQDAIKCYLNAAR 374
Cdd:COG2956    207 QDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPS-DDLLLALADLLERKEGLEAALALLERQLR 273
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 263-418 4.23e-17

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 86.59  E-value: 4.23e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752  263 AIQYLQKSLEEDPNSGQSWYFLGRCYSCIGKVQDAFVSYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLD 342
Cdd:COG3914     97 ALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELD 176

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1031985752  343 HGHAAAWMDLGILYESCNQPQDAIKCYLNAARsKSCNNTSALTSRIkFLQAQLCNLPQSS-LQNKTKLLPSIEEAWS 418
Cdd:COG3914    177 PDNAEALNNLGNALQDLGRLEEAIAAYRRALE-LDPDNADAHSNLL-FALRQACDWEVYDrFEELLAALARGPSELS 251
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 263-374 2.75e-15

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 74.07  E-value: 2.75e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752  263 AIQYLQKSLEEDPNSGQSWYFLGRCYSCIGKVQDAFVSYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLD 342
Cdd:COG4783     23 AEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLD 102

                           90       100       110
                   ....*....|....*....|....*....|..
gi 1031985752  343 HGHAAAWMDLGILYESCNQPQDAIKCYLNAAR 374
Cdd:COG4783    103 PEHPEAYLRLARAYRALGRPDEAIAALEKALE 134
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 292-423 2.20e-14

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 77.73  E-value: 2.20e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752  292 GKVQDAFVSYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGILYESCNQPQDAIKCYLN 371
Cdd:COG3914     92 GRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRR 171

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1031985752  372 AARSKScNNTSALTSRIKFLQaQLCNLPQS--SLQNKTKLLPSIEEAWSLPIPA 423
Cdd:COG3914    172 ALELDP-DNAEALNNLGNALQ-DLGRLEEAiaAYRRALELDPDNADAHSNLLFA 223
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 199-342 7.29e-13

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 67.14  E-value: 7.29e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752  199 VEIQFHIAHLYETQRKYHSAKAAYEQLLQIEslPSQVKAtvLQQLGWMHHNMDligdnttKERYAIQYLQKSLEEDPNSG 278
Cdd:COG4783      4 AEALYALAQALLLAGDYDEAEALLEKALELD--PDNPEA--FALLGEILLQLG-------DLDEAIVLLHEALELDPDEP 72

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1031985752  279 QSWYFLGRCYSCIGKVQDAFVSYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLD 342
Cdd:COG4783     73 EARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELD 136
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 66-274 5.16e-12

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 67.83  E-value: 5.16e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752   66 LLNKAIHFYESLIVKAEGKVESdfFCQLGHFNLLLEDYSKALSSYQRYYSLQTDywkNAAFLYGLGLVYFYYNAFQWAIR 145
Cdd:COG2956     91 LLDRAEELLEKLLELDPDDAEA--LRLLAEIYEQEGDWEKAIEVLERLLKLGPE---NAHAYCELAELYLEQGDYDEAIE 165

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752  146 AFQEVLYVDPNFCRAkeiHLRLGFMFKMNTDYESSLKHFQLAL-IDcnvctLSSVEIQFHIAHLYETQRKYHSAKAAYEQ 224
Cdd:COG2956    166 ALEKALKLDPDCARA---LLLLAELYLEQGDYEEAIAALERALeQD-----PDYLPALPRLAELYEKLGDPEEALELLRK 237

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1031985752  225 LLQIESLPSQV--KATVLQQLGwmhhnmdligdnttKERYAIQYLQKSLEED 274
Cdd:COG2956    238 ALELDPSDDLLlaLADLLERKE--------------GLEAALALLERQLRRH 275
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
67-247 1.55e-11

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 65.80  E-value: 1.55e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752   67 LNKAIHFYESLIVKAEGKVESdfFCQLGHFNLLLEDYSKALSSYQRYYSLQTDywkNAAFLYGLGLVYFYYNAFQWAIRA 146
Cdd:COG0457     24 YEEAIEDYEKALELDPDDAEA--LYNLGLAYLRLGRYEEALADYEQALELDPD---DAEALNNLGLALQALGRYEEALED 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752  147 FQEVLYVDPNFCRAkeiHLRLGFMFKMNTDYESSLKHFQLAL-IDCNvctlsSVEIQFHIAHLYETQRKYHSAKAAYEQL 225
Cdd:COG0457     99 YDKALELDPDDAEA---LYNLGLALLELGRYDEAIEAYERALeLDPD-----DADALYNLGIALEKLGRYEEALELLEKL 170

