|
Name |
Accession |
Description |
Interval |
E-value |
| MCM9 |
cd17760 |
DNA helicase Mcm9; Mcm9 plays an important role homologous recombination repair. It forms a ... |
307-605 |
0e+00 |
|
DNA helicase Mcm9; Mcm9 plays an important role homologous recombination repair. It forms a complex with Mcm8 that is required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350666 [Multi-domain] Cd Length: 299 Bit Score: 605.69 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 307 EILASLCPQVFGLYLVKLAVAMVLAGGVQRIDATGTRIRGESHLLLVGDPGTGKSQFLKYAVKITPRSVLTAGIGSTSAG 386
Cdd:cd17760 1 EILASLCPQVFGLYNVKLAVAMVLAGGVQRIDASGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTAGIGSTSAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 387 LTVTAVKDFGEWNLEAGALVLADGGLCCIDEFNSIKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPKGHYD 466
Cdd:cd17760 81 LTVTAVKDGGEWNLEAGALVLADGGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPKGQYD 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 467 PAESVSVNIALGSPLLSRFDLVLVLLDTKNEEWDRIISSFILQNKGCPSKSEKLWSMEKMKTYFCLIKRIQPKLSDESNL 546
Cdd:cd17760 161 PNESISVNIALASPLLSRFDLVLVLLDTKNEDWDRIISSFILENKGEPSKSSKLWSMEKMRTYFCLIKNLRPVLSDEANA 240
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 2163339433 547 ILVRYYQMQRQSDCRNAARTTIRLLESLIRLAEAHARLMFRDTVTLEDAVTVVSVMESS 605
Cdd:cd17760 241 ILLRYYQLQRQSDCRNAARTTIRMLESLIRLAEAHARLMFRETVTEEDAITVVSVMESS 299
|
|
| Mcm2 |
COG1241 |
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and ... |
13-607 |
6.29e-149 |
|
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and repair];
Pssm-ID: 440854 [Multi-domain] Cd Length: 682 Bit Score: 463.12 E-value: 6.29e-149
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 13 QVFESYllqHHRDDILGILRQGDDEAHYPVLVDALTLFetNMEIGEYFNAFPSQVLPIFDGALRRAamavlqaaTPSPEL 92
Cdd:COG1241 11 EFLRRY---KYRDEILELAQEYPEKRSLVVDYNDLYSF--DPDLADDLLENPDEVLEAAEEALREI--------DLEPYD 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 93 RMKPNLHARISGLPICPELtrEHIPkTRDVGHFLSVTGTVIRTSLVKVLEFERSYICNKCKHVFVAKADFEQYYafcRPS 172
Cdd:COG1241 78 VSLGDAHVRITNLPETVPI--RDIR-SDHIGKLISVEGIVRKATEVKPKITEAAFECPRCGTETYVPQTGEKLQ---EPH 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 173 AClneEGCN-STKFTCLSGTSSSpsscRDYQEIKIQEQVQRLSVGSIPRCMVVVLEDDLVDSCKSGDDITVYGVVMQRWK 251
Cdd:COG1241 152 EC---PGCGrQGPFKLLPEKSEF----IDAQKIRIQEPPEDLPGGQQPQSIDVILEDDLVGEVRPGDRVTVTGILRIEQR 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 252 PFHQDARCDLELVLKANYVKVNNEQLAGVTIDEEVRKEFEDfwekhrnnpLAGRNEIL----ASLCPQVFGLYLVKLAVA 327
Cdd:COG1241 225 TSGRGKSTIFDLYLEANSIEVEEKEFEEIEITEEDEEKIKE---------LSKDPDIYekiiASIAPSIYGYEEIKEAIA 295
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 328 MVLAGGVQRIDATGTRIRGESHLLLVGDPGTGKSQFLKYAVKITPRSVLTAGIGSTSAGLTVTAVKD---FGEWNLEAGA 404
Cdd:COG1241 296 LQLFGGVPKVLPDGSRIRGDIHILLVGDPGTAKSQLLRYAARLAPRGVYTSGKGSTAAGLTAAAVRDdfgTGRWTLEAGA 375
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 405 LVLADGGLCCIDEFNSIKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPK-GHYDPAESVSVNIALGSPLLS 483
Cdd:COG1241 376 LVLADGGLACIDELDKMREEDRSALHEAMEQQTISIAKAGIVATLNARCSVLAAANPKyGRFDPYEPIAEQIDLPPTLLS 455
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 484 RFDLVLVLLDTKNEEWDRIISSFILQN--KGCPSKSEKLWSMEK---------MKTYFCLIKR-IQPKLSDESNLILVRY 551
Cdd:COG1241 456 RFDLIFVLRDKPDEERDRELARHILKVhrAGELLEQEIEEETEEvkpeidpdlLRKYIAYARRnVFPVLTEEAKDLIEDF 535
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*...
gi 2163339433 552 Y-QMQRQSDCRNAART-TIRLLESLIRLAEAHARLMFRDTVTLEDAVTVVSVMESSMQ 607
Cdd:COG1241 536 YvDMRKKGEDEDSPVPiTARQLEALIRLAEASARMRLSDTVTEEDAERAIRLVDSCLK 593
|
|
| minchrom_main_MCM |
NF040949 |
minichromosome maintenance protein MCM; |
42-607 |
2.65e-141 |
|
minichromosome maintenance protein MCM;
Pssm-ID: 468880 [Multi-domain] Cd Length: 681 Bit Score: 442.83 E-value: 2.65e-141
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 42 VLVDALTLFETNMEIGEYFNAFPSQVLPIFDGALRRAAmavlqaATPSPEL-RMKPNLHARISGLPicpeltrEHIP--- 117
Cdd:NF040949 36 LVVDFNDLYMFDPELADLLIEKPDEVLPAASKALKEIV------EEEDPEYaEEVAKFHVRFRNLP-------RTVPlrd 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 118 -KTRDVGHFLSVTGTVIRTSLVKVLEFERSYICNKCKHVFVAKADFEQYYAFC-RPSACLNeegCNST-KFTCLSGTSSS 194
Cdd:NF040949 103 lRSEYIGKLIAVEGIVTRTTPVKPRIVKAVFRCRDCGCEFEWPEEEEESYEIVePPTVCPV---CGKPgSFRLLQEKSKF 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 195 PsscrDYQEIKIQEQVQRLSVGSIPRCMVVVLEDDLVDSCKSGDDITVYGVV-MQRWKPFHQDARCDLELVLKANYVKVN 273
Cdd:NF040949 180 I----DWQKIVVQERPEELPPGQLPRSIEVVLEDDLVDTARPGDRVTVTGILrIKPDSSLKKGSRPIFKNYIEANHIEVS 255
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 274 NEQLAGVTIDEEVRKEFEDfwekhrnnpLAG----RNEILASLCPQVFGLYLVKLAVAMVLAGGVQRIDATGTRIRGESH 349
Cdd:NF040949 256 QKELEEVEITEEDEEKILE---------LAKdpwiREKIIASIAPSIYGHWEIKEAIALLLFGGVPKVLPDGTRIRGDIH 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 350 LLLVGDPGTGKSQFLKYAVKITPRSVLTAGIGSTSAGLTVTAVKD--FGEWNLEAGALVLADGGLCCIDEFNSIKEHDRT 427
Cdd:NF040949 327 VLIVGDPGTAKSQLLQYVARLAPRAVYTSGKGSTAAGLTAAVVRDklTGEYYLEAGALVLADGGVAVIDEIDKMREEDRS 406
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 428 SIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPK-GHYDPAESVSVNIALGSPLLSRFDLVLVLLDTKNEEWDRIISSF 506
Cdd:NF040949 407 AIHEAMEQQTVSIAKAGIVATLNARASVLAAGNPKfGRYDPNRSVAENIDLPPTILSRFDLIFVIRDKPNEERDRRLARH 486
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 507 ILQNKGCPSKSEKLWSMEKMKTYFCLIKR-IQPKLSDESNLILVRYY-QMQRQSDCRNAART----TIRLLESLIRLAEA 580
Cdd:NF040949 487 ILDVHSGKEKVKPEIDPDLLKKYIAYARKyVRPKLTEEAKKLIEDFYvEMRKSSKSSEDPDSpipiTARQLEALIRLSEA 566
|
570 580
....*....|....*....|....*..
