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Conserved domains on  [gi|1435761102|ref|NP_001352055|]
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nuclear pore complex protein Nup98-Nup96 isoform 6 precursor [Homo sapiens]

Protein Classification

Nucleoporin2 and Nup96 domain-containing protein( domain architecture ID 13837547)

Nucleoporin2 and Nup96 domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Nup96 pfam12110
Nuclear protein 96; Nup96 (often known by the name of its yeast homolog Nup145C) is part of ...
 1332-1623 4.79e-134

Nuclear protein 96; Nup96 (often known by the name of its yeast homolog Nup145C) is part of the Nup84 heptameric complex in the nuclear pore complex. Nup96 complexes with Sec13 in the middle of the heptamer. The function of the heptamer is to coat the curvature of the nuclear pore complex between the inner and outer nuclear membranes. Nup96 is predicted to be an alpha helical solenoid. The interaction between Nup96 and Sec13 is the point of curvature in the heptameric complex.


:

Pssm-ID: 463462  Cd Length: 287  Bit Score: 418.92  E-value: 4.79e-134
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102 1332 EAVFSYLTGKRISEACSLAQQSGDHRLALLLSQFVGSQSVRELLTMQLVDWHQLQADSFIQDERLRIFALLAGKPVWQLS 1411
Cdd:pfam12110    1 EKAFALLTGHRVEEACELAIDSGDFRLATLLSQAGGDDSFREDMAEQLDDWRESGVDSEIDEPRRKLYELLAGNVLVSEG 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102 1412 EKKQINVCSQLDWKRSLAIHLWYLLPPTASISRALSMYEEAFQntsdSDRYACSPLPSYLEGSGCVIAEEQNSQTPLrDV 1491
Cdd:pfam12110   81 KKSTINISEGLDWKRAFGLRLWYGIPPDTSIEDAVEAYEEALS----QGREPAPPLPWYLEEGDSESWEDPRLKKRE-DL 155

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102 1492 CFHLLKLYSDRHYDLNQLLEPRSITADPLDYRLSWHLWEVLRA--LNYTHLSAQCEGVLQASYAGQLESEGLWEWAIFVL 1569
Cdd:pfam12110  156 LYHLLKLYADPTAPLEAVLDPESSSPDPLDYRLSWHLYQVLSAvrLGYGHLSSAKADQLTLSFASQLESLGLWQWAVFVL 235

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1435761102 1570 LHIDNSGIREKAVRELLTRHCQLLETPESwaKETFLTQKLRVPAKWIHEAKAVR 1623
Cdd:pfam12110  236 LHLEDPARRERAVRELLARHAELISEDDA--KERFLTEKLKIPEAWIHEAKALY 287
Nucleoporin2 pfam04096
Nucleoporin autopeptidase; The nuclear pore complex protein plays a role in bidirectional ...
 738-880 2.62e-63

Nucleoporin autopeptidase; The nuclear pore complex protein plays a role in bidirectional transport across the nucleoporin complex in nucleocytoplasmic transport. The mammalian nuclear pore complex (NPC) is comprised of approximately 30 unique proteins, collectively known as nucleoporins. This family includes yeast family members such as Nup145p as well as vertebrate Nup98. The NUP C-terminal domains of Nup98 and Nup145 possess peptidase S59 autoproteolytic activity. The autoproteolytic sites of Nup98 and Nup145 each occur immediately C-terminal to the NUP C-terminal domain. Thus, although this domain occurs in the middle of each precursor polypeptide, it winds up at the C-terminal end of the N-terminal cleavage product. Cleavage of the peptide chains are necessary for the proper targeting to the nuclear pore.


:

Pssm-ID: 461171  Cd Length: 143  Bit Score: 211.97  E-value: 2.62e-63
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  738 KVGYYTIPSMDDLAKITnEKGECIVSDFTIGRKGYGSIYFEGDVNLTNLNLDDI----VHIRRKEVVVYLDDNQKPPVGE 813
Cdd:pfam04096    1 KGDYWTSPSLEELKKMS-REQLSSVENFTVGRKGYGSVRFLGPVDLTGLDLDEIfgkiVKFEPREVTVYPDESSKPPVGQ 79

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1435761102  814 GLNRKAEVTLDGVWPTDKTSRCLIKSPDRLADINYEGRLEavsRKQGAQFKEYRPETGSWVFKVSHF 880
Cdd:pfam04096   80 GLNVPATITLENVWPRDKDTKEPIKDPSGPRLEKHIERLK---RVQGTEFVSYDPETGTWTFKVEHF 143
COG4625 COG4625
Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function ...
 25-452 4.25e-16

Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function unknown];


:

Pssm-ID: 443664 [Multi-domain]  Cd Length: 900  Bit Score: 84.44  E-value: 4.25e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102   25 QNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSS 104
Cdd:COG4625     74 AGGGGGGGGGGGGGGGTGGVGGGGGGGGGGGGGGGGGGGGGGGGSAGGGGGGAGGAGGGGGGGAGGGGGGGGGGGAGGGG 153

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  105 QNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISt 184
Cdd:COG4625    154 GGGAGGAGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGNGGGGGGGGGGGGGGGGGGGGAGGGGGGGGGGGGGGGGGG- 232

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  185 khqcitamkeyeskSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQNKTAFGTSTT 264
Cdd:COG4625    233 --------------GGGGGGGGGGGGGGGAGGGGGGGGGNGGGGGAGGGGGGGGGGSGGGGGGGGGGGSGGGGGGGGGGG 298

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  265 GFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGqpstNTMGLFGVTQASQPGGLFGTATNTSTGTAFG 344
Cdd:COG4625    299 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGAGGGGGSGGA----GAGGGGAGGGGAGGGGGGGTGGGGGGGGGGG 374

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  345 TGTGLFGQTNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNFGFGTNTSGNSIFGSKP 424
Cdd:COG4625    375 GGSGGGGAGGGGGSGGGGGGGAGGGGGGGGAGGTGGGGAGGGGGAAGGGGGGTGAGGGGGGGGTGAGGGGATGGGGGGGG 454

                          410       420
                   ....*....|....*....|....*...
gi 1435761102  425 APGTLGTGLGAGFGTALGAGQASLFGNN 452
Cdd:COG4625    455 GAGGSGGGAGAGGGSGSGAGTLTLTGNN 482
 
Name Accession Description Interval E-value
Nup96 pfam12110
Nuclear protein 96; Nup96 (often known by the name of its yeast homolog Nup145C) is part of ...
 1332-1623 4.79e-134

Nuclear protein 96; Nup96 (often known by the name of its yeast homolog Nup145C) is part of the Nup84 heptameric complex in the nuclear pore complex. Nup96 complexes with Sec13 in the middle of the heptamer. The function of the heptamer is to coat the curvature of the nuclear pore complex between the inner and outer nuclear membranes. Nup96 is predicted to be an alpha helical solenoid. The interaction between Nup96 and Sec13 is the point of curvature in the heptameric complex.


Pssm-ID: 463462  Cd Length: 287  Bit Score: 418.92  E-value: 4.79e-134
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102 1332 EAVFSYLTGKRISEACSLAQQSGDHRLALLLSQFVGSQSVRELLTMQLVDWHQLQADSFIQDERLRIFALLAGKPVWQLS 1411
Cdd:pfam12110    1 EKAFALLTGHRVEEACELAIDSGDFRLATLLSQAGGDDSFREDMAEQLDDWRESGVDSEIDEPRRKLYELLAGNVLVSEG 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102 1412 EKKQINVCSQLDWKRSLAIHLWYLLPPTASISRALSMYEEAFQntsdSDRYACSPLPSYLEGSGCVIAEEQNSQTPLrDV 1491
Cdd:pfam12110   81 KKSTINISEGLDWKRAFGLRLWYGIPPDTSIEDAVEAYEEALS----QGREPAPPLPWYLEEGDSESWEDPRLKKRE-DL 155

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102 1492 CFHLLKLYSDRHYDLNQLLEPRSITADPLDYRLSWHLWEVLRA--LNYTHLSAQCEGVLQASYAGQLESEGLWEWAIFVL 1569
Cdd:pfam12110  156 LYHLLKLYADPTAPLEAVLDPESSSPDPLDYRLSWHLYQVLSAvrLGYGHLSSAKADQLTLSFASQLESLGLWQWAVFVL 235

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1435761102 1570 LHIDNSGIREKAVRELLTRHCQLLETPESwaKETFLTQKLRVPAKWIHEAKAVR 1623
Cdd:pfam12110  236 LHLEDPARRERAVRELLARHAELISEDDA--KERFLTEKLKIPEAWIHEAKALY 287
Nucleoporin2 pfam04096
Nucleoporin autopeptidase; The nuclear pore complex protein plays a role in bidirectional ...
 738-880 2.62e-63

Nucleoporin autopeptidase; The nuclear pore complex protein plays a role in bidirectional transport across the nucleoporin complex in nucleocytoplasmic transport. The mammalian nuclear pore complex (NPC) is comprised of approximately 30 unique proteins, collectively known as nucleoporins. This family includes yeast family members such as Nup145p as well as vertebrate Nup98. The NUP C-terminal domains of Nup98 and Nup145 possess peptidase S59 autoproteolytic activity. The autoproteolytic sites of Nup98 and Nup145 each occur immediately C-terminal to the NUP C-terminal domain. Thus, although this domain occurs in the middle of each precursor polypeptide, it winds up at the C-terminal end of the N-terminal cleavage product. Cleavage of the peptide chains are necessary for the proper targeting to the nuclear pore.


