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Conserved domains on  [gi|6679184|ref|NP_032795|]
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ornithine transcarbamylase, mitochondrial isoform 1 precursor [Mus musculus]

Protein Classification

ornithine carbamoyltransferase( domain architecture ID 11414683)

ornithine carbamoyltransferase reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to L-ornithine (ORN) to produce L-citrulline, as part of the urea cycle and L-arginine biosynthesis

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ArgF COG0078
Ornithine carbamoyltransferase [Amino acid transport and metabolism]; Ornithine ...
 35-342 1.46e-165

Ornithine carbamoyltransferase [Amino acid transport and metabolism]; Ornithine carbamoyltransferase is part of the Pathway/BioSystem: Arginine biosynthesis


:

Pssm-ID: 439848 [Multi-domain]  Cd Length: 310  Bit Score: 464.14  E-value: 1.46e-165
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184   35 VQLKGRDLLTLKNFTGEEIQYMLWLSADLKfRIKQKGEYLPLLQGKSLGMIFEKRSTRTRLSTETGFALLGGHPSFLTTQ 114
Cdd:COG0078   1 TNLKGRHFLSLLDLTPEELRALLDLAAELK-AKRKAGIPHRPLKGKTLAMIFEKPSTRTRVSFEVGMAQLGGHAIYLDPG 79

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184  115 DIHLGVNESLTDTARVLSSMTDAVLARVYKQSDLDTLAKEASIPIVNGLSDLYHPIQILADYLTLQEHYGSLKGLTLSWI 194
Cdd:COG0078  80 DSQLGRGESIKDTARVLSRYVDGIMIRTFGHETLEELAKYAGVPVINGLTDLFHPCQALADLLTIREHFGKLKGLKVAYV 159

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184  195 GDGNNILHSIMMSAAKFGMHLQAATPKGYEPDPNIVKLAEQYAKENGTKLSMTNDPLEAARGGNVLITDTWISMGQEDEK 274
Cdd:COG0078 160 GDGNNVANSLLLAAAKLGMDVRIATPEGYEPDPEIVAKAKEIAAESGGSITITHDPAEAVKGADVVYTDVWVSMGQEEEA 239

                       250       260       270       280       290       300
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 6679184  275 KKRLQAFQGYQVTMKTAKVAASDWTFLHCLP-RKPEEVDDEVFYSPRSLVFPEAENRKWTIMAVMVSLL 342
Cdd:COG0078 240 EERIKAFKPYQVNEELMALAKPDAIFMHCLPaHRGEEVTDEVIDGPQSVVFDEAENRLHAQKALLAWLL 308
 
Name Accession Description Interval E-value
ArgF COG0078
Ornithine carbamoyltransferase [Amino acid transport and metabolism]; Ornithine ...
 35-342 1.46e-165

Ornithine carbamoyltransferase [Amino acid transport and metabolism]; Ornithine carbamoyltransferase is part of the Pathway/BioSystem: Arginine biosynthesis


Pssm-ID: 439848 [Multi-domain]  Cd Length: 310  Bit Score: 464.14  E-value: 1.46e-165
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184   35 VQLKGRDLLTLKNFTGEEIQYMLWLSADLKfRIKQKGEYLPLLQGKSLGMIFEKRSTRTRLSTETGFALLGGHPSFLTTQ 114
Cdd:COG0078   1 TNLKGRHFLSLLDLTPEELRALLDLAAELK-AKRKAGIPHRPLKGKTLAMIFEKPSTRTRVSFEVGMAQLGGHAIYLDPG 79

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184  115 DIHLGVNESLTDTARVLSSMTDAVLARVYKQSDLDTLAKEASIPIVNGLSDLYHPIQILADYLTLQEHYGSLKGLTLSWI 194
Cdd:COG0078  80 DSQLGRGESIKDTARVLSRYVDGIMIRTFGHETLEELAKYAGVPVINGLTDLFHPCQALADLLTIREHFGKLKGLKVAYV 159

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184  195 GDGNNILHSIMMSAAKFGMHLQAATPKGYEPDPNIVKLAEQYAKENGTKLSMTNDPLEAARGGNVLITDTWISMGQEDEK 274
Cdd:COG0078 160 GDGNNVANSLLLAAAKLGMDVRIATPEGYEPDPEIVAKAKEIAAESGGSITITHDPAEAVKGADVVYTDVWVSMGQEEEA 239

                       250       260       270       280       290       300
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 6679184  275 KKRLQAFQGYQVTMKTAKVAASDWTFLHCLP-RKPEEVDDEVFYSPRSLVFPEAENRKWTIMAVMVSLL 342
Cdd:COG0078 240 EERIKAFKPYQVNEELMALAKPDAIFMHCLPaHRGEEVTDEVIDGPQSVVFDEAENRLHAQKALLAWLL 308
PRK00779 PRK00779
ornithine carbamoyltransferase; Provisional
 36-342 5.94e-158

ornithine carbamoyltransferase; Provisional


Pssm-ID: 234835 [Multi-domain]  Cd Length: 304  Bit Score: 444.53  E-value: 5.94e-158
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184    36 QLKGRDLLTLKNFTGEEIQYMLWLSADLKfRIKQKGEYLPLLQGKSLGMIFEKRSTRTRLSTETGFALLGGHPSFLTTQD 115
Cdd:PRK00779   1 MLMGRHFLSLDDLSPEELEELLDLAAELK-KKRKAGEPHPPLKGKTLAMIFEKPSTRTRVSFEVGMAQLGGHAIFLSPRD 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184   116 IHLGVNESLTDTARVLSSMTDAVLARVYKQSDLDTLAKEASIPIVNGLSDLYHPIQILADYLTLQEHYGSLKGLTLSWIG 195
Cdd:PRK00779  80 TQLGRGEPIEDTARVLSRYVDAIMIRTFEHETLEELAEYSTVPVINGLTDLSHPCQILADLLTIYEHRGSLKGLKVAWVG 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184   196 DGNNILHSIMMSAAKFGMHLQAATPKGYEPDPNIVklaEQYAKENGTKLSMTNDPLEAARGGNVLITDTWISMGQEDEKK 275
Cdd:PRK00779 160 DGNNVANSLLLAAALLGFDLRVATPKGYEPDPEIV---EKIAKETGASIEVTHDPKEAVKGADVVYTDVWVSMGQEAEAE 236