gi 2163339433 581 HARLMFRDTVTLEDAVTVVSVMESSMQ 607
Cdd:NF040949 567 HAKMRLKDEVTAEDAERAIRLMLAFLE 593
|
|
| MCM |
smart00350 |
minichromosome maintenance proteins; |
110-605 |
9.56e-134 |
|
minichromosome maintenance proteins;
Pssm-ID: 214631 [Multi-domain] Cd Length: 509 Bit Score: 416.66 E-value: 9.56e-134
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 110 ELTREHIpktrdvGHFLSVTGTVIRTSLVKVLEFERSYICNKCKHVfvaKADFEQYYAFCRPSACLNEEGCNSTKFTCLS 189
Cdd:smart00350 7 ELRADHL------GKLVRISGIVTRTSGVRPKLKRASFTCEKCGAT---LGPEIQSGRETEPTVCPPRECQSPTPFSLNH 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 190 GTSSspssCRDYQEIKIQEQVQRLSVGSIPRCMVVVLEDDLVDSCKSGDDITVYGVVmqRWKPFH-----QDARCDLELV 264
Cdd:smart00350 78 ERST----FIDFQKIKLQESPEEVPVGQLPRSVDVILDGDLVDKAKPGDRVEVTGIY--RNVPYGfklntVKGLPVFATY 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 265 LKANYVKVNN--------EQLAGVTIDEEVR--KEF---EDFWEKhrnnplagrneILASLCPQVFGLYLVKLAVAMVLA 331
Cdd:smart00350 152 IEANHVRKLDykrsfedsSFSVQSLSDEEEEeiRKLskdPDIYER-----------LARSLAPSIYGHEDIKKAILLLLF 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 332 GGVQRIDATGTRIRGESHLLLVGDPGTGKSQFLKYAVKITPRSVLTAGIGSTSAGLTVTAVKD--FGEWNLEAGALVLAD 409
Cdd:smart00350 221 GGVHKNLPDGMKIRGDINILLCGDPGTAKSQLLKYVEKTAPRAVYTTGKGSSAVGLTAAVTRDpeTREFTLEAGALVLAD 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 410 GGLCCIDEFNSIKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNP-KGHYDPAESVSVNIALGSPLLSRFDLV 488
Cdd:smart00350 301 NGVCCIDEFDKMDDSDRTAIHEAMEQQTISIAKAGITTTLNARCSVLAAANPiGGRYDPKLTPEENIDLPAPILSRFDLL 380
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 489 LVLLDTKNEEWDRIISSFIL----QNKGCP-SKSEKLWSMEKMKTYFCLIK-RIQPKLSDESNLILVRYY----QMQRQS 558
Cdd:smart00350 381 FVVLDEVDEERDRELAKHVVdlhrYSHPEEdEAFEPPLSQEKLRKYIAYAReKIKPKLSEEAADKLVKAYvdlrKEDSQT 460
|
490 500 510 520
....*....|....*....|....*....|....*....|....*..
gi 2163339433 559 DCRNAARTTIRLLESLIRLAEAHARLMFRDTVTLEDAVTVVSVMESS 605
Cdd:smart00350 461 ESRSSIPITVRQLESIIRLSEAHAKMRLSDVVEEADVEEAIRLLRES 507
|
|
| MCM |
pfam00493 |
MCM P-loop domain; |
307-508 |
1.87e-98 |
|
MCM P-loop domain;
Pssm-ID: 459830 [Multi-domain] Cd Length: 224 Bit Score: 311.77 E-value: 1.87e-98
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 307 EILA-SLCPQVFGLYLVKLAVAMVLAGGVQRIDATGTRIRGESHLLLVGDPGTGKSQFLKYAVKITPRSVLTAGIGSTSA 385
Cdd:pfam00493 16 DKLAdSIAPSIYGHEDVKKAILLQLFGGVKKILPDGTRLRGDINVLLVGDPGTAKSQLLKYVEKIAPRAVYTSGKGSSAA 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 386 GLTVTAVKD--FGEWNLEAGALVLADGGLCCIDEFNSIKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPK- 462
Cdd:pfam00493 96 GLTAAVVRDpvTGEFVLEAGALVLADGGVCCIDEFDKMNDEDRVALHEAMEQQTISIAKAGIVATLNARCSILAAANPIf 175
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 2163339433 463 GHYDPAESVSVNIALGSPLLSRFDLVLVLLDTKNEEWDRIISSFIL 508
Cdd:pfam00493 176 GRYDPKKSIAENINLPPPLLSRFDLIFVLLDKPDEEKDERLAKHIV 221
|
|
| PTZ00111 |
PTZ00111 |
DNA replication licensing factor MCM4; Provisional |
226-605 |
4.23e-58 |
|
DNA replication licensing factor MCM4; Provisional
Pssm-ID: 173403 [Multi-domain] Cd Length: 915 Bit Score: 217.55 E-value: 4.23e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 226 LEDDLVDSCKSGDDITVYGVVmqRWKPFHQDARCDLELVLKANYVKVNNEQLAGVTIDEEVRKEFE------DFWE---- 295
Cdd:PTZ00111 352 LYDDLIDSVKTGDRVTVVGIL--KVTPIRTSTTRRTLKSLYTYFVNVIHVKVINSTNANQPEKGLKylgnenDFSDlqvy 429
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 296 ---KHRNNPLAGRnEILASLCPQVFGLYLVKLAVAMVLAGGVQRIDATGT---------RIRGESHLLLVGDPGTGKSQF 363
Cdd:PTZ00111 430 kilELSRNPMIYR-ILLDSFAPSIKARNNVKIGLLCQLFSGNKNSSDFNKspdacykvdNFRGIINVLLCGDPGTAKSQL 508
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 364 LKYAVKITPRSVLTAGIGSTSAGLTVTAV---KDFGEWNLEAGALVLADGGLCCIDEFNSIKEHDRTSIHEAMEQQTISV 440
Cdd:PTZ00111 509 LHYTHLLSPRSIYTSGKSSSSVGLTASIKfneSDNGRAMIQPGAVVLANGGVCCIDELDKCHNESRLSLYEVMEQQTVTI 588
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 441 AKAGLVCKLNTRTTILAATNP-KGHYDPAESVSVNIALGSPLLSRFDLVLVLLDTKNEEWDRIISSFILQNKGCPS---- 515
Cdd:PTZ00111 589 AKAGIVATLKAETAILASCNPiNSRYNKNKAVIENINISPSLFTRFDLIYLVLDHIDQDTDQLISLSIAKDFLLPHmtgs 668
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 516 --------------------KSEKLWSMEKMKTYFCLIK--RIQ--PKLSDESNLILVRYYQMQRQSD------------ 559
Cdd:PTZ00111 669 gndedtydrsntmhvedeslRSEKDYNKNDLDMLRMYIKfsKLHcfPKLSDEAKKVITREYVKMRQGNfqtsnldeleha 748
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*....
