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Conserved domains on  [gi|110347412|ref|NP_003564|]
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latent-transforming growth factor beta-binding protein 4 isoform b [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TB pfam00683
TB domain; This domain is also known as the 8 cysteine domain. This family includes the hybrid ...
 381-422 3.72e-11

TB domain; This domain is also known as the 8 cysteine domain. This family includes the hybrid domains. This cysteine rich repeat is found in TGF binding protein and fibrillin.


:

Pssm-ID: 459903  Cd Length: 44  Bit Score: 59.21  E-value: 3.72e-11
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 110347412   381 CSLPILRNITKQICCCSRVGKAWGRGCQLCPPFGSEGFREIC 422
Cdd:pfam00683    3 CSNPLPGNVTKSECCCTSVGRAWGSPCELCPPPGTDEFRELC 44
TB pfam00683
TB domain; This domain is also known as the 8 cysteine domain. This family includes the hybrid ...
 1323-1365 1.75e-07

TB domain; This domain is also known as the 8 cysteine domain. This family includes the hybrid domains. This cysteine rich repeat is found in TGF binding protein and fibrillin.


:

Pssm-ID: 459903  Cd Length: 44  Bit Score: 48.81  E-value: 1.75e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 110347412  1323 VCSHPrLDRQATYTECCCLY-GEAWGMDCALCPAQDSDDFEALC 1365
Cdd:pfam00683    2 RCSNP-LPGNVTKSECCCTSvGRAWGSPCELCPPPGTDEFRELC 44
TB pfam00683
TB domain; This domain is also known as the 8 cysteine domain. This family includes the hybrid ...
 1156-1198 4.90e-07

TB domain; This domain is also known as the 8 cysteine domain. This family includes the hybrid domains. This cysteine rich repeat is found in TGF binding protein and fibrillin.


:

Pssm-ID: 459903  Cd Length: 44  Bit Score: 47.66  E-value: 4.90e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 110347412  1156 CDNILARNVTWQECCC-TVGEGWGSGCriQQCPGTETAEYQSLC 1198
Cdd:pfam00683    3 CSNPLPGNVTKSECCCtSVGRAWGSPC--ELCPPPGTDEFRELC 44
EGF_CA smart00179
Calcium-binding EGF-like domain;
841-877 8.95e-07

Calcium-binding EGF-like domain;


:

Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 46.86  E-value: 8.95e-07
                            10        20        30
                    ....*....|....*....|....*....|....*..
gi 110347412    841 DVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPR 877
Cdd:smart00179    1 DIDECASGNPCQNGGTCVNTVGSYRCECPPGYTDGRN 37
EGF_CA smart00179
Calcium-binding EGF-like domain;
797-830 1.16e-06

Calcium-binding EGF-like domain;


:

Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 46.47  E-value: 1.16e-06
                            10        20        30
                    ....*....|....*....|....*....|....
gi 110347412    797 DVDECSSGaPPCGPHGHCTNTEGSFRCSCAPGYR 830
Cdd:smart00179    1 DIDECASG-NPCQNGGTCVNTVGSYRCECPPGYT 33
EGF_CA smart00179
Calcium-binding EGF-like domain;
1012-1053 1.39e-06

Calcium-binding EGF-like domain;


:

Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 46.09  E-value: 1.39e-06
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|..
gi 110347412   1012 DVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEgarDGRHCV 1053
Cdd:smart00179    1 DIDECASGNPCQNGGTCVNTVGSYRCECPPGYT---DGRNCE 39
EGF_CA smart00179
Calcium-binding EGF-like domain;
883-918 6.82e-06

Calcium-binding EGF-like domain;


:

Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 44.16  E-value: 6.82e-06
                            10        20        30
                    ....*....|....*....|....*....|....*..
gi 110347412    883 DVDECSEEDLCQSG-ICTNTDGSFECICPPGHRAGPD 918
Cdd:smart00179    1 DIDECASGNPCQNGgTCVNTVGSYRCECPPGYTDGRN 37
EGF_CA cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ...
 634-671 1.88e-05

Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements.


:

Pssm-ID: 238011  Cd Length: 38  Bit Score: 43.01  E-value: 1.88e-05
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 110347412  634 DVDECtQSPGLCGRGA-CKNLPGSFRCVCPAGFRGSACE 671
Cdd:cd00054     1 DIDEC-ASGNPCQNGGtCVNTVGSYRCSCPPGYTGRNCE 38
EGF_CA smart00179
Calcium-binding EGF-like domain;
320-350 2.89e-05

Calcium-binding EGF-like domain;


:

Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 42.62  E-value: 2.89e-05
                            10        20        30
                    ....*....|....*....|....*....|..
gi 110347412    320 DVDECATGGRCQHG-ECANTRGGYTCVCPDGF 350
Cdd:smart00179    1 DIDECASGNPCQNGgTCVNTVGSYRCECPPGY 32
EGF_CA smart00179
Calcium-binding EGF-like domain;
715-756 1.30e-04

Calcium-binding EGF-like domain;


:

Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 40.69  E-value: 1.30e-04
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|...
gi 110347412    715 DVDECArSPPPCTYG-RCENTEGSFQCVCPMGFqpnTAGSECE 756
Cdd:smart00179    1 DIDECA-SGNPCQNGgTCVNTVGSYRCECPPGY---TDGRNCE 39
EGF_CA smart00179
Calcium-binding EGF-like domain;
550-586 2.48e-04

Calcium-binding EGF-like domain;


:

Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 39.92  E-value: 2.48e-04
                            10        20        30
                    ....*....|....*....|....*....|....*...
gi 110347412    550 DVDECRRvPPPCAPG-RCENSPGSFRCVCGPGFRAGPR 586
Cdd:smart00179    1 DIDECAS-GNPCQNGgTCVNTVGSYRCECPPGYTDGRN 37
EGF_CA smart00179
Calcium-binding EGF-like domain;
592-633 4.94e-04

Calcium-binding EGF-like domain;


:

Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 39.15  E-value: 4.94e-04
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|..
gi 110347412    592 DVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAaphGASCQ 633
Cdd:smart00179    1 DIDECASGNPCQNGGTCVNTVGSYRCECPPGYTD---GRNCE 39
EGF_CA smart00179
Calcium-binding EGF-like domain;
673-707 1.02e-03

Calcium-binding EGF-like domain;


:

Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 38.00  E-value: 1.02e-03
                            10        20        30
                    ....*....|....*....|....*....|....*.
gi 110347412    673 DVDECAqEPPPCGPG-RCDNTAGSFHCACPAGFRSR 707
Cdd:smart00179    1 DIDECA-SGNPCQNGgTCVNTVGSYRCECPPGYTDG 35
EGF_CA cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ...
 1259-1288 1.80e-03

Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements.


:

Pssm-ID: 238011  Cd Length: 38  Bit Score: 37.62  E-value: 1.80e-03
                          10        20        30
                  ....*....|....*....|....*....|
gi 110347412 1259 DNDECADEEPACEGGRCVNTVGSYHCTCEP 1288
Cdd:cd00054     1 DIDECASGNPCQNGGTCVNTVGSYRCSCPP 30
EGF_CA smart00179
Calcium-binding EGF-like domain;
1537-1571 2.32e-03

Calcium-binding EGF-like domain;


:

Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 37.23  E-value: 2.32e-03
                            10        20        30
                    ....*....|....*....|....*....|....*.
gi 110347412   1537 DINECDEaeaaSPLCVN-ARCLNTDGSFRCICRPGF 1571
Cdd:smart00179    1 DIDECAS----GNPCQNgGTCVNTVGSYRCECPPGY 32
EGF_CA smart00179
Calcium-binding EGF-like domain;
924-962 3.08e-03

Calcium-binding EGF-like domain;


:

Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 36.84  E-value: 3.08e-03
                            10        20        30
                    ....*....|....*....|....*....|....*....
gi 110347412    924 DVDECRERGPALCGSqRCENSPGSYRCvrDCDPGYHAGP 962
Cdd:smart00179    1 DIDECASGNPCQNGG-TCVNTVGSYRC--ECPPGYTDGR 36
EGF_CA smart00179
Calcium-binding EGF-like domain;
968-1011 3.44e-03

Calcium-binding EGF-like domain;


:

Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 36.84  E-value: 3.44e-03
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....
gi 110347412    968 DVDECQEYGPEICGAqRCENTPGSYRCTpaCDPGYqpTPGGGCQ 1011
Cdd:smart00179    1 DIDECASGNPCQNGG-TCVNTVGSYRCE--CPPGY--TDGRNCE 39
 
Name Accession Description Interval E-value
TB pfam00683
TB domain; This domain is also known as the 8 cysteine domain. This family includes the hybrid ...
 381-422 3.72e-11

TB domain; This domain is also known as the 8 cysteine domain. This family includes the hybrid domains. This cysteine rich repeat is found in TGF binding protein and fibrillin.


Pssm-ID: 459903  Cd Length: 44  Bit Score: 59.21  E-value: 3.72e-11
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 110347412   381 CSLPILRNITKQICCCSRVGKAWGRGCQLCPPFGSEGFREIC 422
Cdd:pfam00683    3 CSNPLPGNVTKSECCCTSVGRAWGSPCELCPPPGTDEFRELC 44
TB pfam00683
TB domain; This domain is also known as the 8 cysteine domain. This family includes the hybrid ...
 1323-1365 1.75e-07

TB domain; This domain is also known as the 8 cysteine domain. This family includes the hybrid domains. This cysteine rich repeat is found in TGF binding protein and fibrillin.


Pssm-ID: 459903  Cd Length: 44  Bit Score: 48.81  E-value: 1.75e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 110347412  1323 VCSHPrLDRQATYTECCCLY-GEAWGMDCALCPAQDSDDFEALC 1365
Cdd:pfam00683    2 RCSNP-LPGNVTKSECCCTSvGRAWGSPCELCPPPGTDEFRELC 44
TB pfam00683
TB domain; This domain is also known as the 8 cysteine domain. This family includes the hybrid ...
 1156-1198 4.90e-07

TB domain; This domain is also known as the 8 cysteine domain. This family includes the hybrid domains. This cysteine rich repeat is found in TGF binding protein and fibrillin.