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 6679184   276 KRLQAFQGYQVTMKTAKVAASDWTFLHCLP-RKPEEVDDEVFYSPRSLVFPEAENRKWTIMAVMVSLL 342
Cdd:PRK00779 237 ERLKAFAPYQVNEELMALAKPDAIFMHCLPaHRGEEVTDEVIDGPQSVVWDEAENRLHAQKALLAWLL 304
orni_carb_tr TIGR00658
ornithine carbamoyltransferase; This family of ornithine carbamoyltransferases (OTCase) is in ...
 40-342 1.30e-150

ornithine carbamoyltransferase; This family of ornithine carbamoyltransferases (OTCase) is in a superfamily with the related enzyme aspartate carbamoyltransferase. Most known examples are anabolic, playing a role in arginine biosynthesis, but some are catabolic. Most OTCases are homotrimers, but the homotrimers are organized into dodecamers built from four trimers in at least two species; the catabolic OTCase of Pseudomonas aeruginosa is allosterically regulated, while OTCase of the extreme thermophile Pyrococcus furiosus shows both allostery and thermophily. [Amino acid biosynthesis, Glutamate family]


Pssm-ID: 129743 [Multi-domain]  Cd Length: 304  Bit Score: 426.38  E-value: 1.30e-150
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184     40 RDLLTLKNFTGEEIQYMLWLSADLKfRIKQKGEYLPLLQGKSLGMIFEKRSTRTRLSTETGFALLGGHPSFLTTQDIHLG 119
Cdd:TIGR00658   1 RHLLSLLDLSPEEIRYLLQLAKKLK-KGKKKGKEHKKLKGKTLALIFEKPSTRTRVSFEVAAYQLGGHPLYLNPNDLQLG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184    120 VNESLTDTARVLSSMTDAVLARVYKQSDLDTLAKEASIPIVNGLSDLYHPIQILADYLTLQEHYGSLKGLTLSWIGDGNN 199
Cdd:TIGR00658  80 RGESIKDTARVLSRYVDGIMARVYKHEDVEELAKYASVPVINGLTDLFHPCQALADLLTIIEHFGKLKGVKVVYVGDGNN 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184    200 ILHSIMMSAAKFGMHLQAATPKGYEPDPNIVKLAEQYAKENGTKLSMTNDPLEAARGGNVLITDTWISMGQEDEKKKRLQ 279
Cdd:TIGR00658 160 VCNSLMLAGAKLGMDVVVATPEGYEPDADIVKKAQEIAKENGGSVELTHDPVEAVKGADVIYTDVWVSMGEEDKKEERLK 239

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 6679184    280 AFQGYQVTMKTAKVAASDWTFLHCLPR-KPEEVDDEVFYSPRSLVFPEAENRKWTIMAVMVSLL 342
Cdd:TIGR00658 240 LFRPYQVNEELMELAKPEVIFMHCLPAhRGEEVTDEVIEGPHSIVFDQAENRLHAQKAVMVALL 303
OTCace pfam00185
Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain;
190-341 2.22e-66

Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain;


Pssm-ID: 425511 [Multi-domain]  Cd Length: 154  Bit Score: 206.31  E-value: 2.22e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184    190 TLSWIGDG-NNILHSIMMSAAKFGMHLQAATPKGYEPDPNIVKLAEQYAKENGTKLSMTNDPLEAARGGNVLITDTWISM 268
Cdd:pfam00185   1 KIAYVGDGhNNVAHSLIIAAAKLGMDVRLATPKGYPPDPEVLDKAKKIAEKSGGSIEITDDPAEAVKGADVVYTDVWQSM 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 6679184    269 GQEDEKKKRLQAFQGYQVTMKTAKVAASDWTFLHCLPRK-PEEVDDEVFYSPRSLVFPEAENRKWTIMAVMVSL 341
Cdd:pfam00185  81 GQEKEREERLKAFKPYQVNEELMKLAKKDAIFMHCLPAHrGEEVTDDVFDGPRSVVFDQAENRLHAQKALLALL 154
 
Name Accession Description Interval E-value
ArgF COG0078
Ornithine carbamoyltransferase [Amino acid transport and metabolism]; Ornithine ...
 35-342 1.46e-165

Ornithine carbamoyltransferase [Amino acid transport and metabolism]; Ornithine carbamoyltransferase is part of the Pathway/BioSystem: Arginine biosynthesis


Pssm-ID: 439848 [Multi-domain]  Cd Length: 310  Bit Score: 464.14  E-value: 1.46e-165
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184   35 VQLKGRDLLTLKNFTGEEIQYMLWLSADLKfRIKQKGEYLPLLQGKSLGMIFEKRSTRTRLSTETGFALLGGHPSFLTTQ 114
Cdd:COG0078   1 TNLKGRHFLSLLDLTPEELRALLDLAAELK-AKRKAGIPHRPLKGKTLAMIFEKPSTRTRVSFEVGMAQLGGHAIYLDPG 79

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184  115 DIHLGVNESLTDTARVLSSMTDAVLARVYKQSDLDTLAKEASIPIVNGLSDLYHPIQILADYLTLQEHYGSLKGLTLSWI 194
Cdd:COG0078  80 DSQLGRGESIKDTARVLSRYVDGIMIRTFGHETLEELAKYAGVPVINGLTDLFHPCQALADLLTIREHFGKLKGLKVAYV 159

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184  195 GDGNNILHSIMMSAAKFGMHLQAATPKGYEPDPNIVKLAEQYAKENGTKLSMTNDPLEAARGGNVLITDTWISMGQEDEK 274
Cdd:COG0078 160 GDGNNVANSLLLAAAKLGMDVRIATPEGYEPDPEIVAKAKEIAAESGGSITITHDPAEAVKGADVVYTDVWVSMGQEEEA 239

