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Conserved domains on  [gi|110665738|ref|NP_033510|]
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histone demethylase UTY isoform 1 [Mus musculus]

Protein Classification

KDM6 family histone demethylase( domain architecture ID 11421451)

KDM6 family histone demethylase, similar to lysine-specific demethylase 6A (KDM6A), also called UTX (ubiquitously-transcribed TPR protein on the X chromosome) that specifically demethylates 'Lys-27' of histone H3, and UTY (ubiquitously-transcribed TPR protein on the Y chromosome) that catalyzes trimethylated 'Lys-27' (H3K27me3) demethylation in histone H3

CATH:  1.25.40.10|2.60.120.10
EC:  1.14.11.-
Gene Ontology:  GO:0005515|GO:0032452|GO:0031490|GO:0046872
PubMed:  26059336|21153002|10517866|30708253|22404999|11165500|14697267|19478949
SCOP:  4001344|3001825

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
JmjC pfam02373
JmjC domain, hydroxylase; The JmjC domain belongs to the Cupin superfamily. JmjC-domain ...
 945-1053 1.08e-33

JmjC domain, hydroxylase; The JmjC domain belongs to the Cupin superfamily. JmjC-domain proteins may be protein hydroxylases that catalyze a novel histone modification. This is confirmed to be a hydroxylase: the human JmjC protein named Tyw5p unexpectedly acts in the biosynthesis of a hypermodified nucleoside, hydroxy-wybutosine, in tRNA-Phe by catalysing hydroxylation.


:

Pssm-ID: 396791  Cd Length: 114  Bit Score: 125.49  E-value: 1.08e-33
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738   945 QLCMKVPGSRIPGHQENNNFCSVNINIGPGDCEWFVVPEDYWGVLNDFCEKNN-------LNFLMSSWWPnlEDLYEANV 1017
Cdd:pfam02373    1 WLYLGMPFSTTPWHIEDQGLYSINYLHFGAPKVWYIIPPEYAEKFEKVLSDHFggeqpddLLHLNTIISP--KQLRENGI 78

                           90       100       110
                   ....*....|....*....|....*....|....*.
gi 110665738  1018 PVYRFIQRPGDLVWINAGTVHWVQAIGWCNNITWNV 1053
Cdd:pfam02373   79 PVYRFVQKPGEFVFTFPGWYHQVFNLGFNIAEAVNF 114
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 125-375 2.50e-24

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 104.04  E-value: 2.50e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738  125 AAFLYG---LGLVYFYYNAFQWAIRAFQEVLYVDPNfcrAKEIHLRLGFMFKMNTDYESSLKHFQLAL-IDcnvctLSSV 200
Cdd:COG2956     5 VAAALGwyfKGLNYLLNGQPDKAIDLLEEALELDPE---TVEAHLALGNLYRRRGEYDRAIRIHQKLLeRD-----PDRA 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738  201 EIQFHIAHLYETQRKYHSAKAAYEQLLQIESLPSQVK---ATVLQQLGwmhhnmdligdnttKERYAIQYLQKSLEEDPN 277
Cdd:COG2956    77 EALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALrllAEIYEQEG--------------DWEKAIEVLERLLKLGPE 142

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738  278 SGQSWYFLGRCYSCIGKVQDAFVSYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGILY 357
Cdd:COG2956   143 NAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELY 222

                         250
                  ....*....|....*...
gi 110665738  358 ESCNQPQDAIKCYLNAAR 375
Cdd:COG2956   223 EKLGDPEEALELLRKALE 240
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 68-156 1.07e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


:

Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 43.80  E-value: 1.07e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738   68 LNKAIHFYESLIVKAEGkvESDFFCQLGHFNLLLEDYSKALSSYQRYYSLQTDywkNAAFLYGLGLVYFYYNAFQWAIRA 147
Cdd:COG5010    70 FEESLALLEQALQLDPN--NPELYYNLALLYSRSGDKDEAKEYYEKALALSPD---NPNAYSNLAALLLSLGQDDEAKAA 144


                  ....*....
gi 110665738  148 FQEVLYVDP 156
Cdd:COG5010   145 LQRALGTSP 153
JmjC smart00558
A domain family that is part of the cupin metalloenzyme superfamily; Probable enzymes, but of ...
 911-975 4.73e-04

A domain family that is part of the cupin metalloenzyme superfamily; Probable enzymes, but of unknown functions, that regulate chromatin reorganisation processes (Clissold and Ponting, in press).


:

Pssm-ID: 214721  Cd Length: 58  Bit Score: 39.16  E-value: 4.73e-04
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 110665738    911 QLHELTKLPafvrvvSAGNLLSHVGYTILGMNSVQLC-MKVPGSRIPGHQENNNfcSVNINIGPGD 975
Cdd:smart00558    1 QLWNLAKLP------FKLNLLSDLPEDIPGPDVGPYLyMGMAGSTTPWHIDDYD--LVNYLHQGAG 58
 
Name Accession Description Interval E-value
JmjC pfam02373
JmjC domain, hydroxylase; The JmjC domain belongs to the Cupin superfamily. JmjC-domain ...
 945-1053 1.08e-33

JmjC domain, hydroxylase; The JmjC domain belongs to the Cupin superfamily. JmjC-domain proteins may be protein hydroxylases that catalyze a novel histone modification. This is confirmed to be a hydroxylase: the human JmjC protein named Tyw5p unexpectedly acts in the biosynthesis of a hypermodified nucleoside, hydroxy-wybutosine, in tRNA-Phe by catalysing hydroxylation.


