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Conserved domains on  [gi|14270688|ref|NP_009551|]
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Utp20p [Saccharomyces cerevisiae S288C]

Protein Classification

UTP20 family protein( domain architecture ID 10540292)

UTP20 (U three protein 20) family protein similar to Saccharomyces cerevisiae U3 small nucleolar RNA-associated protein 20, also called UTP20, that is involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
DRIM pfam07539
Down-regulated in metastasis; These eukaryotic proteins include DRIM (Down-Regulated In ...
 823-1409 0e+00

Down-regulated in metastasis; These eukaryotic proteins include DRIM (Down-Regulated In Metastasis), which is differentially expressed in metastatic and non-metastatic human breast carcinoma cells. It is believed to be involved in processing of non-coding RNA.


:

Pssm-ID: 462198  Cd Length: 609  Bit Score: 609.96  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14270688    823 WTEVDRNVFLKTLSKFKNIKNVYSATELHDHLMVLLGSRNTDVQKLALDALLAYKNPTLNKYRDNLKNLLDDTLFKDEIT 902
Cdd:pfam07539    1 WSRKDLKALLKLFAKFKNPKALYKSDELYEALLDLLSNGDAEVQKLALDCLLTWKDPAVVPYKENLKNLLDDTRFRDELT 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14270688    903 TFLTENGSQSIKAEDEKVVMPYVLRIFFGRAQVPPTSGQKRS-----RKIAVISVLPNFKKPYINDFLSLASERLDYNY- 976
Cdd:pfam07539   81 VFLQSDEDSVIEPEHRPELMPVLLRILYGRMISKKGSRSSGKagqqaRRKAVLRFLAGLSEEELGLFLDLALGPLKYVSv 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14270688    977 ------FFGNSHQINSSKATLktiRRMTGFVNIVNSTLSVLRTNFPLHTNSVLQPLIYSIAMAYYVLDT---ESTEEVHL 1047
Cdd:pfam07539  161 vdesveFFENGDELLSEVLPL---RRQLGFLNLLEDVLKVLGSKLAPYLPKLLNPLLYCLVAAQRRLDQedeEEEEEGIL 237

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14270688   1048 RKMASNLRQQGLKCLSSVFEFVGNtFDWSTSMEDIYAVVVKPRISHFSDENLQQPSSLLRLFLYWAHNPSLYQFLYYDEF 1127
Cdd:pfam07539  238 LKLLRNIRQLGLKCLVDLFQNFGD-FDWTPYIDAIFEEVISPRLEKLAVENLQSPSALLKLFHTWSKNPRYAPFLVKYDS 316

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14270688   1128 ATATALMDTISNQHVKEAVIGPIIEAADSIIRNP--------VNDDHYVDLVTLICTSCLKILPSLYVKLSDSNS--IST 1197
Cdd:pfam07539  317 AVLPAVIELLSNPKAKPSVVLFVLDIVENLLTLAdeedeeeeDSEDIGSELLLPHVSSLLQHLPALLERSKTPSKelLSR 396

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14270688   1198 FLNLLVSITEmgFIQDDHVRSRLISSLISILKGKLKKLQENDTQKILKILKLIVFNYNCSWSDI--EELYTTISSLFKTF 1275
Cdd:pfam07539  397 ELSILSRLAP--YVTDSEQASSLLDLLLPLLRKPSRRVSPKTKVDLLKILSNLLPLYDCSWDDIlpEKLYKTLSSLFSTF 474

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14270688   1276 DERNLRVSLTELFIELGRKVPELESISKLVADLNSYSSSRMHEYDFPRILSTFKGLIEDGYKSYSELEWLPLLFTFLHFI 1355
Cdd:pfam07539  475 KDRESREALCKVFKALAKKDPELEEVADLVADLNAYSTRRLDEPDFDRRLSAFKKINEELYKSLTARQWLPLLYNCLFFI 554

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....
gi 14270688   1356 NNKEELALRTNASHAIMKFIDFINEKPNLNEASKSISMLKDILLPNIRIGLRDS 1409
Cdd:pfam07539  555 RDEEELAIRSNASHCLKRFIDAAASKSSEEEKEEFEDLLKDVLLPALRRGLRSK 608
DUF6700 pfam20416
Domain of unknown function (DUF6700); This putative domain is found in the UTP20 protein which ...
 1600-1819 4.74e-76

Domain of unknown function (DUF6700); This putative domain is found in the UTP20 protein which associated with the U3 snRNA.


