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Conserved domains on  [gi|1047401540|ref|NP_001316681|]
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protein FAM136A isoform 2 [Homo sapiens]

Protein Classification

FAM136 family protein( domain architecture ID 10530719)

FAM136 family protein is a DUF842 domain-containing protein similar to Homo sapiens protein FAM136A

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF842 pfam05811
Eukaryotic protein of unknown function (DUF842); This family consists of a number of conserved ...
 132-234 7.94e-45

Eukaryotic protein of unknown function (DUF842); This family consists of a number of conserved eukaryotic proteins of unknown function. The sequences carry three sets of CxxxC motifs, which might suggest a type of zinc-finger formation.


:

Pssm-ID: 461747  Cd Length: 126  Bit Score: 146.66  E-value: 7.94e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047401540 132 RPLpQGLMFRCSASCCEDSQASMKQVHQCIERCHVPLAQAQALVTSELEKFQDRLARCTMHCNDKAKDSIDAGSKELQVK 211
Cdd:pfam05811  22 RKL-QKDMFKCAAKCCDDRDASQEEVQNCVERCSQPLTKAQNYVQNELEQFQERLQRCVMVCQDKAKDKFGPNPSEKDVA 100

                          90       100
                  ....*....|....*....|....*.
gi 1047401540 212 ---QQLDSCVTKCVDDHMHLIPTMTK 234
Cdd:pfam05811 101 kaqKQLESCVVKCVDEHIKLLPKIVK 126
 
Name Accession Description Interval E-value
DUF842 pfam05811
Eukaryotic protein of unknown function (DUF842); This family consists of a number of conserved ...
 132-234 7.94e-45

Eukaryotic protein of unknown function (DUF842); This family consists of a number of conserved eukaryotic proteins of unknown function. The sequences carry three sets of CxxxC motifs, which might suggest a type of zinc-finger formation.


Pssm-ID: 461747  Cd Length: 126  Bit Score: 146.66  E-value: 7.94e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047401540 132 RPLpQGLMFRCSASCCEDSQASMKQVHQCIERCHVPLAQAQALVTSELEKFQDRLARCTMHCNDKAKDSIDAGSKELQVK 211
Cdd:pfam05811  22 RKL-QKDMFKCAAKCCDDRDASQEEVQNCVERCSQPLTKAQNYVQNELEQFQERLQRCVMVCQDKAKDKFGPNPSEKDVA 100

                          90       100
                  ....*....|....*....|....*.
gi 1047401540 212 ---QQLDSCVTKCVDDHMHLIPTMTK 234
Cdd:pfam05811 101 kaqKQLESCVVKCVDEHIKLLPKIVK 126
 
Name Accession Description Interval E-value
DUF842 pfam05811
Eukaryotic protein of unknown function (DUF842); This family consists of a number of conserved ...
 132-234 7.94e-45

Eukaryotic protein of unknown function (DUF842); This family consists of a number of conserved eukaryotic proteins of unknown function. The sequences carry three sets of CxxxC motifs, which might suggest a type of zinc-finger formation.


Pssm-ID: 461747  Cd Length: 126  Bit Score: 146.66  E-value: 7.94e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1047401540 132 RPLpQGLMFRCSASCCEDSQASMKQVHQCIERCHVPLAQAQALVTSELEKFQDRLARCTMHCNDKAKDSIDAGSKELQVK 211
Cdd:pfam05811  22 RKL-QKDMFKCAAKCCDDRDASQEEVQNCVERCSQPLTKAQNYVQNELEQFQERLQRCVMVCQDKAKDKFGPNPSEKDVA 100

                          90       100
                  ....*....|....*....|....*.
gi 1047401540 212 ---QQLDSCVTKCVDDHMHLIPTMTK 234
Cdd:pfam05811 101 kaqKQLESCVVKCVDEHIKLLPKIVK 126
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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