Pssm-ID: 459903  Cd Length: 44  Bit Score: 47.66  E-value: 4.90e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 110347412  1156 CDNILARNVTWQECCC-TVGEGWGSGCriQQCPGTETAEYQSLC 1198
Cdd:pfam00683    3 CSNPLPGNVTKSECCCtSVGRAWGSPC--ELCPPPGTDEFRELC 44
EGF_CA smart00179
Calcium-binding EGF-like domain;
841-877 8.95e-07

Calcium-binding EGF-like domain;


Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 46.86  E-value: 8.95e-07
                            10        20        30
                    ....*....|....*....|....*....|....*..
gi 110347412    841 DVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPR 877
Cdd:smart00179    1 DIDECASGNPCQNGGTCVNTVGSYRCECPPGYTDGRN 37
EGF_CA smart00179
Calcium-binding EGF-like domain;
797-830 1.16e-06

Calcium-binding EGF-like domain;


Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 46.47  E-value: 1.16e-06
                            10        20        30
                    ....*....|....*....|....*....|....
gi 110347412    797 DVDECSSGaPPCGPHGHCTNTEGSFRCSCAPGYR 830
Cdd:smart00179    1 DIDECASG-NPCQNGGTCVNTVGSYRCECPPGYT 33
EGF_CA smart00179
Calcium-binding EGF-like domain;
1012-1053 1.39e-06

Calcium-binding EGF-like domain;


Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 46.09  E-value: 1.39e-06
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|..
gi 110347412   1012 DVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEgarDGRHCV 1053
Cdd:smart00179    1 DIDECASGNPCQNGGTCVNTVGSYRCECPPGYT---DGRNCE 39
EGF_CA cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ...
 797-830 1.84e-06

Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements.


Pssm-ID: 238011  Cd Length: 38  Bit Score: 45.71  E-value: 1.84e-06
                          10        20        30
                  ....*....|....*....|....*....|....
gi 110347412  797 DVDECSSGaPPCGPHGHCTNTEGSFRCSCAPGYR 830
Cdd:cd00054     1 DIDECASG-NPCQNGGTCVNTVGSYRCSCPPGYT 33
EGF_CA cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ...
 1012-1047 5.20e-06

Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements.


Pssm-ID: 238011  Cd Length: 38  Bit Score: 44.55  E-value: 5.20e-06
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 110347412 1012 DVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGAR 1047
Cdd:cd00054     1 DIDECASGNPCQNGGTCVNTVGSYRCSCPPGYTGRN 36
EGF_CA smart00179
Calcium-binding EGF-like domain;
883-918 6.82e-06

Calcium-binding EGF-like domain;


Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 44.16  E-value: 6.82e-06
                            10        20        30
                    ....*....|....*....|....*....|....*..
gi 110347412    883 DVDECSEEDLCQSG-ICTNTDGSFECICPPGHRAGPD 918
Cdd:smart00179    1 DIDECASGNPCQNGgTCVNTVGSYRCECPPGYTDGRN 37
EGF_CA cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ...
 841-873 1.47e-05

Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements.


Pssm-ID: 238011  Cd Length: 38  Bit Score: 43.39  E-value: 1.47e-05
                          10        20        30
                  ....*....|....*....|....*....|...
gi 110347412  841 DVNECLEGDFCFPHGECLNTDGSFACTCAPGYR 873
Cdd:cd00054     1 DIDECASGNPCQNGGTCVNTVGSYRCSCPPGYT 33
EGF_CA cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ...
 634-671 1.88e-05

Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements.


Pssm-ID: 238011  Cd Length: 38  Bit Score: 43.01  E-value: 1.88e-05
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 110347412  634 DVDECtQSPGLCGRGA-CKNLPGSFRCVCPAGFRGSACE 671
Cdd:cd00054     1 DIDEC-ASGNPCQNGGtCVNTVGSYRCSCPPGYTGRNCE 38
EGF_CA smart00179
Calcium-binding EGF-like domain;
320-350 2.89e-05

Calcium-binding EGF-like domain;


Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 42.62  E-value: 2.89e-05
                            10        20        30
                    ....*....|....*....|....*....|..
gi 110347412    320 DVDECATGGRCQHG-ECANTRGGYTCVCPDGF 350
Cdd:smart00179    1 DIDECASGNPCQNGgTCVNTVGSYRCECPPGY 32
EGF_CA pfam07645
Calcium-binding EGF domain;
797-828 3.01e-05

Calcium-binding EGF domain;


Pssm-ID: 429571  Cd Length: 32  Bit Score: 42.22  E-value: 3.01e-05
                           10        20        30
                   ....*....|....*....|....*....|..
gi 110347412   797 DVDECSSGAPPCGPHGHCTNTEGSFRCSCAPG 828
Cdd:pfam07645    1 DVDECATGTHNCPANTVCVNTIGSFECRCPDG 32
EGF_CA cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ...
 883-914 6.12e-05

Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements.


Pssm-ID: 238011  Cd Length: 38  Bit Score: 41.47  E-value: 6.12e-05
                          10        20        30
                  ....*....|....*....|....*....|...
gi 110347412  883 DVDECSEEDLCQ-SGICTNTDGSFECICPPGHR 914
Cdd:cd00054     1 DIDECASGNPCQnGGTCVNTVGSYRCSCPPGYT 33
EGF_CA smart00179
Calcium-binding EGF-like domain;
634-671 8.59e-05

Calcium-binding EGF-like domain;


Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 41.08  E-value: 8.59e-05
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|
gi 110347412    634 DVDECtQSPGLCGRGA-CKNLPGSFRCVCPAGFR-GSACE 671
Cdd:smart00179    1 DIDEC-ASGNPCQNGGtCVNTVGSYRCECPPGYTdGRNCE 39
EGF_CA cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ...
 320-354 1.09e-04

Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements.