                          170       180
                   ....*....|....*....|..
gi 1031985752  226 LQIESLPSQVKATVLQQLGWMH 247
Cdd:COG0457    171 EAAALAALLAAALGEAALALAA 192
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 92-188 2.41e-10

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 59.63  E-value: 2.41e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752   92 QLGHFNLLLEDYSKALSSYQRYYSLQTDywkNAAFLYGLGLVYFYYNAFQWAIRAFQEVLYVDPNFCRAkeiHLRLGFMF 171
Cdd:COG4235     22 LLGRAYLRLGRYDEALAAYEKALRLDPD---NADALLDLAEALLAAGDTEEAEELLERALALDPDNPEA---LYLLGLAA 95

                           90
                   ....*....|....*..
gi 1031985752  172 KMNTDYESSLKHFQLAL 188
Cdd:COG4235     96 FQQGDYAEAIAAWQKLL 112
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 120-369 1.07e-09

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 62.70  E-value: 1.07e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752  120 YWKNAAFLYGLGLVYFYYNAFQWAIRAFQEVLYVDPNFCRAKEIHLRLgfmFKMNTDYESSLKHFQLAL-IDCNvctlsS 198
Cdd:COG3914     40 ALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALL---LQALGRYEEALALYRRALaLNPD-----N 111

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752  199 VEIQFHIAHLYETQRKYHSAKAAYEQLLQIEslPSQVKAtvLQQLGWMHHNMDLIGDnttkeryAIQYLQKSLEEDPNSG 278
Cdd:COG3914    112 AEALFNLGNLLLALGRLEEALAALRRALALN--PDFAEA--YLNLGEALRRLGRLEE-------AIAALRRALELDPDNA 180

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752  279 QSWYFLGRCYSCIGKVQDAFVSYRQSIDKsEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGILYES 358
Cdd:COG3914    181 EALNNLGNALQDLGRLEEAIAAYRRALEL-DPDNADAHSNLLFALRQACDWEVYDRFEELLAALARGPSELSPFALLYLP 259

                          250
                   ....*....|.
gi 1031985752  359 CNQPQDAIKCY 369
Cdd:COG3914    260 DDDPAELLALA 270
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 279-374 4.96e-09

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 55.97  E-value: 4.96e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752  279 QSWYFLGRCYSCIGKVQDAFVSYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGILYES 358
Cdd:COG4783      5 EALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLK 84

                           90
                   ....*....|....*.
gi 1031985752  359 CNQPQDAIKCYLNAAR 374
Cdd:COG4783     85 AGDYDEALALLEKALK 100
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
263-342 5.74e-09

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 54.41  E-value: 5.74e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752  263 AIQYLQKSLEEDPNSGQSWYFLGRCYSCIGKVQDAfVSYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLD 342
Cdd:COG3063     11 AEEYYEKALELDPDNADALNNLGLLLLEQGRYDEA-IALEKALKLDPNNAEALLNLAELLLELGDYDEALAYLERALELD 89
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
274-367 7.35e-09

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 57.62  E-value: 7.35e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752  274 DPNSGQSWYFLGRCYSCIGKVQDAFVSYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLG 353
Cdd:COG4785     69 LPDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRG 148

                           90
                   ....*....|....
gi 1031985752  354 ILYESCNQPQDAIK 367
Cdd:COG4785    149 IALYYLGRYELAIA 162
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 263-342 8.96e-09

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 55.74  E-value: 8.96e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752  263 AIQYLQKSLEEDPNSGQSWYFLGRCYSCIGKVQDAFVSYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLD 342
Cdd:COG5010     73 SLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTS 152
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 280-394 1.16e-08

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 57.82  E-value: 1.16e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752  280 SWYFLGRCYSCIGKVQDAFVSYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGILYESC 359
Cdd:COG2956     10 GWYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKA 89