Pssm-ID: 396791  Cd Length: 114  Bit Score: 125.49  E-value: 1.08e-33
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738   945 QLCMKVPGSRIPGHQENNNFCSVNINIGPGDCEWFVVPEDYWGVLNDFCEKNN-------LNFLMSSWWPnlEDLYEANV 1017
Cdd:pfam02373    1 WLYLGMPFSTTPWHIEDQGLYSINYLHFGAPKVWYIIPPEYAEKFEKVLSDHFggeqpddLLHLNTIISP--KQLRENGI 78

                           90       100       110
                   ....*....|....*....|....*....|....*.
gi 110665738  1018 PVYRFIQRPGDLVWINAGTVHWVQAIGWCNNITWNV 1053
Cdd:pfam02373   79 PVYRFVQKPGEFVFTFPGWYHQVFNLGFNIAEAVNF 114
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 125-375 2.50e-24

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 104.04  E-value: 2.50e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738  125 AAFLYG---LGLVYFYYNAFQWAIRAFQEVLYVDPNfcrAKEIHLRLGFMFKMNTDYESSLKHFQLAL-IDcnvctLSSV 200
Cdd:COG2956     5 VAAALGwyfKGLNYLLNGQPDKAIDLLEEALELDPE---TVEAHLALGNLYRRRGEYDRAIRIHQKLLeRD-----PDRA 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738  201 EIQFHIAHLYETQRKYHSAKAAYEQLLQIESLPSQVK---ATVLQQLGwmhhnmdligdnttKERYAIQYLQKSLEEDPN 277
Cdd:COG2956    77 EALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALrllAEIYEQEG--------------DWEKAIEVLERLLKLGPE 142

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738  278 SGQSWYFLGRCYSCIGKVQDAFVSYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGILY 357
Cdd:COG2956   143 NAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELY 222

                         250
                  ....*....|....*...
gi 110665738  358 ESCNQPQDAIKCYLNAAR 375
Cdd:COG2956   223 EKLGDPEEALELLRKALE 240
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 99-370 1.05e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 50.08  E-value: 1.05e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738    99 LLLEDYSKALSSYQRYYSLQTDywkNAAFLYGLGLVYFYYNAFQWAIRAFQEVLYVDPNFCRAkeiHLRLGfMFKM---- 174
Cdd:TIGR02917  340 LRLGRVDEAIATLSPALGLDPD---DPAALSLLGEAYLALGDFEKAAEYLAKATELDPENAAA---RTQLG-ISKLsqgd 412

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738   175 ------------NTDYESSLKHFQLAL-------IDCNVCTLSSVE--------IQFHIAHLYETQRKYHSAKAAYEQLL 227
Cdd:TIGR02917  413 pseaiadletaaQLDPELGRADLLLILsylrsgqFDKALAAAKKLEkkqpdnasLHNLLGAIYLGKGDLAKAREAFEKAL 492

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738   228 QIEslPSQVKATVLQQlgwmhhNMDLIGDNTTKeryAIQYLQKSLEEDPNSGQSWYFLGRCYSCIGKVQDAFVSYRQSID 307
Cdd:TIGR02917  493 SIE--PDFFPAAANLA------RIDIQEGNPDD---AIQRFEKVLTIDPKNLRAILALAGLYLRTGNEEEAVAWLEKAAE 561

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 110665738   308 KSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGILYESCNQPQDAIKCY 370
Cdd:TIGR02917  562 LNPQEIEPALALAQYYLGKGQLKKALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSF 624
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 68-156 1.07e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 43.80  E-value: 1.07e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738   68 LNKAIHFYESLIVKAEGkvESDFFCQLGHFNLLLEDYSKALSSYQRYYSLQTDywkNAAFLYGLGLVYFYYNAFQWAIRA 147
Cdd:COG5010    70 FEESLALLEQALQLDPN--NPELYYNLALLYSRSGDKDEAKEYYEKALALSPD---NPNAYSNLAALLLSLGQDDEAKAA 144


                  ....*....
gi 110665738  148 FQEVLYVDP 156
Cdd:COG5010   145 LQRALGTSP 153
MamA NF040959
magnetosome protein MamA; Magnetosomes are special lipid-bound organelles that comprise ...
 101-189 1.63e-04

magnetosome protein MamA; Magnetosomes are special lipid-bound organelles that comprise magnetic mineral crystals in magnetotactic bacteria (MTB). Magnetosomes are important for MTB to search for preferred microaerophilic environment. Proteins of this family typically contain five tetra-trico-peptide repeat (TPR) motifs. Based on structural analyses, MamA forms a large homooligomer through self-recognition to regulate protein-protein interaction in magnetosomes.


Pssm-ID: 468889 [Multi-domain]  Cd Length: 204  Bit Score: 44.29  E-value: 1.63e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738  101 LEDYSKALSSYQRYYSLQTDywkNAAFLYGLGLVYFYYNAFQWAIRAFQEVLYVDPNFCRakeIHLRLGFMFKMNTDYES 180
Cdd:NF040959  118 IKDYEKAVEDLEEALEEKPD---NFNLNYRLGLALDGLGQYDKAIEAFQKALELDPNEIK---YHQAIGFMYVQKGDHET 191


                  ....*....
gi 110665738  181 SLKHFQLAL 189
Cdd:NF040959  192 AAEHFKKAM 200
TPR_1 pfam00515
Tetratricopeptide repeat;
125-158 4.56e-04

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 38.56  E-value: 4.56e-04
                           10        20        30
                   ....*....|....*....|....*....|....
gi 110665738   125 AAFLYGLGLVYFYYNAFQWAIRAFQEVLYVDPNF 158
Cdd:pfam00515    1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
JmjC smart00558
A domain family that is part of the cupin metalloenzyme superfamily; Probable enzymes, but of ...
 911-975 4.73e-04

A domain family that is part of the cupin metalloenzyme superfamily; Probable enzymes, but of unknown functions, that regulate chromatin reorganisation processes (Clissold and Ponting, in press).


Pssm-ID: 214721  Cd Length: 58  Bit Score: 39.16  E-value: 4.73e-04
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 110665738    911 QLHELTKLPafvrvvSAGNLLSHVGYTILGMNSVQLC-MKVPGSRIPGHQENNNfcSVNINIGPGD 975
Cdd:smart00558    1 QLWNLAKLP------FKLNLLSDLPEDIPGPDVGPYLyMGMAGSTTPWHIDDYD--LVNYLHQGAG 58
 
Name Accession Description Interval E-value
JmjC pfam02373
JmjC domain, hydroxylase; The JmjC domain belongs to the Cupin superfamily. JmjC-domain ...
 945-1053 1.08e-33

JmjC domain, hydroxylase; The JmjC domain belongs to the Cupin superfamily. JmjC-domain proteins may be protein hydroxylases that catalyze a novel histone modification. This is confirmed to be a hydroxylase: the human JmjC protein named Tyw5p unexpectedly acts in the biosynthesis of a hypermodified nucleoside, hydroxy-wybutosine, in tRNA-Phe by catalysing hydroxylation.


