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Conserved domains on  [gi|6678760|ref|NP_032892|]
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acyl-protein thioesterase 1 isoform 1 [Mus musculus]

Protein Classification

alpha/beta hydrolase( domain architecture ID 10491393)

alpha/beta hydrolase similar to acyl-protein thioesterase that hydrolyzes fatty acids from S-acylated cysteine residues in proteins

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Abhydrolase_2 pfam02230
Phospholipase/Carboxylesterase; This family consists of both phospholipases and ...
 8-226 1.29e-109

Phospholipase/Carboxylesterase; This family consists of both phospholipases and carboxylesterases with broad substrate specificity, and is structurally related to alpha/beta hydrolases pfam00561.


:

Pssm-ID: 396693 [Multi-domain]  Cd Length: 217  Bit Score: 313.93  E-value: 1.29e-109
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678760      8 APMPAVVPAARKATAAVIFLHGLGDTGHGWAEAFA-GIKSPHIKYICPHAPVMPVTLNMNMAMPSWFDIVGLSPDSQEDE 86
Cdd:pfam02230   1 NGCAEVVSPRDPAQATVIFLHGLGDSGHGWADAAKtEAPLPNIKFIFPHGPEIPVTLNGGMRMPAWFDLVGLSPNAKEDE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678760     87 SGIKQAAETVKALIDQEVKNGIPSNRIILGGFSQGGALSLYTALTTQQKLAGVTALSCWLPLRASFSQGPINSaNRDISV 166
Cdd:pfam02230  81 AGIKNSAETIEELIDAEQKKGIPSSRIIIGGFSQGAMLALYSALTLPLPLGGIVAFSGFLPLPTKFPSHPNLV-TKKTPI 159

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678760    167 LQCHGDCDPLVPLMFGSLTVERLKALINpaNVTFKIYEGMMHSSCQQEMMDVKHFIDKLL 226
Cdd:pfam02230 160 FLIHGEEDPVVPLALGKLAKEYLKTSLN--KVELKIYEGLAHSICGREMQDIKKFLSKHI 217
 
Name Accession Description Interval E-value
Abhydrolase_2 pfam02230
Phospholipase/Carboxylesterase; This family consists of both phospholipases and ...
 8-226 1.29e-109

Phospholipase/Carboxylesterase; This family consists of both phospholipases and carboxylesterases with broad substrate specificity, and is structurally related to alpha/beta hydrolases pfam00561.


Pssm-ID: 396693 [Multi-domain]  Cd Length: 217  Bit Score: 313.93  E-value: 1.29e-109
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678760      8 APMPAVVPAARKATAAVIFLHGLGDTGHGWAEAFA-GIKSPHIKYICPHAPVMPVTLNMNMAMPSWFDIVGLSPDSQEDE 86
Cdd:pfam02230   1 NGCAEVVSPRDPAQATVIFLHGLGDSGHGWADAAKtEAPLPNIKFIFPHGPEIPVTLNGGMRMPAWFDLVGLSPNAKEDE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678760     87 SGIKQAAETVKALIDQEVKNGIPSNRIILGGFSQGGALSLYTALTTQQKLAGVTALSCWLPLRASFSQGPINSaNRDISV 166
Cdd:pfam02230  81 AGIKNSAETIEELIDAEQKKGIPSSRIIIGGFSQGAMLALYSALTLPLPLGGIVAFSGFLPLPTKFPSHPNLV-TKKTPI 159

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678760    167 LQCHGDCDPLVPLMFGSLTVERLKALINpaNVTFKIYEGMMHSSCQQEMMDVKHFIDKLL 226
Cdd:pfam02230 160 FLIHGEEDPVVPLALGKLAKEYLKTSLN--KVELKIYEGLAHSICGREMQDIKKFLSKHI 217
YpfH COG0400
Predicted esterase [General function prediction only];
17-227 1.66e-52

Predicted esterase [General function prediction only];


Pssm-ID: 440169 [Multi-domain]  Cd Length: 200  Bit Score: 168.16  E-value: 1.66e-52
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678760   17 ARKATAAVIFLHGLGDTGHGWAEAFAGIKSPHIKYICPHAPVMPVtlnmnMAMPSWFDIVGLspDSQEDESGIKQAAETV 96
Cdd:COG0400   1 GGPAAPLVVLLHGYGGDEEDLLPLAPELALPGAAVLAPRAPVPEG-----PGGRAWFDLSFL--EGREDEEGLAAAAEAL 73