gi 2163339433 560 ----------CRNAART---TIRLLESLIRLAEAHARLMFRDTVTLEDAVTVVSVMESS 605
Cdd:PTZ00111 749 qedddddlyyQSSGTRMiyvSSRMISSIIRISVSLARMRLSTVVTPADALQAVQIVKSS 807
|
|
| MCM_OB |
pfam17207 |
MCM OB domain; This family contains an OB-fold found within MCM proteins. This domain contains ... |
118-245 |
3.16e-23 |
|
MCM OB domain; This family contains an OB-fold found within MCM proteins. This domain contains an insertion at the zinc binding motif.
Pssm-ID: 465381 [Multi-domain] Cd Length: 126 Bit Score: 96.01 E-value: 3.16e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 118 KTRDVGHFLSVTGTVIRTSLVKVLEFERSYICNKCKHVFVAKadfeqyyaFCRPSACLNEEgCNST-KFTCLSGTSSsps 196
Cdd:pfam17207 6 RSEHIGKLVSVSGIVTRTSEVRPKLKKATFTCRKCGHTVGVK--------ITEPTKCPNPE-CGNKdPFKLVHEKSK--- 73
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 2163339433 197 sCRDYQEIKIQEQVQRLSVGSIPRCMVVVLEDDLVDSCKSGDDITVYGV 245
Cdd:pfam17207 74 -FVDFQKIKIQESPEEVPAGELPRSLDVILDDDLVDRVKPGDRVTVTGI 121
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| MCM9 |
cd17760 |
DNA helicase Mcm9; Mcm9 plays an important role homologous recombination repair. It forms a ... |
307-605 |
0e+00 |
|
DNA helicase Mcm9; Mcm9 plays an important role homologous recombination repair. It forms a complex with Mcm8 that is required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350666 [Multi-domain] Cd Length: 299 Bit Score: 605.69 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 307 EILASLCPQVFGLYLVKLAVAMVLAGGVQRIDATGTRIRGESHLLLVGDPGTGKSQFLKYAVKITPRSVLTAGIGSTSAG 386
Cdd:cd17760 1 EILASLCPQVFGLYNVKLAVAMVLAGGVQRIDASGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTAGIGSTSAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 387 LTVTAVKDFGEWNLEAGALVLADGGLCCIDEFNSIKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPKGHYD 466
Cdd:cd17760 81 LTVTAVKDGGEWNLEAGALVLADGGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPKGQYD 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 467 PAESVSVNIALGSPLLSRFDLVLVLLDTKNEEWDRIISSFILQNKGCPSKSEKLWSMEKMKTYFCLIKRIQPKLSDESNL 546
Cdd:cd17760 161 PNESISVNIALASPLLSRFDLVLVLLDTKNEDWDRIISSFILENKGEPSKSSKLWSMEKMRTYFCLIKNLRPVLSDEANA 240
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 2163339433 547 ILVRYYQMQRQSDCRNAARTTIRLLESLIRLAEAHARLMFRDTVTLEDAVTVVSVMESS 605
Cdd:cd17760 241 ILLRYYQLQRQSDCRNAARTTIRMLESLIRLAEAHARLMFRETVTEEDAITVVSVMESS 299
|
|
| Mcm2 |
COG1241 |
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and ... |
13-607 |
6.29e-149 |
|
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and repair];
Pssm-ID: 440854 [Multi-domain] Cd Length: 682 Bit Score: 463.12 E-value: 6.29e-149
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 13 QVFESYllqHHRDDILGILRQGDDEAHYPVLVDALTLFetNMEIGEYFNAFPSQVLPIFDGALRRAamavlqaaTPSPEL 92
Cdd:COG1241 11 EFLRRY---KYRDEILELAQEYPEKRSLVVDYNDLYSF--DPDLADDLLENPDEVLEAAEEALREI--------DLEPYD 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 93 RMKPNLHARISGLPICPELtrEHIPkTRDVGHFLSVTGTVIRTSLVKVLEFERSYICNKCKHVFVAKADFEQYYafcRPS 172
Cdd:COG1241 78 VSLGDAHVRITNLPETVPI--RDIR-SDHIGKLISVEGIVRKATEVKPKITEAAFECPRCGTETYVPQTGEKLQ---EPH 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 173 AClneEGCN-STKFTCLSGTSSSpsscRDYQEIKIQEQVQRLSVGSIPRCMVVVLEDDLVDSCKSGDDITVYGVVMQRWK 251
Cdd:COG1241 152 EC---PGCGrQGPFKLLPEKSEF----IDAQKIRIQEPPEDLPGGQQPQSIDVILEDDLVGEVRPGDRVTVTGILRIEQR 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 252 PFHQDARCDLELVLKANYVKVNNEQLAGVTIDEEVRKEFEDfwekhrnnpLAGRNEIL----ASLCPQVFGLYLVKLAVA 327
Cdd:COG1241 225 TSGRGKSTIFDLYLEANSIEVEEKEFEEIEITEEDEEKIKE---------LSKDPDIYekiiASIAPSIYGYEEIKEAIA 295
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 328 MVLAGGVQRIDATGTRIRGESHLLLVGDPGTGKSQFLKYAVKITPRSVLTAGIGSTSAGLTVTAVKD---FGEWNLEAGA 404
Cdd:COG1241 296 LQLFGGVPKVLPDGSRIRGDIHILLVGDPGTAKSQLLRYAARLAPRGVYTSGKGSTAAGLTAAAVRDdfgTGRWTLEAGA 375
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 405 LVLADGGLCCIDEFNSIKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPK-GHYDPAESVSVNIALGSPLLS 483
Cdd:COG1241 376 LVLADGGLACIDELDKMREEDRSALHEAMEQQTISIAKAGIVATLNARCSVLAAANPKyGRFDPYEPIAEQIDLPPTLLS 455
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 484 RFDLVLVLLDTKNEEWDRIISSFILQN--KGCPSKSEKLWSMEK---------MKTYFCLIKR-IQPKLSDESNLILVRY 551
Cdd:COG1241 456 RFDLIFVLRDKPDEERDRELARHILKVhrAGELLEQEIEEETEEvkpeidpdlLRKYIAYARRnVFPVLTEEAKDLIEDF 535
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*...