Pssm-ID: 396791  Cd Length: 114  Bit Score: 125.49  E-value: 1.08e-33
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738   945 QLCMKVPGSRIPGHQENNNFCSVNINIGPGDCEWFVVPEDYWGVLNDFCEKNN-------LNFLMSSWWPnlEDLYEANV 1017
Cdd:pfam02373    1 WLYLGMPFSTTPWHIEDQGLYSINYLHFGAPKVWYIIPPEYAEKFEKVLSDHFggeqpddLLHLNTIISP--KQLRENGI 78

                           90       100       110
                   ....*....|....*....|....*....|....*.
gi 110665738  1018 PVYRFIQRPGDLVWINAGTVHWVQAIGWCNNITWNV 1053
Cdd:pfam02373   79 PVYRFVQKPGEFVFTFPGWYHQVFNLGFNIAEAVNF 114
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 125-375 2.50e-24

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 104.04  E-value: 2.50e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738  125 AAFLYG---LGLVYFYYNAFQWAIRAFQEVLYVDPNfcrAKEIHLRLGFMFKMNTDYESSLKHFQLAL-IDcnvctLSSV 200
Cdd:COG2956     5 VAAALGwyfKGLNYLLNGQPDKAIDLLEEALELDPE---TVEAHLALGNLYRRRGEYDRAIRIHQKLLeRD-----PDRA 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738  201 EIQFHIAHLYETQRKYHSAKAAYEQLLQIESLPSQVK---ATVLQQLGwmhhnmdligdnttKERYAIQYLQKSLEEDPN 277
Cdd:COG2956    77 EALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALrllAEIYEQEG--------------DWEKAIEVLERLLKLGPE 142

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738  278 SGQSWYFLGRCYSCIGKVQDAFVSYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGILY 357
Cdd:COG2956   143 NAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELY 222

                         250
                  ....*....|....*...
gi 110665738  358 ESCNQPQDAIKCYLNAAR 375
Cdd:COG2956   223 EKLGDPEEALELLRKALE 240
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
200-437 4.13e-24

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 102.78  E-value: 4.13e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738  200 VEIQFHIAHLYETQRKYHSAKAAYEQLLQIEslPSQVKAtvLQQLGWMHHNMdligdnttkERY--AIQYLQKSLEEDPN 277
Cdd:COG0457     8 AEAYNNLGLAYRRLGRYEEAIEDYEKALELD--PDDAEA--LYNLGLAYLRL---------GRYeeALADYEQALELDPD 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738  278 SGQSWYFLGRCYSCIGKVQDAFVSYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGILY 357
Cdd:COG0457    75 DAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIAL 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738  358 ESCNQPQDAIKCYlNAARSKSCNNTSALTSRIKFLQAQLCNLPQSSLQNKTKLLPSIEEAWSLPIPAELTSRQGAMNTAQ 437
Cdd:COG0457   155 EKLGRYEEALELL-EKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLAL 233
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 166-442 1.35e-22

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 99.03  E-value: 1.35e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738  166 LRLGFMFKMNTDYESSLKHFQLAL-IDcnvctLSSVEIQFHIAHLYETQRKYHSAKAAYEQLLQIEslpsQVKATVLQQL 244
Cdd:COG2956    12 YFKGLNYLLNGQPDKAIDLLEEALeLD-----PETVEAHLALGNLYRRRGEYDRAIRIHQKLLERD----PDRAEALLEL 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738  245 GWMHHNMDLigdnttKERyAIQYLQKSLEEDPNSGQSWYFLGRCYSCIGKVQDAFVSYRQSIDKSEASADTWCSIGVLYQ 324
Cdd:COG2956    83 AQDYLKAGL------LDR-AEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYL 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738  325 QQNQPMDALQAYICAVQLDHGHAAAWMDLGILYESCNQPQDAIKCYLNAARSKScNNTSALtSRIKFLQAQLCNLPQ--S 402
Cdd:COG2956   156 EQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDP-DYLPAL-PRLAELYEKLGDPEEalE 233

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|
gi 110665738  403 SLQNKTKLLPSIEEAWSLpipAELTSRQGAMNTAQQSVSD 442
Cdd:COG2956   234 LLRKALELDPSDDLLLAL---ADLLERKEGLEAALALLER 270
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
123-314 2.05e-19

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 88.91  E-value: 2.05e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738  123 KNAAFLYGLGLVYFYYNAFQWAIRAFQEVLYVDPNFCRAkeiHLRLGFMFKMNTDYESSLKHFQLAL-IDcnvctLSSVE 201
Cdd:COG0457     6 DDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEA---LYNLGLAYLRLGRYEEALADYEQALeLD-----PDDAE 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738  202 IQFHIAHLYETQRKYHSAKAAYEQLLQIEslPSQVKAtvLQQLGWMHHNMdligdnttkERY--AIQYLQKSLEEDPNSG 279
Cdd:COG0457    78 ALNNLGLALQALGRYEEALEDYDKALELD--PDDAEA--LYNLGLALLEL---------GRYdeAIEAYERALELDPDDA 144

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 110665738  280 QSWYFLGRCYSCIGKVQDAFVSYRQSIDKSEASAD 314
Cdd:COG0457   145 DALYNLGIALEKLGRYEEALELLEKLEAAALAALL 179
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 264-370 3.05e-19

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 85.06  E-value: 3.05e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738  264 AIQYLQKSLEEDPNSGQSWYFLGRCYSCIGKVQDAFVSYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLD 343
Cdd:COG4235     2 AIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALD 81

                          90       100
                  ....*....|....*....|....*..
gi 110665738  344 HGHAAAWMDLGILYESCNQPQDAIKCY 370
Cdd:COG4235    82 PDNPEALYLLGLAAFQQGDYAEAIAAW 108
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
272-373 4.47e-18