:

Pssm-ID: 466565  Cd Length: 221  Bit Score: 252.07  E-value: 4.74e-76
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14270688   1600 TRDDETIIERMPIAEALVNIVLGLTNDDITNFLPSILTNICQVLRSKSEELRDAVRVTLGKISIILGAEYLVFVIKELMA 1679
Cdd:pfam20416    2 KDEEDEDVLRVPVALAIVKLLQLLPEKSLEVNLPGLLLKLCQFLRSRSQEVRDLARETLVKILETLGPKYLPFILKELKS 81

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14270688   1680 TLKRGSQIHVLSYTVHYILKSMHGVLKHSDLDTSSSMIVKIIMENIFGFAGEEKDSENYHTKVKEIKSNKSYDAGEILAS 1759
Cdd:pfam20416   82 ALTRGYQLHVLSYTVHSLLVALEPTLEPGDLDSCLEDILDIIMDDIFGEVAEEKEVEEITSKMKEAKSSKSYDTFEILAQ 161

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 14270688   1760 NISLTEFGTLLSPVKALLMVRINLRNQNKLSELLRRYLLGLNHNSDSESESILKFCHQLF 1819
Cdd:pfam20416  162 FISFNALHDLLLPLKEILHETESAKTLRKVEELLRRIALGLSANPSLSSEDLLIFCYGLI 221
 
Name Accession Description Interval E-value
DRIM pfam07539
Down-regulated in metastasis; These eukaryotic proteins include DRIM (Down-Regulated In ...
 823-1409 0e+00

Down-regulated in metastasis; These eukaryotic proteins include DRIM (Down-Regulated In Metastasis), which is differentially expressed in metastatic and non-metastatic human breast carcinoma cells. It is believed to be involved in processing of non-coding RNA.


Pssm-ID: 462198  Cd Length: 609  Bit Score: 609.96  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14270688    823 WTEVDRNVFLKTLSKFKNIKNVYSATELHDHLMVLLGSRNTDVQKLALDALLAYKNPTLNKYRDNLKNLLDDTLFKDEIT 902
Cdd:pfam07539    1 WSRKDLKALLKLFAKFKNPKALYKSDELYEALLDLLSNGDAEVQKLALDCLLTWKDPAVVPYKENLKNLLDDTRFRDELT 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14270688    903 TFLTENGSQSIKAEDEKVVMPYVLRIFFGRAQVPPTSGQKRS-----RKIAVISVLPNFKKPYINDFLSLASERLDYNY- 976
Cdd:pfam07539   81 VFLQSDEDSVIEPEHRPELMPVLLRILYGRMISKKGSRSSGKagqqaRRKAVLRFLAGLSEEELGLFLDLALGPLKYVSv 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14270688    977 ------FFGNSHQINSSKATLktiRRMTGFVNIVNSTLSVLRTNFPLHTNSVLQPLIYSIAMAYYVLDT---ESTEEVHL 1047
Cdd:pfam07539  161 vdesveFFENGDELLSEVLPL---RRQLGFLNLLEDVLKVLGSKLAPYLPKLLNPLLYCLVAAQRRLDQedeEEEEEGIL 237

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14270688   1048 RKMASNLRQQGLKCLSSVFEFVGNtFDWSTSMEDIYAVVVKPRISHFSDENLQQPSSLLRLFLYWAHNPSLYQFLYYDEF 1127
Cdd:pfam07539  238 LKLLRNIRQLGLKCLVDLFQNFGD-FDWTPYIDAIFEEVISPRLEKLAVENLQSPSALLKLFHTWSKNPRYAPFLVKYDS 316

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14270688   1128 ATATALMDTISNQHVKEAVIGPIIEAADSIIRNP--------VNDDHYVDLVTLICTSCLKILPSLYVKLSDSNS--IST 1197
Cdd:pfam07539  317 AVLPAVIELLSNPKAKPSVVLFVLDIVENLLTLAdeedeeeeDSEDIGSELLLPHVSSLLQHLPALLERSKTPSKelLSR 396

