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Conserved domains on  [gi|1270530299|ref|NP_001344357|]
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immunoglobulin-like domain-containing receptor 2 isoform 2 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LSR super family cl09579
Lipolysis stimulated receptor (LSR); The lipolysis-stimulated receptor (LSR) is a lipoprotein ...
 201-227 2.35e-05

Lipolysis stimulated receptor (LSR); The lipolysis-stimulated receptor (LSR) is a lipoprotein receptor primarily expressed in the liver and activated by free fatty acids. It is thought to be involved in the clearance of triglyceride-rich lipoproteins, and has been shown in mice to be critical for liver and embryonic development.


The actual alignment was detected with superfamily member pfam05624:

Pssm-ID: 428550  Cd Length: 48  Bit Score: 42.04  E-value: 2.35e-05
                          10        20
                  ....*....|....*....|....*..
gi 1270530299 201 EWVFVGLVILGIFLFFVLVGICWCQCC 227
Cdd:pfam05624   1 HWLFVLLVVLGGLLLLLLIGICWCQCC 27
V-set super family cl46292
Immunoglobulin V-set domain; This domain is found in antibodies as well as neural protein P0 ...
 132-181 5.41e-03

Immunoglobulin V-set domain; This domain is found in antibodies as well as neural protein P0 and CTL4 amongst others.


The actual alignment was detected with superfamily member pfam07686:

Pssm-ID: 462230  Cd Length: 109  Bit Score: 37.05  E-value: 5.41e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 1270530299 132 YRGREITIVHDADLQIGKLMWGDSGLYYCIITTPDdlEGKNEDSVELLVL 181
Cdd:pfam07686  62 FSGRGDPSNGDGSLTIQNLTLSDSGTYTCAVIPSG--EGVFGKGTRLTVL 109
 
Name Accession Description Interval E-value
LSR pfam05624
Lipolysis stimulated receptor (LSR); The lipolysis-stimulated receptor (LSR) is a lipoprotein ...
 201-227 2.35e-05

Lipolysis stimulated receptor (LSR); The lipolysis-stimulated receptor (LSR) is a lipoprotein receptor primarily expressed in the liver and activated by free fatty acids. It is thought to be involved in the clearance of triglyceride-rich lipoproteins, and has been shown in mice to be critical for liver and embryonic development.


Pssm-ID: 428550  Cd Length: 48  Bit Score: 42.04  E-value: 2.35e-05
                          10        20
                  ....*....|....*....|....*..
gi 1270530299 201 EWVFVGLVILGIFLFFVLVGICWCQCC 227
Cdd:pfam05624   1 HWLFVLLVVLGGLLLLLLIGICWCQCC 27
V-set pfam07686
Immunoglobulin V-set domain; This domain is found in antibodies as well as neural protein P0 ...
 132-181 5.41e-03

Immunoglobulin V-set domain; This domain is found in antibodies as well as neural protein P0 and CTL4 amongst others.


Pssm-ID: 462230  Cd Length: 109  Bit Score: 37.05  E-value: 5.41e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 1270530299 132 YRGREITIVHDADLQIGKLMWGDSGLYYCIITTPDdlEGKNEDSVELLVL 181
Cdd:pfam07686  62 FSGRGDPSNGDGSLTIQNLTLSDSGTYTCAVIPSG--EGVFGKGTRLTVL 109
 
Name Accession Description Interval E-value
LSR pfam05624
Lipolysis stimulated receptor (LSR); The lipolysis-stimulated receptor (LSR) is a lipoprotein ...
 201-227 2.35e-05

Lipolysis stimulated receptor (LSR); The lipolysis-stimulated receptor (LSR) is a lipoprotein receptor primarily expressed in the liver and activated by free fatty acids. It is thought to be involved in the clearance of triglyceride-rich lipoproteins, and has been shown in mice to be critical for liver and embryonic development.


Pssm-ID: 428550  Cd Length: 48  Bit Score: 42.04  E-value: 2.35e-05
                          10        20
                  ....*....|....*....|....*..
gi 1270530299 201 EWVFVGLVILGIFLFFVLVGICWCQCC 227
Cdd:pfam05624   1 HWLFVLLVVLGGLLLLLLIGICWCQCC 27
V-set pfam07686
Immunoglobulin V-set domain; This domain is found in antibodies as well as neural protein P0 ...
 132-181 5.41e-03

Immunoglobulin V-set domain; This domain is found in antibodies as well as neural protein P0 and CTL4 amongst others.


Pssm-ID: 462230  Cd Length: 109  Bit Score: 37.05  E-value: 5.41e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 1270530299 132 YRGREITIVHDADLQIGKLMWGDSGLYYCIITTPDdlEGKNEDSVELLVL 181
Cdd:pfam07686  62 FSGRGDPSNGDGSLTIQNLTLSDSGTYTCAVIPSG--EGVFGKGTRLTVL 109
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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