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 85.06  E-value: 4.47e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738  272 LEEDPNSGQSWYFLGRCYSCIGKVQDAFVSYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWM 351
Cdd:COG0457     1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALN 80

                          90       100
                  ....*....|....*....|..
gi 110665738  352 DLGILYESCNQPQDAIKCYLNA 373
Cdd:COG0457    81 NLGLALQALGRYEEALEDYDKA 102
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 68-375 4.97e-18

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 85.55  E-value: 4.97e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738   68 LNKAIHFYESLIVKAEGKVESDFfcQLGHFNLLLEDYSKALSSYQRYYSLQTDywkNAAFLYGLGLVYFYYNAFQWAIRA 147
Cdd:COG2956    24 PDKAIDLLEEALELDPETVEAHL--ALGNLYRRRGEYDRAIRIHQKLLERDPD---RAEALLELAQDYLKAGLLDRAEEL 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738  148 FQEVLYVDPNfcrakeihlrlgfmfkmntdyesslkhfqlalidcnvctlsSVEIQFHIAHLYETQRKYHSAKAAYEQLL 227
Cdd:COG2956    99 LEKLLELDPD-----------------------------------------DAEALRLLAEIYEQEGDWEKAIEVLERLL 137

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738  228 QIeslpSQVKATVLQQLGwmhhnMDLIGDNTTKEryAIQYLQKSLEEDPNSGQSWYFLGRCYSCIGKVQDAFVSYRQSID 307
Cdd:COG2956   138 KL----GPENAHAYCELA-----ELYLEQGDYDE--AIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALE 206

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 110665738  308 KSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGhAAAWMDLGILYESCNQPQDAIKCYLNAAR 375
Cdd:COG2956   207 QDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPS-DDLLLALADLLERKEGLEAALALLERQLR 273
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 264-419 4.24e-17

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 86.59  E-value: 4.24e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738  264 AIQYLQKSLEEDPNSGQSWYFLGRCYSCIGKVQDAFVSYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLD 343
Cdd:COG3914    97 ALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELD 176

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 110665738  344 HGHAAAWMDLGILYESCNQPQDAIKCYLNAARsKSCNNTSALTSRIkFLQAQLCNLPQSS-LQNKTKLLPSIEEAWS 419
Cdd:COG3914   177 PDNAEALNNLGNALQDLGRLEEAIAAYRRALE-LDPDNADAHSNLL-FALRQACDWEVYDrFEELLAALARGPSELS 251
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 264-375 2.75e-15

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 74.07  E-value: 2.75e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738  264 AIQYLQKSLEEDPNSGQSWYFLGRCYSCIGKVQDAFVSYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLD 343
Cdd:COG4783    23 AEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLD 102

                          90       100       110
                  ....*....|....*....|....*....|..
gi 110665738  344 HGHAAAWMDLGILYESCNQPQDAIKCYLNAAR 375
Cdd:COG4783   103 PEHPEAYLRLARAYRALGRPDEAIAALEKALE 134
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 293-424 2.20e-14

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 77.73  E-value: 2.20e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738  293 GKVQDAFVSYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGILYESCNQPQDAIKCYLN 372
Cdd:COG3914    92 GRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRR 171

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 110665738  373 AARSKScNNTSALTSRIKFLQaQLCNLPQS--SLQNKTKLLPSIEEAWSLPIPA 424
Cdd:COG3914   172 ALELDP-DNAEALNNLGNALQ-DLGRLEEAiaAYRRALELDPDNADAHSNLLFA 223
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 200-343 7.29e-13

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 67.14  E-value: 7.29e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738  200 VEIQFHIAHLYETQRKYHSAKAAYEQLLQIEslPSQVKAtvLQQLGWMHHNMDligdnttKERYAIQYLQKSLEEDPNSG 279
Cdd:COG4783     4 AEALYALAQALLLAGDYDEAEALLEKALELD--PDNPEA--FALLGEILLQLG-------DLDEAIVLLHEALELDPDEP 72

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 110665738  280 QSWYFLGRCYSCIGKVQDAFVSYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLD 343
Cdd:COG4783    73 EARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELD 136
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 67-275 5.16e-12

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 67.83  E-value: 5.16e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738   67 LLNKAIHFYESLIVKAEGKVESdfFCQLGHFNLLLEDYSKALSSYQRYYSLQTDywkNAAFLYGLGLVYFYYNAFQWAIR 146
Cdd:COG2956    91 LLDRAEELLEKLLELDPDDAEA--LRLLAEIYEQEGDWEKAIEVLERLLKLGPE---NAHAYCELAELYLEQGDYDEAIE 165

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738  147 AFQEVLYVDPNFCRAkeiHLRLGFMFKMNTDYESSLKHFQLAL-IDcnvctLSSVEIQFHIAHLYETQRKYHSAKAAYEQ 225
Cdd:COG2956   166 ALEKALKLDPDCARA---LLLLAELYLEQGDYEEAIAALERALeQD-----PDYLPALPRLAELYEKLGDPEEALELLRK 237

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 110665738  226 LLQIESLPSQV--KATVLQQLGwmhhnmdligdnttKERYAIQYLQKSLEED 275
Cdd:COG2956   238 ALELDPSDDLLlaLADLLERKE--------------GLEAALALLERQLRRH 275
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
68-248 1.55e-11

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 65.80  E-value: 1.55e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738   68 LNKAIHFYESLIVKAEGKVESdfFCQLGHFNLLLEDYSKALSSYQRYYSLQTDywkNAAFLYGLGLVYFYYNAFQWAIRA 147
Cdd:COG0457    24 YEEAIEDYEKALELDPDDAEA--LYNLGLAYLRLGRYEEALADYEQALELDPD---DAEALNNLGLALQALGRYEEALED 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738  148 FQEVLYVDPNFCRAkeiHLRLGFMFKMNTDYESSLKHFQLAL-IDCNvctlsSVEIQFHIAHLYETQRKYHSAKAAYEQL 226
Cdd:COG0457    99 YDKALELDPDDAEA---LYNLGLALLELGRYDEAIEAYERALeLDPD-----DADALYNLGIALEKLGRYEEALELLEKL 170