                           90       100       110
                   ....*....|....*....|....*....|....*
gi 1031985752  360 NQPQDAIKCYLNAARSKScNNTSALTSRIKFLQAQ 394
Cdd:COG2956     90 GLLDRAEELLEKLLELDP-DDAEALRLLAEIYEQE 123
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 263-375 1.65e-08

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 54.97  E-value: 1.65e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752  263 AIQYLQKSLEEDPNSGQSWYFLGRCYSCIGKVQDAFVSYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLD 342
Cdd:COG5010     39 EDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALS 118

                           90       100       110
                   ....*....|....*....|....*....|...
gi 1031985752  343 HGHAAAWMDLGILYESCNQPQDAIKCYLNAARS 375
Cdd:COG5010    119 PDNPNAYSNLAALLLSLGQDDEAKAALQRALGT 151
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 124-277 3.76e-08

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 53.66  E-value: 3.76e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752  124 AAFLYGLGLVYFYYNAFQWAIRAFQEVLYVDPNFCRAkeiHLRLGFMFKMNTDYESSLKHFQLALIDCNvctlSSVEIQF 203
Cdd:COG4783      4 AEALYALAQALLLAGDYDEAEALLEKALELDPDNPEA---FALLGEILLQLGDLDEAIVLLHEALELDP----DEPEARL 76

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1031985752  204 HIAHLYETQRKYHSAKAAYEQLLQIEslPSQvkATVLQQLGWMHHNMDligdnttKERYAIQYLQKSLEEDPNS 277
Cdd:COG4783     77 NLGLALLKAGDYDEALALLEKALKLD--PEH--PEAYLRLARAYRALG-------RPDEAIAALEKALELDPDD 139
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 67-188 6.44e-08

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 52.89  E-value: 6.44e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752   67 LNKAIHFYESLIvkAEGKVESDFFCQLGHFNLLLEDYSKALSSYQRYYSLQTDywkNAAFLYGLGLVYFYYNAFQWAIRA 146
Cdd:COG4783     20 YDEAEALLEKAL--ELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPD---EPEARLNLGLALLKAGDYDEALAL 94

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|..
gi 1031985752  147 FQEVLYVDPNFcraKEIHLRLGFMFKMNTDYESSLKHFQLAL 188
Cdd:COG4783     95 LEKALKLDPEH---PEAYLRLARAYRALGRPDEAIAALEKAL 133
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 198-313 8.85e-08

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 52.32  E-value: 8.85e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752  198 SVEIQFHIAHLYETQRKYHSAKAAYEQLLQIEslPSqvKATVLQQLGWMHHNMDligdNTTKeryAIQYLQKSLEEDPNS 277
Cdd:COG4235     16 DAEGWLLLGRAYLRLGRYDEALAAYEKALRLD--PD--NADALLDLAEALLAAG----DTEE---AEELLERALALDPDN 84

                           90       100       110
                   ....*....|....*....|....*....|....*.
gi 1031985752  278 GQSWYFLGRCYSCIGKVQDAFVSYRQSIDKSEASAD 313
Cdd:COG4235     85 PEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAP 120
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
292-374 3.73e-07

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 49.40  E-value: 3.73e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752  292 GKVQDAFVSYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQaYICAVQLDHGHAAAWMDLGILYESCNQPQDAIKCYLN 371
Cdd:COG3063      6 GDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEALAYLER 84


                   ...
gi 1031985752  372 AAR 374
Cdd:COG3063     85 ALE 87
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 122-243 1.32e-06

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 48.85  E-value: 1.32e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752  122 KNAAFLYGLGLVYFYYNAFQWAIRAFQEVLYVDPNFcraKEIHLRLGFMFKMNTDYESSLKHFQLAL-IDCNvctlsSVE 200
Cdd:COG4235     15 NDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDN---ADALLDLAEALLAAGDTEEAEELLERALaLDPD-----NPE 86

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|...
gi 1031985752  201 IQFHIAHLYETQRKYHSAKAAYEQLLQIesLPSQVKATVLQQL 243
Cdd:COG4235     87 ALYLLGLAAFQQGDYAEAIAAWQKLLAL--LPADAPARLLEAS 127
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 98-231 5.64e-06