gi 2163339433 552 Y-QMQRQSDCRNAART-TIRLLESLIRLAEAHARLMFRDTVTLEDAVTVVSVMESSMQ 607
Cdd:COG1241 536 YvDMRKKGEDEDSPVPiTARQLEALIRLAEASARMRLSDTVTEEDAERAIRLVDSCLK 593
|
|
| MCM |
cd17706 |
MCM helicase family; MCM helicases are a family of helicases that play an important role in ... |
307-605 |
2.66e-142 |
|
MCM helicase family; MCM helicases are a family of helicases that play an important role in replication and homologous recombination repair. The heterohexameric ring-shaped Mcm2-7 complex is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases. Mcm8 and Mcm9, form a complex required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350658 [Multi-domain] Cd Length: 311 Bit Score: 431.77 E-value: 2.66e-142
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 307 EILASLCPQVFGLYLVKLAVAMVLAGGVQRIDATGTRIRGESHLLLVGDPGTGKSQFLKYAVKITPRSVLTAGIGSTSAG 386
Cdd:cd17706 1 ILADSIAPSIYGHEDVKKAVLLQLFGGVQKILEDGTRIRGDIHILLVGDPGTAKSQILKYVLKIAPRGVYTSGKGSSGAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 387 LTVTAVKD--FGEWNLEAGALVLADGGLCCIDEFNSIKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPK-G 463
Cdd:cd17706 81 LTAAVVRDseTGEWYLEAGALVLADGGVCCIDEFDKMKELDRTALHEAMEQQTISIAKAGIVTTLNARCSILAAANPKgG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 464 HYDPAESVSVNIALGSPLLSRFDLVLVLLDTKNEEWDRIISSFILQNKGC--------PSKSEKLWSMEKMKTYFCLIKR 535
Cdd:cd17706 161 RYNPKLSPIENINLPSPLLSRFDLIFVIRDDPDEERDEELAEHIIDLHRGsdpeeqvkPEEDGIPIDIELLRKYILYARQ 240
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2163339433 536 IQPKLSDESNLILVRYYQMQRQSDCRN-AARTTIRLLESLIRLAEAHARLMFRDTVTLEDAVTVVSVMESS 605
Cdd:cd17706 241 IHPKISEEAREKLVRWYVELRKESERRsTIPITARQLESVIRLAEAHAKMRLSEVVTEEDVEEAIRLVRHS 311
|
|
| minchrom_main_MCM |
NF040949 |
minichromosome maintenance protein MCM; |
42-607 |
2.65e-141 |
|
minichromosome maintenance protein MCM;
Pssm-ID: 468880 [Multi-domain] Cd Length: 681 Bit Score: 442.83 E-value: 2.65e-141
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 42 VLVDALTLFETNMEIGEYFNAFPSQVLPIFDGALRRAAmavlqaATPSPEL-RMKPNLHARISGLPicpeltrEHIP--- 117
Cdd:NF040949 36 LVVDFNDLYMFDPELADLLIEKPDEVLPAASKALKEIV------EEEDPEYaEEVAKFHVRFRNLP-------RTVPlrd 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 118 -KTRDVGHFLSVTGTVIRTSLVKVLEFERSYICNKCKHVFVAKADFEQYYAFC-RPSACLNeegCNST-KFTCLSGTSSS 194
Cdd:NF040949 103 lRSEYIGKLIAVEGIVTRTTPVKPRIVKAVFRCRDCGCEFEWPEEEEESYEIVePPTVCPV---CGKPgSFRLLQEKSKF 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 195 PsscrDYQEIKIQEQVQRLSVGSIPRCMVVVLEDDLVDSCKSGDDITVYGVV-MQRWKPFHQDARCDLELVLKANYVKVN 273
Cdd:NF040949 180 I----DWQKIVVQERPEELPPGQLPRSIEVVLEDDLVDTARPGDRVTVTGILrIKPDSSLKKGSRPIFKNYIEANHIEVS 255
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 274 NEQLAGVTIDEEVRKEFEDfwekhrnnpLAG----RNEILASLCPQVFGLYLVKLAVAMVLAGGVQRIDATGTRIRGESH 349
Cdd:NF040949 256 QKELEEVEITEEDEEKILE---------LAKdpwiREKIIASIAPSIYGHWEIKEAIALLLFGGVPKVLPDGTRIRGDIH 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 350 LLLVGDPGTGKSQFLKYAVKITPRSVLTAGIGSTSAGLTVTAVKD--FGEWNLEAGALVLADGGLCCIDEFNSIKEHDRT 427
Cdd:NF040949 327 VLIVGDPGTAKSQLLQYVARLAPRAVYTSGKGSTAAGLTAAVVRDklTGEYYLEAGALVLADGGVAVIDEIDKMREEDRS 406
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 428 SIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPK-GHYDPAESVSVNIALGSPLLSRFDLVLVLLDTKNEEWDRIISSF 506
Cdd:NF040949 407 AIHEAMEQQTVSIAKAGIVATLNARASVLAAGNPKfGRYDPNRSVAENIDLPPTILSRFDLIFVIRDKPNEERDRRLARH 486
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 507 ILQNKGCPSKSEKLWSMEKMKTYFCLIKR-IQPKLSDESNLILVRYY-QMQRQSDCRNAART----TIRLLESLIRLAEA 580
Cdd:NF040949 487 ILDVHSGKEKVKPEIDPDLLKKYIAYARKyVRPKLTEEAKKLIEDFYvEMRKSSKSSEDPDSpipiTARQLEALIRLSEA 566
|
570 580
....*....|....*....|....*..