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678760   97 KALIDQ-EVKNGIPSNRIILGGFSQGGALSLYTALTTQQKLAGVTALSCWLPLRASFsqGPINSANRDISVLQCHGDCDP 175
Cdd:COG0400  74 AAFIDElEARYGIDPERIVLAGFSQGAAMALSLALRRPELLAGVVALSGYLPGEEAL--PAPEAALAGTPVFLAHGTQDP 151

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|..
gi 6678760  176 LVPLMFGSLTVERLKALinPANVTFKIYEgMMHSSCQQEMMDVKHFIDKLLP 227
Cdd:COG0400 152 VIPVERAREAAEALEAA--GADVTYREYP-GGHEISPEELADARAWLAERLA 200
PRK11460 PRK11460
putative hydrolase; Provisional
 25-217 2.89e-04

putative hydrolase; Provisional


Pssm-ID: 183144 [Multi-domain]  Cd Length: 232  Bit Score: 40.79  E-value: 2.89e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678760    25 IFLHGLGDTGHGWAE---AFAgiksPHIkyicPHAPVMPVTLNMNMAMP---SWFDIVGLSpdsqeDESGIKQAAETVKA 98
Cdd:PRK11460  20 LLFHGVGDNPVAMGEigsWFA----PAF----PDALVVSVGGPEPSGNGagrQWFSVQGIT-----EDNRQARVAAIMPT 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678760    99 LID----QEVKNGIPSNRIILGGFSQGGALSLyTALTTQQKLAG-VTALScwlplrASFSQGPiNSANRDISVLQCHGDC 173
Cdd:PRK11460  87 FIEtvryWQQQSGVGASATALIGFSQGAIMAL-EAVKAEPGLAGrVIAFS------GRYASLP-ETAPTATTIHLIHGGE 158

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 6678760   174 DPLVPLMFGSLTVERLKALinPANVTFKIYEGMMHsSCQQEMMD 217
Cdd:PRK11460 159 DPVIDVAHAVAAQEALISL--GGDVTLDIVEDLGH-AIDPRLMQ 199
 
Name Accession Description Interval E-value
Abhydrolase_2 pfam02230
Phospholipase/Carboxylesterase; This family consists of both phospholipases and ...
 8-226 1.29e-109

Phospholipase/Carboxylesterase; This family consists of both phospholipases and carboxylesterases with broad substrate specificity, and is structurally related to alpha/beta hydrolases pfam00561.


Pssm-ID: 396693 [Multi-domain]  Cd Length: 217  Bit Score: 313.93  E-value: 1.29e-109
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678760      8 APMPAVVPAARKATAAVIFLHGLGDTGHGWAEAFA-GIKSPHIKYICPHAPVMPVTLNMNMAMPSWFDIVGLSPDSQEDE 86
Cdd:pfam02230   1 NGCAEVVSPRDPAQATVIFLHGLGDSGHGWADAAKtEAPLPNIKFIFPHGPEIPVTLNGGMRMPAWFDLVGLSPNAKEDE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678760     87 SGIKQAAETVKALIDQEVKNGIPSNRIILGGFSQGGALSLYTALTTQQKLAGVTALSCWLPLRASFSQGPINSaNRDISV 166
Cdd:pfam02230  81 AGIKNSAETIEELIDAEQKKGIPSSRIIIGGFSQGAMLALYSALTLPLPLGGIVAFSGFLPLPTKFPSHPNLV-TKKTPI 159

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678760    167 LQCHGDCDPLVPLMFGSLTVERLKALINpaNVTFKIYEGMMHSSCQQEMMDVKHFIDKLL 226
Cdd:pfam02230 160 FLIHGEEDPVVPLALGKLAKEYLKTSLN--KVELKIYEGLAHSICGREMQDIKKFLSKHI 217
YpfH COG0400
Predicted esterase [General function prediction only];
17-227 1.66e-52

Predicted esterase [General function prediction only];