Pssm-ID: 461171  Cd Length: 143  Bit Score: 211.97  E-value: 2.62e-63
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  738 KVGYYTIPSMDDLAKITnEKGECIVSDFTIGRKGYGSIYFEGDVNLTNLNLDDI----VHIRRKEVVVYLDDNQKPPVGE 813
Cdd:pfam04096    1 KGDYWTSPSLEELKKMS-REQLSSVENFTVGRKGYGSVRFLGPVDLTGLDLDEIfgkiVKFEPREVTVYPDESSKPPVGQ 79

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1435761102  814 GLNRKAEVTLDGVWPTDKTSRCLIKSPDRLADINYEGRLEavsRKQGAQFKEYRPETGSWVFKVSHF 880
Cdd:pfam04096   80 GLNVPATITLENVWPRDKDTKEPIKDPSGPRLEKHIERLK---RVQGTEFVSYDPETGTWTFKVEHF 143
COG4625 COG4625
Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function ...
 25-452 4.25e-16

Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function unknown];


Pssm-ID: 443664 [Multi-domain]  Cd Length: 900  Bit Score: 84.44  E-value: 4.25e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102   25 QNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSS 104
Cdd:COG4625     74 AGGGGGGGGGGGGGGGTGGVGGGGGGGGGGGGGGGGGGGGGGGGSAGGGGGGAGGAGGGGGGGAGGGGGGGGGGGAGGGG 153

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  105 QNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISt 184
Cdd:COG4625    154 GGGAGGAGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGNGGGGGGGGGGGGGGGGGGGGAGGGGGGGGGGGGGGGGGG- 232

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  185 khqcitamkeyeskSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQNKTAFGTSTT 264
Cdd:COG4625    233 --------------GGGGGGGGGGGGGGGAGGGGGGGGGNGGGGGAGGGGGGGGGGSGGGGGGGGGGGSGGGGGGGGGGG 298

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  265 GFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGqpstNTMGLFGVTQASQPGGLFGTATNTSTGTAFG 344
Cdd:COG4625    299 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGAGGGGGSGGA----GAGGGGAGGGGAGGGGGGGTGGGGGGGGGGG 374

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  345 TGTGLFGQTNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNFGFGTNTSGNSIFGSKP 424
Cdd:COG4625    375 GGSGGGGAGGGGGSGGGGGGGAGGGGGGGGAGGTGGGGAGGGGGAAGGGGGGTGAGGGGGGGGTGAGGGGATGGGGGGGG 454

                          410       420
                   ....*....|....*....|....*...
gi 1435761102  425 APGTLGTGLGAGFGTALGAGQASLFGNN 452
Cdd:COG4625    455 GAGGSGGGAGAGGGSGSGAGTLTLTGNN 482
Nucleoporin_FG pfam13634
Nucleoporin FG repeat region; This family includes a number of FG repeats that are found in ...
 40-149 7.94e-14

Nucleoporin FG repeat region; This family includes a number of FG repeats that are found in nucleoporin proteins. This family includes the yeast nucleoporins Nup116, Nup100, Nup49, Nup57 and Nup 145.


Pssm-ID: 463941 [Multi-domain]  Cd Length: 90  Bit Score: 68.80  E-value: 7.94e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102   40 SAFGSSNNT-GGLFGNSQTKP---GGLFGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTslfssqnnafaqnkpt 115
Cdd:pfam13634    1 GLFGAATSTsGGLFGNTSTTAasgGGLFGAASTATATTSGGGLFGNSSSNAPSGGLFGATNTTT---------------- 64

                           90       100       110
                   ....*....|....*....|....*....|....
gi 1435761102  116 gfgnfgTSTSSGGLFGTTNTTSNPfgSTSGSLFG 149
Cdd:pfam13634   65 ------QTATGGGLFGNNAATTTS--TTGGGLFG 90
ser_rich_anae_1 NF033849
serine-rich protein; This serine-rich protein belongs to a family with large size (over 1000 ...
 25-334 5.70e-10

serine-rich protein; This serine-rich protein belongs to a family with large size (over 1000 amino acids), which a highly serine-rich central region that averages over 300 aa in length. Species encoding members of this family of proteins tend to be anaerobic bacteria, including Gram-positive bacteria of the human gut microbiome and Chloroflexi from marine sediments.


Pssm-ID: 468206 [Multi-domain]  Cd Length: 1122  Bit Score: 64.64  E-value: 5.70e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102   25 QNTGFGTTSGGAFGTS-AFGSSNNTGGLFGNSQTKPGGL---FGTSSFSQPATSTSTGFGFGTSTGTantlfgtaSTGTS 100
Cdd:NF033849   255 QSHSVGTSESHSVGTSqSQSHTTGHGSTRGWSHTQSTSEsesTGQSSSVGTSESQSHGTTEGTSTTD--------SSSHS 326

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  101 LFSSQNNAFAQnkptgfgNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVST 180
Cdd:NF033849   327 QSSSYNVSSGT-------GVSSSHSDGTSQSTSISHSESSSESTGTSVGHSTSSSVSSSESSSRSSSSGVSGGFSGGIAG 399

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  181 NISTKHQCITAMKEYESKSLEelrlEDYQANRKGPQNQVGAGTTTglfGSSPATSSATGLFSSSTTNSGFAYGQNKTAfg 260
Cdd:NF033849   400 GGVTSEGLGASQGGSEGWGSG----DSVQSVSQSYGSSSSTGTSS---GHSDSSSHSTSSGQADSVSQGTSWSEGTGT-- 470

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1435761102  261 TSTTGFGTNPGglFGQQNQQTTSlFSKPFGQATTT-QNTGFSFGNTSTIGQPSTNTMGlfgvtQASQPGGLFGTA 334
Cdd:NF033849   471 SQGQSVGTSES--WSTSQSETDS-VGDSTGTSESVsQGDGRSTGRSESQGTSLGTSGG-----RTSGAGGSMGLG 537
auto_AIDA-I NF033176
autotransporter adhesin AIDA-I;
33-389 4.04e-05

autotransporter adhesin AIDA-I;


Pssm-ID: 380183 [Multi-domain]  Cd Length: 1287  Bit Score: 48.89  E-value: 4.04e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102   33 SGGAFGTSAFGSSNNTGGLFGNSQTK-PGGLFGTSSFSQPATS--TSTGFGFGT---STGTANTLFGTASTGTSLFSSQN 106
Cdd:NF033176   139 SGGAQNIYNLGHASNTVIFNGGNQTIfSGGISDDTNISSGGQQrvSSGGVASNTtinSSGTQNILSGGSTVSTHISSGGN 218

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  107 N-----AFAQNKPTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAaptGTTIKFNPPTGTDTMVKAGVSTN 181
Cdd:NF033176   219 QyisagGNASATVVSSGGFQRVSSGGTATGTVLSGGTQNVSSGGSAISTSVYSS---GVQTVYAGATVTDTTVNSGGKQN 295

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  182 ISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQ--NQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGfayGQNKTAF 259
Cdd:NF033176   296 ISSGGIVSGTIVNSSGTQNIYSGGSALSANIKGSQivNSDGTAINTLVNDGGYQHIRNGGVASGTIINQS---GRVNISS 372

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  260 GTSTTGFGTNPGGlfgqqnqqTTSLFSKPFGQATTTQNTGFSfgNTSTiGQPSTNTMGLFGVTQASQPGGlfgTATNTST 339
Cdd:NF033176   373 GGYAESTIINSGG--------TQSVLSGGYASGTLINNSGRE--NVSN-GGSAYNTIINAGGNQYIYSNG---EASGTTV 438

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|
gi 1435761102  340 GTAFgtgtglFGQTNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFgttSGG 389
Cdd:NF033176   439 NTSG------FQRVNSGGTATGTKLSGGNQNVSSGGKAIAAEVY---SGG 479
34 PHA02584
long tail fiber, proximal subunit; Provisional
 25-175 2.39e-03

long tail fiber, proximal subunit; Provisional


Pssm-ID: 222890 [Multi-domain]  Cd Length: 1229  Bit Score: 42.82  E-value: 2.39e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102   25 QNTGFGTTSGGAFGTSAFGSSNNTGG---------------------------LFGNSQTKPGGlfGTSSFSQPATSTST 77
Cdd:PHA02584   944 QNTSNGTVVVVDETSIAFYSQNNTTGnivfnidgtvdpinvnangtlnatgvaTNGRAVYAEGG--GIARTNNAARAITG 1021

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102   78 GFGFGTSTGTANTLFGTASTGTSLFSSQ-----NNAFAQNK--PTGFGNFGTSTSSGGLfgttnTTSNPFGSTSGSlfgp 150
Cdd:PHA02584  1022 GFTIRNDGSTTVFLLTAAGDQTGGFNGLksliiNNANGQVTinDNYIINAGGTIMSGGL-----TVNSRIRSQGTK---- 1092

                          170       180
                   ....*....|....*....|....*
gi 1435761102  151 SSFTAAPTGTTIKFNPPTGTDTMVK 175
Cdd:PHA02584  1093 ASYTRAPTADTVGFWSVDINDSATY 1117
dermokine cd21118
dermokine; Dermokine, also known as epidermis-specific secreted protein SK30/SK89, is a ...
 25-152 4.03e-03

dermokine; Dermokine, also known as epidermis-specific secreted protein SK30/SK89, is a skin-specific glycoprotein that may play a regulatory role in the crosstalk between barrier dysfunction and inflammation, and therefore play a role in inflammatory diseases such as psoriasis. Dermokine is one of the most highly expressed proteins in differentiating keratinocytes, found mainly in the spinous and granular layers of the epidermis, but also in the epithelia of the small intestine, macrophages of the lung, and endothelial cells of the lung. Mouse dermokine has been reported to be encoded by 22 exons, and its expression leads to alpha, beta, and gamma transcripts.