Pssm-ID: 238011  Cd Length: 38  Bit Score: 40.70  E-value: 1.09e-04
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 110347412  320 DVDECATGGRCQ-HGECANTRGGYTCVCPDGFLLDS 354
Cdd:cd00054     1 DIDECASGNPCQnGGTCVNTVGSYRCSCPPGYTGRN 36
EGF_CA smart00179
Calcium-binding EGF-like domain;
715-756 1.30e-04

Calcium-binding EGF-like domain;


Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 40.69  E-value: 1.30e-04
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|...
gi 110347412    715 DVDECArSPPPCTYG-RCENTEGSFQCVCPMGFqpnTAGSECE 756
Cdd:smart00179    1 DIDECA-SGNPCQNGgTCVNTVGSYRCECPPGY---TDGRNCE 39
EGF_CA smart00179
Calcium-binding EGF-like domain;
550-586 2.48e-04

Calcium-binding EGF-like domain;


Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 39.92  E-value: 2.48e-04
                            10        20        30
                    ....*....|....*....|....*....|....*...
gi 110347412    550 DVDECRRvPPPCAPG-RCENSPGSFRCVCGPGFRAGPR 586
Cdd:smart00179    1 DIDECAS-GNPCQNGgTCVNTVGSYRCECPPGYTDGRN 37
EGF_CA smart00179
Calcium-binding EGF-like domain;
592-633 4.94e-04

Calcium-binding EGF-like domain;


Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 39.15  E-value: 4.94e-04
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|..
gi 110347412    592 DVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAaphGASCQ 633
Cdd:smart00179    1 DIDECASGNPCQNGGTCVNTVGSYRCECPPGYTD---GRNCE 39
EGF_CA pfam07645
Calcium-binding EGF domain;
883-912 7.99e-04

Calcium-binding EGF domain;


Pssm-ID: 429571  Cd Length: 32  Bit Score: 38.37  E-value: 7.99e-04
                           10        20        30
                   ....*....|....*....|....*....|..
gi 110347412   883 DVDEC-SEEDLC-QSGICTNTDGSFECICPPG 912
Cdd:pfam07645    1 DVDECaTGTHNCpANTVCVNTIGSFECRCPDG 32
EGF_3 pfam12947
EGF domain; This family includes a variety of EGF-like domain homologs. This family includes ...
 1022-1052 1.02e-03

EGF domain; This family includes a variety of EGF-like domain homologs. This family includes the C-terminal domain of the malaria parasite MSP1 protein.


Pssm-ID: 463759 [Multi-domain]  Cd Length: 36  Bit Score: 37.96  E-value: 1.02e-03
                           10        20        30
                   ....*....|....*....|....*....|.
gi 110347412  1022 CGAHAVCQNLPGSFQCLCDQGYEGarDGRHC 1052
Cdd:pfam12947    8 CHPNATCTNTGGSFTCTCNDGYTG--DGVTC 36
EGF_CA smart00179
Calcium-binding EGF-like domain;
673-707 1.02e-03

Calcium-binding EGF-like domain;


Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 38.00  E-value: 1.02e-03
                            10        20        30
                    ....*....|....*....|....*....|....*.
gi 110347412    673 DVDECAqEPPPCGPG-RCDNTAGSFHCACPAGFRSR 707
Cdd:smart00179    1 DIDECA-SGNPCQNGgTCVNTVGSYRCECPPGYTDG 35
EGF_CA cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ...
 715-750 1.08e-03

Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements.


Pssm-ID: 238011  Cd Length: 38  Bit Score: 38.00  E-value: 1.08e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 110347412  715 DVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNT 750
Cdd:cd00054     1 DIDECASGNPCQNGGTCVNTVGSYRCSCPPGYTGRN 36
EGF_CA cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ...
 673-707 1.17e-03

Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements.


Pssm-ID: 238011  Cd Length: 38  Bit Score: 38.00  E-value: 1.17e-03
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 110347412  673 DVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSR 707
Cdd:cd00054     1 DIDECASGNPCQNGGTCVNTVGSYRCSCPPGYTGR 35
EGF_CA cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ...
 1259-1288 1.80e-03

Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements.


Pssm-ID: 238011  Cd Length: 38  Bit Score: 37.62  E-value: 1.80e-03
                          10        20        30
                  ....*....|....*....|....*....|
gi 110347412 1259 DNDECADEEPACEGGRCVNTVGSYHCTCEP 1288
Cdd:cd00054     1 DIDECASGNPCQNGGTCVNTVGSYRCSCPP 30
EGF_CA smart00179
Calcium-binding EGF-like domain;
1259-1288 2.04e-03

Calcium-binding EGF-like domain;


Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 37.23  E-value: 2.04e-03
                            10        20        30
                    ....*....|....*....|....*....|
gi 110347412   1259 DNDECADEEPACEGGRCVNTVGSYHCTCEP 1288
Cdd:smart00179    1 DIDECASGNPCQNGGTCVNTVGSYRCECPP 30
EGF_CA pfam07645
Calcium-binding EGF domain;
320-349 2.20e-03

Calcium-binding EGF domain;


Pssm-ID: 429571  Cd Length: 32  Bit Score: 37.22  E-value: 2.20e-03
                           10        20        30
                   ....*....|....*....|....*....|..
gi 110347412   320 DVDECATGGR-CQHGE-CANTRGGYTCVCPDG 349
Cdd:pfam07645    1 DVDECATGTHnCPANTvCVNTIGSFECRCPDG 32
EGF_CA smart00179
Calcium-binding EGF-like domain;
1537-1571 2.32e-03

Calcium-binding EGF-like domain;


Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 37.23  E-value: 2.32e-03
                            10        20        30
                    ....*....|....*....|....*....|....*.
gi 110347412   1537 DINECDEaeaaSPLCVN-ARCLNTDGSFRCICRPGF 1571
Cdd:smart00179    1 DIDECAS----GNPCQNgGTCVNTVGSYRCECPPGY 32
EGF_CA cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ...
 592-633 3.06e-03

Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements.