                         170       180
                  ....*....|....*....|..
gi 110665738  227 LQIESLPSQVKATVLQQLGWMH 248
Cdd:COG0457   171 EAAALAALLAAALGEAALALAA 192
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 93-189 2.41e-10

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 59.63  E-value: 2.41e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738   93 QLGHFNLLLEDYSKALSSYQRYYSLQTDywkNAAFLYGLGLVYFYYNAFQWAIRAFQEVLYVDPNFCRAkeiHLRLGFMF 172
Cdd:COG4235    22 LLGRAYLRLGRYDEALAAYEKALRLDPD---NADALLDLAEALLAAGDTEEAEELLERALALDPDNPEA---LYLLGLAA 95

                          90
                  ....*....|....*..
gi 110665738  173 KMNTDYESSLKHFQLAL 189
Cdd:COG4235    96 FQQGDYAEAIAAWQKLL 112
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 121-370 1.07e-09

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 62.70  E-value: 1.07e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738  121 YWKNAAFLYGLGLVYFYYNAFQWAIRAFQEVLYVDPNFCRAKEIHLRLgfmFKMNTDYESSLKHFQLAL-IDCNvctlsS 199
Cdd:COG3914    40 ALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALL---LQALGRYEEALALYRRALaLNPD-----N 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738  200 VEIQFHIAHLYETQRKYHSAKAAYEQLLQIEslPSQVKAtvLQQLGWMHHNMDLIGDnttkeryAIQYLQKSLEEDPNSG 279
Cdd:COG3914   112 AEALFNLGNLLLALGRLEEALAALRRALALN--PDFAEA--YLNLGEALRRLGRLEE-------AIAALRRALELDPDNA 180

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738  280 QSWYFLGRCYSCIGKVQDAFVSYRQSIDKsEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGILYES 359
Cdd:COG3914   181 EALNNLGNALQDLGRLEEAIAAYRRALEL-DPDNADAHSNLLFALRQACDWEVYDRFEELLAALARGPSELSPFALLYLP 259

                         250
                  ....*....|.
gi 110665738  360 CNQPQDAIKCY 370
Cdd:COG3914   260 DDDPAELLALA 270
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 280-375 4.97e-09

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 55.97  E-value: 4.97e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738  280 QSWYFLGRCYSCIGKVQDAFVSYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGILYES 359
Cdd:COG4783     5 EALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLK 84

                          90
                  ....*....|....*.
gi 110665738  360 CNQPQDAIKCYLNAAR 375
Cdd:COG4783    85 AGDYDEALALLEKALK 100
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
264-343 5.69e-09

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 54.41  E-value: 5.69e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738  264 AIQYLQKSLEEDPNSGQSWYFLGRCYSCIGKVQDAfVSYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLD 343
Cdd:COG3063    11 AEEYYEKALELDPDNADALNNLGLLLLEQGRYDEA-IALEKALKLDPNNAEALLNLAELLLELGDYDEALAYLERALELD 89
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
275-368 7.35e-09

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 57.62  E-value: 7.35e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738  275 DPNSGQSWYFLGRCYSCIGKVQDAFVSYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLG 354
Cdd:COG4785    69 LPDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRG 148

                          90
                  ....*....|....
gi 110665738  355 ILYESCNQPQDAIK 368
Cdd:COG4785   149 IALYYLGRYELAIA 162
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 264-343 8.96e-09

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 55.74  E-value: 8.96e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738  264 AIQYLQKSLEEDPNSGQSWYFLGRCYSCIGKVQDAFVSYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLD 343
Cdd:COG5010    73 SLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTS 152
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 281-395 1.16e-08

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 57.82  E-value: 1.16e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738  281 SWYFLGRCYSCIGKVQDAFVSYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGILYESC 360
Cdd:COG2956    10 GWYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKA 89

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 110665738  361 NQPQDAIKCYLNAARSKScNNTSALTSRIKFLQAQ 395
Cdd:COG2956    90 GLLDRAEELLEKLLELDP-DDAEALRLLAEIYEQE 123
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 264-376 1.66e-08

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 54.97  E-value: 1.66e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738  264 AIQYLQKSLEEDPNSGQSWYFLGRCYSCIGKVQDAFVSYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLD 343
Cdd:COG5010    39 EDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALS 118

                          90       100       110
                  ....*....|....*....|....*....|...
gi 110665738  344 HGHAAAWMDLGILYESCNQPQDAIKCYLNAARS 376
Cdd:COG5010   119 PDNPNAYSNLAALLLSLGQDDEAKAALQRALGT 151
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 125-278 3.76e-08

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 53.66  E-value: 3.76e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738  125 AAFLYGLGLVYFYYNAFQWAIRAFQEVLYVDPNFCRAkeiHLRLGFMFKMNTDYESSLKHFQLALIDCNvctlSSVEIQF 204
Cdd:COG4783     4 AEALYALAQALLLAGDYDEAEALLEKALELDPDNPEA---FALLGEILLQLGDLDEAIVLLHEALELDP----DEPEARL 76

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 110665738  205 HIAHLYETQRKYHSAKAAYEQLLQIEslPSQvkATVLQQLGWMHHNMDligdnttKERYAIQYLQKSLEEDPNS 278
Cdd:COG4783    77 NLGLALLKAGDYDEALALLEKALKLD--PEH--PEAYLRLARAYRALG-------RPDEAIAALEKALELDPDD 139
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 68-189 6.45e-08

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 52.89  E-value: 6.45e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738   68 LNKAIHFYESLIvkAEGKVESDFFCQLGHFNLLLEDYSKALSSYQRYYSLQTDywkNAAFLYGLGLVYFYYNAFQWAIRA 147
Cdd:COG4783    20 YDEAEALLEKAL--ELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPD---EPEARLNLGLALLKAGDYDEALAL 94

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 110665738  148 FQEVLYVDPNFcraKEIHLRLGFMFKMNTDYESSLKHFQLAL 189
Cdd:COG4783    95 LEKALKLDPEH---PEAYLRLARAYRALGRPDEAIAALEKAL 133
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 199-314 8.86e-08