Pssm-ID: 411053 [Multi-domain]  Cd Length: 495  Bit Score: 41.91  E-value: 4.03e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102   25 QNTGFGTTSGGAFGTSAFGSSNNTGGLFG------NSQ--------------------TKPGGLFGTSSFSQPATSTSTG 78
Cdd:cd21118    145 GGTGGPWASGGNYGTNSLGGSVGQGGNGGplnygtNSQgavaqpgygtvrgnnqnsgcTNPPPSGSHESFSNSGGSSSSG 224

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1435761102   79 FGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNK-PTGFGNFGTSTSSGGLFG-TTNTTSNPFGSTSGSLFGPSS 152
Cdd:cd21118    225 SSGSQGSHGSNGQGSSGSSGGQGNGGNNGSSSSNSgNSGGSNGGSSGNSGSGSGgSSSGGSNGWGGSSSSGGSGGS 300
 
Name Accession Description Interval E-value
Nup96 pfam12110
Nuclear protein 96; Nup96 (often known by the name of its yeast homolog Nup145C) is part of ...
 1332-1623 4.79e-134

Nuclear protein 96; Nup96 (often known by the name of its yeast homolog Nup145C) is part of the Nup84 heptameric complex in the nuclear pore complex. Nup96 complexes with Sec13 in the middle of the heptamer. The function of the heptamer is to coat the curvature of the nuclear pore complex between the inner and outer nuclear membranes. Nup96 is predicted to be an alpha helical solenoid. The interaction between Nup96 and Sec13 is the point of curvature in the heptameric complex.


Pssm-ID: 463462  Cd Length: 287  Bit Score: 418.92  E-value: 4.79e-134
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102 1332 EAVFSYLTGKRISEACSLAQQSGDHRLALLLSQFVGSQSVRELLTMQLVDWHQLQADSFIQDERLRIFALLAGKPVWQLS 1411
Cdd:pfam12110    1 EKAFALLTGHRVEEACELAIDSGDFRLATLLSQAGGDDSFREDMAEQLDDWRESGVDSEIDEPRRKLYELLAGNVLVSEG 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102 1412 EKKQINVCSQLDWKRSLAIHLWYLLPPTASISRALSMYEEAFQntsdSDRYACSPLPSYLEGSGCVIAEEQNSQTPLrDV 1491
Cdd:pfam12110   81 KKSTINISEGLDWKRAFGLRLWYGIPPDTSIEDAVEAYEEALS----QGREPAPPLPWYLEEGDSESWEDPRLKKRE-DL 155

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102 1492 CFHLLKLYSDRHYDLNQLLEPRSITADPLDYRLSWHLWEVLRA--LNYTHLSAQCEGVLQASYAGQLESEGLWEWAIFVL 1569
Cdd:pfam12110  156 LYHLLKLYADPTAPLEAVLDPESSSPDPLDYRLSWHLYQVLSAvrLGYGHLSSAKADQLTLSFASQLESLGLWQWAVFVL 235

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1435761102 1570 LHIDNSGIREKAVRELLTRHCQLLETPESwaKETFLTQKLRVPAKWIHEAKAVR 1623
Cdd:pfam12110  236 LHLEDPARRERAVRELLARHAELISEDDA--KERFLTEKLKIPEAWIHEAKALY 287
Nucleoporin2 pfam04096
Nucleoporin autopeptidase; The nuclear pore complex protein plays a role in bidirectional ...
 738-880 2.62e-63

Nucleoporin autopeptidase; The nuclear pore complex protein plays a role in bidirectional transport across the nucleoporin complex in nucleocytoplasmic transport. The mammalian nuclear pore complex (NPC) is comprised of approximately 30 unique proteins, collectively known as nucleoporins. This family includes yeast family members such as Nup145p as well as vertebrate Nup98. The NUP C-terminal domains of Nup98 and Nup145 possess peptidase S59 autoproteolytic activity. The autoproteolytic sites of Nup98 and Nup145 each occur immediately C-terminal to the NUP C-terminal domain. Thus, although this domain occurs in the middle of each precursor polypeptide, it winds up at the C-terminal end of the N-terminal cleavage product. Cleavage of the peptide chains are necessary for the proper targeting to the nuclear pore.


Pssm-ID: 461171  Cd Length: 143  Bit Score: 211.97  E-value: 2.62e-63
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  738 KVGYYTIPSMDDLAKITnEKGECIVSDFTIGRKGYGSIYFEGDVNLTNLNLDDI----VHIRRKEVVVYLDDNQKPPVGE 813
Cdd:pfam04096    1 KGDYWTSPSLEELKKMS-REQLSSVENFTVGRKGYGSVRFLGPVDLTGLDLDEIfgkiVKFEPREVTVYPDESSKPPVGQ 79

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1435761102  814 GLNRKAEVTLDGVWPTDKTSRCLIKSPDRLADINYEGRLEavsRKQGAQFKEYRPETGSWVFKVSHF 880
Cdd:pfam04096   80 GLNVPATITLENVWPRDKDTKEPIKDPSGPRLEKHIERLK---RVQGTEFVSYDPETGTWTFKVEHF 143
COG4625 COG4625
Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function ...
 25-452 4.25e-16

Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function unknown];


Pssm-ID: 443664 [Multi-domain]  Cd Length: 900  Bit Score: 84.44  E-value: 4.25e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102   25 QNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSS 104
Cdd:COG4625     74 AGGGGGGGGGGGGGGGTGGVGGGGGGGGGGGGGGGGGGGGGGGGSAGGGGGGAGGAGGGGGGGAGGGGGGGGGGGAGGGG 153

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  105 QNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISt 184
Cdd:COG4625    154 GGGAGGAGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGNGGGGGGGGGGGGGGGGGGGGAGGGGGGGGGGGGGGGGGG- 232

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  185 khqcitamkeyeskSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQNKTAFGTSTT 264
Cdd:COG4625    233 --------------GGGGGGGGGGGGGGGAGGGGGGGGGNGGGGGAGGGGGGGGGGSGGGGGGGGGGGSGGGGGGGGGGG 298

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  265 GFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGqpstNTMGLFGVTQASQPGGLFGTATNTSTGTAFG 344
Cdd:COG4625    299 GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGAGGGGGSGGA----GAGGGGAGGGGAGGGGGGGTGGGGGGGGGGG 374

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  345 TGTGLFGQTNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNFGFGTNTSGNSIFGSKP 424
Cdd:COG4625    375 GGSGGGGAGGGGGSGGGGGGGAGGGGGGGGAGGTGGGGAGGGGGAAGGGGGGTGAGGGGGGGGTGAGGGGATGGGGGGGG 454

                          410       420
                   ....*....|....*....|....*...
gi 1435761102  425 APGTLGTGLGAGFGTALGAGQASLFGNN 452
Cdd:COG4625    455 GAGGSGGGAGAGGGSGSGAGTLTLTGNN 482
FhaB COG3210
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ...
 24-480 5.55e-14

Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442443 [Multi-domain]  Cd Length: 1698  Bit Score: 77.88  E-value: 5.55e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102   24 GQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFS 103
Cdd:COG3210    825 TATTGLTGTGDTTSGAGGSNTTDTTTGTTSDGASGGGTAGANSGSLAATAASITVGSGGVATSTGTANAGTLTNLGTTTN 904

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  104 SQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNIS 183
Cdd:COG3210    905 AASGNGAVLATVTATGTGGGGLTGGNAAAGGTGAGNGTTALSGTQGNAGLSAASASDGAGDTGASSAAGSSAVGTSANSA 984

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  184 TKHQCIT-AMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQNKTAFGTS 262
Cdd:COG3210    985 GSTGGVIaATGILVAGNSGTTASTTGGSGAIVAGGNGVTGTTGTASATGTGTAATAGGQNGVGVNASGISGGNAAALTAS 1064

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  263 TTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTA 342
Cdd:COG3210   1065 GTAGTTGGTAASNGGGGTAQASGAGTTHTLGGITNGGATGTSGGTTTSTGGVTASKVGGTTTVGATGTSTASTEAAGAGT 1144

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  343 FGTGTGLFGQTNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNFGFGTNTSGNSIFGS 422
Cdd:COG3210   1145 LTGLVAVSAVAGGASSASAGDTTAVAAATTTTTGSAINGGADSAATEGTAGTDLKGGDSTGGSTTTIGTTNVTTTTTLTA 1224

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1435761102  423 KPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTATLGFG 480
Cdd:COG3210   1225 SDTGNTTATGGSSAGQTGSFVAAGSASGTGDATTGATAGAVSNGATSTVAGNAGATAT 1282
Nucleoporin_FG pfam13634
Nucleoporin FG repeat region; This family includes a number of FG repeats that are found in ...
 40-149 7.94e-14

Nucleoporin FG repeat region; This family includes a number of FG repeats that are found in nucleoporin proteins. This family includes the yeast nucleoporins Nup116, Nup100, Nup49, Nup57 and Nup 145.