gi 2163339433 581 HARLMFRDTVTLEDAVTVVSVMESSMQ 607
Cdd:NF040949 567 HAKMRLKDEVTAEDAERAIRLMLAFLE 593
|
|
| MCM |
smart00350 |
minichromosome maintenance proteins; |
110-605 |
9.56e-134 |
|
minichromosome maintenance proteins;
Pssm-ID: 214631 [Multi-domain] Cd Length: 509 Bit Score: 416.66 E-value: 9.56e-134
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 110 ELTREHIpktrdvGHFLSVTGTVIRTSLVKVLEFERSYICNKCKHVfvaKADFEQYYAFCRPSACLNEEGCNSTKFTCLS 189
Cdd:smart00350 7 ELRADHL------GKLVRISGIVTRTSGVRPKLKRASFTCEKCGAT---LGPEIQSGRETEPTVCPPRECQSPTPFSLNH 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 190 GTSSspssCRDYQEIKIQEQVQRLSVGSIPRCMVVVLEDDLVDSCKSGDDITVYGVVmqRWKPFH-----QDARCDLELV 264
Cdd:smart00350 78 ERST----FIDFQKIKLQESPEEVPVGQLPRSVDVILDGDLVDKAKPGDRVEVTGIY--RNVPYGfklntVKGLPVFATY 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 265 LKANYVKVNN--------EQLAGVTIDEEVR--KEF---EDFWEKhrnnplagrneILASLCPQVFGLYLVKLAVAMVLA 331
Cdd:smart00350 152 IEANHVRKLDykrsfedsSFSVQSLSDEEEEeiRKLskdPDIYER-----------LARSLAPSIYGHEDIKKAILLLLF 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 332 GGVQRIDATGTRIRGESHLLLVGDPGTGKSQFLKYAVKITPRSVLTAGIGSTSAGLTVTAVKD--FGEWNLEAGALVLAD 409
Cdd:smart00350 221 GGVHKNLPDGMKIRGDINILLCGDPGTAKSQLLKYVEKTAPRAVYTTGKGSSAVGLTAAVTRDpeTREFTLEAGALVLAD 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 410 GGLCCIDEFNSIKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNP-KGHYDPAESVSVNIALGSPLLSRFDLV 488
Cdd:smart00350 301 NGVCCIDEFDKMDDSDRTAIHEAMEQQTISIAKAGITTTLNARCSVLAAANPiGGRYDPKLTPEENIDLPAPILSRFDLL 380
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 489 LVLLDTKNEEWDRIISSFIL----QNKGCP-SKSEKLWSMEKMKTYFCLIK-RIQPKLSDESNLILVRYY----QMQRQS 558
Cdd:smart00350 381 FVVLDEVDEERDRELAKHVVdlhrYSHPEEdEAFEPPLSQEKLRKYIAYAReKIKPKLSEEAADKLVKAYvdlrKEDSQT 460
|
490 500 510 520
....*....|....*....|....*....|....*....|....*..
gi 2163339433 559 DCRNAARTTIRLLESLIRLAEAHARLMFRDTVTLEDAVTVVSVMESS 605
Cdd:smart00350 461 ESRSSIPITVRQLESIIRLSEAHAKMRLSDVVEEADVEEAIRLLRES 507
|
|
| MCM6 |
cd17757 |
DNA replication licensing factor Mcm6; Mcm6 is a helicase that play an important role in ... |
308-605 |
3.05e-102 |
|
DNA replication licensing factor Mcm6; Mcm6 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350663 [Multi-domain] Cd Length: 307 Bit Score: 325.48 E-value: 3.05e-102
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 308 ILASLCPQVFGLYLVKLAVAMVLAGGVQRIDATGTRIRGESHLLLVGDPGTGKSQFLKYAVKITPRSVLTAGIGSTSAGL 387
Cdd:cd17757 2 LVRSIAPSIYGHEEVKKGILLMLLGGVHKITREGISLRGDINVCIVGDPSTAKSQFLKYVEEFSPRAVYTSGKASSAAGL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 388 TVTAVKD--FGEWNLEAGALVLADGGLCCIDEFNSIKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNP-KGH 464
Cdd:cd17757 82 TAAVVRDeeTGDFVIEAGALMLADNGICCIDEFDKMDIKDQVAIHEAMEQQTISITKAGIQATLNARTSILAAANPvGGR 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 465 YDPAESVSVNIALGSPLLSRFDLVLVLLDTKNEEWDRIISSFILQNKGCPSKS-EKLWSMEKMKTYFCLIKRIQPKLSDE 543
Cdd:cd17757 162 YDRSKSLKQNINISAPIMSRFDLFFVLLDECNEVTDYAIASHIVDLHSKREEAiEPPFTAEQLKRYIAYARTFKPKLTKE 241
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2163339433 544 SNLILVRYYQMQRQSDC----RNAARTTIRLLESLIRLAEAHARLMFRDTVTLEDAVTVVSVMESS 605
Cdd:cd17757 242 AKDELVEQYKELRQDDAsgstRSSYRITVRQLESLIRLSEAIARLHCSDEVTPEHVEEAARLLKKS 307
|
|
| MCM |
pfam00493 |
MCM P-loop domain; |
307-508 |
1.87e-98 |
|
MCM P-loop domain;
Pssm-ID: 459830 [Multi-domain] Cd Length: 224 Bit Score: 311.77 E-value: 1.87e-98
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 307 EILA-SLCPQVFGLYLVKLAVAMVLAGGVQRIDATGTRIRGESHLLLVGDPGTGKSQFLKYAVKITPRSVLTAGIGSTSA 385
Cdd:pfam00493 16 DKLAdSIAPSIYGHEDVKKAILLQLFGGVKKILPDGTRLRGDINVLLVGDPGTAKSQLLKYVEKIAPRAVYTSGKGSSAA 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 386 GLTVTAVKD--FGEWNLEAGALVLADGGLCCIDEFNSIKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPK- 462
Cdd:pfam00493 96 GLTAAVVRDpvTGEFVLEAGALVLADGGVCCIDEFDKMNDEDRVALHEAMEQQTISIAKAGIVATLNARCSILAAANPIf 175
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 2163339433 463 GHYDPAESVSVNIALGSPLLSRFDLVLVLLDTKNEEWDRIISSFIL 508
Cdd:pfam00493 176 GRYDPKKSIAENINLPPPLLSRFDLIFVLLDKPDEEKDERLAKHIV 221
|
|
| MCM_arch |
cd17761 |
archaeal MCM protein; archaeal MCM proteins form a homohexameric ring homologous to the ... |
308-605 |
4.32e-96 |
|
archaeal MCM protein; archaeal MCM proteins form a homohexameric ring homologous to the eukaryotic Mcm2-7 helicase and also function as the replicative helicase at the replication fork
Pssm-ID: 350667 [Multi-domain] Cd Length: 308 Bit Score: 309.00 E-value: 4.32e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 308 ILASLCPQVFGLYLVKLAVAMVLAGGVQRIDATGTRIRGESHLLLVGDPGTGKSQFLKYAVKITPRSVLTAGIGSTSAGL 387
Cdd:cd17761 3 IISSIAPSIYGHEDVKEAIALQLFGGVPKVLPDGTRIRGDIHILLVGDPGTAKSQLLKYVSKVAPRAVYTTGKGSTAAGL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 388 TVTAVKD--FGEWNLEAGALVLADGGLCCIDEFNSIKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPK-GH 464