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 52.32  E-value: 8.86e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738  199 SVEIQFHIAHLYETQRKYHSAKAAYEQLLQIEslPSqvKATVLQQLGWMHHNMDligdNTTKeryAIQYLQKSLEEDPNS 278
Cdd:COG4235    16 DAEGWLLLGRAYLRLGRYDEALAAYEKALRLD--PD--NADALLDLAEALLAAG----DTEE---AEELLERALALDPDN 84

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 110665738  279 GQSWYFLGRCYSCIGKVQDAFVSYRQSIDKSEASAD 314
Cdd:COG4235    85 PEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAP 120
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
293-375 3.70e-07

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 49.40  E-value: 3.70e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738  293 GKVQDAFVSYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQaYICAVQLDHGHAAAWMDLGILYESCNQPQDAIKCYLN 372
Cdd:COG3063     6 GDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEALAYLER 84


                  ...
gi 110665738  373 AAR 375
Cdd:COG3063    85 ALE 87
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 123-244 1.32e-06

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 48.85  E-value: 1.32e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738  123 KNAAFLYGLGLVYFYYNAFQWAIRAFQEVLYVDPNFcraKEIHLRLGFMFKMNTDYESSLKHFQLAL-IDCNvctlsSVE 201
Cdd:COG4235    15 NDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDN---ADALLDLAEALLAAGDTEEAEELLERALaLDPD-----NPE 86

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 110665738  202 IQFHIAHLYETQRKYHSAKAAYEQLLQIesLPSQVKATVLQQL 244
Cdd:COG4235    87 ALYLLGLAAFQQGDYAEAIAAWQKLLAL--LPADAPARLLEAS 127
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 99-232 5.64e-06

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 47.65  E-value: 5.64e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738   99 LLLEDYSKALSSYQRYYSLQTDYWKNAAFLYGLGLVYFYYNAFQWAIRAFQEVLYVDPNFcraKEIHLRLGFMFKMNTDY 178
Cdd:COG5010    28 EAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNN---PELYYNLALLYSRSGDK 104

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 110665738  179 ESSLKHFQLALIDCNvctlSSVEIQFHIAHLYETQRKYHSAKAAYEQLLQIESL 232
Cdd:COG5010   105 DEAKEYYEKALALSP----DNPNAYSNLAALLLSLGQDDEAKAALQRALGTSPL 154
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
91-161 8.08e-06

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 48.37  E-value: 8.08e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 110665738   91 FCQLGHFNLLLEDYSKALSSYQRYYSLQTDYwknAAFLYGLGLVYFYYNAFQWAIRAFQEVLYVDPNFCRA 161
Cdd:COG4785   110 YNNRGLAYLLLGDYDAALEDFDRALELDPDY---AYAYLNRGIALYYLGRYELAIADLEKALELDPNDPER 177
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 99-370 1.05e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 50.08  E-value: 1.05e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738    99 LLLEDYSKALSSYQRYYSLQTDywkNAAFLYGLGLVYFYYNAFQWAIRAFQEVLYVDPNFCRAkeiHLRLGfMFKM---- 174
Cdd:TIGR02917  340 LRLGRVDEAIATLSPALGLDPD---DPAALSLLGEAYLALGDFEKAAEYLAKATELDPENAAA---RTQLG-ISKLsqgd 412

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738   175 ------------NTDYESSLKHFQLAL-------IDCNVCTLSSVE--------IQFHIAHLYETQRKYHSAKAAYEQLL 227
Cdd:TIGR02917  413 pseaiadletaaQLDPELGRADLLLILsylrsgqFDKALAAAKKLEkkqpdnasLHNLLGAIYLGKGDLAKAREAFEKAL 492

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738   228 QIEslPSQVKATVLQQlgwmhhNMDLIGDNTTKeryAIQYLQKSLEEDPNSGQSWYFLGRCYSCIGKVQDAFVSYRQSID 307
Cdd:TIGR02917  493 SIE--PDFFPAAANLA------RIDIQEGNPDD---AIQRFEKVLTIDPKNLRAILALAGLYLRTGNEEEAVAWLEKAAE 561

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 110665738   308 KSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGILYESCNQPQDAIKCY 370
Cdd:TIGR02917  562 LNPQEIEPALALAQYYLGKGQLKKALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSF 624
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 93-281 2.70e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 48.54  E-value: 2.70e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738    93 QLGHFNLLLEDySKALSSYQRYYSLQTDYWKNAAFLYGLGLVYFYYNAFQWAIRAFQEVLYVDP---NFCRAKEIHLRLG 169
Cdd:TIGR02917  672 QIGLAQLLLAA-KRTESAKKIAKSLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKALKRAPssqNAIKLHRALLASG 750

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738   170 FMFKMNTDYESSLKhfqlalIDCNvctlsSVEIQFHIAHLYETQRKYHSAKAAYEQLLQIEslPSQvkATVLQQLGWMHH 249
Cdd:TIGR02917  751 NTAEAVKTLEAWLK------THPN-----DAVLRTALAELYLAQKDYDKAIKHYQTVVKKA--PDN--AVVLNNLAWLYL 815

                          170       180       190
                   ....*....|....*....|....*....|..
gi 110665738   250 NMdligdnttKERYAIQYLQKSLEEDPNSGQS 281
Cdd:TIGR02917  816 EL--------KDPRALEYAERALKLAPNIPAI 839
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
134-230 4.72e-05

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 43.24  E-value: 4.72e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738  134 VYFYYNAFQWAIRAFQEVLYVDPNFCRAkeiHLRLGFMFKMNTDYESSLKhFQLAL-IDCNvctlsSVEIQFHIAHLYET 212
Cdd:COG3063     1 LYLKLGDLEEAEEYYEKALELDPDNADA---LNNLGLLLLEQGRYDEAIA-LEKALkLDPN-----NAEALLNLAELLLE 71

                          90
                  ....*....|....*...
gi 110665738  213 QRKYHSAKAAYEQLLQIE 230
Cdd:COG3063    72 LGDYDEALAYLERALELD 89
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 264-336 4.88e-05