Pssm-ID: 440169 [Multi-domain]  Cd Length: 200  Bit Score: 168.16  E-value: 1.66e-52
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678760   17 ARKATAAVIFLHGLGDTGHGWAEAFAGIKSPHIKYICPHAPVMPVtlnmnMAMPSWFDIVGLspDSQEDESGIKQAAETV 96
Cdd:COG0400   1 GGPAAPLVVLLHGYGGDEEDLLPLAPELALPGAAVLAPRAPVPEG-----PGGRAWFDLSFL--EGREDEEGLAAAAEAL 73

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678760   97 KALIDQ-EVKNGIPSNRIILGGFSQGGALSLYTALTTQQKLAGVTALSCWLPLRASFsqGPINSANRDISVLQCHGDCDP 175
Cdd:COG0400  74 AAFIDElEARYGIDPERIVLAGFSQGAAMALSLALRRPELLAGVVALSGYLPGEEAL--PAPEAALAGTPVFLAHGTQDP 151

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|..
gi 6678760  176 LVPLMFGSLTVERLKALinPANVTFKIYEgMMHSSCQQEMMDVKHFIDKLLP 227
Cdd:COG0400 152 VIPVERAREAAEALEAA--GADVTYREYP-GGHEISPEELADARAWLAERLA 200
PldB COG2267
Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];
15-224 4.34e-12

Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];


Pssm-ID: 441868 [Multi-domain]  Cd Length: 221  Bit Score: 63.10  E-value: 4.34e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678760   15 PAARKATAAVIFLHGLGDTGHGW---AEAFA--GIksphikyicphAPVMpvtlnmnmampswFDI--VGLSPDSQEDES 87
Cdd:COG2267  22 RPAGSPRGTVVLVHGLGEHSGRYaelAEALAaaGY-----------AVLA-------------FDLrgHGRSDGPRGHVD 77

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678760   88 GIKQAAETVKALIDQEVKNgiPSNRIILGGFSQGGALSLYTALTTQQKLAGVTALS--------CWLPLRASFSQGPINS 159
Cdd:COG2267  78 SFDDYVDDLRAALDALRAR--PGLPVVLLGHSMGGLIALLYAARYPDRVAGLVLLApayradplLGPSARWLRALRLAEA 155

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 6678760  160 ANR-DISVLQCHGDCDPLVPlmfgSLTVERLKALINPaNVTFKIYEGMMH----SSCQQEMM-DVKHFIDK 224
Cdd:COG2267 156 LARiDVPVLVLHGGADRVVP----PEAARRLAARLSP-DVELVLLPGARHellnEPAREEVLaAILAWLER 221
COG4099 COG4099
Predicted peptidase [General function prediction only];
24-210 5.90e-11

Predicted peptidase [General function prediction only];


Pssm-ID: 443275 [Multi-domain]  Cd Length: 235  Bit Score: 60.37  E-value: 5.90e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678760   24 VIFLHGLGDTG--------HG---WAEAFAGIKSPHIkYICPHAPvmpvtlnmnmampswfdivglspdsQEDESGIKQA 92
Cdd:COG4099  52 VLFLHGAGERGtdnekqltHGapkFINPENQAKFPAI-VLAPQCP-------------------------EDDYWSDTKA 105

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678760   93 AETVKALIDQEVKN-GIPSNRIILGGFSQGGALSLYTALTTQQKLAGVtALSCwlplrasfSQGPINSANR--DISVLQC 169
Cdd:COG4099 106 LDAVLALLDDLIAEyRIDPDRIYLTGLSMGGYGTWDLAARYPDLFAAA-VPIC--------GGGDPANAANlkKVPVWIF 176

                       170       180       190       200
                ....*....|....*....|....*....|....*....|.
gi 6678760  170 HGDCDPLVPLMFGSLTVERLKALinPANVTFKIYEGMMHSS 210
Cdd:COG4099 177 HGAKDDVVPVEESRAMVEALKAA--GADVKYTEYPGVGHNS 215
Aes COG0657
Acetyl esterase/lipase [Lipid transport and metabolism];
15-208 1.11e-08

Acetyl esterase/lipase [Lipid transport and metabolism];