Pssm-ID: 463941 [Multi-domain]  Cd Length: 90  Bit Score: 68.80  E-value: 7.94e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102   40 SAFGSSNNT-GGLFGNSQTKP---GGLFGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTslfssqnnafaqnkpt 115
Cdd:pfam13634    1 GLFGAATSTsGGLFGNTSTTAasgGGLFGAASTATATTSGGGLFGNSSSNAPSGGLFGATNTTT---------------- 64

                           90       100       110
                   ....*....|....*....|....*....|....
gi 1435761102  116 gfgnfgTSTSSGGLFGTTNTTSNPfgSTSGSLFG 149
Cdd:pfam13634   65 ------QTATGGGLFGNNAATTTS--TTGGGLFG 90
Nucleoporin_FG pfam13634
Nucleoporin FG repeat region; This family includes a number of FG repeats that are found in ...
 239-332 1.78e-13

Nucleoporin FG repeat region; This family includes a number of FG repeats that are found in nucleoporin proteins. This family includes the yeast nucleoporins Nup116, Nup100, Nup49, Nup57 and Nup 145.


Pssm-ID: 463941 [Multi-domain]  Cd Length: 90  Bit Score: 67.64  E-value: 1.78e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  239 GLFSSSTTNSGFAYGQNKTAFGTSTTGFGTNpgglfgqQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTiGQPSTNTMGL 318
Cdd:pfam13634    1 GLFGAATSTSGGLFGNTSTTAASGGGLFGAA-------STATATTSGGGLFGNSSSNAPSGGLFGATNT-TTQTATGGGL 72

                           90
                   ....*....|....*...
gi 1435761102  319 FGVTQASQP----GGLFG 332
Cdd:pfam13634   73 FGNNAATTTsttgGGLFG 90
FhaB COG3210
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ...
 25-481 6.84e-13

Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442443 [Multi-domain]  Cd Length: 1698  Bit Score: 74.42  E-value: 6.84e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102   25 QNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSS 104
Cdd:COG3210    264 GTGNAGNTTIGTTVTGTNATGSNTAGASSGDTTTNGTSSVTGAGGTGVLGGGTAAGITTTNTVGGNGDGNNTTANSGAGL 343

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  105 QNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNIST 184
Cdd:COG3210    344 VSGGTGGNNGTTGTGAGSGLTGTGNGGGLTTAGAGTVASTVGTATASTGNASSTTVLGSGSLATGNTGTTIAGNGGSANA 423

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  185 KHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQNKTAFGTSTT 264
Cdd:COG3210    424 GGFTTTGGVLGITGNGTVTGGTIGGLTGSGTTNGAGLSGNTDVSGTGTVTNSAGNTTSATTLAGGGIGTVTTNATISNNA 503

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  265 GFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFG 344
Cdd:COG3210    504 GGDANGIATGLTGITAGGGGGGNATSGGTGGDGTTLSGSGLTTTVSGGASGTTAASGSNTANTLGVLAATGGTSNATTAG 583

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  345 TGTGLFGQTNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNFGFGTNTSGNSIFGSKP 424
Cdd:COG3210    584 NSTSATGGTGTNSGGTVLSIGTGSAGATGTITLGAGTSGAGANATGGGAGLTGSAVGAALSGTGSGTTGTASANGSNTTG 663

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1435761102  425 APGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPL-GTGAFGAPGFNTTTATLGFGA 481
Cdd:COG3210    664 VNTAGGTGGGTTGTVTSGATGGTTGTTLNAATGGTLnNAGNTLTISTGSITVTGQIGA 721
Nucleoporin_FG2 pfam15967
Nucleoporin FG repeated region; Nucleoporin_FG2, or nucleoporin p58/p45, is a family of ...
 44-273 6.17e-12

Nucleoporin FG repeated region; Nucleoporin_FG2, or nucleoporin p58/p45, is a family of chordate nucleoporins. The proteins carry many repeats of the FG sequence motif.


Pssm-ID: 435043 [Multi-domain]  Cd Length: 586  Bit Score: 70.47  E-value: 6.17e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102   44 SSNNTGGLFGNSQTKPGGL-FGTSSFSQPatSTSTGFGFGTSTGTANtlfGTASTGTSLFSSQNNAFAQNKPTGFGnfgt 122
Cdd:pfam15967    2 SGFSFGGGPGSTATAGGGFsFGAAAASNP--GSTGGFSFGTLGAAPA---ATATTTTATLGLGGGLFGQKPATGFT---- 72

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  123 stssgglFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMkeyeskslee 202
Cdd:pfam15967   73 -------FGTPASSTAATGPTGLTLGTPAATTAASTGFSLGFNKPAASATPFSLPASSTSGGGLSLGSVL---------- 135

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1435761102  203 lrledyqanrKGPQNQVGAGTTTGLFGSSPATSSA--TGLFSSSTTNS-GFAYGQNktafgTSTTGFGTNPGGL 273
Cdd:pfam15967  136 ----------TSTAAQQGATGFTLNLGGTPATTTAvsTGLSLGSTLTSlGGSLFQN-----TNSTGLGQTTLGL 194
Nucleoporin_FG pfam13634
Nucleoporin FG repeat region; This family includes a number of FG repeats that are found in ...
 272-392 1.05e-11

Nucleoporin FG repeat region; This family includes a number of FG repeats that are found in nucleoporin proteins. This family includes the yeast nucleoporins Nup116, Nup100, Nup49, Nup57 and Nup 145.


Pssm-ID: 463941 [Multi-domain]  Cd Length: 90  Bit Score: 62.63  E-value: 1.05e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  272 GLFGQQNQQTTSLFSkpfGQATTTQNTGFSFGNTSTiGQPSTNTMGLFGVTQASQP-GGLFGTatntstgtafgtgtglf 350
Cdd:pfam13634    1 GLFGAATSTSGGLFG---NTSTTAASGGGLFGAAST-ATATTSGGGLFGNSSSNAPsGGLFGA----------------- 59

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|..
gi 1435761102  351 gQTNTGFGAVGSTLFGNNklttfgssttSAPSFGTTSGGLFG 392
Cdd:pfam13634   60 -TNTTTQTATGGGLFGNN----------AATTTSTTGGGLFG 90
FhaB COG3210
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ...
 26-509 1.51e-10

Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442443 [Multi-domain]  Cd Length: 1698  Bit Score: 66.71  E-value: 1.51e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102   26 NTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQ 105
Cdd:COG3210    625 ANATGGGAGLTGSAVGAALSGTGSGTTGTASANGSNTTGVNTAGGTGGGTTGTVTSGATGGTTGTTLNAATGGTLNNAGN 704

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  106 NNAFAQNKPTGFGNFGTSTSSGG--------LFGTTNTTSNPFGSTSGSLFGPSSFTAAP---TGTTIKFNPPTGTDTmV 174
Cdd:COG3210    705 TLTISTGSITVTGQIGALANANGdtvtfgnlGTGATLTLNAGVTITSGNAGTLSIGLTANttaSGTTLTLANANGNTS-A 783

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  175 KAGVSTNISTKHQCITAmkeyesksleelrleDYQANRKGPqNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQ 254
Cdd:COG3210    784 GATLDNAGAEISIDITA---------------DGTITAAGT-TAINVTGSGGTITINTATTGLTGTGDTTSGAGGSNTTD 847

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  255 NKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTA 334
Cdd:COG3210    848 TTTGTTSDGASGGGTAGANSGSLAATAASITVGSGGVATSTGTANAGTLTNLGTTTNAASGNGAVLATVTATGTGGGGLT 927

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  335 TNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNFGFGTNT 414
Cdd:COG3210    928 GGNAAAGGTGAGNGTTALSGTQGNAGLSAASASDGAGDTGASSAAGSSAVGTSANSAGSTGGVIAATGILVAGNSGTTAS 1007

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  415 SGNSIFGSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTATLGFGAPQAPVALTDPNAS 494
Cdd:COG3210   1008 TTGGSGAIVAGGNGVTGTTGTASATGTGTAATAGGQNGVGVNASGISGGNAAALTASGTAGTTGGTAASNGGGGTAQASG 1087

                          490
                   ....*....|....*
gi 1435761102  495 AAQQAVLQQHINSLT 509
Cdd:COG3210   1088 AGTTHTLGGITNGGA 1102
AidA COG3468
Autotransporter adhesin AidA [Cell wall/membrane/envelope biogenesis, Intracellular ...
 26-393 2.95e-10