Pssm-ID: 238011  Cd Length: 38  Bit Score: 36.85  E-value: 3.06e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 110347412  592 DVDECHRVPPPCDLGRCENTPGSFLCVCPAGYqaapHGASCQ 633
Cdd:cd00054     1 DIDECASGNPCQNGGTCVNTVGSYRCSCPPGY----TGRNCE 38
EGF_CA smart00179
Calcium-binding EGF-like domain;
924-962 3.08e-03

Calcium-binding EGF-like domain;


Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 36.84  E-value: 3.08e-03
                            10        20        30
                    ....*....|....*....|....*....|....*....
gi 110347412    924 DVDECRERGPALCGSqRCENSPGSYRCvrDCDPGYHAGP 962
Cdd:smart00179    1 DIDECASGNPCQNGG-TCVNTVGSYRC--ECPPGYTDGR 36
EGF_CA cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ...
 550-582 3.19e-03

Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements.


Pssm-ID: 238011  Cd Length: 38  Bit Score: 36.85  E-value: 3.19e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 110347412  550 DVDECRRVPPPCAPGRCENSPGSFRCVCGPGFR 582
Cdd:cd00054     1 DIDECASGNPCQNGGTCVNTVGSYRCSCPPGYT 33
EGF_CA smart00179
Calcium-binding EGF-like domain;
968-1011 3.44e-03

Calcium-binding EGF-like domain;


Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 36.84  E-value: 3.44e-03
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....
gi 110347412    968 DVDECQEYGPEICGAqRCENTPGSYRCTpaCDPGYqpTPGGGCQ 1011
Cdd:smart00179    1 DIDECASGNPCQNGG-TCVNTVGSYRCE--CPPGY--TDGRNCE 39
EGF_CA cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ...
 1537-1575 4.92e-03

Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements.


Pssm-ID: 238011  Cd Length: 38  Bit Score: 36.08  E-value: 4.92e-03
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 110347412 1537 DINECDEAeaaSPLCVNARCLNTDGSFRCICRPGFAPTH 1575
Cdd:cd00054     1 DIDECASG---NPCQNGGTCVNTVGSYRCSCPPGYTGRN 36
EGF_CA pfam07645
Calcium-binding EGF domain;
715-745 7.09e-03

Calcium-binding EGF domain;


Pssm-ID: 429571  Cd Length: 32  Bit Score: 35.68  E-value: 7.09e-03
                           10        20        30
                   ....*....|....*....|....*....|..
gi 110347412   715 DVDECARSPPPCTY-GRCENTEGSFQCVCPMG 745
Cdd:pfam07645    1 DVDECATGTHNCPAnTVCVNTIGSFECRCPDG 32
EGF_CA pfam07645
Calcium-binding EGF domain;
1537-1570 9.25e-03

Calcium-binding EGF domain;


Pssm-ID: 429571  Cd Length: 32  Bit Score: 35.29  E-value: 9.25e-03
                           10        20        30
                   ....*....|....*....|....*....|....
gi 110347412  1537 DINECDEAEAASPlcVNARCLNTDGSFRCICRPG 1570
Cdd:pfam07645    1 DVDECATGTHNCP--ANTVCVNTIGSFECRCPDG 32
 
Name Accession Description Interval E-value
TB pfam00683
TB domain; This domain is also known as the 8 cysteine domain. This family includes the hybrid ...
 381-422 3.72e-11

TB domain; This domain is also known as the 8 cysteine domain. This family includes the hybrid domains. This cysteine rich repeat is found in TGF binding protein and fibrillin.


Pssm-ID: 459903  Cd Length: 44  Bit Score: 59.21  E-value: 3.72e-11
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 110347412   381 CSLPILRNITKQICCCSRVGKAWGRGCQLCPPFGSEGFREIC 422
Cdd:pfam00683    3 CSNPLPGNVTKSECCCTSVGRAWGSPCELCPPPGTDEFRELC 44
TB pfam00683
TB domain; This domain is also known as the 8 cysteine domain. This family includes the hybrid ...
 1323-1365 1.75e-07

TB domain; This domain is also known as the 8 cysteine domain. This family includes the hybrid domains. This cysteine rich repeat is found in TGF binding protein and fibrillin.


Pssm-ID: 459903  Cd Length: 44  Bit Score: 48.81  E-value: 1.75e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 110347412  1323 VCSHPrLDRQATYTECCCLY-GEAWGMDCALCPAQDSDDFEALC 1365
Cdd:pfam00683    2 RCSNP-LPGNVTKSECCCTSvGRAWGSPCELCPPPGTDEFRELC 44
TB pfam00683
TB domain; This domain is also known as the 8 cysteine domain. This family includes the hybrid ...
 1156-1198 4.90e-07

TB domain; This domain is also known as the 8 cysteine domain. This family includes the hybrid domains. This cysteine rich repeat is found in TGF binding protein and fibrillin.