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 43.83  E-value: 4.88e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 110665738  264 AIQYLQKSLEEDPNS---GQSWYFLGRCYSCIGKVQDAFVSYRQSID---KSEASADTWCSIGVLYQQQNQPMDALQAY 336
Cdd:COG1729    12 AIAAFKAFLKRYPNSplaPDALYWLGEAYYALGDYDEAAEAFEKLLKrypDSPKAPDALLKLGLSYLELGDYDKARATL 90
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 103-189 5.22e-05

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 43.83  E-value: 5.22e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738  103 DYSKALSSYQRYYSL--QTDYWKNAafLYGLGLVYFYYNAFQWAIRAFQEVLYVDPNFCRAKEIHLRLGFMFKMNTDYES 180
Cdd:COG1729     8 DYDEAIAAFKAFLKRypNSPLAPDA--LYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKAPDALLKLGLSYLELGDYDK 85


                  ....*....
gi 110665738  181 SLKHFQLAL 189
Cdd:COG1729    86 ARATLEELI 94
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 68-156 1.07e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 43.80  E-value: 1.07e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738   68 LNKAIHFYESLIVKAEGkvESDFFCQLGHFNLLLEDYSKALSSYQRYYSLQTDywkNAAFLYGLGLVYFYYNAFQWAIRA 147
Cdd:COG5010    70 FEESLALLEQALQLDPN--NPELYYNLALLYSRSGDKDEAKEYYEKALALSPD---NPNAYSNLAALLLSLGQDDEAKAA 144


                  ....*....
gi 110665738  148 FQEVLYVDP 156
Cdd:COG5010   145 LQRALGTSP 153
MamA NF040959
magnetosome protein MamA; Magnetosomes are special lipid-bound organelles that comprise ...
 101-189 1.63e-04

magnetosome protein MamA; Magnetosomes are special lipid-bound organelles that comprise magnetic mineral crystals in magnetotactic bacteria (MTB). Magnetosomes are important for MTB to search for preferred microaerophilic environment. Proteins of this family typically contain five tetra-trico-peptide repeat (TPR) motifs. Based on structural analyses, MamA forms a large homooligomer through self-recognition to regulate protein-protein interaction in magnetosomes.


Pssm-ID: 468889 [Multi-domain]  Cd Length: 204  Bit Score: 44.29  E-value: 1.63e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738  101 LEDYSKALSSYQRYYSLQTDywkNAAFLYGLGLVYFYYNAFQWAIRAFQEVLYVDPNFCRakeIHLRLGFMFKMNTDYES 180
Cdd:NF040959  118 IKDYEKAVEDLEEALEEKPD---NFNLNYRLGLALDGLGQYDKAIEAFQKALELDPNEIK---YHQAIGFMYVQKGDHET 191


                  ....*....
gi 110665738  181 SLKHFQLAL 189
Cdd:NF040959  192 AAEHFKKAM 200
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 94-373 2.03e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 45.84  E-value: 2.03e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738    94 LGHFNLLLEDYSKALSSYQRYYSLQTDywkNAAFLYGLGLVYFYYNAFQWAIRAFQEVLYVDPNFCRAKeihLRLGFMFK 173
Cdd:TIGR02917  607 LGRAQLAAGDLNKAVSSFKKLLALQPD---SALALLLLADAYAVMKNYAKAITSLKRALELKPDNTEAQ---IGLAQLLL 680

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738   174 MNTDYESSLKHFQlaliDCNVCTLSSVEIQFHIAHLYETQRKYHSAKAAYEQLLQIESLPSQVK--ATVLQQLGwmhhnm 251
Cdd:TIGR02917  681 AAKRTESAKKIAK----SLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKALKRAPSSQNAIklHRALLASG------ 750

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738   252 dligdNTTKeryAIQYLQKSLEEDPNSGQSWYFLGRCYSCIGKVQDAFVSYRQSIDKSEASADTWCSIGVLYQQQNQPmD 331
Cdd:TIGR02917  751 -----NTAE---AVKTLEAWLKTHPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKKAPDNAVVLNNLAWLYLELKDP-R 821

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|...
gi 110665738   332 ALQAYICAVQLDHGhAAAWMD-LGILYESCNQPQDAIKCYLNA 373
Cdd:TIGR02917  822 ALEYAERALKLAPN-IPAILDtLGWLLVEKGEADRALPLLRKA 863
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 322-395 2.22e-04

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 45.37  E-value: 2.22e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 110665738  322 LYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGILYESCNQPQDAIKCYLNAARSKScNNTSALTSRIKFLQAQ 395
Cdd:COG3914    87 LLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNP-DFAEAYLNLGEALRRL 159
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 160-370 3.16e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 45.07  E-value: 3.16e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738   160 RAKEIHLRLGFMFKMNTDYESSLKHFQ-LALIDCNvctlsSVEIQFHIAHLYETQRKYHSAKAAYEQLLQIEslPSQVKA 238
Cdd:TIGR02917  599 DSPEAWLMLGRAQLAAGDLNKAVSSFKkLLALQPD-----SALALLLLADAYAVMKNYAKAITSLKRALELK--PDNTEA 671

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738   239 TVLQ-QLgwmhhnmdLIGDNTTKERYAI-QYLQKSLEEDPnSGQSwyFLGRCYSCIGKVQDAFVSYRQSIdKSEASADTW 316
Cdd:TIGR02917  672 QIGLaQL--------LLAAKRTESAKKIaKSLQKQHPKAA-LGFE--LEGDLYLRQKDYPAAIQAYRKAL-KRAPSSQNA 739