                       250       260       270       280       290       300
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 6679184  275 KKRLQAFQGYQVTMKTAKVAASDWTFLHCLP-RKPEEVDDEVFYSPRSLVFPEAENRKWTIMAVMVSLL 342
Cdd:COG0078 240 EERIKAFKPYQVNEELMALAKPDAIFMHCLPaHRGEEVTDEVIDGPQSVVFDEAENRLHAQKALLAWLL 308
PRK00779 PRK00779
ornithine carbamoyltransferase; Provisional
 36-342 5.94e-158

ornithine carbamoyltransferase; Provisional


Pssm-ID: 234835 [Multi-domain]  Cd Length: 304  Bit Score: 444.53  E-value: 5.94e-158
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184    36 QLKGRDLLTLKNFTGEEIQYMLWLSADLKfRIKQKGEYLPLLQGKSLGMIFEKRSTRTRLSTETGFALLGGHPSFLTTQD 115
Cdd:PRK00779   1 MLMGRHFLSLDDLSPEELEELLDLAAELK-KKRKAGEPHPPLKGKTLAMIFEKPSTRTRVSFEVGMAQLGGHAIFLSPRD 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184   116 IHLGVNESLTDTARVLSSMTDAVLARVYKQSDLDTLAKEASIPIVNGLSDLYHPIQILADYLTLQEHYGSLKGLTLSWIG 195
Cdd:PRK00779  80 TQLGRGEPIEDTARVLSRYVDAIMIRTFEHETLEELAEYSTVPVINGLTDLSHPCQILADLLTIYEHRGSLKGLKVAWVG 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184   196 DGNNILHSIMMSAAKFGMHLQAATPKGYEPDPNIVklaEQYAKENGTKLSMTNDPLEAARGGNVLITDTWISMGQEDEKK 275
Cdd:PRK00779 160 DGNNVANSLLLAAALLGFDLRVATPKGYEPDPEIV---EKIAKETGASIEVTHDPKEAVKGADVVYTDVWVSMGQEAEAE 236

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 6679184   276 KRLQAFQGYQVTMKTAKVAASDWTFLHCLP-RKPEEVDDEVFYSPRSLVFPEAENRKWTIMAVMVSLL 342
Cdd:PRK00779 237 ERLKAFAPYQVNEELMALAKPDAIFMHCLPaHRGEEVTDEVIDGPQSVVWDEAENRLHAQKALLAWLL 304
orni_carb_tr TIGR00658
ornithine carbamoyltransferase; This family of ornithine carbamoyltransferases (OTCase) is in ...
 40-342 1.30e-150

ornithine carbamoyltransferase; This family of ornithine carbamoyltransferases (OTCase) is in a superfamily with the related enzyme aspartate carbamoyltransferase. Most known examples are anabolic, playing a role in arginine biosynthesis, but some are catabolic. Most OTCases are homotrimers, but the homotrimers are organized into dodecamers built from four trimers in at least two species; the catabolic OTCase of Pseudomonas aeruginosa is allosterically regulated, while OTCase of the extreme thermophile Pyrococcus furiosus shows both allostery and thermophily. [Amino acid biosynthesis, Glutamate family]


Pssm-ID: 129743 [Multi-domain]  Cd Length: 304  Bit Score: 426.38  E-value: 1.30e-150
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184     40 RDLLTLKNFTGEEIQYMLWLSADLKfRIKQKGEYLPLLQGKSLGMIFEKRSTRTRLSTETGFALLGGHPSFLTTQDIHLG 119
Cdd:TIGR00658   1 RHLLSLLDLSPEEIRYLLQLAKKLK-KGKKKGKEHKKLKGKTLALIFEKPSTRTRVSFEVAAYQLGGHPLYLNPNDLQLG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184    120 VNESLTDTARVLSSMTDAVLARVYKQSDLDTLAKEASIPIVNGLSDLYHPIQILADYLTLQEHYGSLKGLTLSWIGDGNN 199
Cdd:TIGR00658  80 RGESIKDTARVLSRYVDGIMARVYKHEDVEELAKYASVPVINGLTDLFHPCQALADLLTIIEHFGKLKGVKVVYVGDGNN 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184    200 ILHSIMMSAAKFGMHLQAATPKGYEPDPNIVKLAEQYAKENGTKLSMTNDPLEAARGGNVLITDTWISMGQEDEKKKRLQ 279
Cdd:TIGR00658 160 VCNSLMLAGAKLGMDVVVATPEGYEPDADIVKKAQEIAKENGGSVELTHDPVEAVKGADVIYTDVWVSMGEEDKKEERLK 239

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 6679184    280 AFQGYQVTMKTAKVAASDWTFLHCLPR-KPEEVDDEVFYSPRSLVFPEAENRKWTIMAVMVSLL 342
Cdd:TIGR00658 240 LFRPYQVNEELMELAKPEVIFMHCLPAhRGEEVTDEVIEGPHSIVFDQAENRLHAQKAVMVALL 303
PRK02102 PRK02102
ornithine carbamoyltransferase; Validated
 35-344 3.31e-136

ornithine carbamoyltransferase; Validated


Pssm-ID: 179366 [Multi-domain]  Cd Length: 331  Bit Score: 390.79  E-value: 3.31e-136
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184    35 VQLKGRDLLTLKNFTGEEIQYMLWLSADLKfRIKQKGEYLPLLQGKSLGMIFEKRSTRTRLSTETGFALLGGHPSFLTTQ 114
Cdd:PRK02102   3 FNLKGRSFLKLLDFTPEEIEYLIDLSIELK-AAKKAGIEHQYLEGKNIALIFEKTSTRTRCAFEVAAIDLGAHVTYLGPN 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184   115 DIHLGVNESLTDTARVLSSMTDAVLARVYKQSDLDTLAKEASIPIVNGLSDLYHPIQILADYLTLQEHYGSLKGLTLSWI 194
Cdd:PRK02102  82 DSQLGKKESIEDTARVLGRMYDGIEYRGFKQEIVEELAKYSGVPVWNGLTDEWHPTQMLADFMTMKEHFGPLKGLKLAYV 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184   195 GDG-NNILHSIMMSAAKFGMHLQAATPKGYEPDPNIVKLAEQYAKENGTKLSMTNDPLEAARGGNVLITDTWISMGQEDE 273
Cdd:PRK02102 162 GDGrNNMANSLMVGGAKLGMDVRICAPKELWPEEELVALAREIAKETGAKITITEDPEEAVKGADVIYTDVWVSMGEEDE 241

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184   274 KKKRLQAFQGYQVTMKTAKVAA-SDWTFLHCLP------------------RKPEEVDDEVFYSPRSLVFPEAENRKWTI 334
Cdd:PRK02102 242 WEERIKLLKPYQVNMDLMKATGnPDVIFMHCLPafhdtetkvgkeiaekygLKGLEVTDEVFESKYSIVFDEAENRMHTI 321