Cdd:cd17761 83 TAAVVRDegTGEWYLEAGALVLADKGIAVVDEIDKMRKEDRSALHEAMEQQTISIAKAGIVATLNARAAVLAAANPKfGR 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 465 YDPAESVSVNIALGSPLLSRFDLVLVLLDTKNEEWDRIISSFILQ--NKGCPSKSEKLWSMEKMKTYFCLIKR-IQPKLS 541
Cdd:cd17761 163 FDSYRPVAEQIDLPPTLLSRFDLIFVLKDTPNEEKDRRLANHILDthSGGEMREIKPEIDPDLLRKYIAYARKnVRPVLT 242
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2163339433 542 DESNLILVRYYQMQRQS--DCRNAARTTIRLLESLIRLAEAHARLMFRDTVTLEDAVTVVSVMESS 605
Cdd:cd17761 243 EEAKQLIKDFYVEMRKSgqETPSPVPITARQLEALVRLSEASARMRLSQEVTLEDAERAIRIMLNC 308
|
|
| MCM2 |
cd17753 |
DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in ... |
308-605 |
1.83e-87 |
|
DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350659 [Multi-domain] Cd Length: 325 Bit Score: 285.88 E-value: 1.83e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 308 ILASLCPQVFGLYLVKLAVAMVLAGGVQRIDATGTRIRGESHLLLVGDPGTGKSQFLKYAVKITPRSVLTAGIGSTSAGL 387
Cdd:cd17753 2 IINSIAPSIYGHDDIKTAIALALFGGVAKNPGGKHRIRGDINVLLLGDPGTAKSQFLKYVEKTAHRAVFTTGQGASAVGL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 388 TVTAVKD--FGEWNLEAGALVLADGGLCCIDEFNSIKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPK-GH 464
Cdd:cd17753 82 TASVRKDpvTKEWTLEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCSVIAAANPIgGR 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 465 YDPAESVSVNIALGSPLLSRFDLVLVLLDTKNEEWDRIISSFILQN--KGCPSKSEKLWSMEK----------------- 525
Cdd:cd17753 162 YNPTLTFAQNVNLTEPILSRFDILCVVRDTVDPEEDERLAKFVVGShvRSHPENDEDREGEEEknqrqrpketkvepipq 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 526 --MKTYFCLIK-RIQPKLSD-ESNLILVRYYQMQRQSDCRNAARTTIRLLESLIRLAEAHARLMFRDTVTLEDAVTVVSV 601
Cdd:cd17753 242 elLRKYIHYAReKVRPKLNQmDMDKVSRVYADLRKESMATGSLPITVRHLESIIRISEAHAKMHLREYVSEEDVDMAIRV 321
|
....
gi 2163339433 602 MESS 605
Cdd:cd17753 322 MLDS 325
|
|
| MCM7 |
cd17758 |
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in ... |
310-605 |
9.40e-87 |
|
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350664 [Multi-domain] Cd Length: 306 Bit Score: 283.15 E-value: 9.40e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 310 ASLCPQVFGLYLVKLAVAMVLAGGVQrIDATGTRIRGESHLLLVGDPGTGKSQFLKYAVKITPRSVLTAGIGSTSAGLTV 389
Cdd:cd17758 4 ASIAPEIYGHEDVKKALLLLLVGGVD-KRGDGMKIRGDINICLMGDPGVAKSQLLKYICRIAPRSVYTTGRGSSGVGLTA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 390 TAVKD--FGEWNLEAGALVLADGGLCCIDEFNSIKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPK-GHYD 466
Cdd:cd17758 83 AVMKDpvTGEMTLEGGALVLADQGICCIDEFDKMDESDRTAIHEVMEQQTISIAKAGITTTLNARTSILAAANPAyGRYN 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 467 PAESVSVNIALGSPLLSRFDLVLVLLDTKNEEWDRIISSFIL----QNKGCPSKSEKLwSMEKMKTYFCLIKRIQPKLSD 542
Cdd:cd17758 163 PRRSPEQNINLPAALLSRFDLLFLILDKPDRDNDLRLAEHVTyvhqHNKQPDSDFEPL-DPKLLRAYIALAKRKRPTVPP 241
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2163339433 543 E-SNLILVRYYQMQRQSDCRN-AARTTIRLLESLIRLAEAHARLMFRDTVTLEDAVTVVSVMESS 605
Cdd:cd17758 242 AlADYIVQAYVEMRQEAKRSKdFTFTTPRTLLAILRLSQALARLRLSDSVEIDDVEEALRLMEMS 306
|
|
| MCM4 |
cd17755 |
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in ... |
308-605 |
2.60e-85 |
|
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350661 [Multi-domain] Cd Length: 309 Bit Score: 279.32 E-value: 2.60e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 308 ILA-SLCPQVFGLYLVKLAVAMVLAGGVQRIDAT-GTRIRGESHLLLVGDPGTGKSQFLKYAVKITPRSVLTAGIGSTSA 385
Cdd:cd17755 1 RLArSIAPSIYELEDVKKGILLQLFGGTRKDFTKtGGKYRGDINILLCGDPGTSKSQLLQYVHKISPRGVYTSGKGSSAV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 386 GLTVTAVKD--FGEWNLEAGALVLADGGLCCIDEFNSIKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPKG 463
Cdd:cd17755 81 GLTAYVTRDpdTKQLVLESGALVLSDGGICCIDEFDKMSDSTRSVLHEVMEQQTLSIAKAGIITTLNARTSILASANPIG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 464 -HYDPAESVSVNIALGSPLLSRFDLVLVLLDTKNEEWDRIISSFI----LQNKGcPSKSEKLWSMEKMKTYFCLIK-RIQ 537
Cdd:cd17755 161 sRYNPKLTVVENIDLPPTLLSRFDLIYLVLDKVDEKYDRRLAKHLvslyLEDTP-EHIQDEVLDVEVLTDYISYAReHIH 239
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 538 PKLSDESNLILVRYYQMQRQ--SDCRNAARTTIRLLESLIRLAEAHARLMFRDTVTLEDAVTVVSVMESS 605
Cdd:cd17755 240 PKLSEEAAQELVQAYVDMRKmgSDARKRITATPRQLESLIRLAEAHAKMRLSNVVEAEDVEEAVRLIREA 309
|
|
| MCM5 |
cd17756 |
DNA replication licensing factor Mcm5; Mcm5 is a helicase that play an important role in ... |
308-595 |
2.59e-82 |
|
DNA replication licensing factor Mcm5; Mcm5 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350662 [Multi-domain] Cd Length: 317 Bit Score: 271.56 E-value: 2.59e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 308 ILASLCPQVFGLYLVKLAVAMVLAGGVQRIDATGTRIRGESHLLLVGDPGTGKSQFLKYAVKITPRSVLTAGIGSTSAGL 387
Cdd:cd17756 2 ISKSIAPSIYGNEDIKKAIACLLFGGSRKRLPDGMRLRGDINVLLLGDPGTAKSQLLKFVEKVAPIGVYTSGKGSSAAGL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 388 TVTAVKD--FGEWNLEAGALVLADGGLCCIDEFNSIKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPK-GH 464