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14270688   1198 FLNLLVSITEmgFIQDDHVRSRLISSLISILKGKLKKLQENDTQKILKILKLIVFNYNCSWSDI--EELYTTISSLFKTF 1275
Cdd:pfam07539  397 ELSILSRLAP--YVTDSEQASSLLDLLLPLLRKPSRRVSPKTKVDLLKILSNLLPLYDCSWDDIlpEKLYKTLSSLFSTF 474

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14270688   1276 DERNLRVSLTELFIELGRKVPELESISKLVADLNSYSSSRMHEYDFPRILSTFKGLIEDGYKSYSELEWLPLLFTFLHFI 1355
Cdd:pfam07539  475 KDRESREALCKVFKALAKKDPELEEVADLVADLNAYSTRRLDEPDFDRRLSAFKKINEELYKSLTARQWLPLLYNCLFFI 554

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....
gi 14270688   1356 NNKEELALRTNASHAIMKFIDFINEKPNLNEASKSISMLKDILLPNIRIGLRDS 1409
Cdd:pfam07539  555 RDEEELAIRSNASHCLKRFIDAAASKSSEEEKEEFEDLLKDVLLPALRRGLRSK 608
DUF6700 pfam20416
Domain of unknown function (DUF6700); This putative domain is found in the UTP20 protein which ...
 1600-1819 4.74e-76

Domain of unknown function (DUF6700); This putative domain is found in the UTP20 protein which associated with the U3 snRNA.


Pssm-ID: 466565  Cd Length: 221  Bit Score: 252.07  E-value: 4.74e-76
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14270688   1600 TRDDETIIERMPIAEALVNIVLGLTNDDITNFLPSILTNICQVLRSKSEELRDAVRVTLGKISIILGAEYLVFVIKELMA 1679
Cdd:pfam20416    2 KDEEDEDVLRVPVALAIVKLLQLLPEKSLEVNLPGLLLKLCQFLRSRSQEVRDLARETLVKILETLGPKYLPFILKELKS 81

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14270688   1680 TLKRGSQIHVLSYTVHYILKSMHGVLKHSDLDTSSSMIVKIIMENIFGFAGEEKDSENYHTKVKEIKSNKSYDAGEILAS 1759
Cdd:pfam20416   82 ALTRGYQLHVLSYTVHSLLVALEPTLEPGDLDSCLEDILDIIMDDIFGEVAEEKEVEEITSKMKEAKSSKSYDTFEILAQ 161

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 14270688   1760 NISLTEFGTLLSPVKALLMVRINLRNQNKLSELLRRYLLGLNHNSDSESESILKFCHQLF 1819
Cdd:pfam20416  162 FISFNALHDLLLPLKEILHETESAKTLRKVEELLRRIALGLSANPSLSSEDLLIFCYGLI 221
 
Name Accession Description Interval E-value
DRIM pfam07539
Down-regulated in metastasis; These eukaryotic proteins include DRIM (Down-Regulated In ...
 823-1409 0e+00

Down-regulated in metastasis; These eukaryotic proteins include DRIM (Down-Regulated In Metastasis), which is differentially expressed in metastatic and non-metastatic human breast carcinoma cells. It is believed to be involved in processing of non-coding RNA.


Pssm-ID: 462198  Cd Length: 609  Bit Score: 609.96  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14270688    823 WTEVDRNVFLKTLSKFKNIKNVYSATELHDHLMVLLGSRNTDVQKLALDALLAYKNPTLNKYRDNLKNLLDDTLFKDEIT 902
Cdd:pfam07539    1 WSRKDLKALLKLFAKFKNPKALYKSDELYEALLDLLSNGDAEVQKLALDCLLTWKDPAVVPYKENLKNLLDDTRFRDELT 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14270688    903 TFLTENGSQSIKAEDEKVVMPYVLRIFFGRAQVPPTSGQKRS-----RKIAVISVLPNFKKPYINDFLSLASERLDYNY- 976
Cdd:pfam07539   81 VFLQSDEDSVIEPEHRPELMPVLLRILYGRMISKKGSRSSGKagqqaRRKAVLRFLAGLSEEELGLFLDLALGPLKYVSv 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14270688    977 ------FFGNSHQINSSKATLktiRRMTGFVNIVNSTLSVLRTNFPLHTNSVLQPLIYSIAMAYYVLDT---ESTEEVHL 1047
Cdd:pfam07539  161 vdesveFFENGDELLSEVLPL---RRQLGFLNLLEDVLKVLGSKLAPYLPKLLNPLLYCLVAAQRRLDQedeEEEEEGIL 237