                        330
                 ....*....|
gi 6679184   335 MAVMVSLLTD 344
Cdd:PRK02102 322 KAVMVATLGD 331
PLN02342 PLN02342
ornithine carbamoyltransferase
 37-342 5.04e-134

ornithine carbamoyltransferase


Pssm-ID: 177976 [Multi-domain]  Cd Length: 348  Bit Score: 385.68  E-value: 5.04e-134
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184    37 LKGRDLLTLKNFTGEEIQYMLWLSADLKFRIKQKGE-YLPLlQGKSLGMIFEKRSTRTRLSTETGFALLGGHPSFLTTQD 115
Cdd:PLN02342  43 SKPKHFLHIDDFDKEEILGLLDRAKEVKALLKSGDRsFQPF-KGKSMAMIFTKPSMRTRVSFETGFFLLGGHALYLGPDD 121

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184   116 IHLGVNESLTDTARVLSSMTDAVLARVYKQSDLDTLAKEASIPIVNGLSDLYHPIQILADYLTLQEHYGSLKGLTLSWIG 195
Cdd:PLN02342 122 IQLGKREETRDIARVLSRYNDIIMARVFAHQDVLDLAEYSSVPVINGLTDYNHPCQIMADALTIIEHIGRLEGTKVVYVG 201

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184   196 DGNNILHSIMMSAAKFGMHLQAATPKGYEPDPNIVklaeQYAKENGT-KLSMTNDPLEAARGGNVLITDTWISMGQEDEK 274
Cdd:PLN02342 202 DGNNIVHSWLLLAAVLPFHFVCACPKGYEPDAKTV----EKARAAGIsKIEITNDPAEAVKGADVVYTDVWASMGQKEEA 277

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 6679184   275 KKRLQAFQGYQVTMKTAKVAASDWTFLHCLPRKPE-EVDDEVFYSPRSLVFPEAENRKWTIMAVMVSLL 342
Cdd:PLN02342 278 EKRKKAFQGFQVNEALMKLAGPQAYFMHCLPAERGvEVTDGVMEAPNSIVFPQAENRMHAQNAIMLHQL 346
putr_carbamoyl TIGR04384
putrescine carbamoyltransferase; Members of this family are putrescine carbamoyltransferase ...
 41-345 2.05e-101

putrescine carbamoyltransferase; Members of this family are putrescine carbamoyltransferase (EC 2.1.3.6). There is some overlapping specificity with ornithine carbamoyltransferase (EC 2.1.3.3). The gene regularly is found next to agmatine deiminase and a carbamate kinase, suggesting a conserved catabolic agmatine deiminase pathway. [Energy metabolism, Amino acids and amines]


Pssm-ID: 275177  Cd Length: 330  Bit Score: 302.34  E-value: 2.05e-101
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184     41 DLLTLKNFTGEEIQYMLWLSADLKFRIKQkGEYLPLLQGKSLGMIFEKRSTRTRLSTETGFALLGGHPSFLTTQDIHLGV 120
Cdd:TIGR04384   1 DFIDTNDFTKEEILDIIDLSLKIKEAIKD-GYYPPLLKNKSLGMIFEQSSTRTRVSFETAMTQLGGHAQYLAPGQIQLGG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184    121 NESLTDTARVLSSMTDAVLARVYKQSDLDTLAKEASIPIVNGLSDLYHPIQILADYLTLQEHYGSLKGL---TLSWIGDG 197
Cdd:TIGR04384  80 HESIEDTARVLSRLVDIIMARVDRHETVVELAKYATVPVINGMSDYNHPTQELGDLFTMIEHLPAGKKLedcKVVFVGDA 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184    198 NNILHSIMMSAAKFGMHLQAATPKGYEPDPNIVKLAEQYAKENGTKLSMTNDPLEAARGGNVLITDTWISM-GQEDEKKK 276
Cdd:TIGR04384 160 TQVCVSLMFICTKMGMDFVHFGPKGYQIPEEWLAIAEANCKVSGGSVTVTDDVDEAVKGADFIYTDVWYGLyDQELSEEE 239

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 6679184    277 RLQAFQ-GYQVTMKTAKVAASDWTFLHCLP-RKPEEVDDEVFYSPRSLVFPEAENRKWTIMAVMVSLLTDY 345
Cdd:TIGR04384 240 RMAIFYpKYQVNPELMAKAGPHAKFMHCLPaSRGEEVTDEVMDSPQSICFDEAENRLTAIRALLVYFLYPR 310
PRK14805 PRK14805
ornithine carbamoyltransferase; Provisional
 40-343 2.61e-98

ornithine carbamoyltransferase; Provisional


Pssm-ID: 237819 [Multi-domain]  Cd Length: 302  Bit Score: 293.13  E-value: 2.61e-98
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184    40 RDLLTLKNFTGEEIQYMLWLSADLKfriKQKGEYLPLLQGKSLGMIFEKRSTRTRLSTETGFALLGGHPSFLTTQDIHLG 119
Cdd:PRK14805   2 KHLLSIKELTQQQLLDLLALAKTIK---ANPAEYRQALAGKSVVMLFEKPSLRTRVSFDIGINKLGGHCLYLDQQNGALG 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184   120 VNESLTDTARVLSSMTDAVLARVYKQSDLDTLAKEASIPIVNGLSDLYHPIQILADYLTLQEHYGSLKGLTLSWIGDGNN 199
Cdd:PRK14805  79 KRESVADFAANLSCWADAIVARVFSHSTIEQLAEHGSVPVINALCDLYHPCQALADFLTLAEQFGDVSKVKLAYVGDGNN 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184   200 ILHSIMMSAAKFGMHLQAATPKGYEPDPNIVKLAEQYAKENGTKLSMTNDpLEAARGGNVLITDTWISMGQEDEKKKRLQ 279
Cdd:PRK14805 159 VTHSLMYGAAILGATMTVICPPGHFPDGQIVAEAQELAAKSGGKLVLTSD-IEAIEGHDAIYTDTWISMGDDTPLAEIKA 237