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 47.65  E-value: 5.64e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752   98 LLLEDYSKALSSYQRYYSLQTDYWKNAAFLYGLGLVYFYYNAFQWAIRAFQEVLYVDPNFcraKEIHLRLGFMFKMNTDY 177
Cdd:COG5010     28 EAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNN---PELYYNLALLYSRSGDK 104

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1031985752  178 ESSLKHFQLALIDCNvctlSSVEIQFHIAHLYETQRKYHSAKAAYEQLLQIESL 231
Cdd:COG5010    105 DEAKEYYEKALALSP----DNPNAYSNLAALLLSLGQDDEAKAALQRALGTSPL 154
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
90-160 8.08e-06

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 48.37  E-value: 8.08e-06
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1031985752   90 FCQLGHFNLLLEDYSKALSSYQRYYSLQTDYwknAAFLYGLGLVYFYYNAFQWAIRAFQEVLYVDPNFCRA 160
Cdd:COG4785    110 YNNRGLAYLLLGDYDAALEDFDRALELDPDY---AYAYLNRGIALYYLGRYELAIADLEKALELDPNDPER 177
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 98-369 1.08e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 49.70  E-value: 1.08e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752   98 LLLEDYSKALSSYQRYYSLQTDywkNAAFLYGLGLVYFYYNAFQWAIRAFQEVLYVDPNFCRAkeiHLRLGfMFKM---- 173
Cdd:TIGR02917  340 LRLGRVDEAIATLSPALGLDPD---DPAALSLLGEAYLALGDFEKAAEYLAKATELDPENAAA---RTQLG-ISKLsqgd 412

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752  174 ------------NTDYESSLKHFQLAL-------IDCNVCTLSSVE--------IQFHIAHLYETQRKYHSAKAAYEQLL 226
Cdd:TIGR02917  413 pseaiadletaaQLDPELGRADLLLILsylrsgqFDKALAAAKKLEkkqpdnasLHNLLGAIYLGKGDLAKAREAFEKAL 492

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752  227 QIEslPSQVKATVLQQlgwmhhNMDLIGDNTTKeryAIQYLQKSLEEDPNSGQSWYFLGRCYSCIGKVQDAFVSYRQSID 306
Cdd:TIGR02917  493 SIE--PDFFPAAANLA------RIDIQEGNPDD---AIQRFEKVLTIDPKNLRAILALAGLYLRTGNEEEAVAWLEKAAE 561

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1031985752  307 KSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGILYESCNQPQDAIKCY 369
Cdd:TIGR02917  562 LNPQEIEPALALAQYYLGKGQLKKALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSF 624
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 92-280 2.63e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 48.54  E-value: 2.63e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752   92 QLGHFNLLLEDySKALSSYQRYYSLQTDYWKNAAFLYGLGLVYFYYNAFQWAIRAFQEVLYVDP---NFCRAKEIHLRLG 168
Cdd:TIGR02917  672 QIGLAQLLLAA-KRTESAKKIAKSLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKALKRAPssqNAIKLHRALLASG 750

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752  169 FMFKMNTDYESSLKhfqlalIDCNvctlsSVEIQFHIAHLYETQRKYHSAKAAYEQLLQIEslPSQvkATVLQQLGWMHH 248
Cdd:TIGR02917  751 NTAEAVKTLEAWLK------THPN-----DAVLRTALAELYLAQKDYDKAIKHYQTVVKKA--PDN--AVVLNNLAWLYL 815

                          170       180       190
                   ....*....|....*....|....*....|..
gi 1031985752  249 NMdligdnttKERYAIQYLQKSLEEDPNSGQS 280
Cdd:TIGR02917  816 EL--------KDPRALEYAERALKLAPNIPAI 839
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
133-229 4.67e-05

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 43.24  E-value: 4.67e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752  133 VYFYYNAFQWAIRAFQEVLYVDPNFCRAkeiHLRLGFMFKMNTDYESSLKhFQLAL-IDCNvctlsSVEIQFHIAHLYET 211
Cdd:COG3063      1 LYLKLGDLEEAEEYYEKALELDPDNADA---LNNLGLLLLEQGRYDEAIA-LEKALkLDPN-----NAEALLNLAELLLE 71