Pssm-ID: 459903  Cd Length: 44  Bit Score: 47.66  E-value: 4.90e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 110347412  1156 CDNILARNVTWQECCC-TVGEGWGSGCriQQCPGTETAEYQSLC 1198
Cdd:pfam00683    3 CSNPLPGNVTKSECCCtSVGRAWGSPC--ELCPPPGTDEFRELC 44
EGF_CA smart00179
Calcium-binding EGF-like domain;
841-877 8.95e-07

Calcium-binding EGF-like domain;


Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 46.86  E-value: 8.95e-07
                            10        20        30
                    ....*....|....*....|....*....|....*..
gi 110347412    841 DVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPR 877
Cdd:smart00179    1 DIDECASGNPCQNGGTCVNTVGSYRCECPPGYTDGRN 37
EGF_CA smart00179
Calcium-binding EGF-like domain;
797-830 1.16e-06

Calcium-binding EGF-like domain;


Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 46.47  E-value: 1.16e-06
                            10        20        30
                    ....*....|....*....|....*....|....
gi 110347412    797 DVDECSSGaPPCGPHGHCTNTEGSFRCSCAPGYR 830
Cdd:smart00179    1 DIDECASG-NPCQNGGTCVNTVGSYRCECPPGYT 33
EGF_CA smart00179
Calcium-binding EGF-like domain;
1012-1053 1.39e-06

Calcium-binding EGF-like domain;


Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 46.09  E-value: 1.39e-06
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|..
gi 110347412   1012 DVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEgarDGRHCV 1053
Cdd:smart00179    1 DIDECASGNPCQNGGTCVNTVGSYRCECPPGYT---DGRNCE 39
EGF_CA cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ...
 797-830 1.84e-06

Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements.


Pssm-ID: 238011  Cd Length: 38  Bit Score: 45.71  E-value: 1.84e-06
                          10        20        30
                  ....*....|....*....|....*....|....
gi 110347412  797 DVDECSSGaPPCGPHGHCTNTEGSFRCSCAPGYR 830
Cdd:cd00054     1 DIDECASG-NPCQNGGTCVNTVGSYRCSCPPGYT 33
EGF_CA cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ...
 1012-1047 5.20e-06

Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements.


Pssm-ID: 238011  Cd Length: 38  Bit Score: 44.55  E-value: 5.20e-06
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 110347412 1012 DVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGAR 1047
Cdd:cd00054     1 DIDECASGNPCQNGGTCVNTVGSYRCSCPPGYTGRN 36
EGF_CA smart00179
Calcium-binding EGF-like domain;
883-918 6.82e-06

Calcium-binding EGF-like domain;


Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 44.16  E-value: 6.82e-06
                            10        20        30
                    ....*....|....*....|....*....|....*..
gi 110347412    883 DVDECSEEDLCQSG-ICTNTDGSFECICPPGHRAGPD 918
Cdd:smart00179    1 DIDECASGNPCQNGgTCVNTVGSYRCECPPGYTDGRN 37
EGF_CA cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ...
 841-873 1.47e-05

Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements.


Pssm-ID: 238011  Cd Length: 38  Bit Score: 43.39  E-value: 1.47e-05
                          10        20        30
                  ....*....|....*....|....*....|...
gi 110347412  841 DVNECLEGDFCFPHGECLNTDGSFACTCAPGYR 873
Cdd:cd00054     1 DIDECASGNPCQNGGTCVNTVGSYRCSCPPGYT 33
EGF_CA cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ...
 634-671 1.88e-05

Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements.


Pssm-ID: 238011  Cd Length: 38  Bit Score: 43.01  E-value: 1.88e-05
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 110347412  634 DVDECtQSPGLCGRGA-CKNLPGSFRCVCPAGFRGSACE 671
Cdd:cd00054     1 DIDEC-ASGNPCQNGGtCVNTVGSYRCSCPPGYTGRNCE 38
EGF_CA smart00179
Calcium-binding EGF-like domain;
320-350 2.89e-05

Calcium-binding EGF-like domain;


Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 42.62  E-value: 2.89e-05
                            10        20        30
                    ....*....|....*....|....*....|..
gi 110347412    320 DVDECATGGRCQHG-ECANTRGGYTCVCPDGF 350
Cdd:smart00179    1 DIDECASGNPCQNGgTCVNTVGSYRCECPPGY 32
EGF_CA pfam07645
Calcium-binding EGF domain;
797-828 3.01e-05

Calcium-binding EGF domain;


Pssm-ID: 429571  Cd Length: 32  Bit Score: 42.22  E-value: 3.01e-05
                           10        20        30
                   ....*....|....*....|....*....|..
gi 110347412   797 DVDECSSGAPPCGPHGHCTNTEGSFRCSCAPG 828
Cdd:pfam07645    1 DVDECATGTHNCPANTVCVNTIGSFECRCPDG 32
EGF_CA cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ...
 883-914 6.12e-05

Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements.


Pssm-ID: 238011  Cd Length: 38  Bit Score: 41.47  E-value: 6.12e-05
                          10        20        30
                  ....*....|....*....|....*....|...
gi 110347412  883 DVDECSEEDLCQ-SGICTNTDGSFECICPPGHR 914
Cdd:cd00054     1 DIDECASGNPCQnGGTCVNTVGSYRCSCPPGYT 33
EGF_CA smart00179
Calcium-binding EGF-like domain;
634-671 8.59e-05

Calcium-binding EGF-like domain;


Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 41.08  E-value: 8.59e-05
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|
gi 110347412    634 DVDECtQSPGLCGRGA-CKNLPGSFRCVCPAGFR-GSACE 671
Cdd:smart00179    1 DIDEC-ASGNPCQNGGtCVNTVGSYRCECPPGYTdGRNCE 39
EGF_CA cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ...
 320-354 1.09e-04

Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements.