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 6679184   280 AFQGYQVTMK-TAKVAASdwTFLHCLPRKPE-EVDDEVFYSPRSLVFPEAENRKWTIMAVMVSLLT 343
Cdd:PRK14805 238 KFAPYQVNKAlMEKAGAT--FVMHCQPAHRGvEITSEVMDGEGSLILQQAENRMHAQNAVLVTLLS 301
PRK04284 PRK04284
ornithine carbamoyltransferase; Provisional
 34-344 2.80e-96

ornithine carbamoyltransferase; Provisional


Pssm-ID: 235269 [Multi-domain]  Cd Length: 332  Bit Score: 289.34  E-value: 2.80e-96
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184    34 QVQLKGRDLLTLKNFTGEEIQYMLWLSADLKfRIKQKGEYLPLLQGKSLGMIFEKRSTRTRLSTETGFALLGGHPSFLTT 113
Cdd:PRK04284   1 MKNLRNRSFLTLLDFTPKEIEYLLDLSEDLK-RAKYAGIEVQKLKGKNIALIFEKDSTRTRCAFEVAAYDQGAHVTYLGP 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184   114 QDIHLGVNESLTDTARVLSSMTDAVLARVYKQSDLDTLAKEASIPIVNGLSDLYHPIQILADYLTLQEHY-GSLKGLTLS 192
Cdd:PRK04284  80 TGSQMGKKESTKDTARVLGGMYDGIEYRGFSQRTVETLAEYSGVPVWNGLTDEDHPTQVLADFLTAKEHLkKPYKDIKFT 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184   193 WIGDG-NNILHSIMMSAAKFGMHLQAATPKGYEPDPNIVKLAEQYAKENGTKLSMTNDPLEAARGGNVLITDTWISMGQE 271
Cdd:PRK04284 160 YVGDGrNNVANALMQGAAIMGMDFHLVCPKELNPDDELLNKCKEIAAETGGKITITDDIDEGVKGSDVIYTDVWVSMGEP 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184   272 DEK-KKRLQAFQGYQVTMKTAKVAAS-DWTFLHCLPR------------------KPEEVDDEVFYSPRSLVFPEAENRK 331
Cdd:PRK04284 240 DEVwEERIKLLKPYQVNKEMMKKTGNpNAIFEHCLPSfhdldtkvgkeifekyglKEMEVTDEVFESKASVVFDEAENRM 319

                        330
                 ....*....|...
gi 6679184   332 WTIMAVMVSLLTD 344
Cdd:PRK04284 320 HTIKAVMVATLGE 332
PRK03515 PRK03515
ornithine carbamoyltransferase subunit I; Provisional
 36-342 4.36e-82

ornithine carbamoyltransferase subunit I; Provisional


Pssm-ID: 179587 [Multi-domain]  Cd Length: 336  Bit Score: 253.10  E-value: 4.36e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184    36 QLKGRDLLTLKNFTGEEIQYMLWLSADLKFRiKQKGEYLPLLQGKSLGMIFEKRSTRTRLSTETGFALLGGHPSFLTTQD 115
Cdd:PRK03515   3 QFYQRHFLRLLDFTPAELNSLLQLAAKLKAD-KKNGKEEQKLTGKNIALIFEKDSTRTRCSFEVAAYDQGARVTYLGPSG 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184   116 IHLGVNESLTDTARVLSSMTDAVLARVYKQSDLDTLAKEASIPIVNGLSDLYHPIQILADYLTLQEHY--GSLKGLTLSW 193
Cdd:PRK03515  82 SQIGHKESIKDTARVLGRMYDGIQYRGYGQEIVETLAEYAGVPVWNGLTNEFHPTQLLADLLTMQEHLpgKAFNEMTLAY 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184   194 IGDG-NNILHSIMMSAAKFGMHLQAATPKGYEPDPNIVKLAEQYAKENGTKLSMTNDPLEAARGGNVLITDTWISMGQED 272
Cdd:PRK03515 162 AGDArNNMGNSLLEAAALTGLDLRLVAPKACWPEAALVTECRALAQKNGGNITLTEDIAEGVKGADFIYTDVWVSMGEPK 241

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184   273 EK-KKRLQAFQGYQVTMKTAKVAA-SDWTFLHCLPRKPE-------------------EVDDEVFYSPRSLVFPEAENRK 331
Cdd:PRK03515 242 EVwAERIALLRPYQVNSKMMQLTGnPQVKFLHCLPAFHDdqttlgkkmaeeyglhggmEVTDEVFESAHSIVFDQAENRL 321

                        330
                 ....*....|.
gi 6679184   332 WTIMAVMVSLL 342
Cdd:PRK03515 322 HTIKAVMVATL 332
PRK01713 PRK01713
ornithine carbamoyltransferase; Provisional
 37-342 1.02e-76

ornithine carbamoyltransferase; Provisional


Pssm-ID: 167263 [Multi-domain]  Cd Length: 334  Bit Score: 239.12  E-value: 1.02e-76
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184    37 LKGRDLLTLKNFTGEEIQYMLWLSADLKfRIKQKGEYLPLLQGKSLGMIFEKRSTRTRLSTETGFALLGGHPSFLTTQDI 116
Cdd:PRK01713   5 LKNRHLLSLVNHTEREIKYLLDLSRDLK-RAKYAGTEQQRLKGKNIALIFEKTSTRTRCAFEVAAYDQGAQVTYIDPNSS 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184   117 HLGVNESLTDTARVLSSMTDAVLARVYKQSDLDTLAKEASIPIVNGLSDLYHPIQILADYLTLQEHYGS-LKGLTLSWIG 195
Cdd:PRK01713  84 QIGHKESMKDTARVLGRMYDAIEYRGFKQSIVNELAEYAGVPVFNGLTDEFHPTQMLADVLTMIENCDKpLSEISYVYIG 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184   196 DG-NNILHSIMMSAAKFGMHLQAATPKGYEPDPNIVKLAEQYAKENGTKLSMTNDPLEAARGGNVLITDTWISMGQEDEK 274
Cdd:PRK01713 164 DArNNMGNSLLLIGAKLGMDVRICAPKALLPEASLVEMCEKFAKESGARITVTDDIDKAVKGVDFVHTDVWVSMGEPLET 243

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184   275 -KKRLQAFQGYQVTMKTAKVAAS-DWTFLHCLP---------------RKPE-----EVDDEVFYSPRSLVFPEAENRKW 332
Cdd:PRK01713 244 wGERIKLLMPYQVTPELMKRTGNpKVKFMHCLPafhnsetkvgrqiaeKYPElangiEVTEDVFESPMNIAFEQAENRMH 323

                        330
                 ....*....|
gi 6679184   333 TIMAVMVSLL 342
Cdd:PRK01713 324 TIKAVMVASL 333
OTCace pfam00185
Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain;
190-341 2.22e-66

Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain;