                           90
                   ....*....|....*...
gi 1031985752  212 QRKYHSAKAAYEQLLQIE 229
Cdd:COG3063     72 LGDYDEALAYLERALELD 89
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 263-335 4.82e-05

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 43.83  E-value: 4.82e-05
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1031985752  263 AIQYLQKSLEEDPNS---GQSWYFLGRCYSCIGKVQDAFVSYRQSID---KSEASADTWCSIGVLYQQQNQPMDALQAY 335
Cdd:COG1729     12 AIAAFKAFLKRYPNSplaPDALYWLGEAYYALGDYDEAAEAFEKLLKrypDSPKAPDALLKLGLSYLELGDYDKARATL 90
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 102-188 5.21e-05

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 43.83  E-value: 5.21e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752  102 DYSKALSSYQRYYSL--QTDYWKNAafLYGLGLVYFYYNAFQWAIRAFQEVLYVDPNFCRAKEIHLRLGFMFKMNTDYES 179
Cdd:COG1729      8 DYDEAIAAFKAFLKRypNSPLAPDA--LYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKAPDALLKLGLSYLELGDYDK 85


                   ....*....
gi 1031985752  180 SLKHFQLAL 188
Cdd:COG1729     86 ARATLEELI 94
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 67-155 1.07e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 43.80  E-value: 1.07e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752   67 LNKAIHFYESLIVKAEGkvESDFFCQLGHFNLLLEDYSKALSSYQRYYSLQTDywkNAAFLYGLGLVYFYYNAFQWAIRA 146
Cdd:COG5010     70 FEESLALLEQALQLDPN--NPELYYNLALLYSRSGDKDEAKEYYEKALALSPD---NPNAYSNLAALLLSLGQDDEAKAA 144


                   ....*....
gi 1031985752  147 FQEVLYVDP 155
Cdd:COG5010    145 LQRALGTSP 153
MamA NF040959
magnetosome protein MamA; Magnetosomes are special lipid-bound organelles that comprise ...
 100-188 1.63e-04

magnetosome protein MamA; Magnetosomes are special lipid-bound organelles that comprise magnetic mineral crystals in magnetotactic bacteria (MTB). Magnetosomes are important for MTB to search for preferred microaerophilic environment. Proteins of this family typically contain five tetra-trico-peptide repeat (TPR) motifs. Based on structural analyses, MamA forms a large homooligomer through self-recognition to regulate protein-protein interaction in magnetosomes.


Pssm-ID: 468889 [Multi-domain]  Cd Length: 204  Bit Score: 44.29  E-value: 1.63e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752  100 LEDYSKALSSYQRYYSLQTDywkNAAFLYGLGLVYFYYNAFQWAIRAFQEVLYVDPNFCRakeIHLRLGFMFKMNTDYES 179
Cdd:NF040959   118 IKDYEKAVEDLEEALEEKPD---NFNLNYRLGLALDGLGQYDKAIEAFQKALELDPNEIK---YHQAIGFMYVQKGDHET 191


                   ....*....
gi 1031985752  180 SLKHFQLAL 188
Cdd:NF040959   192 AAEHFKKAM 200
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 93-372 2.10e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 45.84  E-value: 2.10e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752   93 LGHFNLLLEDYSKALSSYQRYYSLQTDywkNAAFLYGLGLVYFYYNAFQWAIRAFQEVLYVDPNFCRAKeihLRLGFMFK 172
Cdd:TIGR02917  607 LGRAQLAAGDLNKAVSSFKKLLALQPD---SALALLLLADAYAVMKNYAKAITSLKRALELKPDNTEAQ---IGLAQLLL 680

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752  173 MNTDYESSLKHFQlaliDCNVCTLSSVEIQFHIAHLYETQRKYHSAKAAYEQLLQIESLPSQVK--ATVLQQLGwmhhnm 250
Cdd:TIGR02917  681 AAKRTESAKKIAK----SLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKALKRAPSSQNAIklHRALLASG------ 750

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752  251 dligdNTTKeryAIQYLQKSLEEDPNSGQSWYFLGRCYSCIGKVQDAFVSYRQSIDKSEASADTWCSIGVLYQQQNQPmD 330
Cdd:TIGR02917  751 -----NTAE---AVKTLEAWLKTHPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKKAPDNAVVLNNLAWLYLELKDP-R 821