Pssm-ID: 440422 [Multi-domain]  Cd Length: 207  Bit Score: 53.34  E-value: 1.11e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678760   15 PAARKATA-AVIFLHG----LG--DTGHGWAEAFA---GIKSPHIKY-ICPHAPVmpvtlnmnmampswfdivglsPDSQ 83
Cdd:COG0657   6 PAGAKGPLpVVVYFHGggwvSGskDTHDPLARRLAaraGAAVVSVDYrLAPEHPF---------------------PAAL 64

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678760   84 EDesgikqAAETVKALIDQEVKNGIPSNRIILGGFSQGGALSLYTALTTQQ----KLAGVTALSCWL-----PLRASFSQ 154
Cdd:COG0657  65 ED------AYAALRWLRANAAELGIDPDRIAVAGDSAGGHLAAALALRARDrggpRPAAQVLIYPVLdltasPLRADLAG 138

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|....*.
gi 6678760  155 GPinsanrdiSVLQCHGDCDPLVP--LMFgsltVERLKALINPanVTFKIYEGMMH 208
Cdd:COG0657 139 LP--------PTLIVTGEADPLVDesEAL----AAALRAAGVP--VELHVYPGGGH 180
LpqC COG3509
Acetyl xylan esterase AxeA and related esterases, LpqC family [Carbohydrate transport and ...
 14-192 1.41e-07

Acetyl xylan esterase AxeA and related esterases, LpqC family [Carbohydrate transport and metabolism];


Pssm-ID: 442732 [Multi-domain]  Cd Length: 284  Bit Score: 50.77  E-value: 1.41e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678760   14 VPA---ARKATAAVIFLHGLGDTGHGwAEAFAGI--KSPHIKYICphapVMPVTLNMNmAMPSWFDIVGLSPDSQEDESG 88
Cdd:COG3509  43 VPAgydGGAPLPLVVALHGCGGSAAD-FAAGTGLnaLADREGFIV----VYPEGTGRA-PGRCWNWFDGRDQRRGRDDVA 116

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678760   89 IkqaaetVKALIDQEVKN-GIPSNRIILGGFSQGGALSLYTALTTQQKLAGVTALSCwLPLRASFSQGPinSANRDISVL 167
Cdd:COG3509 117 F------IAALVDDLAARyGIDPKRVYVTGLSAGGAMAYRLACEYPDVFAAVAPVAG-LPYGAASDAAC--APGRPVPVL 187

                       170       180
                ....*....|....*....|....*
gi 6678760  168 QCHGDCDPLVPLMFGSLTVERLKAL 192
Cdd:COG3509 188 VIHGTADPTVPYAGAEETLAQWAAL 212
DLH COG0412
Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];
8-209 7.44e-07

Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440181 [Multi-domain]  Cd Length: 226  Bit Score: 48.42  E-value: 7.44e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678760    8 APMPA--VVPAARKATAAVIFLH---GLGDTGHGWAEAFA--GIksphikyicphapvmpVTLnmnmaMPSWFDIVGLSP 80
Cdd:COG0412  14 VTLPGylARPAGGGPRPGVVVLHeifGLNPHIRDVARRLAaaGY----------------VVL-----APDLYGRGGPGD 72

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678760   81 DSQE---------DESGIKQAAETVKALIDQEvknGIPSNRIILGGFSQGGALSLYTAlTTQQKLAGVTALSCWLPLRAS 151
Cdd:COG0412  73 DPDEaralmgaldPELLAADLRAALDWLKAQP---EVDAGRVGVVGFCFGGGLALLAA-ARGPDLAAAVSFYGGLPADDL 148

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678760  152 FSQGPinsaNRDISVLQCHGDCDPLVPLMfgslTVERLKALINPANV--TFKIYEGMMHS 209
Cdd:COG0412 149 LDLAA----RIKAPVLLLYGEKDPLVPPE----QVAALEAALAAAGVdvELHVYPGAGHG 200
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
 23-208 3.48e-06

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 46.15  E-value: 3.48e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678760   23 AVIFLHGLGDTGHGWAEAFAGIkSPHIKYICPHAPVMpvtlnmnmampswfdivGLSPDSQEDESgIKQAAETVKALIDQ 102
Cdd:COG0596  25 PVVLLHGLPGSSYEWRPLIPAL-AAGYRVIAPDLRGH-----------------GRSDKPAGGYT-LDDLADDLAALLDA 85