Pssm-ID: 425511 [Multi-domain]  Cd Length: 154  Bit Score: 206.31  E-value: 2.22e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184    190 TLSWIGDG-NNILHSIMMSAAKFGMHLQAATPKGYEPDPNIVKLAEQYAKENGTKLSMTNDPLEAARGGNVLITDTWISM 268
Cdd:pfam00185   1 KIAYVGDGhNNVAHSLIIAAAKLGMDVRLATPKGYPPDPEVLDKAKKIAEKSGGSIEITDDPAEAVKGADVVYTDVWQSM 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 6679184    269 GQEDEKKKRLQAFQGYQVTMKTAKVAASDWTFLHCLPRK-PEEVDDEVFYSPRSLVFPEAENRKWTIMAVMVSL 341
Cdd:pfam00185  81 GQEKEREERLKAFKPYQVNEELMKLAKKDAIFMHCLPAHrGEEVTDDVFDGPRSVVFDQAENRLHAQKALLALL 154
PRK12562 PRK12562
ornithine carbamoyltransferase subunit F; Provisional
 40-342 4.37e-66

ornithine carbamoyltransferase subunit F; Provisional


Pssm-ID: 105755  Cd Length: 334  Bit Score: 211.84  E-value: 4.37e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184    40 RDLLTLKNFTGEEIQYMLWLSADLKFRiKQKGEYLPLLQGKSLGMIFEKRSTRTRLSTETGFALLGGHPSFLTTQDIHLG 119
Cdd:PRK12562   7 KHFLKLLDFTPAELNSLLQLAAKLKAD-KKNGKEVARLTGKNIALIFEKDSTRTRCSFEVAAYDQGARVTYLGPSGSQIG 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184   120 VNESLTDTARVLSSMTDAVLARVYKQSDLDTLAKEASIPIVNGLSDLYHPIQILADYLTLQEHY--GSLKGLTLSWIGDG 197
Cdd:PRK12562  86 HKESIKDTARVLGRMYDGIQYRGHGQEVVETLAEYAGVPVWNGLTNEFHPTQLLADLLTMQEHLpgKAFNEMTLVYAGDA 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184   198 -NNILHSIMMSAAKFGMHLQAATPKGYEPDPNIVKLAEQYAKENGTKLSMTNDPLEAARGGNVLITDTWISMGQEDEK-K 275
Cdd:PRK12562 166 rNNMGNSMLEAAALTGLDLRLVAPQACWPEASLVAECSALAQKHGGKITLTEDIAAGVKGADFIYTDVWVSMGEPKEKwA 245

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184   276 KRLQAFQGYQVTMK-TAKVAASDWTFLHCLPRKPE-------------------EVDDEVFYSPRSLVFPEAENRKWTIM 335
Cdd:PRK12562 246 ERIALLRGYQVNSKmMALTGNPQVKFLHCLPAFHDdqttlgkkmakefglhggmEVTDEVFESPASIVFDQAENRMHTIK 325


                 ....*..
gi 6679184   336 AVMVSLL 342
Cdd:PRK12562 326 AVMVATL 332
OTCace_N pfam02729
Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain;
41-181 6.41e-65

Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain;


Pssm-ID: 460665 [Multi-domain]  Cd Length: 140  Bit Score: 202.27  E-value: 6.41e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184     41 DLLTLKNFTGEEIQYMLWLSADLKfRIKQKGEYLPLLQGKSLGMIFEKRSTRTRLSTETGFALLGGHPSFLTTQDIHLGV 120
Cdd:pfam02729   1 HFLSLEDLSREEIEALLDLAAELK-EARKRGKKLPLLKGKTVALLFEEPSTRTRVSFEVAAKRLGGHVIYLSSSDIQLSS 79

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 6679184    121 NESLTDTARVLSSMTDAVLARVYKQSDLDTLAKEASIPIVNGLSDLYHPIQILADYLTLQE 181
Cdd:pfam02729  80 GESLADTARVLSRYVDAIVIRHFGHEDLEELAEYASVPVINAGGDHEHPTQALADLLTIRE 140
PRK04523 PRK04523
N-acetylornithine carbamoyltransferase; Reviewed
 40-341 7.57e-47

N-acetylornithine carbamoyltransferase; Reviewed


Pssm-ID: 235304 [Multi-domain]  Cd Length: 335  Bit Score: 161.84  E-value: 7.57e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184    40 RDLLTLKNFTGEEIQYMLWLSADLKfrikqKGEYLPLLQGKSLGMIFEKRSTRTRLSTETGFALLGGHPSFLTTQ----- 114
Cdd:PRK04523   4 KHFLNTQDWSRAELDALLTQAAAFK-----RNKLGSALKGKSIALVFFNPSLRTRTSFELGAFQLGGHAVVLQPGkdawp 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184   115 -DIHLGV------NESLTDTARVLSSMTDAVLARVY-KQSD---------LDTLAKEASIPIVNgLSDLYHPIQILADYL 177
Cdd:PRK04523  79 iEFELGAvmdgetEEHIREVARVLSRYVDLIGVRAFpKFVDwskdrqdqvLNSFAKYSTVPVIN-METITHPCQELAHAL 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184   178 TLQEHYGSL---KGLTLSWIGD----GNNILHSIMMSAAKFGMHLQAATPK-GYEPDPNIVKLAEQYAKENGTKLSMTND 249
Cdd:PRK04523 158 ALQEHFGTTlrgKKYVLTWTYHpkplNTAVANSALLIATRLGMDVTLLCPTpDYILDERYMDWAEQNAAESGGSLTVSHD 237

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184   250 PLEAARGGNVLITDTWISM----GQEDEKKKRLQaFQGYQVTMKtaKVAAS-DWTFLHCLP-RKPEEVDDEVFYSPRSLV 323
Cdd:PRK04523 238 IDSAYAGADVVYAKSWGALpffgNWEPEKPIRDQ-YQHFIVDER--KMALTnNGVFSHCLPlRRNVKVTDAVMDSPNCIA 314