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14270688   1048 RKMASNLRQQGLKCLSSVFEFVGNtFDWSTSMEDIYAVVVKPRISHFSDENLQQPSSLLRLFLYWAHNPSLYQFLYYDEF 1127
Cdd:pfam07539  238 LKLLRNIRQLGLKCLVDLFQNFGD-FDWTPYIDAIFEEVISPRLEKLAVENLQSPSALLKLFHTWSKNPRYAPFLVKYDS 316

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14270688   1128 ATATALMDTISNQHVKEAVIGPIIEAADSIIRNP--------VNDDHYVDLVTLICTSCLKILPSLYVKLSDSNS--IST 1197
Cdd:pfam07539  317 AVLPAVIELLSNPKAKPSVVLFVLDIVENLLTLAdeedeeeeDSEDIGSELLLPHVSSLLQHLPALLERSKTPSKelLSR 396

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14270688   1198 FLNLLVSITEmgFIQDDHVRSRLISSLISILKGKLKKLQENDTQKILKILKLIVFNYNCSWSDI--EELYTTISSLFKTF 1275
Cdd:pfam07539  397 ELSILSRLAP--YVTDSEQASSLLDLLLPLLRKPSRRVSPKTKVDLLKILSNLLPLYDCSWDDIlpEKLYKTLSSLFSTF 474

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14270688   1276 DERNLRVSLTELFIELGRKVPELESISKLVADLNSYSSSRMHEYDFPRILSTFKGLIEDGYKSYSELEWLPLLFTFLHFI 1355
Cdd:pfam07539  475 KDRESREALCKVFKALAKKDPELEEVADLVADLNAYSTRRLDEPDFDRRLSAFKKINEELYKSLTARQWLPLLYNCLFFI 554

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....
gi 14270688   1356 NNKEELALRTNASHAIMKFIDFINEKPNLNEASKSISMLKDILLPNIRIGLRDS 1409
Cdd:pfam07539  555 RDEEELAIRSNASHCLKRFIDAAASKSSEEEKEEFEDLLKDVLLPALRRGLRSK 608
DUF6700 pfam20416
Domain of unknown function (DUF6700); This putative domain is found in the UTP20 protein which ...
 1600-1819 4.74e-76

Domain of unknown function (DUF6700); This putative domain is found in the UTP20 protein which associated with the U3 snRNA.


Pssm-ID: 466565  Cd Length: 221  Bit Score: 252.07  E-value: 4.74e-76
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14270688   1600 TRDDETIIERMPIAEALVNIVLGLTNDDITNFLPSILTNICQVLRSKSEELRDAVRVTLGKISIILGAEYLVFVIKELMA 1679
Cdd:pfam20416    2 KDEEDEDVLRVPVALAIVKLLQLLPEKSLEVNLPGLLLKLCQFLRSRSQEVRDLARETLVKILETLGPKYLPFILKELKS 81

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 14270688   1680 TLKRGSQIHVLSYTVHYILKSMHGVLKHSDLDTSSSMIVKIIMENIFGFAGEEKDSENYHTKVKEIKSNKSYDAGEILAS 1759
Cdd:pfam20416   82 ALTRGYQLHVLSYTVHSLLVALEPTLEPGDLDSCLEDILDIIMDDIFGEVAEEKEVEEITSKMKEAKSSKSYDTFEILAQ 161

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 14270688   1760 NISLTEFGTLLSPVKALLMVRINLRNQNKLSELLRRYLLGLNHNSDSESESILKFCHQLF 1819
Cdd:pfam20416  162 FISFNALHDLLLPLKEILHETESAKTLRKVEELLRRIALGLSANPSLSSEDLLIFCYGLI 221
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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