Cdd:cd17756 82 TASVMRDpsTREFYLEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRTSVLAAANPVfGR 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 465 YDPAESVSVNIALGSPLLSRFDLVLVLLDTKNEEWDRIISSFIL------QNKGCPSKSEKLWSMEKMKTYFCLIK-RIQ 537
Cdd:cd17756 162 YDDLKTPGDNIDFQTTILSRFDMIFIVKDKHDEERDITIAKHVInihasaRKASQSQENEGEIPISKLKRYIAYCRaKCA 241
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2163339433 538 PKLSDESNLILVRYY--------QMQRQSDCRNAARTTIRLLESLIRLAEAHARLMFRDTVTLEDA 595
Cdd:cd17756 242 PRLSEEAAEKLSNHYvtirkdvrQNELESDNRSSIPITVRQLEAIIRISESLAKMELSPIATEKHV 307
|
|
| MCM3 |
cd17754 |
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in ... |
311-602 |
2.07e-79 |
|
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350660 [Multi-domain] Cd Length: 299 Bit Score: 262.79 E-value: 2.07e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 311 SLCPQVFGLYLVKLAVAMVLAGGVQRIDATGTRIRGESHLLLVGDPGTGKSQFLKYAVKITPRSVLTAGIGSTSAGLT-- 388
Cdd:cd17754 5 SLAPSIYGHEYIKKAILLMLLGGVEKNLENGSHLRGDINILLVGDPSVAKSQLLRYVLNTAPLAIATTGRGSSGVGLTaa 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 389 VTAVKDFGEWNLEAGALVLADGGLCCIDEFNSIKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNP-KGHYDP 467
Cdd:cd17754 85 VTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDIDRVAIHEVMEQQTVTIAKAGIHASLNARCSVLAAANPvYGRYDV 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 468 AESVSVNIALGSPLLSRFDLVLVLLDTKNEEWDRIISSFILQNKGcpskseklwSMEKMKTYFCLIK-RIQPKLSDESNL 546
Cdd:cd17754 165 YKTPMENIGLPDSLLSRFDLLFIVLDDIDEERDRSISEHVLRMHR---------YIKFLRKYIHYAKeRIKPKLTQEAAE 235
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2163339433 547 ILVRYYQMQRQSDC--RNAART---TIRLLESLIRLAEAHARLMFRDTVTLEDAVTVVSVM 602
Cdd:cd17754 236 YIAEEYADLRNDDNtkTDKARTspiTARTLETLIRLATAHAKARLSKTVDKVDAEVALNLL 296
|
|
| MCM8 |
cd17759 |
DNA helicase Mcm8; Mcm8 plays an important role homologous recombination repair. It forms a ... |
308-605 |
7.69e-77 |
|
DNA helicase Mcm8; Mcm8 plays an important role homologous recombination repair. It forms a complex with Mcm9 that is required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350665 [Multi-domain] Cd Length: 289 Bit Score: 255.15 E-value: 7.69e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 308 ILASLCPQVFGLYLVKLAVAMVLAGGVQRI--DATGTRIRGESHLLLVGDPGTGKSQFLKYAVKITPRSVLTAGIGSTSA 385
Cdd:cd17759 2 IVNSLCPAIYGHELVKAGLLLSLFGGKQKYadDKNRIPIRGDPHVLIVGDPGLGKSQMLQAACNIAPRGVYVCGNTTTTS 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 386 GLTVTAVKD--FGEWNLEAGALVLADGGLCCIDEFNSI-KEHdrTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPK 462
Cdd:cd17759 82 GLTVTLTKDgrSGDFALEAGALVLGDQGICGIDEFDKMgSQH--QALLEAMEQQSVSLAKAGVVCSLPARTSVIAAANPV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 463 -GHYDPAESVSVNIALGSPLLSRFDLVLVLLDTKNEEWDRIISSfilqnkgcpskseklwSMEKMKTYFCLIKR-IQPKL 540
Cdd:cd17759 160 gGHYNKGKTVSENLKMGPALLSRFDLVFILLDTPSEEHDHLLSE----------------HHQLLRKYISYARQyVNPVL 223
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2163339433 541 SDESNLILVRYY-QMQRQSDCRNAARTTIRLLESLIRLAEAHARLMFRDTVTLEDAVTVVSVMESS 605
Cdd:cd17759 224 SKDASEALQEFYlELRKQNQLADSSPITTRQLESLIRLTEARARLELREEATKEDAEDVIEIMKES 289
|
|
| PTZ00111 |
PTZ00111 |
DNA replication licensing factor MCM4; Provisional |
226-605 |
4.23e-58 |
|
DNA replication licensing factor MCM4; Provisional
Pssm-ID: 173403 [Multi-domain] Cd Length: 915 Bit Score: 217.55 E-value: 4.23e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 226 LEDDLVDSCKSGDDITVYGVVmqRWKPFHQDARCDLELVLKANYVKVNNEQLAGVTIDEEVRKEFE------DFWE---- 295
Cdd:PTZ00111 352 LYDDLIDSVKTGDRVTVVGIL--KVTPIRTSTTRRTLKSLYTYFVNVIHVKVINSTNANQPEKGLKylgnenDFSDlqvy 429
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 296 ---KHRNNPLAGRnEILASLCPQVFGLYLVKLAVAMVLAGGVQRIDATGT---------RIRGESHLLLVGDPGTGKSQF 363
Cdd:PTZ00111 430 kilELSRNPMIYR-ILLDSFAPSIKARNNVKIGLLCQLFSGNKNSSDFNKspdacykvdNFRGIINVLLCGDPGTAKSQL 508
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 364 LKYAVKITPRSVLTAGIGSTSAGLTVTAV---KDFGEWNLEAGALVLADGGLCCIDEFNSIKEHDRTSIHEAMEQQTISV 440
Cdd:PTZ00111 509 LHYTHLLSPRSIYTSGKSSSSVGLTASIKfneSDNGRAMIQPGAVVLANGGVCCIDELDKCHNESRLSLYEVMEQQTVTI 588
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 441 AKAGLVCKLNTRTTILAATNP-KGHYDPAESVSVNIALGSPLLSRFDLVLVLLDTKNEEWDRIISSFILQNKGCPS---- 515
Cdd:PTZ00111 589 AKAGIVATLKAETAILASCNPiNSRYNKNKAVIENINISPSLFTRFDLIYLVLDHIDQDTDQLISLSIAKDFLLPHmtgs 668
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 516 --------------------KSEKLWSMEKMKTYFCLIK--RIQ--PKLSDESNLILVRYYQMQRQSD------------ 559
Cdd:PTZ00111 669 gndedtydrsntmhvedeslRSEKDYNKNDLDMLRMYIKfsKLHcfPKLSDEAKKVITREYVKMRQGNfqtsnldeleha 748
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*....
gi 2163339433 560 ----------CRNAART---TIRLLESLIRLAEAHARLMFRDTVTLEDAVTVVSVMESS 605
Cdd:PTZ00111 749 qedddddlyyQSSGTRMiyvSSRMISSIIRISVSLARMRLSTVVTPADALQAVQIVKSS 807
|
|
| MCM_OB |
pfam17207 |
MCM OB domain; This family contains an OB-fold found within MCM proteins. This domain contains ... |
118-245 |
3.16e-23 |
|
MCM OB domain; This family contains an OB-fold found within MCM proteins. This domain contains an insertion at the zinc binding motif.