Pssm-ID: 238011  Cd Length: 38  Bit Score: 40.70  E-value: 1.09e-04
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 110347412  320 DVDECATGGRCQ-HGECANTRGGYTCVCPDGFLLDS 354
Cdd:cd00054     1 DIDECASGNPCQnGGTCVNTVGSYRCSCPPGYTGRN 36
EGF_CA smart00179
Calcium-binding EGF-like domain;
715-756 1.30e-04

Calcium-binding EGF-like domain;


Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 40.69  E-value: 1.30e-04
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|...
gi 110347412    715 DVDECArSPPPCTYG-RCENTEGSFQCVCPMGFqpnTAGSECE 756
Cdd:smart00179    1 DIDECA-SGNPCQNGgTCVNTVGSYRCECPPGY---TDGRNCE 39
EGF_CA smart00179
Calcium-binding EGF-like domain;
550-586 2.48e-04

Calcium-binding EGF-like domain;


Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 39.92  E-value: 2.48e-04
                            10        20        30
                    ....*....|....*....|....*....|....*...
gi 110347412    550 DVDECRRvPPPCAPG-RCENSPGSFRCVCGPGFRAGPR 586
Cdd:smart00179    1 DIDECAS-GNPCQNGgTCVNTVGSYRCECPPGYTDGRN 37
EGF_3 pfam12947
EGF domain; This family includes a variety of EGF-like domain homologs. This family includes ...
 801-830 2.84e-04

EGF domain; This family includes a variety of EGF-like domain homologs. This family includes the C-terminal domain of the malaria parasite MSP1 protein.


Pssm-ID: 463759 [Multi-domain]  Cd Length: 36  Bit Score: 39.50  E-value: 2.84e-04
                           10        20        30
                   ....*....|....*....|....*....|
gi 110347412   801 CSSGAPPCGPHGHCTNTEGSFRCSCAPGYR 830
Cdd:pfam12947    1 CSDNNGGCHPNATCTNTGGSFTCTCNDGYT 30
EGF_CA smart00179
Calcium-binding EGF-like domain;
592-633 4.94e-04

Calcium-binding EGF-like domain;


Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 39.15  E-value: 4.94e-04
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|..
gi 110347412    592 DVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAaphGASCQ 633
Cdd:smart00179    1 DIDECASGNPCQNGGTCVNTVGSYRCECPPGYTD---GRNCE 39
EGF_CA pfam07645
Calcium-binding EGF domain;
883-912 7.99e-04

Calcium-binding EGF domain;


Pssm-ID: 429571  Cd Length: 32  Bit Score: 38.37  E-value: 7.99e-04
                           10        20        30
                   ....*....|....*....|....*....|..
gi 110347412   883 DVDEC-SEEDLC-QSGICTNTDGSFECICPPG 912
Cdd:pfam07645    1 DVDECaTGTHNCpANTVCVNTIGSFECRCPDG 32
EGF_3 pfam12947
EGF domain; This family includes a variety of EGF-like domain homologs. This family includes ...
 1022-1052 1.02e-03

EGF domain; This family includes a variety of EGF-like domain homologs. This family includes the C-terminal domain of the malaria parasite MSP1 protein.


Pssm-ID: 463759 [Multi-domain]  Cd Length: 36  Bit Score: 37.96  E-value: 1.02e-03
                           10        20        30
                   ....*....|....*....|....*....|.
gi 110347412  1022 CGAHAVCQNLPGSFQCLCDQGYEGarDGRHC 1052
Cdd:pfam12947    8 CHPNATCTNTGGSFTCTCNDGYTG--DGVTC 36
EGF_CA smart00179
Calcium-binding EGF-like domain;
673-707 1.02e-03

Calcium-binding EGF-like domain;


Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 38.00  E-value: 1.02e-03
                            10        20        30
                    ....*....|....*....|....*....|....*.
gi 110347412    673 DVDECAqEPPPCGPG-RCDNTAGSFHCACPAGFRSR 707
Cdd:smart00179    1 DIDECA-SGNPCQNGgTCVNTVGSYRCECPPGYTDG 35
EGF_CA cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ...
 715-750 1.08e-03

Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements.


Pssm-ID: 238011  Cd Length: 38  Bit Score: 38.00  E-value: 1.08e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 110347412  715 DVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNT 750
Cdd:cd00054     1 DIDECASGNPCQNGGTCVNTVGSYRCSCPPGYTGRN 36
EGF_CA cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ...
 673-707 1.17e-03

Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements.


Pssm-ID: 238011  Cd Length: 38  Bit Score: 38.00  E-value: 1.17e-03
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 110347412  673 DVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSR 707
Cdd:cd00054     1 DIDECASGNPCQNGGTCVNTVGSYRCSCPPGYTGR 35
EGF smart00181
Epidermal growth factor-like domain;
323-355 1.50e-03

Epidermal growth factor-like domain;


Pssm-ID: 214544  Cd Length: 35  Bit Score: 37.50  E-value: 1.50e-03
                            10        20        30
                    ....*....|....*....|....*....|...
gi 110347412    323 ECATGGRCQHGECANTRGGYTCVCPDGFLLDSS 355
Cdd:smart00181    1 ECASGGPCSNGTCINTPGSYTCSCPPGYTGDKR 33
EGF_CA cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ...
 1259-1288 1.80e-03

Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements.