Autotransporter adhesin AidA [Cell wall/membrane/envelope biogenesis, Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442691 [Multi-domain]  Cd Length: 846  Bit Score: 65.35  E-value: 2.95e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102   26 NTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQ 105
Cdd:COG3468     63 AGGGGGGAGSGGGLAGAGSGGTGGNSTGGGGGNSGTGGTGGGGGGGGSGNGGGGGGGGGGGGTGGGGGGGTGSAGGGGGG 142

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  106 NNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTK 185
Cdd:COG3468    143 GGGGTGVGGTGAAAAGGGTGSGGGGSGGGGGAGGGGGGGAGGSGGAGSTGSGAGGGGGGSGGGGGAAGTGGGGGGGGGAG 222

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  186 hqcitamkeyeSKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQNKTAFGTSTTG 265
Cdd:COG3468    223 -----------GATGGAGSGGNTGGGVGGGGGSAGGTGGGGLTGGGAAGTGGGGGGTGTGSGGGGGGGANGGGSGGGGGA 291

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  266 FGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGT 345
Cdd:COG3468    292 SGTGGGGTASTGGGGGGGGGNGGGGGGGSNAGGGSGGGGGGGGGGGGGGTTLNGAGSAGGGTGAALAGTGGSGSGGGGGG 371

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*...
gi 1435761102  346 GTGLFGQTNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGN 393
Cdd:COG3468    372 GSGGGGGAGGGGANTGSDGVGTGLTTGGTGNNGGGGVGGGGGGGLTLT 419
FhaB COG3210
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ...
 25-419 3.96e-10

Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442443 [Multi-domain]  Cd Length: 1698  Bit Score: 65.17  E-value: 3.96e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102   25 QNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSS 104
Cdd:COG3210    368 NGGGLTTAGAGTVASTVGTATASTGNASSTTVLGSGSLATGNTGTTIAGNGGSANAGGFTTTGGVLGITGNGTVTGGTIG 447

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  105 QNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNIST 184
Cdd:COG3210    448 GLTGSGTTNGAGLSGNTDVSGTGTVTNSAGNTTSATTLAGGGIGTVTTNATISNNAGGDANGIATGLTGITAGGGGGGNA 527

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  185 KhqcitamkeyesksleelrledyqanrkGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQNKTAFGTSTT 264
Cdd:COG3210    528 T----------------------------SGGTGGDGTTLSGSGLTTTVSGGASGTTAASGSNTANTLGVLAATGGTSNA 579

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  265 GFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNTmGLFGVTQASQPGGLFGTATNTSTGTAFG 344
Cdd:COG3210    580 TTAGNSTSATGGTGTNSGGTVLSIGTGSAGATGTITLGAGTSGAGANATGG-GAGLTGSAVGAALSGTGSGTTGTASANG 658

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1435761102  345 TGTGLFGQTNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGlfgNKPTLTLGTNTNTSNFGFGTNTSGNSI 419
Cdd:COG3210    659 SNTTGVNTAGGTGGGTTGTVTSGATGGTTGTTLNAATGGTLNNAG---NTLTISTGSITVTGQIGALANANGDTV 730
FhaB COG3210
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ...
 25-511 4.23e-10

Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442443 [Multi-domain]  Cd Length: 1698  Bit Score: 65.17  E-value: 4.23e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102   25 QNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSS 104
Cdd:COG3210    466 VSGTGTVTNSAGNTTSATTLAGGGIGTVTTNATISNNAGGDANGIATGLTGITAGGGGGGNATSGGTGGDGTTLSGSGLT 545

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  105 QNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNIST 184
Cdd:COG3210    546 TTVSGGASGTTAASGSNTANTLGVLAATGGTSNATTAGNSTSATGGTGTNSGGTVLSIGTGSAGATGTITLGAGTSGAGA 625

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  185 KHQCITAmkeyesksleelrledyqaNRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQNKTAFGTSTT 264
Cdd:COG3210    626 NATGGGA-------------------GLTGSAVGAALSGTGSGTTGTASANGSNTTGVNTAGGTGGGTTGTVTSGATGGT 686

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  265 GFGTNPGGLFGQQNQQTTSLF--------SKPFGQATTTQNTGFSFGNTSTIGQPSTNTmglfGVTQASqpgGLFGTATN 336
Cdd:COG3210    687 TGTTLNAATGGTLNNAGNTLTistgsitvTGQIGALANANGDTVTFGNLGTGATLTLNA----GVTITS---GNAGTLSI 759

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  337 TSTGTAFGTGTGLFGQTNTGFGAVGSTLF-------------------GNNKLTTFGSSTTSAPSFGTTSGGLFGNKPTL 397
Cdd:COG3210    760 GLTANTTASGTTLTLANANGNTSAGATLDnagaeisiditadgtitaaGTTAINVTGSGGTITINTATTGLTGTGDTTSG 839

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  398 TLGTNTNTSNFGFGTNTSGNSIFGSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTATL 477
Cdd:COG3210    840 AGGSNTTDTTTGTTSDGASGGGTAGANSGSLAATAASITVGSGGVATSTGTANAGTLTNLGTTTNAASGNGAVLATVTAT 919

                          490       500       510
                   ....*....|....*....|....*....|....
gi 1435761102  478 GFGAPQAPVALTDPNASAAQQAVLQQHINSLTYS 511
Cdd:COG3210    920 GTGGGGLTGGNAAAGGTGAGNGTTALSGTQGNAG 953
ser_rich_anae_1 NF033849
serine-rich protein; This serine-rich protein belongs to a family with large size (over 1000 ...
 25-334 5.70e-10

serine-rich protein; This serine-rich protein belongs to a family with large size (over 1000 amino acids), which a highly serine-rich central region that averages over 300 aa in length. Species encoding members of this family of proteins tend to be anaerobic bacteria, including Gram-positive bacteria of the human gut microbiome and Chloroflexi from marine sediments.


Pssm-ID: 468206 [Multi-domain]  Cd Length: 1122  Bit Score: 64.64  E-value: 5.70e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102   25 QNTGFGTTSGGAFGTS-AFGSSNNTGGLFGNSQTKPGGL---FGTSSFSQPATSTSTGFGFGTSTGTantlfgtaSTGTS 100
Cdd:NF033849   255 QSHSVGTSESHSVGTSqSQSHTTGHGSTRGWSHTQSTSEsesTGQSSSVGTSESQSHGTTEGTSTTD--------SSSHS 326

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  101 LFSSQNNAFAQnkptgfgNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVST 180
Cdd:NF033849   327 QSSSYNVSSGT-------GVSSSHSDGTSQSTSISHSESSSESTGTSVGHSTSSSVSSSESSSRSSSSGVSGGFSGGIAG 399

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  181 NISTKHQCITAMKEYESKSLEelrlEDYQANRKGPQNQVGAGTTTglfGSSPATSSATGLFSSSTTNSGFAYGQNKTAfg 260
Cdd:NF033849   400 GGVTSEGLGASQGGSEGWGSG----DSVQSVSQSYGSSSSTGTSS---GHSDSSSHSTSSGQADSVSQGTSWSEGTGT-- 470

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1435761102  261 TSTTGFGTNPGglFGQQNQQTTSlFSKPFGQATTT-QNTGFSFGNTSTIGQPSTNTMGlfgvtQASQPGGLFGTA 334
Cdd:NF033849   471 SQGQSVGTSES--WSTSQSETDS-VGDSTGTSESVsQGDGRSTGRSESQGTSLGTSGG-----RTSGAGGSMGLG 537
Nucleoporin_FG pfam13634
Nucleoporin FG repeat region; This family includes a number of FG repeats that are found in ...
 25-93 2.33e-08

Nucleoporin FG repeat region; This family includes a number of FG repeats that are found in nucleoporin proteins. This family includes the yeast nucleoporins Nup116, Nup100, Nup49, Nup57 and Nup 145.


Pssm-ID: 463941 [Multi-domain]  Cd Length: 90  Bit Score: 53.00  E-value: 2.33e-08
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1435761102   25 QNTGFGTTSGGAFGTSAFGSSNNTGG-LFGNSQTKP--GGLFGTSSFSQPATSTSTGFGFGTSTGTANT---LFG 93
Cdd:pfam13634   16 NTSTTAASGGGLFGAASTATATTSGGgLFGNSSSNApsGGLFGATNTTTQTATGGGLFGNNAATTTSTTgggLFG 90
COG4625 COG4625
Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function ...
 26-390 2.56e-08

Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function unknown];


Pssm-ID: 443664 [Multi-domain]  Cd Length: 900  Bit Score: 59.02  E-value: 2.56e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102   26 NTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQ 105
Cdd:COG4625    173 GGGGGGGGGGGGGGGGGGGGNGGGGGGGGGGGGGGGGGGGGAGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGAGGGG 252

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  106 NNAFAQNkpTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTk 185
Cdd:COG4625    253 GGGGGNG--GGGGAGGGGGGGGGGSGGGGGGGGGGGSGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG- 329

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  186 hqcitamkeyesksleelrledYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQNKTAFGTSTTG 265
Cdd:COG4625    330 ----------------------GGGGAGGGGGSGGAGAGGGGAGGGGAGGGGGGGTGGGGGGGGGGGGGSGGGGAGGGGG 387