Pssm-ID: 465381 [Multi-domain] Cd Length: 126 Bit Score: 96.01 E-value: 3.16e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 118 KTRDVGHFLSVTGTVIRTSLVKVLEFERSYICNKCKHVFVAKadfeqyyaFCRPSACLNEEgCNST-KFTCLSGTSSsps 196
Cdd:pfam17207 6 RSEHIGKLVSVSGIVTRTSEVRPKLKKATFTCRKCGHTVGVK--------ITEPTKCPNPE-CGNKdPFKLVHEKSK--- 73
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 2163339433 197 sCRDYQEIKIQEQVQRLSVGSIPRCMVVVLEDDLVDSCKSGDDITVYGV 245
Cdd:pfam17207 74 -FVDFQKIKIQESPEEVPAGELPRSLDVILDDDLVDRVKPGDRVTVTGI 121
|
|
| MCM_lid |
pfam17855 |
MCM AAA-lid domain; This entry represents the AAA-lid domain found in MCM proteins. |
534-606 |
2.86e-17 |
|
MCM AAA-lid domain; This entry represents the AAA-lid domain found in MCM proteins.
Pssm-ID: 465534 [Multi-domain] Cd Length: 86 Bit Score: 77.58 E-value: 2.86e-17
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2163339433 534 KRIQPKLSDESNLILVRYY-QM-QRQSDCRNAARTTIRLLESLIRLAEAHARLMFRDTVTLEDAVTVVSVMESSM 606
Cdd:pfam17855 12 EKIKPKLSEEAREKLVDAYvELrKESTGSGSSIPITVRQLESLIRLSEAHAKMRLSEIVTEEDVEEAIRLLKESL 86
|
|
| AAA_5 |
pfam07728 |
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not ... |
349-485 |
1.94e-08 |
|
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.
Pssm-ID: 400191 [Multi-domain] Cd Length: 135 Bit Score: 54.22 E-value: 1.94e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 349 HLLLVGDPGTGKSQFLK-YAVKITPRSVLTAGIgstSAGLTVTAVkdFGEWNLEAGALVLADGGL---------CCIDEF 418
Cdd:pfam07728 1 GVLLVGPPGTGKTELAErLAAALSNRPVFYVQL---TRDTTEEDL--FGRRNIDPGGASWVDGPLvraaregeiAVLDEI 75
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2163339433 419 NSIKEHDRTSIHEAMEQQTISVAKAG-LVCKLNTRTTILAATNPkGHYDPAEsvsvniaLGSPLLSRF 485
Cdd:pfam07728 76 NRANPDVLNSLLSLLDERRLLLPDGGeLVKAAPDGFRLIATMNP-LDRGLNE-------LSPALRSRF 135
|
|
| AAA |
cd00009 |
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ... |
348-491 |
4.19e-04 |
|
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.
Pssm-ID: 99707 [Multi-domain] Cd Length: 151 Bit Score: 42.13 E-value: 4.19e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 348 SHLLLVGDPGTGKSQFLKYAVKITPRSVLTAgIGSTSAGLTVTAV--KDFGEWNLEAGALVLADGGLCC--IDEFNSIKE 423
Cdd:cd00009 20 KNLLLYGPPGTGKTTLARAIANELFRPGAPF-LYLNASDLLEGLVvaELFGHFLVRLLFELAEKAKPGVlfIDEIDSLSR 98
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2163339433 424 HDRTSIHEAMEQQTISVakaglvcKLNTRTTILAATNPKGHYDPAEsvsvnialgsPLLSRFDLVLVL 491
Cdd:cd00009 99 GAQNALLRVLETLNDLR-------IDRENVRVIGATNRPLLGDLDR----------ALYDRLDIRIVI 149
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
349-493 |
5.28e-04 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 41.59 E-value: 5.28e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 349 HLLLVGDPGTGKSQFLK----YAVKITPRSVLTAGIGSTSAGLTVTAVKDFGEWNLE-------AGALVLA---DGGLCC 414
Cdd:smart00382 4 VILIVGPPGSGKTTLARalarELGPPGGGVIYIDGEDILEEVLDQLLLIIVGGKKASgsgelrlRLALALArklKPDVLI 83
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2163339433 415 IDEFNSIKEHDRtsiheAMEQQTISVAKAGLVCKLNTRTTILAATNPKGHYDPAEsvsvnialgspLLSRFDLVLVLLD 493
Cdd:smart00382 84 LDEITSLLDAEQ-----EALLLLLEELRLLLLLKSEKNLTVILTTNDEKDLGPAL-----------LRRRFDRRIVLLL 146
|
|
| COG1223 |
COG1223 |
Predicted ATPase, AAA+ superfamily [General function prediction only]; |
349-569 |
5.12e-03 |
|
Predicted ATPase, AAA+ superfamily [General function prediction only];
Pssm-ID: 440836 [Multi-domain] Cd Length: 246 Bit Score: 39.87 E-value: 5.12e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 349 HLLLVGDPGTGKSQFLK----------YAVKITprSVLTAGIGSTSAGLtvTAVKDFGEwnlEAGALVLadgglccIDEF 418
Cdd:COG1223 37 KILFYGPPGTGKTMLAEalagelklplLTVRLD--SLIGSYLGETARNL--RKLFDFAR---RAPCVIF-------FDEF 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2163339433 419 NSIKeHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPKGHYDPAesvsvnialgspLLSRFDLVLVLLDTKNEE 498
Cdd:COG1223 103 DAIA-KDRGDQNDVGEVKRVVNALLQELDGLPSGSVVIAATNHPELLDSA------------LWRRFDEVIEFPLPDKEE 169
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2163339433 499 WDRIISSFIlqnKGCPSKSEKLWsmekmktyfcliKRIQPKLSDESNLILVRYyqmqrqsdCRNAARTTIR 569
Cdd:COG1223 170 RKEILELNL---KKFPLPFELDL------------KKLAKKLEGLSGADIEKV--------LKTALKKAIL 217
|
|
| |