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|...
gi 1031985752  331 ALQAYICAVQLDHGhAAAWMD-LGILYESCNQPQDAIKCYLNA 372
Cdd:TIGR02917  822 ALEYAERALKLAPN-IPAILDtLGWLLVEKGEADRALPLLRKA 863
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 321-394 2.22e-04

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 45.37  E-value: 2.22e-04
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1031985752  321 LYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGILYESCNQPQDAIKCYLNAARSKScNNTSALTSRIKFLQAQ 394
Cdd:COG3914     87 LLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNP-DFAEAYLNLGEALRRL 159
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 159-369 3.15e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 45.07  E-value: 3.15e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752  159 RAKEIHLRLGFMFKMNTDYESSLKHFQ-LALIDCNvctlsSVEIQFHIAHLYETQRKYHSAKAAYEQLLQIEslPSQVKA 237
Cdd:TIGR02917  599 DSPEAWLMLGRAQLAAGDLNKAVSSFKkLLALQPD-----SALALLLLADAYAVMKNYAKAITSLKRALELK--PDNTEA 671

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752  238 TVLQ-QLgwmhhnmdLIGDNTTKERYAI-QYLQKSLEEDPnSGQSwyFLGRCYSCIGKVQDAFVSYRQSIdKSEASADTW 315
Cdd:TIGR02917  672 QIGLaQL--------LLAAKRTESAKKIaKSLQKQHPKAA-LGFE--LEGDLYLRQKDYPAAIQAYRKAL-KRAPSSQNA 739

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1031985752  316 CSIGVLYQQQNQPMDALQAYIcAVQLDH-GHAAAWMDLGILYESCNQPQDAIKCY 369
Cdd:TIGR02917  740 IKLHRALLASGNTAEAVKTLE-AWLKTHpNDAVLRTALAELYLAQKDYDKAIKHY 793
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 105-275 3.36e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 42.64  E-value: 3.36e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752  105 KALSSYQRYYSLQTDYWKNAAFLYGLGLVYFYYNAFQWAIRAFQEVLYVDPNFCRAKEIHLRLGfmfkmntDYESSLKHF 184
Cdd:COG5010      5 EGFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLG-------DFEESLALL 77

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752  185 QLAL-IDCNvctlsSVEIQFHIAHLYETQRKYHSAKAAYEQLLQIEslPSQVKAtvlqqlgwmHHNMDLIGDNTTKERYA 263
Cdd:COG5010     78 EQALqLDPN-----NPELYYNLALLYSRSGDKDEAKEYYEKALALS--PDNPNA---------YSNLAALLLSLGQDDEA 141

                          170
                   ....*....|..
gi 1031985752  264 IQYLQKSLEEDP 275
Cdd:COG5010    142 KAALQRALGTSP 153
TPR_1 pfam00515
Tetratricopeptide repeat;
124-157 4.60e-04

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 38.56  E-value: 4.60e-04
                           10        20        30
                   ....*....|....*....|....*....|....
gi 1031985752  124 AAFLYGLGLVYFYYNAFQWAIRAFQEVLYVDPNF 157
Cdd:pfam00515    1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
JmjC smart00558
A domain family that is part of the cupin metalloenzyme superfamily; Probable enzymes, but of ...
 910-974 4.77e-04

A domain family that is part of the cupin metalloenzyme superfamily; Probable enzymes, but of unknown functions, that regulate chromatin reorganisation processes (Clissold and Ponting, in press).