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678760  103 EvknGIPsnRIILGGFSQGGALSLYTALTTQQKLAGVTALS-----------CWLPLRASFSQGPINSANRDIS------ 165
Cdd:COG0596  86 L---GLE--RVVLVGHSMGGMVALELAARHPERVAGLVLVDevlaalaeplrRPGLAPEALAALLRALARTDLRerlari 160

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*.
gi 6678760  166 ---VLQCHGDCDPLVPLmfgsLTVERLKALInpANVTFKIYEGMMH 208
Cdd:COG0596 161 tvpTLVIWGEKDPIVPP----ALARRLAELL--PNAELVVLPGAGH 200
DAP2 COG1506
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];
96-227 4.77e-05

Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];


Pssm-ID: 441115 [Multi-domain]  Cd Length: 234  Bit Score: 43.08  E-value: 4.77e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678760   96 VKALIDQevkNGIPSNRIILGGFSQGGALSLYTALTTQQK------LAGVTALSCWLPLRASFSQG-------------- 155
Cdd:COG1506  81 IDYLAAR---PYVDPDRIGIYGHSYGGYMALLAAARHPDRfkaavaLAGVSDLRSYYGTTREYTERlmggpwedpeayaa 157

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 6678760  156 --PINSANR-DISVLQCHGDCDPLVPLMFGSLTVERLKAliNPANVTFKIYEGMMHSSCQQEMMDVKH----FIDKLLP 227
Cdd:COG1506 158 rsPLAYADKlKTPLLLIHGEADDRVPPEQAERLYEALKK--AGKPVELLVYPGEGHGFSGAGAPDYLErildFLDRHLK 234
PRK11460 PRK11460
putative hydrolase; Provisional
 25-217 2.89e-04

putative hydrolase; Provisional


Pssm-ID: 183144 [Multi-domain]  Cd Length: 232  Bit Score: 40.79  E-value: 2.89e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678760    25 IFLHGLGDTGHGWAE---AFAgiksPHIkyicPHAPVMPVTLNMNMAMP---SWFDIVGLSpdsqeDESGIKQAAETVKA 98
Cdd:PRK11460  20 LLFHGVGDNPVAMGEigsWFA----PAF----PDALVVSVGGPEPSGNGagrQWFSVQGIT-----EDNRQARVAAIMPT 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678760    99 LID----QEVKNGIPSNRIILGGFSQGGALSLyTALTTQQKLAG-VTALScwlplrASFSQGPiNSANRDISVLQCHGDC 173
Cdd:PRK11460  87 FIEtvryWQQQSGVGASATALIGFSQGAIMAL-EAVKAEPGLAGrVIAFS------GRYASLP-ETAPTATTIHLIHGGE 158

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 6678760   174 DPLVPLMFGSLTVERLKALinPANVTFKIYEGMMHsSCQQEMMD 217
Cdd:PRK11460 159 DPVIDVAHAVAAQEALISL--GGDVTLDIVEDLGH-AIDPRLMQ 199
FSH1 pfam03959
Serine hydrolase (FSH1); This is a family of serine hydrolases.
 24-178 7.77e-04

Serine hydrolase (FSH1); This is a family of serine hydrolases.


Pssm-ID: 461110  Cd Length: 208  Bit Score: 39.19  E-value: 7.77e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678760     24 VIFLHGLGDTGHGWAEAFAGI----KSPHIKYICPHAPV-------MPVTLNMNMAMP------SWFdivgLSPDSQEDE 86
Cdd:pfam03959   6 VLCLHGFGQSGEIFRAKTGALrkllKKLGVEFVYLDAPFelaepadLPGSESEKDEGEddepyrAWF----FGDDDTNEY 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6678760     87 SGIKqaaETVKALIDQEVKNGiPSNRIIlgGFSQGGALSLYtALTTQQKLAGVT--------ALSCWLPL----RASFSQ 154
Cdd:pfam03959  82 LGLD---ESLDYVRDYIKENG-PFDGIL--GFSQGAALAAI-LASLLEEGLPLShpplkfaiLFSGFRPRppiyQEYYSE 154

                         170       180
                  ....*....|....*....|....
gi 6678760    155 GPINsanrdISVLQCHGDCDPLVP 178
Cdd:pfam03959 155 DPIQ-----TPSLHVIGELDTVVP 173
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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