Pssm-ID: 238011  Cd Length: 38  Bit Score: 37.62  E-value: 1.80e-03
                          10        20        30
                  ....*....|....*....|....*....|
gi 110347412 1259 DNDECADEEPACEGGRCVNTVGSYHCTCEP 1288
Cdd:cd00054     1 DIDECASGNPCQNGGTCVNTVGSYRCSCPP 30
EGF_CA smart00179
Calcium-binding EGF-like domain;
1259-1288 2.04e-03

Calcium-binding EGF-like domain;


Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 37.23  E-value: 2.04e-03
                            10        20        30
                    ....*....|....*....|....*....|
gi 110347412   1259 DNDECADEEPACEGGRCVNTVGSYHCTCEP 1288
Cdd:smart00179    1 DIDECASGNPCQNGGTCVNTVGSYRCECPP 30
EGF_CA pfam07645
Calcium-binding EGF domain;
320-349 2.20e-03

Calcium-binding EGF domain;


Pssm-ID: 429571  Cd Length: 32  Bit Score: 37.22  E-value: 2.20e-03
                           10        20        30
                   ....*....|....*....|....*....|..
gi 110347412   320 DVDECATGGR-CQHGE-CANTRGGYTCVCPDG 349
Cdd:pfam07645    1 DVDECATGTHnCPANTvCVNTIGSFECRCPDG 32
EGF_CA smart00179
Calcium-binding EGF-like domain;
1537-1571 2.32e-03

Calcium-binding EGF-like domain;


Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 37.23  E-value: 2.32e-03
                            10        20        30
                    ....*....|....*....|....*....|....*.
gi 110347412   1537 DINECDEaeaaSPLCVN-ARCLNTDGSFRCICRPGF 1571
Cdd:smart00179    1 DIDECAS----GNPCQNgGTCVNTVGSYRCECPPGY 32
EGF_CA cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ...
 592-633 3.06e-03

Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements.


Pssm-ID: 238011  Cd Length: 38  Bit Score: 36.85  E-value: 3.06e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 110347412  592 DVDECHRVPPPCDLGRCENTPGSFLCVCPAGYqaapHGASCQ 633
Cdd:cd00054     1 DIDECASGNPCQNGGTCVNTVGSYRCSCPPGY----TGRNCE 38
EGF_CA smart00179
Calcium-binding EGF-like domain;
924-962 3.08e-03

Calcium-binding EGF-like domain;


Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 36.84  E-value: 3.08e-03
                            10        20        30
                    ....*....|....*....|....*....|....*....
gi 110347412    924 DVDECRERGPALCGSqRCENSPGSYRCvrDCDPGYHAGP 962
Cdd:smart00179    1 DIDECASGNPCQNGG-TCVNTVGSYRC--ECPPGYTDGR 36
EGF_CA cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ...
 550-582 3.19e-03

Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements.


Pssm-ID: 238011  Cd Length: 38  Bit Score: 36.85  E-value: 3.19e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 110347412  550 DVDECRRVPPPCAPGRCENSPGSFRCVCGPGFR 582
Cdd:cd00054     1 DIDECASGNPCQNGGTCVNTVGSYRCSCPPGYT 33
EGF_CA smart00179
Calcium-binding EGF-like domain;
968-1011 3.44e-03

Calcium-binding EGF-like domain;


Pssm-ID: 214542 [Multi-domain]  Cd Length: 39  Bit Score: 36.84  E-value: 3.44e-03
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....
gi 110347412    968 DVDECQEYGPEICGAqRCENTPGSYRCTpaCDPGYqpTPGGGCQ 1011
Cdd:smart00179    1 DIDECASGNPCQNGG-TCVNTVGSYRCE--CPPGY--TDGRNCE 39
EGF_CA cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ...
 1537-1575 4.92e-03

Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements.


Pssm-ID: 238011  Cd Length: 38  Bit Score: 36.08  E-value: 4.92e-03
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 110347412 1537 DINECDEAeaaSPLCVNARCLNTDGSFRCICRPGFAPTH 1575
Cdd:cd00054     1 DIDECASG---NPCQNGGTCVNTVGSYRCSCPPGYTGRN 36
EGF_CA pfam07645
Calcium-binding EGF domain;
715-745 7.09e-03

Calcium-binding EGF domain;


Pssm-ID: 429571  Cd Length: 32  Bit Score: 35.68  E-value: 7.09e-03
                           10        20        30
                   ....*....|....*....|....*....|..
gi 110347412   715 DVDECARSPPPCTY-GRCENTEGSFQCVCPMG 745
Cdd:pfam07645    1 DVDECATGTHNCPAnTVCVNTIGSFECRCPDG 32
EGF_CA pfam07645
Calcium-binding EGF domain;
1537-1570 9.25e-03

Calcium-binding EGF domain;


Pssm-ID: 429571  Cd Length: 32  Bit Score: 35.29  E-value: 9.25e-03
                           10        20        30
                   ....*....|....*....|....*....|....
gi 110347412  1537 DINECDEAEAASPlcVNARCLNTDGSFRCICRPG 1570
Cdd:pfam07645    1 DVDECATGTHNCP--ANTVCVNTIGSFECRCPDG 32
EGF_CA pfam07645
Calcium-binding EGF domain;
1012-1042 9.72e-03

Calcium-binding EGF domain;


Pssm-ID: 429571  Cd Length: 32  Bit Score: 35.29  E-value: 9.72e-03
                           10        20        30
                   ....*....|....*....|....*....|..
gi 110347412  1012 DVDECRNRSF-CGAHAVCQNLPGSFQCLCDQG 1042
Cdd:pfam07645    1 DVDECATGTHnCPANTVCVNTIGSFECRCPDG 32
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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