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 110665738   317 CSIGVLYQQQNQPMDALQAYIcAVQLDH-GHAAAWMDLGILYESCNQPQDAIKCY 370
Cdd:TIGR02917  740 IKLHRALLASGNTAEAVKTLE-AWLKTHpNDAVLRTALAELYLAQKDYDKAIKHY 793
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 106-276 3.36e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 42.64  E-value: 3.36e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738  106 KALSSYQRYYSLQTDYWKNAAFLYGLGLVYFYYNAFQWAIRAFQEVLYVDPNFCRAKEIHLRLGfmfkmntDYESSLKHF 185
Cdd:COG5010     5 EGFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLG-------DFEESLALL 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738  186 QLAL-IDCNvctlsSVEIQFHIAHLYETQRKYHSAKAAYEQLLQIEslPSQVKAtvlqqlgwmHHNMDLIGDNTTKERYA 264
Cdd:COG5010    78 EQALqLDPN-----NPELYYNLALLYSRSGDKDEAKEYYEKALALS--PDNPNA---------YSNLAALLLSLGQDDEA 141

                         170
                  ....*....|..
gi 110665738  265 IQYLQKSLEEDP 276
Cdd:COG5010   142 KAALQRALGTSP 153
TPR_1 pfam00515
Tetratricopeptide repeat;
125-158 4.56e-04

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 38.56  E-value: 4.56e-04
                           10        20        30
                   ....*....|....*....|....*....|....
gi 110665738   125 AAFLYGLGLVYFYYNAFQWAIRAFQEVLYVDPNF 158
Cdd:pfam00515    1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
JmjC smart00558
A domain family that is part of the cupin metalloenzyme superfamily; Probable enzymes, but of ...
 911-975 4.73e-04

A domain family that is part of the cupin metalloenzyme superfamily; Probable enzymes, but of unknown functions, that regulate chromatin reorganisation processes (Clissold and Ponting, in press).


Pssm-ID: 214721  Cd Length: 58  Bit Score: 39.16  E-value: 4.73e-04
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 110665738    911 QLHELTKLPafvrvvSAGNLLSHVGYTILGMNSVQLC-MKVPGSRIPGHQENNNfcSVNINIGPGD 975
Cdd:smart00558    1 QLWNLAKLP------FKLNLLSDLPEDIPGPDVGPYLyMGMAGSTTPWHIDDYD--LVNYLHQGAG 58
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 199-345 6.18e-04

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 43.36  E-value: 6.18e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738  199 SVEIQFHIAHLYETQRKYHSAkaayEQLLQiESLPSQVKATVLQQLGwmhhnmDLIGDNTTKeryAIQYLQKSLEEDPNS 278
Cdd:COG3071   192 DPELAAAYARALIALGDHDEA----ERLLR-EALKRQWDPRLVRLYG------RLQGGDPAK---QLKRAEKWLKKHPND 257

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738  279 GQSWYFLGR-CYSC--IGKVQDAFvsyRQSIdKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHG 345
Cdd:COG3071   258 PDLLLALGRlCLRNqlWGKAREYL---EAAL-ALRPSAEAYAELARLLEQLGDPEEAAEHYRKALALALG 323
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
101-189 6.33e-04

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 42.59  E-value: 6.33e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738  101 LEDYSKALSSYQRYYSLQTDYwknAAFLYGLGLVYFYYNAFQWAIRAFQEVLYVDPNFCRAkeiHLRLGFMFKMNTDYES 180
Cdd:COG4785    86 LGDYDLAIADFDQALELDPDL---AEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYA---YLNRGIALYYLGRYEL 159


                  ....*....
gi 110665738  181 SLKHFQLAL 189
Cdd:COG4785   160 AIADLEKAL 168
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
322-395 9.92e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 39.38  E-value: 9.92e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 110665738  322 LYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGILYESCNQPQDAIKcyLNAARSKSCNNTSALTSRIKFLQAQ 395
Cdd:COG3063     1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA--LEKALKLDPNNAEALLNLAELLLEL 72
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
264-364 2.91e-03

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 40.67  E-value: 2.91e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738  264 AIQYLQKSLEEDPNSGQSWYFLGRCYSCIGKVQDAFVSYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLD 343
Cdd:COG4785    92 AIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYELAIADLEKALELD 171

                          90       100
                  ....*....|....*....|.
gi 110665738  344 HGHAAAWMDLGILYESCNQPQ 364
Cdd:COG4785   172 PNDPERALWLYLAERKLDPEK 192
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
68-160 3.17e-03

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 38.23  E-value: 3.17e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738   68 LNKAIHFYESLIVKAEGkvESDFFCQLGHFNLLLEDYSKALSsYQRYYSLQTDywkNAAFLYGLGLVYFYYNAFQWAIRA 147
Cdd:COG3063     8 LEEAEEYYEKALELDPD--NADALNNLGLLLLEQGRYDEAIA-LEKALKLDPN---NAEALLNLAELLLELGDYDEALAY 81

                          90
                  ....*....|...
gi 110665738  148 FQEVLYVDPNFCR 160
Cdd:COG3063    82 LERALELDPSALR 94
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 93-157 5.14e-03

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 38.05  E-value: 5.14e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 110665738   93 QLGHFNLLLEDYSKALSSYQRYYSLQTDYWKNAAFLYGLGLVYFYYNAFQWAIRAFQEVLYVDPN 157
Cdd:COG1729    35 WLGEAYYALGDYDEAAEAFEKLLKRYPDSPKAPDALLKLGLSYLELGDYDKARATLEELIKKYPD 99
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 135-228 9.74e-03

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 37.28  E-value: 9.74e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738  135 YFYYNAFQWAIRAFQEVLYVDPNFCRAKEIHLRLGFMFKMNTDYESSLKHFQlALIDCNVCTLSSVEIQFHIAHLYETQR 214
Cdd:COG1729     3 LLKAGDYDEAIAAFKAFLKRYPNSPLAPDALYWLGEAYYALGDYDEAAEAFE-KLLKRYPDSPKAPDALLKLGLSYLELG 81

                          90
                  ....*....|....
gi 110665738  215 KYHSAKAAYEQLLQ 228
Cdd:COG1729    82 DYDKARATLEELIK 95
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 310-395 9.85e-03

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 37.86  E-value: 9.85e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 110665738  310 EASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGILYESCNQPQDAIKcYLNAARSKSCNNTSALTSRI 389
Cdd:COG4783     1 AACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIV-LLHEALELDPDEPEARLNLG 79


                  ....*.
gi 110665738  390 KFLQAQ 395
Cdd:COG4783    80 LALLKA 85
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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