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  266 FGTNPGGLFGQQNQQTTSLFSKPFGQATTT-----QNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTA-TNTST 339
Cdd:COG4625    388 SGGGGGGGAGGGGGGGGAGGTGGGGAGGGGgaaggGGGGTGAGGGGGGGGTGAGGGGATGGGGGGGGGAGGSGGgAGAGG 467

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1435761102  340 GTAFGTGTGLFGQTNTGFGAVGSTLFGNNkltTFGSSTTSAPSFGTTSGGL 390
Cdd:COG4625    468 GSGSGAGTLTLTGNNTYTGTTTVNGGGNY---TQSAGSTLAVEVDAANSDR 515
Hia COG5295
Autotransporter adhesin [Intracellular trafficking, secretion, and vesicular transport, ...
 26-419 3.14e-08

Autotransporter adhesin [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444098 [Multi-domain]  Cd Length: 785  Bit Score: 58.63  E-value: 3.14e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102   26 NTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLfGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQ 105
Cdd:COG5295    178 SASGSSSGASGAAAASAATGASAGGTASAAASASSSA-TGTSASVGVNAGAATGSAASAGGSASAGAASGNATTASASSV 256

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  106 NNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTK 185
Cdd:COG5295    257 SGSAVAAGTASTATTASTTAASGAAGTATAAAGGDAAAAGSASSTGAANATAGGGNAGSGGGGAAALGSAGGSSGVGTAS 336

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  186 HQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQNKTAFGTSTTG 265
Cdd:COG5295    337 GASAAAATNDGTANGAGTSAAADATSGGGAGGGGAAATSSSGGSATAAGNAAGAAGAGSAGSGGSSTGASAGGGASAAGG 416

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  266 FGTNPGGLFGQQNQQTTSLFSKPFGQAT-----TTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTG 340
Cdd:COG5295    417 AAAGSAAAGTSSNTSAVGASNGASGTSSsassaGAAGGGTAGAGGAANVGAATTAASAAATAAAATSSAAIAGATATGAG 496

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1435761102  341 TAFGtgtglfGQTNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNFGFGTNTSGNSI 419
Cdd:COG5295    497 AAAG------GAGAGAAGGAGSAAAGGAANAAAASGATATAGSAGGGAAAAAGGGSTTAATGTNSVAVGNNTATGANSV 569
Hia COG5295
Autotransporter adhesin [Intracellular trafficking, secretion, and vesicular transport, ...
 26-457 6.74e-08

Autotransporter adhesin [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444098 [Multi-domain]  Cd Length: 785  Bit Score: 57.86  E-value: 6.74e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102   26 NTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQ 105
Cdd:COG5295    219 ASVGVNAGAATGSAASAGGSASAGAASGNATTASASSVSGSAVAAGTASTATTASTTAASGAAGTATAAAGGDAAAAGSA 298

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  106 NNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVK---AGVSTNI 182
Cdd:COG5295    299 SSTGAANATAGGGNAGSGGGGAAALGSAGGSSGVGTASGASAAAATNDGTANGAGTSAAADATSGGGAGGggaAATSSSG 378

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  183 STKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLF--SSSTTNSGFAYGQNKTAFG 260
Cdd:COG5295    379 GSATAAGNAAGAAGAGSAGSGGSSTGASAGGGASAAGGAAAGSAAAGTSSNTSAVGASNgaSGTSSSASSAGAAGGGTAG 458

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  261 TSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTG 340
Cdd:COG5295    459 AGGAANVGAATTAASAAATAAAATSSAAIAGATATGAGAAAGGAGAGAAGGAGSAAAGGAANAAAASGATATAGSAGGGA 538

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  341 TAFGTGTGLFGQTNTGFGAVGSTLFGNNKLTTFGSSTTsAPSFGTTSGGLFGNKPTLTLGTNTNTSNFGFGTNTSGNSIF 420
Cdd:COG5295    539 AAAAGGGSTTAATGTNSVAVGNNTATGANSVALGAGSV-ASGANSVSVGAAGAENVAAGATDTDAVNGGGAVATGDNSVA 617

                          410       420       430
                   ....*....|....*....|....*....|....*..
gi 1435761102  421 GSKPApgtlgtGLGAGFGTALGAGqASLFGNNQPKIG 457
Cdd:COG5295    618 VGNNA------QASGANSVALGAG-ATATANNSVALG 647
Nucleoporin_FG pfam13634
Nucleoporin FG repeat region; This family includes a number of FG repeats that are found in ...
 90-161 7.58e-08

Nucleoporin FG repeat region; This family includes a number of FG repeats that are found in nucleoporin proteins. This family includes the yeast nucleoporins Nup116, Nup100, Nup49, Nup57 and Nup 145.


Pssm-ID: 463941 [Multi-domain]  Cd Length: 90  Bit Score: 51.46  E-value: 7.58e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102   90 TLFGTA-STGTSLFSSQNNAF------------AQNKPTGFGNFG---TSTSSGGLFGTTNTTSNPfgSTSGSLFGPSSF 153
Cdd:pfam13634    1 GLFGAAtSTSGGLFGNTSTTAasggglfgaastATATTSGGGLFGnssSNAPSGGLFGATNTTTQT--ATGGGLFGNNAA 78


                   ....*...
gi 1435761102  154 TAAPTGTT 161
Cdd:pfam13634   79 TTTSTTGG 86
Nucleoporin_FG2 pfam15967
Nucleoporin FG repeated region; Nucleoporin_FG2, or nucleoporin p58/p45, is a family of ...
 28-182 2.06e-06

Nucleoporin FG repeated region; Nucleoporin_FG2, or nucleoporin p58/p45, is a family of chordate nucleoporins. The proteins carry many repeats of the FG sequence motif.


Pssm-ID: 435043 [Multi-domain]  Cd Length: 586  Bit Score: 52.75  E-value: 2.06e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102   28 GFGTTSGG--AFGTSAFGSSNNTGGL-FGNSQTKP--------------GGLFGtssfSQPATststGFGFGT------S 84
Cdd:pfam15967   11 GSTATAGGgfSFGAAAASNPGSTGGFsFGTLGAAPaatattttatlglgGGLFG----QKPAT----GFTFGTpasstaA 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102   85 TGTANTLFGTASTGTSlfSSQNNAFAQNKPTG----FGNFGTSTSSGGL-FGTTNTTSNPFGSTSGSLFG----PSSFTA 155
Cdd:pfam15967   83 TGPTGLTLGTPAATTA--ASTGFSLGFNKPAAsatpFSLPASSTSGGGLsLGSVLTSTAAQQGATGFTLNlggtPATTTA 160

                          170       180
                   ....*....|....*....|....*..
gi 1435761102  156 APTGTTIKFNPPTGTDTMVKAGVSTNI 182
Cdd:pfam15967  161 VSTGLSLGSTLTSLGGSLFQNTNSTGL 187
PPE COG5651
PPE-repeat protein [Function unknown];
31-183 2.48e-06

PPE-repeat protein [Function unknown];


Pssm-ID: 444372 [Multi-domain]  Cd Length: 385  Bit Score: 51.82  E-value: 2.48e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102   31 TTSGGAFGTSAFGSSNN-------TGGLFGNSQTKPGGL-FGTSSFSQPATSTSTGFgFGTSTGTANTLFGTASTGTSLF 102
Cdd:COG5651    175 TNPGGLLGAQNAGSGNTssnpgfaNLGLTGLNQVGIGGLnSGSGPIGLNSGPGNTGF-AGTGAAAGAAAAAAAAAAAAGA 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  103 SSQNN-----AFAQNKPTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAG 177
Cdd:COG5651    254 GASAAlaslaATLLNASSLGLAATAASSAATNLGLAGSPLGLAGGGAGAAAATGLGLGAGGAAGAAGATGAGAALGAGAA 333


                   ....*.
gi 1435761102  178 VSTNIS 183
Cdd:COG5651    334 AAAAGA 339
Nucleoporin_FG pfam13634
Nucleoporin FG repeat region; This family includes a number of FG repeats that are found in ...
 216-320 3.10e-06

Nucleoporin FG repeat region; This family includes a number of FG repeats that are found in nucleoporin proteins. This family includes the yeast nucleoporins Nup116, Nup100, Nup49, Nup57 and Nup 145.


Pssm-ID: 463941 [Multi-domain]  Cd Length: 90  Bit Score: 47.23  E-value: 3.10e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  216 QNQVGAGTTTGLFGSSPATSSATGLFSSsttnsgfaygqnktaFGTSTTgfGTNPGGLFGQQNQQttslfskpfgqaTTT 295
Cdd:pfam13634   16 NTSTTAASGGGLFGAASTATATTSGGGL---------------FGNSSS--NAPSGGLFGATNTT------------TQT 66

                           90       100
                   ....*....|....*....|....*
gi 1435761102  296 QNTGFSFGNTSTIGQPSTNTmGLFG 320
Cdd:pfam13634   67 ATGGGLFGNNAATTTSTTGG-GLFG 90
Nucleoporin_FG pfam13634
Nucleoporin FG repeat region; This family includes a number of FG repeats that are found in ...
 363-480 3.48e-06

Nucleoporin FG repeat region; This family includes a number of FG repeats that are found in nucleoporin proteins. This family includes the yeast nucleoporins Nup116, Nup100, Nup49, Nup57 and Nup 145.