                        330
                 ....*....|....*...
gi 6679184   324 FPEAENRKWTIMAVMVSL 341
Cdd:PRK04523 315 IDEAENRLHVQKAIMAAL 332
PRK14804 PRK14804
ornithine carbamoyltransferase; Provisional
 40-342 7.90e-45

ornithine carbamoyltransferase; Provisional


Pssm-ID: 173265 [Multi-domain]  Cd Length: 311  Bit Score: 155.95  E-value: 7.90e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184    40 RDLLTLKNFTGEEIQYMLWLSADLKfriKQKGEYLPLLQGKSLGMIFEKRSTRTRLSTETGFALLGGHPSFLTtqdiHLG 119
Cdd:PRK14804   7 KHLISWEDWSDSEILDLLDFAVHVK---KNRVNYAGHMSGRSLAMLFQKTSTRTRVSFEVAMTEMGGHGIYLD----WMA 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184   120 VNESLTDT---ARVLSSMTDAVLARVYKQSDLDTLAKEASIPIVNGLSDLYHPIQILADYLT--LQEHYGSLKGLTLSWI 194
Cdd:PRK14804  80 SNFQLSDIdleARYLSRNVSVIMARLKKHEDLLVMKNGSQVPVINGCDNMFHPCQSLADIMTiaLDSPEIPLNQKQLTYI 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184   195 GDGNNILHSIMMSAAKFGMHLQAATPkgYEPDPNIVKLAEQYAKENGTkLSMTNDPLEAARGGNVLITDTWISM------ 268
Cdd:PRK14804 160 GVHNNVVNSLIGITAALGIHLTLVTP--IAAKENIHAQTVERAKKKGT-LSWEMNLHKAVSHADYVYTDTWLDMeffndp 236

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 6679184   269 GQEDEKKKRLQAFQGYQVTMKTAKvaASDWTFLHCLP-RKPEEVDDEVFYSPRSLVFPEAENRKWTIMAVMVSLL 342
Cdd:PRK14804 237 SYADKKKQRMELMMPYQINSSLME--KTNAKVMHDMPiHAGYEITREVVLSDRSIIFQQAENRLDAQKAVILKLL 309
pyrB PRK00856
aspartate carbamoyltransferase catalytic subunit;
36-344 8.63e-26

aspartate carbamoyltransferase catalytic subunit;


Pssm-ID: 234849 [Multi-domain]  Cd Length: 305  Bit Score: 104.77  E-value: 8.63e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184    36 QLKGRDLLTLKNFTGEEIQYMLWLSADLKFRIKQKGEYLPLLQGKSLGMIFEKRSTRTRLSTETGFALLGGHpsfltTQD 115
Cdd:PRK00856   2 PLKMKHLLSIEDLSREEIELLLDTAEEFKEVLRREVKKVPLLRGKTVANLFFEPSTRTRLSFELAAKRLGAD-----VIN 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184   116 IHLGVN-----ESLTDTARVLSSM-TDAVLARvYKQSDL-DTLAKEASIPIVN---GLSDlyHPIQILADYLTLQEHYGS 185
Cdd:PRK00856  77 FSASTSsvskgETLADTIRTLSAMgADAIVIR-HPQSGAaRLLAESSDVPVINagdGSHQ--HPTQALLDLLTIREEFGR 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184   186 LKGLTLSWIGDgnnILH-----SIMMSAAKFGMHLQAATPKGyepdpnivkLAEQYAKENGTklsmTNDPLEAARGGNVL 260
Cdd:PRK00856 154 LEGLKVAIVGD---IKHsrvarSNIQALTRLGAEVRLIAPPT---------LLPEGMPEYGV----HTDLDEVIEDADVV 217

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184   261 ITdtwismgqedekkKRLQA--------------FQGYQVTMKTAKVAASDWTFLHCLPRKPE-EVDDEVFYSPRSLVFP 325
Cdd:PRK00856 218 MM-------------LRVQKermdggllpsyeeyKRSYGLTAERLALAKPDAIVMHPGPVNRGvEIASDVADGPQSVIFE 284

                        330       340
                 ....*....|....*....|...
gi 6679184   326 EAEN----RkwtiMAVMVSLLTD 344
Cdd:PRK00856 285 QVTNgvavR----MAVLELLLGG 303
PLN02527 PLN02527
aspartate carbamoyltransferase
 76-345 9.60e-24

aspartate carbamoyltransferase


Pssm-ID: 178142 [Multi-domain]  Cd Length: 306  Bit Score: 99.44  E-value: 9.60e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184    76 LLQGKSLGMIFEKRSTRTRLSTETGFALLGGhpSFLTTQDI----HLGVNESLTDTARVLSSMTDAVLARVYKQSDLDTL 151
Cdd:PLN02527  36 MLKGYLMATLFYEPSTRTRLSFESAMKRLGG--EVLTTENAgefsSAAKGETLEDTIRTVEGYSDIIVLRHFESGAARRA 113

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184   152 AKEASIPIVN-GLSDLYHPIQILADYLTLQEHYGSLKGLTLSWIGDGNN--ILHSIMMSAAKFgmhlqaATPKGYEPDPN 228
Cdd:PLN02527 114 AATAEIPVINaGDGPGQHPTQALLDVYTIQREIGRLDGIKVGLVGDLANgrTVRSLAYLLAKY------EDVKIYFVAPD 187

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184   229 IVKLAE---QYAKENGTKLSMTNDPLEAARGGNVLITdTWISMGQEDEKKKRLQAFQG-YQVTMKTAKVAASDWTFLHCL 304
Cdd:PLN02527 188 VVKMKDdikDYLTSKGVEWEESSDLMEVASKCDVLYQ-TRIQRERFGERIDLYEAARGkYIVDKKVMDVLPKHAVVMHPL 266

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 6679184   305 PRKPE---EVDDEvfysPRSLVFPEAENRKWTIMAVMVSLLTDY 345
Cdd:PLN02527 267 PRLDEittDVDSD----PRAAYFRQAKNGLFIRMALLKLLLGGW 306
PRK07200 PRK07200
aspartate/ornithine carbamoyltransferase family protein; Validated
 85-339 5.93e-20

aspartate/ornithine carbamoyltransferase family protein; Validated


Pssm-ID: 235961 [Multi-domain]  Cd Length: 395  Bit Score: 90.18  E-value: 5.93e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184    85 IFEKRSTRTRLSTETGFALLGghpsfLTTQDIHLGVN-----ESLTDTARVLSSMTDAVLAR---------VYKQ---SD 147
Cdd:PRK07200  65 VFRDNSTRTRFSYASACNLLG-----LEVQDLDEGKSqiahgETVRETANMISFMADVIGIRddmyigkgnAYMRevgAA 139

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184   148 LDTLAKEASIP----IVNGLSDLYHPIQILADYLTLQEHYGSL-----KGLTLSWI-----GDGNNILHSIMMSAAKFGM 213
Cdd:PRK07200 140 VDDGYKQGVLPqrptLVNLQCDIDHPTQSMADLLHLIEHFGGLenlkgKKIAMTWAyspsyGKPLSVPQGIIGLMTRFGM 219