Pssm-ID: 214721  Cd Length: 58  Bit Score: 39.16  E-value: 4.77e-04
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1031985752   910 QLHELTKLPafvrvvSAGNLLSHVGYTILGMNSVQLC-MKVPGSRIPGHQENNNfcSVNINIGPGD 974
Cdd:smart00558    1 QLWNLAKLP------FKLNLLSDLPEDIPGPDVGPYLyMGMAGSTTPWHIDDYD--LVNYLHQGAG 58
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 198-344 6.18e-04

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 43.36  E-value: 6.18e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752  198 SVEIQFHIAHLYETQRKYHSAkaayEQLLQiESLPSQVKATVLQQLGwmhhnmDLIGDNTTKeryAIQYLQKSLEEDPNS 277
Cdd:COG3071    192 DPELAAAYARALIALGDHDEA----ERLLR-EALKRQWDPRLVRLYG------RLQGGDPAK---QLKRAEKWLKKHPND 257

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752  278 GQSWYFLGR-CYSC--IGKVQDAFvsyRQSIdKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHG 344
Cdd:COG3071    258 PDLLLALGRlCLRNqlWGKAREYL---EAAL-ALRPSAEAYAELARLLEQLGDPEEAAEHYRKALALALG 323
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
100-188 6.32e-04

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 42.59  E-value: 6.32e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752  100 LEDYSKALSSYQRYYSLQTDYwknAAFLYGLGLVYFYYNAFQWAIRAFQEVLYVDPNFCRAkeiHLRLGFMFKMNTDYES 179
Cdd:COG4785     86 LGDYDLAIADFDQALELDPDL---AEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYA---YLNRGIALYYLGRYEL 159


                   ....*....
gi 1031985752  180 SLKHFQLAL 188
Cdd:COG4785    160 AIADLEKAL 168
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
321-394 9.82e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 39.77  E-value: 9.82e-04
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1031985752  321 LYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGILYESCNQPQDAIKcyLNAARSKSCNNTSALTSRIKFLQAQ 394
Cdd:COG3063      1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA--LEKALKLDPNNAEALLNLAELLLEL 72
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
263-363 2.91e-03

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 40.67  E-value: 2.91e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752  263 AIQYLQKSLEEDPNSGQSWYFLGRCYSCIGKVQDAFVSYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLD 342
Cdd:COG4785     92 AIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYELAIADLEKALELD 171

                           90       100
                   ....*....|....*....|.
gi 1031985752  343 HGHAAAWMDLGILYESCNQPQ 363
Cdd:COG4785    172 PNDPERALWLYLAERKLDPEK 192
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
67-159 3.20e-03

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 38.23  E-value: 3.20e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752   67 LNKAIHFYESLIVKAEGkvESDFFCQLGHFNLLLEDYSKALSsYQRYYSLQTDywkNAAFLYGLGLVYFYYNAFQWAIRA 146
Cdd:COG3063      8 LEEAEEYYEKALELDPD--NADALNNLGLLLLEQGRYDEAIA-LEKALKLDPN---NAEALLNLAELLLELGDYDEALAY 81

                           90
                   ....*....|...
gi 1031985752  147 FQEVLYVDPNFCR 159
Cdd:COG3063     82 LERALELDPSALR 94
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 92-156 5.14e-03

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 38.05  E-value: 5.14e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1031985752   92 QLGHFNLLLEDYSKALSSYQRYYSLQTDYWKNAAFLYGLGLVYFYYNAFQWAIRAFQEVLYVDPN 156
Cdd:COG1729     35 WLGEAYYALGDYDEAAEAFEKLLKRYPDSPKAPDALLKLGLSYLELGDYDKARATLEELIKKYPD 99
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 134-227 9.55e-03

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 37.28  E-value: 9.55e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752  134 YFYYNAFQWAIRAFQEVLYVDPNFCRAKEIHLRLGFMFKMNTDYESSLKHFQlALIDCNVCTLSSVEIQFHIAHLYETQR 213
Cdd:COG1729      3 LLKAGDYDEAIAAFKAFLKRYPNSPLAPDALYWLGEAYYALGDYDEAAEAFE-KLLKRYPDSPKAPDALLKLGLSYLELG 81

                           90
                   ....*....|....
gi 1031985752  214 KYHSAKAAYEQLLQ 227
Cdd:COG1729     82 DYDKARATLEELIK 95
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 309-394 9.84e-03

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 37.86  E-value: 9.84e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031985752  309 EASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGILYESCNQPQDAIKcYLNAARSKSCNNTSALTSRI 388
Cdd:COG4783      1 AACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIV-LLHEALELDPDEPEARLNLG 79


                   ....*.
gi 1031985752  389 KFLQAQ 394
Cdd:COG4783     80 LALLKA 85
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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