Pssm-ID: 463941 [Multi-domain]  Cd Length: 90  Bit Score: 46.84  E-value: 3.48e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  363 TLFGNNKLTT---FGSSTTSApsfgTTSGGLFGNkptltlgtntntsNFGFGTNTSGNSIFGSKPAPgtlgtglgagfgt 439
Cdd:pfam13634    1 GLFGAATSTSgglFGNTSTTA----ASGGGLFGA-------------ASTATATTSGGGLFGNSSSN------------- 50

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|...
gi 1435761102  440 algAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTATLG--FG 480
Cdd:pfam13634   51 ---APSGGLFGATNTTTQTATGGGLFGNNAATTTSTTGGglFG 90
Nucleoporin_FG pfam13634
Nucleoporin FG repeat region; This family includes a number of FG repeats that are found in ...
 115-275 1.22e-05

Nucleoporin FG repeat region; This family includes a number of FG repeats that are found in nucleoporin proteins. This family includes the yeast nucleoporins Nup116, Nup100, Nup49, Nup57 and Nup 145.


Pssm-ID: 463941 [Multi-domain]  Cd Length: 90  Bit Score: 45.30  E-value: 1.22e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  115 TGFGNfgTSTSSGGLFGTTNTTsnpfGSTSGSLFGPSSFTAAPTgttikfnpptgtdtmvkagvstnistkhqcitamke 194
Cdd:pfam13634    1 GLFGA--ATSTSGGLFGNTSTT----AASGGGLFGAASTATATT------------------------------------ 38

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  195 yesksleelrledyqanrkgpqnqvgagTTTGLFGSSPATSSATGLFSSSTTNSGFAygQNKTAFG-TSTTGFGTNPGGL 273
Cdd:pfam13634   39 ----------------------------SGGGLFGNSSSNAPSGGLFGATNTTTQTA--TGGGLFGnNAATTTSTTGGGL 88


                   ..
gi 1435761102  274 FG 275
Cdd:pfam13634   89 FG 90
Nucleoporin_FG2 pfam15967
Nucleoporin FG repeated region; Nucleoporin_FG2, or nucleoporin p58/p45, is a family of ...
 228-482 2.44e-05

Nucleoporin FG repeated region; Nucleoporin_FG2, or nucleoporin p58/p45, is a family of chordate nucleoporins. The proteins carry many repeats of the FG sequence motif.


Pssm-ID: 435043 [Multi-domain]  Cd Length: 586  Bit Score: 49.28  E-value: 2.44e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  228 FGSSPATSSATGlfsssttnSGFAYGQNKTAFGTSTTG--FGTNPGGLFGQQNQQTTS--LFSKPFGQATTtqnTGFSFG 303
Cdd:pfam15967    6 FGGGPGSTATAG--------GGFSFGAAAASNPGSTGGfsFGTLGAAPAATATTTTATlgLGGGLFGQKPA---TGFTFG 74

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  304 NTSTigqpstntmglfgVTQASQPGGLFGTATNTSTGtafgtgtglfgqTNTGFGavgstlFGNNKLTtfGSSTT-SAPS 382
Cdd:pfam15967   75 TPAS-------------STAATGPTGLTLGTPAATTA------------ASTGFS------LGFNKPA--ASATPfSLPA 121

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  383 FGTTSGGLFGNKPTLTLGTNTNTSNFGFGtntsgnsiFGSKPAPGTLGTGLGAGFGTALGAGqASLFGNNQPKiggPLGT 462
Cdd:pfam15967  122 SSTSGGGLSLGSVLTSTAAQQGATGFTLN--------LGGTPATTTAVSTGLSLGSTLTSLG-GSLFQNTNST---GLGQ 189

                          250       260
                   ....*....|....*....|
gi 1435761102  463 GAFGAPGFNTTTATLGFGAP 482
Cdd:pfam15967  190 TTLGLTLLATSTAPVSAPAA 209
Chi1 COG3469
Chitinase [Carbohydrate transport and metabolism];
26-172 3.67e-05

Chitinase [Carbohydrate transport and metabolism];


Pssm-ID: 442692 [Multi-domain]  Cd Length: 534  Bit Score: 48.60  E-value: 3.67e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102   26 NTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTGFGFGTST----------GTANTLFGTA 95
Cdd:COG3469     52 AASGSAGSGTGTTAASSTAATSSTTSTTATATAAAAAATSTSATLVATSTASGANTGTSTvtttstgagsVTSTTSSTAG 131

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1435761102   96 STGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGlfgTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDT 172
Cdd:COG3469    132 STTTSGASATSSAGSTTTTTTVSGTETATGGTT---TTSTTTTTTSASTTPSATTTATATTASGATTPSATTTATTT 205
auto_AIDA-I NF033176
autotransporter adhesin AIDA-I;
33-389 4.04e-05

autotransporter adhesin AIDA-I;


Pssm-ID: 380183 [Multi-domain]  Cd Length: 1287  Bit Score: 48.89  E-value: 4.04e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102   33 SGGAFGTSAFGSSNNTGGLFGNSQTK-PGGLFGTSSFSQPATS--TSTGFGFGT---STGTANTLFGTASTGTSLFSSQN 106
Cdd:NF033176   139 SGGAQNIYNLGHASNTVIFNGGNQTIfSGGISDDTNISSGGQQrvSSGGVASNTtinSSGTQNILSGGSTVSTHISSGGN 218

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  107 N-----AFAQNKPTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAaptGTTIKFNPPTGTDTMVKAGVSTN 181
Cdd:NF033176   219 QyisagGNASATVVSSGGFQRVSSGGTATGTVLSGGTQNVSSGGSAISTSVYSS---GVQTVYAGATVTDTTVNSGGKQN 295

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  182 ISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQ--NQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGfayGQNKTAF 259
Cdd:NF033176   296 ISSGGIVSGTIVNSSGTQNIYSGGSALSANIKGSQivNSDGTAINTLVNDGGYQHIRNGGVASGTIINQS---GRVNISS 372

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  260 GTSTTGFGTNPGGlfgqqnqqTTSLFSKPFGQATTTQNTGFSfgNTSTiGQPSTNTMGLFGVTQASQPGGlfgTATNTST 339
Cdd:NF033176   373 GGYAESTIINSGG--------TQSVLSGGYASGTLINNSGRE--NVSN-GGSAYNTIINAGGNQYIYSNG---EASGTTV 438

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|
gi 1435761102  340 GTAFgtgtglFGQTNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFgttSGG 389
Cdd:NF033176   439 NTSG------FQRVNSGGTATGTKLSGGNQNVSSGGKAIAAEVY---SGG 479
Chi1 COG3469
Chitinase [Carbohydrate transport and metabolism];
26-167 2.17e-04

Chitinase [Carbohydrate transport and metabolism];


Pssm-ID: 442692 [Multi-domain]  Cd Length: 534  Bit Score: 45.90  E-value: 2.17e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102   26 NTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQ 105
Cdd:COG3469     75 TTSTTATATAAAAAATSTSATLVATSTASGANTGTSTVTTTSTGAGSVTSTTSSTAGSTTTSGASATSSAGSTTTTTTVS 154

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1435761102  106 NNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSNpfgSTSGSLFGPSSFTAAPTGTTIKFNPP 167
Cdd:COG3469    155 GTETATGGTTTTSTTTTTTSASTTPSATTTATA---TTASGATTPSATTTATTTGPPTPGLP 213
NupH_GANP pfam16768
Nucleoporin homology of Germinal-centre associated nuclear protein; NupH_GANP is the ...
 25-311 4.60e-04

Nucleoporin homology of Germinal-centre associated nuclear protein; NupH_GANP is the nucleoporin-homology domain at the N-terminus of human GANP or germinal-centre associated nuclear proteins. GANP is part of the TREX-2 complex that links transcription with nuclear messenger RNA export, and it associates with the mRNP particle through the interaction of the NupH_GANP with NXF1, the export factor. This attachment mediates efficient delivery of mRNPs to nuclear pore complexes.