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184   214 HLQAATPKGYEPDPNIVKLAEQYAKENGTKLSMTNDPLEAARGGNVLITDTWI---SMGQE------------DEKKKRL 278
Cdd:PRK07200 220 DVTLAHPEGYDLMPEVVEVAKKNAKASGGSFRQVNSMEEAFKDADIVYPKSWApykVMEERtelyragdhegiKALEKEL 299

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 6679184   279 QA----FQGYQVT---MKTAKvaASDWTFLHCLPR-------KPEEVDDEVFYSPRSLVFPEAENRKWTIMAVMV 339
Cdd:PRK07200 300 LAqnaqHKDWHCTeemMKLTK--DGKALYMHCLPAdisgvscKEGEVTESVFDRYRIALYKEASWKPYIIAAMIF 372
PRK11891 PRK11891
aspartate carbamoyltransferase; Provisional
 7-342 1.44e-18

aspartate carbamoyltransferase; Provisional


Pssm-ID: 183362 [Multi-domain]  Cd Length: 429  Bit Score: 86.07  E-value: 1.44e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184     7 ILLNNAALRKGHTSVVRhfwcgKPVQSQVQLKGR-DLLTLKNFTGEEIQyMLWLSADLKFRIKQKGEYLPLLQGKSLGMI 85
Cdd:PRK11891  59 IVERAAPGEKYTQSVDE-----QPLADQFAFEGKpQLLSVDQFSRDSVE-ALFRVADVMQPIARRQKISRVLEGAVLGNL 132

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184    86 FEKRSTRTRLSTETGFALLGGhpSFLTTQDI---HLGVNESLTDTARVLSSMTDAVLARVYKQSDLDTLAKEASIPIVN- 161
Cdd:PRK11891 133 FFEASTRTRVSFGAAFCRLGG--SVCDTTGFtfsSMAKGESIYDTSRVMSGYVDALVIRHPEQGSVAEFARATNLPVINg 210

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184   162 GLSDLYHPIQILADYLTLQEHYGSL----KGLTLSWIGD---GNNIlHSIMMSAAKF-GMHLQAATPKGYEPDPNIVkla 233
Cdd:PRK11891 211 GDGPGEHPSQALLDLYTIQREFSRLgkivDGAHIALVGDlkyGRTV-HSLVKLLALYrGLKFTLVSPPTLEMPAYIV--- 286

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184   234 EQYAKeNGTKLSMTNDPLEAARGGNVlITDTWIsmgqedeKKKRL--QAFQGY----QVTMKTA-KVAASDWTFLHCLPR 306
Cdd:PRK11891 287 EQISR-NGHVIEQTDDLAAGLRGADV-VYATRI-------QKERFadESFEGYtpdfQINQALVdAVCKPDTLIMHPLPR 357

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|
gi 6679184   307 --KPEEVD--DEVFYSPRSLVFPEAENRKWTIMAVMVSLL 342
Cdd:PRK11891 358 dsRPGANDlsTDLNRDPRLAIFRQTDNGIPVRMAIFAVLL 397
PRK08192 PRK08192
aspartate carbamoyltransferase; Provisional
 36-212 2.94e-16

aspartate carbamoyltransferase; Provisional


Pssm-ID: 169269 [Multi-domain]  Cd Length: 338  Bit Score: 78.62  E-value: 2.94e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184    36 QLKGRDLLTLKNFTGEEIQYMLWLSADLK-FRIKQKgeYLPLLQGKSLGMIFEKRSTRTRLSTETGFALLGGHPSFLT-T 113
Cdd:PRK08192   2 QFQGSHILSVNQLDRDAIQRIFNVADRMEpYALREK--RTRVLEGAILGNLFFEPSTRTRVSFGCAFNLLGGHVRETTgM 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184   114 QDIHLGVNESLTDTARVLSSMTDAVLARVYKQSDLDTLAKEASIPIVNGlSD--LYHPIQILADYLTLQEHygslkgltL 191
Cdd:PRK08192  80 ASSSLSKGESLYDTARVLSTYSDVIAMRHPDAGSVKEFAEGSRVPVING-GDgsNEHPTQALLDLFTIQKE--------L 150

                        170       180
                 ....*....|....*....|.
gi 6679184   192 SWIGDGNNILHSIMMSAAKFG 212
Cdd:PRK08192 151 AHAGRGIDGMHIAMVGDLKFG 171
pyrB PRK13814
aspartate carbamoyltransferase;
42-345 8.94e-07

aspartate carbamoyltransferase;


Pssm-ID: 139876 [Multi-domain]  Cd Length: 310  Bit Score: 50.10  E-value: 8.94e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184    42 LLTLKNFTGEEIQYMLWLSADLKFRIKQKGEYLPLLQGKSLGMIFEKRSTRTRLSTETGFALLGG---HPSfLTTQDIHL 118
Cdd:PRK13814   8 LLNMRSLTRDHIEKLIQRANYFLTQGMEKNSVFETLKGHVVANLFFEPSTRTRNSFEIAAKRLGAmvlNPN-LKISAISK 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184   119 GvnESLTDTARVLSSMtdAVLARVYKQSDLDT---LAKEASIPIV--NGLSDLYHPIQILADYLTLQEHYGSLKGLTLSW 193
Cdd:PRK13814  87 G--ETLFDTIKTLEAM--GVYFFIVRHSENETpeqIAKQLSSGVVinAGDGNHQHPSQALIDLMTIKQHKPHWNKLCVTI 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184   194 IGD--GNNILHSIMMSAAKFGM-HLQAATPKGYEPDP----NIVKLAEqyakengTKLSMTNdpleaarggnvliTDTWI 266
Cdd:PRK13814 163 IGDirHSRVANSLMDGLVTMGVpEIRLVGPSSLLPDKvgndSIKKFTE-------LKPSLLN-------------SDVIV 222

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6679184   267 SMGQEDEKKKR---LQAFQG-YQVTMKTAKVAASDWTFLHCLPRKPE-EVDDEVFYSPRSLVFPEAENRKWTIMAVM-VS 340
Cdd:PRK13814 223 TLRLQKERHDNsvdIDAFRGsFRLTPEKLYSAKPDAIVMHPGPVNREvEINSDVADNQQSVILQQVRNGVAMRMAVLeLF 302


                 ....*
gi 6679184   341 LLTDY 345
Cdd:PRK13814 303 LLRDF 307
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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