Pssm-ID: 435572 [Multi-domain]  Cd Length: 292  Bit Score: 44.13  E-value: 4.60e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102   25 QNTGFGTTSGGAFGTsafgssnntgglfgnSQTKPGGLFGTSS-FSQPATSTSTGFGFGTSTGtantlFGTASTGTSLFS 103
Cdd:pfam16768   10 QPSAFSTSSSPSTGT---------------FQAKPPFRFGQPSlFGQNNTLSGKNSGFSQVSS-----FPTTSGVSHSSS 69

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  104 SQNNAFAQnkptgfgnfgtsTSSGGLFGTTNTTSnPFGSTSgslfGPSSfTAAPTGTTIKFNPPTGTdtmvkaGVSTNIS 183
Cdd:pfam16768   70 GQTLGFTQ------------TSGVGLFSGLEHTP-SFVATS----GPSS-SSVPSNPGFSFKSPTNL------GAFPSTS 125

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  184 TKHQCITAMK-------EYESKSLEELRLEDYQANRKGP---QNQVGAGTTTglFgSSPATSSATGLF--------SSST 245
Cdd:pfam16768  126 TFGPESGEVAssgfgktEFSFKPPENAVFRPIFGAESEPektQSQITSGFFT--F-SHPVSSGPGGLApfsfsqvtSSSA 202

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1435761102  246 TNSGFAYGQNKTAFGTSTTGFGTNPGglfgqQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQP 311
Cdd:pfam16768  203 TSSNFTFSKPVSSNNSSSAFAPALSS-----QNVEEEKRGPKSFFGSSNSSFTSFPNSSSGSLGEP 263
COG4625 COG4625
Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function ...
 26-177 4.66e-04

Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function unknown];


Pssm-ID: 443664 [Multi-domain]  Cd Length: 900  Bit Score: 45.15  E-value: 4.66e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102   26 NTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQ 105
Cdd:COG4625    369 GGGGGGGGSGGGGAGGGGGSGGGGGGGAGGGGGGGGAGGTGGGGAGGGGGAAGGGGGGTGAGGGGGGGGTGAGGGGATGG 448

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1435761102  106 NNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAG 177
Cdd:COG4625    449 GGGGGGGAGGSGGGAGAGGGSGSGAGTLTLTGNNTYTGTTTVNGGGNYTQSAGSTLAVEVDAANSDRLVVTG 520
Chi1 COG3469
Chitinase [Carbohydrate transport and metabolism];
214-395 1.42e-03

Chitinase [Carbohydrate transport and metabolism];


Pssm-ID: 442692 [Multi-domain]  Cd Length: 534  Bit Score: 43.20  E-value: 1.42e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  214 GPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQ-TTSLFSKPFGQA 292
Cdd:COG3469     29 AASVTLTAATATTVVSTTGSVVVAASGSAGSGTGTTAASSTAATSSTTSTTATATAAAAAATSTSATlVATSTASGANTG 108

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  293 TTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLTT 372
Cdd:COG3469    109 TSTVTTTSTGAGSVTSTTSSTAGSTTTSGASATSSAGSTTTTTTVSGTETATGGTTTTSTTTTTTSASTTPSATTTATAT 188

                          170       180
                   ....*....|....*....|....*
gi 1435761102  373 --FGSSTTSAPSFGTTSGGLFGNKP 395
Cdd:COG3469    189 taSGATTPSATTTATTTGPPTPGLP 213
34 PHA02584
long tail fiber, proximal subunit; Provisional
 25-175 2.39e-03

long tail fiber, proximal subunit; Provisional


Pssm-ID: 222890 [Multi-domain]  Cd Length: 1229  Bit Score: 42.82  E-value: 2.39e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102   25 QNTGFGTTSGGAFGTSAFGSSNNTGG---------------------------LFGNSQTKPGGlfGTSSFSQPATSTST 77
Cdd:PHA02584   944 QNTSNGTVVVVDETSIAFYSQNNTTGnivfnidgtvdpinvnangtlnatgvaTNGRAVYAEGG--GIARTNNAARAITG 1021

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102   78 GFGFGTSTGTANTLFGTASTGTSLFSSQ-----NNAFAQNK--PTGFGNFGTSTSSGGLfgttnTTSNPFGSTSGSlfgp 150
Cdd:PHA02584  1022 GFTIRNDGSTTVFLLTAAGDQTGGFNGLksliiNNANGQVTinDNYIINAGGTIMSGGL-----TVNSRIRSQGTK---- 1092

                          170       180
                   ....*....|....*....|....*
gi 1435761102  151 SSFTAAPTGTTIKFNPPTGTDTMVK 175
Cdd:PHA02584  1093 ASYTRAPTADTVGFWSVDINDSATY 1117
dermokine cd21118
dermokine; Dermokine, also known as epidermis-specific secreted protein SK30/SK89, is a ...
 25-152 4.03e-03

dermokine; Dermokine, also known as epidermis-specific secreted protein SK30/SK89, is a skin-specific glycoprotein that may play a regulatory role in the crosstalk between barrier dysfunction and inflammation, and therefore play a role in inflammatory diseases such as psoriasis. Dermokine is one of the most highly expressed proteins in differentiating keratinocytes, found mainly in the spinous and granular layers of the epidermis, but also in the epithelia of the small intestine, macrophages of the lung, and endothelial cells of the lung. Mouse dermokine has been reported to be encoded by 22 exons, and its expression leads to alpha, beta, and gamma transcripts.


Pssm-ID: 411053 [Multi-domain]  Cd Length: 495  Bit Score: 41.91  E-value: 4.03e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102   25 QNTGFGTTSGGAFGTSAFGSSNNTGGLFG------NSQ--------------------TKPGGLFGTSSFSQPATSTSTG 78
Cdd:cd21118    145 GGTGGPWASGGNYGTNSLGGSVGQGGNGGplnygtNSQgavaqpgygtvrgnnqnsgcTNPPPSGSHESFSNSGGSSSSG 224

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1435761102   79 FGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNK-PTGFGNFGTSTSSGGLFG-TTNTTSNPFGSTSGSLFGPSS 152
Cdd:cd21118    225 SSGSQGSHGSNGQGSSGSSGGQGNGGNNGSSSSNSgNSGGSNGGSSGNSGSGSGgSSSGGSNGWGGSSSSGGSGGS 300
PTZ00473 PTZ00473
Plasmodium Vir superfamily; Provisional
 26-100 4.55e-03

Plasmodium Vir superfamily; Provisional


Pssm-ID: 240430 [Multi-domain]  Cd Length: 420  Bit Score: 41.37  E-value: 4.55e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102   26 NTGFGTTSGGAF--------------GTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTGFGFGTSTGTANTl 91
Cdd:PTZ00473   315 RGPYNANYGGQFnsrsgrtgssesirGFTYDSSTTYGGSSYGTSQTDSTSTYGSRSTFDSSTGGGSQSGGGSTYGGSST- 393


                   ....*....
gi 1435761102   92 FGTASTGTS 100
Cdd:PTZ00473   394 FDGSSRGSS 402
Nucleoporin_FG2 pfam15967
Nucleoporin FG repeated region; Nucleoporin_FG2, or nucleoporin p58/p45, is a family of ...
 226-392 6.88e-03

Nucleoporin FG repeated region; Nucleoporin_FG2, or nucleoporin p58/p45, is a family of chordate nucleoporins. The proteins carry many repeats of the FG sequence motif.


Pssm-ID: 435043 [Multi-domain]  Cd Length: 586  Bit Score: 41.19  E-value: 6.88e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  226 GLFGSSPATSSATGLFSSSTTNSGFA--YGQNKTAFGTSTTGFGtnpgglFGqqnqqttslFSKPFGQAT-------TTQ 296
Cdd:pfam15967   61 GLFGQKPATGFTFGTPASSTAATGPTglTLGTPAATTAASTGFS------LG---------FNKPAASATpfslpasSTS 125

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  297 NTGFSFGNTSTIGQPSTNTMGlFGVTQASQPgglfgtATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLTTFGSS 376
Cdd:pfam15967  126 GGGLSLGSVLTSTAAQQGATG-FTLNLGGTP------ATTTAVSTGLSLGSTLTSLGGSLFQNTNSTGLGQTTLGLTLLA 198

                          170
                   ....*....|....*..
gi 1435761102  377 TTSAPSFGTTSG-GLFG 392
Cdd:pfam15967  199 TSTAPVSAPAASeGLGG 215
PPE COG5651
PPE-repeat protein [Function unknown];
26-159 7.43e-03

PPE-repeat protein [Function unknown];


Pssm-ID: 444372 [Multi-domain]  Cd Length: 385  Bit Score: 40.65  E-value: 7.43e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102   26 NTGFGTTSGGAFGTSAFGSSNN-TGGLFGNSQTKPGGLFGTS---SFSQPATSTSTGFGFGTST---------GTANTLF 92
Cdd:COG5651    194 NPGFANLGLTGLNQVGIGGLNSgSGPIGLNSGPGNTGFAGTGaaaGAAAAAAAAAAAAGAGASAalaslaatlLNASSLG 273

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1435761102   93 GTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTG 159
Cdd:COG5651    274 LAATAASSAATNLGLAGSPLGLAGGGAGAAAATGLGLGAGGAAGAAGATGAGAALGAGAAAAAAGAA 340
PPE COG5651
PPE-repeat protein [Function unknown];
233-444 9.63e-03

PPE-repeat protein [Function unknown];


Pssm-ID: 444372 [Multi-domain]  Cd Length: 385  Bit Score: 40.26  E-value: 9.63e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  233 ATSSATGL--FSS---STTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFS--KPFGQATTTQNTGF---SF 302
Cdd:COG5651    157 ASAAAVALtpFTQpppTITNPGGLLGAQNAGSGNTSSNPGFANLGLTGLNQVGIGGLNSgsGPIGLNSGPGNTGFagtGA 236

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1435761102  303 GNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLTTFGSSTTSAPS 382
Cdd:COG5651    237 AAGAAAAAAAAAAAAGAGASAALASLAATLLNASSLGLAATAASSAATNLGLAGSPLGLAGGGAGAAAATGLGLGAGGAA 316

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1435761102  383 FGTTSGGLFGNKPTLTLGTNTNTSNFGFGTNTSGNSIFGSKPAPGTLGTGLGAGFGTALGAG 444
Cdd:COG5651    317 GAAGATGAGAALGAGAAAAAAGAAAGAGAAAAAAAGGAGGGGGGALGAGGGGGSAGAAAGAA 378
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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